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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ACAUUCA

Z-value: 1.06

Motif logo

logo of

miRNA associated with seed ACAUUCA

NamemiRBASE accession
hsa-miR-181a-5p
MIMAT0000256
hsa-miR-181b-5p
MIMAT0000257
hsa-miR-181c-5p
MIMAT0000258
hsa-miR-181d-5p
MIMAT0002821
hsa-miR-4262
MIMAT0016894

Activity profile of ACAUUCA motif

Sorted Z-values of ACAUUCA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_10199468 12.52 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr4_+_158141843 12.45 ENST00000509417.1
ENST00000296526.7
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr14_+_90863327 10.52 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr8_+_26435359 9.89 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr5_-_108745689 9.10 ENST00000361189.2
PJA2
praja ring finger 2, E3 ubiquitin protein ligase
chr5_+_71403061 8.17 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr6_-_99797522 7.61 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr20_+_11871371 6.99 ENST00000254977.3
BTBD3
BTB (POZ) domain containing 3
chr1_+_50574585 6.98 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr15_-_51914996 6.88 ENST00000251076.5
DMXL2
Dmx-like 2
chr17_-_9929581 6.83 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr3_+_158991025 6.81 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr20_-_4804244 6.72 ENST00000379400.3
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chrX_+_135067576 6.69 ENST00000370701.1
ENST00000370698.3
ENST00000370695.4
SLC9A6
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
chr22_-_39239987 6.69 ENST00000333039.2
NPTXR
neuronal pentraxin receptor
chr7_+_153584166 6.68 ENST00000404039.1
DPP6
dipeptidyl-peptidase 6
chr4_+_154125565 6.59 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr22_-_39548627 6.48 ENST00000216133.5
CBX7
chromobox homolog 7
chr15_+_80696666 6.46 ENST00000303329.4
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr20_+_43514315 6.21 ENST00000353703.4
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr16_+_11762270 6.18 ENST00000329565.5
SNN
stannin
chr12_-_16761007 6.15 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr20_+_44657845 6.13 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr17_+_43971643 6.03 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
MAPT
microtubule-associated protein tau
chr15_+_66679155 5.88 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr3_+_186501336 5.80 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
EIF4A2
eukaryotic translation initiation factor 4A2
chr7_-_111846435 5.77 ENST00000437633.1
ENST00000428084.1
DOCK4
dedicator of cytokinesis 4
chr12_-_76953284 5.76 ENST00000547544.1
ENST00000393249.2
OSBPL8
oxysterol binding protein-like 8
chr13_-_77900814 5.68 ENST00000544440.2
MYCBP2
MYC binding protein 2, E3 ubiquitin protein ligase
chr5_+_140248518 5.60 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr5_+_140306478 5.54 ENST00000253807.2
PCDHAC1
protocadherin alpha subfamily C, 1
chr10_-_75634260 5.49 ENST00000372765.1
ENST00000351293.3
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr6_+_139456226 5.47 ENST00000367658.2
HECA
headcase homolog (Drosophila)
chr15_-_73925651 5.47 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN
neuroplastin
chr5_+_145826867 5.44 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr6_-_99873145 5.44 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr3_+_159557637 5.40 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr12_+_121837844 5.38 ENST00000361234.5
RNF34
ring finger protein 34, E3 ubiquitin protein ligase
chr12_-_22697343 5.32 ENST00000446597.1
ENST00000536386.1
ENST00000396028.2
ENST00000545552.1
ENST00000544930.1
ENST00000333957.4
C2CD5
C2 calcium-dependent domain containing 5
chrX_+_153665248 5.30 ENST00000447750.2
GDI1
GDP dissociation inhibitor 1
chr5_+_140254884 5.29 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr18_+_32558208 5.26 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr5_-_137368708 5.20 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr3_-_195163803 5.20 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr5_+_140220769 5.11 ENST00000531613.1
ENST00000378123.3
PCDHA8
protocadherin alpha 8
chr6_+_44238203 5.08 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr5_+_140213815 5.02 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr12_-_90049828 4.84 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr5_+_140345820 4.80 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr1_+_90286562 4.73 ENST00000525774.1
ENST00000337338.5
LRRC8D
leucine rich repeat containing 8 family, member D
chr5_+_140227048 4.72 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr10_-_15413035 4.58 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr10_+_1095416 4.54 ENST00000358220.1
WDR37
WD repeat domain 37
chr6_-_110500905 4.51 ENST00000392587.2
WASF1
WAS protein family, member 1
chr12_+_32112340 4.45 ENST00000540924.1
ENST00000312561.4
KIAA1551
KIAA1551
chr2_-_86790593 4.37 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr1_-_179846928 4.35 ENST00000367612.3
ENST00000609928.1
TOR1AIP2
torsin A interacting protein 2
chr8_+_21915368 4.32 ENST00000265800.5
ENST00000517418.1
DMTN
dematin actin binding protein
chr14_+_57735614 4.29 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr5_+_109025067 4.21 ENST00000261483.4
MAN2A1
mannosidase, alpha, class 2A, member 1
chr3_-_33481835 4.20 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr2_-_122407097 4.19 ENST00000409078.3
CLASP1
cytoplasmic linker associated protein 1
chr8_-_18871159 4.19 ENST00000327040.8
ENST00000440756.2
PSD3
pleckstrin and Sec7 domain containing 3
chr10_+_112679301 4.17 ENST00000265277.5
ENST00000369452.4
SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr6_+_69345166 4.07 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr5_+_161274685 4.02 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr10_+_99344104 4.00 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr12_-_46766577 3.96 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr8_+_11141925 3.94 ENST00000221086.3
MTMR9
myotubularin related protein 9
chr5_-_132073210 3.94 ENST00000378735.1
ENST00000378746.4
KIF3A
kinesin family member 3A
chr16_+_81069433 3.92 ENST00000299575.4
ATMIN
ATM interactor
chr13_-_79979919 3.75 ENST00000267229.7
RBM26
RNA binding motif protein 26
chr6_-_136610911 3.75 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCLAF1
BCL2-associated transcription factor 1
chr3_+_20081515 3.70 ENST00000263754.4
KAT2B
K(lysine) acetyltransferase 2B
chr6_-_16761678 3.69 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr10_+_129705299 3.67 ENST00000254667.3
PTPRE
protein tyrosine phosphatase, receptor type, E
chr2_-_50574856 3.64 ENST00000342183.5
NRXN1
neurexin 1
chr12_+_65563329 3.61 ENST00000308330.2
LEMD3
LEM domain containing 3
chr3_+_152017181 3.58 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1
muscleblind-like splicing regulator 1
chr4_+_47033345 3.58 ENST00000295454.3
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr10_-_27149792 3.51 ENST00000376140.3
ENST00000376170.4
ABI1
abl-interactor 1
chr14_-_64010046 3.46 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr2_-_152684977 3.40 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr10_+_70480963 3.37 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1
cell division cycle and apoptosis regulator 1
chr5_+_140165876 3.37 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr10_+_180987 3.35 ENST00000381591.1
ZMYND11
zinc finger, MYND-type containing 11
chr16_+_56225248 3.27 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr4_-_69215699 3.24 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr1_+_11072696 3.21 ENST00000240185.3
ENST00000476201.1
TARDBP
TAR DNA binding protein
chr1_+_24286287 3.20 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr2_-_38978492 3.18 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
SRSF7
serine/arginine-rich splicing factor 7
chr14_-_21493884 3.17 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2
NDRG family member 2
chr4_-_141677267 3.15 ENST00000442267.2
TBC1D9
TBC1 domain family, member 9 (with GRAM domain)
chr16_+_58497567 3.11 ENST00000258187.5
NDRG4
NDRG family member 4
chr1_-_205719295 3.06 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr11_+_108093839 3.06 ENST00000452508.2
ATM
ataxia telangiectasia mutated
chr12_-_118498958 3.00 ENST00000315436.3
WSB2
WD repeat and SOCS box containing 2
chr6_-_152958521 2.92 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1
spectrin repeat containing, nuclear envelope 1
chr11_+_47291193 2.91 ENST00000428807.1
ENST00000402799.1
ENST00000406482.1
ENST00000349238.3
ENST00000311027.5
ENST00000407859.3
ENST00000395344.3
ENST00000444117.1
MADD
MAP-kinase activating death domain
chr8_-_9008206 2.89 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr1_-_31538517 2.88 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
PUM1
pumilio RNA-binding family member 1
chr3_+_101292939 2.88 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
PCNP
PEST proteolytic signal containing nuclear protein
chrX_+_70752917 2.83 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr20_+_30865429 2.82 ENST00000375712.3
KIF3B
kinesin family member 3B
chr1_+_32930647 2.80 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chr2_+_120517174 2.75 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr6_+_36853607 2.74 ENST00000480824.2
ENST00000355190.3
ENST00000373685.1
C6orf89
chromosome 6 open reading frame 89
chr4_-_42659102 2.74 ENST00000264449.10
ENST00000510289.1
ENST00000381668.5
ATP8A1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr13_-_110438914 2.66 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr18_-_5544241 2.65 ENST00000341928.2
ENST00000540638.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr11_-_116968987 2.62 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr9_-_91793675 2.61 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr7_+_5085452 2.60 ENST00000353796.3
ENST00000396912.1
ENST00000396904.2
RBAK
RBAK-RBAKDN
RB-associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr14_+_55738021 2.59 ENST00000313833.4
FBXO34
F-box protein 34
chr16_+_53088885 2.56 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr22_-_44708731 2.54 ENST00000381176.4
KIAA1644
KIAA1644
chr17_+_45727204 2.50 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr1_-_78148324 2.47 ENST00000370801.3
ENST00000433749.1
ZZZ3
zinc finger, ZZ-type containing 3
chr2_-_16847084 2.46 ENST00000406434.1
ENST00000381323.3
FAM49A
family with sequence similarity 49, member A
chr12_-_8088871 2.42 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr3_+_45730733 2.41 ENST00000418611.1
ENST00000389061.5
SACM1L
SAC1 suppressor of actin mutations 1-like (yeast)
chr7_-_25019760 2.40 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3
oxysterol binding protein-like 3
chr16_-_66785699 2.38 ENST00000258198.2
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr6_-_18265050 2.35 ENST00000397239.3
DEK
DEK oncogene
chr12_+_62654119 2.34 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr4_+_88896819 2.34 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr15_+_68346501 2.33 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr5_+_65018017 2.33 ENST00000380985.5
ENST00000502464.1
NLN
neurolysin (metallopeptidase M3 family)
chr12_-_65515334 2.31 ENST00000286574.4
WIF1
WNT inhibitory factor 1
chr4_-_100867864 2.31 ENST00000442697.2
DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr7_-_121036337 2.30 ENST00000426156.1
ENST00000359943.3
ENST00000412653.1
FAM3C
family with sequence similarity 3, member C
chr2_+_74881355 2.30 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr5_+_140186647 2.28 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr1_+_198126093 2.27 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NEK7
NIMA-related kinase 7
chr8_-_101965146 2.27 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr5_+_10353780 2.26 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
MARCH6
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr16_+_50775948 2.24 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr12_-_49351303 2.23 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr6_-_79787902 2.22 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chrX_+_146993449 2.21 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
FMR1
fragile X mental retardation 1
chr1_-_85156216 2.20 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr2_-_43453734 2.18 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr7_+_65338230 2.16 ENST00000360768.3
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr6_-_154831779 2.15 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr19_+_30863271 2.11 ENST00000355537.3
ZNF536
zinc finger protein 536
chr17_+_65821780 2.09 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF
bromodomain PHD finger transcription factor
chr5_+_140261703 2.09 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chrY_+_15016725 2.08 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr3_-_133380731 2.06 ENST00000260810.5
TOPBP1
topoisomerase (DNA) II binding protein 1
chr17_-_62502639 2.06 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr13_-_36705425 2.03 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
DCLK1
doublecortin-like kinase 1
chr5_-_95768973 2.03 ENST00000311106.3
PCSK1
proprotein convertase subtilisin/kexin type 1
chr12_-_498620 2.01 ENST00000399788.2
ENST00000382815.4
KDM5A
lysine (K)-specific demethylase 5A
chr6_+_87865262 1.96 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr9_-_80646374 1.96 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr7_-_105029329 1.95 ENST00000393651.3
ENST00000460391.1
SRPK2
SRSF protein kinase 2
chr22_-_22221900 1.95 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1
chr15_+_43803143 1.94 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chr5_+_34929677 1.90 ENST00000342382.4
ENST00000382021.2
ENST00000303525.7
DNAJC21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr3_+_23986748 1.88 ENST00000312521.4
NR1D2
nuclear receptor subfamily 1, group D, member 2
chrX_+_46306624 1.88 ENST00000360017.5
KRBOX4
KRAB box domain containing 4
chr2_-_225811747 1.86 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr2_-_160472952 1.86 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr9_+_103204553 1.85 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr13_-_31038370 1.84 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr1_+_40627038 1.83 ENST00000372771.4
RLF
rearranged L-myc fusion
chr5_+_133861790 1.83 ENST00000395003.1
PHF15
jade family PHD finger 2
chr17_+_45608430 1.82 ENST00000322157.4
NPEPPS
aminopeptidase puromycin sensitive
chr10_-_98346801 1.81 ENST00000371142.4
TM9SF3
transmembrane 9 superfamily member 3
chr15_-_49447835 1.75 ENST00000388901.5
ENST00000299259.6
COPS2
COP9 signalosome subunit 2
chr5_-_1524015 1.73 ENST00000283415.3
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr7_+_12250886 1.72 ENST00000444443.1
ENST00000396667.3
TMEM106B
transmembrane protein 106B
chrX_+_40944871 1.71 ENST00000378308.2
ENST00000324545.8
USP9X
ubiquitin specific peptidase 9, X-linked
chr14_+_74111578 1.69 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1
dynein, axonemal, light chain 1
chr2_-_202316260 1.65 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr1_+_101702417 1.64 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr1_-_84464780 1.64 ENST00000260505.8
TTLL7
tubulin tyrosine ligase-like family, member 7
chr10_-_15210666 1.63 ENST00000378165.4
NMT2
N-myristoyltransferase 2
chr3_+_32147997 1.62 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr1_+_97187318 1.61 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr4_-_17513702 1.61 ENST00000428702.2
ENST00000508623.1
ENST00000513615.1
QDPR
quinoid dihydropteridine reductase
chr6_-_90062543 1.60 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr12_+_70636765 1.59 ENST00000552231.1
ENST00000229195.3
ENST00000547780.1
ENST00000418359.3
CNOT2
CCR4-NOT transcription complex, subunit 2
chr9_+_91933407 1.58 ENST00000375807.3
ENST00000339901.4
SECISBP2
SECIS binding protein 2
chr5_+_102455853 1.57 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr14_+_75745477 1.57 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr1_-_78225482 1.55 ENST00000524778.1
ENST00000370794.3
ENST00000370793.1
ENST00000370792.3
USP33
ubiquitin specific peptidase 33
chr20_+_37101455 1.55 ENST00000262879.6
ENST00000397042.3
ENST00000397038.1
ENST00000537204.1
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
chr8_-_67525473 1.53 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr5_-_171615315 1.51 ENST00000176763.5
STK10
serine/threonine kinase 10
chr6_+_138483058 1.48 ENST00000251691.4
KIAA1244
KIAA1244
chr10_-_3827417 1.48 ENST00000497571.1
ENST00000542957.1
KLF6
Kruppel-like factor 6
chr12_-_124457371 1.48 ENST00000238156.3
ENST00000545037.1
CCDC92
coiled-coil domain containing 92
chr5_-_111093406 1.46 ENST00000379671.3
NREP
neuronal regeneration related protein
chr3_-_197476560 1.46 ENST00000273582.5
KIAA0226
KIAA0226
chr3_-_142166904 1.45 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr11_-_85780086 1.44 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr10_-_735553 1.44 ENST00000280886.6
ENST00000423550.1
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr17_+_2496971 1.41 ENST00000397195.5
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr11_+_107879459 1.41 ENST00000393094.2
CUL5
cullin 5

Network of associatons between targets according to the STRING database.

First level regulatory network of ACAUUCA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.8 5.5 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.8 5.4 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
1.5 6.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.3 7.8 GO:0090170 regulation of Golgi inheritance(GO:0090170)
1.3 3.8 GO:0002276 basophil activation involved in immune response(GO:0002276)
1.2 3.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
1.2 6.0 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
1.2 5.8 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
1.0 8.2 GO:0032482 Rab protein signal transduction(GO:0032482)
1.0 6.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.0 3.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
1.0 4.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.9 2.8 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.9 3.6 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.8 5.8 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.8 2.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.8 7.9 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.8 2.3 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.8 3.1 GO:0019046 release from viral latency(GO:0019046)
0.7 2.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.7 4.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.7 2.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.7 1.4 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.7 2.7 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.7 6.8 GO:0072386 plus-end-directed organelle transport along microtubule(GO:0072386)
0.7 5.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.7 4.0 GO:0032328 alanine transport(GO:0032328)
0.7 3.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.6 2.5 GO:0031291 Ran protein signal transduction(GO:0031291)
0.6 4.8 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.6 2.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.6 1.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.6 2.9 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.6 4.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.6 6.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.6 1.7 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.5 4.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.5 1.6 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.5 1.6 GO:0018201 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.5 1.6 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.5 4.2 GO:0006013 mannose metabolic process(GO:0006013)
0.5 3.9 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.5 1.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.5 2.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.5 3.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.5 8.2 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.5 1.4 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.5 5.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.4 2.7 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.4 2.2 GO:2000301 regulation of intracellular transport of viral material(GO:1901252) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4 4.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 1.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.4 2.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 1.6 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072) negative regulation of protein kinase C signaling(GO:0090038)
0.4 2.0 GO:0035063 nuclear speck organization(GO:0035063)
0.4 4.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.4 7.6 GO:0071420 cellular response to histamine(GO:0071420)
0.4 2.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.4 1.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.4 0.8 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.4 1.9 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.4 2.9 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.4 1.4 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.4 0.7 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.3 1.0 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.3 3.4 GO:0036010 protein localization to endosome(GO:0036010)
0.3 1.0 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 1.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.3 3.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 2.2 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.3 1.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.3 1.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.3 2.9 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.3 5.5 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.3 1.2 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.3 1.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.3 0.8 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.3 1.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.3 0.8 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.3 1.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 0.3 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.3 2.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.3 0.8 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.3 11.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 12.7 GO:0035329 hippo signaling(GO:0035329)
0.3 0.8 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.2 2.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 3.1 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.2 38.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 0.7 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.2 1.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.9 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 4.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 0.9 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 2.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 2.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 2.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 10.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 1.0 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 1.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 0.6 GO:0061010 gall bladder development(GO:0061010)
0.2 3.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2 0.6 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 1.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 0.4 GO:1990036 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.2 4.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 0.7 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.2 1.8 GO:0015074 DNA integration(GO:0015074)
0.2 3.5 GO:0035855 megakaryocyte development(GO:0035855)
0.2 1.6 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 0.7 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.2 0.5 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.2 0.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 0.2 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2 1.0 GO:0071233 cellular response to leucine(GO:0071233)
0.2 4.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 2.3 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.9 GO:0015853 adenine transport(GO:0015853)
0.1 1.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 1.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 4.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 2.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.1 0.7 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 2.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.8 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.5 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 2.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.8 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.5 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 1.8 GO:0000338 protein deneddylation(GO:0000338)
0.1 3.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 2.4 GO:0051642 centrosome localization(GO:0051642)
0.1 1.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 13.1 GO:0048675 axon extension(GO:0048675)
0.1 0.1 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.1 1.9 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 1.4 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.9 GO:0051597 response to methylmercury(GO:0051597)
0.1 4.2 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 0.5 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 2.8 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1 0.3 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 1.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 1.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.9 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 6.7 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 1.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 2.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 2.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.1 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.9 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.7 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.8 GO:0009414 response to water deprivation(GO:0009414)
0.1 1.1 GO:0045116 protein neddylation(GO:0045116)
0.1 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 3.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.3 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.1 0.3 GO:0021610 facial nerve development(GO:0021561) facial nerve morphogenesis(GO:0021610)
0.1 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 1.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.7 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.7 GO:0061157 mRNA destabilization(GO:0061157)
0.1 1.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.3 GO:0030578 PML body organization(GO:0030578)
0.1 2.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.6 GO:0070977 bone maturation(GO:0070977)
0.1 1.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.0 3.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 6.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 4.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.5 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.3 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 1.0 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.8 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.5 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.7 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 2.4 GO:0045445 myoblast differentiation(GO:0045445)
0.0 3.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0032506 cytokinetic process(GO:0032506)
0.0 1.3 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.5 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.3 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 4.6 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.7 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.6 GO:0003016 respiratory system process(GO:0003016)
0.0 0.6 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 1.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 1.0 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.0 GO:2000843 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 2.6 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.4 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.0 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.6 GO:0060966 regulation of posttranscriptional gene silencing(GO:0060147) regulation of gene silencing by miRNA(GO:0060964) regulation of gene silencing by RNA(GO:0060966)
0.0 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0015866 ADP transport(GO:0015866)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.6 GO:0019985 translesion synthesis(GO:0019985)
0.0 2.5 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 1.0 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 1.0 GO:1904667 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 2.7 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
2.5 12.4 GO:0098843 postsynaptic endocytic zone(GO:0098843)
2.3 6.9 GO:0043291 RAVE complex(GO:0043291)
1.7 6.8 GO:0016939 kinesin II complex(GO:0016939)
1.3 6.7 GO:0044308 axonal spine(GO:0044308)
1.2 6.0 GO:0045298 tubulin complex(GO:0045298)
1.1 4.2 GO:0005797 Golgi medial cisterna(GO:0005797)
1.0 4.2 GO:0035838 growing cell tip(GO:0035838)
0.8 4.5 GO:0070545 PeBoW complex(GO:0070545)
0.7 3.7 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.7 2.2 GO:0034657 GID complex(GO:0034657)
0.7 2.2 GO:0019034 viral replication complex(GO:0019034)
0.7 4.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.6 3.2 GO:0035061 perichromatin fibrils(GO:0005726) interchromatin granule(GO:0035061)
0.6 8.0 GO:0031209 SCAR complex(GO:0031209)
0.5 9.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 5.5 GO:0060077 inhibitory synapse(GO:0060077)
0.4 3.7 GO:0000125 PCAF complex(GO:0000125)
0.4 1.2 GO:0000806 Y chromosome(GO:0000806)
0.3 4.5 GO:0000815 ESCRT III complex(GO:0000815)
0.3 2.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.3 1.6 GO:0030891 VCB complex(GO:0030891)
0.3 4.7 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.3 1.2 GO:0000798 nuclear cohesin complex(GO:0000798)
0.3 2.1 GO:0016589 NURF complex(GO:0016589)
0.3 0.9 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.3 1.4 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.3 1.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 4.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 2.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 5.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 4.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 6.1 GO:0035371 microtubule plus-end(GO:0035371)
0.2 1.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 2.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 1.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 2.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2 7.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 1.7 GO:0036157 outer dynein arm(GO:0036157)
0.2 1.0 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.2 1.6 GO:0035976 AP1 complex(GO:0035976)
0.2 1.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 1.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 2.4 GO:0032433 filopodium tip(GO:0032433)
0.2 1.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 5.8 GO:0032420 stereocilium(GO:0032420)
0.2 2.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 2.6 GO:0033270 paranode region of axon(GO:0033270)
0.2 1.1 GO:0031415 NatA complex(GO:0031415)
0.1 2.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.7 GO:1990752 microtubule end(GO:1990752)
0.1 6.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 2.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 10.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 2.2 GO:0012505 endomembrane system(GO:0012505)
0.1 2.0 GO:0071141 SMAD protein complex(GO:0071141)
0.1 2.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.2 GO:0097542 ciliary tip(GO:0097542)
0.1 3.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 3.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 0.6 GO:0070652 HAUS complex(GO:0070652)
0.1 3.3 GO:0043198 dendritic shaft(GO:0043198)
0.1 4.6 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 5.2 GO:0010008 endosome membrane(GO:0010008)
0.1 6.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 1.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 9.4 GO:0000922 spindle pole(GO:0000922)
0.1 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.3 GO:0030914 STAGA complex(GO:0030914)
0.1 3.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.1 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.1 1.3 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.0 2.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 4.3 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 11.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 4.0 GO:0005819 spindle(GO:0005819)
0.0 14.8 GO:0005815 microtubule organizing center(GO:0005815)
0.0 3.4 GO:0030496 midbody(GO:0030496)
0.0 3.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 3.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 3.3 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 4.6 GO:0034702 ion channel complex(GO:0034702)
0.0 3.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 10.0 GO:0005874 microtubule(GO:0005874)
0.0 1.3 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.4 GO:0031941 filamentous actin(GO:0031941)
0.0 2.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 12.4 GO:0016607 nuclear speck(GO:0016607)
0.0 5.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 4.3 GO:0042383 sarcolemma(GO:0042383)
0.0 0.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 5.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.1 GO:0036126 sperm flagellum(GO:0036126)
0.0 2.2 GO:0016604 nuclear body(GO:0016604)
0.0 0.3 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 2.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 1.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0009986 cell surface(GO:0009986)
0.0 0.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.3 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.5 6.0 GO:0099609 microtubule lateral binding(GO:0099609)
1.4 5.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.2 3.6 GO:0001069 regulatory region RNA binding(GO:0001069)
1.2 5.9 GO:0034046 poly(G) binding(GO:0034046)
1.0 4.2 GO:0043515 kinetochore binding(GO:0043515)
1.0 4.2 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
1.0 12.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.9 2.8 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.9 6.2 GO:0050815 phosphoserine binding(GO:0050815)
0.8 2.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.8 4.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.7 3.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.7 6.9 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.7 2.1 GO:0035500 MH2 domain binding(GO:0035500)
0.6 1.8 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.6 2.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.6 6.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 1.6 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.5 2.2 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.5 3.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.5 2.0 GO:0005057 receptor signaling protein activity(GO:0005057)
0.5 4.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.5 2.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.5 4.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.5 2.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.4 5.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 12.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 2.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.4 5.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.4 5.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.4 8.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.4 3.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.4 3.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.3 1.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.3 1.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.3 4.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.3 1.6 GO:0070404 NADH binding(GO:0070404)
0.3 4.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 1.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 1.8 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.3 1.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.3 0.9 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.3 6.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 5.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3 3.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 7.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 4.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.3 2.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 1.6 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.3 7.7 GO:0070064 proline-rich region binding(GO:0070064)
0.3 3.3 GO:0003712 transcription cofactor activity(GO:0003712)
0.2 1.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 5.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 0.5 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.2 0.7 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 6.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.4 GO:0017018 myosin phosphatase activity(GO:0017018)
0.2 2.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 8.1 GO:0017091 AU-rich element binding(GO:0017091)
0.2 0.9 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.2 5.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 1.0 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 5.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 1.0 GO:0070728 leucine binding(GO:0070728)
0.2 1.9 GO:0042731 PH domain binding(GO:0042731)
0.2 4.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.4 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.2 1.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.8 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.2 1.5 GO:0034452 dynactin binding(GO:0034452)
0.2 1.6 GO:0046625 sphingolipid binding(GO:0046625)
0.2 0.6 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 4.0 GO:0035064 methylated histone binding(GO:0035064)
0.2 2.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 0.6 GO:0036033 mediator complex binding(GO:0036033)
0.1 3.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.6 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.7 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 3.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 2.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 3.6 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 9.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 1.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.5 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 1.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 7.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 2.9 GO:0005521 lamin binding(GO:0005521)
0.1 1.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 6.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 3.9 GO:0030507 spectrin binding(GO:0030507)
0.1 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 4.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.7 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.5 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.1 1.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.8 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 2.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.1 6.8 GO:0002039 p53 binding(GO:0002039)
0.1 2.4 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 2.7 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 2.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 11.2 GO:0044325 ion channel binding(GO:0044325)
0.1 0.9 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 15.5 GO:0008017 microtubule binding(GO:0008017)
0.1 0.6 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 6.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.1 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 7.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 4.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.3 GO:0030276 clathrin binding(GO:0030276)
0.0 1.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 1.5 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 24.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 1.5 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 2.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 5.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 1.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 1.2 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 4.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 6.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 18.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 3.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 10.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 9.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 3.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 2.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 2.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 5.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 4.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 6.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 5.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 2.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.1 PID BARD1 PATHWAY BARD1 signaling events
0.1 4.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.6 PID TNF PATHWAY TNF receptor signaling pathway
0.1 2.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.0 PID EPO PATHWAY EPO signaling pathway
0.0 0.8 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.4 PID ATM PATHWAY ATM pathway
0.0 1.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 15.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.0 12.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.7 12.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.5 10.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.5 2.6 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.5 9.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.5 3.6 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.3 4.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 3.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 1.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.3 1.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.3 7.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 4.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 7.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 3.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 7.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 6.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 2.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.9 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 4.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.8 REACTOME KINESINS Genes involved in Kinesins
0.1 2.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 10.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 7.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 3.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 12.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 16.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 4.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis