Motif ID: UAAGACU

Z-value: 0.642


Mature miRNA associated with seed UAAGACU:

NamemiRBase Accession
hsa-miR-499-5p MIMAT0002870



Activity profile for motif UAAGACU.

activity profile for motif UAAGACU


Sorted Z-values histogram for motif UAAGACU

Sorted Z-values for motif UAAGACU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAAGACU

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_86564632 13.987 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr2_-_86565205 13.368 NM_001164730
REEP1
receptor accessory protein 1
chr5_-_79286793 10.668 NM_001010891
NM_001167741
MTX3

metaxin 3

chr8_-_82359620 9.703 NM_002677
PMP2
peripheral myelin protein 2
chr13_-_44453825 9.145 NM_144974
CCDC122
coiled-coil domain containing 122
chr15_-_48470453 8.864 NM_016132
MYEF2
myelin expression factor 2
chr2_+_66662516 7.847 NM_002398
MEIS1
Meis homeobox 1
chr3_-_18480203 7.467 NM_001131010
SATB1
SATB homeobox 1
chr7_+_86781869 7.259 NM_021145
DMTF1
cyclin D binding myb-like transcription factor 1
chr3_-_18466759 7.232 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr7_-_17980102 7.158 NM_015132
SNX13
sorting nexin 13
chr12_-_42538432 7.059 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr7_+_86781644 6.679 NM_001142326
NM_001142327
DMTF1

cyclin D binding myb-like transcription factor 1

chr19_+_32836500 6.609 NM_001136156
NM_014910
ZNF507

zinc finger protein 507

chr8_+_58906968 6.604 NM_147189
FAM110B
family with sequence similarity 110, member B
chr6_+_72922513 6.512 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr7_+_138916230 6.437 NM_173569
UBN2
ubinuclein 2
chr5_+_161274196 6.251 NM_000806
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_161274684 5.768 NM_001127643
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_+_11561710 5.552 NM_002052
GATA4
GATA binding protein 4
chr12_-_93323088 5.510 NM_003566
EEA1
early endosome antigen 1
chr17_+_30813928 5.496 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr5_-_58334936 5.461 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr5_+_161275541 5.400 NM_001127645
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr17_-_29624249 5.365 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chrX_+_16737661 5.334 NM_032796
SYAP1
synapse associated protein 1
chr4_+_139936938 5.332 NM_012118
CCRN4L
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr4_-_87028805 5.271 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr9_-_23821842 5.075 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_-_45956795 5.072 NM_007170
TESK2
testis-specific kinase 2
chr6_+_72926144 4.800 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr8_+_38644721 4.671 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr2_+_210867321 4.584 NM_006916
RPE
ribulose-5-phosphate-3-epimerase
chr7_-_139876718 4.558 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr2_+_210867355 4.542 NM_199229
RPE
ribulose-5-phosphate-3-epimerase
chr2_-_200820458 4.539 NM_001039693
TYW5
tRNA-yW synthesizing protein 5
chr19_-_3700466 4.533 NM_001195733
NM_012398
PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

chr15_-_64648359 4.496 NM_022048
CSNK1G1
casein kinase 1, gamma 1
chr4_-_87374282 4.482 NM_002753
MAPK10
mitogen-activated protein kinase 10
chr8_+_42752019 4.441 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr5_+_161274939 4.399 NM_001127644
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr8_+_85095452 4.355 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chrX_+_68048792 4.343 NM_004429
EFNB1
ephrin-B1
chr8_+_85095501 4.299 NM_173848
RALYL
RALY RNA binding protein-like
chr19_+_37997840 4.209 NM_001013659
ZNF793
zinc finger protein 793
chr6_+_73076431 4.128 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr4_-_176734181 4.049 NM_201591
GPM6A
glycoprotein M6A
chr6_-_52860076 4.029 NM_001512
GSTA4
glutathione S-transferase alpha 4
chr8_+_85097099 3.931 NM_001100391
RALYL
RALY RNA binding protein-like
chr9_+_82186846 3.854 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr15_-_45815001 3.848 NM_013309
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr9_-_23821477 3.845 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_-_120548329 3.833 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr8_+_38585703 3.726 NM_001146216
TACC1
transforming, acidic coiled-coil containing protein 1
chr1_+_26438267 3.710 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr12_+_32654976 3.702 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr17_+_29718641 3.565 NM_032932
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr5_+_112043188 3.561 NM_001127511
APC
adenomatous polyposis coli
chr1_+_97187174 3.542 NM_021190
PTBP2
polypyrimidine tract binding protein 2
chr4_-_87281374 3.512 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr5_+_161277391 3.497 NM_001127647
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr14_+_29236171 3.491 NM_005249
FOXG1
forkhead box G1
chr3_-_15374082 3.471 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr1_-_92371558 3.467 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr6_+_72926462 3.466 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr9_-_23826062 3.458 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_-_128392061 3.368 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr5_-_58652671 3.347 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_176923572 3.295 NM_005277
NM_201592
GPM6A

glycoprotein M6A

chrY_+_15016698 3.259 NM_004660
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr15_-_83953465 3.252 NM_001717
BNC1
basonuclin 1
chr13_-_107220444 3.156 NM_018011
ARGLU1
arginine and glutamate rich 1
chr16_+_55542909 3.152 NM_017839
LPCAT2
lysophosphatidylcholine acyltransferase 2
chr3_+_186501360 3.052 NM_001967
EIF4A2
eukaryotic translation initiation factor 4A2
chr18_-_74207145 3.039 NM_014643
ZNF516
zinc finger protein 516
chr6_+_126240369 3.034 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr5_-_58295758 3.009 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_+_72596648 2.950 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chrX_-_34675366 2.914 NM_031442
TMEM47
transmembrane protein 47
chr6_+_126111782 2.911 NM_001122842
NM_001199621
NM_181782
NCOA7


nuclear receptor coactivator 7


chr6_+_126102278 2.817 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr15_+_101142754 2.693 NM_024708
NM_198243
ASB7

ankyrin repeat and SOCS box containing 7

chr14_+_105780751 2.663 NM_001100913
NM_015197
PACS2

phosphofurin acidic cluster sorting protein 2

chr14_-_50698090 2.627 NM_006939
SOS2
son of sevenless homolog 2 (Drosophila)
chr7_-_120498128 2.615 NM_012338
TSPAN12
tetraspanin 12
chr5_+_112073555 2.612 NM_000038
NM_001127510
APC

adenomatous polyposis coli

chr1_-_92351613 2.592 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr10_-_35930357 2.568 NM_031866
FZD8
frizzled family receptor 8
chr12_+_122459791 2.560 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr11_-_70507911 2.543 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr4_-_120549115 2.529 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr16_+_1756161 2.454 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr1_+_145438437 2.446 NM_006472
TXNIP
thioredoxin interacting protein
chr21_-_19191643 2.444 NM_001100420
NM_001100421
NM_017447
C21orf91


chromosome 21 open reading frame 91


chr2_+_48541767 2.421 NM_002158
FOXN2
forkhead box N2
chrY_+_15016018 2.412 NM_001122665
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr6_+_39760148 2.406 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr1_-_147232684 2.402 NM_181703
GJA5
gap junction protein, alpha 5, 40kDa
chr5_+_161275897 2.396 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_-_59064437 2.388 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_+_161277702 2.383 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr12_-_26277807 2.359 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr13_-_78549663 2.356 NM_000115
EDNRB
endothelin receptor type B
chr4_+_56212381 2.325 NM_024592
SRD5A3
steroid 5 alpha-reductase 3
chr15_-_49338496 2.285 NM_001193489
NM_014701
SECISBP2L

SECIS binding protein 2-like

chr3_-_15382874 2.260 NM_001018009
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr11_-_10829519 2.226 NM_001172705
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chrX_-_112066353 2.216 NM_001113490
AMOT
angiomotin
chr8_-_67579446 2.194 NM_025054
VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr18_-_25757351 2.164 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr22_+_29876180 2.130 NM_021076
NEFH
neurofilament, heavy polypeptide
chr6_+_133562488 2.042 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr3_+_14989076 2.016 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr4_+_156680125 1.931 NM_000857
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr2_-_109605668 1.904 NM_022336
EDAR
ectodysplasin A receptor
chr3_-_51533996 1.896 NM_001171904
NM_014703
VPRBP

Vpr (HIV-1) binding protein

chr16_+_54965110 1.890 NM_001252197
NM_005853
IRX5

iroquois homeobox 5

chr3_+_29322802 1.864 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr7_-_44924946 1.831 NM_033224
PURB
purine-rich element binding protein B
chr7_+_107384278 1.824 NM_024814
CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr17_+_26369617 1.733 NM_016231
NLK
nemo-like kinase
chr1_+_154300275 1.709 NM_020452
ATP8B2
ATPase, class I, type 8B, member 2
chr13_+_49549953 1.707 NM_001079673
FNDC3A
fibronectin type III domain containing 3A
chr9_+_101867401 1.701 NM_001130916
NM_004612
TGFBR1

transforming growth factor, beta receptor 1

chr22_-_46933066 1.669 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr10_+_74451838 1.646 NM_138357
MCU
mitochondrial calcium uniporter
chr4_+_37455551 1.641 NM_001104629
C4orf19
chromosome 4 open reading frame 19
chrX_-_112084006 1.632 NM_133265
AMOT
angiomotin
chr11_-_86666211 1.618 NM_012193
FZD4
frizzled family receptor 4
chr6_+_39760772 1.568 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr11_-_123525300 1.555 NM_001040151
NM_018400
SCN3B

sodium channel, voltage-gated, type III, beta

chr2_+_176981491 1.548 NM_002148
HOXD10
homeobox D10
chr6_+_37225506 1.513 NM_017772
TBC1D22B
TBC1 domain family, member 22B
chr18_-_57364643 1.480 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr11_-_70935807 1.418 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chrX_+_30671456 1.400 NM_000167
NM_001128127
NM_001205019
NM_203391
GK



glycerol kinase



chrX_+_21392396 1.385 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr11_-_128457452 1.381 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr8_-_29120571 1.327 NM_015254
KIF13B
kinesin family member 13B
chr11_-_85376159 1.321 NM_001039618
CREBZF
CREB/ATF bZIP transcription factor
chr6_+_37137882 1.294 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr2_-_69870976 1.270 NM_014911
AAK1
AP2 associated kinase 1
chr4_-_120549827 1.268 NM_001083
PDE5A
phosphodiesterase 5A, cGMP-specific
chr8_+_67976561 1.256 NM_024790
CSPP1
centrosome and spindle pole associated protein 1
chr11_+_111848008 1.213 NM_033425
DIXDC1
DIX domain containing 1
chr1_+_19923457 1.187 NM_001204088
NM_001204089
NM_001032363
NM_001204082
NM_001204083
C1orf151-NBL1

MINOS1


C1orf151-NBL1 readthrough

mitochondrial inner membrane organizing system 1


chr16_+_1664640 1.167 NM_020825
CRAMP1L
Crm, cramped-like (Drosophila)
chr13_-_78493902 1.136 NM_001201397
EDNRB
endothelin receptor type B
chr16_-_4897265 1.084 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chrX_-_154114431 1.067 NM_019863
F8
coagulation factor VIII, procoagulant component
chr19_-_6459735 1.055 NM_024103
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr5_-_59189620 1.047 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_37034609 1.031 NM_014805
EPM2AIP1
EPM2A (laforin) interacting protein 1
chr1_-_147245483 1.025 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr9_-_123476578 1.003 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr8_+_75262616 0.972 NM_018972
NM_001040875
GDAP1

ganglioside-induced differentiation-associated protein 1

chr14_+_103800492 0.965 NM_001969
EIF5
eukaryotic translation initiation factor 5
chr21_+_34697197 0.960 NM_000629
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr2_+_42396392 0.947 NM_001145076
NM_019063
EML4

echinoderm microtubule associated protein like 4

chr5_-_107006585 0.947 NM_001962
EFNA5
ephrin-A5
chr2_+_204192915 0.934 NM_005759
ABI2
abl-interactor 2
chr13_-_78492906 0.888 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr2_-_201936389 0.878 NM_173822
FAM126B
family with sequence similarity 126, member B
chr8_+_79428335 0.831 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr11_-_129872719 0.798 NM_020228
NM_199437
PRDM10

PR domain containing 10

chr12_-_12419702 0.754 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr7_+_90338711 0.745 NM_012395
CDK14
cyclin-dependent kinase 14
chr1_-_226128872 0.745 NM_001172425
NM_003240
LEFTY2

left-right determination factor 2

chr20_-_32274154 0.717 NM_005225
E2F1
E2F transcription factor 1
chr2_-_214016332 0.704 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr15_-_34502269 0.687 NM_024713
C15orf29
chromosome 15 open reading frame 29
chr2_+_226265601 0.679 NM_020864
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr19_+_10764896 0.635 NM_001137673
NM_004516
NM_012218
NM_017620
NM_153464
ILF3




interleukin enhancer binding factor 3, 90kDa




chr11_-_118047336 0.614 NM_004588
SCN2B
sodium channel, voltage-gated, type II, beta
chrX_-_154250769 0.610 NM_000132
F8
coagulation factor VIII, procoagulant component
chr1_+_100598705 0.602 NM_019083
CCDC76
coiled-coil domain containing 76
chr14_-_61115906 0.580 NM_005982
SIX1
SIX homeobox 1
chr17_-_62050200 0.574 NM_000334
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr2_+_239229140 0.544 NM_001139490
NM_015650
TRAF3IP1

TNF receptor-associated factor 3 interacting protein 1

chr5_-_58882274 0.526 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_58571916 0.523 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_-_36531767 0.497 NM_004620
NM_145803
TRAF6

TNF receptor-associated factor 6

chr2_+_32288579 0.485 NM_014946
NM_199436
SPAST

spastin

chr3_+_61547179 0.484 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr3_-_15563160 0.476 NM_005677
NM_080539
COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chr1_-_209979388 0.450 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr12_+_99038918 0.405 NM_001160
NM_013229
NM_181861
NM_181868
NM_181869
APAF1




apoptotic peptidase activating factor 1




chr6_+_3118861 0.404 NM_004332
BPHL
biphenyl hydrolase-like (serine hydrolase)
chr3_+_89156673 0.403 NM_005233
NM_182644
EPHA3

EPH receptor A3

chr6_+_42123143 0.372 NM_000409
GUCA1A
guanylate cyclase activator 1A (retina)
chr6_+_83777361 0.370 NM_001199942
NM_015018
DOPEY1

dopey family member 1

chr13_+_49684388 0.305 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr6_-_13711643 0.275 NM_005493
RANBP9
RAN binding protein 9
chr19_-_7293876 0.254 NM_000208
NM_001079817
INSR

insulin receptor

chr2_+_228029280 0.234 NM_000091
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr1_-_21113160 0.226 NM_016287
HP1BP3
heterochromatin protein 1, binding protein 3
chr3_-_15540378 0.212 NM_080538
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr11_+_111807857 0.201 NM_001037954
DIXDC1
DIX domain containing 1
chr3_-_56717132 0.199 NM_001112736
FAM208A
family with sequence similarity 208, member A
chr21_-_39870303 0.157 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.91 1.61e-05 GO:0007399 nervous system development
2.16 9.89e-05 GO:0048731 system development
3.41 1.10e-04 GO:0022008 neurogenesis
3.47 1.56e-04 GO:0048699 generation of neurons
2.71 2.41e-04 GO:0009653 anatomical structure morphogenesis
1.96 3.38e-04 GO:0007275 multicellular organismal development
2.02 3.62e-04 GO:0048856 anatomical structure development
2.30 1.17e-03 GO:0030154 cell differentiation
2.35 1.56e-03 GO:0048513 organ development
2.23 2.24e-03 GO:0048869 cellular developmental process
3.27 4.77e-03 GO:2000026 regulation of multicellular organismal development
1.79 6.25e-03 GO:0032502 developmental process
7.07 1.57e-02 GO:0016055 Wnt receptor signaling pathway
1.58 1.97e-02 GO:0032501 multicellular organismal process
2.82 2.33e-02 GO:0048468 cell development
3.16 2.40e-02 GO:0030182 neuron differentiation
13.24 3.10e-02 GO:0060041 retina development in camera-type eye
2.86 3.14e-02 GO:0040011 locomotion
2.17 3.36e-02 GO:0007166 cell surface receptor linked signaling pathway

Nothing significant found in compartment category.

Nothing significant found in function category.