Motif ID: TGIF1.p2

Z-value: 3.172


Transcription factors associated with TGIF1.p2:

Gene SymbolEntrez IDGene Name
TGIF1 7050 TGFB-induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TGIF1chr18_+_3447607-0.812.9e-51Click!


Activity profile for motif TGIF1.p2.

activity profile for motif TGIF1.p2


Sorted Z-values histogram for motif TGIF1.p2

Sorted Z-values for motif TGIF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TGIF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_5248180 82.041 NM_000518
 HBB
hemoglobin, beta
chr8_+_80523048 65.290 NM_001199214
NM_007029
 STMN2

stathmin-like 2

chr12_-_9268513 59.342 A2M
alpha-2-macroglobulin
chr19_+_45409003 47.019 NM_000041
 APOE
apolipoprotein E
chr3_+_45067750 42.103 NM_003278
 CLEC3B
C-type lectin domain family 3, member B
chr12_-_9268475 41.329 A2M
alpha-2-macroglobulin
chr19_-_39390168 39.464 NM_012237
NM_001193286
NM_030593
 SIRT2


sirtuin 2


chr12_-_9268522 39.133 NM_000014
 A2M
alpha-2-macroglobulin
chr4_+_113739203 38.873 NM_001127493
 ANK2
ankyrin 2, neuronal
chr6_+_32407618 38.757 NM_019111
 HLA-DRA
major histocompatibility complex, class II, DR alpha
chr6_-_108145507 37.937 NM_198081
 SCML4
sex comb on midleg-like 4 (Drosophila)
chr1_-_11907741 37.835 NM_006172
 NPPA
natriuretic peptide A
chr14_+_100150596 37.816 NM_006668
 CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr12_-_9268440 37.686 A2M
alpha-2-macroglobulin
chr17_+_41857802 37.132 NM_001136483
 C17orf105
chromosome 17 open reading frame 105
chr10_-_73848263 36.306 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_+_30951414 35.752 NM_198098
 AQP1
aquaporin 1 (Colton blood group)
chr16_+_30710461 34.827 NM_006662
 SRCAP
Snf2-related CREBBP activator protein
chr3_+_35722428 34.583 NM_198399
 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr7_-_137028533 33.644 NM_002825
 PTN
pleiotrophin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
enrichment   p-value GO term description
3.08 1.52e-02 GO:0050851 antigen receptor-mediated signaling pathway
2.78 5.07e-03 GO:0050870 positive regulation of T cell activation
2.70 9.80e-04 GO:0051251 positive regulation of lymphocyte activation
2.60 1.59e-03 GO:0002696 positive regulation of leukocyte activation
2.58 2.89e-03 GO:0003012 muscle system process
2.56 2.34e-03 GO:0050867 positive regulation of cell activation
2.53 1.33e-02 GO:0006936 muscle contraction
2.13 2.77e-03 GO:0044057 regulation of system process
2.00 3.27e-02 GO:0045597 positive regulation of cell differentiation
1.97 3.10e-03 GO:0007268 synaptic transmission
1.93 6.23e-03 GO:0002684 positive regulation of immune system process
1.89 1.44e-02 GO:0051094 positive regulation of developmental process
1.88 1.41e-05 GO:0007267 cell-cell signaling
1.88 5.77e-03 GO:0019226 transmission of nerve impulse
1.88 5.77e-03 GO:0035637 multicellular organismal signaling
1.86 4.22e-02 GO:0060341 regulation of cellular localization
1.79 9.09e-04 GO:0002682 regulation of immune system process
1.77 6.01e-04 GO:2000026 regulation of multicellular organismal development
1.75 3.21e-02 GO:0050878 regulation of body fluid levels
1.70 1.61e-02 GO:0045595 regulation of cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
3.44 2.60e-02 GO:0034707 chloride channel complex
2.38 3.32e-02 GO:0009897 external side of plasma membrane
2.27 3.22e-03 GO:0034702 ion channel complex
1.88 7.15e-03 GO:0009986 cell surface
1.83 5.25e-11 GO:0031226 intrinsic to plasma membrane
1.80 4.54e-10 GO:0005887 integral to plasma membrane
1.70 5.24e-15 GO:0044459 plasma membrane part
1.59 3.65e-03 GO:0005626 insoluble fraction
1.55 1.69e-02 GO:0005624 membrane fraction
1.50 4.44e-03 GO:0000267 cell fraction
1.42 2.71e-12 GO:0005886 plasma membrane
1.41 3.37e-12 GO:0071944 cell periphery
1.31 3.66e-02 GO:0005576 extracellular region
1.15 3.24e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.08 6.00e-05 GO:0015267 channel activity
2.07 6.55e-05 GO:0022803 passive transmembrane transporter activity
2.00 6.18e-04 GO:0022838 substrate-specific channel activity
1.95 1.90e-03 GO:0005216 ion channel activity
1.95 2.17e-02 GO:0022836 gated channel activity
1.64 1.59e-02 GO:0005509 calcium ion binding
1.61 9.87e-04 GO:0022857 transmembrane transporter activity
1.60 1.53e-02 GO:0015075 ion transmembrane transporter activity
1.51 1.21e-02 GO:0005102 receptor binding
1.51 1.49e-02 GO:0022892 substrate-specific transporter activity
1.49 5.69e-03 GO:0005215 transporter activity
1.16 2.22e-03 GO:0005515 protein binding
1.09 8.55e-03 GO:0005488 binding