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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: ZIC1..3.p2

Z-value: 2.303

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_6798419	65.491		ZNF384	zinc finger protein 384
chr11_-_111782447	65.049	NM_001885	CRYAB	crystallin, alpha B
chr12_-_45270071	52.149		NELL2	NEL-like 2 (chicken)
chr2_-_26205327	52.145		KIF3C	kinesin family member 3C
chr12_-_45269953	48.473		NELL2	NEL-like 2 (chicken)
chr6_-_29595934	48.184	NM_021903	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr14_-_103988829	45.955		CKB	creatine kinase, brain
chr12_-_45270157	42.183	NM_001145108 NM_006159	NELL2	NEL-like 2 (chicken)
chr11_-_12030539	41.786		DKK3	dickkopf 3 homolog (Xenopus laevis)
chr14_+_29236882	36.194		FOXG1	forkhead box G1
chr12_+_79258588	35.682		SYT1	synaptotagmin I
chr5_+_175792444	35.381	NM_173664	ARL10	ADP-ribosylation factor-like 10
chrX_-_48858617	35.009	NM_020137 NM_207672	GRIPAP1	GRIP1 associated protein 1
chr14_-_103989195	34.950	NM_001823	CKB	creatine kinase, brain
chr14_+_101292483	33.021
chr12_+_79258517	32.851		SYT1	synaptotagmin I
chrX_-_13956445	32.266
chr11_-_12030622	31.941	NM_015881	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr14_-_103989112	31.736		CKB	creatine kinase, brain
chr9_-_113800243	31.145	NM_001401 NM_057159	LPAR1	lysophosphatidic acid receptor 1
chr11_-_12030128	30.384	NM_001018057	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr14_+_101292451	30.349		MEG3	maternally expressed 3 (non-protein coding)
chr1_-_38512446	30.092	NM_002699	POU3F1	POU class 3 homeobox 1
chr13_-_30881141	28.652	NM_001014380	KATNAL1	katanin p60 subunit A-like 1
chr12_-_49392909	27.765	NM_015086	DDN	dendrin
chr12_-_6798528	27.708	NM_133476	ZNF384	zinc finger protein 384
chr13_-_30881556	26.329	NM_032116	KATNAL1	katanin p60 subunit A-like 1
chr11_+_62439134	25.806		C11orf83	chromosome 11 open reading frame 83
chr6_-_29595746	25.805		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr22_-_44258210	25.784	NM_014351	SULT4A1	sulfotransferase family 4A, member 1
chr7_-_150946031	25.638		SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr11_+_62439120	25.373	NM_001085372	C11orf83	chromosome 11 open reading frame 83
chr5_+_71403040	25.142	NM_005909	MAP1B	microtubule-associated protein 1B
chr21_-_34100210	25.003		SYNJ1	synaptojanin 1
chr3_-_73673978	24.347	NM_015009	PDZRN3	PDZ domain containing ring finger 3
chr2_-_26205437	23.792	NM_002254	KIF3C	kinesin family member 3C
chr15_+_84115979	23.601	NM_003027	SH3GL3	SH3-domain GRB2-like 3
chr1_-_156217717	23.458	NM_198406 NM_024897	PAQR6	progestin and adipoQ receptor family member VI
chr6_-_6007632	23.203	NM_016588	NRN1	neuritin 1
chr12_-_6798619	23.177	NM_001039920 NM_001135734	ZNF384	zinc finger protein 384
chr12_+_79258794	22.967		SYT1	synaptotagmin I
chr12_-_45270632	22.857	NM_001145107	NELL2	NEL-like 2 (chicken)
chr15_+_74421698	22.196	NM_001130136	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr15_+_74421986	21.859	NM_001130137	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chrX_-_107979606	21.762	NM_003604	IRS4	insulin receptor substrate 4
chr12_-_45269340	21.600	NM_001145109	NELL2	NEL-like 2 (chicken)
chr2_-_201936386	21.587		FAM126B	family with sequence similarity 126, member B
chr20_+_36149606	21.209	NM_005386 NM_181689	NNAT	neuronatin
chrX_-_51812249	21.181	NM_001098800 NM_001242362 NM_030801 NM_177535 NM_177537	MAGED4 MAGED4B	melanoma antigen family D, 4 melanoma antigen family D, 4B
chr17_+_40834571	20.989	NM_003632	CNTNAP1	contactin associated protein 1
chr6_-_29600959	20.828	NM_001470 NM_021904	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr11_-_123525300	20.764	NM_001040151 NM_018400	SCN3B	sodium channel, voltage-gated, type III, beta
chrX_+_101906293	20.763	NM_001099410 NM_001099411 NM_014710 NM_001184727	GPRASP1	G protein-coupled receptor associated sorting protein 1
chr2_+_149633173	20.538
chr6_-_29600859	20.483		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr6_-_29600668	20.331		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chrX_-_13956530	20.238		GPM6B	glycoprotein M6B
chr11_+_111783476	19.759		HSPB2-C11orf52 HSPB2	HSPB2-C11orf52 readthrough (non-protein coding) heat shock 27kDa protein 2
chr5_+_161275541	19.486	NM_001127645	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr17_-_27278324	19.375		PHF12	PHD finger protein 12
chrX_+_134166318	19.372	NM_001078171	FAM127A	family with sequence similarity 127, member A
chr11_+_111783459	19.348	NM_001541	HSPB2-C11orf52 HSPB2	HSPB2-C11orf52 readthrough (non-protein coding) heat shock 27kDa protein 2
chr12_-_53448167	19.303		LOC283335	uncharacterized LOC283335
chr14_-_21270537	19.055	NM_198232	RNASE1	ribonuclease, RNase A family, 1 (pancreatic)
chr9_+_130965666	18.736		DNM1	dynamin 1
chr14_+_65007418	18.401		HSPA2	heat shock 70kDa protein 2
chr12_-_122018858	18.142	NM_032590	KDM2B	lysine (K)-specific demethylase 2B
chr11_-_123524881	17.310		SCN3B	sodium channel, voltage-gated, type III, beta
chr11_-_117186918	17.154	NM_012104 NM_138971 NM_138972 NM_138973	BACE1	beta-site APP-cleaving enzyme 1
chr3_+_10028579	17.040		LOC442075	uncharacterized LOC442075
chr9_-_122131579	17.017	NM_014618	DBC1	deleted in bladder cancer 1
chr11_+_124609775	17.004	NM_001126181 NM_006176	NRGN	neurogranin (protein kinase C substrate, RC3)
chrX_+_103031797	16.791		PLP1	proteolipid protein 1
chr8_+_21916858	16.681		EPB49	erythrocyte membrane protein band 4.9 (dematin)
chrX_-_13956644	16.649	NM_001001994	GPM6B	glycoprotein M6B
chr7_-_108096693	16.622	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr10_-_95360959	16.576	NM_006744	RBP4	retinol binding protein 4, plasma
chr11_+_124609841	16.569		NRGN	neurogranin (protein kinase C substrate, RC3)
chr7_-_99680358	16.499		ZNF3	zinc finger protein 3
chr9_+_130965608	16.411	NM_001005336 NM_004408	DNM1	dynamin 1
chr11_-_66115016	16.325	NM_006876	B3GNT1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr3_+_10068123	16.162		FANCD2	Fanconi anemia, complementation group D2
chr20_+_44650260	16.015	NM_001134771	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chrX_+_51927918	15.950	NM_001098800 NM_001242362 NM_030801 NM_177535 NM_177537	MAGED4 MAGED4B	melanoma antigen family D, 4 melanoma antigen family D, 4B
chr21_-_34100316	15.949	NM_003895 NM_203446	SYNJ1	synaptojanin 1
chr16_+_6533758	15.867		RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_-_7197896	15.778		YBX2	Y box binding protein 2
chrX_+_70443055	15.571	NM_000166	GJB1	gap junction protein, beta 1, 32kDa
chrX_+_13671224	15.546	NM_152634	TCEANC	transcription elongation factor A (SII) N-terminal and central domain containing
chr9_+_130965668	15.541		DNM1	dynamin 1
chr3_-_10067989	15.508		CIDECP	cell death-inducing DFFA-like effector c pseudogene
chr17_-_5404304	15.503	NM_001162371	LOC728392	uncharacterized LOC728392
chr17_-_7197811	15.499		YBX2	Y box binding protein 2
chr9_-_123476578	15.418	NM_001080497	MEGF9	multiple EGF-like-domains 9
chr3_+_10068097	15.375	NM_001018115 NM_033084	FANCD2	Fanconi anemia, complementation group D2
chr19_-_46295647	15.260		DMWD	dystrophia myotonica, WD repeat containing
chrX_+_70364707	15.241		NLGN3	neuroligin 3
chr8_+_21916685	15.237	NM_001114138 NM_001978	EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr4_-_176733901	15.229		GPM6A	glycoprotein M6A
chr14_+_101193313	15.216		DLK1	delta-like 1 homolog (Drosophila)
chr10_-_90712510	14.985	NM_001613	ACTA2	actin, alpha 2, smooth muscle, aorta
chr21_-_34100228	14.967	NM_001160302 NM_001160306	SYNJ1	synaptojanin 1
chr12_+_13197284	14.710	NM_020853	KIAA1467	KIAA1467
chr3_-_195306274	14.659		APOD	apolipoprotein D
chr14_-_24584125	14.650		NRL	neural retina leucine zipper
chr19_+_58790306	14.549	NM_021089	ZNF8	zinc finger protein 8
chr14_-_51561657	14.480		TRIM9	tripartite motif containing 9
chr14_+_29236171	14.421	NM_005249	FOXG1	forkhead box G1
chr1_-_150602047	14.412		ENSA	endosulfine alpha
chr12_+_48499655	14.396	NM_001166686	PFKM	phosphofructokinase, muscle
chr17_-_7197866	14.303	NM_015982	YBX2	Y box binding protein 2
chr3_-_149688638	14.156	NM_002628 NM_053024	PFN2	profilin 2
chr14_+_65007163	14.110	NM_021979	HSPA2	heat shock 70kDa protein 2
chr16_+_69796237	14.073	NM_007014 NM_199423	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr15_-_83316621	13.973	NM_030594	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr2_+_17935124	13.949	NM_182625	GEN1	Gen endonuclease homolog 1 (Drosophila)
chr2_+_25016174	13.816	NM_001199803 NM_024322	CENPO	centromere protein O
chr19_-_47164289	13.805	NM_145056	DACT3	dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr3_+_184053682	13.790	NM_001171093	FAM131A	family with sequence similarity 131, member A
chrX_+_70364728	13.736		NLGN3	neuroligin 3
chr1_+_99730067	13.700		LPPR4	lipid phosphate phosphatase-related protein type 4
chr15_+_84116172	13.576		SH3GL3	SH3-domain GRB2-like 3
chr15_+_41851153	13.496	NM_006293	TYRO3	TYRO3 protein tyrosine kinase
chr1_-_27930360	13.472		AHDC1	AT hook, DNA binding motif, containing 1
chr2_-_241500459	13.468		ANKMY1	ankyrin repeat and MYND domain containing 1
chr19_+_35521591	13.424	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chr22_-_18484183	13.419		MICAL3	microtubule associated monoxygenase, calponin and LIM domain containing 3
chr5_+_140346053	13.388		PCDHAC2	protocadherin alpha subfamily C, 2
chr3_-_149688886	13.384		PFN2	profilin 2
chr5_-_11904127	13.375		CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr1_-_85930610	13.351		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr7_-_150945731	13.280	NM_001003801	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr17_-_80656461	13.227	NM_006822	RAB40B	RAB40B, member RAS oncogene family
chr1_+_155829259	13.223	NM_152280	SYT11	synaptotagmin XI
chr16_+_55542909	13.223	NM_017839	LPCAT2	lysophosphatidylcholine acyltransferase 2
chr5_+_140346289	13.146	NM_031883	PCDHAC2	protocadherin alpha subfamily C, 2
chr1_-_241520384	13.120		RGS7	regulator of G-protein signaling 7
chr17_-_8066254	13.109	NM_014232	VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr1_-_241520467	13.095	NM_002924	RGS7	regulator of G-protein signaling 7
chr3_+_50306305	13.086		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chrX_+_70364680	13.059	NM_001166660 NM_018977 NM_181303	NLGN3	neuroligin 3
chr2_-_237172987	13.020	NM_212556	ASB18	ankyrin repeat and SOCS box containing 18
chr8_+_19796730	13.012		LPL	lipoprotein lipase
chr12_+_112451229	12.937
chr3_+_49591897	12.852	NM_003458	BSN	bassoon (presynaptic cytomatrix protein)
chr16_-_31483425	12.825
chrX_-_138287180	12.807	NM_001139498 NM_001139500 NM_001139501	FGF13	fibroblast growth factor 13
chr7_+_64498643	12.766		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr17_-_37557851	12.743	NM_001184906 NM_032875	FBXL20	F-box and leucine-rich repeat protein 20
chrX_-_15872871	12.652		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr14_+_101193190	12.591	NM_003836	DLK1	delta-like 1 homolog (Drosophila)
chr17_+_7554415	12.586		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr1_+_2005083	12.577	NM_001033581	PRKCZ	protein kinase C, zeta
chr19_+_35634153	12.534	NM_022006	FXYD7	FXYD domain containing ion transport regulator 7
chr12_+_117176085	12.511	NM_001109903 NM_032814	RNFT2	ring finger protein, transmembrane 2
chr19_+_45417576	12.479		APOC1	apolipoprotein C-I
chrX_+_102000906	12.413	NM_001142529 NM_001142530	BHLHB9	basic helix-loop-helix domain containing, class B, 9
chrX_-_140271275	12.371		LDOC1	leucine zipper, down-regulated in cancer 1
chr11_+_65554504	12.310	NM_004561	OVOL1	ovo-like 1(Drosophila)
chr6_-_110500803	12.307		WASF1	WAS protein family, member 1
chr20_+_24450269	12.306		SYNDIG1	synapse differentiation inducing 1
chr19_+_7694658	12.260	NM_001171155	C19orf79	chromosome 19 open reading frame 79
chr8_+_19796581	12.170	NM_000237	LPL	lipoprotein lipase
chr5_-_168727715	12.153	NM_003062	SLIT3	slit homolog 3 (Drosophila)
chr4_-_176734181	12.080	NM_201591	GPM6A	glycoprotein M6A
chrX_-_48931645	12.057	NM_007213	PRAF2	PRA1 domain family, member 2
chr4_+_72052354	11.999	NM_001098484 NM_001134742	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr4_-_174450529	11.938		HAND2	heart and neural crest derivatives expressed 2
chr7_+_65338161	11.936	NM_173517	VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr21_-_33104210	11.934		SCAF4	SR-related CTD-associated factor 4
chr20_+_42143045	11.930	NM_015478	L3MBTL1	l(3)mbt-like 1 (Drosophila)
chr4_-_5890266	11.870	NM_001313	CRMP1	collapsin response mediator protein 1
chr4_-_102267952	11.789		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr16_-_74401991	11.772		LOC283922	pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
chr10_+_52751114	11.763		PRKG1	protein kinase, cGMP-dependent, type I
chr1_+_2005424	11.685	NM_001242874	PRKCZ	protein kinase C, zeta
chr7_-_123388711	11.652	NM_003941	WASL	Wiskott-Aldrich syndrome-like
chr5_-_851100	11.643	NM_024786	ZDHHC11	zinc finger, DHHC-type containing 11
chr9_+_124061880	11.608	NM_000177	GSN	gelsolin
chr3_-_9885695	11.544	NM_001142547 NM_173659	RPUSD3	RNA pseudouridylate synthase domain containing 3
chr1_+_36690038	11.539		THRAP3	thyroid hormone receptor associated protein 3
chr17_+_7554711	11.401		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr17_+_7608413	11.397	NM_001406	EFNB3	ephrin-B3
chr11_+_64851731	11.370		ZFPL1	zinc finger protein-like 1
chr3_+_101568325	11.292	NM_031419	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr8_+_1922030	11.275	NM_014867	KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr22_-_19511777	11.239		CLDN5	claudin 5
chr19_-_46295785	11.231	NM_004943	DMWD	dystrophia myotonica, WD repeat containing
chr11_-_65640199	11.193	NM_016938	EFEMP2	EGF containing fibulin-like extracellular matrix protein 2
chr14_+_101193275	11.102		DLK1	delta-like 1 homolog (Drosophila)
chr1_-_150602089	11.100	NM_004436 NM_207042 NM_207043 NM_207044 NM_207168	ENSA	endosulfine alpha
chr12_+_79257772	11.056	NM_001135805	SYT1	synaptotagmin I
chr11_+_63606598	11.038		MARK2	MAP/microtubule affinity-regulating kinase 2
chr15_+_45879575	11.037		PLDN	pallidin homolog (mouse)
chr7_-_129251465	10.964
chr2_+_17935379	10.949	NM_001130009	GEN1	Gen endonuclease homolog 1 (Drosophila)
chr6_+_151561508	10.948		AKAP12	A kinase (PRKA) anchor protein 12
chr19_-_49149252	10.920	NM_001217	CA11	carbonic anhydrase XI
chr6_+_41040713	10.865		NFYA	nuclear transcription factor Y, alpha
chr1_+_36689996	10.855	NM_005119	THRAP3	thyroid hormone receptor associated protein 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.49	1.32e-23	GO:0032502	developmental process
1.49	1.88e-22	GO:0023052	signaling
1.27	1.31e-21	GO:0065007	biological regulation
1.53	6.00e-21	GO:0048856	anatomical structure development
1.49	1.48e-20	GO:0007275	multicellular organismal development
1.36	3.00e-20	GO:0032501	multicellular organismal process
1.29	5.80e-20	GO:0050794	regulation of cellular process
1.54	2.26e-19	GO:0048731	system development
1.63	3.38e-18	GO:0048869	cellular developmental process
1.64	7.09e-18	GO:0030154	cell differentiation
1.26	9.83e-18	GO:0050789	regulation of biological process
1.74	5.26e-16	GO:0007399	nervous system development
1.73	9.56e-16	GO:0009653	anatomical structure morphogenesis
1.14	1.92e-14	GO:0009987	cellular process
1.41	9.02e-14	GO:0007165	signal transduction
2.27	1.82e-13	GO:0019226	transmission of nerve impulse
2.27	1.82e-13	GO:0035637	multicellular organismal signaling
1.58	6.01e-11	GO:0023051	regulation of signaling
1.90	6.67e-11	GO:0007267	cell-cell signaling
1.78	2.86e-10	GO:0048468	cell development
2.18	5.27e-10	GO:0007268	synaptic transmission
1.78	1.97e-09	GO:0009888	tissue development
1.30	2.55e-09	GO:0051716	cellular response to stimulus
1.78	2.98e-09	GO:0048699	generation of neurons
1.87	4.73e-09	GO:0030182	neuron differentiation
1.49	4.79e-09	GO:0048513	organ development
1.74	5.09e-09	GO:0022008	neurogenesis
1.39	5.18e-09	GO:0048518	positive regulation of biological process
1.69	7.70e-09	GO:0007154	cell communication
1.41	1.40e-08	GO:0048522	positive regulation of cellular process
1.47	3.33e-08	GO:0048583	regulation of response to stimulus
1.92	3.93e-08	GO:0048666	neuron development
1.55	5.38e-08	GO:0009966	regulation of signal transduction
1.73	6.24e-08	GO:0009891	positive regulation of biosynthetic process
2.65	7.42e-08	GO:0048732	gland development
1.70	7.99e-08	GO:0050793	regulation of developmental process
1.67	1.04e-07	GO:0032879	regulation of localization
1.77	1.35e-07	GO:0010557	positive regulation of macromolecule biosynthetic process
1.72	1.38e-07	GO:0031328	positive regulation of cellular biosynthetic process
2.04	1.42e-07	GO:0048667	cell morphogenesis involved in neuron differentiation
1.57	1.47e-07	GO:0051239	regulation of multicellular organismal process
1.96	1.97e-07	GO:0000904	cell morphogenesis involved in differentiation
1.30	2.70e-07	GO:0031323	regulation of cellular metabolic process
1.86	2.77e-07	GO:0009887	organ morphogenesis
2.04	2.90e-07	GO:0007409	axonogenesis
1.65	3.44e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.36	3.60e-07	GO:0009889	regulation of biosynthetic process
1.41	3.82e-07	GO:0065008	regulation of biological quality
1.62	4.20e-07	GO:0010646	regulation of cell communication
2.17	4.75e-07	GO:0007411	axon guidance
1.36	4.81e-07	GO:0031326	regulation of cellular biosynthetic process
1.55	7.79e-07	GO:0009893	positive regulation of metabolic process
1.27	8.44e-07	GO:0019222	regulation of metabolic process
1.72	9.09e-07	GO:0051173	positive regulation of nitrogen compound metabolic process
1.73	9.18e-07	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52	9.18e-07	GO:0035556	intracellular signal transduction
1.20	9.64e-07	GO:0050896	response to stimulus
1.77	1.08e-06	GO:0010628	positive regulation of gene expression
2.16	1.30e-06	GO:0001501	skeletal system development
1.76	1.35e-06	GO:0009790	embryo development
1.35	1.70e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.55	1.89e-06	GO:0031325	positive regulation of cellular metabolic process
1.78	1.94e-06	GO:0007167	enzyme linked receptor protein signaling pathway
1.96	2.04e-06	GO:0048812	neuron projection morphogenesis
1.29	2.42e-06	GO:0080090	regulation of primary metabolic process
1.88	2.49e-06	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.55	3.30e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.70	3.94e-06	GO:2000026	regulation of multicellular organismal development
1.80	4.06e-06	GO:0000902	cell morphogenesis
1.89	4.32e-06	GO:0030001	metal ion transport
1.77	5.22e-06	GO:0045893	positive regulation of transcription, DNA-dependent
1.63	5.28e-06	GO:0006811	ion transport
1.38	7.09e-06	GO:0048523	negative regulation of cellular process
2.00	1.08e-05	GO:0048598	embryonic morphogenesis
1.86	1.34e-05	GO:0031175	neuron projection development
1.32	1.82e-05	GO:0051171	regulation of nitrogen compound metabolic process
1.41	2.33e-05	GO:0007166	cell surface receptor linked signaling pathway
1.77	2.80e-05	GO:0006812	cation transport
2.02	2.81e-05	GO:0007389	pattern specification process
2.07	3.12e-05	GO:0022603	regulation of anatomical structure morphogenesis
1.33	3.27e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.82	3.30e-05	GO:0048858	cell projection morphogenesis
1.72	3.86e-05	GO:0032989	cellular component morphogenesis
1.69	4.97e-05	GO:0045595	regulation of cell differentiation
1.81	5.11e-05	GO:0032990	cell part morphogenesis
1.34	5.69e-05	GO:0048519	negative regulation of biological process
1.80	5.69e-05	GO:0007417	central nervous system development
1.26	6.05e-05	GO:0051179	localization
2.10	6.80e-05	GO:0035295	tube development
1.33	6.91e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.68	7.32e-05	GO:0051254	positive regulation of RNA metabolic process
1.35	9.14e-05	GO:0006355	regulation of transcription, DNA-dependent
1.26	1.11e-04	GO:0016043	cellular component organization
1.26	1.13e-04	GO:0060255	regulation of macromolecule metabolic process
1.80	1.85e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.57	2.13e-04	GO:0006351	transcription, DNA-dependent
1.76	2.19e-04	GO:0006935	chemotaxis
1.76	2.19e-04	GO:0042330	taxis
1.57	2.26e-04	GO:0040011	locomotion
1.54	2.39e-04	GO:0042127	regulation of cell proliferation
2.04	2.99e-04	GO:0007423	sensory organ development
1.81	3.27e-04	GO:0051094	positive regulation of developmental process
2.73	4.05e-04	GO:0048736	appendage development
2.73	4.05e-04	GO:0060173	limb development
2.44	4.34e-04	GO:0031344	regulation of cell projection organization
2.13	5.53e-04	GO:0051129	negative regulation of cellular component organization
2.74	5.56e-04	GO:0035107	appendage morphogenesis
2.74	5.56e-04	GO:0035108	limb morphogenesis
1.94	5.62e-04	GO:0051093	negative regulation of developmental process
1.99	6.78e-04	GO:0051270	regulation of cellular component movement
1.76	7.77e-04	GO:0072358	cardiovascular system development
1.76	7.77e-04	GO:0072359	circulatory system development
2.69	8.96e-04	GO:0061138	morphogenesis of a branching epithelium
2.11	8.97e-04	GO:0002009	morphogenesis of an epithelium
1.79	9.03e-04	GO:0032583	regulation of gene-specific transcription
1.85	9.33e-04	GO:0009792	embryo development ending in birth or egg hatching
1.31	1.05e-03	GO:0051252	regulation of RNA metabolic process
2.89	1.16e-03	GO:0030879	mammary gland development
2.08	1.16e-03	GO:0003002	regionalization
1.85	1.27e-03	GO:0043009	chordate embryonic development
2.37	1.31e-03	GO:0043062	extracellular structure organization
1.84	1.31e-03	GO:0060429	epithelium development
1.31	1.37e-03	GO:0042221	response to chemical stimulus
1.96	1.39e-03	GO:0001944	vasculature development
1.28	1.42e-03	GO:0010468	regulation of gene expression
2.50	1.55e-03	GO:0001763	morphogenesis of a branching structure
1.62	1.97e-03	GO:0030030	cell projection organization
2.00	2.02e-03	GO:0045596	negative regulation of cell differentiation
1.93	2.16e-03	GO:0048729	tissue morphogenesis
1.96	2.33e-03	GO:0051960	regulation of nervous system development
1.53	2.45e-03	GO:0051128	regulation of cellular component organization
1.23	2.55e-03	GO:0071840	cellular component organization or biogenesis
2.28	2.75e-03	GO:0009952	anterior/posterior pattern formation
1.74	2.78e-03	GO:0055082	cellular chemical homeostasis
1.62	2.93e-03	GO:0048878	chemical homeostasis
1.74	3.05e-03	GO:0023057	negative regulation of signaling
1.93	3.19e-03	GO:0040012	regulation of locomotion
1.74	3.37e-03	GO:0010648	negative regulation of cell communication
1.25	3.89e-03	GO:0051234	establishment of localization
1.56	4.36e-03	GO:0051049	regulation of transport
1.70	4.50e-03	GO:0050801	ion homeostasis
2.70	5.19e-03	GO:0030326	embryonic limb morphogenesis
2.70	5.19e-03	GO:0035113	embryonic appendage morphogenesis
1.73	5.48e-03	GO:0006873	cellular ion homeostasis
2.36	6.09e-03	GO:0060191	regulation of lipase activity
1.80	6.17e-03	GO:0007420	brain development
1.95	6.51e-03	GO:0008361	regulation of cell size
2.94	6.55e-03	GO:0050770	regulation of axonogenesis
1.85	6.60e-03	GO:0060284	regulation of cell development
4.04	7.03e-03	GO:0030516	regulation of axon extension
1.93	7.84e-03	GO:0001568	blood vessel development
2.36	8.54e-03	GO:0048705	skeletal system morphogenesis
2.01	8.78e-03	GO:0048011	nerve growth factor receptor signaling pathway
1.33	9.20e-03	GO:0003008	system process
1.82	1.06e-02	GO:0015672	monovalent inorganic cation transport
1.24	1.08e-02	GO:0006810	transport
1.73	1.08e-02	GO:0009968	negative regulation of signal transduction
1.36	1.28e-02	GO:0065009	regulation of molecular function
3.34	1.39e-02	GO:0010594	regulation of endothelial cell migration
2.82	1.45e-02	GO:0022612	gland morphogenesis
1.80	1.47e-02	GO:0045597	positive regulation of cell differentiation
2.04	1.63e-02	GO:0045664	regulation of neuron differentiation
1.91	1.68e-02	GO:0030334	regulation of cell migration
1.61	1.82e-02	GO:0019725	cellular homeostasis
1.99	1.93e-02	GO:0048514	blood vessel morphogenesis
1.93	1.93e-02	GO:0050767	regulation of neurogenesis
1.25	2.38e-02	GO:0071842	cellular component organization at cellular level
1.88	2.41e-02	GO:2000145	regulation of cell motility
2.17	2.43e-02	GO:0048562	embryonic organ morphogenesis
2.07	2.49e-02	GO:0035239	tube morphogenesis
1.94	2.51e-02	GO:0048568	embryonic organ development
1.62	2.64e-02	GO:0048585	negative regulation of response to stimulus
2.31	2.91e-02	GO:0010975	regulation of neuron projection development
3.46	3.06e-02	GO:0051149	positive regulation of muscle cell differentiation
1.73	3.11e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
4.10	3.13e-02	GO:0043535	regulation of blood vessel endothelial cell migration
1.92	3.23e-02	GO:0006897	endocytosis
1.92	3.23e-02	GO:0010324	membrane invagination
1.45	3.27e-02	GO:0042592	homeostatic process
2.77	3.27e-02	GO:0048638	regulation of developmental growth
1.67	3.30e-02	GO:0060341	regulation of cellular localization
2.25	3.50e-02	GO:0001503	ossification
5.19	3.85e-02	GO:0043536	positive regulation of blood vessel endothelial cell migration
1.42	4.05e-02	GO:0032774	RNA biosynthetic process
1.49	4.15e-02	GO:0007155	cell adhesion
1.49	4.15e-02	GO:0022610	biological adhesion
2.73	4.18e-02	GO:0010721	negative regulation of cell development
2.19	4.84e-02	GO:0050678	regulation of epithelial cell proliferation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.55	4.70e-16	GO:0044459	plasma membrane part
1.60	2.13e-09	GO:0005887	integral to plasma membrane
1.28	2.15e-09	GO:0071944	cell periphery
1.28	2.51e-09	GO:0005886	plasma membrane
1.58	3.81e-09	GO:0031226	intrinsic to plasma membrane
2.74	7.26e-07	GO:0034703	cation channel complex
2.35	7.79e-07	GO:0034702	ion channel complex
1.63	2.23e-04	GO:0030054	cell junction
1.51	4.24e-04	GO:0005626	insoluble fraction
1.71	1.42e-03	GO:0045202	synapse
1.41	1.82e-03	GO:0000267	cell fraction
1.47	2.76e-03	GO:0005624	membrane fraction
1.69	3.33e-03	GO:0043005	neuron projection
1.45	4.26e-03	GO:0042995	cell projection
2.44	1.61e-02	GO:0008076	voltage-gated potassium channel complex
2.44	1.61e-02	GO:0034705	potassium channel complex
1.42	3.00e-02	GO:0031410	cytoplasmic vesicle
1.70	3.41e-02	GO:0044456	synapse part
1.91	3.55e-02	GO:0031252	cell leading edge
1.43	3.69e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
2.60	4.68e-02	GO:0031256	leading edge membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.68	2.92e-09	GO:0001071	nucleic acid binding transcription factor activity
1.68	2.92e-09	GO:0003700	sequence-specific DNA binding transcription factor activity
1.82	6.39e-09	GO:0043565	sequence-specific DNA binding
1.10	7.22e-09	GO:0005488	binding
2.31	3.69e-08	GO:0005261	cation channel activity
1.86	7.35e-08	GO:0008324	cation transmembrane transporter activity
2.73	5.64e-07	GO:0022843	voltage-gated cation channel activity
1.56	2.78e-06	GO:0030528	transcription regulator activity
1.66	3.41e-06	GO:0015075	ion transmembrane transporter activity
1.91	6.89e-06	GO:0005216	ion channel activity
1.15	1.13e-05	GO:0005515	protein binding
1.87	1.21e-05	GO:0015267	channel activity
2.03	1.22e-05	GO:0022836	gated channel activity
1.87	1.36e-05	GO:0022803	passive transmembrane transporter activity
1.89	1.42e-05	GO:0022838	substrate-specific channel activity
2.32	1.90e-05	GO:0005244	voltage-gated ion channel activity
2.32	1.90e-05	GO:0022832	voltage-gated channel activity
1.49	4.86e-04	GO:0022857	transmembrane transporter activity
1.50	6.08e-04	GO:0022891	substrate-specific transmembrane transporter activity
2.88	8.78e-04	GO:0005262	calcium channel activity
2.06	1.48e-03	GO:0000975	regulatory region DNA binding
2.06	1.48e-03	GO:0001067	regulatory region nucleic acid binding
2.06	1.48e-03	GO:0044212	transcription regulatory region DNA binding
3.25	1.51e-03	GO:0004879	ligand-dependent nuclear receptor activity
3.26	2.67e-03	GO:0003707	steroid hormone receptor activity
2.05	2.87e-03	GO:0010843	promoter binding
1.80	3.60e-03	GO:0016563	transcription activator activity
1.60	1.57e-02	GO:0030695	GTPase regulator activity
4.89	1.81e-02	GO:0005212	structural constituent of eye lens
5.28	2.56e-02	GO:0005248	voltage-gated sodium channel activity
2.31	3.90e-02	GO:0005057	receptor signaling protein activity
1.56	4.01e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.37	4.50e-02	GO:0022892	substrate-specific transporter activity
1.72	4.77e-02	GO:0005083	small GTPase regulator activity