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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AGCUUAU

Z-value: 0.88

Motif logo

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miRNA associated with seed AGCUUAU

NamemiRBASE accession
hsa-miR-21-5p
MIMAT0000076
hsa-miR-590-5p
MIMAT0003258

Activity profile of AGCUUAU motif

Sorted Z-values of AGCUUAU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_139876812 10.19 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chrX_-_18372792 9.34 ENST00000251900.4
SCML2
sex comb on midleg-like 2 (Drosophila)
chr22_+_33197683 8.91 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr7_-_44924939 7.48 ENST00000395699.2
PURB
purine-rich element binding protein B
chr4_+_124320665 6.65 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr3_-_18466787 6.60 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr10_+_112631547 6.34 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr17_+_17942594 6.25 ENST00000268719.4
GID4
GID complex subunit 4
chr7_+_102715315 6.22 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10
armadillo repeat containing 10
chr2_-_43453734 6.14 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr2_-_37193606 6.11 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr16_-_75498553 5.87 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
TMEM170A
RP11-77K12.1
transmembrane protein 170A
Uncharacterized protein
chr13_-_41706864 5.27 ENST00000379485.1
ENST00000499385.2
KBTBD6
kelch repeat and BTB (POZ) domain containing 6
chr5_-_160973649 5.10 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chrX_-_54384425 5.05 ENST00000375169.3
ENST00000354646.2
WNK3
WNK lysine deficient protein kinase 3
chr4_+_113152881 4.57 ENST00000274000.5
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr8_-_57123815 4.46 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr1_-_207224307 4.44 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr5_+_56111361 4.40 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr2_-_64371546 4.32 ENST00000358912.4
PELI1
pellino E3 ubiquitin protein ligase 1
chr16_-_4292071 4.24 ENST00000399609.3
SRL
sarcalumenin
chr7_+_138916231 4.11 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr9_+_36036430 4.01 ENST00000377966.3
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr13_+_73632897 3.87 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr1_-_72748417 3.72 ENST00000357731.5
NEGR1
neuronal growth regulator 1
chr3_-_24536253 3.71 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB
thyroid hormone receptor, beta
chr11_+_33278811 3.49 ENST00000303296.4
ENST00000379016.3
HIPK3
homeodomain interacting protein kinase 3
chr8_-_82024290 3.41 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr8_-_9008206 3.27 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr11_-_64646086 3.27 ENST00000320631.3
EHD1
EH-domain containing 1
chr1_+_203274639 3.18 ENST00000290551.4
BTG2
BTG family, member 2
chr10_+_72164135 3.17 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr8_+_98881268 3.16 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr17_+_59477233 3.09 ENST00000240328.3
TBX2
T-box 2
chr5_-_32313019 3.00 ENST00000280285.5
ENST00000264934.5
MTMR12
myotubularin related protein 12
chr16_+_12070567 2.92 ENST00000566228.1
SNX29
sorting nexin 29
chr2_-_201936302 2.88 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr1_+_33005020 2.70 ENST00000373510.4
ENST00000316459.4
ZBTB8A
zinc finger and BTB domain containing 8A
chr12_-_121342170 2.70 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr8_+_75736761 2.67 ENST00000260113.2
PI15
peptidase inhibitor 15
chr10_-_94003003 2.62 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr3_+_141205852 2.60 ENST00000286364.3
ENST00000452898.1
RASA2
RAS p21 protein activator 2
chr3_+_186648274 2.56 ENST00000169298.3
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr14_+_33408449 2.52 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3
neuronal PAS domain protein 3
chr4_+_48018781 2.51 ENST00000295461.5
NIPAL1
NIPA-like domain containing 1
chr4_+_38665810 2.43 ENST00000261438.5
ENST00000514033.1
KLF3
Kruppel-like factor 3 (basic)
chr20_-_10654639 2.32 ENST00000254958.5
JAG1
jagged 1
chr15_-_42840961 2.30 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57
leucine rich repeat containing 57
chr2_+_148602058 2.26 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A
activin A receptor, type IIA
chr3_+_30648066 2.26 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr2_-_218808771 2.18 ENST00000449814.1
ENST00000171887.4
TNS1
tensin 1
chr2_+_86947296 2.13 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr19_+_1286097 2.08 ENST00000215368.2
EFNA2
ephrin-A2
chr10_+_75757863 1.98 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL
vinculin
chr17_+_21187976 1.96 ENST00000342679.4
MAP2K3
mitogen-activated protein kinase kinase 3
chr7_-_91875358 1.91 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1
KRIT1, ankyrin repeat containing
chr10_+_76871454 1.89 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr11_-_130786400 1.87 ENST00000265909.4
SNX19
sorting nexin 19
chr18_+_67956135 1.85 ENST00000397942.3
SOCS6
suppressor of cytokine signaling 6
chr14_-_99737565 1.84 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr20_-_3996036 1.83 ENST00000336095.6
RNF24
ring finger protein 24
chr20_-_23030296 1.83 ENST00000377103.2
THBD
thrombomodulin
chr5_+_67511524 1.76 ENST00000521381.1
ENST00000521657.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr10_-_3827417 1.70 ENST00000497571.1
ENST00000542957.1
KLF6
Kruppel-like factor 6
chr2_+_70142189 1.70 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr12_+_69864129 1.69 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2
fibroblast growth factor receptor substrate 2
chr7_-_113559104 1.61 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr12_+_5019061 1.61 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr12_-_12419703 1.60 ENST00000543091.1
ENST00000261349.4
LRP6
low density lipoprotein receptor-related protein 6
chr15_-_38856836 1.53 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chrX_-_19140677 1.52 ENST00000357544.3
ENST00000379869.3
ENST00000360279.4
ENST00000379873.2
ENST00000379878.3
ENST00000354791.3
ENST00000379876.1
GPR64
G protein-coupled receptor 64
chr3_-_48229846 1.52 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr8_-_10588010 1.50 ENST00000304501.1
SOX7
SRY (sex determining region Y)-box 7
chr4_-_111544254 1.50 ENST00000306732.3
PITX2
paired-like homeodomain 2
chr5_-_54281491 1.49 ENST00000381405.4
ESM1
endothelial cell-specific molecule 1
chr8_+_56014949 1.44 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr12_-_117319236 1.41 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr11_-_1593150 1.40 ENST00000397374.3
DUSP8
dual specificity phosphatase 8
chr10_+_98741041 1.38 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr17_-_33416231 1.38 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr12_+_85673868 1.37 ENST00000316824.3
ALX1
ALX homeobox 1
chr2_-_71454185 1.35 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr15_+_59063478 1.33 ENST00000559228.1
ENST00000450403.2
FAM63B
family with sequence similarity 63, member B
chr15_-_55881135 1.31 ENST00000302000.6
PYGO1
pygopus family PHD finger 1
chr6_+_142468361 1.30 ENST00000367630.4
VTA1
vesicle (multivesicular body) trafficking 1
chr16_+_57392684 1.28 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr3_+_159706537 1.22 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr22_+_40573921 1.21 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr4_+_144257915 1.19 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr2_-_69870835 1.13 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr5_+_172483347 1.07 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF
CREB3 regulatory factor
chr18_-_60987220 1.07 ENST00000398117.1
BCL2
B-cell CLL/lymphoma 2
chr2_+_45878790 1.03 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr18_-_29522989 1.01 ENST00000582539.1
ENST00000283351.4
ENST00000582513.1
TRAPPC8
trafficking protein particle complex 8
chr3_+_29322803 1.01 ENST00000396583.3
ENST00000383767.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr6_-_82462425 1.00 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr22_+_39101728 0.99 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr12_+_65563329 0.97 ENST00000308330.2
LEMD3
LEM domain containing 3
chr11_+_32851487 0.88 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr1_+_64239657 0.88 ENST00000371080.1
ENST00000371079.1
ROR1
receptor tyrosine kinase-like orphan receptor 1
chr17_+_35766965 0.87 ENST00000394395.2
ENST00000589153.1
ENST00000586023.1
TADA2A
transcriptional adaptor 2A
chr4_-_140098339 0.87 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr1_+_154377669 0.83 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr16_-_4897266 0.82 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr3_+_98451275 0.79 ENST00000265261.6
ENST00000497008.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr2_+_20646824 0.79 ENST00000272233.4
RHOB
ras homolog family member B
chr5_+_170846640 0.79 ENST00000274625.5
FGF18
fibroblast growth factor 18
chr4_-_89744457 0.78 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr9_-_16870704 0.75 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr4_+_86396265 0.74 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr12_+_12764773 0.73 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr12_+_5541267 0.72 ENST00000423158.3
NTF3
neurotrophin 3
chr1_-_115053781 0.70 ENST00000358465.2
ENST00000369543.2
TRIM33
tripartite motif containing 33
chr7_+_11013491 0.68 ENST00000403050.3
ENST00000445996.2
PHF14
PHD finger protein 14
chr4_+_81951957 0.66 ENST00000282701.2
BMP3
bone morphogenetic protein 3
chr14_+_57046500 0.65 ENST00000261556.6
TMEM260
transmembrane protein 260
chr1_+_172628154 0.65 ENST00000340030.3
ENST00000367721.2
FASLG
Fas ligand (TNF superfamily, member 6)
chr8_-_41909496 0.63 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A
K(lysine) acetyltransferase 6A
chr17_+_58755184 0.60 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr16_+_69599861 0.60 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_+_120207787 0.59 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr10_-_35930219 0.59 ENST00000374694.1
FZD8
frizzled family receptor 8
chr17_+_46184911 0.59 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
SNX11
sorting nexin 11
chr9_-_123476719 0.59 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr1_+_2160134 0.58 ENST00000378536.4
SKI
v-ski avian sarcoma viral oncogene homolog
chr7_-_92463210 0.57 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr12_-_9913489 0.54 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr12_-_42538657 0.53 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr4_-_100867864 0.51 ENST00000442697.2
DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr15_-_102029873 0.51 ENST00000348070.1
ENST00000358417.3
ENST00000344273.2
PCSK6
proprotein convertase subtilisin/kexin type 6
chr7_-_81399438 0.51 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_-_115632035 0.51 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2
tetraspanin 2
chr12_-_40013553 0.49 ENST00000308666.3
ABCD2
ATP-binding cassette, sub-family D (ALD), member 2
chr2_+_70314579 0.49 ENST00000303577.5
PCBP1
poly(rC) binding protein 1
chr1_+_213123915 0.47 ENST00000366968.4
ENST00000490792.1
VASH2
vasohibin 2
chr13_-_110959478 0.43 ENST00000543140.1
ENST00000375820.4
COL4A1
collagen, type IV, alpha 1
chr8_+_87354945 0.42 ENST00000517970.1
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr11_-_44331679 0.40 ENST00000329255.3
ALX4
ALX homeobox 4
chr1_+_222791417 0.40 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
MIA3
melanoma inhibitory activity family, member 3
chr9_-_34589700 0.39 ENST00000351266.4
CNTFR
ciliary neurotrophic factor receptor
chr17_+_61627814 0.39 ENST00000310827.4
ENST00000431926.1
ENST00000415273.2
DCAF7
DDB1 and CUL4 associated factor 7
chr5_+_154238096 0.39 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
CNOT8
CCR4-NOT transcription complex, subunit 8
chr1_-_214724566 0.38 ENST00000366956.5
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr8_+_9413410 0.37 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr7_+_89975979 0.34 ENST00000257659.8
ENST00000222511.6
ENST00000417207.1
GTPBP10
GTP-binding protein 10 (putative)
chrX_+_46696372 0.31 ENST00000218340.3
RP2
retinitis pigmentosa 2 (X-linked recessive)
chr3_+_181429704 0.29 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr1_+_36273743 0.27 ENST00000373210.3
AGO4
argonaute RISC catalytic component 4
chr13_-_36920420 0.12 ENST00000438666.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr19_+_14492247 0.08 ENST00000357355.3
ENST00000592261.2
ENST00000242786.5
CD97
CD97 molecule
chr5_+_139493665 0.06 ENST00000331327.3
PURA
purine-rich element binding protein A
chr2_+_228678550 0.00 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCUUAU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 13.0 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
2.2 8.9 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.5 4.6 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
1.5 4.4 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
1.3 5.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
1.2 3.7 GO:0008050 female courtship behavior(GO:0008050)
1.1 4.3 GO:0008063 Toll signaling pathway(GO:0008063)
1.0 6.7 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.9 2.6 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.8 3.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.8 2.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.8 2.3 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.6 1.9 GO:1990502 dense core granule maturation(GO:1990502)
0.6 3.1 GO:0007521 muscle cell fate determination(GO:0007521)
0.6 1.7 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.5 1.6 GO:0090244 trachea cartilage morphogenesis(GO:0060535) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.5 4.0 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.5 1.5 GO:0060577 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.5 7.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5 1.8 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.4 3.9 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.4 2.3 GO:0042713 sperm ejaculation(GO:0042713)
0.4 5.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.4 1.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 1.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 2.5 GO:0015693 magnesium ion transport(GO:0015693)
0.3 4.4 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.3 0.8 GO:0002384 hepatic immune response(GO:0002384)
0.3 5.1 GO:0071420 cellular response to histamine(GO:0071420)
0.3 1.5 GO:0032252 secretory granule localization(GO:0032252)
0.3 1.0 GO:0030242 pexophagy(GO:0030242)
0.2 4.5 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.2 2.0 GO:0035897 proteolysis in other organism(GO:0035897)
0.2 1.0 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.2 1.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 3.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 1.6 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 0.7 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 0.6 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.2 1.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.2 2.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 3.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 4.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 1.8 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.2 0.8 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 1.2 GO:0002839 positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.6 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 1.8 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.1 0.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 2.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 2.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 1.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.5 GO:0032898 nerve growth factor processing(GO:0032455) neurotrophin production(GO:0032898)
0.1 1.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.5 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 4.4 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.2 GO:0035690 cellular response to drug(GO:0035690)
0.1 1.4 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 6.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 2.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.5 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.1 0.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 1.3 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 3.2 GO:0031102 neuron projection regeneration(GO:0031102)
0.1 3.0 GO:1901998 toxin transport(GO:1901998)
0.1 0.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 3.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.4 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 0.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.9 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 5.3 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 1.5 GO:0021772 olfactory bulb development(GO:0021772)
0.0 0.8 GO:0043586 tongue development(GO:0043586)
0.0 2.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.8 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 1.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.8 GO:0097503 sialylation(GO:0097503)
0.0 0.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.9 GO:0014002 astrocyte development(GO:0014002)
0.0 0.4 GO:0003360 brainstem development(GO:0003360)
0.0 2.7 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.5 GO:0001706 endoderm formation(GO:0001706)
0.0 7.1 GO:0045637 regulation of myeloid cell differentiation(GO:0045637)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.9 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.7 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.0 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.5 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.6 GO:0090398 cellular senescence(GO:0090398)
0.0 0.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 3.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.0 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.5 GO:0045026 plasma membrane fusion(GO:0045026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.7 2.1 GO:0034657 GID complex(GO:0034657)
0.7 3.3 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.6 2.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.5 7.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 8.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 1.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.4 2.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4 4.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 3.3 GO:0042587 glycogen granule(GO:0042587)
0.3 2.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 1.2 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.2 6.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 8.5 GO:0031519 PcG protein complex(GO:0031519)
0.1 5.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.0 GO:0005916 fascia adherens(GO:0005916)
0.1 4.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.6 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.2 GO:0031906 late endosome lumen(GO:0031906)
0.1 0.9 GO:0000125 PCAF complex(GO:0000125)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 5.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.3 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 9.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 1.1 GO:0046930 pore complex(GO:0046930)
0.0 1.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.8 GO:0001772 immunological synapse(GO:0001772)
0.0 5.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 2.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 3.3 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.8 GO:0005604 basement membrane(GO:0005604)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 4.1 GO:0045121 membrane raft(GO:0045121)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.1 GO:0043195 terminal bouton(GO:0043195)
0.0 5.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 16.3 GO:0005794 Golgi apparatus(GO:0005794)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
1.1 4.6 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.9 2.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.7 5.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.7 2.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.6 1.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.6 2.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.5 8.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.5 12.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 1.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.5 5.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.4 2.3 GO:0098821 BMP receptor activity(GO:0098821)
0.4 3.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 6.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 2.5 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.3 6.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 4.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.3 0.8 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.3 0.8 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3 1.0 GO:0035276 ethanol binding(GO:0035276)
0.2 3.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 0.8 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 0.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 0.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.2 2.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 3.4 GO:0005112 Notch binding(GO:0005112)
0.2 1.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.2 2.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 4.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 1.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 21.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 1.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.0 6.3 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 2.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 7.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 1.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 7.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 3.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0005123 death receptor binding(GO:0005123)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 3.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 4.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 12.7 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 7.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 2.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 7.8 PID SHP2 PATHWAY SHP2 signaling
0.1 3.9 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.5 PID RAS PATHWAY Regulation of Ras family activation
0.1 6.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 6.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 9.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 2.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 6.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 5.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 4.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 2.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 3.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 2.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 6.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 3.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 3.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 2.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase