Motif ID: UUGGCAA

Z-value: 0.946


Mature miRNA associated with seed UUGGCAA:

NamemiRBase Accession
hsa-miR-182 MIMAT0000259



Activity profile for motif UUGGCAA.

activity profile for motif UUGGCAA


Sorted Z-values histogram for motif UUGGCAA

Sorted Z-values for motif UUGGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGCAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_91537724 22.300 NM_003981
NM_199413
NM_199414
PRC1


protein regulator of cytokinesis 1


chr2_+_235860616 22.070 NM_014521
SH3BP4
SH3-domain binding protein 4
chr3_-_195808958 18.540 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr3_-_195808997 18.358 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr1_+_165796652 17.844 NM_012474
UCK2
uridine-cytidine kinase 2
chr2_+_109204904 16.878 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_+_180630054 16.777 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chrX_+_119737743 15.409 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr1_-_94703252 15.345 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chrX_+_119738542 15.344 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr2_+_109204745 15.089 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_109237679 14.955 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_48894755 14.597 NM_006801
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr14_+_56046796 14.245 NM_001079521
NM_001079522
NM_004986
NM_182926
KTN1



kinectin 1 (kinesin receptor)



chr11_+_844062 14.158 NM_001025234
TSPAN4
tetraspanin 4
chr2_+_109223600 13.879 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr18_-_812268 13.691 NM_005433
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr5_+_72112417 13.637 NM_002270
TNPO1
transportin 1
chr12_+_123237302 13.624 NM_003677
DENR
density-regulated protein
chr11_+_844445 13.509 NM_001025237
TSPAN4
tetraspanin 4
chr3_+_187943192 13.499 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_+_69812620 13.469 NM_001184967
MITF
microphthalmia-associated transcription factor
chr3_-_145879222 13.388 NM_000935
NM_182943
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr6_+_47445440 13.323 NM_012120
CD2AP
CD2-associated protein
chr9_+_110045516 13.291 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr1_+_167298280 13.196 NM_001198783
POU2F1
POU class 2 homeobox 1
chr5_-_133968463 12.811 NM_001033503
NM_016103
SAR1B

SAR1 homolog B (S. cerevisiae)

chr7_-_137686814 12.662 NM_001253775
NM_194071
CREB3L2

cAMP responsive element binding protein 3-like 2

chr3_+_187930720 12.661 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr15_-_55562483 12.646 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr19_-_33166057 12.237 NM_032139
ANKRD27
ankyrin repeat domain 27 (VPS9 domain)
chr3_+_69812961 12.217 NM_006722
MITF
microphthalmia-associated transcription factor
chr2_+_109271267 12.151 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_174828775 12.055 NM_001017371
SP3
Sp3 transcription factor
chr5_-_137878915 11.846 NM_004730
ETF1
eukaryotic translation termination factor 1
chr20_+_361272 11.709 NM_021158
TRIB3
tribbles homolog 3 (Drosophila)
chr2_-_158731622 11.479 NM_001105
ACVR1
activin A receptor, type I
chr7_-_47621741 11.420 NM_022748
TNS3
tensin 3
chr3_-_134093235 11.311 NM_016201
AMOTL2
angiomotin like 2
chr12_-_109125289 11.233 NM_014325
CORO1C
coronin, actin binding protein, 1C
chr5_+_72143929 11.222 NM_153188
TNPO1
transportin 1
chr11_+_842821 11.196 NM_001025238
NM_001025239
NM_003271
NM_001025235
NM_001025236
TSPAN4




tetraspanin 4




chr1_+_182992329 10.859 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr11_-_110167191 10.843 NM_002906
RDX
radixin
chr2_+_109150807 10.753 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr17_+_45727274 10.725 NM_002265
KPNB1
karyopherin (importin) beta 1
chr13_-_50367027 10.719 NM_002267
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr4_+_39699663 10.516 NM_001111112
NM_001111113
NM_005339
UBE2K


ubiquitin-conjugating enzyme E2K


chrX_+_12809473 10.502 NM_001039091
NM_002765
PRPS2

phosphoribosyl pyrophosphate synthetase 2

chr5_-_43557520 10.429 NM_183323
PAIP1
poly(A) binding protein interacting protein 1
chr3_+_69788562 10.385 NM_198159
MITF
microphthalmia-associated transcription factor
chr17_-_4851797 10.307 NM_005022
PFN1
profilin 1
chr2_-_151344145 10.291 NM_005168
RND3
Rho family GTPase 3
chr1_-_86043932 10.194 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr5_+_86564727 10.052 NM_022650
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr18_+_29078026 9.989 NM_001943
DSG2
desmoglein 2
chr1_-_55352920 9.971 NM_014762
DHCR24
24-dehydrocholesterol reductase
chr8_+_98656329 9.895 NM_178812
MTDH
metadherin
chr3_+_171757413 9.889 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr11_-_47664014 9.856 NM_014342
MTCH2
mitochondrial carrier 2
chr3_+_69915374 9.754 NM_198177
MITF
microphthalmia-associated transcription factor
chr3_+_187871473 9.434 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr15_-_55563091 9.378 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr1_-_155904186 9.361 NM_014949
KIAA0907
KIAA0907
chr21_-_34852282 9.218 NM_006134
TMEM50B
transmembrane protein 50B
chr5_+_137673702 9.197 NM_016605
FAM53C
family with sequence similarity 53, member C
chr12_-_31479120 9.182 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chrX_-_102942968 9.160 NM_001142419
NM_001142420
NM_001142421
NM_001142422
NM_001142427
NM_001142428
NM_001142431
NM_001142432
MORF4L2







mortality factor 4 like 2







chr1_-_27816676 9.103 NM_001201404
NM_006990
WASF2

WAS protein family, member 2

chr5_+_86564044 9.008 NM_002890
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr10_-_16859408 8.995 NM_012425
NM_152724
RSU1

Ras suppressor protein 1

chr2_+_201170795 8.983 NM_001100422
NM_001100424
NM_001100423
SPATS2L


spermatogenesis associated, serine-rich 2-like


chrX_-_153141398 8.942 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chr15_-_55581969 8.937 NM_183235
RAB27A
RAB27A, member RAS oncogene family
chr5_-_43557098 8.930 NM_006451
NM_182789
PAIP1

poly(A) binding protein interacting protein 1

chr2_-_174830429 8.928 NM_001172712
NM_003111
SP3

Sp3 transcription factor

chr8_-_80993009 8.893 NM_001025252
TPD52
tumor protein D52
chr7_-_131241321 8.853 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr5_+_137673223 8.845 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr3_+_133292404 8.819 NM_001134422
NM_017548
CDV3

CDV3 homolog (mouse)

chr2_+_208394615 8.785 NM_004379
NM_134442
CREB1

cAMP responsive element binding protein 1

chr19_-_8070468 8.777 NM_001419
ELAVL1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr11_-_47510518 8.666 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr1_+_230202928 8.552 NM_004481
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr17_+_66508525 8.515 NM_002734
NM_212472
PRKAR1A

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

chr10_+_82213892 8.513 NM_001128309
NM_030927
TSPAN14

tetraspanin 14

chr1_-_68962726 8.468 NM_001114120
NM_017779
DEPDC1

DEP domain containing 1

chr14_+_55518313 8.456 NM_144578
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr20_+_31407696 8.385 NM_012325
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr1_+_26606212 8.270 NM_031286
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr8_+_125486949 8.255 NM_007218
RNF139
ring finger protein 139
chr3_+_87276398 8.215 NM_001244644
NM_014043
CHMP2B

charged multivesicular body protein 2B

chr6_+_64281910 8.183 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chrX_+_146993450 8.179 NM_001185075
NM_001185076
NM_001185081
NM_001185082
NM_002024
FMR1




fragile X mental retardation 1




chr11_-_47516072 8.124 NM_198700
CELF1
CUGBP, Elav-like family member 1
chr6_-_79787939 8.108 NM_017934
PHIP
pleckstrin homology domain interacting protein
chr3_+_133293256 8.034 NM_001134423
CDV3
CDV3 homolog (mouse)
chr12_-_56652118 7.995 NM_173595
ANKRD52
ankyrin repeat domain 52
chr5_+_154092461 7.986 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr3_-_32023237 7.949 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr3_+_179370779 7.911 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr14_+_64680858 7.864 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr9_-_36276930 7.818 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr10_+_70883856 7.816 NM_001035260
NM_004896
VPS26A

vacuolar protein sorting 26 homolog A (S. pombe)

chr3_+_135741576 7.713 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr2_+_201170603 7.697 NM_015535
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr7_-_105925410 7.641 NM_005746
NAMPT
nicotinamide phosphoribosyltransferase
chr11_+_107879407 7.618 NM_003478
CUL5
cullin 5
chr3_+_171758289 7.501 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr7_+_66386129 7.483 NM_017994
C7orf42
chromosome 7 open reading frame 42
chr12_+_110906203 7.309 NM_013300
C12orf24
chromosome 12 open reading frame 24
chr20_+_9288446 7.216 NM_000933
PLCB4
phospholipase C, beta 4
chr14_+_64682671 7.178 NM_182910
SYNE2
spectrin repeat containing, nuclear envelope 2
chr8_+_110346549 7.167 NM_001193557
NM_020189
ENY2

enhancer of yellow 2 homolog (Drosophila)

chr14_-_89883306 7.137 NM_005197
FOXN3
forkhead box N3
chr17_-_41174431 7.117 NM_006373
VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr17_+_75446612 7.098 NM_001113496
SEPT9
septin 9
chr12_-_80307690 7.076 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr14_-_75643335 7.048 NM_006827
TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr14_+_103801160 7.046 NM_183004
EIF5
eukaryotic translation initiation factor 5
chr15_+_99192696 6.956 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr6_-_114292312 6.855 NM_001527
HDAC2
histone deacetylase 2
chr1_-_150669499 6.808 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr1_+_110546569 6.797 NM_001242675
NM_001242676
AHCYL1

adenosylhomocysteinase-like 1

chr2_-_158732341 6.734 NM_001111067
ACVR1
activin A receptor, type I
chr7_-_2281822 6.673 NM_013393
FTSJ2
FtsJ homolog 2 (E. coli)
chr17_+_66508098 6.609 NM_212471
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr7_+_17338182 6.589 NM_001621
AHR
aryl hydrocarbon receptor
chr20_+_9049660 6.546 NM_001172646
PLCB4
phospholipase C, beta 4
chr3_+_38206968 6.469 NM_005109
OXSR1
oxidative-stress responsive 1
chr8_+_56015013 6.409 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr12_-_76478737 6.395 NM_004537
NM_139207
NAP1L1

nucleosome assembly protein 1-like 1

chr1_+_89149836 6.268 NM_006256
PKN2
protein kinase N2
chr1_+_7831326 6.258 NM_004781
VAMP3
vesicle-associated membrane protein 3 (cellubrevin)
chr19_-_10514242 6.248 NM_007065
CDC37
cell division cycle 37 homolog (S. cerevisiae)
chr1_-_85930733 6.242 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr10_+_51576284 6.239 NM_001145262
NCOA4
nuclear receptor coactivator 4
chr17_-_37607314 6.195 NM_004774
MED1
mediator complex subunit 1
chr6_+_163835668 6.187 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr17_-_79828691 6.149 NM_001185077
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr2_+_85198176 6.126 NM_020122
KCMF1
potassium channel modulatory factor 1
chr10_+_114709963 6.117 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr9_-_36258383 6.063 NM_001190383
NM_001190384
NM_005476
GNE


glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase


chr16_-_87525317 6.061 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr12_-_49177876 5.981 NM_015270
ADCY6
adenylate cyclase 6
chr8_-_130951996 5.902 NM_016623
FAM49B
family with sequence similarity 49, member B
chr1_+_110543548 5.901 NM_001242674
AHCYL1
adenosylhomocysteinase-like 1
chr1_-_153940187 5.878 NM_014437
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr12_-_80329234 5.866 NM_001143885
NM_001244990
PPP1R12A

protein phosphatase 1, regulatory subunit 12A

chr1_+_110091185 5.864 NM_006496
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr21_+_18885104 5.847 NM_001207063
NM_001207064
NM_001207065
NM_001207066
NM_001338
CXADR




coxsackie virus and adenovirus receptor




chr11_+_111895537 5.814 NM_001931
DLAT
dihydrolipoamide S-acetyltransferase
chr11_-_8680382 5.789 NM_014818
TRIM66
tripartite motif containing 66
chrX_+_49832214 5.719 NM_000084
CLCN5
chloride channel 5
chr20_+_9198036 5.700 NM_182797
PLCB4
phospholipase C, beta 4
chr11_-_47574766 5.693 NM_006560
CELF1
CUGBP, Elav-like family member 1
chr17_+_75283972 5.681 NM_001113492
SEPT9
septin 9
chr9_+_115983807 5.661 NM_001859
SLC31A1
solute carrier family 31 (copper transporters), member 1
chr1_+_201798281 5.659 NM_018085
IPO9
importin 9
chr10_+_62538088 5.629 NM_001170406
NM_001170407
NM_001786
NM_033379
CDK1



cyclin-dependent kinase 1



chr17_+_34136437 5.610 NM_003487
NM_139215
TAF15

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa

chr12_-_49182718 5.595 NM_020983
ADCY6
adenylate cyclase 6
chr7_-_1595746 5.573 NM_001097620
TMEM184A
transmembrane protein 184A
chr10_+_51565107 5.564 NM_001145260
NM_001145261
NM_001145263
NCOA4


nuclear receptor coactivator 4


chr3_-_57583153 5.541 NM_001660
ARF4
ADP-ribosylation factor 4
chr6_-_109703703 5.451 NM_001142401
NM_001142402
NM_001142403
NM_001142404
NM_006016
CD164




CD164 molecule, sialomucin




chr2_-_47143250 5.396 NM_001171507
NM_001171510
MCFD2

multiple coagulation factor deficiency 2

chrX_-_20284708 5.339 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_+_40723730 5.331 NM_005857
ZMPSTE24
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr3_+_69985750 5.290 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr11_-_115375065 5.275 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr8_-_57906423 5.259 NM_017813
IMPAD1
inositol monophosphatase domain containing 1
chr7_+_129710336 5.257 NM_014997
KLHDC10
kelch domain containing 10
chr10_-_14372807 5.248 NM_018027
FRMD4A
FERM domain containing 4A
chr2_+_169312793 5.231 NM_203463
CERS6
ceramide synthase 6
chr6_-_86352635 5.219 NM_001159673
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr3_+_37903643 5.216 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr14_+_105331581 5.186 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr2_-_47142950 5.086 NM_001171506
NM_001171509
NM_139279
MCFD2


multiple coagulation factor deficiency 2


chr15_+_44829265 5.037 NM_003758
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr17_+_37617688 5.030 NM_015083
NM_016507
CDK12

cyclin-dependent kinase 12

chr19_+_34663311 5.010 NM_001114093
NM_015578
LSM14A

LSM14A, SCD6 homolog A (S. cerevisiae)

chr1_+_212208918 5.004 NM_016448
DTL
denticleless homolog (Drosophila)
chr6_-_86352564 4.987 NM_001159674
NM_001253771
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr7_+_94285620 4.986 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr8_+_67687415 4.963 NM_013257
NM_170709
SGK3

serum/glucocorticoid regulated kinase family, member 3

chr10_+_51572363 4.958 NM_005437
NCOA4
nuclear receptor coactivator 4
chr1_-_150947456 4.954 NM_022075
NM_181746
CERS2

ceramide synthase 2

chr22_+_45560529 4.919 NM_153645
NUP50
nucleoporin 50kDa
chr20_-_48770302 4.891 NM_001162505
NM_199129
NM_199203
TMEM189

TMEM189-UBE2V1
transmembrane protein 189

TMEM189-UBE2V1 readthrough
chr6_-_86351156 4.882 NM_001159675
NM_001159676
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr10_+_75757847 4.878 NM_003373
NM_014000
VCL

vinculin

chr6_+_88182624 4.808 NM_001168398
NM_006416
SLC35A1

solute carrier family 35 (CMP-sialic acid transporter), member A1

chr14_-_75179739 4.791 NM_001039479
KIAA0317
KIAA0317
chr21_-_15755439 4.771 NM_006948
HSPA13
heat shock protein 70kDa family, member 13
chr17_+_75471324 4.729 NM_001113495
SEPT9
septin 9
chr2_-_216300770 4.656 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr1_-_95392501 4.650 NM_001839
CNN3
calponin 3, acidic
chr9_+_137533643 4.614 NM_000093
COL5A1
collagen, type V, alpha 1
chr3_-_182698291 4.552 NM_020640
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.25 1.68e-11 GO:0009987 cellular process
1.34 1.89e-07 GO:0050789 regulation of biological process
1.36 2.21e-07 GO:0050794 regulation of cellular process
1.87 1.31e-06 GO:0006464 protein modification process
1.30 2.87e-06 GO:0065007 biological regulation
1.56 3.78e-06 GO:0051179 localization
1.81 4.95e-06 GO:0043412 macromolecule modification
1.46 1.51e-05 GO:0044260 cellular macromolecule metabolic process
1.46 7.40e-05 GO:0051716 cellular response to stimulus
1.33 7.51e-05 GO:0044237 cellular metabolic process
1.39 1.02e-04 GO:0043170 macromolecule metabolic process
1.92 1.15e-04 GO:0033036 macromolecule localization
1.58 2.34e-04 GO:0048518 positive regulation of biological process
1.32 2.71e-04 GO:0044238 primary metabolic process
2.00 3.05e-04 GO:0008104 protein localization
1.58 7.09e-04 GO:0044267 cellular protein metabolic process
1.46 1.58e-03 GO:0007165 signal transduction
1.46 1.67e-03 GO:0016043 cellular component organization
1.61 1.79e-03 GO:0048523 negative regulation of cellular process
1.43 2.18e-03 GO:0023052 signaling
2.02 2.87e-03 GO:0008219 cell death
2.01 3.33e-03 GO:0016265 death
1.55 3.45e-03 GO:0048522 positive regulation of cellular process
1.26 3.57e-03 GO:0008152 metabolic process
1.44 3.91e-03 GO:0071840 cellular component organization or biogenesis
3.83 4.13e-03 GO:0006184 GTP catabolic process
2.17 5.68e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.76 5.93e-03 GO:0035556 intracellular signal transduction
2.33 6.55e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
3.60 9.87e-03 GO:0046039 GTP metabolic process
1.53 1.15e-02 GO:0048519 negative regulation of biological process
2.07 1.19e-02 GO:0006915 apoptosis
2.63 1.51e-02 GO:0071495 cellular response to endogenous stimulus
2.03 1.74e-02 GO:0012501 programmed cell death
1.64 2.10e-02 GO:0023051 regulation of signaling
1.44 2.61e-02 GO:0019538 protein metabolic process
2.43 2.85e-02 GO:0007264 small GTPase mediated signal transduction
1.37 3.05e-02 GO:0032502 developmental process
2.19 4.54e-02 GO:0034613 cellular protein localization
1.43 4.72e-02 GO:0006810 transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.41 1.46e-16 GO:0005737 cytoplasm
1.25 7.35e-14 GO:0044424 intracellular part
1.23 1.48e-12 GO:0005622 intracellular
1.95 4.26e-09 GO:0031981 nuclear lumen
1.84 9.55e-09 GO:0044428 nuclear part
1.25 1.42e-08 GO:0043229 intracellular organelle
1.25 1.90e-08 GO:0043226 organelle
1.40 2.66e-07 GO:0044446 intracellular organelle part
1.40 3.77e-07 GO:0044422 organelle part
1.37 6.37e-07 GO:0044444 cytoplasmic part
1.26 1.18e-06 GO:0043231 intracellular membrane-bounded organelle
1.25 1.37e-06 GO:0043227 membrane-bounded organelle
1.70 1.46e-06 GO:0043233 organelle lumen
1.69 3.47e-06 GO:0070013 intracellular organelle lumen
1.95 3.73e-06 GO:0005654 nucleoplasm
1.68 3.73e-06 GO:0031974 membrane-enclosed lumen
2.30 1.35e-05 GO:0044451 nucleoplasm part
1.79 2.84e-05 GO:0012505 endomembrane system
1.09 9.34e-05 GO:0044464 cell part
1.09 9.52e-05 GO:0005623 cell
1.51 4.27e-04 GO:0043228 non-membrane-bounded organelle
1.51 4.27e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.67 1.96e-03 GO:0005856 cytoskeleton
1.28 3.79e-03 GO:0005634 nucleus
3.48 4.54e-03 GO:0005769 early endosome
6.38 8.30e-03 GO:0000118 histone deacetylase complex
1.75 2.06e-02 GO:0005794 Golgi apparatus
1.47 3.40e-02 GO:0005829 cytosol
1.37 4.52e-02 GO:0043234 protein complex
2.10 4.69e-02 GO:0005768 endosome
2.58 4.90e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.48 1.16e-17 GO:0005515 protein binding
1.18 1.53e-07 GO:0005488 binding
2.60 5.28e-06 GO:0008092 cytoskeletal protein binding
2.87 1.67e-04 GO:0003779 actin binding
1.93 1.08e-02 GO:0019899 enzyme binding
13.82 4.91e-02 GO:0005338 nucleotide-sugar transmembrane transporter activity
13.82 4.91e-02 GO:0008139 nuclear localization sequence binding