Motif ID: YY1.p2

Z-value: 7.383


Transcription factors associated with YY1.p2:

Gene SymbolEntrez IDGene Name
YY1 7528 YY1 transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
YY1chr14_+_1007054320.865.5e-65Click!


Activity profile for motif YY1.p2.

activity profile for motif YY1.p2


Sorted Z-values histogram for motif YY1.p2

Sorted Z-values for motif YY1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of YY1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_97274106 119.585 PTDSS1
phosphatidylserine synthase 1
chr20_-_34243118 115.254 RBM12
RNA binding motif protein 12
chr11_+_114310107 108.628 NM_015523
 REXO2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chrX_-_153285334 105.780 NM_001025242
NM_001025243
NM_001569
 IRAK1


interleukin-1 receptor-associated kinase 1


chr16_-_87903028 104.699 NM_003486
 SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr13_-_37679800 101.687 NM_145203
 CSNK1A1L
casein kinase 1, alpha 1-like
chr17_-_4851688 99.717 PFN1
profilin 1
chr1_-_149900143 96.569 NM_005850
 SF3B4
splicing factor 3b, subunit 4, 49kDa
chr8_+_26149004 93.504 NM_002717
 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr14_-_23504353 92.505 NM_001144932
NM_002797
NM_001130725
 PSMB5


proteasome (prosome, macropain) subunit, beta type, 5


chrX_-_153285262 90.970 IRAK1
interleukin-1 receptor-associated kinase 1
chr2_+_178257371 90.377 NM_003659
 AGPS
alkylglycerone phosphate synthase
chr12_+_96252770 89.233 SNRPF
small nuclear ribonucleoprotein polypeptide F
chr17_-_4851797 88.991 NM_005022
 PFN1
profilin 1
chr20_-_34330093 88.459 RBM39
RNA binding motif protein 39
chr17_-_4851827 84.799 PFN1
profilin 1
chr11_+_69455837 83.789 NM_053056
 CCND1
cyclin D1
chr6_+_36562135 82.457 SRSF3
serine/arginine-rich splicing factor 3
chr2_+_114647699 80.665 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr1_+_203830723 79.412 SNRPE
small nuclear ribonucleoprotein polypeptide E

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 285 entries
enrichment   p-value GO term description
3.88 3.79e-02 GO:0042273 ribosomal large subunit biogenesis
3.63 3.11e-25 GO:0006415 translational termination
3.59 1.53e-23 GO:0019080 viral genome expression
3.59 1.53e-23 GO:0019083 viral transcription
3.50 3.03e-09 GO:0006413 translational initiation
3.38 1.79e-23 GO:0006414 translational elongation
3.34 7.09e-22 GO:0043241 protein complex disassembly
3.34 7.09e-22 GO:0043624 cellular protein complex disassembly
3.24 3.90e-06 GO:0006120 mitochondrial electron transport, NADH to ubiquinone
3.22 1.75e-22 GO:0032984 macromolecular complex disassembly
3.22 1.75e-22 GO:0034623 cellular macromolecular complex disassembly
3.07 1.22e-06 GO:0042773 ATP synthesis coupled electron transport
3.07 1.22e-06 GO:0042775 mitochondrial ATP synthesis coupled electron transport
3.06 3.62e-11 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.00 8.90e-23 GO:0019058 viral infectious cycle
3.00 5.87e-11 GO:0051352 negative regulation of ligase activity
3.00 5.87e-11 GO:0051444 negative regulation of ubiquitin-protein ligase activity
2.98 2.34e-02 GO:0006900 membrane budding
2.94 3.44e-25 GO:0022415 viral reproductive process
2.90 6.93e-07 GO:0006521 regulation of cellular amino acid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 99 entries
enrichment   p-value GO term description
4.30 6.83e-05 GO:0005852 eukaryotic translation initiation factor 3 complex
4.14 1.35e-06 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
3.65 1.65e-10 GO:0022625 cytosolic large ribosomal subunit
3.34 2.33e-17 GO:0022626 cytosolic ribosome
3.29 8.06e-07 GO:0022627 cytosolic small ribosomal subunit
3.26 3.07e-03 GO:0005839 proteasome core complex
3.23 1.47e-07 GO:0005747 mitochondrial respiratory chain complex I
3.23 1.47e-07 GO:0030964 NADH dehydrogenase complex
3.23 1.47e-07 GO:0045271 respiratory chain complex I
3.13 2.48e-15 GO:0071013 catalytic step 2 spliceosome
3.06 1.04e-10 GO:0005746 mitochondrial respiratory chain
2.99 1.75e-08 GO:0015935 small ribosomal subunit
2.97 1.20e-10 GO:0070469 respiratory chain
2.96 5.05e-10 GO:0000502 proteasome complex
2.85 1.59e-20 GO:0005681 spliceosomal complex
2.83 5.35e-03 GO:0001725 stress fiber
2.75 1.46e-07 GO:0015934 large ribosomal subunit
2.68 5.77e-15 GO:0044455 mitochondrial membrane part
2.68 4.68e-03 GO:0042641 actomyosin
2.64 1.91e-02 GO:0032432 actin filament bundle

Gene overrepresentation in function category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
3.28 3.33e-07 GO:0003954 NADH dehydrogenase activity
3.28 3.33e-07 GO:0008137 NADH dehydrogenase (ubiquinone) activity
3.28 3.33e-07 GO:0050136 NADH dehydrogenase (quinone) activity
3.14 1.48e-07 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
3.11 2.58e-08 GO:0003743 translation initiation factor activity
2.97 2.52e-04 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
2.76 3.42e-20 GO:0003735 structural constituent of ribosome
2.76 2.69e-02 GO:0046966 thyroid hormone receptor binding
2.65 5.41e-09 GO:0008135 translation factor activity, nucleic acid binding
2.52 1.72e-02 GO:0043130 ubiquitin binding
2.51 1.14e-02 GO:0032182 small conjugating protein binding
2.42 4.73e-06 GO:0003729 mRNA binding
2.36 1.24e-05 GO:0031625 ubiquitin protein ligase binding
2.33 3.29e-02 GO:0004812 aminoacyl-tRNA ligase activity
2.33 3.29e-02 GO:0016875 ligase activity, forming carbon-oxygen bonds
2.33 3.29e-02 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
2.21 1.50e-02 GO:0003697 single-stranded DNA binding
2.13 8.38e-51 GO:0003723 RNA binding
2.07 3.75e-03 GO:0016651 oxidoreductase activity, acting on NADH or NADPH
2.06 9.35e-07 GO:0003714 transcription corepressor activity