Motif ID: ZNF423.p2

Z-value: 1.398


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF423chr16_-_498609170.135.6e-02Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_27952591 22.541 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chrX_-_107019001 17.698 NM_198057
TSC22D3
TSC22 domain family, member 3
chr14_+_92790151 17.334 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr19_+_45971249 16.861 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr1_+_26644458 15.928 CD52
CD52 molecule
chr10_+_99079017 15.701 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr5_+_150400132 14.052 GPX3
glutathione peroxidase 3 (plasma)
chr9_+_93564063 13.987 SYK
spleen tyrosine kinase
chr9_+_93564099 13.920 SYK
spleen tyrosine kinase
chr3_+_52529351 13.549 NM_015136
STAB1
stabilin 1
chr3_+_52529370 13.521 STAB1
stabilin 1
chr9_+_93564073 13.474 SYK
spleen tyrosine kinase
chr5_+_150399980 13.210 NM_002084
GPX3
glutathione peroxidase 3 (plasma)
chr16_+_70148213 12.494 PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr9_+_93564204 12.020 NM_001174168
SYK
spleen tyrosine kinase
chr12_+_54332575 11.939 NM_017410
HOXC13
homeobox C13
chr19_-_2041862 11.914 MKNK2
MAP kinase interacting serine/threonine kinase 2
chrX_-_102319080 11.899 BEX1
brain expressed, X-linked 1
chr2_-_145274916 11.682 ZEB2
zinc finger E-box binding homeobox 2
chr8_-_133492556 11.557 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 38 entries
enrichment   p-value GO term description
2.59 2.75e-02 GO:0060627 regulation of vesicle-mediated transport
2.06 6.84e-03 GO:0071495 cellular response to endogenous stimulus
2.02 3.10e-02 GO:0032870 cellular response to hormone stimulus
1.87 2.87e-02 GO:0040008 regulation of growth
1.73 6.00e-03 GO:0009719 response to endogenous stimulus
1.68 1.35e-02 GO:0002682 regulation of immune system process
1.56 1.36e-02 GO:0009605 response to external stimulus
1.55 2.23e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.53 3.02e-04 GO:0009653 anatomical structure morphogenesis
1.50 1.31e-03 GO:0007399 nervous system development
1.48 1.69e-02 GO:0051239 regulation of multicellular organismal process
1.47 3.69e-04 GO:0007166 cell surface receptor linked signaling pathway
1.40 1.94e-03 GO:0048869 cellular developmental process
1.40 7.71e-03 GO:0048583 regulation of response to stimulus
1.39 4.59e-04 GO:0048519 negative regulation of biological process
1.39 8.31e-04 GO:0042221 response to chemical stimulus
1.39 1.98e-03 GO:0048523 negative regulation of cellular process
1.39 2.28e-03 GO:0065008 regulation of biological quality
1.39 4.04e-03 GO:0030154 cell differentiation
1.37 2.95e-07 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.74 4.30e-02 GO:0045202 synapse
1.47 4.46e-07 GO:0044459 plasma membrane part
1.47 4.12e-03 GO:0005887 integral to plasma membrane
1.44 9.90e-03 GO:0031226 intrinsic to plasma membrane
1.25 6.22e-04 GO:0005886 plasma membrane
1.24 9.75e-04 GO:0071944 cell periphery
1.12 2.60e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
4.14 1.10e-02 GO:0003823 antigen binding
2.52 6.80e-03 GO:0022843 voltage-gated cation channel activity
1.78 4.96e-04 GO:0004672 protein kinase activity
1.72 3.70e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.67 6.18e-04 GO:0016301 kinase activity
1.67 2.04e-02 GO:0008324 cation transmembrane transporter activity
1.63 1.10e-02 GO:0043565 sequence-specific DNA binding
1.62 5.68e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.60 9.83e-03 GO:0015075 ion transmembrane transporter activity
1.56 3.27e-02 GO:0019899 enzyme binding
1.50 1.70e-02 GO:0001071 nucleic acid binding transcription factor activity
1.50 1.70e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.35 2.97e-02 GO:0016740 transferase activity
1.19 6.28e-06 GO:0005515 protein binding
1.08 7.83e-03 GO:0005488 binding