averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
AR | hg19_v2_chrX_+_66764375_66764465 | 0.38 | 4.7e-09 | Click! |
NR3C2 | hg19_v2_chr4_-_149365827_149365870 | 0.36 | 3.7e-08 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
14.7 | 117.4 | GO:0036018 | cellular response to erythropoietin(GO:0036018) |
3.9 | 97.7 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
11.3 | 67.6 | GO:0010732 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
0.5 | 66.8 | GO:0030449 | regulation of complement activation(GO:0030449) |
2.9 | 47.0 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
0.1 | 37.9 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
2.3 | 34.9 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
0.1 | 31.9 | GO:0001558 | regulation of cell growth(GO:0001558) |
2.2 | 26.6 | GO:0048251 | elastic fiber assembly(GO:0048251) |
0.0 | 13.4 | GO:0007420 | brain development(GO:0007420) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 295.6 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
13.5 | 67.7 | GO:0005602 | complement component C1 complex(GO:0005602) |
3.4 | 67.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
4.8 | 38.4 | GO:0016012 | sarcoglycan complex(GO:0016012) |
2.7 | 26.6 | GO:0071953 | elastic fiber(GO:0071953) |
0.0 | 21.5 | GO:0016607 | nuclear speck(GO:0016607) |
0.5 | 12.7 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
3.2 | 9.7 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
1.0 | 7.3 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
0.1 | 6.6 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 155.0 | GO:0008270 | zinc ion binding(GO:0008270) |
5.4 | 70.5 | GO:0046870 | cadmium ion binding(GO:0046870) |
0.2 | 68.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
1.3 | 67.6 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.4 | 34.9 | GO:0017022 | myosin binding(GO:0017022) |
0.3 | 12.7 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.1 | 10.9 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
3.2 | 9.7 | GO:0005148 | prolactin receptor binding(GO:0005148) |
0.0 | 9.3 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.0 | 9.3 | GO:0005509 | calcium ion binding(GO:0005509) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 73.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.5 | 70.5 | PID AP1 PATHWAY | AP-1 transcription factor network |
0.4 | 47.0 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
0.1 | 26.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 15.9 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
0.4 | 12.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
0.1 | 8.5 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.1 | 6.5 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.2 | 4.9 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
0.1 | 4.7 | PID IL1 PATHWAY | IL1-mediated signaling events |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 70.5 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
6.2 | 67.7 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.4 | 12.7 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
0.6 | 9.7 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.1 | 7.3 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
0.1 | 4.7 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
0.1 | 2.9 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
0.1 | 2.9 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.1 | 2.7 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
0.1 | 2.6 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |