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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for BARHL2
Z-value: 1.14
Motif logo
Transcription factors associated with BARHL2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
BARHL2
|
ENSG00000143032.7 | BarH like homeobox 2 |
Activity profile of BARHL2 motif
Sorted Z-values of BARHL2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of BARHL2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.2 | 74.9 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 5.8 | 17.5 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 4.8 | 14.3 | GO:1990523 | bone regeneration(GO:1990523) |
| 4.2 | 8.4 | GO:1904397 | negative regulation of neuromuscular junction development(GO:1904397) |
| 3.6 | 14.4 | GO:0001970 | positive regulation of activation of membrane attack complex(GO:0001970) |
| 2.1 | 2.1 | GO:0060221 | retinal rod cell differentiation(GO:0060221) |
| 1.7 | 5.1 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 1.7 | 13.5 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 1.5 | 3.1 | GO:2001183 | negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183) |
| 1.3 | 3.9 | GO:0052331 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 1.2 | 25.7 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 1.2 | 4.7 | GO:1904749 | regulation of protein localization to nucleolus(GO:1904749) |
| 1.2 | 3.5 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 1.1 | 5.7 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 1.1 | 93.0 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 1.0 | 9.7 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.9 | 6.6 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.9 | 5.2 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.8 | 5.9 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.8 | 3.4 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.8 | 2.5 | GO:0099553 | trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) |
| 0.8 | 1.6 | GO:2001186 | negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) |
| 0.8 | 2.4 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 0.8 | 18.3 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.8 | 7.8 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.8 | 2.3 | GO:2000048 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.8 | 5.4 | GO:2000795 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.7 | 2.2 | GO:1904328 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 0.7 | 6.5 | GO:1902459 | positive regulation of stem cell population maintenance(GO:1902459) |
| 0.7 | 2.8 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.7 | 2.1 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.7 | 5.4 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.7 | 10.1 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
| 0.7 | 2.0 | GO:0071934 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 0.7 | 6.6 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.6 | 2.6 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.6 | 2.5 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
| 0.6 | 1.9 | GO:1903248 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 0.6 | 6.6 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.6 | 1.2 | GO:0010716 | negative regulation of extracellular matrix disassembly(GO:0010716) |
| 0.6 | 1.1 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 0.6 | 7.8 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.5 | 1.6 | GO:0007231 | osmosensory signaling pathway(GO:0007231) |
| 0.5 | 5.4 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.5 | 1.6 | GO:1901876 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 0.5 | 1.6 | GO:0006711 | estrogen catabolic process(GO:0006711) |
| 0.5 | 1.5 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.5 | 3.0 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.4 | 3.1 | GO:0023021 | termination of signal transduction(GO:0023021) |
| 0.4 | 3.1 | GO:0021842 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
| 0.4 | 1.7 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.4 | 2.5 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.4 | 3.3 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 0.4 | 1.2 | GO:0051541 | elastin metabolic process(GO:0051541) |
| 0.4 | 1.2 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 0.4 | 3.5 | GO:0009744 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.4 | 3.2 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.3 | 1.0 | GO:0035378 | carbon dioxide transmembrane transport(GO:0035378) |
| 0.3 | 5.1 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.3 | 1.0 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.3 | 6.3 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.3 | 3.6 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 0.3 | 2.9 | GO:0033087 | negative regulation of immature T cell proliferation(GO:0033087) |
| 0.3 | 1.6 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 0.3 | 2.5 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.3 | 1.9 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.3 | 2.5 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.3 | 2.5 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.3 | 2.2 | GO:0042426 | choline catabolic process(GO:0042426) |
| 0.3 | 3.4 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 0.3 | 2.0 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.3 | 1.4 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 0.3 | 5.5 | GO:1904706 | negative regulation of vascular smooth muscle cell proliferation(GO:1904706) |
| 0.3 | 1.9 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.3 | 1.8 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.3 | 2.4 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.3 | 1.0 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.3 | 2.3 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.3 | 5.1 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.3 | 3.1 | GO:0009642 | response to light intensity(GO:0009642) |
| 0.3 | 7.3 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.2 | 0.7 | GO:0021650 | vestibulocochlear nerve formation(GO:0021650) |
| 0.2 | 3.2 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.2 | 0.9 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
| 0.2 | 4.4 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.2 | 12.8 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.2 | 0.9 | GO:0060748 | tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) |
| 0.2 | 4.4 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.2 | 1.1 | GO:0044026 | DNA hypermethylation(GO:0044026) |
| 0.2 | 3.3 | GO:0006558 | L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222) |
| 0.2 | 1.1 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
| 0.2 | 1.3 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 0.2 | 0.6 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.2 | 1.5 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.2 | 1.3 | GO:0009082 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.2 | 10.4 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.2 | 1.0 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.2 | 1.0 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.2 | 1.0 | GO:0097102 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
| 0.2 | 0.4 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.2 | 1.2 | GO:0070092 | response to selenium ion(GO:0010269) regulation of glucagon secretion(GO:0070092) |
| 0.2 | 1.4 | GO:0009753 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
| 0.2 | 1.1 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.2 | 1.5 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
| 0.2 | 2.4 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.2 | 0.5 | GO:0050883 | musculoskeletal movement, spinal reflex action(GO:0050883) |
| 0.2 | 1.6 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.2 | 1.1 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
| 0.2 | 1.2 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.2 | 0.5 | GO:0051697 | protein delipidation(GO:0051697) |
| 0.2 | 4.3 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.2 | 0.5 | GO:0048733 | sebaceous gland development(GO:0048733) |
| 0.2 | 2.2 | GO:0072126 | positive regulation of glomerular mesangial cell proliferation(GO:0072126) |
| 0.2 | 0.9 | GO:0030070 | insulin processing(GO:0030070) |
| 0.2 | 0.3 | GO:0071048 | nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048) |
| 0.2 | 3.1 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.2 | 1.1 | GO:0009804 | coumarin metabolic process(GO:0009804) |
| 0.2 | 0.6 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.2 | 5.3 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.2 | 1.2 | GO:0043305 | negative regulation of mast cell degranulation(GO:0043305) |
| 0.2 | 1.4 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.2 | 3.1 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.2 | 3.9 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 1.3 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.1 | 1.2 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.1 | 0.7 | GO:0050955 | thermoception(GO:0050955) |
| 0.1 | 0.7 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 0.1 | 1.3 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.1 | 1.8 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.1 | 0.5 | GO:0042574 | retinal metabolic process(GO:0042574) |
| 0.1 | 2.2 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.1 | 0.7 | GO:0038169 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 0.1 | 4.0 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.1 | 0.9 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.1 | 2.4 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.1 | 3.4 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.1 | 0.4 | GO:0018874 | benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605) |
| 0.1 | 0.9 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.1 | 1.1 | GO:0030450 | regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027) |
| 0.1 | 1.0 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.1 | 5.1 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.1 | 0.9 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 0.1 | 0.6 | GO:0070829 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 0.1 | 0.6 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.1 | 5.4 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.1 | 0.4 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
| 0.1 | 1.5 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.1 | 1.2 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.1 | 1.1 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.1 | 0.8 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.1 | 0.3 | GO:0043012 | regulation of fusion of sperm to egg plasma membrane(GO:0043012) |
| 0.1 | 0.5 | GO:0034334 | adherens junction maintenance(GO:0034334) |
| 0.1 | 0.7 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.1 | 0.8 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.1 | 0.7 | GO:0010519 | negative regulation of phospholipase activity(GO:0010519) |
| 0.1 | 0.6 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.1 | 4.4 | GO:0007603 | phototransduction, visible light(GO:0007603) |
| 0.1 | 0.7 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.1 | 2.4 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.1 | 2.4 | GO:0030728 | ovulation(GO:0030728) |
| 0.1 | 5.9 | GO:0008542 | visual learning(GO:0008542) |
| 0.1 | 0.9 | GO:2001135 | constitutive secretory pathway(GO:0045054) regulation of endocytic recycling(GO:2001135) |
| 0.1 | 1.6 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
| 0.1 | 0.3 | GO:0044793 | negative regulation by host of viral process(GO:0044793) |
| 0.1 | 1.6 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.1 | 1.0 | GO:0097283 | keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) |
| 0.1 | 1.1 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.1 | 0.3 | GO:0071435 | potassium ion export(GO:0071435) regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159) |
| 0.1 | 3.5 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.1 | 0.5 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.1 | 0.4 | GO:0051597 | response to methylmercury(GO:0051597) |
| 0.1 | 1.2 | GO:0006606 | protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593) |
| 0.1 | 2.5 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 3.8 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
| 0.1 | 1.5 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 0.7 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.1 | 6.5 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.1 | 0.7 | GO:0000050 | urea cycle(GO:0000050) |
| 0.1 | 3.3 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.1 | 1.3 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.1 | 0.4 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.1 | 11.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 0.8 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.1 | 0.3 | GO:0010511 | regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
| 0.1 | 0.8 | GO:0046548 | retinal rod cell development(GO:0046548) |
| 0.1 | 2.0 | GO:0010737 | protein kinase A signaling(GO:0010737) |
| 0.1 | 2.2 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.1 | 4.7 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.1 | 2.3 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.1 | 0.5 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
| 0.1 | 2.2 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 0.1 | 1.2 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.1 | 0.4 | GO:0052565 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 0.1 | 1.4 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.1 | 5.9 | GO:0070268 | cornification(GO:0070268) |
| 0.1 | 0.5 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.1 | 2.4 | GO:0046426 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.1 | 0.5 | GO:0007632 | visual behavior(GO:0007632) |
| 0.1 | 0.6 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 3.0 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 0.4 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.1 | 0.5 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) regulation of branching morphogenesis of a nerve(GO:2000172) |
| 0.1 | 0.9 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.0 | 2.1 | GO:0031102 | neuron projection regeneration(GO:0031102) |
| 0.0 | 0.7 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 0.0 | 1.3 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.3 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 0.2 | GO:2001206 | positive regulation of bone development(GO:1903012) positive regulation of osteoclast development(GO:2001206) |
| 0.0 | 3.5 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.8 | GO:0010762 | regulation of fibroblast migration(GO:0010762) |
| 0.0 | 0.2 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.0 | 0.4 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.0 | 0.4 | GO:0015865 | purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868) |
| 0.0 | 5.4 | GO:0048839 | inner ear development(GO:0048839) |
| 0.0 | 0.4 | GO:0006578 | amino-acid betaine biosynthetic process(GO:0006578) |
| 0.0 | 0.3 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.9 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.0 | 0.3 | GO:0009584 | detection of visible light(GO:0009584) |
| 0.0 | 0.7 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 0.0 | 0.4 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.0 | 0.4 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.0 | 1.0 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 0.8 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.3 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.0 | 0.6 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 0.7 | GO:0034122 | negative regulation of toll-like receptor signaling pathway(GO:0034122) cytoplasmic sequestering of transcription factor(GO:0042994) |
| 0.0 | 0.7 | GO:0009952 | anterior/posterior pattern specification(GO:0009952) |
| 0.0 | 0.3 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.0 | 0.3 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 0.0 | 0.6 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.4 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.0 | 0.8 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.2 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.0 | 0.3 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.2 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.0 | 0.6 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
| 0.0 | 2.6 | GO:0050953 | visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953) |
| 0.0 | 0.7 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.0 | 0.4 | GO:1990778 | protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778) |
| 0.0 | 0.3 | GO:0060850 | regulation of transcription involved in cell fate commitment(GO:0060850) |
| 0.0 | 0.1 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.0 | 0.3 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.8 | GO:0006305 | DNA alkylation(GO:0006305) DNA methylation(GO:0006306) |
| 0.0 | 0.4 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.5 | GO:0014823 | response to activity(GO:0014823) |
| 0.0 | 1.2 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 2.0 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.6 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 0.1 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 1.2 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.0 | 0.1 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 0.0 | 0.2 | GO:0046606 | negative regulation of centrosome cycle(GO:0046606) |
| 0.0 | 0.3 | GO:0097502 | mannosylation(GO:0097502) |
| 0.0 | 0.1 | GO:0044705 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
| 0.0 | 0.1 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
| 0.0 | 0.2 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.9 | 166.4 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 1.7 | 5.2 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 1.1 | 5.6 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 1.1 | 3.4 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 1.1 | 13.5 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.9 | 7.3 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.9 | 2.7 | GO:0031523 | Myb complex(GO:0031523) |
| 0.7 | 9.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.7 | 3.6 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.6 | 1.9 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.5 | 6.3 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.5 | 2.1 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.5 | 8.9 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.5 | 5.9 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.5 | 1.4 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 0.5 | 1.8 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 0.4 | 5.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.4 | 2.1 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 0.4 | 3.7 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.4 | 2.8 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.4 | 2.3 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.3 | 19.2 | GO:0002102 | podosome(GO:0002102) |
| 0.3 | 3.5 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.3 | 11.6 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.3 | 25.1 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.3 | 1.4 | GO:0030430 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
| 0.3 | 1.6 | GO:1990357 | terminal web(GO:1990357) |
| 0.3 | 1.3 | GO:0000801 | central element(GO:0000801) |
| 0.3 | 4.7 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.2 | 2.7 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.2 | 26.8 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.2 | 6.0 | GO:0090665 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.2 | 4.2 | GO:0042599 | lamellar body(GO:0042599) |
| 0.2 | 11.8 | GO:0034358 | plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777) |
| 0.2 | 0.8 | GO:0035838 | growing cell tip(GO:0035838) |
| 0.2 | 1.0 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.2 | 0.7 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 1.6 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.2 | 0.6 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.1 | 0.7 | GO:0071546 | pi-body(GO:0071546) |
| 0.1 | 1.9 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 4.3 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 0.9 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.1 | 1.8 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 3.3 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.1 | 1.0 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 0.7 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.1 | 0.3 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
| 0.1 | 0.8 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.1 | 2.2 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.1 | 1.4 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 0.5 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.1 | 0.9 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.1 | 2.1 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 4.9 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.1 | 5.3 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 1.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 2.1 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 0.5 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 14.9 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 6.9 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 1.1 | GO:0097386 | glial cell projection(GO:0097386) |
| 0.1 | 0.7 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.1 | 0.9 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 1.9 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 1.4 | GO:0009986 | cell surface(GO:0009986) |
| 0.1 | 0.5 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.1 | 0.9 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 4.1 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 1.5 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 0.6 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.1 | 3.0 | GO:0005902 | microvillus(GO:0005902) |
| 0.1 | 2.3 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 4.3 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 5.7 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 1.3 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.9 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 1.1 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 2.6 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 1.6 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 3.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 1.2 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.0 | 9.0 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 4.0 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 1.8 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 2.6 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 1.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 3.1 | GO:0044853 | plasma membrane raft(GO:0044853) |
| 0.0 | 0.4 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.0 | 0.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.7 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.0 | 0.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.4 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 0.7 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 0.2 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 6.3 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 1.2 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 10.7 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 6.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 1.2 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.4 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 2.1 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.3 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 1.1 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 1.2 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 2.5 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 0.0 | 0.7 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 1.6 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 2.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 0.6 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.5 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.2 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.4 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 0.4 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.1 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 0.4 | GO:0045177 | apical part of cell(GO:0045177) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 2.7 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
| 2.1 | 8.4 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 1.3 | 6.6 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 1.2 | 3.5 | GO:0070052 | collagen V binding(GO:0070052) |
| 1.0 | 100.2 | GO:0005518 | collagen binding(GO:0005518) |
| 1.0 | 1.0 | GO:0035379 | carbon dioxide transmembrane transporter activity(GO:0035379) |
| 1.0 | 3.1 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 1.0 | 3.1 | GO:0017129 | triglyceride binding(GO:0017129) |
| 1.0 | 107.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.9 | 3.5 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.8 | 4.2 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.8 | 3.3 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 0.7 | 4.3 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.7 | 5.7 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.7 | 2.7 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.7 | 2.0 | GO:0015403 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.7 | 15.0 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.6 | 1.9 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 0.6 | 1.9 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.5 | 1.6 | GO:0030366 | molybdopterin synthase activity(GO:0030366) |
| 0.5 | 1.6 | GO:0070984 | SET domain binding(GO:0070984) |
| 0.5 | 2.6 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.5 | 1.5 | GO:0046848 | hydroxyapatite binding(GO:0046848) |
| 0.5 | 3.8 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.5 | 1.4 | GO:0004040 | amidase activity(GO:0004040) fucose binding(GO:0042806) |
| 0.5 | 7.5 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.4 | 1.3 | GO:0004139 | deoxyribose-phosphate aldolase activity(GO:0004139) |
| 0.4 | 2.5 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.4 | 2.4 | GO:0004447 | iodide peroxidase activity(GO:0004447) |
| 0.4 | 2.8 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.4 | 9.9 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.4 | 4.3 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.4 | 1.6 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 0.4 | 1.5 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.4 | 3.7 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.4 | 3.6 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.3 | 2.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.3 | 6.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.3 | 3.1 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.3 | 1.4 | GO:0047023 | androsterone dehydrogenase activity(GO:0047023) |
| 0.3 | 1.0 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.3 | 1.6 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.3 | 4.4 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.3 | 3.1 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.3 | 3.1 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.3 | 2.3 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.3 | 0.8 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.3 | 1.9 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.3 | 4.2 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.3 | 2.1 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.3 | 4.7 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.3 | 0.8 | GO:0005171 | hepatocyte growth factor receptor binding(GO:0005171) |
| 0.2 | 1.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.2 | 6.6 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.2 | 1.0 | GO:0070137 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.2 | 2.3 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.2 | 1.6 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294) |
| 0.2 | 2.5 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.2 | 2.6 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.2 | 1.5 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.2 | 0.6 | GO:0008267 | poly-glutamine tract binding(GO:0008267) |
| 0.2 | 0.6 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.2 | 1.3 | GO:0004084 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.2 | 1.0 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.2 | 5.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.2 | 4.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.2 | 2.2 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.2 | 1.8 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.2 | 0.5 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.2 | 1.9 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.2 | 0.3 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.2 | 0.6 | GO:0004356 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.2 | 4.0 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 3.7 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.2 | 1.4 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.2 | 2.4 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.2 | 0.9 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.2 | 2.3 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.1 | 5.1 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.1 | 0.7 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.1 | 1.0 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.1 | 2.2 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.1 | 0.8 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.1 | 6.6 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.1 | 0.7 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.1 | 19.2 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 0.5 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 1.0 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 3.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.9 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.1 | 0.3 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.1 | 0.6 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.1 | 5.4 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 0.4 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
| 0.1 | 1.0 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 15.6 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 0.4 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.1 | 1.8 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 0.5 | GO:0002046 | opsin binding(GO:0002046) |
| 0.1 | 0.6 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.1 | 3.1 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 0.4 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.1 | 2.5 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 0.3 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 0.1 | 9.2 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.1 | 0.5 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.1 | 0.5 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 1.4 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 0.5 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.1 | 1.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 0.4 | GO:0060175 | brain-derived neurotrophic factor-activated receptor activity(GO:0060175) |
| 0.1 | 0.6 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 1.9 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 1.1 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 1.2 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.1 | 7.0 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.1 | 0.3 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 1.5 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.1 | 0.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 1.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.8 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.1 | 1.1 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.1 | 2.4 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.1 | 1.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 2.9 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.1 | 10.3 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.1 | 0.9 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.1 | 1.0 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.1 | 1.2 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 1.1 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 2.3 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 1.4 | GO:0019956 | chemokine binding(GO:0019956) |
| 0.1 | 1.3 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 5.4 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) |
| 0.1 | 0.2 | GO:0001034 | RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034) |
| 0.1 | 0.7 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.1 | 0.9 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 5.3 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.7 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 2.4 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.3 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.0 | 0.8 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.0 | 2.2 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.0 | 0.3 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.0 | 0.4 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.0 | 1.3 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.8 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 1.6 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.0 | 0.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.9 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.7 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 0.9 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.4 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.0 | 3.0 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 0.0 | 0.6 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.4 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
| 0.0 | 0.4 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.0 | 22.5 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 1.0 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.4 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.3 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.0 | 0.3 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 2.7 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 7.2 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.9 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 2.9 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.3 | GO:0051378 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.0 | 1.8 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.4 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.0 | 3.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.1 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.0 | 0.2 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 0.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 1.5 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 0.1 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.0 | 0.8 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.2 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.0 | 0.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.9 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 1.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 2.2 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 1.0 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 1.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.6 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.4 | GO:0050662 | coenzyme binding(GO:0050662) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 91.5 | NABA COLLAGENS | Genes encoding collagen proteins |
| 1.7 | 94.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.5 | 10.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.3 | 7.3 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.2 | 6.5 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.2 | 14.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.2 | 6.6 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.2 | 1.2 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.1 | 31.8 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 5.8 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.1 | 2.9 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.1 | 13.3 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 10.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 0.7 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.1 | 5.4 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 1.1 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 2.3 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 2.8 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 3.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 7.1 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 1.9 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 7.5 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.1 | 3.1 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 4.3 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 2.5 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 1.9 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 4.4 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.1 | 3.6 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 2.7 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.1 | 3.6 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 1.6 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.1 | 5.9 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 1.4 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.1 | 2.0 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 1.5 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 3.3 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 2.8 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.5 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 2.9 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.9 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.0 | 10.4 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.0 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.8 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.5 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 2.4 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.7 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.0 | 1.0 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.7 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 0.1 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.0 | 3.6 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.4 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.2 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.3 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 73.2 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 1.4 | 91.7 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 1.1 | 15.0 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.6 | 16.0 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.6 | 12.6 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.5 | 10.1 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.4 | 6.6 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.4 | 6.4 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.2 | 2.3 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.2 | 6.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.2 | 3.9 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.2 | 4.3 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.2 | 5.5 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.2 | 5.3 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 5.2 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.2 | 3.0 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.2 | 11.0 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 1.0 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.2 | 7.0 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.2 | 1.4 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.2 | 2.2 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
| 0.2 | 2.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.2 | 3.4 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.2 | 5.6 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.1 | 4.6 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.1 | 4.4 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.1 | 1.0 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.1 | 4.5 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 2.5 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.1 | 5.5 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 12.3 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 4.0 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 1.1 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.1 | 2.4 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 1.3 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 3.7 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 3.1 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 4.0 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 2.8 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 1.6 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 1.6 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.1 | 4.0 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 0.8 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 4.9 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 0.9 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 3.4 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.1 | 1.1 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 0.7 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.0 | 1.3 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 1.0 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.7 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.0 | 0.5 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.6 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.7 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.0 | 2.6 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 1.0 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 2.3 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 3.2 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 2.3 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.6 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.0 | 0.9 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.0 | 0.3 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 1.2 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.7 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 1.1 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 0.4 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.4 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 1.8 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.0 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.4 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 0.3 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.2 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.0 | 0.6 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.4 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 1.2 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 0.4 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 0.4 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 0.0 | 0.4 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.3 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 1.8 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |