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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AAUGCCC

Z-value: 0.35

Motif logo

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miRNA associated with seed AAUGCCC

NamemiRBASE accession
hsa-miR-365a-3p
MIMAT0000710
hsa-miR-365b-3p
MIMAT0022834

Activity profile of AAUGCCC motif

Sorted Z-values of AAUGCCC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_153574480 1.62 ENST00000410080.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr3_+_23986748 1.61 ENST00000312521.4
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr21_-_28217721 1.46 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr3_-_55523966 1.37 ENST00000474267.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr3_-_33481835 1.34 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr3_+_113775576 1.15 ENST00000485050.1
ENST00000281273.4
QTRTD1
queuine tRNA-ribosyltransferase domain containing 1
chr12_-_15942309 1.08 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr12_+_72666407 0.99 ENST00000261180.4
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr17_-_78009647 0.94 ENST00000310924.2
TBC1D16
TBC1 domain family, member 16
chr12_+_66217911 0.91 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr19_+_46850251 0.88 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr5_+_112312416 0.87 ENST00000389063.2
DCP2
decapping mRNA 2
chr12_+_68042495 0.82 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr1_+_2160134 0.81 ENST00000378536.4
SKI
v-ski avian sarcoma viral oncogene homolog
chr4_-_74124502 0.81 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ANKRD17
ankyrin repeat domain 17
chr16_+_67063036 0.80 ENST00000290858.6
ENST00000564034.1
CBFB
core-binding factor, beta subunit
chr9_-_14314066 0.77 ENST00000397575.3
NFIB
nuclear factor I/B
chr3_+_171758344 0.73 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr6_-_134639180 0.72 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr1_-_22109682 0.71 ENST00000400301.1
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chr9_-_117880477 0.71 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
TNC
tenascin C
chr9_+_114659046 0.66 ENST00000374279.3
UGCG
UDP-glucose ceramide glucosyltransferase
chr3_-_79068594 0.66 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr12_-_31479045 0.65 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr3_-_113465065 0.64 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr3_-_123603137 0.63 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK
myosin light chain kinase
chr11_-_31839488 0.63 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6
paired box 6
chrX_-_109561294 0.61 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr2_-_64881018 0.61 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr1_-_153588334 0.59 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chrX_+_77359671 0.59 ENST00000373316.4
PGK1
phosphoglycerate kinase 1
chr1_-_155881156 0.55 ENST00000539040.1
ENST00000368323.3
RIT1
Ras-like without CAAX 1
chr6_-_111804393 0.55 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr3_-_47823298 0.51 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr5_-_43313574 0.51 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr2_-_208634287 0.50 ENST00000295417.3
FZD5
frizzled family receptor 5
chr16_+_53088885 0.50 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr5_+_133861790 0.49 ENST00000395003.1
PHF15
jade family PHD finger 2
chr2_-_183903133 0.48 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr12_-_75905374 0.48 ENST00000438169.2
ENST00000229214.4
KRR1
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr2_+_46926048 0.47 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr10_-_98346801 0.47 ENST00000371142.4
TM9SF3
transmembrane 9 superfamily member 3
chr2_-_200322723 0.46 ENST00000417098.1
SATB2
SATB homeobox 2
chr5_+_74632993 0.46 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr1_-_205719295 0.43 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr15_+_96873921 0.41 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_-_244013384 0.40 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr9_+_131445928 0.39 ENST00000372692.4
SET
SET nuclear oncogene
chr7_-_27205136 0.38 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr11_+_2466218 0.38 ENST00000155840.5
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr20_+_56884752 0.37 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr8_+_54764346 0.36 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr7_-_32931387 0.36 ENST00000304056.4
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr14_+_55518349 0.35 ENST00000395468.4
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr8_-_57123815 0.35 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr1_+_36396677 0.33 ENST00000373191.4
ENST00000397828.2
AGO3
argonaute RISC catalytic component 3
chr1_-_38325256 0.33 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr11_-_27528301 0.33 ENST00000524596.1
ENST00000278193.2
LIN7C
lin-7 homolog C (C. elegans)
chr12_+_56137064 0.31 ENST00000257868.5
ENST00000546799.1
GDF11
growth differentiation factor 11
chr7_+_138145076 0.30 ENST00000343526.4
TRIM24
tripartite motif containing 24
chrX_+_23352133 0.29 ENST00000379361.4
PTCHD1
patched domain containing 1
chr11_+_64073699 0.29 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr10_+_22610124 0.29 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr3_-_15901278 0.28 ENST00000399451.2
ANKRD28
ankyrin repeat domain 28
chr18_-_60987220 0.28 ENST00000398117.1
BCL2
B-cell CLL/lymphoma 2
chr3_-_125094093 0.28 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
ZNF148
zinc finger protein 148
chr7_-_83824169 0.27 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_11762202 0.26 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4
vestigial like 4 (Drosophila)
chr19_-_49576198 0.25 ENST00000221444.1
KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
chr11_+_34642656 0.25 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr17_-_16118835 0.24 ENST00000582357.1
ENST00000436828.1
ENST00000411510.1
ENST00000268712.3
NCOR1
nuclear receptor corepressor 1
chr1_+_29063271 0.24 ENST00000373812.3
YTHDF2
YTH domain family, member 2
chr10_-_105615164 0.23 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr15_+_52121822 0.23 ENST00000558455.1
ENST00000308580.7
TMOD3
tropomodulin 3 (ubiquitous)
chr4_+_38665810 0.23 ENST00000261438.5
ENST00000514033.1
KLF3
Kruppel-like factor 3 (basic)
chr3_+_51575596 0.22 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr3_-_48885228 0.22 ENST00000454963.1
ENST00000296446.8
ENST00000419216.1
ENST00000265563.8
PRKAR2A
protein kinase, cAMP-dependent, regulatory, type II, alpha
chr11_-_77532050 0.22 ENST00000308488.6
RSF1
remodeling and spacing factor 1
chr11_-_57283159 0.21 ENST00000533263.1
ENST00000278426.3
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr16_+_70557685 0.19 ENST00000302516.5
ENST00000566095.2
ENST00000577085.1
ENST00000567654.1
SF3B3
splicing factor 3b, subunit 3, 130kDa
chr2_-_157189180 0.19 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_+_131862900 0.19 ENST00000438882.2
ENST00000538982.1
ENST00000404460.1
PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr21_+_38071430 0.18 ENST00000290399.6
SIM2
single-minded family bHLH transcription factor 2
chr18_+_56338618 0.17 ENST00000348428.3
MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr17_+_28804380 0.16 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
GOSR1
golgi SNAP receptor complex member 1
chr17_-_56084578 0.16 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
SRSF1
serine/arginine-rich splicing factor 1
chr13_-_21476900 0.15 ENST00000400602.2
ENST00000255305.6
XPO4
exportin 4
chr1_-_78225482 0.15 ENST00000524778.1
ENST00000370794.3
ENST00000370793.1
ENST00000370792.3
USP33
ubiquitin specific peptidase 33
chr2_+_192542850 0.15 ENST00000410026.2
NABP1
nucleic acid binding protein 1
chr7_+_139044621 0.15 ENST00000354926.4
C7orf55-LUC7L2
C7orf55-LUC7L2 readthrough
chrX_-_3631635 0.14 ENST00000262848.5
PRKX
protein kinase, X-linked
chr1_-_155211017 0.14 ENST00000536770.1
ENST00000368373.3
GBA
glucosidase, beta, acid
chr7_-_151217001 0.14 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr7_+_94285637 0.13 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chrX_-_74376108 0.13 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr4_+_139936905 0.12 ENST00000280614.2
CCRN4L
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr4_-_149365827 0.12 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr3_+_101292939 0.12 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
PCNP
PEST proteolytic signal containing nuclear protein
chrX_+_69664706 0.12 ENST00000194900.4
ENST00000374360.3
DLG3
discs, large homolog 3 (Drosophila)
chr13_+_114238997 0.11 ENST00000538138.1
ENST00000375370.5
TFDP1
transcription factor Dp-1
chr1_+_161284047 0.11 ENST00000367975.2
ENST00000342751.4
ENST00000432287.2
ENST00000392169.2
ENST00000513009.1
SDHC
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
chr5_-_142783175 0.11 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr15_+_41523335 0.11 ENST00000334660.5
CHP1
calcineurin-like EF-hand protein 1
chr2_-_240322643 0.10 ENST00000345617.3
HDAC4
histone deacetylase 4
chr1_+_64239657 0.10 ENST00000371080.1
ENST00000371079.1
ROR1
receptor tyrosine kinase-like orphan receptor 1
chr16_-_79634595 0.10 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr1_+_78470530 0.10 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chrX_+_73641286 0.10 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr14_-_21905395 0.09 ENST00000430710.3
ENST00000553283.1
CHD8
chromodomain helicase DNA binding protein 8
chrX_-_129244655 0.09 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chr1_-_35658736 0.09 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr8_-_38239732 0.08 ENST00000534155.1
ENST00000433384.2
ENST00000317025.8
ENST00000316985.3
WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr8_+_28351707 0.08 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3
frizzled family receptor 3
chr1_-_39339777 0.08 ENST00000397572.2
MYCBP
MYC binding protein
chr14_-_99737565 0.08 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr1_+_203274639 0.07 ENST00000290551.4
BTG2
BTG family, member 2
chr9_-_127905736 0.07 ENST00000336505.6
ENST00000373549.4
SCAI
suppressor of cancer cell invasion
chr1_+_145611010 0.07 ENST00000369291.5
RNF115
ring finger protein 115
chr2_+_155554797 0.06 ENST00000295101.2
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr5_-_168006591 0.06 ENST00000239231.6
PANK3
pantothenate kinase 3
chr10_+_101419187 0.06 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr12_-_67072714 0.06 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
GRIP1
glutamate receptor interacting protein 1
chr9_+_128024067 0.06 ENST00000461379.1
ENST00000394084.1
ENST00000394105.2
ENST00000470056.1
ENST00000394104.2
ENST00000265956.4
ENST00000394083.2
ENST00000495955.1
ENST00000467750.1
ENST00000297933.6
GAPVD1
GTPase activating protein and VPS9 domains 1
chr8_+_21946681 0.05 ENST00000289921.7
FAM160B2
family with sequence similarity 160, member B2
chr10_-_120101804 0.05 ENST00000369183.4
ENST00000369172.4
FAM204A
family with sequence similarity 204, member A
chr4_+_41992489 0.05 ENST00000264451.7
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr22_+_37309662 0.05 ENST00000403662.3
ENST00000262825.5
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr3_-_48632593 0.05 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr12_-_89918522 0.05 ENST00000529983.2
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr6_+_34857019 0.05 ENST00000360359.3
ENST00000535627.1
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr3_+_38495333 0.04 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr3_+_43328004 0.03 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK
SNF related kinase
chr16_-_67840442 0.03 ENST00000536251.1
ENST00000448631.2
ENST00000602677.1
ENST00000411657.2
ENST00000425512.2
ENST00000317506.3
RANBP10
RAN binding protein 10
chr7_+_4721885 0.02 ENST00000328914.4
FOXK1
forkhead box K1
chr20_+_60697480 0.02 ENST00000370915.1
ENST00000253001.4
ENST00000400318.2
ENST00000279068.6
ENST00000279069.7
LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chr2_+_134877740 0.02 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr18_+_43753974 0.01 ENST00000282059.6
ENST00000321319.6
C18orf25
chromosome 18 open reading frame 25

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUGCCC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1904933 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.3 0.9 GO:2000685 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.3 1.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.7 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 0.7 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.2 0.7 GO:0050923 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2 0.8 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.2 0.8 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.5 GO:0060061 Spemann organizer formation(GO:0060061)
0.2 0.8 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.9 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.8 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.4 GO:0019046 release from viral latency(GO:0019046)
0.1 0.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0009956 radial pattern formation(GO:0009956)
0.1 1.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.1 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 0.3 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:0048880 sensory system development(GO:0048880)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 1.6 GO:2000505 regulation of energy homeostasis(GO:2000505) regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.5 GO:0071372 response to light intensity(GO:0009642) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.8 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 1.0 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.6 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.9 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.3 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.2 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 1.6 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0099624 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) peptidyl-lysine deacetylation(GO:0034983) cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.6 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0031588 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0035501 MH1 domain binding(GO:0035501)
0.3 0.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 0.6 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 1.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.9 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.1 1.4 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.3 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0070402 NADPH binding(GO:0070402)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 ST G ALPHA I PATHWAY G alpha i Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction