Motif ID: ZNF143.p2

Z-value: 5.327


Transcription factors associated with ZNF143.p2:

Gene SymbolEntrez IDGene Name
ZNF143 7702 zinc finger protein 143

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF143chr11_+_94825110.583.6e-21Click!


Activity profile for motif ZNF143.p2.

activity profile for motif ZNF143.p2


Sorted Z-values histogram for motif ZNF143.p2

Sorted Z-values for motif ZNF143.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF143.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_1723212 134.977 NM_006342
 TACC3
transforming, acidic coiled-coil containing protein 3
chr17_-_47492215 128.301 PHB
prohibitin
chr20_-_32891075 116.312 NM_000687
 AHCY
adenosylhomocysteinase
chr12_+_56498324 109.260 PA2G4
proliferation-associated 2G4, 38kDa
chr12_+_56498347 107.642 PA2G4
proliferation-associated 2G4, 38kDa
chr15_+_40453263 107.174 BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr15_+_40453209 104.125 NM_001211
 BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr19_-_48673559 101.616 NM_000234
 LIG1
ligase I, DNA, ATP-dependent
chr12_+_32832128 96.640 NM_005690
NM_012062
NM_012063
 DNM1L


dynamin 1-like


chr1_-_54304107 96.112 NM_001168551
NM_018087
 TMEM48

transmembrane protein 48

chrY_+_59213948 95.454 NM_001145149
NM_001185183
NM_005638
 VAMP7


vesicle-associated membrane protein 7


chrX_+_155110942 93.306 NM_001145149
NM_001185183
NM_005638
 VAMP7


vesicle-associated membrane protein 7


chr12_+_56498102 90.909 NM_006191
 PA2G4
proliferation-associated 2G4, 38kDa
chr17_-_47492216 89.496 NM_002634
 PHB
prohibitin
chr11_-_82997376 89.069 NM_021825
 CCDC90B
coiled-coil domain containing 90B
chr12_+_56498414 87.077 PA2G4
proliferation-associated 2G4, 38kDa
chr12_+_32832209 80.578 DNM1L
dynamin 1-like
chr4_+_1723233 80.417 TACC3
transforming, acidic coiled-coil containing protein 3
chr11_-_82996898 80.222 CCDC90B
coiled-coil domain containing 90B
chr10_+_124913884 79.841 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 156 entries
enrichment   p-value GO term description
6.01 3.77e-05 GO:0000245 spliceosome assembly
4.19 2.09e-06 GO:0022618 ribonucleoprotein complex assembly
4.18 1.53e-02 GO:0042773 ATP synthesis coupled electron transport
4.18 1.53e-02 GO:0042775 mitochondrial ATP synthesis coupled electron transport
4.12 1.47e-06 GO:0071826 ribonucleoprotein complex subunit organization
4.05 1.03e-04 GO:0051352 negative regulation of ligase activity
4.05 1.03e-04 GO:0051444 negative regulation of ubiquitin-protein ligase activity
4.05 1.06e-02 GO:0006119 oxidative phosphorylation
4.01 2.53e-04 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.99 2.87e-05 GO:0000216 M/G1 transition of mitotic cell cycle
3.86 9.26e-03 GO:0046782 regulation of viral transcription
3.74 1.74e-13 GO:0000375 RNA splicing, via transesterification reactions
3.72 2.40e-04 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
3.71 7.81e-03 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
3.71 7.81e-03 GO:0072395 signal transduction involved in cell cycle checkpoint
3.71 7.81e-03 GO:0072401 signal transduction involved in DNA integrity checkpoint
3.71 7.81e-03 GO:0072404 signal transduction involved in G1/S transition checkpoint
3.71 7.81e-03 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
3.71 7.81e-03 GO:0072422 signal transduction involved in DNA damage checkpoint
3.71 7.81e-03 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint

Gene overrepresentation in compartment category:

Showing 1 to 20 of 63 entries
enrichment   p-value GO term description
7.72 1.91e-02 GO:0005732 small nucleolar ribonucleoprotein complex
5.66 1.70e-03 GO:0044452 nucleolar part
4.12 1.40e-06 GO:0071013 catalytic step 2 spliceosome
3.90 8.70e-05 GO:0005643 nuclear pore
3.74 1.81e-04 GO:0000777 condensed chromosome kinetochore
3.74 5.94e-03 GO:0015935 small ribosomal subunit
3.70 3.65e-09 GO:0005681 spliceosomal complex
3.68 1.19e-04 GO:0000779 condensed chromosome, centromeric region
3.60 2.54e-03 GO:0000502 proteasome complex
3.43 4.84e-03 GO:0070469 respiratory chain
3.41 4.39e-04 GO:0046930 pore complex
3.25 5.60e-03 GO:0022626 cytosolic ribosome
3.22 1.17e-03 GO:0000776 kinetochore
3.06 1.42e-05 GO:0000793 condensed chromosome
3.01 3.56e-22 GO:0030529 ribonucleoprotein complex
2.95 3.95e-04 GO:0044455 mitochondrial membrane part
2.65 7.52e-05 GO:0005840 ribosome
2.61 1.21e-03 GO:0044445 cytosolic part
2.53 4.77e-04 GO:0005819 spindle
2.49 9.16e-03 GO:0000775 chromosome, centromeric region

Gene overrepresentation in function category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
14.16 1.46e-02 GO:0030911 TPR domain binding
9.44 5.10e-03 GO:0008139 nuclear localization sequence binding
5.79 5.48e-03 GO:0005048 signal sequence binding
3.95 1.74e-02 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
3.08 5.17e-06 GO:0003735 structural constituent of ribosome
2.88 2.11e-03 GO:0051082 unfolded protein binding
2.04 1.80e-10 GO:0003723 RNA binding
1.64 2.39e-03 GO:0016462 pyrophosphatase activity
1.63 2.81e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.63 3.29e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.62 5.99e-03 GO:0017111 nucleoside-triphosphatase activity
1.52 1.16e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.52 5.65e-05 GO:0005524 ATP binding
1.50 2.34e-06 GO:0017076 purine nucleotide binding
1.50 2.52e-06 GO:0032553 ribonucleotide binding
1.50 2.52e-06 GO:0032555 purine ribonucleotide binding
1.50 8.90e-05 GO:0032559 adenyl ribonucleotide binding
1.50 1.26e-04 GO:0030554 adenyl nucleotide binding
1.48 2.11e-07 GO:0000166 nucleotide binding
1.41 6.18e-30 GO:0005515 protein binding