Motif ID: UAAUGCU

Z-value: 0.922


Mature miRNA associated with seed UAAUGCU:

NamemiRBase Accession
hsa-miR-155 MIMAT0000646



Activity profile for motif UAAUGCU.

activity profile for motif UAAUGCU


Sorted Z-values histogram for motif UAAUGCU

Sorted Z-values for motif UAAUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAAUGCU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_69004614 11.735 NM_001010942
NM_001251917
NM_001251918
NM_001251921
NM_001251922
NM_015646
 RAP1B





RAP1B, member of RAS oncogene family





chr20_+_48807119 11.028 NM_005194
 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chrX_-_73834460 9.848 NM_016120
NM_183353
 RLIM

ring finger protein, LIM domain interacting

chr4_+_38665587 9.099 NM_016531
 KLF3
Kruppel-like factor 3 (basic)
chr3_-_141747434 8.609 NM_001178141
NM_001178142
NM_006286
 TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr14_+_75745480 8.515 NM_005252
 FOS
FBJ murine osteosarcoma viral oncogene homolog
chr6_+_7107986 8.451 NM_001003698
NM_001003699
NM_001003700
 RREB1


ras responsive element binding protein 1


chr20_-_39317875 8.254 NM_005461
 MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_-_202777545 7.991 NM_006618
 KDM5B
lysine (K)-specific demethylase 5B
chr3_-_141868208 7.630 NM_001178138
NM_001178139
 TFDP2

transcription factor Dp-2 (E2F dimerization partner 2)

chr19_+_39897457 7.541 NM_003407
 ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr3_-_123339423 7.375 NM_053031
NM_053032
 MYLK

myosin light chain kinase

chr12_-_15038724 7.103 NM_000900
NM_001190839
 MGP

matrix Gla protein

chr10_+_104535887 7.066 NM_017787
 C10orf26
chromosome 10 open reading frame 26
chr3_-_141719188 6.986 NM_001178140
 TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr17_-_47439326 6.941 NM_001145365
NM_014897
 ZNF652

zinc finger protein 652

chr7_-_139876718 6.895 NM_030647
 JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr15_+_96869156 6.847 NM_001145155
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr10_-_120514669 6.215 NM_153810
 C10orf46
chromosome 10 open reading frame 46
chr2_-_64881040 6.183 NM_014755
 SERTAD2
SERTA domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 102 entries
enrichment   p-value GO term description
21.51 2.64e-03 GO:0032925 regulation of activin receptor signaling pathway
15.98 1.76e-03 GO:0045646 regulation of erythrocyte differentiation
11.57 1.37e-02 GO:0045669 positive regulation of osteoblast differentiation
7.99 2.23e-03 GO:0007179 transforming growth factor beta receptor signaling pathway
5.86 3.71e-03 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
4.25 1.69e-02 GO:0002757 immune response-activating signal transduction
4.16 2.17e-02 GO:0002764 immune response-regulating signaling pathway
3.68 4.09e-02 GO:0002253 activation of immune response
3.38 9.40e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.34 3.69e-02 GO:0001944 vasculature development
3.29 2.89e-06 GO:0045893 positive regulation of transcription, DNA-dependent
3.24 2.30e-06 GO:0007167 enzyme linked receptor protein signaling pathway
3.19 7.03e-09 GO:0006351 transcription, DNA-dependent
3.17 1.43e-02 GO:0016568 chromatin modification
3.06 1.64e-05 GO:0051254 positive regulation of RNA metabolic process
3.03 2.08e-05 GO:0010628 positive regulation of gene expression
3.00 4.12e-03 GO:0006325 chromatin organization
2.99 4.45e-03 GO:0072358 cardiovascular system development
2.99 4.45e-03 GO:0072359 circulatory system development
2.89 3.08e-03 GO:0045892 negative regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
7.99 1.35e-03 GO:0016605 PML body
3.32 3.49e-02 GO:0016604 nuclear body
3.22 2.71e-02 GO:0005667 transcription factor complex
2.89 4.03e-06 GO:0044451 nucleoplasm part
2.60 4.84e-09 GO:0005654 nucleoplasm
2.28 1.01e-08 GO:0031981 nuclear lumen
2.16 7.97e-09 GO:0044428 nuclear part
1.95 1.80e-06 GO:0043233 organelle lumen
1.94 4.18e-06 GO:0070013 intracellular organelle lumen
1.92 3.63e-06 GO:0031974 membrane-enclosed lumen
1.63 6.60e-10 GO:0005634 nucleus
1.51 3.07e-02 GO:0043234 protein complex
1.45 3.30e-02 GO:0032991 macromolecular complex
1.27 1.03e-03 GO:0043231 intracellular membrane-bounded organelle
1.26 1.12e-03 GO:0043227 membrane-bounded organelle
1.22 5.72e-03 GO:0043229 intracellular organelle
1.21 1.08e-04 GO:0044424 intracellular part
1.21 6.59e-03 GO:0043226 organelle
1.18 9.76e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
41.94 6.26e-03 GO:0004897 ciliary neurotrophic factor receptor activity
33.55 1.54e-02 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
15.98 2.45e-02 GO:0070491 repressing transcription factor binding
8.70 3.92e-03 GO:0046332 SMAD binding
7.99 6.98e-03 GO:0004702 receptor signaling protein serine/threonine kinase activity
6.15 4.93e-04 GO:0005057 receptor signaling protein activity
5.75 9.65e-04 GO:0019838 growth factor binding
5.67 2.35e-02 GO:0031625 ubiquitin protein ligase binding
3.52 1.22e-03 GO:0008134 transcription factor binding
3.09 1.22e-02 GO:0016563 transcription activator activity
3.07 1.92e-10 GO:0001071 nucleic acid binding transcription factor activity
3.07 1.92e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
2.67 2.04e-02 GO:0004674 protein serine/threonine kinase activity
2.61 4.99e-04 GO:0043565 sequence-specific DNA binding
2.41 4.76e-05 GO:0030528 transcription regulator activity
2.31 3.79e-02 GO:0004672 protein kinase activity
2.21 2.22e-02 GO:0019899 enzyme binding
1.90 7.53e-06 GO:0003677 DNA binding
1.68 2.93e-05 GO:0003676 nucleic acid binding
1.45 6.98e-08 GO:0005515 protein binding