Motif ID: XBP1.p3

Z-value: 3.726


Transcription factors associated with XBP1.p3:

Gene SymbolEntrez IDGene Name
XBP1 7494 X-box binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
XBP1chr22_-_291965370.497.2e-15Click!


Activity profile for motif XBP1.p3.

activity profile for motif XBP1.p3


Sorted Z-values histogram for motif XBP1.p3

Sorted Z-values for motif XBP1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of XBP1.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_171758289 148.665 NM_001135095
 FNDC3B
fibronectin type III domain containing 3B
chr3_-_57583080 129.257 ARF4
ADP-ribosylation factor 4
chr7_-_6523689 108.154 NM_001100603
NM_006854
 KDELR2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

chr3_-_57582866 103.965 ARF4
ADP-ribosylation factor 4
chr3_-_57583090 101.055 ARF4
ADP-ribosylation factor 4
chr2_-_69614321 99.375 NM_001244710
NM_002056
 GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr6_-_7910716 96.791 NM_030810
 TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr1_-_43736600 95.112 EBNA1BP2
EBNA1 binding protein 2
chr6_-_7910278 94.470 NM_001145549
 TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr3_-_57583153 90.534 NM_001660
 ARF4
ADP-ribosylation factor 4
chr7_+_128379345 88.452 NM_001130674
NM_001199671
NM_001199672
NM_001199673
NM_001199674
NM_001219
 CALU





calumenin





chr15_+_79603427 87.183 NM_007364
 TMED3
transmembrane emp24 protein transport domain containing 3
chr15_+_79603497 86.420 TMED3
transmembrane emp24 protein transport domain containing 3
chr3_+_133524671 80.540 SRPRB
signal recognition particle receptor, B subunit
chr15_-_60690115 79.251 NM_001002857
NM_001002858
NM_001136015
NM_004039
 ANXA2



annexin A2



chr3_+_133524636 76.326 SRPRB
signal recognition particle receptor, B subunit
chr12_-_106641675 74.922 NM_006825
 CKAP4
cytoskeleton-associated protein 4
chr3_+_127771287 73.237 SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr7_+_128379400 69.663 CALU
calumenin
chr7_-_54826864 68.085 SEC61G
Sec61 gamma subunit

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 72 entries
enrichment   p-value GO term description
29.79 3.01e-04 GO:0048194 Golgi vesicle budding
29.79 3.01e-04 GO:0048200 Golgi transport vesicle coating
29.79 3.01e-04 GO:0048205 COPI coating of Golgi vesicle
29.79 3.01e-04 GO:0048207 vesicle targeting, rough ER to cis-Golgi
29.79 3.01e-04 GO:0048208 COPII vesicle coating
29.79 3.01e-04 GO:0090114 COPII-coated vesicle budding
26.81 8.05e-10 GO:0048199 vesicle targeting, to, from or within Golgi
26.81 9.08e-03 GO:0045047 protein targeting to ER
26.81 9.08e-03 GO:0072599 establishment of protein localization in endoplasmic reticulum
24.37 1.07e-03 GO:0006613 cotranslational protein targeting to membrane
22.34 8.00e-09 GO:0006901 vesicle coating
22.08 1.41e-05 GO:0070972 protein localization in endoplasmic reticulum
21.45 1.31e-08 GO:0006900 membrane budding
17.87 1.11e-07 GO:0006903 vesicle targeting
15.32 2.00e-03 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
14.11 2.38e-02 GO:0030968 endoplasmic reticulum unfolded protein response
14.11 2.38e-02 GO:0034620 cellular response to unfolded protein
12.77 4.46e-06 GO:0051650 establishment of vesicle localization
11.22 2.60e-11 GO:0018196 peptidyl-asparagine modification
11.22 2.60e-11 GO:0018279 protein N-linked glycosylation via asparagine

Gene overrepresentation in compartment category:

Showing 1 to 20 of 55 entries
enrichment   p-value GO term description
32.17 1.47e-02 GO:0005797 Golgi medial cisterna
26.81 1.84e-03 GO:0030127 COPII vesicle coat
22.98 2.50e-05 GO:0030663 COPI coated vesicle membrane
18.92 9.81e-05 GO:0030137 COPI-coated vesicle
17.87 1.32e-03 GO:0030867 rough endoplasmic reticulum membrane
17.87 1.23e-02 GO:0030126 COPI vesicle coat
16.76 1.89e-03 GO:0012507 ER to Golgi transport vesicle membrane
14.11 4.81e-03 GO:0030134 ER to Golgi transport vesicle
11.00 1.17e-04 GO:0030120 vesicle coat
10.12 9.97e-06 GO:0005793 ER-Golgi intermediate compartment
10.05 5.67e-03 GO:0030660 Golgi-associated vesicle membrane
8.67 9.69e-09 GO:0005788 endoplasmic reticulum lumen
8.47 1.57e-02 GO:0005791 rough endoplasmic reticulum
8.13 8.70e-05 GO:0030117 membrane coat
8.13 8.70e-05 GO:0048475 coated membrane
7.80 1.79e-03 GO:0030176 integral to endoplasmic reticulum membrane
6.95 1.44e-02 GO:0005798 Golgi-associated vesicle
5.96 1.34e-02 GO:0031227 intrinsic to endoplasmic reticulum membrane
5.42 9.84e-03 GO:0042470 melanosome
5.42 9.84e-03 GO:0048770 pigment granule

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
23.83 3.85e-03 GO:0003756 protein disulfide isomerase activity
23.83 3.85e-03 GO:0016862 intramolecular oxidoreductase activity, interconverting keto- and enol-groups
23.83 3.85e-03 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds
13.41 1.72e-04 GO:0015035 protein disulfide oxidoreductase activity
12.11 3.64e-04 GO:0015036 disulfide oxidoreductase activity
8.41 1.18e-03 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors
6.31 1.11e-03 GO:0008565 protein transporter activity
5.87 3.31e-05 GO:0016853 isomerase activity
2.41 2.41e-03 GO:0016491 oxidoreductase activity
1.36 5.10e-05 GO:0005515 protein binding
1.35 1.24e-02 GO:0003824 catalytic activity