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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ACAGUAU

Z-value: 1.01

Motif logo

logo of

miRNA associated with seed ACAGUAU

NamemiRBASE accession
hsa-miR-144-3p
MIMAT0000436

Activity profile of ACAGUAU motif

Sorted Z-values of ACAGUAU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_31479045 15.68 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr2_+_172778952 15.28 ENST00000392584.1
ENST00000264108.4
HAT1
histone acetyltransferase 1
chr20_-_32891151 13.51 ENST00000217426.2
AHCY
adenosylhomocysteinase
chr5_+_52776228 11.89 ENST00000256759.3
FST
follistatin
chr12_-_15942309 11.07 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr1_-_95392635 11.02 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr5_+_65440032 10.95 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr2_+_201676256 10.01 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
BZW1
basic leucine zipper and W2 domains 1
chr9_-_117880477 9.82 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
TNC
tenascin C
chr6_+_13615554 9.71 ENST00000451315.2
NOL7
nucleolar protein 7, 27kDa
chr2_-_227664474 8.76 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr3_-_195808952 8.73 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
TFRC
transferrin receptor
chr1_+_165796753 8.51 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr18_+_3451646 8.51 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr17_-_4269768 8.47 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr1_+_113161778 8.42 ENST00000263168.3
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr15_+_52311398 7.92 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr6_-_86352642 7.82 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr1_+_26798955 7.63 ENST00000361427.5
HMGN2
high mobility group nucleosomal binding domain 2
chr15_+_39873268 7.30 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chr3_+_30648066 6.93 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr15_-_49447835 6.89 ENST00000388901.5
ENST00000299259.6
COPS2
COP9 signalosome subunit 2
chr10_+_89622870 6.67 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr5_-_127873659 6.53 ENST00000262464.4
FBN2
fibrillin 2
chrX_-_108976521 6.51 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4
acyl-CoA synthetase long-chain family member 4
chr6_+_64281906 6.31 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_-_225840747 6.18 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr3_+_107241783 6.14 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr17_-_38574169 5.85 ENST00000423485.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr3_+_152017181 5.65 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chr1_-_78148324 5.53 ENST00000370801.3
ENST00000433749.1
ZZZ3
zinc finger, ZZ-type containing 3
chr2_-_178128528 5.50 ENST00000397063.4
ENST00000421929.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr4_-_139163491 5.46 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr10_+_5454505 5.41 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr10_-_79686284 5.40 ENST00000372391.2
ENST00000372388.2
DLG5
discs, large homolog 5 (Drosophila)
chrX_-_109561294 5.38 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr11_-_27494279 5.38 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr7_+_116139424 5.20 ENST00000222693.4
CAV2
caveolin 2
chr15_-_48470558 5.17 ENST00000324324.7
MYEF2
myelin expression factor 2
chr2_+_46926048 5.11 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr16_-_12009735 5.11 ENST00000439887.2
ENST00000434724.2
GSPT1
G1 to S phase transition 1
chr18_-_18691739 4.99 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr2_-_37899323 4.95 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr2_+_198365122 4.94 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chrX_-_41782249 4.93 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr1_+_955448 4.83 ENST00000379370.2
AGRN
agrin
chr7_-_27213893 4.75 ENST00000283921.4
HOXA10
homeobox A10
chr11_+_92085262 4.68 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr8_+_98881268 4.66 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr5_+_177631497 4.62 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr3_-_124774802 4.49 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr6_+_114178512 4.44 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr16_-_65155833 4.37 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chrX_-_99891796 4.32 ENST00000373020.4
TSPAN6
tetraspanin 6
chr10_+_95256356 4.28 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr5_-_38595498 4.26 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr16_-_47177874 4.11 ENST00000562435.1
NETO2
neuropilin (NRP) and tolloid (TLL)-like 2
chr1_+_93811438 4.05 ENST00000370272.4
ENST00000370267.1
DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr1_-_225615599 4.02 ENST00000421383.1
ENST00000272163.4
LBR
lamin B receptor
chr20_+_61427797 3.96 ENST00000370487.3
MRGBP
MRG/MORF4L binding protein
chr12_-_76425368 3.91 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr12_+_69004619 3.85 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B
RAP1B, member of RAS oncogene family
chr6_-_99797522 3.76 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr3_-_98620500 3.73 ENST00000326840.6
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr3_+_69812877 3.66 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr9_+_112810878 3.64 ENST00000434623.2
ENST00000374525.1
AKAP2
A kinase (PRKA) anchor protein 2
chr8_-_57123815 3.59 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr6_-_24721054 3.55 ENST00000378119.4
C6orf62
chromosome 6 open reading frame 62
chr12_+_104359576 3.54 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr6_+_160390102 3.53 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr15_-_48937982 3.44 ENST00000316623.5
FBN1
fibrillin 1
chr17_+_1733276 3.43 ENST00000254719.5
RPA1
replication protein A1, 70kDa
chr11_+_9685604 3.37 ENST00000447399.2
ENST00000318950.6
SWAP70
SWAP switching B-cell complex 70kDa subunit
chr20_+_19867150 3.33 ENST00000255006.6
RIN2
Ras and Rab interactor 2
chr14_+_23776024 3.31 ENST00000553781.1
ENST00000556100.1
ENST00000557236.1
ENST00000557579.1
BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 readthrough
BCL2-like 2
chr9_+_2621798 3.30 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr12_+_67663056 3.27 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr15_-_37390482 3.18 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr8_-_41166953 3.15 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr8_+_26149007 3.10 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr4_-_103748880 3.04 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr9_+_112542572 3.04 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr7_+_115850547 3.02 ENST00000358204.4
ENST00000455989.1
ENST00000537767.1
TES
testis derived transcript (3 LIM domains)
chr20_-_48729670 3.02 ENST00000371657.5
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr15_+_77223960 3.02 ENST00000394885.3
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr18_+_8717369 2.99 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA2
SOGA family member 2
chr2_-_65357225 2.98 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A
RAB1A, member RAS oncogene family
chr3_+_51575596 2.98 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr12_+_50135588 2.97 ENST00000423828.1
ENST00000550445.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr5_+_82767284 2.97 ENST00000265077.3
VCAN
versican
chr20_-_48770174 2.96 ENST00000341698.2
TMEM189-UBE2V1
TMEM189-UBE2V1 readthrough
chr1_+_110091189 2.94 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr14_-_21737610 2.94 ENST00000320084.7
ENST00000449098.1
ENST00000336053.6
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr15_-_56209306 2.94 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr5_+_86564739 2.94 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr21_-_43346790 2.91 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr12_+_4430371 2.89 ENST00000179259.4
C12orf5
chromosome 12 open reading frame 5
chr8_-_68255912 2.85 ENST00000262215.3
ENST00000519436.1
ARFGEF1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr3_-_176914238 2.81 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr1_+_153606513 2.77 ENST00000368694.3
CHTOP
chromatin target of PRMT1
chr16_-_10674528 2.73 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr3_+_130569429 2.72 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr1_+_116184566 2.71 ENST00000355485.2
ENST00000369510.4
VANGL1
VANGL planar cell polarity protein 1
chr8_+_125486939 2.68 ENST00000303545.3
RNF139
ring finger protein 139
chr8_-_23712312 2.63 ENST00000290271.2
STC1
stanniocalcin 1
chr15_+_96873921 2.60 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_-_100106419 2.59 ENST00000393445.3
ENST00000258428.3
REV1
REV1, polymerase (DNA directed)
chr6_-_82462425 2.58 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr13_+_26828275 2.58 ENST00000381527.3
CDK8
cyclin-dependent kinase 8
chrX_+_118708493 2.57 ENST00000371558.2
UBE2A
ubiquitin-conjugating enzyme E2A
chr8_-_67525473 2.57 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr10_+_60272814 2.52 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr13_-_50367057 2.49 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr2_+_85198216 2.48 ENST00000456682.1
ENST00000409785.4
KCMF1
potassium channel modulatory factor 1
chr3_+_9439400 2.47 ENST00000450326.1
ENST00000402198.1
ENST00000402466.1
SETD5
SET domain containing 5
chr10_-_13390270 2.46 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1
selenophosphate synthetase 1
chr7_+_116312411 2.44 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr11_-_95657231 2.41 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
MTMR2
myotubularin related protein 2
chr10_-_98346801 2.40 ENST00000371142.4
TM9SF3
transmembrane 9 superfamily member 3
chr13_-_48575443 2.39 ENST00000378654.3
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr7_-_148581251 2.38 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr3_+_99357319 2.36 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1
collagen, type VIII, alpha 1
chr10_-_43903217 2.35 ENST00000357065.4
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr1_+_39456895 2.35 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr10_-_126849068 2.34 ENST00000494626.2
ENST00000337195.5
CTBP2
C-terminal binding protein 2
chr12_+_13349650 2.34 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr3_-_81811312 2.32 ENST00000429644.2
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr3_+_105085734 2.31 ENST00000306107.5
ALCAM
activated leukocyte cell adhesion molecule
chr4_+_146402925 2.30 ENST00000302085.4
SMAD1
SMAD family member 1
chrX_-_131352152 2.29 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr3_+_141106643 2.27 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr1_-_103574024 2.27 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1
collagen, type XI, alpha 1
chr8_-_42065187 2.23 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT
plasminogen activator, tissue
chr16_+_69221028 2.23 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr12_+_27485823 2.22 ENST00000395901.2
ENST00000546179.1
ARNTL2
aryl hydrocarbon receptor nuclear translocator-like 2
chr16_-_87525651 2.22 ENST00000268616.4
ZCCHC14
zinc finger, CCHC domain containing 14
chr2_+_170590321 2.22 ENST00000392647.2
KLHL23
kelch-like family member 23
chr4_-_54930790 2.19 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr3_-_122233723 2.19 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr14_-_64010046 2.18 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr7_-_131241361 2.14 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL
podocalyxin-like
chr7_-_93633684 2.12 ENST00000222547.3
ENST00000425626.1
BET1
Bet1 golgi vesicular membrane trafficking protein
chrX_+_40944871 2.11 ENST00000378308.2
ENST00000324545.8
USP9X
ubiquitin specific peptidase 9, X-linked
chr10_+_63661053 2.08 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr2_+_204192942 2.08 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr2_+_198380289 2.08 ENST00000233892.4
ENST00000409916.1
MOB4
MOB family member 4, phocein
chr2_+_191273052 2.06 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
MFSD6
major facilitator superfamily domain containing 6
chr10_+_88516396 2.06 ENST00000372037.3
BMPR1A
bone morphogenetic protein receptor, type IA
chr10_+_17686124 2.05 ENST00000377524.3
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chrX_-_119694538 2.05 ENST00000371322.5
CUL4B
cullin 4B
chr1_+_87170247 2.02 ENST00000370558.4
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr9_-_125590818 2.00 ENST00000259467.4
PDCL
phosducin-like
chr6_-_79944336 1.99 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr13_-_107187462 1.97 ENST00000245323.4
EFNB2
ephrin-B2
chr21_-_27542972 1.97 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
APP
amyloid beta (A4) precursor protein
chr20_-_47804894 1.96 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
STAU1
staufen double-stranded RNA binding protein 1
chr15_-_83876758 1.96 ENST00000299633.4
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr18_+_57567180 1.96 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr11_+_9406169 1.95 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr1_-_245027833 1.94 ENST00000444376.2
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr16_-_88851618 1.92 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr18_-_9614515 1.87 ENST00000400556.3
ENST00000400555.3
PPP4R1
protein phosphatase 4, regulatory subunit 1
chr9_-_14314066 1.85 ENST00000397575.3
NFIB
nuclear factor I/B
chr14_+_23790655 1.84 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr7_+_55086794 1.82 ENST00000275493.2
ENST00000442591.1
EGFR
epidermal growth factor receptor
chr20_+_39657454 1.74 ENST00000361337.2
TOP1
topoisomerase (DNA) I
chr13_+_49550015 1.73 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr1_-_186649543 1.72 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr4_-_7873981 1.70 ENST00000360265.4
AFAP1
actin filament associated protein 1
chr3_+_150321068 1.69 ENST00000471696.1
ENST00000477889.1
ENST00000485923.1
SELT
Selenoprotein T
chr3_-_136471204 1.67 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1
stromal antigen 1
chr10_+_31608054 1.66 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr17_-_60142609 1.65 ENST00000397786.2
MED13
mediator complex subunit 13
chr10_+_115674530 1.65 ENST00000451472.1
AL162407.1
CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein
chr6_+_4890226 1.64 ENST00000343762.5
CDYL
chromodomain protein, Y-like
chr6_-_53409890 1.61 ENST00000229416.6
GCLC
glutamate-cysteine ligase, catalytic subunit
chr1_+_112162381 1.60 ENST00000433097.1
ENST00000369709.3
ENST00000436150.2
RAP1A
RAP1A, member of RAS oncogene family
chr1_+_2985760 1.58 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16
PR domain containing 16
chr1_+_198126093 1.55 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NEK7
NIMA-related kinase 7
chr2_-_216300784 1.55 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr10_+_93683519 1.54 ENST00000265990.6
BTAF1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
chr4_-_66536057 1.54 ENST00000273854.3
EPHA5
EPH receptor A5
chr2_-_40679186 1.53 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_+_208394616 1.53 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr5_+_138940742 1.49 ENST00000398733.3
ENST00000253815.2
ENST00000505007.1
UBE2D2
ubiquitin-conjugating enzyme E2D 2
chr1_-_217262969 1.47 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr5_-_142783175 1.47 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr9_-_16870704 1.46 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr12_-_57505121 1.42 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr9_+_118916082 1.40 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr1_+_193091080 1.40 ENST00000367435.3
CDC73
cell division cycle 73
chr12_+_121124599 1.40 ENST00000228506.3
MLEC
malectin
chr9_+_133454943 1.38 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr6_-_139695757 1.38 ENST00000367651.2
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr2_-_183903133 1.37 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr6_+_143929307 1.36 ENST00000427704.2
ENST00000305766.6
PHACTR2
phosphatase and actin regulator 2
chr20_-_48770244 1.35 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
TMEM189
transmembrane protein 189
chr6_-_111804393 1.35 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr12_-_54069856 1.33 ENST00000602871.1
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr2_-_225450013 1.33 ENST00000264414.4
CUL3
cullin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ACAGUAU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.5 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
2.8 11.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
2.4 7.3 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
2.4 7.2 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
2.3 6.9 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
2.1 8.5 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
2.1 2.1 GO:0048377 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
2.0 5.9 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.9 15.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
1.7 5.0 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
1.7 6.7 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.4 9.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.4 5.5 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
1.3 3.9 GO:0045210 FasL biosynthetic process(GO:0045210)
1.2 5.0 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.2 9.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
1.2 4.8 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
1.2 2.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
1.1 10.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
1.1 6.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.1 4.3 GO:0048861 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
1.1 3.2 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.0 4.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.9 2.8 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.9 6.2 GO:0090270 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.9 3.5 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.9 8.8 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.9 5.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.9 5.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.8 3.4 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.8 2.5 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.8 2.4 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.8 5.4 GO:0071896 negative regulation of hippo signaling(GO:0035331) protein localization to adherens junction(GO:0071896)
0.7 0.7 GO:0048369 lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.7 2.9 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.7 3.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.7 1.4 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.7 3.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.7 2.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.7 2.6 GO:0009956 radial pattern formation(GO:0009956)
0.6 8.8 GO:0040016 embryonic cleavage(GO:0040016)
0.6 1.8 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.6 1.8 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.6 2.4 GO:0046502 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.5 1.1 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.5 1.6 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.5 1.6 GO:0097327 response to antineoplastic agent(GO:0097327)
0.5 1.5 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.5 7.2 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.5 2.0 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.5 2.0 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.5 3.0 GO:0051025 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.5 5.4 GO:0051451 myoblast migration(GO:0051451)
0.5 11.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.5 3.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.5 2.8 GO:0060613 fat pad development(GO:0060613)
0.5 2.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.4 5.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 2.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.4 4.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.4 1.3 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 6.9 GO:0000338 protein deneddylation(GO:0000338)
0.4 2.0 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.4 1.2 GO:0090427 activation of meiosis(GO:0090427)
0.4 1.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.4 2.3 GO:0035989 tendon development(GO:0035989)
0.4 5.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.4 1.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.4 1.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.4 2.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 1.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.3 1.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.3 3.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 1.0 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.3 3.3 GO:0010265 SCF complex assembly(GO:0010265)
0.3 1.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3 0.6 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.3 0.9 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.3 2.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.3 2.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 0.9 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 4.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 2.0 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.3 2.8 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.3 0.8 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.3 7.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.3 8.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.3 5.1 GO:0032060 bleb assembly(GO:0032060)
0.3 1.8 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 5.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.3 0.8 GO:0090155 glucosylceramide biosynthetic process(GO:0006679) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.3 1.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 4.4 GO:0051764 actin crosslink formation(GO:0051764)
0.3 2.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3 2.0 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.3 1.5 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.3 0.8 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 11.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 1.2 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) maintenance of chromatin silencing(GO:0006344)
0.2 1.7 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 3.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.9 GO:0007538 primary sex determination(GO:0007538)
0.2 4.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 1.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 1.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 2.6 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.2 2.0 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.2 1.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 0.8 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 1.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 3.6 GO:0060736 prostate gland growth(GO:0060736)
0.2 1.1 GO:0007386 compartment pattern specification(GO:0007386)
0.2 1.3 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.2 0.5 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.2 0.7 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.2 2.7 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 10.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 1.2 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 3.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 1.5 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 4.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.7 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.7 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.9 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.9 GO:0009755 hormone-mediated signaling pathway(GO:0009755) steroid hormone mediated signaling pathway(GO:0043401)
0.1 1.4 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.1 5.2 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 1.9 GO:0097264 self proteolysis(GO:0097264)
0.1 0.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 2.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 7.2 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1 1.3 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1 3.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.3 GO:0061386 closure of optic fissure(GO:0061386)
0.1 6.2 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 1.0 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.9 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.6 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.7 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 3.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.9 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.5 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.4 GO:0035973 aggrephagy(GO:0035973)
0.1 0.3 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1 1.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.2 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 2.3 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 2.2 GO:0031639 plasminogen activation(GO:0031639) fibrinolysis(GO:0042730)
0.1 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 3.1 GO:1900449 regulation of neurotransmitter receptor activity(GO:0099601) regulation of glutamate receptor signaling pathway(GO:1900449)
0.1 1.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 3.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 2.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 5.6 GO:0045445 myoblast differentiation(GO:0045445)
0.1 1.1 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 1.5 GO:0003416 endochondral bone growth(GO:0003416)
0.1 2.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 2.8 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 2.9 GO:0046039 GTP metabolic process(GO:0046039)
0.1 3.6 GO:0031102 neuron projection regeneration(GO:0031102)
0.1 2.9 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.1 0.8 GO:0031274 regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.2 GO:1902938 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 0.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 2.1 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.9 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 1.6 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 0.2 GO:0010157 response to chlorate(GO:0010157)
0.1 0.9 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 1.2 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 3.2 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 1.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 2.9 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.7 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 2.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 1.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 1.3 GO:0007129 synapsis(GO:0007129)
0.0 1.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 2.6 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 2.4 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 3.6 GO:0051225 spindle assembly(GO:0051225)
0.0 3.6 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 2.6 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 2.3 GO:0075733 intracellular transport of virus(GO:0075733)
0.0 3.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.7 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 5.0 GO:0016573 histone acetylation(GO:0016573)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.9 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.9 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 3.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0051497 negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.0 2.4 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0 3.1 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 2.8 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 1.1 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 4.9 GO:0006457 protein folding(GO:0006457)
0.0 1.0 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
2.0 5.9 GO:0018444 translation release factor complex(GO:0018444)
1.8 8.8 GO:0005899 insulin receptor complex(GO:0005899)
1.2 8.4 GO:0071203 WASH complex(GO:0071203)
1.1 7.8 GO:0097452 GAIT complex(GO:0097452)
0.9 9.8 GO:0005614 interstitial matrix(GO:0005614)
0.8 6.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.7 11.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.7 9.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.7 2.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.7 8.8 GO:0005577 fibrinogen complex(GO:0005577)
0.6 1.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.6 14.7 GO:0016580 Sin3 complex(GO:0016580)
0.6 1.8 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.6 3.0 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.6 6.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.6 6.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.5 9.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.5 2.6 GO:0033503 HULC complex(GO:0033503)
0.5 2.8 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.5 10.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.4 3.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.4 5.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 5.6 GO:0043073 germ cell nucleus(GO:0043073)
0.3 7.9 GO:0032156 septin cytoskeleton(GO:0032156)
0.3 4.9 GO:0090543 Flemming body(GO:0090543)
0.3 1.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.3 4.9 GO:0005652 nuclear lamina(GO:0005652)
0.3 0.9 GO:0031213 RSF complex(GO:0031213)
0.3 5.0 GO:0032059 bleb(GO:0032059)
0.3 0.8 GO:0019034 viral replication complex(GO:0019034)
0.3 2.4 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.3 2.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 3.4 GO:0031209 SCAR complex(GO:0031209)
0.2 1.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 2.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 5.2 GO:0002080 acrosomal membrane(GO:0002080)
0.2 2.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 4.0 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 0.8 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 2.9 GO:0000346 transcription export complex(GO:0000346)
0.2 2.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 2.3 GO:0097470 ribbon synapse(GO:0097470)
0.2 2.4 GO:0045120 pronucleus(GO:0045120)
0.2 2.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 9.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.3 GO:0005827 polar microtubule(GO:0005827)
0.1 4.0 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.5 GO:0031417 NatC complex(GO:0031417)
0.1 1.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 6.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 4.8 GO:0005605 basal lamina(GO:0005605)
0.1 16.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 2.1 GO:0042588 zymogen granule(GO:0042588)
0.1 14.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.4 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 2.6 GO:0071564 npBAF complex(GO:0071564)
0.1 3.3 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 15.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 2.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 3.4 GO:0030027 lamellipodium(GO:0030027)
0.1 1.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 2.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.3 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.1 GO:0030426 growth cone(GO:0030426)
0.1 14.4 GO:0005681 spliceosomal complex(GO:0005681)
0.1 1.6 GO:0071141 SMAD protein complex(GO:0071141)
0.1 4.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.5 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 5.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 3.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 2.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 4.7 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.1 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.1 4.7 GO:0030175 filopodium(GO:0030175)
0.1 3.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 3.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 5.7 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 2.9 GO:0035579 specific granule membrane(GO:0035579)
0.0 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.6 GO:0097542 ciliary tip(GO:0097542)
0.0 7.1 GO:0005819 spindle(GO:0005819)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 1.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 9.5 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.4 GO:0043209 myelin sheath(GO:0043209)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.0 1.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.8 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 2.3 GO:0072562 blood microparticle(GO:0072562)
0.0 4.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.9 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
2.4 7.3 GO:0070052 collagen V binding(GO:0070052)
2.3 13.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.2 6.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
1.9 5.8 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.9 5.6 GO:0001069 regulatory region RNA binding(GO:0001069)
1.7 6.9 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
1.4 4.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
1.3 4.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
1.2 10.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
1.2 8.5 GO:0004849 uridine kinase activity(GO:0004849)
1.2 3.5 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
1.1 5.5 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
1.0 5.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.0 9.8 GO:0045545 syndecan binding(GO:0045545)
0.9 15.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.8 1.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.8 3.3 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
0.8 2.5 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.8 2.4 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.7 16.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.7 15.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.5 1.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.5 3.0 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.5 11.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.5 6.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 1.8 GO:0048408 epidermal growth factor binding(GO:0048408)
0.4 12.9 GO:0070410 co-SMAD binding(GO:0070410)
0.4 1.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.4 2.9 GO:0050815 phosphoserine binding(GO:0050815)
0.4 2.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.4 7.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 16.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 2.1 GO:0098821 BMP receptor activity(GO:0098821)
0.3 2.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 1.3 GO:0031208 POZ domain binding(GO:0031208)
0.3 3.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 1.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 3.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.3 6.6 GO:0004707 MAP kinase activity(GO:0004707)
0.3 1.5 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 1.7 GO:0003917 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.3 3.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 2.0 GO:0051425 PTB domain binding(GO:0051425)
0.3 1.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 2.4 GO:0070878 primary miRNA binding(GO:0070878)
0.3 0.8 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.3 5.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 2.5 GO:0050693 LBD domain binding(GO:0050693)
0.2 2.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 0.7 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 10.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 2.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 5.8 GO:0008143 poly(A) binding(GO:0008143)
0.2 1.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 1.5 GO:1990763 arrestin family protein binding(GO:1990763)
0.2 1.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 2.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 1.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 3.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 3.3 GO:0051400 BH domain binding(GO:0051400)
0.2 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.2 3.1 GO:0048156 tau protein binding(GO:0048156)
0.2 11.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 2.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.2 2.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.8 GO:0034056 estrogen response element binding(GO:0034056)
0.1 6.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.0 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 1.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.6 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.1 3.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.2 GO:0034452 dynactin binding(GO:0034452)
0.1 3.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 3.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 5.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 2.0 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 3.8 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 4.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 5.5 GO:0019003 GDP binding(GO:0019003)
0.1 3.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 3.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 1.0 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 2.6 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.9 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 3.0 GO:0050699 WW domain binding(GO:0050699)
0.1 1.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 25.5 GO:0045296 cadherin binding(GO:0045296)
0.1 0.9 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.6 GO:0031386 protein tag(GO:0031386)
0.1 4.6 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 3.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 2.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 2.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.8 GO:0070402 NADPH binding(GO:0070402)
0.0 5.3 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 4.6 GO:0004386 helicase activity(GO:0004386)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.4 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 2.0 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.4 GO:0032947 protein complex scaffold(GO:0032947)
0.0 2.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.3 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 6.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 2.3 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 2.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.6 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.2 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.4 29.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.3 10.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 4.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 8.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 12.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 14.3 PID BMP PATHWAY BMP receptor signaling
0.2 13.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 6.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 5.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 5.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 5.2 ST GA12 PATHWAY G alpha 12 Pathway
0.2 5.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 10.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 4.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 6.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 4.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.4 PID ATR PATHWAY ATR signaling pathway
0.1 2.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.0 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.2 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 2.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 2.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 4.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 4.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 11.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 4.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID EPO PATHWAY EPO signaling pathway
0.0 2.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.1 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 8.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 4.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 15.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 9.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 13.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 6.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 6.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 3.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 8.7 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.3 6.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2 3.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 8.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 7.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 3.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 18.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 2.9 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 4.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 7.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 5.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 6.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 4.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.8 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 2.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 1.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 5.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.9 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 5.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 7.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 3.5 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 3.9 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.3 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 1.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2