Motif ID: UUGGCAA

Z-value: 0.946


Mature miRNA associated with seed UUGGCAA:

NamemiRBase Accession
hsa-miR-182 MIMAT0000259



Activity profile for motif UUGGCAA.

activity profile for motif UUGGCAA


Sorted Z-values histogram for motif UUGGCAA

Sorted Z-values for motif UUGGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGCAA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_91537724 22.300 NM_003981
NM_199413
NM_199414
 PRC1


protein regulator of cytokinesis 1


chr2_+_235860616 22.070 NM_014521
 SH3BP4
SH3-domain binding protein 4
chr3_-_195808958 18.540 NM_003234
 TFRC
transferrin receptor (p90, CD71)
chr3_-_195808997 18.358 NM_001128148
 TFRC
transferrin receptor (p90, CD71)
chr1_+_165796652 17.844 NM_012474
 UCK2
uridine-cytidine kinase 2
chr2_+_109204904 16.878 NM_001193488
 LIMS1
LIM and senescent cell antigen-like domains 1
chr3_+_180630054 16.777 NM_001013438
NM_001013439
NM_005087
 FXR1


fragile X mental retardation, autosomal homolog 1


chrX_+_119737743 15.409 NM_014060
 MCTS1
malignant T cell amplified sequence 1
chr1_-_94703252 15.345 NM_004815
 ARHGAP29
Rho GTPase activating protein 29
chrX_+_119738542 15.344 NM_001137554
 MCTS1
malignant T cell amplified sequence 1
chr2_+_109204745 15.089 NM_004987
 LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_109237679 14.955 NM_001193484
 LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_48894755 14.597 NM_006801
 KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr14_+_56046796 14.245 NM_001079521
NM_001079522
NM_004986
NM_182926
 KTN1



kinectin 1 (kinesin receptor)



chr11_+_844062 14.158 NM_001025234
 TSPAN4
tetraspanin 4
chr2_+_109223600 13.879 NM_001193482
 LIMS1
LIM and senescent cell antigen-like domains 1
chr18_-_812268 13.691 NM_005433
 YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr5_+_72112417 13.637 NM_002270
 TNPO1
transportin 1
chr12_+_123237302 13.624 NM_003677
 DENR
density-regulated protein
chr11_+_844445 13.509 NM_001025237
 TSPAN4
tetraspanin 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 40 entries
enrichment   p-value GO term description
3.83 4.13e-03 GO:0006184 GTP catabolic process
3.60 9.87e-03 GO:0046039 GTP metabolic process
2.63 1.51e-02 GO:0071495 cellular response to endogenous stimulus
2.43 2.85e-02 GO:0007264 small GTPase mediated signal transduction
2.33 6.55e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.19 4.54e-02 GO:0034613 cellular protein localization
2.17 5.68e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.07 1.19e-02 GO:0006915 apoptosis
2.03 1.74e-02 GO:0012501 programmed cell death
2.02 2.87e-03 GO:0008219 cell death
2.01 3.33e-03 GO:0016265 death
2.00 3.05e-04 GO:0008104 protein localization
1.92 1.15e-04 GO:0033036 macromolecule localization
1.87 1.31e-06 GO:0006464 protein modification process
1.81 4.95e-06 GO:0043412 macromolecule modification
1.76 5.93e-03 GO:0035556 intracellular signal transduction
1.64 2.10e-02 GO:0023051 regulation of signaling
1.61 1.79e-03 GO:0048523 negative regulation of cellular process
1.58 2.34e-04 GO:0048518 positive regulation of biological process
1.58 7.09e-04 GO:0044267 cellular protein metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
6.38 8.30e-03 GO:0000118 histone deacetylase complex
3.48 4.54e-03 GO:0005769 early endosome
2.58 4.90e-02 GO:0016323 basolateral plasma membrane
2.30 1.35e-05 GO:0044451 nucleoplasm part
2.10 4.69e-02 GO:0005768 endosome
1.95 4.26e-09 GO:0031981 nuclear lumen
1.95 3.73e-06 GO:0005654 nucleoplasm
1.84 9.55e-09 GO:0044428 nuclear part
1.79 2.84e-05 GO:0012505 endomembrane system
1.75 2.06e-02 GO:0005794 Golgi apparatus
1.70 1.46e-06 GO:0043233 organelle lumen
1.69 3.47e-06 GO:0070013 intracellular organelle lumen
1.68 3.73e-06 GO:0031974 membrane-enclosed lumen
1.67 1.96e-03 GO:0005856 cytoskeleton
1.51 4.27e-04 GO:0043228 non-membrane-bounded organelle
1.51 4.27e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.47 3.40e-02 GO:0005829 cytosol
1.41 1.46e-16 GO:0005737 cytoplasm
1.40 2.66e-07 GO:0044446 intracellular organelle part
1.40 3.77e-07 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
13.82 4.91e-02 GO:0005338 nucleotide-sugar transmembrane transporter activity
13.82 4.91e-02 GO:0008139 nuclear localization sequence binding
2.87 1.67e-04 GO:0003779 actin binding
2.60 5.28e-06 GO:0008092 cytoskeletal protein binding
1.93 1.08e-02 GO:0019899 enzyme binding
1.48 1.16e-17 GO:0005515 protein binding
1.18 1.53e-07 GO:0005488 binding