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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for BACH2

Z-value: 1.27

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Transcription factors associated with BACH2

Gene Symbol Gene ID Gene Info
ENSG00000112182.10 BTB domain and CNC homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BACH2hg19_v2_chr6_-_91006627_91006641,
hg19_v2_chr6_-_91006461_91006517
-0.251.4e-04Click!

Activity profile of BACH2 motif

Sorted Z-values of BACH2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_89988259 27.68 ENST00000554444.1
ENST00000556565.1
Tubulin beta-3 chain
chr12_+_7023735 22.05 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
enolase 2 (gamma, neuronal)
chr12_+_7023491 21.86 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chr11_-_64013288 21.53 ENST00000542235.1
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr7_-_96339132 20.98 ENST00000413065.1
split hand/foot malformation (ectrodactyly) type 1
chr9_-_130637244 18.71 ENST00000373156.1
adenylate kinase 1
chr6_-_38670897 18.56 ENST00000373365.4
glyoxalase I
chr2_+_231921574 17.51 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr16_+_30077055 17.34 ENST00000564595.2
ENST00000569798.1
aldolase A, fructose-bisphosphate
chr9_-_127177703 17.03 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
proteasome (prosome, macropain) subunit, beta type, 7
chr9_+_140135665 17.01 ENST00000340384.4
tubulin, beta 4B class IVb
chr17_-_73150629 15.87 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
hematological and neurological expressed 1
chr17_+_35851570 15.84 ENST00000394386.1
dual specificity phosphatase 14
chr3_-_98241358 15.81 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
claudin domain containing 1
chr11_-_64013663 15.69 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_+_223889285 15.66 ENST00000433674.2
calpain 2, (m/II) large subunit
chr17_-_65362678 14.76 ENST00000357146.4
ENST00000356126.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr1_+_36621529 14.61 ENST00000316156.4
MAP7 domain containing 1
chr1_+_26606608 14.25 ENST00000319041.6
SH3 domain binding glutamic acid-rich protein like 3
chr1_+_36621697 14.18 ENST00000373150.4
ENST00000373151.2
MAP7 domain containing 1
chr17_+_79650962 14.09 ENST00000329138.4
hepatocyte growth factor-regulated tyrosine kinase substrate
chr5_+_159436120 13.47 ENST00000522793.1
ENST00000231238.5
tetratricopeptide repeat domain 1
chr1_-_109968973 12.87 ENST00000271308.4
ENST00000538610.1
proteasome (prosome, macropain) subunit, alpha type, 5
chrX_-_15511438 12.44 ENST00000380420.5
pirin (iron-binding nuclear protein)
chr4_-_74088800 12.36 ENST00000509867.2
ankyrin repeat domain 17
chr6_+_44194762 12.35 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr7_-_96339167 12.33 ENST00000444799.1
ENST00000417009.1
ENST00000248566.2
split hand/foot malformation (ectrodactyly) type 1
chr6_+_150070831 12.13 ENST00000367380.5
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr16_+_30077098 12.02 ENST00000395240.3
ENST00000566846.1
aldolase A, fructose-bisphosphate
chr19_+_36630855 11.73 ENST00000589146.1
calpain, small subunit 1
chr5_+_138089100 11.60 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr12_-_76478686 11.58 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr15_+_75335604 11.05 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr6_-_31704282 10.91 ENST00000375784.3
ENST00000375779.2
chloride intracellular channel 1
chr19_+_36630961 10.85 ENST00000587718.1
ENST00000592483.1
ENST00000590874.1
ENST00000588815.1
calpain, small subunit 1
chr6_+_150070857 10.72 ENST00000544496.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr6_+_44214824 10.56 ENST00000371646.5
ENST00000353801.3
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr1_+_26605618 10.56 ENST00000270792.5
SH3 domain binding glutamic acid-rich protein like 3
chr16_+_58533951 10.54 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG family member 4
chr20_+_44034804 10.37 ENST00000357275.2
ENST00000372720.3
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr1_+_156095951 10.23 ENST00000448611.2
ENST00000368297.1
lamin A/C
chr15_+_22892663 10.04 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
cytoplasmic FMR1 interacting protein 1
chr19_+_36630454 9.84 ENST00000246533.3
calpain, small subunit 1
chr6_+_2988847 9.09 ENST00000380472.3
ENST00000605901.1
ENST00000454015.1
NAD(P)H dehydrogenase, quinone 2
long intergenic non-protein coding RNA 1011
chr16_+_74330673 9.02 ENST00000219313.4
ENST00000540379.1
ENST00000567958.1
ENST00000568615.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr11_+_63448918 8.90 ENST00000341307.2
ENST00000356000.3
ENST00000542238.1
reticulon 3
chr12_+_64798095 8.79 ENST00000332707.5
exportin, tRNA
chr11_-_65667997 8.54 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr7_+_99006232 8.45 ENST00000403633.2
BUD31 homolog (S. cerevisiae)
chr13_-_36429763 8.26 ENST00000379893.1
doublecortin-like kinase 1
chr11_-_65667884 8.06 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr12_-_76478417 8.01 ENST00000552342.1
nucleosome assembly protein 1-like 1
chr9_-_32573130 7.95 ENST00000350021.2
ENST00000379847.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr1_-_27816641 7.93 ENST00000430629.2
WAS protein family, member 2
chr3_+_69134080 7.92 ENST00000273258.3
ADP-ribosylation-like factor 6 interacting protein 5
chr12_-_76478386 7.74 ENST00000535020.2
nucleosome assembly protein 1-like 1
chr6_-_35888905 7.69 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr3_-_81792780 7.48 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr10_+_88854926 7.27 ENST00000298784.1
ENST00000298786.4
family with sequence similarity 35, member A
chr7_+_148395959 6.99 ENST00000325222.4
cullin 1
chr17_+_30677136 6.86 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
zinc finger protein 207
chr17_+_30469473 6.79 ENST00000333942.6
ENST00000358365.3
ENST00000583994.1
ENST00000545287.2
ras homolog family member T1
chr16_+_57662419 6.76 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
G protein-coupled receptor 56
chr3_+_69134124 6.68 ENST00000478935.1
ADP-ribosylation-like factor 6 interacting protein 5
chr1_+_156096336 6.63 ENST00000504687.1
ENST00000473598.2
lamin A/C
chr12_-_53343602 6.54 ENST00000546897.1
ENST00000552551.1
keratin 8
chr16_+_22308717 6.37 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr5_-_137911049 6.33 ENST00000297185.3
heat shock 70kDa protein 9 (mortalin)
chr17_+_30469579 6.29 ENST00000354266.3
ENST00000581094.1
ENST00000394692.2
ras homolog family member T1
chr5_-_175843569 6.19 ENST00000310418.4
ENST00000345807.2
clathrin, light chain B
chr16_+_57662138 6.11 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
G protein-coupled receptor 56
chr10_+_85899196 6.10 ENST00000372134.3
growth hormone inducible transmembrane protein
chr14_+_103801140 6.01 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
eukaryotic translation initiation factor 5
chr12_-_76478446 5.54 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
nucleosome assembly protein 1-like 1
chr9_-_114246635 5.50 ENST00000338205.5
KIAA0368
chr5_+_72143988 5.43 ENST00000506351.2
transportin 1
chr6_-_35888824 5.36 ENST00000361690.3
ENST00000512445.1
SRSF protein kinase 1
chr1_+_156084461 5.35 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
lamin A/C
chr11_-_66103867 5.18 ENST00000424433.2
Ras and Rab interactor 1
chr17_+_30771279 5.05 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr8_-_59572301 5.04 ENST00000038176.3
neutral sphingomyelinase (N-SMase) activation associated factor
chr10_-_23003460 4.82 ENST00000376573.4
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr6_-_84140757 4.80 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr11_-_102668879 4.69 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr6_+_44215603 4.66 ENST00000371554.1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr1_+_223900034 4.57 ENST00000295006.5
calpain 2, (m/II) large subunit
chr2_-_85641162 4.50 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
capping protein (actin filament), gelsolin-like
chr11_-_66104237 4.42 ENST00000530056.1
Ras and Rab interactor 1
chr2_-_11484710 4.41 ENST00000315872.6
Rho-associated, coiled-coil containing protein kinase 2
chr17_-_27503770 4.32 ENST00000533112.1
myosin XVIIIA
chr17_-_7590745 4.22 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
tumor protein p53
chr17_+_75315534 4.05 ENST00000590294.1
ENST00000329047.8
septin 9
chr1_+_150480551 3.94 ENST00000369049.4
ENST00000369047.4
extracellular matrix protein 1
chr20_+_34742650 3.89 ENST00000373945.1
ENST00000338074.2
erythrocyte membrane protein band 4.1-like 1
chr10_+_88428206 3.87 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LIM domain binding 3
chr7_+_150065278 3.87 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
replication initiator 1
chr6_-_159239257 3.87 ENST00000337147.7
ENST00000392177.4
ezrin
chr7_-_102985035 3.85 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DnaJ (Hsp40) homolog, subfamily C, member 2
chr17_-_76921459 3.63 ENST00000262768.7
TIMP metallopeptidase inhibitor 2
chr14_-_23426337 3.56 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS augmin-like complex, subunit 4
chr1_-_11918988 3.56 ENST00000376468.3
natriuretic peptide B
chr13_-_67802549 3.54 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr1_-_153521597 3.49 ENST00000368712.1
S100 calcium binding protein A3
chr14_-_23426322 3.48 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr16_+_15596123 3.45 ENST00000452191.2
chromosome 16 open reading frame 45
chr4_-_100356551 3.37 ENST00000209665.4
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_+_55162453 3.25 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
A kinase (PRKA) anchor protein 1
chr14_-_23426270 3.24 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS augmin-like complex, subunit 4
chr19_-_10450287 3.11 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr17_-_18161870 3.00 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
flightless I homolog (Drosophila)
chr18_-_49557 2.99 ENST00000308911.6
Tubulin beta-8 chain-like protein LOC260334
chr1_-_153521714 2.98 ENST00000368713.3
S100 calcium binding protein A3
chr18_+_268148 2.92 ENST00000581677.1
RP11-705O1.8
chr5_-_176923803 2.90 ENST00000506161.1
PDZ and LIM domain 7 (enigma)
chr1_-_6662919 2.89 ENST00000377658.4
ENST00000377663.3
kelch-like family member 21
chr11_-_2924720 2.89 ENST00000455942.2
solute carrier family 22 (organic cation transporter), member 18 antisense
chr11_-_62323702 2.88 ENST00000530285.1
AHNAK nucleoprotein
chr1_-_40157345 2.77 ENST00000372844.3
hippocalcin like 4
chr1_+_155107820 2.76 ENST00000484157.1
solute carrier family 50 (sugar efflux transporter), member 1
chr1_+_150480576 2.75 ENST00000346569.6
extracellular matrix protein 1
chr3_-_11610255 2.71 ENST00000424529.2
vestigial like 4 (Drosophila)
chr5_-_175843524 2.60 ENST00000502877.1
clathrin, light chain B
chr3_-_49395705 2.57 ENST00000419349.1
glutathione peroxidase 1
chr15_-_60690163 2.53 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
annexin A2
chr12_-_7818474 2.52 ENST00000229304.4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr4_-_100356844 2.50 ENST00000437033.2
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr10_+_121410882 2.48 ENST00000369085.3
BCL2-associated athanogene 3
chr1_-_156675368 2.48 ENST00000368222.3
cellular retinoic acid binding protein 2
chr2_+_220144052 2.48 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DnaJ (Hsp40) homolog, subfamily B, member 2
chr6_+_106959718 2.36 ENST00000369066.3
absent in melanoma 1
chr17_+_21191341 2.29 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
mitogen-activated protein kinase kinase 3
chr4_+_170581213 2.21 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr22_+_20861858 2.14 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
mediator complex subunit 15
chr8_+_24771265 2.11 ENST00000518131.1
ENST00000437366.2
neurofilament, medium polypeptide
chr2_+_220143989 2.10 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr17_+_7123125 2.07 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
acyl-CoA dehydrogenase, very long chain
chr14_-_75643296 2.03 ENST00000303575.4
transmembrane emp24-like trafficking protein 10 (yeast)
chr20_+_35807512 2.03 ENST00000373622.5
ribophorin II
chrX_-_129244655 1.98 ENST00000335997.7
E74-like factor 4 (ets domain transcription factor)
chr5_-_176923846 1.87 ENST00000506537.1
PDZ and LIM domain 7 (enigma)
chr15_+_44829255 1.80 ENST00000261868.5
ENST00000424492.3
eukaryotic translation initiation factor 3, subunit J
chr12_-_56122426 1.80 ENST00000551173.1
CD63 molecule
chr1_-_179112173 1.76 ENST00000408940.3
ENST00000504405.1
c-abl oncogene 2, non-receptor tyrosine kinase
chr4_+_74606223 1.75 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr18_+_61442629 1.72 ENST00000398019.2
ENST00000540675.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_+_20620946 1.70 ENST00000525748.1
solute carrier family 6 (neurotransmitter transporter), member 5
chr3_-_49823941 1.69 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
inositol hexakisphosphate kinase 1
chrX_-_129244454 1.58 ENST00000308167.5
E74-like factor 4 (ets domain transcription factor)
chr11_-_102826434 1.57 ENST00000340273.4
ENST00000260302.3
matrix metallopeptidase 13 (collagenase 3)
chr17_-_39538550 1.51 ENST00000394001.1
keratin 34
chr15_+_89182156 1.43 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr11_+_10476851 1.37 ENST00000396553.2
adenosine monophosphate deaminase 3
chr5_+_179247759 1.36 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
sequestosome 1
chr7_-_107643674 1.35 ENST00000222399.6
laminin, beta 1
chr9_-_139922726 1.34 ENST00000265662.5
ENST00000371605.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr11_+_35639735 1.32 ENST00000317811.4
four jointed box 1 (Drosophila)
chr17_-_48785216 1.26 ENST00000285243.6
ankyrin repeat domain 40
chr7_+_116312411 1.21 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chr15_+_89181974 1.19 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr17_-_73775839 1.18 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3 histone, family 3B (H3.3B)
chr6_-_56819385 1.09 ENST00000370754.5
ENST00000449297.2
dystonin
chr12_+_6644443 1.05 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr18_+_32290218 1.00 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
dystrobrevin, alpha
chr15_+_89182178 0.86 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr16_+_67571351 0.79 ENST00000428437.2
ENST00000569253.1
family with sequence similarity 65, member A
chr4_-_146019693 0.78 ENST00000514390.1
anaphase promoting complex subunit 10
chr1_-_151965048 0.78 ENST00000368809.1
S100 calcium binding protein A10
chr21_-_36421626 0.66 ENST00000300305.3
runt-related transcription factor 1
chr1_+_154377669 0.64 ENST00000368485.3
ENST00000344086.4
interleukin 6 receptor
chr4_-_987217 0.49 ENST00000361661.2
ENST00000398516.2
solute carrier family 26 (anion exchanger), member 1
chr7_+_97361388 0.48 ENST00000350485.4
ENST00000346867.4
tachykinin, precursor 1
chr3_-_56502375 0.48 ENST00000288221.6
ELKS/RAB6-interacting/CAST family member 2
chr19_-_55881741 0.48 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
interleukin 11
chr1_+_153003671 0.47 ENST00000307098.4
small proline-rich protein 1B
chr6_-_31745085 0.45 ENST00000375686.3
ENST00000447450.1
von Willebrand factor A domain containing 7
chr19_-_46285646 0.41 ENST00000458663.2
dystrophia myotonica-protein kinase
chr18_-_268019 0.40 ENST00000261600.6
THO complex 1
chr21_-_36421401 0.38 ENST00000486278.2
runt-related transcription factor 1
chr3_+_187930719 0.36 ENST00000312675.4
LIM domain containing preferred translocation partner in lipoma
chr12_-_719573 0.32 ENST00000397265.3
ninjurin 2
chr1_-_179112189 0.29 ENST00000512653.1
ENST00000344730.3
c-abl oncogene 2, non-receptor tyrosine kinase
chr18_+_21452804 0.29 ENST00000269217.6
laminin, alpha 3
chr17_+_7590734 0.28 ENST00000457584.2
WD repeat containing, antisense to TP53
chr1_-_52344471 0.23 ENST00000352171.7
ENST00000354831.7
nardilysin (N-arginine dibasic convertase)
chr2_-_65593784 0.20 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr3_-_151034734 0.20 ENST00000260843.4
G protein-coupled receptor 87
chr17_-_56595196 0.11 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
myotubularin related protein 4
