Motif ID: UGUGCUU

Z-value: 2.410


Mature miRNA associated with seed UGUGCUU:

NamemiRBase Accession
hsa-miR-218 MIMAT0000275



Activity profile for motif UGUGCUU.

activity profile for motif UGUGCUU


Sorted Z-values histogram for motif UGUGCUU

Sorted Z-values for motif UGUGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UGUGCUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_130374466 62.415 NM_001032221
NM_003165
 STXBP1

syntaxin binding protein 1

chr16_+_58498725 58.575 NM_022910
 NDRG4
NDRG family member 4
chr16_+_58534045 56.708 NM_001242833
NM_001242834
NM_001242835
NM_001242836
 NDRG4



NDRG family member 4



chr16_+_58497993 52.823 NM_001130487
 NDRG4
NDRG family member 4
chr15_+_74422589 50.192 NM_001130138
 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr16_+_58497548 49.456 NM_020465
 NDRG4
NDRG family member 4
chr12_-_16760935 47.920 NM_001001395
NM_001243609
 LMO3

LIM domain only 3 (rhombotin-like 2)

chr18_+_21594349 47.533 NM_001135993
NM_001243425
 TTC39C

tetratricopeptide repeat domain 39C

chr7_-_37393271 47.019 NM_001206482
 ELMO1
engulfment and cell motility 1
chr12_-_16759531 46.481 NM_018640
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr15_+_74422742 45.649 NM_020851
 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr15_+_74421698 45.602 NM_001130136
 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr14_+_92790151 45.456 NM_153646
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr15_+_74421986 45.389 NM_001130137
 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr4_+_158141735 43.780 NM_000826
NM_001083619
NM_001083620
 GRIA2


glutamate receptor, ionotropic, AMPA 2


chr1_-_149889362 43.063 NM_014849
 SV2A
synaptic vesicle glycoprotein 2A
chr9_-_93405066 41.364 NM_017594
 DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr5_-_176057324 41.186 NM_001001502
NM_003085
 SNCB

synuclein, beta

chr7_+_153584383 40.385 NM_001039350
 DPP6
dipeptidyl-peptidase 6
chr11_-_134281725 39.080 NM_018644
NM_054025
 B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 52 entries
enrichment   p-value GO term description
7.49 4.61e-02 GO:0071377 cellular response to glucagon stimulus
4.13 2.39e-02 GO:0019933 cAMP-mediated signaling
3.44 1.67e-08 GO:0007268 synaptic transmission
3.21 4.38e-08 GO:0019226 transmission of nerve impulse
3.21 4.38e-08 GO:0035637 multicellular organismal signaling
2.98 1.99e-06 GO:0031175 neuron projection development
2.95 1.84e-05 GO:0048812 neuron projection morphogenesis
2.91 3.88e-07 GO:0048666 neuron development
2.85 1.83e-04 GO:0007409 axonogenesis
2.84 1.30e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
2.79 6.36e-03 GO:0007411 axon guidance
2.72 6.46e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.71 1.08e-04 GO:0048858 cell projection morphogenesis
2.68 1.34e-04 GO:0032990 cell part morphogenesis
2.67 6.28e-07 GO:0030182 neuron differentiation
2.60 4.96e-07 GO:0007267 cell-cell signaling
2.60 1.49e-02 GO:0051056 regulation of small GTPase mediated signal transduction
2.57 8.17e-04 GO:0000904 cell morphogenesis involved in differentiation
2.56 2.88e-05 GO:0030030 cell projection organization
2.54 8.28e-15 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
6.48 2.32e-02 GO:0042734 presynaptic membrane
4.50 1.70e-03 GO:0019717 synaptosome
3.57 5.12e-07 GO:0044456 synapse part
3.55 1.17e-02 GO:0034703 cation channel complex
3.45 5.28e-09 GO:0045202 synapse
2.80 3.83e-02 GO:0034702 ion channel complex
2.42 7.70e-05 GO:0030054 cell junction
2.42 1.25e-03 GO:0000139 Golgi membrane
2.42 6.94e-03 GO:0043005 neuron projection
2.29 7.96e-04 GO:0044431 Golgi apparatus part
1.93 1.37e-03 GO:0005794 Golgi apparatus
1.73 4.26e-06 GO:0044459 plasma membrane part
1.72 1.18e-02 GO:0005887 integral to plasma membrane
1.69 1.99e-02 GO:0031226 intrinsic to plasma membrane
1.57 4.68e-02 GO:0005856 cytoskeleton
1.52 2.98e-07 GO:0005886 plasma membrane
1.50 9.27e-07 GO:0071944 cell periphery
1.32 2.90e-07 GO:0016020 membrane
1.26 5.55e-03 GO:0044425 membrane part
1.07 7.55e-03 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
9.52 4.87e-02 GO:0008601 protein phosphatase type 2A regulator activity
3.38 2.76e-02 GO:0022843 voltage-gated cation channel activity
3.01 4.22e-04 GO:0005083 small GTPase regulator activity
2.93 4.76e-02 GO:0005244 voltage-gated ion channel activity
2.93 4.76e-02 GO:0022832 voltage-gated channel activity
2.85 1.13e-03 GO:0022836 gated channel activity
2.73 1.32e-02 GO:0005261 cation channel activity
2.52 3.10e-03 GO:0005216 ion channel activity
2.49 2.65e-03 GO:0015267 channel activity
2.49 2.78e-03 GO:0022803 passive transmembrane transporter activity
2.48 4.15e-03 GO:0022838 substrate-specific channel activity
2.47 1.06e-03 GO:0030695 GTPase regulator activity
2.41 1.86e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.89 4.28e-02 GO:0015075 ion transmembrane transporter activity