averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr7_+_94023873 Show fit | 39.45 |
ENST00000297268.6
|
collagen, type I, alpha 2 |
|
chr2_+_189839046 Show fit | 31.77 |
ENST00000304636.3
ENST00000317840.5 |
collagen, type III, alpha 1 |
|
chr1_-_204380919 Show fit | 28.81 |
ENST00000367188.4
|
protein phosphatase 1, regulatory subunit 15B |
|
chr2_-_238323007 Show fit | 27.71 |
ENST00000295550.4
|
collagen, type VI, alpha 3 |
|
chr15_-_48937982 Show fit | 23.05 |
ENST00000316623.5
|
fibrillin 1 |
|
chr3_-_120170052 Show fit | 22.24 |
ENST00000295633.3
|
follistatin-like 1 |
|
chr1_-_35325400 Show fit | 20.52 |
ENST00000521580.2
|
small integral membrane protein 12 |
|
chr16_-_46865047 Show fit | 20.28 |
ENST00000394806.2
|
chromosome 16 open reading frame 87 |
|
chr16_+_55512742 Show fit | 19.67 |
ENST00000568715.1
ENST00000219070.4 |
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) |
|
chr1_+_151043070 Show fit | 18.81 |
ENST00000368918.3
ENST00000368917.1 |
GA binding protein transcription factor, beta subunit 2 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 46.7 | GO:0030199 | collagen fibril organization(GO:0030199) |
0.7 | 44.7 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.1 | 43.7 | GO:0043687 | post-translational protein modification(GO:0043687) |
2.8 | 39.5 | GO:0043589 | skin morphogenesis(GO:0043589) |
6.9 | 34.7 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
4.0 | 31.8 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
3.3 | 29.9 | GO:1903898 | negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
7.0 | 28.2 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
0.1 | 23.3 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
4.6 | 23.1 | GO:0035582 | sequestering of BMP in extracellular matrix(GO:0035582) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
10.3 | 92.5 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.3 | 82.0 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 53.4 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
4.2 | 41.8 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
0.2 | 41.1 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.5 | 37.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
12.1 | 36.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
2.2 | 33.3 | GO:0098644 | complex of collagen trimers(GO:0098644) |
0.2 | 31.1 | GO:0005923 | bicellular tight junction(GO:0005923) |
1.7 | 28.8 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
9.9 | 138.9 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.7 | 66.1 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 48.1 | GO:0005509 | calcium ion binding(GO:0005509) |
0.4 | 41.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.3 | 39.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 35.5 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
1.9 | 23.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
3.3 | 23.1 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
0.0 | 21.6 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.2 | 18.4 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.4 | 209.0 | NABA COLLAGENS | Genes encoding collagen proteins |
0.2 | 49.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.2 | 32.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.6 | 31.5 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
0.6 | 26.0 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
0.8 | 23.1 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.6 | 20.1 | PID S1P S1P1 PATHWAY | S1P1 pathway |
0.4 | 12.2 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
0.2 | 10.6 | PID FGF PATHWAY | FGF signaling pathway |
0.2 | 10.4 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.4 | 223.1 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
0.8 | 19.7 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.6 | 17.2 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.4 | 17.0 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.9 | 16.0 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.1 | 15.4 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.1 | 13.6 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.5 | 13.0 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.0 | 11.5 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
0.2 | 10.3 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |