Motif ID: UUGUUCG

Z-value: 1.082


Mature miRNA associated with seed UUGUUCG:

NamemiRBase Accession
hsa-miR-375 MIMAT0000728



Activity profile for motif UUGUUCG.

activity profile for motif UUGUUCG


Sorted Z-values histogram for motif UUGUUCG

Sorted Z-values for motif UUGUUCG



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGUUCG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_38599651 9.330 NM_001552
 IGFBP4
insulin-like growth factor binding protein 4
chr10_-_28571014 9.298 NM_173496
 MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr5_+_134240752 9.293 NM_032151
 PCBD2
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr2_+_242641310 8.767 NM_032329
 ING5
inhibitor of growth family, member 5
chr4_+_95679075 8.204 NM_001203
 BMPR1B
bone morphogenetic protein receptor, type IB
chr5_-_58334936 7.529 NM_001197221
NM_001197222
 PDE4D

phosphodiesterase 4D, cAMP-specific

chr3_-_114343052 7.394 NM_001164347
 ZBTB20
zinc finger and BTB domain containing 20
chr3_-_114343791 7.238 NM_001164346
 ZBTB20
zinc finger and BTB domain containing 20
chr14_-_81687265 7.194 NM_015859
 GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr9_+_127539382 6.950 NM_182487
 OLFML2A
olfactomedin-like 2A
chr6_+_71123105 6.881 NM_001105531
NM_020819
 FAM135A

family with sequence similarity 135, member A

chr14_-_81687574 6.878 NM_201595
 GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr9_-_23821842 6.746 NM_001171195
 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr13_+_73633097 6.694 NM_001730
 KLF5
Kruppel-like factor 5 (intestinal)
chr7_-_130080823 6.391 NM_018718
 CEP41
centrosomal protein 41kDa
chr5_+_40909558 6.345 NM_000587
 C7
complement component 7
chr2_+_9346876 6.131 NM_001135191
NM_003887
 ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr16_+_2587951 6.094 NM_002613
NM_031268
 PDPK1

3-phosphoinositide dependent protein kinase-1

chr9_-_23826062 6.076 NM_004432
 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_+_130126035 6.046 NM_177524
 MEST
mesoderm specific transcript homolog (mouse)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 73 entries
enrichment   p-value GO term description
35.78 3.90e-02 GO:0021563 glossopharyngeal nerve development
35.78 3.90e-02 GO:0021615 glossopharyngeal nerve morphogenesis
5.00 3.41e-03 GO:0030324 lung development
4.85 4.91e-03 GO:0030323 respiratory tube development
4.84 8.70e-04 GO:0060541 respiratory system development
4.15 7.08e-05 GO:0048732 gland development
4.01 1.97e-02 GO:0048705 skeletal system morphogenesis
3.95 2.81e-03 GO:0009952 anterior/posterior pattern formation
3.84 1.66e-02 GO:0001655 urogenital system development
3.73 2.34e-02 GO:0043062 extracellular structure organization
3.40 3.53e-05 GO:0001501 skeletal system development
3.21 1.07e-03 GO:0001944 vasculature development
3.18 2.12e-03 GO:0035295 tube development
3.16 3.94e-03 GO:0001568 blood vessel development
2.91 3.41e-05 GO:0072358 cardiovascular system development
2.91 3.41e-05 GO:0072359 circulatory system development
2.74 4.02e-02 GO:0007610 behavior
2.45 2.50e-02 GO:0051094 positive regulation of developmental process
2.42 4.36e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
2.38 2.98e-03 GO:0009887 organ morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.49 3.84e-03 GO:0045202 synapse
1.88 1.52e-02 GO:0042995 cell projection
1.70 2.26e-02 GO:0005887 integral to plasma membrane
1.67 3.68e-02 GO:0031226 intrinsic to plasma membrane
1.51 1.68e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
11.18 2.12e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
8.95 1.52e-02 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
8.95 1.52e-02 GO:0042169 SH2 domain binding
8.59 1.96e-02 GO:0004112 cyclic-nucleotide phosphodiesterase activity
2.93 1.16e-02 GO:0019900 kinase binding
2.51 4.45e-02 GO:0016564 transcription repressor activity
2.39 4.78e-05 GO:0043565 sequence-specific DNA binding
2.33 1.75e-07 GO:0030528 transcription regulator activity
1.89 5.94e-03 GO:0001071 nucleic acid binding transcription factor activity
1.89 5.94e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.17 8.25e-06 GO:0005488 binding