chrX_-_48901012 0.10 ENST00000315869.7
transcription factor binding to IGHM enhancer 3
chr11_-_66103932 0.08 ENST00000311320.4
Ras and Rab interactor 1
chr21_-_36421535 0.03 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
runt-related transcription factor 1
chr9_-_139922631 0.02 ENST00000341511.6
ATP-binding cassette, sub-family A (ABC1), member 2
chrX_-_48937531 0.02 ENST00000473974.1
ENST00000475880.1
ENST00000396681.4
ENST00000553851.1
ENST00000471338.1
ENST00000476728.1
ENST00000376368.2
ENST00000485908.1
ENST00000376372.3
ENST00000376358.3
WD repeat domain 45
WD repeat domain phosphoinositide-interacting protein 4
chr3_+_48507621 0.02 ENST00000456089.1
three prime repair exonuclease 1

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 22.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
3.9 11.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
3.8 15.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
3.1 12.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
2.8 16.6 GO:0007296 vitellogenesis(GO:0007296)
2.7 18.6 GO:0009438 methylglyoxal metabolic process(GO:0009438)
2.5 22.9 GO:0030091 protein repair(GO:0030091)
2.5 10.0 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
2.5 12.4 GO:0015862 uridine transport(GO:0015862)
2.2 13.1 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
1.8 14.6 GO:0002036 regulation of L-glutamate transport(GO:0002036)
1.7 5.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.6 29.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.6 9.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.4 4.3 GO:1903028 positive regulation of opsonization(GO:1903028)
1.4 4.2 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
1.4 8.4 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
1.3 45.0 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.3 13.0 GO:0035092 sperm chromatin condensation(GO:0035092)
1.3 3.9 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
1.2 4.8 GO:1902031 regulation of NADP metabolic process(GO:1902031)
1.2 3.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.1 4.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.1 8.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
1.1 4.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
1.1 2.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
1.0 19.9 GO:0016540 protein autoprocessing(GO:0016540)
1.0 3.9 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.9 2.8 GO:1901656 glycoside transport(GO:1901656)
0.9 3.6 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.8 2.5 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.8 10.5 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.8 6.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.8 14.1 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.7 76.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.7 7.0 GO:0010265 SCF complex assembly(GO:0010265)
0.7 3.4 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.6 6.5 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.6 12.8 GO:0035855 megakaryocyte development(GO:0035855)
0.5 6.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.5 11.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.5 2.6 GO:0018158 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) protein oxidation(GO:0018158)
0.5 2.0 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.4 2.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.4 1.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.4 2.5 GO:0016554 cytidine to uridine editing(GO:0016554) DNA cytosine deamination(GO:0070383)
0.4 5.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.3 24.1 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.3 1.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 3.0 GO:0051014 actin filament severing(GO:0051014)
0.3 3.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.3 13.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.3 2.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.3 14.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.3 2.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.3 8.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.3 1.4 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.3 6.7 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 2.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 33.8 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.2 12.4 GO:0030224 monocyte differentiation(GO:0030224)
0.2 29.7 GO:0006334 nucleosome assembly(GO:0006334)
0.2 1.7 GO:0015816 glycine transport(GO:0015816)
0.2 4.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 16.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.2 13.4 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.2 1.7 GO:0001866 NK T cell proliferation(GO:0001866)
0.2 6.9 GO:0008608 mitotic spindle assembly checkpoint(GO:0007094) attachment of spindle microtubules to kinetochore(GO:0008608) spindle assembly checkpoint(GO:0071173)
0.2 8.8 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 0.5 GO:0097278 complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659)
0.2 1.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.8 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 9.1 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.1 3.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 7.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.5 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 2.9 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 6.1 GO:0006915 apoptotic process(GO:0006915)
0.1 7.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.4 GO:1901977 negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
0.1 8.8 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 0.5 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 10.3 GO:0051225 spindle assembly(GO:0051225)
0.1 6.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.3 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.7 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 26.3 GO:0007411 axon guidance(GO:0007411)
0.1 3.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.3 GO:0010842 retina layer formation(GO:0010842)
0.1 0.8 GO:0001765 membrane raft assembly(GO:0001765)
0.1 25.2 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.1 1.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 2.8 GO:0007417 central nervous system development(GO:0007417)
0.1 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 2.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 2.9 GO:0045214 sarcomere organization(GO:0045214)
0.0 2.1 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 3.1 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 2.0 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.8 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
0.0 7.6 GO:0006457 protein folding(GO:0006457)
0.0 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0014870 response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 4.3 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 8.8 GO:0045087 innate immune response(GO:0045087)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 43.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
4.7 14.1 GO:0033565 ESCRT-0 complex(GO:0033565)
3.8 15.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
2.5 22.2 GO:0005638 lamin filament(GO:0005638)
2.0 19.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
1.3 3.9 GO:0044393 microspike(GO:0044393)
1.3 18.0 GO:0031209 SCAR complex(GO:0031209)
1.2 26.5 GO:0005838 proteasome regulatory particle(GO:0005838)
1.1 10.3 GO:0070652 HAUS complex(GO:0070652)
1.1 12.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.1 17.0 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.0 7.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.0 11.6 GO:0005915 zonula adherens(GO:0005915) catenin complex(GO:0016342)
0.9 17.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.6 29.4 GO:0031430 M band(GO:0031430)
0.6 8.8 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.5 2.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.5 13.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 1.3 GO:0005607 laminin-2 complex(GO:0005607)
0.4 6.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 2.9 GO:0005827 polar microtubule(GO:0005827)
0.3 4.5 GO:0008290 F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.3 3.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 2.6 GO:0097413 Lewy body(GO:0097413)
0.3 1.1 GO:0031673 H zone(GO:0031673)
0.3 6.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 9.4 GO:0043034 costamere(GO:0043034)
0.2 33.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 2.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 4.1 GO:0031105 septin complex(GO:0031105)
0.2 1.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 17.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 8.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 12.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 2.1 GO:0005883 neurofilament(GO:0005883)
0.2 1.1 GO:0097452 GAIT complex(GO:0097452)
0.1 15.7 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.9 GO:0031143 pseudopodium(GO:0031143)
0.1 10.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.6 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.1 7.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.4 GO:0044754 autolysosome(GO:0044754)
0.1 3.6 GO:0043234 protein complex(GO:0043234)
0.1 17.0 GO:0034399 nuclear periphery(GO:0034399)
0.1 32.9 GO:0005819 spindle(GO:0005819)
0.1 20.1 GO:0005874 microtubule(GO:0005874)
0.1 4.8 GO:0005776 autophagosome(GO:0005776)
0.1 3.5 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 7.0 GO:0016605 PML body(GO:0016605)
0.1 2.1 GO:0016592 mediator complex(GO:0016592)
0.1 3.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 8.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 2.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 8.6 GO:0098794 postsynapse(GO:0098794)
0.0 18.2 GO:0016604 nuclear body(GO:0016604)
0.0 4.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.2 GO:0031902 late endosome membrane(GO:0031902)
0.0 5.9 GO:0000785 chromatin(GO:0000785)
0.0 1.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 6.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 9.4 GO:0009986 cell surface(GO:0009986)
0.0 71.1 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 22.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
7.3 43.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
5.1 15.2 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
2.7 29.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.3 18.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
2.3 9.1 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
1.8 24.8 GO:0030215 semaphorin receptor binding(GO:0030215)
1.6 4.8 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.6 18.7 GO:0004017 adenylate kinase activity(GO:0004017)
1.3 52.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.3 5.1 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
1.3 10.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.2 6.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
1.2 3.5 GO:0008859 exoribonuclease II activity(GO:0008859)
1.1 6.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.1 15.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.0 29.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.8 4.8 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.8 37.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.7 8.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.6 3.9 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.6 12.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.6 11.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.5 2.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.5 17.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.5 12.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.5 4.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.4 9.3 GO:0044548 S100 protein binding(GO:0044548)
0.4 1.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 2.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.4 2.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 14.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 1.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 6.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 1.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 11.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 0.6 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.2 2.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 2.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 2.5 GO:0019841 retinol binding(GO:0019841)
0.2 0.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 9.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 2.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 7.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 4.6 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 42.7 GO:0003924 GTPase activity(GO:0003924)
0.1 2.8 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.1 13.9 GO:0051082 unfolded protein binding(GO:0051082)
0.1 6.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 4.3 GO:0043531 ADP binding(GO:0043531)
0.1 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 15.1 GO:0000287 magnesium ion binding(GO:0000287)
0.1 1.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 2.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 4.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 8.3 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 7.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 5.0 GO:0005178 integrin binding(GO:0005178)
0.0 30.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 6.9 GO:0008201 heparin binding(GO:0008201)
0.0 6.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.1 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 10.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 5.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 12.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 24.0 GO:0003723 RNA binding(GO:0003723)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 37.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.4 34.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.4 11.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.4 8.8 PID ARF 3PATHWAY Arf1 pathway
0.3 24.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.3 16.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 29.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 7.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 9.7 PID RAS PATHWAY Regulation of Ras family activation
0.2 4.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 7.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 9.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 5.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 13.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 4.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 7.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 44.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.5 74.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.1 80.5 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.8 15.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.8 11.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.7 14.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.6 5.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.6 7.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.5 8.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.4 14.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 11.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 23.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 5.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.3 6.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.3 12.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 2.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 4.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 4.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 7.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 6.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 7.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 3.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 6.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 3.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 1.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane