Motif ID: TGIF1.p2

Z-value: 3.172


Transcription factors associated with TGIF1.p2:

Gene SymbolEntrez IDGene Name
TGIF1 7050 TGFB-induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TGIF1chr18_+_3447607-0.812.9e-51Click!


Activity profile for motif TGIF1.p2.

activity profile for motif TGIF1.p2


Sorted Z-values histogram for motif TGIF1.p2

Sorted Z-values for motif TGIF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TGIF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_5248180 82.041 NM_000518
HBB
hemoglobin, beta
chr8_+_80523048 65.290 NM_001199214
NM_007029
STMN2

stathmin-like 2

chr12_-_9268513 59.342 A2M
alpha-2-macroglobulin
chr19_+_45409003 47.019 NM_000041
APOE
apolipoprotein E
chr3_+_45067750 42.103 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr12_-_9268475 41.329 A2M
alpha-2-macroglobulin
chr19_-_39390168 39.464 NM_012237
NM_001193286
NM_030593
SIRT2


sirtuin 2


chr12_-_9268522 39.133 NM_000014
A2M
alpha-2-macroglobulin
chr4_+_113739203 38.873 NM_001127493
ANK2
ankyrin 2, neuronal
chr6_+_32407618 38.757 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr6_-_108145507 37.937 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr1_-_11907741 37.835 NM_006172
NPPA
natriuretic peptide A
chr14_+_100150596 37.816 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr12_-_9268440 37.686 A2M
alpha-2-macroglobulin
chr17_+_41857802 37.132 NM_001136483
C17orf105
chromosome 17 open reading frame 105
chr10_-_73848263 36.306 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_+_30951414 35.752 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr16_+_30710461 34.827 NM_006662
SRCAP
Snf2-related CREBBP activator protein
chr3_+_35722428 34.583 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr7_-_137028533 33.644 NM_002825
PTN
pleiotrophin
chr14_-_21493122 33.260 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr18_+_54318561 32.691 NM_015285
NM_052834
WDR7

WD repeat domain 7

chr19_-_36643770 32.327 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr9_-_33447527 32.218 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr4_-_176733901 31.535 GPM6A
glycoprotein M6A
chr4_-_176923572 31.421 NM_005277
NM_201592
GPM6A

glycoprotein M6A

chr7_+_95401817 30.989 NM_001135556
NM_001135557
NM_004411
DYNC1I1


dynein, cytoplasmic 1, intermediate chain 1


chr1_+_163038395 30.613 NM_001102445
RGS4
regulator of G-protein signaling 4
chr12_+_101988746 30.505 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr22_-_36013303 30.156 NM_005368
NM_203378
MB

myoglobin

chr22_-_50523737 29.859 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chrX_+_101380659 29.686 NM_080390
TCEAL2
transcription elongation factor A (SII)-like 2
chr11_-_5271035 29.621 NM_000559
HBG1
hemoglobin, gamma A
chr17_-_28257017 29.496 NM_033389
SSH2
slingshot homolog 2 (Drosophila)
chr3_-_49823953 29.353 IP6K1
inositol hexakisphosphate kinase 1
chr5_-_19988293 29.211 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr8_+_80523304 29.192 STMN2
stathmin-like 2
chr4_+_166299942 28.938 NM_001873
CPE
carboxypeptidase E
chr22_-_19511777 28.886 CLDN5
claudin 5
chr12_+_113229548 28.590 NM_001143854
NM_014954
RPH3A

rabphilin 3A homolog (mouse)

chr22_+_50946627 27.684 NM_001185011
NM_014551
NM_152299
NCAPH2


non-SMC condensin II complex, subunit H2


chr4_-_176733413 27.509 GPM6A
glycoprotein M6A
chr2_-_71454200 27.469 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chrX_+_110187468 27.227 NM_001128166
NM_001128167
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chr17_+_28256873 26.854 NM_001145053
EFCAB5
EF-hand calcium binding domain 5
chr17_+_74734106 26.747 MFSD11
major facilitator superfamily domain containing 11
chr22_-_50523780 26.741 NM_139202
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_-_50523853 26.656 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr11_-_119294242 26.634 NM_006288
THY1
Thy-1 cell surface antigen
chr12_-_112819755 26.345 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chr6_+_126070813 26.093 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr22_-_19512001 26.064 CLDN5
claudin 5
chr22_-_50524357 25.147 NM_015166
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr2_+_46524901 24.493 EPAS1
endothelial PAS domain protein 1
chr2_+_242127923 24.434 NM_001001666
NM_001001891
ANO7

anoctamin 7

chr19_+_19030523 24.371 DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr14_+_100842728 24.348 NM_001161476
NM_024515
WDR25

WD repeat domain 25

chr6_+_41020939 24.344 NM_006789
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr2_-_176866925 24.077 NM_030650
KIAA1715
KIAA1715
chr2_+_46524448 24.034 NM_001430
EPAS1
endothelial PAS domain protein 1
chrX_-_72434656 23.859 NAP1L2
nucleosome assembly protein 1-like 2
chr1_+_151043079 23.838 NM_144618
GABPB2
GA binding protein transcription factor, beta subunit 2
chr6_+_73076431 23.807 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_183274008 23.756 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr19_+_40854529 23.618 PLD3
phospholipase D family, member 3
chr19_+_19030491 23.382 DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr10_-_61469322 23.300 NM_194298
LOC100129721
SLC16A9
uncharacterized LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr4_-_16228071 22.969 TAPT1
transmembrane anterior posterior transformation 1
chr3_-_49823972 22.312 NM_001006115
NM_153273
IP6K1

inositol hexakisphosphate kinase 1

chr2_-_37311458 22.200 NM_019024
HEATR5B
HEAT repeat containing 5B
chr10_+_124220990 22.088 NM_002775
HTRA1
HtrA serine peptidase 1
chr13_+_48877950 22.079 RB1
retinoblastoma 1
chr4_+_159690208 21.777 FNIP2
folliculin interacting protein 2
chr4_+_100871625 21.721 LOC256880
uncharacterized LOC256880
chr12_-_109027565 21.684 SELPLG
selectin P ligand
chr8_+_38243958 21.504 NM_001199659
NM_144652
LETM2

leucine zipper-EF-hand containing transmembrane protein 2

chr6_-_109415514 21.440 NM_014454
SESN1
sestrin 1
chr15_+_43809805 21.424 NM_002373
MAP1A
microtubule-associated protein 1A
chr10_-_90750955 21.383 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr19_+_51728369 21.314 CD33
CD33 molecule
chr16_+_85061303 21.150 NM_014732
KIAA0513
KIAA0513
chr2_+_97202463 20.987 NM_212481
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr19_+_41903718 20.795 BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr17_-_79869033 20.770 PCYT2
phosphate cytidylyltransferase 2, ethanolamine
chr11_+_12132063 20.638 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr19_-_14228560 20.585 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr7_-_42276617 20.512 NM_000168
GLI3
GLI family zinc finger 3
chr17_-_66951381 20.400 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr10_-_48438975 20.309 NM_004962
GDF10
growth differentiation factor 10
chr16_+_50776012 20.153 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr10_-_69597768 20.150 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr14_-_24584125 20.115 NRL
neural retina leucine zipper
chr1_-_54872075 20.101 NM_001009955
SSBP3
single stranded DNA binding protein 3
chr16_+_71392615 19.837 NM_001740
NM_007088
CALB2

calbindin 2

chr16_+_50775960 19.743 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr6_-_13487772 19.733 NM_001242629
NM_018988
GFOD1

glucose-fructose oxidoreductase domain containing 1

chr10_+_86004808 19.706 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr2_-_87017948 19.646 CD8A
CD8a molecule
chr6_-_41863086 19.626 NM_018561
USP49
ubiquitin specific peptidase 49
chr20_+_1246959 19.612 NM_014723
SNPH
syntaphilin
chr3_-_127541975 19.498 NM_001003794
MGLL
monoglyceride lipase
chr1_-_160681552 19.322 NM_001778
CD48
CD48 molecule
chr1_-_20141593 19.253 NM_019062
RNF186
ring finger protein 186
chr18_-_47807676 19.119 MBD1
methyl-CpG binding domain protein 1
chr16_+_71392637 19.063 CALB2
calbindin 2
chr19_-_14952688 18.971 NM_001005190
OR7A10
olfactory receptor, family 7, subfamily A, member 10
chr6_-_41130864 18.970 TREM2
triggering receptor expressed on myeloid cells 2
chr16_-_30582951 18.812 ZNF688
zinc finger protein 688
chr4_+_88896868 18.754 SPP1
secreted phosphoprotein 1
chr5_+_157170702 18.750 NM_173491
LSM11
LSM11, U7 small nuclear RNA associated
chr19_+_51728319 18.743 NM_001082618
NM_001177608
NM_001772
CD33


CD33 molecule


chr18_-_52969714 18.698 NM_001243236
TCF4
transcription factor 4
chr4_+_128886539 18.668 C4orf29
chromosome 4 open reading frame 29
chr2_+_64751545 18.652 AFTPH
aftiphilin
chr2_-_201936386 18.626 FAM126B
family with sequence similarity 126, member B
chr2_-_211179765 18.623 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr4_+_88896899 18.608 SPP1
secreted phosphoprotein 1
chr1_+_163038564 18.599 NM_005613
RGS4
regulator of G-protein signaling 4
chr7_+_97361270 18.598 NM_003182
NM_013996
NM_013997
NM_013998
TAC1



tachykinin, precursor 1



chr6_+_99282579 18.464 NM_005604
POU3F2
POU class 3 homeobox 2
chr19_+_4969123 18.385 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr10_-_99393851 18.367 NM_001098831
MORN4
MORN repeat containing 4
chr14_-_73360792 18.313 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr2_+_233925104 18.305 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr13_+_28494136 18.257 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr6_-_84418705 18.240 NM_001242792
SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr12_+_6898705 18.189 CD4
CD4 molecule
chr1_-_220445747 18.082 RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chrX_-_72434623 18.049 NAP1L2
nucleosome assembly protein 1-like 2
chr5_-_24645084 18.044 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr12_+_53442732 17.989 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr6_-_112194430 17.936 FYN
FYN oncogene related to SRC, FGR, YES
chr17_-_26220372 17.855 NM_001076680
C17orf108
chromosome 17 open reading frame 108
chr4_+_113970784 17.848 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr4_-_176923480 17.791 GPM6A
glycoprotein M6A
chr12_-_109027615 17.778 SELPLG
selectin P ligand
chr1_-_155532152 17.712 ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr19_+_40854331 17.642 NM_001031696
NM_012268
PLD3

phospholipase D family, member 3

chr4_-_176923533 17.571 GPM6A
glycoprotein M6A
chr1_-_54871978 17.556 NM_018070
NM_145716
SSBP3

single stranded DNA binding protein 3

chr16_-_30583727 17.532 NM_001024683
NM_145271
ZNF688

zinc finger protein 688

chr5_+_140868721 17.478 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr17_-_66287256 17.445 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr2_-_1926501 17.400 MYT1L
myelin transcription factor 1-like
chr14_-_106237675 17.384 IGHM
immunoglobulin heavy constant mu
chr17_+_3377346 17.290 NM_001128085
ASPA
aspartoacylase
chr6_-_112194648 17.283 NM_002037
FYN
FYN oncogene related to SRC, FGR, YES
chr4_+_88896801 17.258 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr1_+_100111430 17.150 NM_017734
PALMD
palmdelphin
chr17_-_56618178 17.139 NM_001198713
SEPT4
septin 4
chr15_+_42840991 17.129 NM_001130447
NM_018097
HAUS2

HAUS augmin-like complex, subunit 2

chr5_-_169724614 17.111 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr15_-_42840910 17.017 LRRC57
leucine rich repeat containing 57
chr2_+_233925035 16.908 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr12_+_119616594 16.855 NM_014365
HSPB8
heat shock 22kDa protein 8
chr3_-_52719514 16.786 NM_018313
PBRM1
polybromo 1
chr7_-_152132924 16.783 MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr1_-_54871681 16.755 SSBP3
single stranded DNA binding protein 3
chr3_-_128879873 16.681 NM_001204890
NM_001199469
NM_020701
ISY1-RAB43
ISY1

ISY1-RAB43 readthrough
ISY1 splicing factor homolog (S. cerevisiae)

chr3_-_101231973 16.468 NM_001077203
NM_020654
SENP7

SUMO1/sentrin specific peptidase 7

chr19_+_48972574 16.460 CYTH2
cytohesin 2
chr3_+_4535106 16.448 ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr10_+_115310589 16.277 NM_001177660
HABP2
hyaluronan binding protein 2
chr1_+_101702561 16.203 S1PR1
sphingosine-1-phosphate receptor 1
chr17_+_59477473 16.201 TBX2
T-box 2
chr12_-_109027654 16.109 NM_003006
SELPLG
selectin P ligand
chrX_-_48931645 16.082 NM_007213
PRAF2
PRA1 domain family, member 2
chrX_-_72434667 16.061 NM_021963
NAP1L2
nucleosome assembly protein 1-like 2
chr11_+_73661363 16.030 NM_153614
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr10_+_106034886 16.012 NM_001191014
NM_001191015
GSTO2

glutathione S-transferase omega 2

chr10_-_99393175 15.976 NM_178832
MORN4
MORN repeat containing 4
chr6_-_41130921 15.799 NM_018965
TREM2
triggering receptor expressed on myeloid cells 2
chr16_+_31366519 15.745 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr3_+_31574119 15.737 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr5_-_88199868 15.622 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr4_+_159593233 15.526 NM_004453
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr11_-_57004674 15.367 NM_005161
APLNR
apelin receptor
chr4_-_89205667 15.359 PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr1_+_101702304 15.355 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr12_-_48152860 15.304 NM_001098531
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr2_+_143886898 15.252 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr3_+_150264514 15.220 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr4_+_88896838 15.212 SPP1
secreted phosphoprotein 1
chr19_-_14228362 15.197 NM_002730
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr7_+_135347211 15.166 NM_001130929
SLC13A4
C7orf73
solute carrier family 13 (sodium/sulfate symporters), member 4
chromosome 7 open reading frame 73
chr17_+_68165660 15.134 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr15_-_23208356 15.049 WHAMMP3
WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 3
chr12_-_16759939 14.988 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_+_53497273 14.812 NM_003578
SOAT2
sterol O-acyltransferase 2
chrX_+_153775828 14.745 IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr8_-_67090690 14.742 NM_000756
CRH
corticotropin releasing hormone
chr19_-_38714781 14.739 NM_001135155
NM_004647
DPF1

D4, zinc and double PHD fingers family 1

chr2_-_188312872 14.715 NM_005795
CALCRL
calcitonin receptor-like
chr12_+_108909049 14.710 NM_007076
FICD
FIC domain containing
chr10_-_75255718 14.659 PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr12_-_91398744 14.629 EPYC
epiphycan
chr3_-_195306274 14.605 APOD
apolipoprotein D
chr1_+_156123321 14.577 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chrX_+_49644469 14.567 NM_001145073
USP27X
ubiquitin specific peptidase 27, X-linked
chr2_+_166152282 14.563 NM_001040143
SCN2A
sodium channel, voltage-gated, type II, alpha subunit

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.52 5.10e-15 GO:0023052 signaling
1.50 3.91e-12 GO:0007165 signal transduction
1.26 2.18e-11 GO:0065007 biological regulation
1.36 5.55e-11 GO:0032501 multicellular organismal process
1.26 1.10e-09 GO:0050789 regulation of biological process
1.39 3.09e-09 GO:0051716 cellular response to stimulus
1.26 5.05e-09 GO:0050794 regulation of cellular process
1.61 1.06e-07 GO:0007166 cell surface receptor linked signaling pathway
1.46 2.13e-07 GO:0048731 system development
1.26 3.13e-07 GO:0050896 response to stimulus
1.14 1.26e-06 GO:0009987 cellular process
1.38 2.71e-06 GO:0007275 multicellular organismal development
1.40 2.75e-06 GO:0048856 anatomical structure development
1.88 1.41e-05 GO:0007267 cell-cell signaling
1.33 2.28e-05 GO:0032502 developmental process
1.59 2.84e-05 GO:0007399 nervous system development
1.63 3.12e-05 GO:0051239 regulation of multicellular organismal process
1.46 6.57e-05 GO:0065008 regulation of biological quality
1.62 1.21e-04 GO:0002376 immune system process
1.32 2.35e-04 GO:0051179 localization
1.46 4.89e-04 GO:0048583 regulation of response to stimulus
1.77 6.01e-04 GO:2000026 regulation of multicellular organismal development
1.40 8.11e-04 GO:0042221 response to chemical stimulus
1.79 9.09e-04 GO:0002682 regulation of immune system process
2.70 9.80e-04 GO:0051251 positive regulation of lymphocyte activation
1.64 1.22e-03 GO:0007154 cell communication
2.60 1.59e-03 GO:0002696 positive regulation of leukocyte activation
2.56 2.34e-03 GO:0050867 positive regulation of cell activation
1.47 2.48e-03 GO:0023051 regulation of signaling
2.13 2.77e-03 GO:0044057 regulation of system process
2.58 2.89e-03 GO:0003012 muscle system process
1.97 3.10e-03 GO:0007268 synaptic transmission
1.64 4.13e-03 GO:0050793 regulation of developmental process
1.44 4.62e-03 GO:0003008 system process
2.78 5.07e-03 GO:0050870 positive regulation of T cell activation
1.50 5.42e-03 GO:0035556 intracellular signal transduction
1.88 5.77e-03 GO:0019226 transmission of nerve impulse
1.88 5.77e-03 GO:0035637 multicellular organismal signaling
1.93 6.23e-03 GO:0002684 positive regulation of immune system process
1.37 1.18e-02 GO:0048523 negative regulation of cellular process
2.53 1.33e-02 GO:0006936 muscle contraction
1.89 1.44e-02 GO:0051094 positive regulation of developmental process
1.32 1.47e-02 GO:0048518 positive regulation of biological process
1.45 1.49e-02 GO:0009653 anatomical structure morphogenesis
3.08 1.52e-02 GO:0050851 antigen receptor-mediated signaling pathway
1.70 1.61e-02 GO:0045595 regulation of cell differentiation
1.39 1.66e-02 GO:0048513 organ development
1.46 1.73e-02 GO:0009966 regulation of signal transduction
1.30 1.93e-02 GO:0051234 establishment of localization
1.75 3.21e-02 GO:0050878 regulation of body fluid levels
2.00 3.27e-02 GO:0045597 positive regulation of cell differentiation
1.86 4.22e-02 GO:0060341 regulation of cellular localization
1.56 4.92e-02 GO:0009611 response to wounding

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.70 5.24e-15 GO:0044459 plasma membrane part
1.42 2.71e-12 GO:0005886 plasma membrane
1.41 3.37e-12 GO:0071944 cell periphery
1.83 5.25e-11 GO:0031226 intrinsic to plasma membrane
1.80 4.54e-10 GO:0005887 integral to plasma membrane
2.27 3.22e-03 GO:0034702 ion channel complex
1.15 3.24e-03 GO:0016020 membrane
1.59 3.65e-03 GO:0005626 insoluble fraction
1.50 4.44e-03 GO:0000267 cell fraction
1.88 7.15e-03 GO:0009986 cell surface
1.55 1.69e-02 GO:0005624 membrane fraction
3.44 2.60e-02 GO:0034707 chloride channel complex
2.38 3.32e-02 GO:0009897 external side of plasma membrane
1.31 3.66e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.08 6.00e-05 GO:0015267 channel activity
2.07 6.55e-05 GO:0022803 passive transmembrane transporter activity
2.00 6.18e-04 GO:0022838 substrate-specific channel activity
1.61 9.87e-04 GO:0022857 transmembrane transporter activity
1.95 1.90e-03 GO:0005216 ion channel activity
1.16 2.22e-03 GO:0005515 protein binding
1.49 5.69e-03 GO:0005215 transporter activity
1.09 8.55e-03 GO:0005488 binding
1.51 1.21e-02 GO:0005102 receptor binding
1.51 1.49e-02 GO:0022892 substrate-specific transporter activity
1.60 1.53e-02 GO:0015075 ion transmembrane transporter activity
1.64 1.59e-02 GO:0005509 calcium ion binding
1.95 2.17e-02 GO:0022836 gated channel activity