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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AGUGCAA

Z-value: 1.17

Motif logo

logo of

miRNA associated with seed AGUGCAA

NamemiRBASE accession
hsa-miR-130a-3p
MIMAT0000425
hsa-miR-130b-3p
MIMAT0000691
hsa-miR-301a-3p
MIMAT0000688
hsa-miR-301b-3p
MIMAT0004958
hsa-miR-454-3p
MIMAT0003885
hsa-miR-3666
MIMAT0018088
hsa-miR-4295
MIMAT0016844

Activity profile of AGUGCAA motif

Sorted Z-values of AGUGCAA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_10199468 30.51 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr14_-_60097297 24.17 ENST00000395090.1
RTN1
reticulon 1
chr1_-_204380919 23.56 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr8_+_11141925 15.05 ENST00000221086.3
MTMR9
myotubularin related protein 9
chr17_-_78450398 14.80 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr11_-_113746277 14.25 ENST00000003302.4
ENST00000545540.1
USP28
ubiquitin specific peptidase 28
chr3_+_115342159 13.93 ENST00000305124.6
GAP43
growth associated protein 43
chr5_+_71403061 13.77 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr20_+_1246908 13.61 ENST00000381873.3
ENST00000381867.1
SNPH
syntaphilin
chr3_+_50712672 13.46 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr14_-_21493884 13.03 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2
NDRG family member 2
chr19_+_47759716 12.70 ENST00000221922.6
CCDC9
coiled-coil domain containing 9
chr8_-_110660999 12.67 ENST00000424158.2
ENST00000533895.1
ENST00000446070.2
ENST00000528331.1
ENST00000526302.1
ENST00000433638.1
ENST00000408908.2
ENST00000524720.1
SYBU
syntabulin (syntaxin-interacting)
chr8_+_26435359 12.55 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr15_-_83316254 12.45 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr16_-_57318566 11.94 ENST00000569059.1
ENST00000219207.5
PLLP
plasmolipin
chr11_-_45687128 11.83 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr17_-_27278304 11.07 ENST00000577226.1
PHF12
PHD finger protein 12
chr16_+_19125252 10.81 ENST00000566735.1
ENST00000381440.3
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr1_+_84543734 10.75 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr13_+_42846272 10.56 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr2_+_25015968 10.39 ENST00000380834.2
ENST00000473706.1
CENPO
centromere protein O
chr19_-_17799008 10.33 ENST00000519716.2
UNC13A
unc-13 homolog A (C. elegans)
chr22_-_21213029 9.97 ENST00000572273.1
ENST00000255882.6
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr20_-_48532019 9.70 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr15_-_49338748 9.66 ENST00000559471.1
SECISBP2L
SECIS binding protein 2-like
chrX_+_53111541 9.58 ENST00000375442.4
ENST00000579390.1
TSPYL2
TSPY-like 2
chr18_-_65184217 9.21 ENST00000310045.7
DSEL
dermatan sulfate epimerase-like
chr16_+_50775948 9.17 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr20_+_34700333 9.01 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chrX_-_92928557 8.90 ENST00000373079.3
ENST00000475430.2
NAP1L3
nucleosome assembly protein 1-like 3
chr14_+_74111578 8.83 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1
dynein, axonemal, light chain 1
chr11_-_118661828 8.83 ENST00000264018.4
DDX6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr4_-_36246060 8.62 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_113930291 8.47 ENST00000335953.4
ZBTB16
zinc finger and BTB domain containing 16
chr1_+_78245303 8.43 ENST00000370791.3
ENST00000443751.2
FAM73A
family with sequence similarity 73, member A
chr5_-_136834982 8.35 ENST00000510689.1
ENST00000394945.1
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr9_+_99212403 8.33 ENST00000375251.3
ENST00000375249.4
HABP4
hyaluronan binding protein 4
chr17_-_1532106 8.31 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr17_-_17875688 8.21 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr11_+_92085262 8.18 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr8_+_42752053 8.12 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr11_-_46940074 8.11 ENST00000378623.1
ENST00000534404.1
LRP4
low density lipoprotein receptor-related protein 4
chr11_-_18656028 8.11 ENST00000336349.5
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr2_-_2334888 8.06 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr6_-_154677900 8.05 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr17_-_19771216 7.95 ENST00000395544.4
ULK2
unc-51 like autophagy activating kinase 2
chr10_-_124768300 7.91 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr13_+_53226963 7.90 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SUGT1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr5_-_138210977 7.82 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chrX_-_54384425 7.77 ENST00000375169.3
ENST00000354646.2
WNK3
WNK lysine deficient protein kinase 3
chr3_-_18466787 7.72 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chrX_-_18372792 7.65 ENST00000251900.4
SCML2
sex comb on midleg-like 2 (Drosophila)
chr15_+_31619013 7.62 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr10_-_102279586 7.61 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31B
SEC31 homolog B (S. cerevisiae)
chr1_-_109584608 7.61 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47
WD repeat domain 47
chr10_+_92980517 7.35 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr10_-_73611046 7.26 ENST00000394934.1
ENST00000394936.3
PSAP
prosaposin
chr4_+_55524085 7.23 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr6_-_136871957 7.22 ENST00000354570.3
MAP7
microtubule-associated protein 7
chr18_-_53255766 7.12 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr1_-_52831796 7.10 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
CC2D1B
coiled-coil and C2 domain containing 1B
chr10_-_81205373 6.94 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr4_+_139936905 6.91 ENST00000280614.2
CCRN4L
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr6_+_56954867 6.65 ENST00000370708.4
ENST00000370702.1
ZNF451
zinc finger protein 451
chr20_+_57267669 6.60 ENST00000356091.6
NPEPL1
aminopeptidase-like 1
chr2_+_70142189 6.55 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr2_+_173600671 6.49 ENST00000409036.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr8_-_53322303 6.45 ENST00000276480.7
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr11_-_108093329 6.44 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr2_+_203879568 6.40 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chr8_+_27631903 6.36 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr1_-_226924980 6.35 ENST00000272117.3
ITPKB
inositol-trisphosphate 3-kinase B
chr14_-_50698276 6.20 ENST00000216373.5
SOS2
son of sevenless homolog 2 (Drosophila)
chr7_+_138916231 6.15 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr7_+_94139105 6.14 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr2_+_149632783 6.14 ENST00000435030.1
KIF5C
kinesin family member 5C
chr1_+_11866207 6.06 ENST00000312413.6
ENST00000346436.6
CLCN6
chloride channel, voltage-sensitive 6
chr19_-_10341948 5.92 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
S1PR2
DNMT1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr11_-_74109422 5.81 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr10_+_76871454 5.67 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr3_+_4535025 5.61 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr2_+_173940442 5.59 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr5_+_7396141 5.58 ENST00000338316.4
ADCY2
adenylate cyclase 2 (brain)
chr9_+_100263912 5.53 ENST00000259365.4
TMOD1
tropomodulin 1
chr10_+_96162242 5.49 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr5_-_65017921 5.47 ENST00000381007.4
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr17_+_16284104 5.35 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
UBB
ubiquitin B
chr13_+_49822041 5.29 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
CDADC1
cytidine and dCMP deaminase domain containing 1
chr1_-_51984908 5.25 ENST00000371730.2
EPS15
epidermal growth factor receptor pathway substrate 15
chr2_-_86564776 5.24 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr6_+_44238203 5.16 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr1_-_95538492 5.14 ENST00000370205.5
ALG14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr3_-_66551351 5.13 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr17_-_61777459 5.10 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr13_-_36920420 5.03 ENST00000438666.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr1_+_97187318 4.94 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr6_+_121756809 4.84 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr3_-_178790057 4.82 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr10_-_104178857 4.77 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr14_-_96830207 4.76 ENST00000359933.4
ATG2B
autophagy related 2B
chr7_-_139876812 4.67 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chr2_-_101767715 4.63 ENST00000376840.4
ENST00000409318.1
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr2_+_177053307 4.62 ENST00000331462.4
HOXD1
homeobox D1
chr18_+_54318616 4.61 ENST00000254442.3
WDR7
WD repeat domain 7
chr2_-_68694390 4.60 ENST00000377957.3
FBXO48
F-box protein 48
chr1_+_28099683 4.60 ENST00000373943.4
STX12
syntaxin 12
chr14_+_57857262 4.58 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr5_-_133512683 4.56 ENST00000353411.6
SKP1
S-phase kinase-associated protein 1
chr12_+_120105558 4.53 ENST00000229328.5
ENST00000541640.1
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr4_+_86396265 4.53 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr11_+_14665263 4.50 ENST00000282096.4
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr18_+_9136758 4.41 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr22_+_50781723 4.40 ENST00000359139.3
ENST00000395741.3
ENST00000395744.3
PPP6R2
protein phosphatase 6, regulatory subunit 2
chr2_-_27718052 4.40 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr11_-_31839488 4.31 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6
paired box 6
chr9_-_79520989 4.26 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2
prune homolog 2 (Drosophila)
chr14_-_75593708 4.25 ENST00000557673.1
ENST00000238616.5
NEK9
NIMA-related kinase 9
chr20_+_44657845 4.22 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr17_+_53342311 4.21 ENST00000226067.5
HLF
hepatic leukemia factor
chr4_+_153701081 4.09 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1
ADP-ribosylation factor interacting protein 1
chr2_-_69870835 4.04 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr1_-_38019878 4.03 ENST00000296215.6
SNIP1
Smad nuclear interacting protein 1
chr20_-_48099182 3.99 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr9_-_135819987 3.99 ENST00000298552.3
ENST00000403810.1
TSC1
tuberous sclerosis 1
chr2_-_47403642 3.96 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
CALM2
calmodulin 2 (phosphorylase kinase, delta)
chr10_+_126490354 3.95 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr9_-_136857403 3.89 ENST00000406606.3
ENST00000371850.3
VAV2
vav 2 guanine nucleotide exchange factor
chr11_-_46722117 3.88 ENST00000311956.4
ARHGAP1
Rho GTPase activating protein 1
chr17_+_54911444 3.87 ENST00000284061.3
ENST00000572810.1
DGKE
diacylglycerol kinase, epsilon 64kDa
chr8_-_93115445 3.86 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_148663729 3.85 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr7_-_5821314 3.77 ENST00000425013.2
ENST00000389902.3
RNF216
ring finger protein 216
chr3_+_37493610 3.74 ENST00000264741.5
ITGA9
integrin, alpha 9
chr14_+_103851712 3.73 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr13_+_42622781 3.63 ENST00000337343.4
ENST00000261491.5
ENST00000379274.2
DGKH
diacylglycerol kinase, eta
chr3_-_114790179 3.63 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_36022979 3.60 ENST00000469892.1
ENST00000325722.3
KIAA0319L
KIAA0319-like
chr17_-_42580738 3.60 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
GPATCH8
G patch domain containing 8
chr2_+_241508039 3.53 ENST00000270357.4
RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr19_-_4066890 3.53 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr4_-_53525406 3.52 ENST00000451218.2
ENST00000441222.3
USP46
ubiquitin specific peptidase 46
chrX_-_153363188 3.52 ENST00000303391.6
MECP2
methyl CpG binding protein 2 (Rett syndrome)
chr17_+_41132564 3.45 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr2_-_213403565 3.45 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr15_-_64648273 3.44 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
CSNK1G1
casein kinase 1, gamma 1
chr20_+_8112824 3.38 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr20_+_4666882 3.34 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr6_+_96463840 3.31 ENST00000302103.5
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr1_+_151584544 3.28 ENST00000458013.2
ENST00000368843.3
SNX27
sorting nexin family member 27
chr5_-_107006596 3.25 ENST00000333274.6
EFNA5
ephrin-A5
chr18_+_10454594 3.23 ENST00000355285.5
APCDD1
adenomatosis polyposis coli down-regulated 1
chr9_-_91793675 3.22 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr5_-_32313019 3.18 ENST00000280285.5
ENST00000264934.5
MTMR12
myotubularin related protein 12
chr13_+_111365602 3.18 ENST00000333219.7
ING1
inhibitor of growth family, member 1
chr1_-_6240183 3.17 ENST00000262450.3
ENST00000378021.1
CHD5
chromodomain helicase DNA binding protein 5
chr4_+_115519577 3.07 ENST00000310836.6
UGT8
UDP glycosyltransferase 8
chr18_+_46065393 3.04 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr21_+_45285050 2.99 ENST00000291572.8
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr10_-_735553 2.96 ENST00000280886.6
ENST00000423550.1
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr12_+_108908962 2.91 ENST00000552695.1
ENST00000552758.1
ENST00000361549.2
FICD
FIC domain containing
chr13_-_21476900 2.90 ENST00000400602.2
ENST00000255305.6
XPO4
exportin 4
chr6_-_111136513 2.89 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr15_-_34502278 2.88 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
KATNBL1
katanin p80 subunit B-like 1
chr6_-_88876058 2.83 ENST00000369501.2
CNR1
cannabinoid receptor 1 (brain)
chr3_-_53080047 2.82 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr12_-_26278030 2.82 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr3_+_57261743 2.81 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr2_-_182545603 2.81 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr6_+_69345166 2.81 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr11_+_33278811 2.78 ENST00000303296.4
ENST00000379016.3
HIPK3
homeodomain interacting protein kinase 3
chr14_-_91526922 2.78 ENST00000418736.2
ENST00000261991.3
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr10_+_86088381 2.77 ENST00000224756.8
ENST00000372088.2
CCSER2
coiled-coil serine-rich protein 2
chr1_+_12290121 2.77 ENST00000358136.3
ENST00000356315.4
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr17_+_47865917 2.76 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
KAT7
K(lysine) acetyltransferase 7
chr6_-_91006461 2.76 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr11_-_30038490 2.75 ENST00000328224.6
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr17_-_62340581 2.74 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
TEX2
testis expressed 2
chr13_-_95364389 2.73 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr18_+_13218769 2.71 ENST00000399848.3
ENST00000361205.4
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr17_+_41177220 2.65 ENST00000587250.2
ENST00000544533.1
RND2
Rho family GTPase 2
chr17_+_5031687 2.60 ENST00000250066.6
ENST00000304328.5
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr22_-_22221900 2.60 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1
chr4_-_122854612 2.59 ENST00000264811.5
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr9_-_27529726 2.58 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr12_-_51611477 2.57 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr17_-_4167142 2.56 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr10_-_1779663 2.54 ENST00000381312.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr16_-_18812746 2.51 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ARL6IP1
RP11-1035H13.3
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr5_-_160973649 2.51 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr18_+_43914159 2.48 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165
ring finger protein 165
chr7_-_123389104 2.48 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chr2_-_70780770 2.48 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr6_+_46097711 2.43 ENST00000321037.4
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr16_-_69419871 2.42 ENST00000603068.1
ENST00000254942.3
ENST00000567296.2
TERF2
telomeric repeat binding factor 2
chr10_-_126432619 2.40 ENST00000337318.3
FAM53B
family with sequence similarity 53, member B
chr17_-_56406117 2.35 ENST00000268893.6
ENST00000355701.3
BZRAP1
benzodiazepine receptor (peripheral) associated protein 1
chr1_+_101702417 2.33 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr8_+_59323823 2.33 ENST00000399598.2
UBXN2B
UBX domain protein 2B
chr12_+_54402790 2.33 ENST00000040584.4
HOXC8
homeobox C8

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGCAA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 30.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
3.1 9.2 GO:1990108 protein linear deubiquitination(GO:1990108)
2.9 8.8 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.8 8.4 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
2.7 8.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
2.6 23.6 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
2.6 10.3 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
2.1 10.7 GO:0097338 response to clozapine(GO:0097338)
2.0 8.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
1.9 7.8 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
1.8 5.4 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
1.8 3.5 GO:0045925 positive regulation of female receptivity(GO:0045925)
1.7 5.1 GO:0032474 otolith morphogenesis(GO:0032474)
1.7 8.5 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.5 5.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
1.4 11.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.4 5.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
1.3 4.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
1.3 7.9 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.3 3.9 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
1.3 5.0 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
1.2 13.6 GO:0016081 synaptic vesicle docking(GO:0016081)
1.2 4.8 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.2 11.9 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
1.2 3.5 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
1.2 11.7 GO:0016198 axon choice point recognition(GO:0016198)
1.1 3.4 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
1.1 7.9 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
1.1 3.4 GO:0090427 activation of meiosis(GO:0090427)
1.1 3.3 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
1.1 4.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.0 7.0 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
1.0 3.8 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.9 9.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.9 2.8 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.9 5.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.9 8.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.9 1.8 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.9 17.6 GO:0006012 galactose metabolic process(GO:0006012)
0.9 9.7 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.9 2.6 GO:0019858 cytosine metabolic process(GO:0019858)
0.9 4.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.8 6.7 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.8 13.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.8 2.4 GO:0031627 telomeric loop formation(GO:0031627) negative regulation of t-circle formation(GO:1904430)
0.8 4.0 GO:0051029 rRNA transport(GO:0051029)
0.8 2.4 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.8 2.3 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.8 13.8 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.8 4.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.7 8.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.7 8.8 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.7 5.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.7 2.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.7 2.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.7 6.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.7 2.0 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.7 7.8 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.6 9.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.6 1.9 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.6 2.5 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.6 1.2 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.6 9.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.6 2.8 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.6 2.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.5 1.1 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.5 2.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.5 8.0 GO:0015671 oxygen transport(GO:0015671)
0.5 2.1 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.5 2.0 GO:2000672 regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 1.5 GO:0070253 somatostatin secretion(GO:0070253)
0.5 0.5 GO:0021571 rhombomere 5 development(GO:0021571)
0.5 7.8 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.5 1.4 GO:0001923 B-1 B cell differentiation(GO:0001923) B cell proliferation involved in immune response(GO:0002322)
0.5 3.3 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.5 3.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.5 4.6 GO:0010265 SCF complex assembly(GO:0010265)
0.5 3.2 GO:0098532 spermatogenesis, exchange of chromosomal proteins(GO:0035093) histone H3-K27 trimethylation(GO:0098532)
0.5 1.8 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.5 4.5 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.4 1.8 GO:0006408 snRNA export from nucleus(GO:0006408)
0.4 3.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.4 2.6 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.4 2.6 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.4 0.4 GO:0007506 gonadal mesoderm development(GO:0007506)
0.4 11.0 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.4 3.5 GO:0008343 adult feeding behavior(GO:0008343)
0.4 1.9 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.4 2.2 GO:0051012 microtubule sliding(GO:0051012)
0.4 9.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.4 1.8 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.4 1.1 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.3 0.3 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.3 2.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.3 6.5 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.3 10.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3 2.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 1.0 GO:1904954 Spemann organizer formation(GO:0060061) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.3 1.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 2.2 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.3 0.9 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 8.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.3 6.5 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.3 4.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.3 1.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 2.0 GO:0042426 choline catabolic process(GO:0042426)
0.3 3.3 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.3 0.3 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.3 9.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.3 0.8 GO:0060978 angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.3 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.3 4.8 GO:0044804 nucleophagy(GO:0044804)
0.2 6.5 GO:0048665 neuron fate specification(GO:0048665)
0.2 4.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 6.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.2 0.7 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 1.3 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 1.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 3.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 1.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 5.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.2 16.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 1.4 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.2 8.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.2 1.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 4.5 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 4.5 GO:0071168 protein localization to chromatin(GO:0071168)
0.2 18.5 GO:0006334 nucleosome assembly(GO:0006334)
0.2 0.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.2 2.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 4.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 2.8 GO:0001573 ganglioside metabolic process(GO:0001573)
0.2 12.7 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.2 8.3 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.2 0.9 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 1.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 2.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.9 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 1.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.6 GO:0001757 somite specification(GO:0001757)
0.1 1.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 2.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.7 GO:1903974 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of glial cell migration(GO:1903977) positive regulation of microglial cell migration(GO:1904141)
0.1 6.4 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.1 4.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 6.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.8 GO:0006196 AMP catabolic process(GO:0006196)
0.1 2.5 GO:0071420 cellular response to histamine(GO:0071420)
0.1 2.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 11.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 2.8 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 3.9 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.1 5.3 GO:1901998 toxin transport(GO:1901998)
0.1 3.6 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.1 0.7 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 5.8 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 0.4 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 2.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.8 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 2.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 1.3 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.5 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.9 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 1.0 GO:0006907 pinocytosis(GO:0006907)
0.1 0.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 2.4 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 0.2 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 1.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 3.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.3 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 3.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 7.7 GO:0030516 regulation of axon extension(GO:0030516)
0.1 2.9 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 4.3 GO:0033344 cholesterol efflux(GO:0033344)
0.1 0.8 GO:1900016 negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 1.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 2.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 7.3 GO:0006970 response to osmotic stress(GO:0006970)
0.1 1.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 3.5 GO:0043171 peptide catabolic process(GO:0043171)
0.1 4.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 2.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 1.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 4.3 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.1 0.1 GO:0030242 pexophagy(GO:0030242)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 6.9 GO:0051291 protein heterooligomerization(GO:0051291)
0.1 2.4 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 3.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.2 GO:0045116 protein neddylation(GO:0045116)
0.1 2.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 1.2 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 3.7 GO:0030010 establishment of cell polarity(GO:0030010)
0.1 1.1 GO:0001881 receptor recycling(GO:0001881)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.1 GO:0097503 sialylation(GO:0097503)
0.1 1.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 2.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 2.8 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.1 1.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 1.9 GO:0021987 cerebral cortex development(GO:0021987)
0.0 1.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.6 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 4.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 3.8 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.5 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 2.0 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.9 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.5 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.3 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.4 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 30.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
3.4 10.3 GO:0044305 calyx of Held(GO:0044305)
2.8 8.3 GO:0019034 viral replication complex(GO:0019034)
2.0 8.1 GO:0070695 FHF complex(GO:0070695)
2.0 13.9 GO:0032584 growth cone membrane(GO:0032584)
1.4 23.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.3 3.9 GO:0097443 sorting endosome(GO:0097443)
1.3 8.8 GO:0001520 outer dense fiber(GO:0001520)
1.1 4.6 GO:0031417 NatC complex(GO:0031417)
1.1 8.8 GO:0036157 outer dynein arm(GO:0036157)
1.0 4.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.9 4.7 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.8 6.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.8 10.3 GO:0097433 dense body(GO:0097433)
0.8 13.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.7 2.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.6 8.1 GO:0016600 flotillin complex(GO:0016600)
0.6 5.6 GO:0005955 calcineurin complex(GO:0005955)
0.6 1.7 GO:0034657 GID complex(GO:0034657)
0.5 10.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.5 11.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.5 4.6 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.5 6.1 GO:0035253 ciliary rootlet(GO:0035253)
0.5 3.3 GO:0071203 WASH complex(GO:0071203)
0.5 12.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.4 1.3 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.4 2.5 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.4 6.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 4.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 4.8 GO:0005916 fascia adherens(GO:0005916)
0.4 1.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.3 2.4 GO:0030870 Mre11 complex(GO:0030870)
0.3 2.6 GO:0002080 acrosomal membrane(GO:0002080)
0.3 4.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 11.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.3 7.1 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.3 20.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 0.9 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.3 8.4 GO:0033268 node of Ranvier(GO:0033268)
0.3 5.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.3 1.4 GO:0031905 early endosome lumen(GO:0031905)
0.3 4.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 6.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 5.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 5.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 7.2 GO:0042629 mast cell granule(GO:0042629)
0.2 1.0 GO:0097422 tubular endosome(GO:0097422)
0.2 0.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 4.4 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2 2.5 GO:0030478 actin cap(GO:0030478)
0.2 17.9 GO:0000776 kinetochore(GO:0000776)
0.2 5.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 3.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.0 GO:0035371 microtubule plus-end(GO:0035371)
0.1 4.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 5.5 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.0 GO:0032433 filopodium tip(GO:0032433)
0.1 21.2 GO:0005875 microtubule associated complex(GO:0005875)
0.1 1.0 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 2.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.6 GO:1990752 microtubule end(GO:1990752)
0.1 0.7 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 5.2 GO:0030120 vesicle coat(GO:0030120)
0.1 2.6 GO:0031143 pseudopodium(GO:0031143)
0.1 1.2 GO:0060077 inhibitory synapse(GO:0060077)
0.1 3.7 GO:0008305 integrin complex(GO:0008305)
0.1 7.3 GO:0043195 terminal bouton(GO:0043195)
0.1 0.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 2.1 GO:0071141 SMAD protein complex(GO:0071141)
0.1 2.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 11.0 GO:0016605 PML body(GO:0016605)
0.1 1.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 3.3 GO:0031519 PcG protein complex(GO:0031519)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.1 4.1 GO:0005811 lipid particle(GO:0005811)
0.1 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 4.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 1.4 GO:0043218 compact myelin(GO:0043218)
0.1 11.2 GO:0032993 protein-DNA complex(GO:0032993)
0.1 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 6.6 GO:0005923 bicellular tight junction(GO:0005923)
0.1 8.1 GO:0055037 recycling endosome(GO:0055037)
0.0 2.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 3.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 4.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 5.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 11.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.8 GO:0015030 Cajal body(GO:0015030)
0.0 7.8 GO:0030017 sarcomere(GO:0030017)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 5.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.3 GO:0098793 presynapse(GO:0098793)
0.0 4.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.8 GO:0000922 spindle pole(GO:0000922)
0.0 4.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.9 GO:0043204 perikaryon(GO:0043204)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 2.3 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.4 GO:0002102 podosome(GO:0002102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
3.1 9.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
2.2 67.1 GO:0017075 syntaxin-1 binding(GO:0017075)
1.9 3.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
1.9 5.7 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.7 11.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.7 10.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.6 9.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
1.5 4.5 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
1.4 5.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.4 13.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
1.3 6.7 GO:0061665 SUMO ligase activity(GO:0061665)
1.3 6.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.2 15.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
1.1 3.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.1 9.6 GO:0000182 rDNA binding(GO:0000182)
1.1 6.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.0 11.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.0 11.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.0 5.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.0 5.8 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.9 2.8 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.9 9.2 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.9 7.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.8 10.7 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.8 13.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.8 4.8 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.8 3.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.7 8.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.7 7.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.7 10.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.6 8.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.6 7.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.6 6.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.6 3.3 GO:1903135 cupric ion binding(GO:1903135)
0.6 1.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.5 7.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 3.8 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.5 1.5 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
0.5 4.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.5 2.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.4 2.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 8.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.4 1.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.4 7.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 3.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 2.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 11.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 4.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.4 8.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.4 2.2 GO:0005499 vitamin D binding(GO:0005499)
0.4 3.5 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.3 5.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 3.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 6.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 2.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 4.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 1.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3 0.9 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.3 8.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.3 4.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 2.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 8.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 5.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.3 1.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 22.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 1.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 5.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 7.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 3.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.2 1.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 4.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 2.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 5.5 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.0 GO:0034452 dynactin binding(GO:0034452)
0.2 11.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 3.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.2 8.4 GO:0030552 cAMP binding(GO:0030552)
0.2 2.8 GO:0043422 protein kinase B binding(GO:0043422)
0.2 0.9 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 2.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 2.8 GO:0030955 potassium ion binding(GO:0030955)
0.2 2.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 1.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 4.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 4.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 2.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 3.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 6.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.2 3.2 GO:0019208 phosphatase regulator activity(GO:0019208)
0.2 3.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.2 6.3 GO:0070412 R-SMAD binding(GO:0070412)
0.2 2.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.7 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 1.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 22.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 5.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.0 GO:0016015 morphogen activity(GO:0016015)
0.1 1.8 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 1.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 8.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.1 3.7 GO:0043236 laminin binding(GO:0043236)
0.1 2.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 1.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 6.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 4.5 GO:0070888 E-box binding(GO:0070888)
0.1 1.1 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 1.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 4.9 GO:0030276 clathrin binding(GO:0030276)
0.1 3.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 8.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 6.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 2.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 17.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.4 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 2.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 4.8 GO:0002039 p53 binding(GO:0002039)
0.1 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 3.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 2.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 7.7 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.6 6.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 10.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.4 21.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 16.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 16.9 PID ARF6 PATHWAY Arf6 signaling events
0.3 6.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 10.7 PID IL3 PATHWAY IL3-mediated signaling events
0.3 4.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.3 10.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.2 11.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 5.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 6.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 7.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 6.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 8.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 9.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 3.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.2 ST GA12 PATHWAY G alpha 12 Pathway
0.1 5.4 PID AURORA A PATHWAY Aurora A signaling
0.1 1.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.1 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 7.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.8 PID IFNG PATHWAY IFN-gamma pathway
0.1 2.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 4.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 5.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 3.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 3.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 30.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.0 4.9 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.5 7.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5 5.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.5 9.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.4 8.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4 10.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 3.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 5.8 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.3 10.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 4.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.3 6.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.3 7.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 4.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 5.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 4.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 2.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 10.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.2 5.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 9.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 9.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 7.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 2.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 4.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 10.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 7.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 4.5 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.1 9.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 7.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 2.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 3.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 3.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 2.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 12.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 5.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 4.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 10.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 3.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 3.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 5.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 1.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 2.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.2 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling