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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ATF2_ATF1_ATF3

Z-value: 2.26

Motif logo

Transcription factors associated with ATF2_ATF1_ATF3

Gene Symbol Gene ID Gene Info
ENSG00000115966.12 activating transcription factor 2
ENSG00000123268.4 activating transcription factor 1
ENSG00000162772.12 activating transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF2hg19_v2_chr2_-_176032843_1760329410.334.5e-07Click!
ATF3hg19_v2_chr1_+_212738676_212738755,
hg19_v2_chr1_+_212782012_212782257
-0.092.0e-01Click!

Activity profile of ATF2_ATF1_ATF3 motif

Sorted Z-values of ATF2_ATF1_ATF3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_48432892 67.55 ENST00000376759.3
ENST00000430348.2
RNA binding motif (RNP1, RRM) protein 3
chr19_+_1941117 50.92 ENST00000255641.8
casein kinase 1, gamma 2
chr4_+_113558272 49.17 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr8_-_17104356 47.85 ENST00000361272.4
ENST00000523917.1
CCR4-NOT transcription complex, subunit 7
chr6_+_139456226 46.23 ENST00000367658.2
headcase homolog (Drosophila)
chrX_+_155110956 42.97 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
vesicle-associated membrane protein 7
chr12_-_92539614 42.54 ENST00000256015.3
B-cell translocation gene 1, anti-proliferative
chr3_+_38206975 38.69 ENST00000446845.1
ENST00000311806.3
oxidative stress responsive 1
chr3_-_185655795 38.24 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
transformer 2 beta homolog (Drosophila)
chr17_-_685559 38.15 ENST00000301329.6
glyoxalase domain containing 4
chr19_+_50180317 37.83 ENST00000534465.1
protein arginine methyltransferase 1
chr1_+_26496362 35.97 ENST00000374266.5
ENST00000270812.5
zinc finger protein 593
chr12_+_108079664 35.73 ENST00000541166.1
PWP1 homolog (S. cerevisiae)
chr22_-_39096661 35.67 ENST00000216039.5
Josephin domain containing 1
chr17_+_27071002 35.57 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TNF receptor-associated factor 4
chr17_-_685493 35.23 ENST00000536578.1
ENST00000301328.5
ENST00000576419.1
glyoxalase domain containing 4
chr19_-_55919087 34.03 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
ubiquitin-conjugating enzyme E2S
chr6_-_32812420 33.82 ENST00000374881.2
proteasome (prosome, macropain) subunit, beta type, 8
chr2_-_62115725 33.47 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
chaperonin containing TCP1, subunit 4 (delta)
chr2_-_62115659 31.97 ENST00000544185.1
chaperonin containing TCP1, subunit 4 (delta)
chr3_-_10028366 31.80 ENST00000429759.1
ER membrane protein complex subunit 3
chr7_-_25164969 31.77 ENST00000305786.2
cytochrome c, somatic
chr6_-_53213780 31.05 ENST00000304434.6
ENST00000370918.4
ELOVL fatty acid elongase 5
chr18_+_57567180 30.39 ENST00000316660.6
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr19_+_36036477 30.30 ENST00000222284.5
ENST00000392204.2
transmembrane protein 147
chr6_+_47445467 29.53 ENST00000359314.5
CD2-associated protein
chr1_-_115124257 28.97 ENST00000369541.3
breast carcinoma amplified sequence 2
chr19_-_40336969 28.93 ENST00000599134.1
ENST00000597634.1
ENST00000598417.1
ENST00000601274.1
ENST00000594309.1
ENST00000221801.3
fibrillarin
chr14_+_105219437 28.77 ENST00000329967.6
ENST00000347067.5
ENST00000553810.1
SIVA1, apoptosis-inducing factor
chr19_+_36036583 28.47 ENST00000392205.1
transmembrane protein 147
chr14_-_55369525 28.44 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GTP cyclohydrolase 1
chr4_+_113558612 28.36 ENST00000505034.1
ENST00000324052.6
La ribonucleoprotein domain family, member 7
chr5_+_32531893 28.13 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr22_-_36924944 27.97 ENST00000405442.1
ENST00000402116.1
eukaryotic translation initiation factor 3, subunit D
chr5_-_133304473 27.83 ENST00000231512.3
chromosome 5 open reading frame 15
chr19_-_47616992 27.63 ENST00000253048.5
zinc finger CCCH-type containing 4
chr4_-_122744998 27.57 ENST00000274026.5
cyclin A2
chr3_-_156877997 27.19 ENST00000295926.3
cyclin L1
chr16_+_30087288 27.12 ENST00000279387.7
ENST00000562664.1
ENST00000562222.1
protein phosphatase 4, catalytic subunit
chr19_+_24009879 26.29 ENST00000354585.4
ribosomal protein SA pseudogene 58
chr1_-_229644034 26.15 ENST00000366678.3
ENST00000261396.3
ENST00000537506.1
nucleoporin 133kDa
chr16_+_31044413 25.96 ENST00000394998.1
syntaxin 4
chr2_+_113403434 25.96 ENST00000272542.3
solute carrier family 20 (phosphate transporter), member 1
chr9_+_70856899 25.85 ENST00000377342.5
ENST00000478048.1
COBW domain containing 3
chr7_+_56019486 25.60 ENST00000446692.1
ENST00000285298.4
ENST00000443449.1
glioblastoma amplified sequence
mitochondrial ribosomal protein S17
chr11_-_6633799 25.47 ENST00000299424.4
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr17_-_47785504 25.40 ENST00000514907.1
ENST00000503334.1
ENST00000508520.1
solute carrier family 35, member B1
chr9_-_179018 25.28 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
COBW domain containing 1
chr9_-_69262509 25.14 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
COBW domain containing 6
chr5_+_44809027 25.09 ENST00000507110.1
mitochondrial ribosomal protein S30
chr12_-_112856623 24.85 ENST00000551291.2
ribosomal protein L6
chr8_+_98788003 24.29 ENST00000521545.2
lysosomal protein transmembrane 4 beta
chr7_-_86849883 23.97 ENST00000433078.1
transmembrane protein 243, mitochondrial
chr8_-_117778494 23.94 ENST00000276682.4
eukaryotic translation initiation factor 3, subunit H
chr14_+_102276209 23.85 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
protein phosphatase 2, regulatory subunit B', gamma
chr7_+_107531580 23.77 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
dihydrolipoamide dehydrogenase
chr12_+_69979446 23.46 ENST00000543146.2
chaperonin containing TCP1, subunit 2 (beta)
chr14_+_93651358 23.34 ENST00000415050.2
transmembrane protein 251
chr15_+_66797627 23.25 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr12_+_69979210 23.22 ENST00000544368.2
chaperonin containing TCP1, subunit 2 (beta)
chr2_-_240964716 23.17 ENST00000404554.1
ENST00000407129.3
ENST00000307300.4
ENST00000443626.1
ENST00000252711.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr17_+_56769924 23.15 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51 paralog C
chr1_-_19536744 22.97 ENST00000375267.2
ENST00000375217.2
ENST00000375226.2
ENST00000375254.3
ubiquitin protein ligase E3 component n-recognin 4
chr17_-_80231300 22.88 ENST00000398519.5
ENST00000580446.1
casein kinase 1, delta
chr12_+_51632638 22.85 ENST00000549732.2
DAZ associated protein 2
chr19_+_1065922 22.74 ENST00000539243.2
histocompatibility (minor) HA-1
chr6_+_32812568 22.72 ENST00000414474.1
proteasome (prosome, macropain) subunit, beta type, 9
chr2_+_114195268 22.69 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
COBW domain containing 2
chr15_+_66797455 22.62 ENST00000446801.2
zwilch kinetochore protein
chr8_+_26149007 22.57 ENST00000380737.3
ENST00000524169.1
protein phosphatase 2, regulatory subunit B, alpha
chr11_-_3818932 22.14 ENST00000324932.7
ENST00000359171.4
nucleoporin 98kDa
chr12_+_72148614 22.12 ENST00000261263.3
RAB21, member RAS oncogene family
chr7_-_26240357 21.92 ENST00000354667.4
ENST00000356674.7
heterogeneous nuclear ribonucleoprotein A2/B1
chr11_-_3818688 21.86 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
nucleoporin 98kDa
chr12_+_69979113 21.78 ENST00000299300.6
chaperonin containing TCP1, subunit 2 (beta)
chr7_+_127228399 21.76 ENST00000000233.5
ENST00000415666.1
ADP-ribosylation factor 5
chr15_-_66790146 21.63 ENST00000316634.5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr5_+_133707252 21.54 ENST00000506787.1
ENST00000507277.1
ubiquitin-conjugating enzyme E2B
chr10_-_97416400 21.47 ENST00000371224.2
ENST00000371221.3
aldehyde dehydrogenase 18 family, member A1
chr14_+_50359773 21.37 ENST00000298316.5
ADP-ribosylation factor 6
chr1_-_110950564 21.19 ENST00000256644.4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr15_+_52311398 20.84 ENST00000261845.5
mitogen-activated protein kinase 6
chr3_+_140660743 20.81 ENST00000453248.2
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr11_+_18416103 20.63 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
lactate dehydrogenase A
chr11_+_4116054 20.62 ENST00000423050.2
ribonucleotide reductase M1
chr8_+_42196000 20.58 ENST00000518925.1
ENST00000538005.1
polymerase (DNA directed), beta
chr4_-_104119528 20.53 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr1_-_32110467 20.44 ENST00000440872.2
ENST00000373703.4
penta-EF-hand domain containing 1
chr7_-_23571586 20.41 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
transformer 2 alpha homolog (Drosophila)
chrX_-_47518498 20.38 ENST00000335890.2
ubiquitously-expressed, prefoldin-like chaperone
chr9_+_70856397 20.37 ENST00000360171.6
COBW domain containing 3
chr8_+_42195972 20.26 ENST00000532157.1
ENST00000265421.4
ENST00000520008.1
polymerase (DNA directed), beta
chr16_-_81040719 20.13 ENST00000219400.3
C-x(9)-C motif containing 2
chr6_-_31774714 20.11 ENST00000375661.5
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_-_68290106 20.11 ENST00000407324.1
ENST00000355848.3
ENST00000409302.1
ENST00000410067.3
C1D nuclear receptor corepressor
chr1_-_53704157 20.09 ENST00000371466.4
ENST00000371470.3
mago-nashi homolog, proliferation-associated (Drosophila)
chr3_-_49066811 20.04 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr14_+_93651296 20.04 ENST00000283534.4
ENST00000557574.1
transmembrane protein 251
Uncharacterized protein
chr14_-_50053081 19.90 ENST00000396020.3
ENST00000245458.6
ribosomal protein S29
chr17_+_7476136 19.82 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr8_-_103876383 19.74 ENST00000347770.4
antizyme inhibitor 1
chr4_-_76598544 19.65 ENST00000515457.1
ENST00000357854.3
GTPase activating protein (SH3 domain) binding protein 2
chr1_+_52082751 19.64 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
oxysterol binding protein-like 9
chr11_+_4116005 19.64 ENST00000300738.5
ribonucleotide reductase M1
chr22_-_36925186 19.61 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
eukaryotic translation initiation factor 3, subunit D
chr3_-_49142178 19.60 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
glutaminyl-tRNA synthetase
chr17_+_7155556 19.60 ENST00000570500.1
ENST00000574993.1
ENST00000396628.2
ENST00000573657.1
elongator acetyltransferase complex subunit 5
chr19_+_50180409 19.59 ENST00000391851.4
protein arginine methyltransferase 1
chr20_-_48729670 19.55 ENST00000371657.5
ubiquitin-conjugating enzyme E2 variant 1
chr19_-_59066327 19.55 ENST00000596708.1
ENST00000601220.1
ENST00000597848.1
charged multivesicular body protein 2A
chr14_+_55518349 19.52 ENST00000395468.4
mitogen-activated protein kinase 1 interacting protein 1-like
chr19_-_8070474 19.47 ENST00000407627.2
ENST00000593807.1
ELAV like RNA binding protein 1
chr11_+_118230287 19.14 ENST00000252108.3
ENST00000431736.2
ubiquitination factor E4A
chr5_-_133561752 19.13 ENST00000519718.1
ENST00000481195.1
S-phase kinase-associated protein 1
protein phosphatase 2, catalytic subunit, alpha isozyme
chr6_-_43027105 19.10 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr7_+_116660246 19.03 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
suppression of tumorigenicity 7
chr5_-_10761206 18.95 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr12_-_102455846 18.95 ENST00000545679.1
coiled-coil domain containing 53
chr8_+_126442563 18.75 ENST00000311922.3
tribbles pseudokinase 1
chr17_+_15902694 18.48 ENST00000261647.5
ENST00000486880.2
tetratricopeptide repeat domain 19
chr11_-_64546202 18.44 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
splicing factor 1
chr12_-_14956396 18.31 ENST00000535328.1
ENST00000261167.2
WW domain binding protein 11
chr12_+_56521840 18.26 ENST00000394048.5
extended synaptotagmin-like protein 1
chr17_-_8113542 18.24 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr12_+_98987369 18.20 ENST00000401722.3
ENST00000188376.5
ENST00000228318.3
ENST00000551917.1
ENST00000548046.1
ENST00000552981.1
ENST00000551265.1
ENST00000550695.1
ENST00000547534.1
ENST00000549338.1
ENST00000548847.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr8_-_101964231 18.18 ENST00000521309.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr7_+_120591170 18.11 ENST00000431467.1
inhibitor of growth family, member 3
chr9_-_70490107 18.10 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
COBW domain containing 5
chr5_+_5422778 18.08 ENST00000296564.7
KIAA0947
chr7_-_137686791 17.99 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
cAMP responsive element binding protein 3-like 2
chr17_-_47785265 17.91 ENST00000511763.1
ENST00000515850.1
ENST00000415270.2
ENST00000240333.6
solute carrier family 35, member B1
chrX_-_47518527 17.81 ENST00000333119.3
ubiquitously-expressed, prefoldin-like chaperone
chr14_+_60715928 17.74 ENST00000395076.4
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr12_-_102455902 17.68 ENST00000240079.6
coiled-coil domain containing 53
chr11_+_18416133 17.65 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
lactate dehydrogenase A
chr1_-_159894319 17.65 ENST00000320307.4
transgelin 2
chr1_+_45205478 17.53 ENST00000452259.1
ENST00000372224.4
kinesin family member 2C
chr21_-_40720995 17.38 ENST00000380749.5
high mobility group nucleosome binding domain 1
chr7_+_26240776 17.28 ENST00000337620.4
chromobox homolog 3
chr17_+_685513 17.18 ENST00000304478.4
RNA methyltransferase like 1
chr10_+_35484793 17.04 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr20_-_48732472 17.03 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
ubiquitin-conjugating enzyme E2 variant 1
chr6_+_64281906 16.96 ENST00000370651.3
protein tyrosine phosphatase type IVA, member 1
chr8_+_125486939 16.93 ENST00000303545.3
ring finger protein 139
chr19_-_59066452 16.88 ENST00000312547.2
charged multivesicular body protein 2A
chr9_-_111696224 16.82 ENST00000537196.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr17_-_77813186 16.68 ENST00000448310.1
ENST00000269397.4
chromobox homolog 4
chr2_+_187350883 16.67 ENST00000337859.6
zinc finger CCCH-type containing 15
chrX_+_77359671 16.52 ENST00000373316.4
phosphoglycerate kinase 1
chr19_+_16186903 16.47 ENST00000588507.1
tropomyosin 4
chr1_+_45205498 16.37 ENST00000372218.4
kinesin family member 2C
chr19_-_39881777 16.37 ENST00000595564.1
ENST00000221265.3
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr14_+_74353508 16.33 ENST00000324593.6
ENST00000557495.1
ENST00000556659.1
ENST00000557363.1
zinc finger protein 410
chrX_+_77359726 16.24 ENST00000442431.1
phosphoglycerate kinase 1
chr17_-_61850894 16.03 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
coiled-coil domain containing 47
chr8_-_117768023 15.93 ENST00000518949.1
ENST00000522453.1
ENST00000521861.1
ENST00000518995.1
eukaryotic translation initiation factor 3, subunit H
chr19_-_9546227 15.93 ENST00000361451.2
ENST00000361151.1
zinc finger protein 266
chr11_+_65337901 15.91 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
Sjogren syndrome/scleroderma autoantigen 1
chr19_-_18392422 15.91 ENST00000252818.3
jun D proto-oncogene
chr12_-_82752565 15.76 ENST00000256151.7
coiled-coil domain containing 59
chr17_-_47841485 15.69 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A
chr1_-_70671216 15.66 ENST00000370952.3
leucine rich repeat containing 40
chr1_+_228327943 15.57 ENST00000366726.1
ENST00000312726.4
ENST00000366728.2
ENST00000453943.1
ENST00000366723.1
ENST00000366722.1
ENST00000435153.1
ENST00000366721.1
guanylate kinase 1
chr7_+_120590803 15.47 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
inhibitor of growth family, member 3
chr12_+_51632600 15.47 ENST00000549555.1
ENST00000439799.2
ENST00000425012.2
DAZ associated protein 2
chr3_+_180630444 15.47 ENST00000491062.1
ENST00000468861.1
ENST00000445140.2
ENST00000484958.1
fragile X mental retardation, autosomal homolog 1
chr2_+_118572226 15.30 ENST00000263239.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr10_+_13203543 15.29 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
minichromosome maintenance complex component 10
chr19_-_14530143 15.21 ENST00000242776.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chrX_+_153672468 15.19 ENST00000393600.3
family with sequence similarity 50, member A
chr8_-_101964265 15.19 ENST00000395958.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr16_+_3068393 15.12 ENST00000573001.1
tumor necrosis factor receptor superfamily, member 12A
chr5_+_162887556 15.12 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
hyaluronan-mediated motility receptor (RHAMM)
chr8_+_23386557 15.10 ENST00000523930.1
solute carrier family 25 (mitochondrial iron transporter), member 37
chr4_-_54930790 14.92 ENST00000263921.3
cysteine-rich hydrophobic domain 2
chr22_+_24236191 14.87 ENST00000215754.7
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr14_+_74353574 14.85 ENST00000442160.3
ENST00000555044.1
zinc finger protein 410
chr12_+_69633372 14.83 ENST00000456847.3
ENST00000266679.8
cleavage and polyadenylation specific factor 6, 68kDa
chr18_+_20513278 14.60 ENST00000327155.5
retinoblastoma binding protein 8
chr17_+_33914460 14.57 ENST00000537622.2
adaptor-related protein complex 2, beta 1 subunit
chr12_+_51632508 14.52 ENST00000449723.3
DAZ associated protein 2
chr12_+_54378923 14.46 ENST00000303460.4
homeobox C10
chr1_+_228327923 14.46 ENST00000391865.3
guanylate kinase 1
chr22_+_39898325 14.42 ENST00000325301.2
ENST00000404569.1
mitochondrial elongation factor 1
chr17_+_7155819 14.39 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr4_-_84205905 14.30 ENST00000311461.7
ENST00000311469.4
ENST00000439031.2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
chr3_+_180630090 14.30 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chr17_+_33914276 14.19 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr1_-_110950255 14.16 ENST00000483260.1
ENST00000474861.2
ENST00000602318.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr12_+_75874460 14.16 ENST00000266659.3
GLI pathogenesis-related 1
chr12_+_113344755 14.06 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr20_-_48729696 14.04 ENST00000371674.3
ubiquitin-conjugating enzyme E2 variant 1
chr1_+_95616933 14.04 ENST00000604203.1
TMEM56-RWDD3 readthrough
chr16_-_3767506 14.01 ENST00000538171.1
TNF receptor-associated protein 1
chr19_+_49375649 13.98 ENST00000200453.5
protein phosphatase 1, regulatory subunit 15A
chr7_-_45151272 13.93 ENST00000461363.1
ENST00000495078.1
ENST00000494076.1
ENST00000478532.1
ENST00000258770.3
ENST00000361278.3
transforming growth factor beta regulator 4
chr7_+_23221613 13.89 ENST00000410002.3
ENST00000413919.1
nucleoporin like 2
chr1_+_39456895 13.80 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
akirin 1
chr16_+_81040794 13.78 ENST00000439957.3
ENST00000393335.3
ENST00000428963.2
ENST00000564669.1
centromere protein N
chr21_-_44846999 13.63 ENST00000270162.6
salt-inducible kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF2_ATF1_ATF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
22.8 68.5 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
16.1 48.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
15.9 47.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
14.4 43.3 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
14.3 43.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
13.6 40.8 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
12.9 38.7 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
12.1 36.4 GO:1903722 regulation of centriole elongation(GO:1903722)
12.0 12.0 GO:0043103 hypoxanthine salvage(GO:0043103)
11.6 69.7 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
11.3 34.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
10.6 31.7 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
10.0 30.0 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
9.9 29.7 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
9.8 29.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
9.6 38.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
9.5 28.5 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
9.3 65.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
9.0 27.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
9.0 26.9 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
8.9 26.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
8.8 44.0 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
8.3 58.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
7.9 7.9 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
7.8 23.5 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
7.2 28.9 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
7.1 28.4 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
6.9 27.6 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
6.6 26.5 GO:0009386 translational attenuation(GO:0009386)
6.5 26.1 GO:0051664 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
6.5 6.5 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
6.5 19.5 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
6.4 25.5 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
6.2 18.7 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
6.0 18.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
5.7 28.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
5.4 16.1 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
5.2 31.5 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
5.2 41.7 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
5.2 20.7 GO:0009106 lipoate metabolic process(GO:0009106)
5.0 14.9 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
4.9 19.8 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
4.9 19.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
4.8 14.5 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
4.8 29.0 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
4.7 14.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
4.7 14.0 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
4.6 22.8 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
4.6 72.8 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
4.5 13.5 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
4.5 17.9 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
4.4 21.9 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
4.1 28.9 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
4.1 28.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
3.9 55.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
3.8 11.5 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
3.8 7.7 GO:0002188 translation reinitiation(GO:0002188)
3.7 18.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
3.6 10.8 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
3.6 21.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
3.4 20.6 GO:0006499 N-terminal protein myristoylation(GO:0006499)
3.4 6.8 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
3.4 23.6 GO:1902416 positive regulation of mRNA binding(GO:1902416)
3.3 20.0 GO:0006177 GMP biosynthetic process(GO:0006177)
3.3 13.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
3.3 23.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
3.1 40.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
3.1 37.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
3.1 21.5 GO:0033484 nitric oxide homeostasis(GO:0033484)
3.1 30.7 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
3.0 27.4 GO:0016584 nucleosome positioning(GO:0016584)
3.0 8.9 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
2.9 26.5 GO:0007042 lysosomal lumen acidification(GO:0007042)
2.9 17.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
2.9 8.6 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
2.8 16.9 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
2.8 16.9 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
2.8 8.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
2.8 5.6 GO:0007500 mesodermal cell fate determination(GO:0007500)
2.7 27.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
2.7 27.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
2.7 8.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
2.7 13.5 GO:0048388 endosomal lumen acidification(GO:0048388)
2.7 26.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
2.7 47.7 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
2.7 8.0 GO:0006624 vacuolar protein processing(GO:0006624)
2.6 15.7 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) histone H3-T11 phosphorylation(GO:0035407)
2.6 10.5 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
2.6 34.0 GO:0006089 lactate metabolic process(GO:0006089)
2.5 5.1 GO:0002572 pro-T cell differentiation(GO:0002572)
2.4 12.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
2.4 40.3 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
2.4 7.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
2.4 21.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
2.3 18.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.3 7.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
2.3 9.2 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
2.3 2.3 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
2.3 6.8 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
2.3 33.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
2.2 33.4 GO:0090168 Golgi reassembly(GO:0090168)
2.2 8.9 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
2.2 22.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
2.2 4.4 GO:0001922 B-1 B cell homeostasis(GO:0001922)
2.2 8.7 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
2.2 19.5 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
2.1 8.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
2.1 2.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
2.1 6.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
2.1 8.5 GO:0043335 protein unfolding(GO:0043335)
2.1 4.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
2.1 16.9 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
2.1 12.6 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
2.1 8.4 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.0 36.9 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
2.0 32.8 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
2.0 32.5 GO:0045116 protein neddylation(GO:0045116)
2.0 16.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.0 20.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
2.0 5.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
1.9 9.7 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
1.9 1.9 GO:1901857 positive regulation of cellular respiration(GO:1901857)
1.9 7.7 GO:0044027 hypermethylation of CpG island(GO:0044027)
1.9 25.0 GO:0070365 hepatocyte differentiation(GO:0070365)
1.9 9.6 GO:0019348 dolichol metabolic process(GO:0019348)
1.9 28.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
1.9 41.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
1.8 14.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
1.8 19.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.8 10.6 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
1.8 5.3 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
1.8 8.8 GO:0048539 bone marrow development(GO:0048539)
1.7 12.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
1.7 5.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
1.7 84.0 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
1.7 12.0 GO:0035562 negative regulation of chromatin binding(GO:0035562)
1.7 13.4 GO:0015693 magnesium ion transport(GO:0015693)
1.7 6.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
1.7 11.7 GO:0032202 telomere assembly(GO:0032202)
1.7 6.6 GO:0072719 cellular response to cisplatin(GO:0072719)
1.7 29.8 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
1.6 8.2 GO:0060356 leucine import(GO:0060356)
1.6 9.9 GO:0051025 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.6 27.8 GO:0006265 DNA topological change(GO:0006265)
1.6 9.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
1.6 12.9 GO:1902570 protein localization to nucleolus(GO:1902570)
1.6 8.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
1.6 11.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
1.6 6.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.6 14.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
1.6 1.6 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
1.6 4.7 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.6 12.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
1.5 10.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
1.5 9.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
1.5 6.1 GO:2000035 regulation of stem cell division(GO:2000035)
1.5 9.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.5 4.5 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
1.5 4.5 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
1.5 5.9 GO:1903288 positive regulation of potassium ion import(GO:1903288)
1.5 28.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.5 61.3 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
1.4 7.2 GO:0080009 mRNA methylation(GO:0080009)
1.4 2.9 GO:0010628 positive regulation of gene expression(GO:0010628)
1.4 5.7 GO:0090135 actin filament branching(GO:0090135)
1.4 7.1 GO:0006449 regulation of translational termination(GO:0006449)
1.4 27.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
1.4 7.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
1.4 2.8 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
1.3 9.4 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
1.3 1.3 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
1.3 21.4 GO:0036010 protein localization to endosome(GO:0036010)
1.3 5.3 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
1.3 4.0 GO:2000641 regulation of early endosome to late endosome transport(GO:2000641)
1.3 7.9 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.3 10.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.3 4.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.3 7.9 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
1.3 11.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.3 5.2 GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.3 37.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
1.3 91.3 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
1.2 37.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
1.2 8.7 GO:2000252 negative regulation of feeding behavior(GO:2000252)
1.2 33.6 GO:0043968 histone H2A acetylation(GO:0043968)
1.2 33.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.2 4.9 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
1.2 102.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
1.2 29.8 GO:0031639 plasminogen activation(GO:0031639)
1.2 2.4 GO:0006788 heme oxidation(GO:0006788)
1.2 7.1 GO:0015853 adenine transport(GO:0015853)
1.2 7.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.2 4.7 GO:0003164 His-Purkinje system development(GO:0003164)
1.2 4.7 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
1.2 8.1 GO:0089700 protein kinase D signaling(GO:0089700)
1.2 11.6 GO:0015939 pantothenate metabolic process(GO:0015939)
1.2 1.2 GO:0051604 protein maturation(GO:0051604)
1.1 4.6 GO:0030242 pexophagy(GO:0030242)
1.1 6.8 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
1.1 26.2 GO:0006376 mRNA splice site selection(GO:0006376)
1.1 9.0 GO:0051660 establishment of centrosome localization(GO:0051660)
1.1 3.4 GO:1903224 regulation of endodermal cell differentiation(GO:1903224) negative regulation of gastrulation(GO:2000542)
1.1 29.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
1.1 12.2 GO:1902969 mitotic DNA replication(GO:1902969)
1.1 4.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
1.1 19.6 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
1.1 4.3 GO:0042418 epinephrine biosynthetic process(GO:0042418)
1.1 3.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.0 6.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.0 19.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
1.0 3.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
1.0 9.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.0 1.0 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
1.0 4.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.0 14.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.0 4.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.0 10.8 GO:0090400 stress-induced premature senescence(GO:0090400)
1.0 77.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.0 2.9 GO:0060278 negative regulation of B cell differentiation(GO:0045578) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.0 1.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
1.0 15.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.9 35.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.9 1.9 GO:0048818 positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795)
0.9 9.4 GO:0010225 response to UV-C(GO:0010225)
0.9 8.3 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.9 5.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.9 3.6 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.9 8.2 GO:0044827 modulation by host of viral genome replication(GO:0044827) positive regulation by host of viral genome replication(GO:0044829)
0.9 2.7 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.9 6.3 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.9 3.6 GO:0030307 positive regulation of cell growth(GO:0030307)
0.9 2.7 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.9 8.0 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.9 8.0 GO:0032264 IMP salvage(GO:0032264)
0.9 6.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.9 9.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.9 9.4 GO:0033227 dsRNA transport(GO:0033227)
0.8 28.0 GO:0031648 protein destabilization(GO:0031648)
0.8 3.4 GO:0046967 cytosol to ER transport(GO:0046967)
0.8 5.9 GO:0000012 single strand break repair(GO:0000012)
0.8 7.5 GO:1904424 regulation of GTP binding(GO:1904424)
0.8 13.8 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.8 52.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.8 25.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.8 1.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.8 16.6 GO:0061157 mRNA destabilization(GO:0061157)
0.8 4.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.8 17.9 GO:0016579 protein deubiquitination(GO:0016579)
0.8 4.6 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.8 8.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.8 7.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.8 20.4 GO:0006378 mRNA polyadenylation(GO:0006378)
0.7 3.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.7 20.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.7 29.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.7 9.5 GO:0019388 galactose catabolic process(GO:0019388)
0.7 10.2 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.7 5.8 GO:0010265 SCF complex assembly(GO:0010265)
0.7 2.9 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.7 2.9 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.7 3.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.7 4.3 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.7 15.7 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.7 6.4 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.7 7.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.7 1.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.7 1.4 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.7 3.5 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.7 4.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.7 0.7 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.7 70.7 GO:0045727 positive regulation of translation(GO:0045727)
0.7 7.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.7 3.3 GO:0002027 regulation of heart rate(GO:0002027)
0.7 7.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.7 2.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.7 14.6 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.7 2.0 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.7 2.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.6 5.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.6 7.6 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.6 1.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.6 3.8 GO:1904044 response to aldosterone(GO:1904044)
0.6 3.7 GO:0042254 ribosome biogenesis(GO:0042254)
0.6 0.6 GO:0036480 neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.6 1.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.6 2.4 GO:0048496 maintenance of organ identity(GO:0048496)
0.6 6.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.6 9.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.6 1.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.6 10.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.6 4.6 GO:1904872 RNA localization to Cajal body(GO:0090670) telomerase RNA localization to Cajal body(GO:0090671) telomerase RNA localization(GO:0090672) regulation of telomerase RNA localization to Cajal body(GO:1904872)
0.6 3.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.5 6.6 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.5 14.2 GO:0006270 DNA replication initiation(GO:0006270)
0.5 7.6 GO:0031053 primary miRNA processing(GO:0031053)
0.5 3.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.5 27.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.5 2.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.5 4.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.5 1.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.5 5.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.5 2.1 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.5 3.2 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.5 5.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.5 19.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.5 3.6 GO:0006116 NADH oxidation(GO:0006116)
0.5 6.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.5 29.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.5 3.6 GO:0070933 histone H4 deacetylation(GO:0070933)
0.5 2.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.5 24.9 GO:0006110 regulation of glycolytic process(GO:0006110)
0.5 2.5 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.5 1.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.5 50.8 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.5 6.4 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.5 4.4 GO:0030099 myeloid cell differentiation(GO:0030099)
0.5 1.9 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.5 10.1 GO:0044764 multi-organism cellular process(GO:0044764)
0.5 4.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.5 1.9 GO:0030035 microspike assembly(GO:0030035)
0.5 12.9 GO:0002076 osteoblast development(GO:0002076)
0.5 2.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.5 6.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.5 9.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.5 0.5 GO:0002874 chronic inflammatory response to antigenic stimulus(GO:0002439) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.5 3.7 GO:0006689 ganglioside catabolic process(GO:0006689)
0.5 2.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) regulation of t-circle formation(GO:1904429) positive regulation of t-circle formation(GO:1904431)
0.5 6.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.5 8.2 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.5 5.0 GO:0006105 succinate metabolic process(GO:0006105)
0.4 8.0 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.4 2.6 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4 8.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.4 1.7 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.4 2.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.4 2.1 GO:0035063 nuclear speck organization(GO:0035063)
0.4 7.7 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.4 1.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.4 6.0 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.4 1.3 GO:0042351 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.4 5.9 GO:0051014 actin filament severing(GO:0051014)
0.4 81.7 GO:0006413 translational initiation(GO:0006413)
0.4 3.4 GO:0001878 response to yeast(GO:0001878)
0.4 6.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.4 3.6 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.4 1.6 GO:0006642 triglyceride mobilization(GO:0006642)
0.4 3.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.4 10.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.4 3.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.4 76.4 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.4 14.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.4 1.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.4 94.0 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.4 1.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.4 4.2 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.4 1.9 GO:0016045 detection of bacterium(GO:0016045)
0.4 8.0 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.4 3.3 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.4 37.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.3 1.0 GO:0061743 motor learning(GO:0061743)
0.3 4.1 GO:0001782 B cell homeostasis(GO:0001782)
0.3 2.7 GO:0051601 exocyst localization(GO:0051601)
0.3 1.7 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.3 2.3 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 1.3 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.3 0.3 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.3 0.7 GO:1904502 lipophagy(GO:0061724) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.3 1.3 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3 2.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.3 14.3 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.3 3.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.3 2.5 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.3 5.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3 2.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 4.9 GO:0016578 histone deubiquitination(GO:0016578)
0.3 1.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.3 6.7 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.3 17.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.3 3.8 GO:0019985 translesion synthesis(GO:0019985)
0.3 1.7 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.3 2.0 GO:0018065 protein-cofactor linkage(GO:0018065)
0.3 1.1 GO:0048743 regulation of skeletal muscle fiber development(GO:0048742) positive regulation of skeletal muscle fiber development(GO:0048743)
0.3 6.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.3 1.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.3 0.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 6.6 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.3 0.8 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.3 12.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.3 1.6 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.3 5.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 16.9 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.3 3.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.3 6.2 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.3 0.8 GO:0090656 t-circle formation(GO:0090656)
0.3 0.5 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.2 20.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.2 1.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 8.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 0.5 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.2 8.2 GO:0002576 platelet degranulation(GO:0002576)
0.2 2.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 1.9 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.2 2.3 GO:0035855 megakaryocyte development(GO:0035855)
0.2 10.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.2 1.8 GO:0051028 mRNA transport(GO:0051028)
0.2 1.8 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.2 2.9 GO:0009595 detection of biotic stimulus(GO:0009595)
0.2 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 2.0 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.2 3.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 1.1 GO:0051924 regulation of calcium ion transport(GO:0051924)
0.2 2.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.2 1.4 GO:0034629 cellular protein complex localization(GO:0034629)
0.2 1.8 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 0.6 GO:1903795 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) regulation of inorganic anion transmembrane transport(GO:1903795) positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.2 10.7 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 0.8 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.2 1.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) negative regulation of dendritic spine maintenance(GO:1902951)
0.2 0.9 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 1.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 7.2 GO:0061621 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 1.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.2 1.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 9.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 1.0 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.2 0.9 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 4.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.2 0.5 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.2 1.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.2 3.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 6.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 2.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 2.7 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 2.6 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.6 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) primary lung bud formation(GO:0060431) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.1 1.2 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.7 GO:2001214 blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842) positive regulation of vasculogenesis(GO:2001214)
0.1 2.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 4.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.8 GO:0006953 acute-phase response(GO:0006953)
0.1 0.9 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 10.4 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 7.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 3.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 3.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 2.2 GO:1901186 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.1 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.9 GO:0070995 NADPH oxidation(GO:0070995)
0.1 1.0 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 2.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.3 GO:0042659 regulation of cell fate specification(GO:0042659)
0.1 10.3 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.1 0.5 GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.7 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 3.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 3.7 GO:0007032 endosome organization(GO:0007032)
0.1 0.4 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.1 9.6 GO:0046718 viral entry into host cell(GO:0046718)
0.1 1.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 2.4 GO:0042554 superoxide anion generation(GO:0042554)
0.1 2.8 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1 1.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.3 GO:0070253 somatostatin secretion(GO:0070253)
0.1 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 1.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.8 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.8 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 2.3 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.7 GO:0002021 response to dietary excess(GO:0002021)
0.1 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.5 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 3.8 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.1 2.0 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.3 GO:0055093 response to hyperoxia(GO:0055093)
0.1 1.8 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.9 GO:0007567 parturition(GO:0007567)
0.1 0.9 GO:0030728 ovulation(GO:0030728)
0.1 0.3 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 1.0 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.6 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.8 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 1.0 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:0006907 pinocytosis(GO:0006907)
0.0 0.7 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 1.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.7 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0032278 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 1.3 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 2.8 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.5 GO:0001889 liver development(GO:0001889) hepaticobiliary system development(GO:0061008)
0.0 4.1 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 0.2 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.2 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.6 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
12.3 61.3 GO:0035370 UBC13-UEV1A complex(GO:0035370)
12.0 47.9 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
11.4 45.7 GO:1990423 RZZ complex(GO:1990423)
11.3 33.9 GO:0097447 dendritic tree(GO:0097447)
10.8 32.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
10.1 131.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
10.1 40.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
9.7 87.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
9.6 28.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
9.0 27.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
8.7 69.6 GO:1990111 spermatoproteasome complex(GO:1990111)
7.7 30.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
7.7 46.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
7.1 28.4 GO:0005846 nuclear cap binding complex(GO:0005846)
7.1 35.4 GO:0071986 Ragulator complex(GO:0071986)
6.9 20.7 GO:0005873 plus-end kinesin complex(GO:0005873)
6.6 59.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
6.6 19.7 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
5.5 98.7 GO:0034709 methylosome(GO:0034709)
5.4 26.9 GO:0033503 HULC complex(GO:0033503)
5.2 41.8 GO:0000322 storage vacuole(GO:0000322)
5.0 15.1 GO:0043159 acrosomal matrix(GO:0043159)
5.0 59.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
4.7 18.8 GO:0000799 nuclear condensin complex(GO:0000799)
4.6 13.7 GO:1902636 kinociliary basal body(GO:1902636)
4.5 13.5 GO:0070557 PCNA-p21 complex(GO:0070557)
4.0 16.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
3.7 76.8 GO:0071011 precatalytic spliceosome(GO:0071011)
3.6 32.8 GO:0072546 ER membrane protein complex(GO:0072546)
3.6 10.8 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
3.6 28.5 GO:0070552 BRISC complex(GO:0070552)
3.5 13.9 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
3.4 27.1 GO:0032133 chromosome passenger complex(GO:0032133)
3.4 16.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
3.4 10.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
3.1 63.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
3.1 12.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
3.0 15.0 GO:0005663 DNA replication factor C complex(GO:0005663)
2.8 96.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
2.8 25.5 GO:0000125 PCAF complex(GO:0000125)
2.8 8.5 GO:0001741 XY body(GO:0001741)
2.8 22.4 GO:0042382 paraspeckles(GO:0042382)
2.8 35.8 GO:0000815 ESCRT III complex(GO:0000815)
2.7 19.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
2.7 8.2 GO:0030689 Noc complex(GO:0030689)
2.6 7.7 GO:0071159 NF-kappaB complex(GO:0071159)
2.5 48.0 GO:0036020 endolysosome membrane(GO:0036020)
2.5 20.0 GO:0031298 replication fork protection complex(GO:0031298)
2.4 19.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
2.4 14.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
2.3 32.9 GO:0090543 Flemming body(GO:0090543)
2.3 4.7 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
2.2 35.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
2.2 6.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
2.1 17.1 GO:0035976 AP1 complex(GO:0035976)
2.1 10.3 GO:0044530 supraspliceosomal complex(GO:0044530)
2.0 20.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.9 11.7 GO:0008537 proteasome activator complex(GO:0008537)
1.9 21.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
1.9 11.5 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.9 7.6 GO:0044611 nuclear pore inner ring(GO:0044611)
1.8 55.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.8 38.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.8 20.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.8 16.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.8 3.6 GO:0030870 Mre11 complex(GO:0030870)
1.8 5.4 GO:0031523 Myb complex(GO:0031523)
1.6 17.9 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
1.6 6.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
1.6 16.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
1.6 14.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
1.6 44.1 GO:0031143 pseudopodium(GO:0031143)
1.6 9.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
1.5 5.8 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
1.4 78.0 GO:0005876 spindle microtubule(GO:0005876)
1.4 17.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.4 7.1 GO:0071817 MMXD complex(GO:0071817)
1.4 34.6 GO:0035371 microtubule plus-end(GO:0035371)
1.4 15.2 GO:0070765 gamma-secretase complex(GO:0070765)
1.4 31.5 GO:0032156 septin cytoskeleton(GO:0032156)
1.3 39.1 GO:0005680 anaphase-promoting complex(GO:0005680)
1.3 28.1 GO:0000930 gamma-tubulin complex(GO:0000930)
1.3 9.4 GO:0016589 NURF complex(GO:0016589)
1.3 50.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
1.3 17.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.3 13.2 GO:0044292 dendrite terminus(GO:0044292)
1.2 34.9 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
1.2 26.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.2 3.6 GO:0001652 granular component(GO:0001652)
1.2 62.8 GO:0031941 filamentous actin(GO:0031941)
1.2 174.0 GO:0015934 large ribosomal subunit(GO:0015934)
1.2 3.5 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
1.1 26.2 GO:0030127 COPII vesicle coat(GO:0030127)
1.1 7.9 GO:0016461 unconventional myosin complex(GO:0016461)
1.1 3.4 GO:0005588 collagen type V trimer(GO:0005588)
1.1 11.1 GO:0070187 telosome(GO:0070187)
1.1 3.3 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
1.1 8.8 GO:0034719 SMN-Sm protein complex(GO:0034719)
1.1 12.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.1 3.2 GO:0033565 ESCRT-0 complex(GO:0033565)
1.0 9.4 GO:0030126 COPI vesicle coat(GO:0030126)
1.0 16.4 GO:0000178 exosome (RNase complex)(GO:0000178)
1.0 11.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.0 7.0 GO:0031415 NatA complex(GO:0031415)
1.0 64.2 GO:0035577 azurophil granule membrane(GO:0035577)
1.0 2.9 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.9 9.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.9 9.9 GO:0005869 dynactin complex(GO:0005869)
0.9 7.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.9 12.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.8 165.2 GO:0005681 spliceosomal complex(GO:0005681)
0.8 4.9 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.8 4.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.8 3.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.8 4.9 GO:0000124 SAGA complex(GO:0000124)
0.8 4.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.8 12.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.8 7.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.8 8.6 GO:0030137 COPI-coated vesicle(GO:0030137)
0.8 4.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.7 13.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.7 44.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.7 7.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.7 30.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.7 34.4 GO:0043034 costamere(GO:0043034)
0.7 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.7 11.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.7 3.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.7 9.3 GO:0035102 PRC1 complex(GO:0035102)
0.7 2.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.6 4.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.6 7.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.6 30.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.6 3.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.6 4.9 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.6 11.5 GO:0097225 sperm midpiece(GO:0097225)
0.6 62.5 GO:0005840 ribosome(GO:0005840)
0.6 1.8 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.6 14.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.6 9.3 GO:0030686 90S preribosome(GO:0030686)
0.6 4.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.6 15.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.6 6.8 GO:1990909 Wnt signalosome(GO:1990909)
0.6 3.4 GO:0042825 TAP complex(GO:0042825)
0.6 63.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.6 2.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.6 3.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.6 6.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.5 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.5 4.7 GO:0061574 ASAP complex(GO:0061574)
0.5 1.0 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.5 3.5 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.5 13.6 GO:0035861 site of double-strand break(GO:0035861)
0.5 2.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.5 13.0 GO:0098553 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.5 41.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.5 5.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.4 9.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.4 48.3 GO:0016605 PML body(GO:0016605)
0.4 28.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.4 2.1 GO:0034464 BBSome(GO:0034464)
0.4 27.0 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.4 32.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.4 30.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.4 2.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.4 4.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.4 3.3 GO:0032059 bleb(GO:0032059)
0.4 4.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 6.6 GO:0042734 presynaptic membrane(GO:0042734)
0.3 4.9 GO:0071437 invadopodium(GO:0071437)
0.3 8.0 GO:0016234 inclusion body(GO:0016234)
0.3 3.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.3 7.9 GO:0032420 stereocilium(GO:0032420)
0.3 8.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 1.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 24.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 4.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.3 10.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 8.9 GO:0072686 mitotic spindle(GO:0072686)
0.3 28.0 GO:0000781 chromosome, telomeric region(GO:0000781)
0.3 10.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.3 25.5 GO:0005643 nuclear pore(GO:0005643)
0.3 1.7 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.3 6.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 3.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 1.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3 4.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 3.1 GO:0044327 dendritic spine head(GO:0044327)
0.2 2.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 0.9 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.2 0.7 GO:0030904 retromer complex(GO:0030904)
0.2 12.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.2 17.5 GO:0031902 late endosome membrane(GO:0031902)
0.2 61.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 0.8 GO:0033263 CORVET complex(GO:0033263)
0.2 1.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 0.9 GO:0042587 glycogen granule(GO:0042587)
0.2 14.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 2.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 15.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 1.4 GO:0031970 organelle envelope lumen(GO:0031970)
0.2 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 6.8 GO:0000502 proteasome complex(GO:0000502)
0.2 0.7 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 7.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 14.1 GO:0034399 nuclear periphery(GO:0034399)
0.1 7.0 GO:0005635 nuclear envelope(GO:0005635)
0.1 4.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.0 GO:0043196 varicosity(GO:0043196)
0.1 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 2.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 5.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 33.8 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.1 0.8 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 1.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.4 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 22.1 GO:0005769 early endosome(GO:0005769)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 1.2 GO:0005740 mitochondrial envelope(GO:0005740)
0.1 1.4 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 6.4 GO:0005903 brush border(GO:0005903)
0.1 4.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 8.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 4.5 GO:0005814 centriole(GO:0005814)
0.1 13.1 GO:0031965 nuclear membrane(GO:0031965)
0.1 2.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.8 GO:0042383 sarcolemma(GO:0042383)
0.0 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 19.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.8 GO:0000791 euchromatin(GO:0000791) nuclear euchromatin(GO:0005719)
0.0 2.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 2.6 GO:0005819 spindle(GO:0005819)
0.0 0.8 GO:0005795 Golgi stack(GO:0005795)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0043235 receptor complex(GO:0043235)
0.0 5.3 GO:0016607 nuclear speck(GO:0016607)
0.0 1.6 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.4 43.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
13.8 41.4 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
13.6 54.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
12.0 36.0 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
11.6 69.7 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
10.6 31.7 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
10.1 40.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
8.9 26.7 GO:0008859 exoribonuclease II activity(GO:0008859)
8.3 33.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
7.8 23.5 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
7.0 7.0 GO:0032427 GBD domain binding(GO:0032427)
6.5 19.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
6.5 26.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
5.8 76.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
5.7 28.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
5.5 38.3 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
5.2 31.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
5.1 20.5 GO:0043515 kinetochore binding(GO:0043515)
5.0 20.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
4.9 4.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
4.7 28.4 GO:0019238 cyclohydrolase activity(GO:0019238)
4.7 14.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
4.5 13.5 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
4.4 70.0 GO:0031996 thioesterase binding(GO:0031996)
4.4 95.8 GO:0000339 RNA cap binding(GO:0000339)
4.3 12.8 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
4.3 25.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
4.2 12.5 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
4.1 12.3 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
4.1 28.5 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
3.9 27.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
3.5 13.9 GO:0000104 succinate dehydrogenase activity(GO:0000104)
3.4 125.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
3.4 33.7 GO:0019237 centromeric DNA binding(GO:0019237)
3.2 25.5 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
3.2 9.5 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
3.1 63.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
3.1 12.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
3.1 9.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
3.0 27.1 GO:0035174 histone serine kinase activity(GO:0035174)
3.0 33.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
3.0 77.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
2.9 8.7 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
2.9 52.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
2.9 14.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
2.9 23.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
2.8 31.3 GO:0033592 RNA strand annealing activity(GO:0033592)
2.8 8.5 GO:0098770 FBXO family protein binding(GO:0098770)
2.8 16.9 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
2.8 8.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
2.7 13.7 GO:0002046 opsin binding(GO:0002046)
2.7 15.9 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
2.6 15.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.6 77.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
2.6 10.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
2.5 17.7 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
2.5 14.9 GO:0004167 dopachrome isomerase activity(GO:0004167)
2.5 17.3 GO:1990226 histone methyltransferase binding(GO:1990226)
2.5 19.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
2.4 7.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
2.4 14.5 GO:0019776 Atg8 ligase activity(GO:0019776)
2.4 16.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
2.4 40.8 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
2.4 35.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
2.3 51.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
2.3 13.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
2.2 8.9 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
2.2 6.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
2.2 28.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
2.2 6.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
2.1 15.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.1 21.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
2.1 4.2 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.1 31.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
2.1 20.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
2.0 6.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
2.0 19.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
1.9 13.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.9 15.5 GO:0097100 supercoiled DNA binding(GO:0097100)
1.9 7.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.8 18.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
1.8 10.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.8 7.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
1.7 5.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
1.7 10.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
1.7 13.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
1.7 77.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
1.7 11.7 GO:0061133 endopeptidase activator activity(GO:0061133)
1.6 9.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.6 4.9 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
1.6 4.9 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
1.6 70.1 GO:0050699 WW domain binding(GO:0050699)
1.6 8.0 GO:1990460 leptin receptor binding(GO:1990460)
1.6 61.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
1.6 9.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.6 65.6 GO:0036002 pre-mRNA binding(GO:0036002)
1.5 9.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
1.5 15.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.5 25.6 GO:0070513 death domain binding(GO:0070513)
1.5 23.8 GO:0050811 GABA receptor binding(GO:0050811)
1.5 23.5 GO:0097602 cullin family protein binding(GO:0097602)
1.4 88.6 GO:0003743 translation initiation factor activity(GO:0003743)
1.4 7.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.4 19.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
1.4 8.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
1.3 6.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
1.3 2.6 GO:0004998 transferrin receptor activity(GO:0004998)
1.3 6.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
1.3 18.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
1.3 38.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
1.3 1.3 GO:0048039 ubiquinone binding(GO:0048039)
1.2 12.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.2 19.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.2 4.9 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
1.2 8.5 GO:0030911 TPR domain binding(GO:0030911)
1.2 7.3 GO:0071532 ankyrin repeat binding(GO:0071532)
1.2 9.7 GO:0070087 chromo shadow domain binding(GO:0070087)
1.2 20.5 GO:0003688 DNA replication origin binding(GO:0003688)
1.2 4.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.1 19.2 GO:0035497 cAMP response element binding(GO:0035497)
1.1 10.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
1.1 4.4 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
1.1 16.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
1.1 7.7 GO:0051525 NFAT protein binding(GO:0051525)
1.1 6.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.1 32.4 GO:0005540 hyaluronic acid binding(GO:0005540)
1.1 4.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
1.1 18.2 GO:0017160 Ral GTPase binding(GO:0017160)
1.1 21.3 GO:0050321 tau-protein kinase activity(GO:0050321)
1.1 3.2 GO:0051380 beta-adrenergic receptor activity(GO:0004939) norepinephrine binding(GO:0051380)
1.1 68.8 GO:0035064 methylated histone binding(GO:0035064)
1.1 11.6 GO:0008097 5S rRNA binding(GO:0008097)
1.0 8.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.0 5.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
1.0 15.5 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
1.0 3.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.0 3.0 GO:0034046 poly(G) binding(GO:0034046)
1.0 52.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.0 20.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.0 2.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.0 2.9 GO:0070699 type II activin receptor binding(GO:0070699)
1.0 11.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.9 32.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.9 3.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.9 9.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.9 3.7 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.9 12.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.9 2.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.9 36.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.9 8.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.8 3.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.8 2.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.8 11.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.8 8.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.8 54.0 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.8 175.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.8 7.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.8 4.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.8 4.0 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.8 8.0 GO:0045545 syndecan binding(GO:0045545)
0.8 8.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.8 2.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.8 1.6 GO:0030984 kininogen binding(GO:0030984)
0.8 30.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.8 4.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8 6.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.8 21.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.8 14.7 GO:0048156 tau protein binding(GO:0048156)
0.7 2.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.7 29.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.7 5.8 GO:0034594 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.7 5.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.7 12.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.7 7.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.7 4.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.7 30.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.7 12.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.7 2.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.7 8.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.7 25.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.7 28.7 GO:0000049 tRNA binding(GO:0000049)
0.6 9.1 GO:0051787 misfolded protein binding(GO:0051787)
0.6 3.9 GO:0017018 myosin phosphatase activity(GO:0017018)
0.6 1.9 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.6 22.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.6 13.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.6 4.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.6 17.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.6 5.5 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.6 3.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.6 20.5 GO:0015248 sterol transporter activity(GO:0015248)
0.6 7.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.6 3.4 GO:0023029 MHC class Ib protein binding(GO:0023029) TAP2 binding(GO:0046979)
0.6 1.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 5.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.5 1.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.5 2.7 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.5 2.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.5 5.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.5 18.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.5 7.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.5 1.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.5 3.2 GO:0039552 RIG-I binding(GO:0039552)
0.5 4.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.5 6.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.5 8.1 GO:0004697 protein kinase C activity(GO:0004697)
0.5 1.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.5 7.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 3.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 1.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.5 3.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.5 35.0 GO:0032947 protein complex scaffold(GO:0032947)
0.5 5.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.5 1.9 GO:0004966 galanin receptor activity(GO:0004966)
0.5 6.0 GO:0004707 MAP kinase activity(GO:0004707)
0.5 24.2 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.5 7.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.5 17.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.4 7.6 GO:0070402 NADPH binding(GO:0070402)
0.4 5.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4 45.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.4 4.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.4 11.5 GO:0043531 ADP binding(GO:0043531)
0.4 29.8 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.4 4.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.4 3.8 GO:0051400 BH domain binding(GO:0051400)
0.4 6.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.4 3.6 GO:0019534 toxin transporter activity(GO:0019534)
0.4 7.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 4.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 5.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.4 8.9 GO:0070840 dynein complex binding(GO:0070840)
0.4 1.5 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.4 13.5 GO:0019894 kinesin binding(GO:0019894)
0.4 13.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 2.6 GO:0035173 histone kinase activity(GO:0035173)
0.4 22.1 GO:0019003 GDP binding(GO:0019003)
0.4 3.6 GO:0008432 JUN kinase binding(GO:0008432)
0.4 2.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.4 14.8 GO:0003684 damaged DNA binding(GO:0003684)
0.3 4.7 GO:0031491 nucleosome binding(GO:0031491)
0.3 7.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.3 3.4 GO:0008201 heparin binding(GO:0008201)
0.3 17.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.3 51.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.3 3.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 8.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.3 1.0 GO:0070051 fibrinogen binding(GO:0070051)
0.3 3.5 GO:0031386 protein tag(GO:0031386)
0.3 37.1 GO:0044325 ion channel binding(GO:0044325)
0.3 6.9 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 3.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 5.1 GO:0017091 AU-rich element binding(GO:0017091)
0.3 4.0 GO:0050700 CARD domain binding(GO:0050700)
0.3 23.2 GO:0019905 syntaxin binding(GO:0019905)
0.3 9.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 20.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.3 4.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 3.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 1.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.3 4.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 7.8 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.3 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 2.4 GO:0008301 DNA binding, bending(GO:0008301)
0.2 2.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 2.9 GO:0043422 protein kinase B binding(GO:0043422)
0.2 0.9 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 2.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 2.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 3.7 GO:0005521 lamin binding(GO:0005521)
0.2 0.7 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 12.9 GO:0004386 helicase activity(GO:0004386)
0.2 18.9 GO:0051082 unfolded protein binding(GO:0051082)
0.2 5.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 3.4 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.6 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 2.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 2.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.9 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.2 0.9 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 5.7 GO:0005109 frizzled binding(GO:0005109)
0.2 214.0 GO:0003723 RNA binding(GO:0003723)
0.2 2.0 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.2 6.5 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.2 4.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 2.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 2.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 2.4 GO:0045503 dynein light chain binding(GO:0045503)
0.2 8.6 GO:0070888 E-box binding(GO:0070888)
0.2 1.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 3.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 1.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.2 35.9 GO:0045296 cadherin binding(GO:0045296)
0.2 1.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.8 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 1.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.5 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 6.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.9 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.3 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 6.5 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 0.8 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.1 3.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.7 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 2.4 GO:0004872 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.1 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 1.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 3.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 3.8 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 3.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 3.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 2.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 1.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 2.9 PID FAS PATHWAY FAS (CD95) signaling pathway
2.0 82.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
1.8 165.5 PID P53 REGULATION PATHWAY p53 pathway
1.3 80.8 PID AURORA B PATHWAY Aurora B signaling
1.2 127.3 PID E2F PATHWAY E2F transcription factor network
1.0 37.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
1.0 22.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
1.0 121.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
1.0 26.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.9 49.4 PID IL1 PATHWAY IL1-mediated signaling events
0.8 25.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.8 16.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.8 12.5 ST STAT3 PATHWAY STAT3 Pathway
0.7 19.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7 36.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.7 6.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.7 9.5 PID FOXO PATHWAY FoxO family signaling
0.7 8.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.7 18.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.6 12.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.6 23.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.6 18.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.6 34.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.6 13.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.5 16.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.5 14.0 PID IGF1 PATHWAY IGF1 pathway
0.5 22.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.5 11.8 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.5 26.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.5 30.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.5 71.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.5 40.7 PID CMYB PATHWAY C-MYB transcription factor network
0.5 7.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 7.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.4 15.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.4 10.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.4 3.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.4 12.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.4 12.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.3 6.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 3.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.3 4.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 4.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 12.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 4.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 6.6 PID REELIN PATHWAY Reelin signaling pathway
0.2 12.0 PID CDC42 PATHWAY CDC42 signaling events
0.2 1.9 PID ATM PATHWAY ATM pathway
0.2 4.7 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.2 4.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 2.7 PID INSULIN PATHWAY Insulin Pathway
0.2 1.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 4.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 5.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.3 PID AP1 PATHWAY AP-1 transcription factor network
0.1 3.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.3 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 2.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 2.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 130.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
3.2 51.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.8 50.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
2.3 59.8 REACTOME KINESINS Genes involved in Kinesins
2.2 53.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
2.1 70.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.1 72.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
2.1 34.9 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
1.9 53.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
1.9 47.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.9 143.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.9 40.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
1.8 38.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.8 42.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.8 45.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
1.8 36.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
1.8 18.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
1.8 39.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
1.7 15.7 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
1.7 32.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.7 40.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.6 64.2 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
1.6 44.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
1.6 48.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
1.5 118.0 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
1.5 33.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.4 20.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.4 22.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
1.4 46.5 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.4 49.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
1.3 7.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
1.3 8.9 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
1.2 32.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
1.2 38.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.2 19.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.2 46.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
1.2 20.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.1 26.8 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
1.1 28.6 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
1.0 70.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
1.0 9.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.0 36.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.9 23.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.9 4.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.9 28.8 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.9 17.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.9 10.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.9 7.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.9 29.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.9 28.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.9 15.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.9 10.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.9 70.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.8 26.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.8 26.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.8 93.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.8 23.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.8 9.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.7 19.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.7 17.3 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.7 123.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.7 2.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.7 8.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.6 28.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.6 7.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.6 22.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.6 50.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.6 30.1 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.6 29.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.6 22.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.6 4.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.6 35.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.6 3.6 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.6 17.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.6 6.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.6 1.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.5 4.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.5 34.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.5 16.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.5 11.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.5 1.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 6.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.4 39.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.4 4.3 REACTOME OPSINS Genes involved in Opsins
0.4 3.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 5.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.3 20.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 8.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.3 7.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 7.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 10.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 3.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.3 1.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 7.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 2.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 6.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 3.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 11.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 3.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 34.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 7.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 20.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2 1.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 2.0 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 10.1 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.2 1.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 1.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 4.3 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.2 3.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 5.8 REACTOME TRANSLATION Genes involved in Translation
0.1 8.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 2.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.2 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.1 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 4.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 5.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 2.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones