Motif ID: UUUUUGC

Z-value: 3.747


Mature miRNA associated with seed UUUUUGC:

NamemiRBase Accession
hsa-miR-129-5p MIMAT0000242



Activity profile for motif UUUUUGC.

activity profile for motif UUUUUGC


Sorted Z-values histogram for motif UUUUUGC

Sorted Z-values for motif UUUUUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUUUUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_74710356 79.233 NM_032779
CCDC142
coiled-coil domain containing 142
chr9_-_4741798 69.129 NM_001199855
AK3
adenylate kinase 3
chr9_-_4741267 67.702 NM_001199852
NM_016282
AK3

adenylate kinase 3

chr9_-_4741085 64.455 NM_001199854
AK3
adenylate kinase 3
chr9_-_4742042 64.224 NM_001199853
AK3
adenylate kinase 3
chr4_+_76439653 62.521 NM_144721
THAP6
THAP domain containing 6
chr9_-_4726226 60.127 NM_001199856
AK3
adenylate kinase 3
chr17_-_1733083 57.217 NM_052928
SMYD4
SET and MYND domain containing 4
chr7_-_16460946 56.336 NM_001101417
NM_001101426
ISPD

isoprenoid synthase domain containing

chr19_-_49576120 53.393 NM_031886
KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
chr16_+_66914380 51.576 NM_020786
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr19_-_58427934 50.033 NM_152475
ZNF417
zinc finger protein 417
chrX_-_40506800 49.483 NM_144970
CXorf38
chromosome X open reading frame 38
chr8_-_27941387 48.728 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr4_-_166034003 45.549 NM_001100389
TMEM192
transmembrane protein 192
chr17_-_74236272 45.491 NM_052916
RNF157
ring finger protein 157
chr1_+_24882565 43.883 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr19_-_9731883 43.319 NM_152289
ZNF561
zinc finger protein 561
chr1_-_160001723 42.836 NM_145167
PIGM
phosphatidylinositol glycan anchor biosynthesis, class M
chr3_-_15468981 41.495 NM_152396
METTL6
methyltransferase like 6
chr14_+_92790151 40.254 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr19_+_21264952 38.903 NM_182515
ZNF714
zinc finger protein 714
chr18_-_21017816 37.698 NM_032933
TMEM241
transmembrane protein 241
chr14_+_92789536 37.444 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr15_-_65425650 36.780 NM_005707
PDCD7
programmed cell death 7
chr6_+_43543877 36.775 NM_006502
POLH
polymerase (DNA directed), eta
chr1_+_10003485 36.245 NM_022787
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr21_-_47743753 35.549 NM_058180
C21orf58
chromosome 21 open reading frame 58
chr19_+_2841432 35.464 NM_001172775
NM_152791
ZNF555

zinc finger protein 555

chr5_-_43412417 35.159 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr19_-_37407079 35.011 NM_001037232
ZNF829
zinc finger protein 829
chr5_+_130506635 34.445 NM_181705
LYRM7
Lyrm7 homolog (mouse)
chr1_-_151882360 34.344 NM_053055
THEM4
thioesterase superfamily member 4
chr19_+_4639526 34.206 NM_152362
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr11_-_102962903 34.035 NM_032299
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr15_+_44580870 32.728 NM_138423
NM_177974
CASC4

cancer susceptibility candidate 4

chr14_+_92788924 31.758 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_-_141944441 31.427 NM_001039547
GK5
glycerol kinase 5 (putative)
chr13_-_30881141 31.247 NM_001014380
KATNAL1
katanin p60 subunit A-like 1
chr3_+_150264514 30.936 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr2_+_113033146 30.696 NM_198581
ZC3H6
zinc finger CCCH-type containing 6
chr19_-_12595625 30.656 NM_152601
ZNF709
zinc finger protein 709
chr19_+_39881950 30.510 NM_017592
MED29
mediator complex subunit 29
chr6_-_44280986 30.449 NM_020745
AARS2
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr16_+_58283819 30.399 NM_001142302
NM_014157
CCDC113

coiled-coil domain containing 113

chr13_-_41706587 30.329 NM_152903
KBTBD6
kelch repeat and BTB (POZ) domain containing 6
chr6_+_150920998 30.322 NM_001029884
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr4_-_88141614 30.264 NM_020803
KLHL8
kelch-like 8 (Drosophila)
chr1_+_33004771 30.228 NM_001040441
ZBTB8A
zinc finger and BTB domain containing 8A
chr13_+_103451398 29.938 NM_001159596
NM_017693
BIVM

basic, immunoglobulin-like variable motif containing

chr13_-_30881556 29.753 NM_032116
KATNAL1
katanin p60 subunit A-like 1
chr8_+_94767071 29.515 NM_001142301
NM_153704
TMEM67

transmembrane protein 67

chr16_-_3627353 29.453 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr11_-_113746205 29.384 NM_020886
USP28
ubiquitin specific peptidase 28
chrX_-_103401607 29.270 NM_001012755
MCART6
mitochondrial carrier triple repeat 6
chr17_-_1613661 29.218 NM_001164407
TLCD2
TLC domain containing 2
chr7_+_138916230 29.148 NM_173569
UBN2
ubinuclein 2
chr15_-_50978983 29.119 NM_017672
TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr14_-_53620032 28.389 NM_001160147
NM_001160148
NM_030637
DDHD1


DDHD domain containing 1


chr15_-_33360084 28.367 NM_001103184
FMN1
formin 1
chr20_+_43595119 27.863 NM_006282
STK4
serine/threonine kinase 4
chr3_+_40566341 27.673 NM_001098414
NM_198484
ZNF621

zinc finger protein 621

chr1_-_11866079 27.668 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr6_+_111580481 27.452 NM_153369
KIAA1919
KIAA1919
chr19_-_39523132 27.407 NM_178820
FBXO27
F-box protein 27
chr1_+_244998592 27.373 NM_198076
FAM36A
family with sequence similarity 36, member A
chr17_+_57232859 27.355 NM_018304
PRR11
proline rich 11
chr16_-_46865039 27.314 NM_001001436
C16orf87
chromosome 16 open reading frame 87
chr9_+_74526369 26.830 NM_182505
C9orf85
chromosome 9 open reading frame 85
chr9_+_98637899 26.665 NM_001010895
C9orf102
chromosome 9 open reading frame 102
chr9_-_86571652 26.586 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr1_-_247267625 26.573 NM_001142572
NM_024804
ZNF669

zinc finger protein 669

chr17_-_26941178 26.201 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr1_-_160492982 25.966 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr19_+_52956758 25.928 NM_001099694
ZNF578
zinc finger protein 578
chr3_+_42947649 25.926 NM_001134656
ZNF662
zinc finger protein 662
chr10_+_38299525 25.702 NM_006954
NM_006974
ZNF33A

zinc finger protein 33A

chr10_-_46970595 25.523 NM_031912
NM_181519
SYT15

synaptotagmin XV

chr19_+_37997840 25.509 NM_001013659
ZNF793
zinc finger protein 793
chr18_-_65183922 25.495 NM_032160
DSEL
dermatan sulfate epimerase-like
chr3_-_132441302 25.450 NM_153240
NPHP3-ACAD11
NPHP3
NPHP3-ACAD11 readthrough
nephronophthisis 3 (adolescent)
chrX_-_67653169 25.190 NM_002547
OPHN1
oligophrenin 1
chr11_+_92085261 25.024 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr5_-_138775213 24.867 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr3_-_15140652 24.635 NM_022340
ZFYVE20
zinc finger, FYVE domain containing 20
chr3_+_42947401 24.495 NM_207404
ZNF662
zinc finger protein 662
chr1_+_38261079 24.463 NM_152496
MANEAL
mannosidase, endo-alpha-like
chr4_+_123844210 24.455 NM_145207
SPATA5
spermatogenesis associated 5
chr6_+_11538486 24.294 NM_001100829
TMEM170B
transmembrane protein 170B
chr19_-_12444435 23.996 NM_145276
ZNF563
zinc finger protein 563
chr12_+_123717843 23.991 NM_152269
NM_001194995
C12orf65

chromosome 12 open reading frame 65

chr19_+_52772823 23.896 NM_001010851
ZNF766
zinc finger protein 766
chr17_-_18218203 23.840 NM_004618
TOP3A
topoisomerase (DNA) III alpha
chr19_+_37407230 23.832 NM_001204835
NM_001204836
NM_001204837
NM_001204838
NM_001204839
NM_198539
ZNF568





zinc finger protein 568





chr3_-_9994057 23.810 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr3_-_194991778 23.747 NM_152531
XXYLT1
xyloside xylosyltransferase 1
chrX_+_64708614 23.712 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr1_+_38259458 23.558 NM_001031740
NM_001113482
MANEAL

mannosidase, endo-alpha-like

chr16_-_4292052 23.454 NM_001098814
SRL
sarcalumenin
chr2_-_175351755 23.174 NM_001033045
NM_152529
GPR155

G protein-coupled receptor 155

chr13_+_50202434 23.053 NM_138450
ARL11
ADP-ribosylation factor-like 11
chr11_+_117070039 22.868 NM_001001522
NM_003186
TAGLN

transgelin

chr14_-_45431121 22.842 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr12_-_42538432 22.831 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr16_+_71660063 22.705 NM_001017967
NM_052858
MARVELD3

MARVEL domain containing 3

chr2_-_68384575 22.667 NM_138458
WDR92
WD repeat domain 92
chr15_+_59063389 22.642 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr2_-_62081049 22.537 NM_001201543
NM_032180
FAM161A

family with sequence similarity 161, member A

chrX_-_14047958 22.287 NM_001042479
NM_001042480
NM_017856
GEMIN8


gem (nuclear organelle) associated protein 8


chr11_-_777470 22.230 NM_182612
PDDC1
Parkinson disease 7 domain containing 1
chr18_-_14132426 22.154 NM_145287
ZNF519
zinc finger protein 519
chr7_-_102105307 22.144 NM_017621
ALKBH4
alkB, alkylation repair homolog 4 (E. coli)
chr19_-_53238290 21.969 NM_001161501
NM_001161499
NM_001161500
ZNF611


zinc finger protein 611


chrX_+_69282340 21.946 NM_207320
OTUD6A
OTU domain containing 6A
chr3_-_120068077 21.741 NM_001099678
LRRC58
leucine rich repeat containing 58
chr11_+_28129797 21.727 NM_001113528
NM_152636
METTL15

methyltransferase like 15

chr18_-_57364643 21.708 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr16_+_29674282 21.552 NM_001030288
SPN
sialophorin
chr3_-_49466744 21.407 NM_032316
NICN1
nicolin 1
chr6_+_117002349 21.352 NM_002269
KPNA5
karyopherin alpha 5 (importin alpha 6)
chr6_-_46293628 21.325 NM_005822
RCAN2
regulator of calcineurin 2
chr1_-_173793776 21.139 NM_001127181
NM_033319
CENPL

centromere protein L

chr1_-_173793268 20.971 NM_001171182
CENPL
centromere protein L
chr7_+_20655244 20.804 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr19_-_36870064 20.791 NM_020917
ZFP14
zinc finger protein 14 homolog (mouse)
chr5_+_125936606 20.776 NM_032177
PHAX
phosphorylated adaptor for RNA export
chr15_+_42867708 20.739 NM_020759
STARD9
StAR-related lipid transfer (START) domain containing 9
chr9_-_215892 20.426 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr1_-_114430168 20.279 NM_001010922
BCL2L15
BCL2-like 15
chr17_-_72889704 20.029 NM_178128
FADS6
fatty acid desaturase domain family, member 6
chr17_+_28268622 20.021 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr1_+_160085519 19.962 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr2_-_208489972 19.901 NM_001127395
METTL21A
methyltransferase like 21A
chr8_-_9009050 19.858 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr17_+_36507708 19.778 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr3_-_128879873 19.775 NM_001204890
NM_001199469
NM_020701
ISY1-RAB43
ISY1

ISY1-RAB43 readthrough
ISY1 splicing factor homolog (S. cerevisiae)

chr8_-_38386174 19.711 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr5_+_172483285 19.690 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr19_+_48774653 19.652 NM_153608
ZNF114
zinc finger protein 114
chr12_-_66563782 19.622 NM_016056
TMBIM4
transmembrane BAX inhibitor motif containing 4
chr4_+_48018775 19.607 NM_207330
NIPAL1
NIPA-like domain containing 1
chr12_-_66524501 19.588 NM_032338
LLPH
LLP homolog, long-term synaptic facilitation (Aplysia)
chr11_-_74109417 19.490 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr2_-_208489695 19.490 NM_145280
METTL21A
methyltransferase like 21A
chr16_+_29674568 19.454 NM_003123
SPN
sialophorin
chr10_-_79789290 19.447 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr2_-_62733475 19.445 NM_198276
TMEM17
transmembrane protein 17
chr2_-_152830448 19.428 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr7_+_89975977 19.372 NM_001042717
NM_033107
GTPBP10

GTP-binding protein 10 (putative)

chr9_-_130829598 19.288 NM_197956
NAIF1
nuclear apoptosis inducing factor 1
chr4_+_40058507 19.229 NM_018177
N4BP2
NEDD4 binding protein 2
chr22_-_32598497 19.171 NM_001159546
RFPL2
ret finger protein-like 2
chr6_+_36853639 19.110 NM_152734
C6orf89
chromosome 6 open reading frame 89
chr3_+_196439211 19.109 NM_001166304
NM_017861
PIGX

phosphatidylinositol glycan anchor biosynthesis, class X

chr7_-_44924946 19.049 NM_033224
PURB
purine-rich element binding protein B
chr6_+_42018250 19.003 NM_138572
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr15_+_42840991 18.961 NM_001130447
NM_018097
HAUS2

HAUS augmin-like complex, subunit 2

chr1_-_85725315 18.826 NM_198077
C1orf52
chromosome 1 open reading frame 52
chr9_+_100395704 18.721 NM_002486
NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr19_-_4302381 18.638 NM_001169126
NM_144615
TMIGD2

transmembrane and immunoglobulin domain containing 2

chr19_+_54466289 18.637 NM_031895
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr4_-_73935408 18.557 NM_173827
COX18
COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr11_-_118661898 18.497 NM_004397
DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chrX_-_54384436 18.452 NM_001002838
NM_020922
WNK3

WNK lysine deficient protein kinase 3

chr4_-_74486100 18.410 NM_177532
NM_201431
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr22_+_29834571 18.248 NM_021026
RFPL1
ret finger protein-like 1
chr14_+_23299083 18.172 NM_178336
NM_180982
NM_181304
NM_181305
NM_181306
NM_181307
MRPL52





mitochondrial ribosomal protein L52





chr17_+_54911452 18.135 NM_003647
DGKE
diacylglycerol kinase, epsilon 64kDa
chr7_-_129845216 17.994 NM_032842
TMEM209
transmembrane protein 209
chr4_-_89205887 17.959 NM_152542
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr6_+_107811272 17.954 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr11_+_12399024 17.898 NM_018222
PARVA
parvin, alpha
chr5_+_137801178 17.871 NM_001964
EGR1
early growth response 1
chr2_-_85839178 17.851 NM_001013649
C2orf68
chromosome 2 open reading frame 68
chr15_+_45879416 17.810 NM_012388
PLDN
pallidin homolog (mouse)
chr7_-_35734762 17.711 NM_022373
HERPUD2
HERPUD family member 2
chr8_+_117950437 17.641 NM_001025357
C8orf85
chromosome 8 open reading frame 85
chrX_+_41583407 17.476 NM_080817
GPR82
G protein-coupled receptor 82
chr6_-_41863086 17.435 NM_018561
USP49
ubiquitin specific peptidase 49
chr3_+_121286777 17.420 NM_001012659
ARGFX
arginine-fifty homeobox
chr10_+_104629209 17.417 NM_020682
AS3MT
arsenic (+3 oxidation state) methyltransferase
chr1_+_44584521 17.142 NM_173484
KLF17
Kruppel-like factor 17
chr19_-_4723814 17.132 NM_139159
DPP9
dipeptidyl-peptidase 9
chr3_-_49314281 17.051 NM_198562
C3orf62
chromosome 3 open reading frame 62
chr9_+_37753769 17.005 NM_144964
RG9MTD3
RNA (guanine-9-) methyltransferase domain containing 3
chr2_-_152955208 17.003 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr15_+_64443909 16.943 NM_024798
SNX22
sorting nexin 22
chr12_+_32654976 16.870 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_89829435 16.852 NM_198460
GBP6
guanylate binding protein family, member 6
chr7_+_12629147 16.637 NM_033128
SCIN
scinderin
chr4_+_7045142 16.636 NM_152293
TADA2B
transcriptional adaptor 2B
chr15_-_64338519 16.577 NM_014326
DAPK2
death-associated protein kinase 2
chr1_+_53192021 16.492 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr17_-_37764165 16.465 NM_006160
NEUROD2
neurogenic differentiation 2
chr12_+_123718290 16.456 NM_001143905
C12orf65
chromosome 12 open reading frame 65
chr17_-_18585571 16.445 NM_001145045
ZNF286B
zinc finger protein 286B
chr2_-_200820458 16.419 NM_001039693
TYW5
tRNA-yW synthesizing protein 5
chr2_-_152118258 16.282 NM_198557
RBM43
RNA binding motif protein 43
chr7_-_148823388 16.213 NM_001001661
ZNF425
zinc finger protein 425
chr22_-_32589386 16.188 NM_006605
RFPL2
ret finger protein-like 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 7.01e-03 GO:0006355 regulation of transcription, DNA-dependent
1.67 1.09e-02 GO:0006468 protein phosphorylation
1.54 2.32e-02 GO:0006793 phosphorus metabolic process
1.54 2.32e-02 GO:0006796 phosphate metabolic process
1.33 3.76e-02 GO:0051252 regulation of RNA metabolic process
1.78 3.98e-02 GO:0019226 transmission of nerve impulse
1.78 3.98e-02 GO:0035637 multicellular organismal signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
4.00 1.93e-03 GO:0043197 dendritic spine
3.84 3.26e-03 GO:0044309 neuron spine
1.80 1.19e-02 GO:0045202 synapse
1.30 1.96e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.51 9.49e-09 GO:0046914 transition metal ion binding
1.34 1.11e-07 GO:0046872 metal ion binding
1.52 1.30e-07 GO:0008270 zinc ion binding
1.33 3.01e-07 GO:0043169 cation binding
1.33 4.09e-07 GO:0043167 ion binding
1.29 3.89e-02 GO:0003677 DNA binding
1.61 4.98e-02 GO:0004672 protein kinase activity