Motif ID: UCACAUU

Z-value: 1.609


Mature miRNA associated with seed UCACAUU:

NamemiRBase Accession
hsa-miR-23a MIMAT0000078
hsa-miR-23b MIMAT0000418
hsa-miR-23c MIMAT0018000



Activity profile for motif UCACAUU.

activity profile for motif UCACAUU


Sorted Z-values histogram for motif UCACAUU

Sorted Z-values for motif UCACAUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_174254730 62.280 NM_001130689
 HMGB2
high mobility group box 2
chr12_+_104680712 51.728 NM_003330
NM_182729
NM_182742
NM_182743
 TXNRD1



thioredoxin reductase 1



chr12_+_104609501 47.406 NM_001093771
 TXNRD1
thioredoxin reductase 1
chr4_-_174255454 45.999 NM_001130688
NM_002129
 HMGB2

high mobility group box 2

chr17_-_29151724 34.173 NM_015986
 CRLF3
cytokine receptor-like factor 3
chr5_+_162864571 32.207 NM_004060
NM_199246
 CCNG1

cyclin G1

chr5_+_34687663 31.174 NM_001145523
 RAI14
retinoic acid induced 14
chr1_-_32385258 30.426 NM_001195100
NM_001195101
 PTP4A2

protein tyrosine phosphatase type IVA, member 2

chr14_+_73525187 27.730 NM_021239
 RBM25
RNA binding motif protein 25
chr13_+_98605928 27.566 NM_002271
 IPO5
importin 5
chr1_+_236557643 26.538 NM_145861
 EDARADD
EDAR-associated death domain
chr6_+_119215240 26.343 NM_014034
 ASF1A
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr1_-_32403975 26.340 NM_080391
 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr2_+_102314162 26.066 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
 MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr8_-_28243941 25.662 NM_018660
 ZNF395
zinc finger protein 395
chr3_-_113465101 24.692 NM_025146
 NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr4_+_41937105 24.556 NM_018126
 TMEM33
transmembrane protein 33
chr5_+_34684611 24.218 NM_001145521
NM_001145525
 RAI14

retinoic acid induced 14

chr20_+_39657461 23.263 NM_003286
 TOP1
topoisomerase (DNA) I
chr20_+_31407696 23.036 NM_012325
 MAPRE1
microtubule-associated protein, RP/EB family, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
4.28 1.73e-02 GO:0006470 protein dephosphorylation
3.88 4.98e-02 GO:0016311 dephosphorylation
2.72 3.74e-02 GO:0016568 chromatin modification
2.61 9.40e-03 GO:0006325 chromatin organization
2.60 3.31e-02 GO:0007243 intracellular protein kinase cascade
2.60 3.31e-02 GO:0023014 signal transduction via phosphorylation event
2.38 9.17e-03 GO:0051276 chromosome organization
2.28 7.34e-05 GO:0006793 phosphorus metabolic process
2.28 7.34e-05 GO:0006796 phosphate metabolic process
2.04 5.68e-07 GO:0006464 protein modification process
1.99 1.29e-06 GO:0043412 macromolecule modification
1.96 8.77e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.87 1.97e-02 GO:0009893 positive regulation of metabolic process
1.77 6.05e-03 GO:0016070 RNA metabolic process
1.76 1.55e-12 GO:0044260 cellular macromolecule metabolic process
1.75 2.20e-02 GO:0006996 organelle organization
1.72 9.14e-04 GO:0090304 nucleic acid metabolic process
1.65 6.96e-11 GO:0043170 macromolecule metabolic process
1.63 7.72e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 1.11e-04 GO:0006807 nitrogen compound metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
8.10 1.22e-03 GO:0008287 protein serine/threonine phosphatase complex
3.41 1.56e-03 GO:0016604 nuclear body
2.97 4.43e-02 GO:0000228 nuclear chromosome
2.83 4.74e-02 GO:0005635 nuclear envelope
2.33 7.83e-09 GO:0005654 nucleoplasm
2.22 1.90e-02 GO:0005694 chromosome
2.21 2.09e-03 GO:0044451 nucleoplasm part
2.13 1.72e-09 GO:0031981 nuclear lumen
2.12 2.04e-11 GO:0044428 nuclear part
1.92 4.15e-08 GO:0070013 intracellular organelle lumen
1.88 1.23e-07 GO:0043233 organelle lumen
1.85 2.95e-07 GO:0031974 membrane-enclosed lumen
1.59 4.01e-12 GO:0005634 nucleus
1.37 1.60e-11 GO:0043231 intracellular membrane-bounded organelle
1.37 1.89e-11 GO:0043227 membrane-bounded organelle
1.37 2.09e-04 GO:0044446 intracellular organelle part
1.36 3.41e-04 GO:0044422 organelle part
1.32 5.74e-07 GO:0005737 cytoplasm
1.31 9.27e-10 GO:0043229 intracellular organelle
1.31 1.21e-09 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
6.60 2.80e-02 GO:0004722 protein serine/threonine phosphatase activity
3.68 1.05e-02 GO:0004721 phosphoprotein phosphatase activity
2.48 1.16e-02 GO:0004674 protein serine/threonine kinase activity
2.22 1.19e-02 GO:0004672 protein kinase activity
2.04 2.53e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.99 4.05e-02 GO:0019899 enzyme binding
1.96 4.55e-02 GO:0016301 kinase activity
1.69 2.19e-02 GO:0005524 ATP binding
1.66 3.33e-02 GO:0032559 adenyl ribonucleotide binding
1.65 3.86e-02 GO:0030554 adenyl nucleotide binding
1.52 3.39e-02 GO:0000166 nucleotide binding
1.49 3.76e-13 GO:0005515 protein binding
1.41 4.08e-02 GO:0003676 nucleic acid binding
1.24 1.92e-11 GO:0005488 binding