Motif ID: ZNF238.p2

Z-value: 1.251


Transcription factors associated with ZNF238.p2:

Gene SymbolEntrez IDGene Name
ZNF238 10472 zinc finger protein 238

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF238chr1_+_244216506-0.342.3e-07Click!


Activity profile for motif ZNF238.p2.

activity profile for motif ZNF238.p2


Sorted Z-values histogram for motif ZNF238.p2

Sorted Z-values for motif ZNF238.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF238.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_55512801 62.734 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr2_+_189839132 42.948 COL3A1
collagen, type III, alpha 1
chr2_+_189839113 38.788 COL3A1
collagen, type III, alpha 1
chr2_+_189839078 38.206 NM_000090
COL3A1
collagen, type III, alpha 1
chr1_-_17307107 14.757 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr15_-_90358057 14.245 NM_001150
ANPEP
alanyl (membrane) aminopeptidase
chr3_+_100211408 14.030 NM_018004
TMEM45A
transmembrane protein 45A
chr19_-_11305186 13.940 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr3_+_100211554 13.457 TMEM45A
transmembrane protein 45A
chr17_+_47653474 13.457 NXPH3
neurexophilin 3
chr16_-_65155881 13.202 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr3_+_30647901 12.914 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr2_-_163099877 12.882 NM_004460
FAP
fibroblast activation protein, alpha
chr19_+_11649578 12.664 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr16_-_65155984 11.859 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_-_203320249 11.307


chr16_-_65155965 11.303 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_-_203320287 10.631 NM_002023
FMOD
fibromodulin
chr17_+_47653176 10.546 NM_007225
NXPH3
neurexophilin 3
chr1_-_203320185 10.349 FMOD
fibromodulin
chr17_+_77020278 10.194 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr2_+_135676409 10.041 CCNT2
cyclin T2
chr14_+_94577078 9.819 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr5_-_178772328 9.757 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr1_+_212781969 9.731 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr17_+_77020229 9.581 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chrX_-_107018889 9.523 TSC22D3
TSC22 domain family, member 3
chr1_+_212782103 9.515 ATF3
activating transcription factor 3
chr11_+_75273245 9.347 SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr11_+_75273100 9.047 NM_001207014
NM_001235
SERPINH1

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

chr5_-_178772430 8.600 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr6_-_163148798 7.803 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr3_+_30648372 7.730 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr1_-_16344438 7.726 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr12_-_104443698 7.452 GLT8D2
glycosyltransferase 8 domain containing 2
chrX_-_107019001 7.361 NM_198057
TSC22D3
TSC22 domain family, member 3
chr1_-_168698412 7.235 NM_001937
DPT
dermatopontin
chrX_+_13587693 7.094 NM_001167890
NM_015507
EGFL6

EGF-like-domain, multiple 6

chr12_-_104443914 6.933 NM_031302
GLT8D2
glycosyltransferase 8 domain containing 2
chr11_+_76494132 6.929 NM_015516
TSKU
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chrX_+_99899162 6.551 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr9_+_116263706 6.278 NM_130795
RGS3
regulator of G-protein signaling 3
chrX_+_99899388 6.227 SRPX2
sushi-repeat containing protein, X-linked 2
chr11_+_10326618 6.040 NM_001124
ADM
adrenomedullin
chr11_-_119252267 5.648 USP2
ubiquitin specific peptidase 2
chr10_-_123357503 5.629 NM_000141
NM_001144917
NM_001144918
NM_001144919
NM_022970
FGFR2




fibroblast growth factor receptor 2




chr6_-_163148800 5.624 NM_004562
NM_013987
NM_013988
PARK2


parkinson protein 2, E3 ubiquitin protein ligase (parkin)


chr17_-_15168590 5.616 NM_000304
PMP22
peripheral myelin protein 22
chr11_+_46299554 5.603 CREB3L1
cAMP responsive element binding protein 3-like 1
chr6_+_163149001 5.580 NM_001080379
PACRG
PARK2 co-regulated
chr8_-_49833823 5.256 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr15_+_31619043 5.244 NM_015995
KLF13
Kruppel-like factor 13
chr17_+_60705042 5.133 MRC2
mannose receptor, C type 2
chr17_-_67138013 5.039 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr22_+_21271940 5.006 CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr6_-_30523502 4.813 GNL1
guanine nucleotide binding protein-like 1
chr8_-_11705259 4.762


chr12_+_112563359 4.712 TRAFD1
TRAF-type zinc finger domain containing 1
chr2_-_1748240 4.704 PXDN
peroxidasin homolog (Drosophila)
chr2_+_219246751 4.629 NM_000578
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr2_+_152214105 4.535 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr7_+_45197366 4.379 NM_005856
RAMP3
receptor (G protein-coupled) activity modifying protein 3
chr17_+_32612686 4.377 NM_002986
CCL11
chemokine (C-C motif) ligand 11
chr12_-_54813002 4.348 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr9_-_129884998 4.309 NM_012098
ANGPTL2
angiopoietin-like 2
chr15_+_40331417 4.271 LOC100131089
uncharacterized LOC100131089
chr7_+_90225607 4.250 CDK14
cyclin-dependent kinase 14
chr17_+_60705051 4.195 MRC2
mannose receptor, C type 2
chr22_+_38071612 4.169 NM_002305
LGALS1
lectin, galactoside-binding, soluble, 1
chr5_-_151304322 4.156 NM_000171
NM_001146040
GLRA1

glycine receptor, alpha 1

chr5_+_15500288 4.150 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr7_+_154862545 4.130 NM_024012
HTR5A
5-hydroxytryptamine (serotonin) receptor 5A
chr11_+_46299585 4.102 CREB3L1
cAMP responsive element binding protein 3-like 1
chr10_-_105212149 4.020 NM_015916
CALHM2
calcium homeostasis modulator 2
chr21_-_35883570 3.986 NM_000219
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr17_+_19282058 3.965 MAPK7
mitogen-activated protein kinase 7
chr2_+_201473942 3.934 AOX1
aldehyde oxidase 1
chr12_-_54813010 3.922 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_143744355 3.853 LOC100286793
FLJ39739
uncharacterized LOC100286793
uncharacterized FLJ39739
chr15_-_74502045 3.837 NM_001199040
STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chrX_+_99839789 3.788 NM_022144
TNMD
tenomodulin
chr1_-_220263104 3.748 BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr19_-_44174497 3.748 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr15_-_74501309 3.737 NM_001142617
NM_001142619
NM_001142620
STRA6


stimulated by retinoic acid gene 6 homolog (mouse)


chr12_-_91573264 3.729 NM_133503
DCN
decorin
chr2_-_25466795 3.726 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr5_-_64777703 3.684 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr11_-_2159784 3.662 IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_-_129884961 3.586 ANGPTL2
angiopoietin-like 2
chr2_-_1748285 3.555 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr4_-_155533800 3.548 FGG
fibrinogen gamma chain
chr11_+_64323089 3.536 NM_018484
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr1_-_153518265 3.506 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr6_-_30523933 3.492 GNL1
guanine nucleotide binding protein-like 1
chr6_-_39197225 3.441 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr2_-_25467078 3.432 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr5_-_39425030 3.428 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr17_-_53809444 3.412 NM_001099640
TMEM100
transmembrane protein 100
chr3_+_124303505 3.398 NM_007064
KALRN
kalirin, RhoGEF kinase
chr12_-_48119224 3.376 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chrX_+_48242967 3.368 NM_001034832
NM_001040612
NM_005636
NM_175729
SSX4B

SSX4

synovial sarcoma, X breakpoint 4B

synovial sarcoma, X breakpoint 4

chr1_-_220263150 3.367 NM_006085
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr11_-_30038487 3.297 NM_002233
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr15_+_94899163 3.294 NM_001159644
MCTP2
multiple C2 domains, transmembrane 2
chr19_-_44174271 3.289 PLAUR
plasminogen activator, urokinase receptor
chr12_-_54812936 3.287 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_201476248 3.274 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chrX_+_43515406 3.205 NM_000240
MAOA
monoamine oxidase A
chr4_+_47487230 3.177 NM_020453
ATP10D
ATPase, class V, type 10D
chr18_-_52969714 3.160 NM_001243236
TCF4
transcription factor 4
chr8_+_17354562 3.091 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr4_+_156824846 3.062 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr12_-_108733075 3.012 NM_001142343
NM_001142344
NM_004072
CMKLR1


chemokine-like receptor 1


chr7_+_127292152 2.973 NM_014390
SND1
staphylococcal nuclease and tudor domain containing 1
chr17_+_32597239 2.970 NM_006273
CCL7
chemokine (C-C motif) ligand 7
chr3_-_121379701 2.943 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr7_+_127292245 2.936 SND1
staphylococcal nuclease and tudor domain containing 1
chr13_+_49280619 2.929 NM_020377
CYSLTR2
cysteinyl leukotriene receptor 2
chr11_+_130029773 2.924 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr11_+_46299161 2.920 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr2_-_1748317 2.918 PXDN
peroxidasin homolog (Drosophila)
chr14_-_106746056 2.917


chr20_+_30063090 2.907 NM_014012
REM1
RAS (RAD and GEM)-like GTP-binding 1
chr12_+_13349720 2.903 EMP1
epithelial membrane protein 1
chr1_-_201476241 2.874 CSRP1
cysteine and glycine-rich protein 1
chr12_-_102874158 2.869 IGF1
insulin-like growth factor 1 (somatomedin C)
chrX_+_43515441 2.863 MAOA
monoamine oxidase A
chr2_+_33359607 2.856 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr1_+_14075931 2.834 PRDM2
PR domain containing 2, with ZNF domain
chr4_-_72669757 2.804 NM_001204307
GC
group-specific component (vitamin D binding protein)
chr6_+_160542862 2.798 NM_003057
NM_153187
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr11_-_83984230 2.781 NM_001142700
DLG2
discs, large homolog 2 (Drosophila)
chrY_-_2655478 2.761 NM_003140
SRY
sex determining region Y
chr4_+_93225549 2.743 NM_001510
GRID2
glutamate receptor, ionotropic, delta 2
chr13_+_97928196 2.733 MBNL2
muscleblind-like 2 (Drosophila)
chr1_-_156647088 2.711 NM_006617
NES
nestin
chrX_-_38186782 2.682 NM_000328
NM_001034853
RPGR

retinitis pigmentosa GTPase regulator

chr1_+_19972259 2.678 NM_001204086
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr19_+_15852200 2.676 NM_013938
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr12_-_110252600 2.651 NM_001177431
NM_001177428
NM_001177433
NM_147204
TRPV4



transient receptor potential cation channel, subfamily V, member 4



chr6_+_7108864 2.643 RREB1
ras responsive element binding protein 1
chr11_+_1889902 2.642 NM_001013253
LSP1
lymphocyte-specific protein 1
chr4_-_155533757 2.626 FGG
fibrinogen gamma chain
chr16_-_70099755 2.585 PDXDC2P
pyridoxal-dependent decarboxylase domain containing 2, pseudogene
chr11_-_2159472 2.583 IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_201476218 2.558 CSRP1
cysteine and glycine-rich protein 1
chrX_+_43515531 2.539 MAOA
monoamine oxidase A
chr14_-_61748510 2.536 NM_001017970
TMEM30B
transmembrane protein 30B
chr19_+_2328628 2.532 NM_001077238
NM_152988
SPPL2B

signal peptide peptidase-like 2B

chr6_+_111408780 2.507 NM_018593
SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr14_-_21271002 2.506 NM_002933
NM_198234
NM_198235
RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chrX_-_38186619 2.501 RPGR
retinitis pigmentosa GTPase regulator
chr16_+_28891234 2.471 ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr11_-_67442018 2.465 ALDH3B2
aldehyde dehydrogenase 3 family, member B2
chr9_+_21440452 2.425 NM_024013
IFNA1
interferon, alpha 1
chr12_+_26348268 2.420 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr19_-_15918848 2.381 NM_013940
OR10H1
olfactory receptor, family 10, subfamily H, member 1
chr4_-_111563278 2.358 NM_001204397
NM_001204398
NM_001204399
NM_153426
NM_153427
PITX2




paired-like homeodomain 2




chr10_-_104001229 2.351 NM_005029
PITX3
paired-like homeodomain 3
chr9_-_21368005 2.326 NM_006900
IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr17_-_9939873 2.323 GAS7
growth arrest-specific 7
chr1_-_217263195 2.311 NM_001243505
ESRRG
estrogen-related receptor gamma
chr3_-_114102488 2.303 NM_001164342
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_161551128 2.303 NM_201563
FCGR2C
Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr11_-_2159925 2.274 IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_113885137 2.248 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr11_-_5173598 2.238 NM_012375
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr20_+_57875647 2.217 EDN3
endothelin 3
chr21_+_46875402 2.213 NM_030582
COL18A1
collagen, type XVIII, alpha 1
chr7_+_102074002 2.213 ORAI2
ORAI calcium release-activated calcium modulator 2
chr1_+_24069961 2.186 TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr19_+_2328679 2.164 SPPL2B
signal peptide peptidase-like 2B
chr14_+_64971417 2.159 ZBTB1
zinc finger and BTB domain containing 1
chr19_+_7828034 2.158 NM_001144904
NM_001144905
NM_001144906
NM_001144907
NM_001144908
NM_001144909
NM_001144910
NM_001144911
NM_014257
CLEC4M








C-type lectin domain family 4, member M








chr5_+_49962771 2.155 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr1_-_171621750 2.116 NM_000261
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response
chr17_-_42345434 2.113 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr17_+_64960754 2.111 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr2_-_211018294 2.111 C2orf67
chromosome 2 open reading frame 67
chr4_-_155533850 2.082 FGG
fibrinogen gamma chain
chr14_-_77737549 2.076 NM_021257
NGB
neuroglobin
chr5_+_49962920 2.052 PARP8
poly (ADP-ribose) polymerase family, member 8
chr5_+_140782367 2.049 NM_018921
NM_032089
PCDHGA9

protocadherin gamma subfamily A, 9

chr11_-_17498322 2.022 ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr5_-_39424930 2.007 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_+_204042191 1.992 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr12_+_112563293 1.984 NM_001143906
NM_006700
TRAFD1

TRAF-type zinc finger domain containing 1

chr15_-_55611289 1.965


chr4_-_121843668 1.964 NM_018699
PRDM5
PR domain containing 5
chr3_-_121379757 1.962 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr9_+_124030455 1.946 GSN
gelsolin
chr1_-_153321021 1.942 NM_020393
PGLYRP4
peptidoglycan recognition protein 4
chr11_+_71900601 1.919 NM_016724
NM_016725
FOLR1

folate receptor 1 (adult)

chr1_+_24069855 1.869 NM_003198
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr17_+_14204326 1.864 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr4_+_87856152 1.845 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr15_-_60690115 1.843 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr13_+_113777112 1.820 NM_000504
F10
coagulation factor X
chr3_-_52273031 1.805 TWF2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chr10_-_71332992 1.803 NM_020999
NEUROG3
neurogenin 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.43 9.33e-08 GO:0050896 response to stimulus
2.48 5.29e-07 GO:0009611 response to wounding
1.59 1.26e-06 GO:0023052 signaling
1.30 1.82e-05 GO:0065007 biological regulation
1.58 2.52e-05 GO:0007165 signal transduction
1.31 3.46e-05 GO:0050789 regulation of biological process
1.42 3.77e-05 GO:0032501 multicellular organismal process
1.51 1.28e-04 GO:0032502 developmental process
3.39 1.91e-04 GO:0006954 inflammatory response
1.53 2.46e-04 GO:0007275 multicellular organismal development
1.89 2.89e-04 GO:0009653 anatomical structure morphogenesis
1.70 4.15e-04 GO:0065008 regulation of biological quality
1.93 6.98e-04 GO:0051239 regulation of multicellular organismal process
1.57 7.27e-04 GO:0048731 system development
1.44 7.62e-04 GO:0051716 cellular response to stimulus
1.94 9.55e-04 GO:0002376 immune system process
1.53 9.87e-04 GO:0048856 anatomical structure development
1.29 1.24e-03 GO:0050794 regulation of cellular process
2.22 1.95e-03 GO:0006955 immune response
3.55 3.23e-03 GO:0072507 divalent inorganic cation homeostasis
6.32 5.71e-03 GO:0007229 integrin-mediated signaling pathway
3.49 7.68e-03 GO:0055074 calcium ion homeostasis
1.15 1.01e-02 GO:0009987 cellular process
2.26 1.14e-02 GO:0048878 chemical homeostasis
1.65 1.20e-02 GO:0048583 regulation of response to stimulus
2.81 1.51e-02 GO:0001501 skeletal system development
3.81 1.67e-02 GO:0002237 response to molecule of bacterial origin
1.99 2.27e-02 GO:0009888 tissue development
1.56 2.29e-02 GO:0042221 response to chemical stimulus
3.91 2.42e-02 GO:0032496 response to lipopolysaccharide
1.62 2.73e-02 GO:0048513 organ development
3.18 2.77e-02 GO:0048514 blood vessel morphogenesis
3.85 2.89e-02 GO:0048589 developmental growth
3.29 3.00e-02 GO:0072503 cellular divalent inorganic cation homeostasis
1.90 3.15e-02 GO:0009605 response to external stimulus
5.89 3.20e-02 GO:0040014 regulation of multicellular organism growth
1.53 3.28e-02 GO:0048519 negative regulation of biological process
20.58 3.33e-02 GO:0060558 regulation of calcidiol 1-monooxygenase activity
36.01 3.69e-02 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity
2.89 3.78e-02 GO:0001568 blood vessel development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.75 2.73e-13 GO:0044421 extracellular region part
2.10 2.64e-12 GO:0005576 extracellular region
2.90 2.01e-11 GO:0005615 extracellular space
2.20 3.84e-08 GO:0031226 intrinsic to plasma membrane
2.21 4.24e-08 GO:0005887 integral to plasma membrane
1.79 6.79e-07 GO:0044459 plasma membrane part
3.09 6.27e-06 GO:0031012 extracellular matrix
1.46 1.99e-05 GO:0005886 plasma membrane
3.18 2.91e-05 GO:0005578 proteinaceous extracellular matrix
1.44 5.22e-05 GO:0071944 cell periphery
4.30 2.23e-04 GO:0043235 receptor complex
2.03 2.08e-03 GO:0005624 membrane fraction
1.96 4.54e-03 GO:0005626 insoluble fraction
1.77 1.14e-02 GO:0000267 cell fraction
2.37 2.07e-02 GO:0009986 cell surface
1.20 2.13e-02 GO:0016020 membrane
1.27 2.72e-02 GO:0016021 integral to membrane
1.26 3.83e-02 GO:0031224 intrinsic to membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.64 5.55e-04 GO:0004871 signal transducer activity
1.64 5.55e-04 GO:0060089 molecular transducer activity
3.60 9.94e-04 GO:0005126 cytokine receptor binding
1.69 1.62e-03 GO:0004872 receptor activity
1.93 1.87e-03 GO:0005102 receptor binding
3.60 1.88e-03 GO:0017171 serine hydrolase activity
2.64 2.53e-03 GO:0004175 endopeptidase activity
3.75 4.09e-03 GO:0004252 serine-type endopeptidase activity
7.20 4.17e-03 GO:0003823 antigen binding
3.45 6.08e-03 GO:0008236 serine-type peptidase activity