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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ARNT

Z-value: 3.04

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Transcription factors associated with ARNT

Gene Symbol Gene ID Gene Info
ENSG00000143437.16 aryl hydrocarbon receptor nuclear translocator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARNThg19_v2_chr1_-_150849047_150849085,
hg19_v2_chr1_-_150849174_150849200
-0.342.5e-07Click!

Activity profile of ARNT motif

Sorted Z-values of ARNT motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_77359671 113.67 ENST00000373316.4
phosphoglycerate kinase 1
chrX_+_77359726 110.68 ENST00000442431.1
phosphoglycerate kinase 1
chr11_-_64014379 102.48 ENST00000309318.3
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_-_8939265 94.11 ENST00000489867.1
enolase 1, (alpha)
chr2_-_10587897 86.02 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chrX_+_23685653 78.85 ENST00000379331.3
peroxiredoxin 4
chrX_+_23685563 69.12 ENST00000379341.4
peroxiredoxin 4
chr17_-_47492164 64.01 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
prohibitin
chr3_-_195808980 59.39 ENST00000360110.4
transferrin receptor
chr19_+_50180507 59.12 ENST00000454376.2
ENST00000524771.1
protein arginine methyltransferase 1
chr2_+_201170770 57.78 ENST00000409988.3
ENST00000409385.1
spermatogenesis associated, serine-rich 2-like
chr3_-_195808952 57.60 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
transferrin receptor
chr2_+_201171372 57.57 ENST00000409140.3
spermatogenesis associated, serine-rich 2-like
chr1_-_159894319 56.22 ENST00000320307.4
transgelin 2
chr19_-_10530784 55.93 ENST00000593124.1
cell division cycle 37
chr15_+_52311398 55.36 ENST00000261845.5
mitogen-activated protein kinase 6
chr1_-_8938736 52.15 ENST00000234590.4
enolase 1, (alpha)
chr19_+_50180409 51.15 ENST00000391851.4
protein arginine methyltransferase 1
chr12_-_58146128 50.89 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr12_-_58146048 48.68 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr15_+_40453204 47.84 ENST00000287598.6
ENST00000412359.3
BUB1 mitotic checkpoint serine/threonine kinase B
chr7_+_100464760 46.06 ENST00000200457.4
thyroid hormone receptor interactor 6
chr19_+_50180317 44.92 ENST00000534465.1
protein arginine methyltransferase 1
chr3_-_49066811 43.45 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr2_+_216176540 42.31 ENST00000236959.9
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr2_+_216176761 42.25 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr15_+_74218787 41.87 ENST00000261921.7
lysyl oxidase-like 1
chr17_-_5342380 41.19 ENST00000225698.4
complement component 1, q subcomponent binding protein
chr3_-_149688655 41.17 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr1_-_43638168 40.39 ENST00000431635.2
EBNA1 binding protein 2
chr11_+_18416103 39.36 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
lactate dehydrogenase A
chr11_-_122931881 39.07 ENST00000526110.1
ENST00000227378.3
heat shock 70kDa protein 8
chrX_-_16887963 38.42 ENST00000380084.4
retinoblastoma binding protein 7
chr12_-_120907374 38.41 ENST00000550458.1
serine/arginine-rich splicing factor 9
chr6_+_34204642 37.87 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr17_-_48474828 37.57 ENST00000576448.1
ENST00000225972.7
leucine rich repeat containing 59
chr7_+_56119323 37.38 ENST00000275603.4
ENST00000335503.3
ENST00000540286.1
chaperonin containing TCP1, subunit 6A (zeta 1)
chrX_+_69509927 37.25 ENST00000374403.3
kinesin family member 4A
chr7_-_6523688 36.85 ENST00000490996.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_+_18416133 36.68 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
lactate dehydrogenase A
chr1_-_26232951 36.15 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr6_-_8102714 36.01 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr1_+_19578033 35.94 ENST00000330263.4
mRNA turnover 4 homolog (S. cerevisiae)
chr12_+_64798095 35.87 ENST00000332707.5
exportin, tRNA
chr17_-_40075219 35.54 ENST00000537919.1
ENST00000352035.2
ENST00000353196.1
ENST00000393896.2
ATP citrate lyase
chr9_+_112542591 35.15 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr17_-_47492236 35.08 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
prohibitin
chr11_-_64013663 34.67 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_-_149688896 34.66 ENST00000239940.7
profilin 2
chr12_-_120907459 34.16 ENST00000229390.3
serine/arginine-rich splicing factor 9
chr20_+_56964253 33.12 ENST00000395802.3
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr2_+_201171064 32.93 ENST00000451764.2
spermatogenesis associated, serine-rich 2-like
chr5_-_131563501 32.92 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
prolyl 4-hydroxylase, alpha polypeptide II
chr17_+_36908984 32.65 ENST00000225426.4
ENST00000579088.1
proteasome (prosome, macropain) subunit, beta type, 3
chr3_+_52719936 32.62 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr22_+_20105259 31.96 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr14_+_56046990 31.87 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
kinectin 1 (kinesin receptor)
chr3_+_5020801 31.80 ENST00000256495.3
basic helix-loop-helix family, member e40
chr19_-_47353547 31.75 ENST00000601498.1
adaptor-related protein complex 2, sigma 1 subunit
chr17_+_49337881 31.62 ENST00000225298.7
UTP18 small subunit (SSU) processome component homolog (yeast)
chr5_+_170814803 31.37 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr7_-_6523755 31.19 ENST00000436575.1
ENST00000258739.4
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_-_6704513 30.75 ENST00000532203.1
ENST00000288937.6
mitochondrial ribosomal protein L17
chr1_-_43637915 30.14 ENST00000236051.2
EBNA1 binding protein 2
chr12_+_120907622 30.08 ENST00000392509.2
ENST00000549649.1
ENST00000548342.1
dynein, light chain, LC8-type 1
chr12_+_131356582 30.05 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
RAN, member RAS oncogene family
chr15_+_79603404 29.95 ENST00000299705.5
transmembrane emp24 protein transport domain containing 3
chr12_+_6977258 29.70 ENST00000488464.2
ENST00000535434.1
ENST00000493987.1
triosephosphate isomerase 1
chr5_+_34656569 29.69 ENST00000428746.2
retinoic acid induced 14
chr16_+_3070356 29.55 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
tumor necrosis factor receptor superfamily, member 12A
chr14_-_64010046 29.49 ENST00000337537.3
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr16_+_3070313 29.21 ENST00000326577.4
tumor necrosis factor receptor superfamily, member 12A
chr3_-_57583185 29.10 ENST00000463880.1
ADP-ribosylation factor 4
chr4_+_57301896 29.02 ENST00000514888.1
ENST00000264221.2
ENST00000505164.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr17_-_73178599 28.93 ENST00000578238.1
small ubiquitin-like modifier 2
chr3_-_145878954 28.92 ENST00000282903.5
ENST00000360060.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr12_-_50677255 28.88 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIM domain and actin binding 1
chr5_+_68530668 28.84 ENST00000506563.1
