Motif ID: ZBTB6.p2

Z-value: 1.351


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
ZBTB6 10773 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZBTB6chr9_-_125675571-0.152.7e-02Click!


Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_60337350 33.949 NM_021136
 RTN1
reticulon 1
chr11_-_12030882 22.598 NM_013253
 DKK3
dickkopf 3 homolog (Xenopus laevis)
chr10_-_15413054 20.944 NM_001010924
 FAM171A1
family with sequence similarity 171, member A1
chr22_-_39240016 19.494 NM_014293
 NPTXR
neuronal pentraxin receptor
chr11_-_12030838 18.548 DKK3
dickkopf 3 homolog (Xenopus laevis)
chr11_-_12030539 18.297 DKK3
dickkopf 3 homolog (Xenopus laevis)
chr11_-_12030622 17.531 NM_015881
 DKK3
dickkopf 3 homolog (Xenopus laevis)
chr1_+_43996478 13.237 NM_002840
NM_130440
 PTPRF

protein tyrosine phosphatase, receptor type, F

chr9_+_87284625 12.046 NM_001007097
 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr4_+_41258941 11.613 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr17_-_42992852 11.507 NM_001131019
NM_001242376
NM_002055
 GFAP


glial fibrillary acidic protein


chr5_+_17217474 11.408 NM_006317
 BASP1
brain abundant, membrane attached signal protein 1
chr4_+_41258909 11.269 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_+_41258895 11.047 NM_004181
 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr5_+_17217781 10.939 BASP1
brain abundant, membrane attached signal protein 1
chr11_-_12030128 10.828 NM_001018057
 DKK3
dickkopf 3 homolog (Xenopus laevis)
chr9_+_137979513 10.778 OLFM1
olfactomedin 1
chr19_+_36359346 10.581 NM_001024807
NM_005166
 APLP1

amyloid beta (A4) precursor-like protein 1

chr3_-_58563490 10.159 NM_001076778
NM_007177
 FAM107A

family with sequence similarity 107, member A

chr8_+_104512975 10.056 NM_001100117
 RIMS2
regulating synaptic membrane exocytosis 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 99 entries
enrichment   p-value GO term description
2.50 1.03e-03 GO:0010975 regulation of neuron projection development
2.26 4.56e-02 GO:0050890 cognition
2.24 4.02e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.22 4.80e-02 GO:0022604 regulation of cell morphogenesis
2.20 2.71e-03 GO:0010038 response to metal ion
2.20 1.24e-02 GO:0031344 regulation of cell projection organization
2.13 1.61e-03 GO:0045664 regulation of neuron differentiation
2.12 4.91e-11 GO:0019226 transmission of nerve impulse
2.12 4.91e-11 GO:0035637 multicellular organismal signaling
2.12 1.68e-09 GO:0007268 synaptic transmission
2.07 7.03e-05 GO:0010035 response to inorganic substance
2.07 7.03e-05 GO:0051960 regulation of nervous system development
1.99 2.92e-03 GO:0050767 regulation of neurogenesis
1.92 4.60e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.92 8.57e-06 GO:0007409 axonogenesis
1.92 3.44e-04 GO:0007411 axon guidance
1.92 3.39e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.91 5.05e-06 GO:0048812 neuron projection morphogenesis
1.90 5.11e-03 GO:0061061 muscle structure development
1.87 2.12e-06 GO:0048858 cell projection morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 35 entries
enrichment   p-value GO term description
2.89 2.04e-03 GO:0030426 growth cone
2.80 3.52e-03 GO:0030427 site of polarized growth
2.58 4.88e-04 GO:0019717 synaptosome
2.43 3.73e-02 GO:0033267 axon part
2.22 4.18e-02 GO:0005925 focal adhesion
2.15 3.99e-04 GO:0030424 axon
2.07 1.00e-02 GO:0005912 adherens junction
2.03 7.35e-03 GO:0070161 anchoring junction
1.96 8.23e-04 GO:0016323 basolateral plasma membrane
1.89 4.57e-06 GO:0043005 neuron projection
1.79 8.04e-05 GO:0045202 synapse
1.75 1.36e-03 GO:0048471 perinuclear region of cytoplasm
1.69 3.64e-03 GO:0009986 cell surface
1.68 1.95e-05 GO:0030054 cell junction
1.68 3.69e-02 GO:0044456 synapse part
1.54 4.43e-03 GO:0044431 Golgi apparatus part
1.49 5.47e-04 GO:0005626 insoluble fraction
1.49 1.19e-03 GO:0005624 membrane fraction
1.47 3.28e-03 GO:0031982 vesicle
1.47 4.60e-03 GO:0031410 cytoplasmic vesicle

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.87 3.37e-02 GO:0004112 cyclic-nucleotide phosphodiesterase activity
2.09 2.50e-02 GO:0005516 calmodulin binding
1.74 1.11e-05 GO:0008092 cytoskeletal protein binding
1.71 7.38e-04 GO:0019904 protein domain specific binding
1.44 3.63e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.42 3.50e-02 GO:0016301 kinase activity
1.40 1.01e-02 GO:0001071 nucleic acid binding transcription factor activity
1.40 1.01e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.22 1.49e-13 GO:0005515 protein binding
1.11 7.49e-10 GO:0005488 binding