cyclin-dependent kinase 7
chr1_-_26233423 28.67 ENST00000357865.2
stathmin 1
chr14_+_56046914 28.39 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
kinectin 1 (kinesin receptor)
chr13_+_27998681 28.22 ENST00000381140.4
general transcription factor IIIA
chr9_+_112542572 28.13 ENST00000374530.3
PALM2-AKAP2 readthrough
chr6_-_43197189 28.11 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr20_-_49547910 28.02 ENST00000396032.3
activity-dependent neuroprotector homeobox
chr8_-_102218292 28.00 ENST00000518336.1
ENST00000520454.1
zinc finger protein 706
chr11_+_844067 27.70 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
tetraspanin 4
chr19_-_47354023 27.61 ENST00000601649.1
ENST00000599990.1
ENST00000352203.4
adaptor-related protein complex 2, sigma 1 subunit
chr5_+_34656331 27.56 ENST00000265109.3
retinoic acid induced 14
chr1_+_47799446 26.99 ENST00000371873.5
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr9_-_2844058 26.98 ENST00000397885.2
KIAA0020
chr14_+_62162258 26.69 ENST00000337138.4
ENST00000394997.1
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr3_+_100211412 25.79 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
transmembrane protein 45A
chr3_-_185542817 25.72 ENST00000382199.2
insulin-like growth factor 2 mRNA binding protein 2
chr19_-_291133 25.72 ENST00000327790.3
phosphatidic acid phosphatase type 2C
chr19_-_40336969 25.65 ENST00000599134.1
ENST00000597634.1
ENST00000598417.1
ENST00000601274.1
ENST00000594309.1
ENST00000221801.3
fibrillarin
chr2_-_179315490 25.58 ENST00000487082.1
protein kinase, interferon-inducible double stranded RNA dependent activator
chr14_-_54908043 25.49 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
cornichon family AMPA receptor auxiliary protein 1
chr2_+_187350883 25.49 ENST00000337859.6
zinc finger CCCH-type containing 15
chr5_+_138609441 25.35 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
matrin 3
chr7_+_6048856 25.26 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chrX_+_153672468 25.11 ENST00000393600.3
family with sequence similarity 50, member A
chr3_-_185542761 25.09 ENST00000457616.2
ENST00000346192.3
insulin-like growth factor 2 mRNA binding protein 2
chr19_-_47354082 25.02 ENST00000593442.1
ENST00000263270.6
adaptor-related protein complex 2, sigma 1 subunit
chr18_+_9913977 25.02 ENST00000400000.2
ENST00000340541.4
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr13_-_31038370 24.93 ENST00000399489.1
ENST00000339872.4
high mobility group box 1
chr12_+_6643676 24.81 ENST00000396856.1
ENST00000396861.1
glyceraldehyde-3-phosphate dehydrogenase
chr1_+_87170577 24.78 ENST00000482504.1
SH3-domain GRB2-like endophilin B1
chr2_+_198365122 24.71 ENST00000604458.1
HSPE1-MOB4 readthrough
chr16_-_81129845 24.53 ENST00000569885.1
ENST00000566566.1
glycine cleavage system protein H (aminomethyl carrier)
chr1_-_6269448 24.37 ENST00000465335.1
ribosomal protein L22
chr5_+_49962495 24.35 ENST00000515175.1
poly (ADP-ribose) polymerase family, member 8
chr15_-_65282232 24.18 ENST00000416889.2
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr1_-_6269304 24.15 ENST00000471204.1
ribosomal protein L22
chr6_-_7313381 23.98 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
signal sequence receptor, alpha
chr17_+_40985407 23.63 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr20_+_31407692 23.21 ENST00000375571.5
microtubule-associated protein, RP/EB family, member 1
chr4_-_39529049 23.19 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UDP-glucose 6-dehydrogenase
chr15_+_45315302 23.10 ENST00000267814.9
sorbitol dehydrogenase
chr1_-_6259613 23.06 ENST00000465387.1
ribosomal protein L22
chr22_+_24236191 23.02 ENST00000215754.7
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr11_-_118972575 22.95 ENST00000432443.2
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr3_+_122785895 22.82 ENST00000316218.7
protein disulfide isomerase family A, member 5
chr1_-_26232522 22.79 ENST00000399728.1
stathmin 1
chr1_-_43833628 22.55 ENST00000413844.2
ENST00000372458.3
ELOVL fatty acid elongase 1
chr17_+_7476136 22.50 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr15_-_65282274 22.49 ENST00000204566.2
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr2_+_113403434 22.37 ENST00000272542.3
solute carrier family 20 (phosphate transporter), member 1
chr7_+_100303676 22.36 ENST00000303151.4
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr22_-_30987849 22.35 ENST00000402284.3
ENST00000354694.7
pescadillo ribosomal biogenesis factor 1
chr11_+_60609537 22.34 ENST00000227520.5
coiled-coil domain containing 86
chr10_-_103543145 22.24 ENST00000370110.5
nucleophosmin/nucleoplasmin 3
chr11_-_118927816 22.03 ENST00000534233.1
ENST00000532752.1
ENST00000525859.1
ENST00000404233.3
ENST00000532421.1
ENST00000543287.1
ENST00000527310.2
ENST00000529972.1
hypoxia up-regulated 1
chr5_+_95066823 21.63 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr6_-_114292449 21.59 ENST00000519065.1
histone deacetylase 2
chr11_+_69455855 21.55 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr12_-_21810726 21.53 ENST00000396076.1
lactate dehydrogenase B
chr2_+_118572226 21.44 ENST00000263239.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr8_+_126442563 21.25 ENST00000311922.3
tribbles pseudokinase 1
chr1_-_86174065 20.96 ENST00000370574.3
ENST00000431532.2
zinc finger, HIT-type containing 6
chr6_+_44191507 20.91 ENST00000371724.1
ENST00000371713.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr1_+_230202936 20.91 ENST00000366672.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr2_-_179315453 20.85 ENST00000432031.2
protein kinase, interferon-inducible double stranded RNA dependent activator
chr12_-_21810765 20.77 ENST00000450584.1
ENST00000350669.1
lactate dehydrogenase B
chr19_-_14628645 20.57 ENST00000598235.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr5_-_176943917 20.47 ENST00000330503.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
chr3_+_38179969 20.43 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
myeloid differentiation primary response 88
chr6_-_17706618 20.30 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chr15_-_65281775 19.89 ENST00000433215.2
ENST00000558415.1
ENST00000557795.1
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr3_-_149688502 19.87 ENST00000481767.1
ENST00000475518.1
profilin 2
chr12_-_106641728 19.85 ENST00000378026.4
cytoskeleton-associated protein 4
chr5_+_138609782 19.85 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
matrin 3
chr16_-_88851618 19.72 ENST00000301015.9
piezo-type mechanosensitive ion channel component 1
chr2_-_98612350 19.53 ENST00000186436.5
transmembrane protein 131
chr12_+_3069037 19.25 ENST00000397122.2
TEA domain family member 4
chr1_+_193091080 19.21 ENST00000367435.3
cell division cycle 73
chr3_+_100428268 18.94 ENST00000240851.4
TRK-fused gene
chr3_+_133292574 18.93 ENST00000264993.3
CDV3 homolog (mouse)
chr3_+_100428316 18.88 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TRK-fused gene
chr6_-_33385854 18.83 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr2_+_48010312 18.75 ENST00000540021.1
mutS homolog 6
chr22_-_30987837 18.58 ENST00000335214.6
pescadillo ribosomal biogenesis factor 1
chr3_+_100428188 18.50 ENST00000418917.2
ENST00000490574.1
TRK-fused gene
chr12_+_57623477 18.48 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr2_+_75061108 18.47 ENST00000290573.2
hexokinase 2
chr1_+_100436065 18.33 ENST00000370153.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr3_+_25831567 18.25 ENST00000280701.3
ENST00000420173.2
3-oxoacyl-ACP synthase, mitochondrial
chr6_+_30539153 18.19 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ATP-binding cassette, sub-family F (GCN20), member 1
chr19_+_1407517 17.98 ENST00000336761.6
ENST00000233078.4
DAZ associated protein 1
chr22_+_42017123 17.81 ENST00000360079.3
X-ray repair complementing defective repair in Chinese hamster cells 6
chr15_+_96875657 17.75 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr11_+_125462690 17.72 ENST00000392708.4
ENST00000529196.1
ENST00000531491.1
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr1_+_214454492 17.70 ENST00000366957.5
ENST00000415093.2
SET and MYND domain containing 2
chr19_-_29704448 17.69 ENST00000304863.4
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr4_-_39529180 17.54 ENST00000515021.1
ENST00000510490.1
ENST00000316423.6
UDP-glucose 6-dehydrogenase
chr19_+_17622415 17.38 ENST00000252603.2
ENST00000600923.1
6-phosphogluconolactonase
chr3_-_50329990 17.30 ENST00000417626.2
interferon-related developmental regulator 2
chr2_+_198365095 17.20 ENST00000409468.1
heat shock 10kDa protein 1
chr11_+_6624970 17.11 ENST00000420936.2
ENST00000528995.1
integrin-linked kinase
chr1_+_26496362 16.97 ENST00000374266.5
ENST00000270812.5
zinc finger protein 593
chr1_-_87379785 16.85 ENST00000401030.3
ENST00000370554.1
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr11_+_6624955 16.82 ENST00000299421.4
ENST00000537806.1
integrin-linked kinase
chr6_+_44191290 16.80 ENST00000371755.3
ENST00000371740.5
ENST00000371731.1
ENST00000393841.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr11_+_66406088 16.78 ENST00000310092.7
ENST00000396053.4
ENST00000408993.2
RNA binding motif protein 4
chr2_+_187350973 16.77 ENST00000544130.1
zinc finger CCCH-type containing 15
chr9_+_2622085 16.72 ENST00000382099.2
very low density lipoprotein receptor
chr1_-_6259641 16.65 ENST00000234875.4
ribosomal protein L22
chr6_+_64281906 16.60 ENST00000370651.3
protein tyrosine phosphatase type IVA, member 1
chr16_+_447209 16.58 ENST00000382940.4
ENST00000219479.2
NME/NM23 nucleoside diphosphate kinase 4
chr7_-_105925558 16.48 ENST00000222553.3
nicotinamide phosphoribosyltransferase
chr11_+_6625046 16.24 ENST00000396751.2
integrin-linked kinase
chr10_+_26986582 16.20 ENST00000376215.5
ENST00000376203.5
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr22_+_42017280 15.96 ENST00000402580.3
ENST00000428575.2
ENST00000359308.4
X-ray repair complementing defective repair in Chinese hamster cells 6
chr17_-_882966 15.49 ENST00000336868.3
nucleoredoxin
chr1_+_214776516 15.42 ENST00000366955.3
centromere protein F, 350/400kDa
chr1_-_246729544 15.40 ENST00000544618.1
ENST00000366514.4
transcription factor B2, mitochondrial
chr17_-_73179046 15.33 ENST00000314523.7
ENST00000420826.2
small ubiquitin-like modifier 2
chr5_+_134094461 15.19 ENST00000452510.2
ENST00000354283.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr6_-_153304148 15.11 ENST00000229758.3
F-box protein 5
chr6_-_160210604 15.08 ENST00000420894.2
ENST00000539756.1
ENST00000544255.1
t-complex 1
chr10_-_16859361 14.95 ENST00000377921.3
Ras suppressor protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ARNT

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
29.6 148.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
25.5 153.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
21.5 86.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
21.1 84.6 GO:0046452 dihydrofolate metabolic process(GO:0046452)
20.9 146.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
19.9 99.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
19.9 99.6 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
16.5 99.1 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
12.5 25.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
12.0 47.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
11.0 22.0 GO:1990144 intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
11.0 33.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
10.7 224.4 GO:0031639 plasminogen activation(GO:0031639)
10.3 41.2 GO:1901165 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of trophoblast cell migration(GO:1901165)
10.2 152.9 GO:0006089 lactate metabolic process(GO:0006089)
9.9 29.7 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
9.5 37.9 GO:0090402 oncogene-induced cell senescence(GO:0090402)
9.2 46.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
9.1 54.8 GO:0006177 GMP biosynthetic process(GO:0006177)
8.8 52.5 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
8.4 25.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
8.0 48.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
8.0 95.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
7.8 39.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
7.8 46.6 GO:0048254 snoRNA localization(GO:0048254)
7.7 23.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
7.7 23.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
7.7 23.1 GO:0006059 hexitol metabolic process(GO:0006059)
7.7 38.4 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
7.6 22.8 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
7.5 37.7 GO:0015862 uridine transport(GO:0015862)
7.3 58.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
7.3 22.0 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
7.3 36.5 GO:0061198 fungiform papilla formation(GO:0061198)
7.1 21.2 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
7.1 56.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
6.8 20.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
6.5 71.5 GO:0006621 protein retention in ER lumen(GO:0006621)
6.4 12.9 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
6.2 24.9 GO:0002840 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
6.2 24.8 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
6.2 117.0 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
5.9 17.8 GO:0061073 ciliary body morphogenesis(GO:0061073)
5.9 17.8 GO:1990868 beta selection(GO:0043366) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
5.8 17.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
5.4 32.7 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
5.4 21.6 GO:0031860 telomeric 3' overhang formation(GO:0031860)
5.3 101.1 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
5.2 15.6 GO:0021592 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
5.0 49.5 GO:0007000 nucleolus organization(GO:0007000)
4.9 19.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
4.9 24.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
4.9 14.7 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
4.8 19.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
4.7 33.2 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
4.7 85.1 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
4.6 23.0 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
4.6 22.9 GO:0019348 dolichol metabolic process(GO:0019348)
4.5 31.4 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
4.4 17.8 GO:0009956 radial pattern formation(GO:0009956)
4.3 38.9 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
4.2 20.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via threonine(GO:0018243)
4.1 28.6 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
4.1 20.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
4.0 28.0 GO:0033484 nitric oxide homeostasis(GO:0033484)
4.0 11.9 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
3.8 15.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
3.8 11.4 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
3.8 22.6 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
3.7 18.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
3.6 29.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
3.5 10.5 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
3.4 10.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
3.2 12.8 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
3.1 56.6 GO:0042473 outer ear morphogenesis(GO:0042473)
3.1 21.7 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
3.1 27.9 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
3.1 21.6 GO:0070141 response to UV-A(GO:0070141)
3.1 43.0 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
3.1 18.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
3.0 12.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
2.9 28.8 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
2.9 11.5 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
2.8 31.3 GO:0006183 GTP biosynthetic process(GO:0006183)
2.8 14.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
2.8 28.0 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
2.8 8.3 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
2.8 60.9 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
2.7 30.1 GO:0035721 intraciliary retrograde transport(GO:0035721) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
2.7 18.7 GO:0000710 meiotic mismatch repair(GO:0000710)
2.7 8.0 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
2.6 29.1 GO:0045176 apical protein localization(GO:0045176)
2.6 5.3 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
2.6 18.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
2.6 36.0 GO:2000774 positive regulation of cellular senescence(GO:2000774)
2.5 32.9 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
2.5 7.5 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
2.5 12.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
2.5 37.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
2.3 20.3 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
2.2 22.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
2.2 69.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
2.1 12.3 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.9 7.7 GO:2000035 regulation of stem cell division(GO:2000035)
1.9 11.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
1.8 5.5 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
1.8 17.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
1.7 6.9 GO:1902462 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.7 51.2 GO:0032288 myelin assembly(GO:0032288)
1.7 138.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.6 19.2 GO:0001711 endodermal cell fate commitment(GO:0001711)
1.6 9.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
1.6 15.8 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
1.6 4.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.5 24.6 GO:0006107 oxaloacetate metabolic process(GO:0006107)
1.5 21.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
1.5 6.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.5 16.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
1.5 28.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
1.4 12.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.4 15.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
1.3 18.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.3 5.1 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
1.3 17.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.2 6.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.2 22.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.2 30.7 GO:0000002 mitochondrial genome maintenance(GO:0000002)
1.2 15.9 GO:0040016 embryonic cleavage(GO:0040016)
1.2 4.9 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
1.2 15.4 GO:0051382 kinetochore assembly(GO:0051382)
1.2 3.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.2 5.8 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
1.1 12.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.1 16.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
1.1 102.5 GO:0002181 cytoplasmic translation(GO:0002181)
1.1 6.5 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
1.1 9.7 GO:0006552 leucine catabolic process(GO:0006552)
1.0 46.6 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
1.0 15.7 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
1.0 2.9 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
1.0 35.9 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
1.0 3.9 GO:0035026 leading edge cell differentiation(GO:0035026)
0.9 6.5 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.9 3.5 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.9 8.7 GO:0033327 Leydig cell differentiation(GO:0033327)
0.9 4.4 GO:0060356 leucine import(GO:0060356)
0.9 77.5 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.9 14.5 GO:0050872 white fat cell differentiation(GO:0050872)
0.8 5.9 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.8 7.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.8 12.6 GO:0009086 methionine biosynthetic process(GO:0009086)
0.8 3.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.8 8.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.8 6.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.8 19.4 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.7 16.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.7 60.8 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.7 12.1 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.7 2.7 GO:0042360 vitamin E metabolic process(GO:0042360)
0.7 4.7 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.7 3.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.6 5.8 GO:0030656 regulation of vitamin metabolic process(GO:0030656)
0.6 41.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.6 12.4 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.6 5.5 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.6 28.9 GO:0031529 ruffle organization(GO:0031529)
0.6 17.4 GO:0009303 rRNA transcription(GO:0009303)
0.6 30.8 GO:0035904 aorta development(GO:0035904)
0.6 18.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.5 51.9 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.5 37.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.5 3.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.5 2.0 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.5 7.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.5 2.5 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.5 21.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.5 34.1 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.5 1.4 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.5 1.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.5 80.8 GO:0002576 platelet degranulation(GO:0002576)
0.4 12.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 6.6 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.4 12.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.4 9.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.4 17.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.4 7.9 GO:0030252 growth hormone secretion(GO:0030252)
0.4 5.9 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.4 5.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.4 26.9 GO:0006364 rRNA processing(GO:0006364)
0.3 6.4 GO:0017145 stem cell division(GO:0017145)
0.3 2.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.3 3.5 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.3 0.9 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.3 57.5 GO:0008360 regulation of cell shape(GO:0008360)
0.3 16.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.3 10.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.3 1.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 19.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 2.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2 1.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 3.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 2.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.2 6.5 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.2 16.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.2 11.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 2.1 GO:0045008 depyrimidination(GO:0045008)
0.2 0.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 5.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 6.9 GO:0006270 DNA replication initiation(GO:0006270)
0.2 10.4 GO:0006611 protein export from nucleus(GO:0006611)
0.2 0.9 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 5.2 GO:0050900 leukocyte migration(GO:0050900)
0.2 1.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.2 5.9 GO:0032456 endocytic recycling(GO:0032456)
0.2 8.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 28.1 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.9 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.3 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1 9.1 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 5.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 5.8 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 3.8 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 5.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 1.3 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 3.1 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 5.0 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 0.4 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 4.6 GO:0008283 cell proliferation(GO:0008283)
0.1 4.4 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 0.9 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 5.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.5 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 1.6 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 2.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 2.9 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 32.7 GO:0045087 innate immune response(GO:0045087)
0.0 3.5 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 4.3 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
20.7 124.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
16.6 99.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
9.7 48.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
9.3 167.5 GO:0034709 methylosome(GO:0034709)
9.2 46.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
9.0 117.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
8.5 25.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
8.2 24.5 GO:0005960 glycine cleavage complex(GO:0005960)
7.2 28.8 GO:0070985 TFIIK complex(GO:0070985)
6.8 40.9 GO:0070545 PeBoW complex(GO:0070545)
6.3 31.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
5.6 39.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
5.3 63.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
4.8 19.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
4.7 14.2 GO:0044393 microspike(GO:0044393)
4.7 18.7 GO:0032301 MutSalpha complex(GO:0032301)
4.4 84.4 GO:0036020 endolysosome membrane(GO:0036020)
4.4 44.2 GO:0030126 COPI vesicle coat(GO:0030126)
4.3 106.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
4.2 8.3 GO:0030689 Noc complex(GO:0030689)
3.9 23.6 GO:0008537 proteasome activator complex(GO:0008537)
3.9 97.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
3.9 23.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
3.9 170.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
3.4 37.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
3.3 46.4 GO:0070578 RISC-loading complex(GO:0070578)
3.2 22.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
3.1 15.6 GO:0097513 myosin II filament(GO:0097513)
3.1 21.6 GO:0030870 Mre11 complex(GO:0030870)
3.0 56.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
2.9 20.3 GO:0097452 GAIT complex(GO:0097452)
2.9 74.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
2.8 52.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
2.6 15.8 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
2.6 21.0 GO:0070761 pre-snoRNP complex(GO:0070761)
2.6 12.8 GO:0042643 actomyosin, actin portion(GO:0042643)
2.5 30.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
2.4 55.4 GO:0032156 septin cytoskeleton(GO:0032156)
2.3 18.5 GO:0070552 BRISC complex(GO:0070552)
2.2 31.4 GO:0031616 spindle pole centrosome(GO:0031616)
2.1 30.1 GO:0090543 Flemming body(GO:0090543)
2.1 66.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
2.0 32.6 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.9 9.7 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
1.9 19.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.9 9.6 GO:0034457 Mpp10 complex(GO:0034457)
1.9 13.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
1.8 14.5 GO:0097470 ribbon synapse(GO:0097470)
1.8 33.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
1.7 20.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
1.6 64.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.6 17.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
1.5 27.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.4 5.5 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
1.3 9.2 GO:0016272 prefoldin complex(GO:0016272)
1.3 62.5 GO:1904115 axon cytoplasm(GO:1904115)
1.3 5.1 GO:0036449 microtubule minus-end(GO:0036449)
1.2 33.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
1.2 25.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.1 38.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.1 102.6 GO:0043195 terminal bouton(GO:0043195)
1.1 6.6 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
1.1 14.4 GO:0031088 platelet dense granule membrane(GO:0031088)
1.1 16.5 GO:0005686 U2 snRNP(GO:0005686)
1.1 11.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.0 19.9 GO:0042599 lamellar body(GO:0042599)
1.0 12.2 GO:0042575 DNA polymerase complex(GO:0042575)
1.0 8.0 GO:0034719 SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
1.0 49.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.0 64.5 GO:0005637 nuclear inner membrane(GO:0005637)
1.0 17.3 GO:0005685 U1 snRNP(GO:0005685)
1.0 8.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.9 4.7 GO:0070826 paraferritin complex(GO:0070826)
0.9 93.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.9 12.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.8 24.8 GO:0000421 autophagosome membrane(GO:0000421)
0.8 14.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.7 135.4 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.7 30.1 GO:0097542 ciliary tip(GO:0097542)
0.6 119.7 GO:0043209 myelin sheath(GO:0043209)
0.6 71.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.5 16.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.5 4.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.5 39.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.5 19.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 10.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4 24.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4 6.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.4 2.4 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.4 12.6 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.4 36.6 GO:0005643 nuclear pore(GO:0005643)
0.4 5.0 GO:0031528 microvillus membrane(GO:0031528)
0.4 57.6 GO:0016324 apical plasma membrane(GO:0016324)
0.4 6.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 14.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.3 3.8 GO:0030686 90S preribosome(GO:0030686)
0.3 43.6 GO:0016605 PML body(GO:0016605)
0.3 119.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.3 52.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 34.6 GO:0005604 basement membrane(GO:0005604)
0.3 4.4 GO:0001891 phagocytic cup(GO:0001891)
0.3 12.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 5.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.3 2.1 GO:0031931 TORC1 complex(GO:0031931)
0.3 10.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.3 10.9 GO:0030175 filopodium(GO:0030175)
0.3 10.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 5.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.2 5.9 GO:0035869 ciliary transition zone(GO:0035869)
0.2 23.1 GO:0031514 motile cilium(GO:0031514)
0.2 1.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 6.6 GO:0005581 collagen trimer(GO:0005581)
0.2 4.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 174.4 GO:0005730 nucleolus(GO:0005730)
0.2 506.1 GO:0070062 extracellular exosome(GO:0070062)
0.2 3.9 GO:0002102 podosome(GO:0002102)
0.2 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 2.0 GO:0031082 BLOC complex(GO:0031082)
0.2 5.9 GO:0045177 apical part of cell(GO:0045177)
0.1 10.6 GO:0005840 ribosome(GO:0005840)
0.1 7.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 3.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 5.3 GO:0043204 perikaryon(GO:0043204)
0.1 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0030054 cell junction(GO:0030054)
0.0 2.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
74.8 224.4 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
39.0 117.0 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
25.9 155.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
24.8 99.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
21.3 63.9 GO:0033149 FFAT motif binding(GO:0033149)
20.7 124.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
18.5 148.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
17.0 68.0 GO:0005046 KDEL sequence binding(GO:0005046)
16.9 118.4 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
16.2 97.4 GO:0019238 cyclohydrolase activity(GO:0019238)
13.7 41.2 GO:0030984 kininogen binding(GO:0030984)
13.7 54.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
11.0 33.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
9.7 48.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
9.3 37.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
8.5 76.5 GO:0070883 pre-miRNA binding(GO:0070883)
7.7 23.2 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
7.6 22.9 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
7.1 35.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
6.6 32.9 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
6.5 25.9 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
6.4 19.2 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
6.1 24.5 GO:0004047 aminomethyltransferase activity(GO:0004047)
5.8 17.4 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
5.6 22.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
5.5 16.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
5.4 32.7 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
5.1 20.3 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
4.8 48.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
4.7 18.7 GO:0032143 single thymine insertion binding(GO:0032143)
4.5 13.4 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
4.2 16.7 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
4.2 24.9 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
3.9 11.8 GO:0032557 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) pyrimidine ribonucleotide binding(GO:0032557) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
3.8 23.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
3.8 84.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
3.8 22.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
3.7 44.3 GO:0031386 protein tag(GO:0031386)
3.7 22.0 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
3.7 18.3 GO:0004312 fatty acid synthase activity(GO:0004312)
3.6 14.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
3.6 39.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
3.6 21.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
3.5 31.8 GO:0043426 MRF binding(GO:0043426)
3.5 31.3 GO:1901612 cardiolipin binding(GO:1901612)
3.4 23.6 GO:0061133 endopeptidase activator activity(GO:0061133)
3.3 19.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
3.2 35.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
3.1 46.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
3.1 15.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
3.1 126.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
3.1 15.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
3.0 142.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
3.0 48.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
3.0 66.6 GO:0042609 CD4 receptor binding(GO:0042609)
2.9 40.0 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
2.8 22.8 GO:0016842 amidine-lyase activity(GO:0016842)
2.8 79.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
2.8 19.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
2.7 124.6 GO:0003785 actin monomer binding(GO:0003785)
2.7 37.7 GO:0008097 5S rRNA binding(GO:0008097)
2.6 18.5 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
2.6 36.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
2.5 17.7 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
2.5 7.5 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
2.5 17.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
2.5 12.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
2.4 46.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
2.3 18.5 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
2.3 119.9 GO:0016831 carboxy-lyase activity(GO:0016831)
2.3 18.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
2.3 11.4 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
2.2 18.0 GO:0035613 RNA stem-loop binding(GO:0035613)
2.2 67.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
2.1 6.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
2.1 14.5 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
2.0 6.0 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
2.0 7.9 GO:0051920 peroxiredoxin activity(GO:0051920)
2.0 17.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
2.0 43.2 GO:0004707 MAP kinase activity(GO:0004707)
1.9 9.7 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
1.9 5.8 GO:0015235 cobalamin transporter activity(GO:0015235)
1.9 15.4 GO:0070840 dynein complex binding(GO:0070840)
1.9 21.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.9 26.3 GO:0042043 neurexin family protein binding(GO:0042043)
1.8 37.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
1.8 17.7 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.8 10.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.7 27.9 GO:0008494 translation activator activity(GO:0008494)
1.7 12.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.6 21.1 GO:0004985 opioid receptor activity(GO:0004985)
1.6 28.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
1.6 75.3 GO:0051879 Hsp90 protein binding(GO:0051879)
1.6 4.7 GO:0008859 exoribonuclease II activity(GO:0008859)
1.6 21.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
1.5 94.9 GO:0005507 copper ion binding(GO:0005507)
1.4 22.4 GO:0004526 ribonuclease P activity(GO:0004526)
1.4 20.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.4 11.1 GO:0008172 S-methyltransferase activity(GO:0008172)
1.3 11.9 GO:0008312 7S RNA binding(GO:0008312)
1.3 60.3 GO:0019894 kinesin binding(GO:0019894)
1.3 10.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
1.3 22.8 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
1.2 21.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
1.2 12.3 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
1.2 49.0 GO:0004407 histone deacetylase activity(GO:0004407)
1.2 63.8 GO:0051287 NAD binding(GO:0051287)
1.2 2.3 GO:0032357 oxidized purine DNA binding(GO:0032357)
1.1 25.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
1.1 20.3 GO:0043495 protein anchor(GO:0043495)
1.1 12.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
1.1 32.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.1 22.5 GO:0000339 RNA cap binding(GO:0000339)
1.1 43.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.9 21.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.9 5.6 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.9 4.7 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.9 179.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.9 2.7 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.8 15.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.8 39.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.8 3.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.8 20.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.8 13.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.8 17.3 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.7 23.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.7 19.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.7 15.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.7 3.5 GO:0046923 ER retention sequence binding(GO:0046923)
0.7 4.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.7 6.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.7 2.0 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.7 20.4 GO:0005123 death receptor binding(GO:0005123)
0.6 11.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.6 29.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.6 6.5 GO:0046790 virion binding(GO:0046790)
0.6 13.6 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.6 5.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.5 10.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 5.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.5 7.6 GO:0030276 clathrin binding(GO:0030276)
0.5 7.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.5 15.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 17.8 GO:0001972 retinoic acid binding(GO:0001972)
0.4 5.4 GO:0048156 tau protein binding(GO:0048156)
0.4 77.8 GO:0005178 integrin binding(GO:0005178)
0.4 4.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.4 2.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.4 1.6 GO:0004461 lactose synthase activity(GO:0004461)
0.4 22.0 GO:0051087 chaperone binding(GO:0051087)
0.4 6.4 GO:0005112 Notch binding(GO:0005112)
0.4 31.5 GO:0051082 unfolded protein binding(GO:0051082)
0.4 22.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.4 1.4 GO:0097001 ceramide binding(GO:0097001)
0.4 6.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.4 6.4 GO:0035497 cAMP response element binding(GO:0035497)
0.3 9.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.3 0.9 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.3 12.4 GO:0031491 nucleosome binding(GO:0031491)
0.3 5.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 5.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 3.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 2.2 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.2 19.4 GO:0032947 protein complex scaffold(GO:0032947)
0.2 3.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 21.6 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.2 6.4 GO:0017091 AU-rich element binding(GO:0017091)
0.2 3.6 GO:0019213 deacetylase activity(GO:0019213)
0.2 10.9 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 278.3 GO:0003723 RNA binding(GO:0003723)
0.2 4.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 3.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 1.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 3.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 8.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 1.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 3.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 10.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 7.9 GO:0051015 actin filament binding(GO:0051015)
0.1 5.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 3.8 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 109.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
5.4 644.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
4.4 105.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
3.2 246.8 PID ILK PATHWAY Integrin-linked kinase signaling
1.9 63.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
1.8 198.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
1.8 25.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.7 95.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.7 48.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
1.3 63.8 PID PLK1 PATHWAY PLK1 signaling events
1.1 74.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
1.1 28.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.0 13.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.8 26.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.8 15.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.6 18.8 PID RHOA PATHWAY RhoA signaling pathway
0.5 11.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.5 21.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.5 91.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.5 22.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.5 22.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.4 24.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.4 16.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4 18.3 PID AP1 PATHWAY AP-1 transcription factor network
0.3 9.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.3 15.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.3 17.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 10.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.3 15.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.3 68.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 12.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 5.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 16.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 14.7 PID SHP2 PATHWAY SHP2 signaling
0.2 5.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 12.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 6.5 PID IL1 PATHWAY IL1-mediated signaling events
0.2 3.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 13.9 PID CMYB PATHWAY C-MYB transcription factor network
0.2 14.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 3.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 4.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
9.9 168.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
7.6 389.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
5.5 22.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
5.4 5.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
5.1 92.7 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
3.8 84.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
3.7 117.0 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
3.5 87.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
3.0 102.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
2.8 78.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
2.8 47.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
2.3 143.4 REACTOME G1 PHASE Genes involved in G1 Phase
2.3 38.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
2.2 61.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
2.1 41.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
2.0 52.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
2.0 100.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
2.0 88.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
1.9 20.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
1.8 57.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.8 51.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
1.7 58.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.6 47.8 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.6 56.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
1.5 136.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.5 57.3 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
1.3 11.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.2 24.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.2 36.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
1.1 19.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.1 69.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.1 81.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
1.0 9.2 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.0 3.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.9 6.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.9 41.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.9 21.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.9 7.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.8 26.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.8 150.8 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.8 20.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.7 5.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.7 53.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.6 10.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.6 10.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.6 5.5 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.6 6.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.6 10.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.5 17.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.5 6.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.5 19.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.5 20.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.5 12.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 41.9 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.4 16.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.4 6.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.4 11.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.4 9.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.4 9.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 18.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3 5.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.3 1.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 16.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 7.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 17.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 24.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 12.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 20.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 1.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 1.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 2.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 5.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.5 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.4 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.7 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors