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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for BATF

Z-value: 2.26

Motif logo

Transcription factors associated with BATF

Gene Symbol Gene ID Gene Info
ENSG00000156127.6 basic leucine zipper ATF-like transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BATFhg19_v2_chr14_+_75988851_75988903-0.236.1e-04Click!

Activity profile of BATF motif

Sorted Z-values of BATF motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_223889285 54.48 ENST00000433674.2
calpain 2, (m/II) large subunit
chr6_-_31704282 39.29 ENST00000375784.3
ENST00000375779.2
chloride intracellular channel 1
chr11_-_33744487 38.26 ENST00000426650.2
CD59 molecule, complement regulatory protein
chr5_+_159848854 37.54 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr11_-_33743952 36.14 ENST00000534312.1
CD59 molecule, complement regulatory protein
chr6_+_63921399 34.58 ENST00000356170.3
FK506 binding protein 1C
chr16_-_69760409 32.59 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NAD(P)H dehydrogenase, quinone 1
chr2_+_10262442 30.14 ENST00000360566.2
ribonucleotide reductase M2
chr1_-_151965048 30.05 ENST00000368809.1
S100 calcium binding protein A10
chr17_-_79481666 28.22 ENST00000575659.1
actin, gamma 1
chr4_-_84035905 27.75 ENST00000311507.4
placenta-specific 8
chr3_-_149095652 27.61 ENST00000305366.3
transmembrane 4 L six family member 1
chr3_-_81792780 27.41 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr2_-_106013400 27.22 ENST00000409807.1
four and a half LIM domains 2
chr5_+_135394840 27.16 ENST00000503087.1
transforming growth factor, beta-induced, 68kDa
chr4_-_174254823 26.84 ENST00000438704.2
high mobility group box 2
chr5_+_159848807 26.20 ENST00000352433.5
pituitary tumor-transforming 1
chr8_+_55047763 25.65 ENST00000260102.4
ENST00000519831.1
mitochondrial ribosomal protein L15
chr15_-_60690163 25.02 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
annexin A2
chr5_+_73980965 24.08 ENST00000261416.7
hexosaminidase B (beta polypeptide)
chr22_+_23241661 23.89 ENST00000390322.2
immunoglobulin lambda joining 2
chr11_-_2950642 23.70 ENST00000314222.4
pleckstrin homology-like domain, family A, member 2
chr6_+_63921351 22.79 ENST00000370659.1
FK506 binding protein 1C
chr1_-_24126023 22.61 ENST00000429356.1
UDP-galactose-4-epimerase
chr2_-_85637459 22.56 ENST00000409921.1
capping protein (actin filament), gelsolin-like
chr20_+_47835884 22.34 ENST00000371764.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr5_+_65222384 22.17 ENST00000380943.2
ENST00000416865.2
ENST00000380939.2
ENST00000380936.1
ENST00000380935.1
erbb2 interacting protein
chr6_+_44194762 22.09 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr9_+_75766652 21.40 ENST00000257497.6
annexin A1
chr1_-_225616515 21.31 ENST00000338179.2
ENST00000425080.1
lamin B receptor
chr6_-_138428613 20.67 ENST00000421351.3
PERP, TP53 apoptosis effector
chr11_-_64013288 20.54 ENST00000542235.1
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr7_-_87856303 20.50 ENST00000394641.3
sorcin
chr14_+_35747825 20.48 ENST00000540871.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr1_+_26605618 20.26 ENST00000270792.5
SH3 domain binding glutamic acid-rich protein like 3
chr12_+_96252706 20.23 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr1_-_113247543 19.80 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr1_+_158979686 19.55 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr1_-_225615599 19.27 ENST00000421383.1
ENST00000272163.4
lamin B receptor
chr9_+_42704004 19.22 ENST00000457288.1
COBW domain containing 7
chr2_+_90060377 19.16 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr1_-_209824643 19.07 ENST00000391911.1
ENST00000415782.1
laminin, beta 3
chr1_+_26606608 18.94 ENST00000319041.6
SH3 domain binding glutamic acid-rich protein like 3
chr10_+_17270214 18.75 ENST00000544301.1
vimentin
chr12_+_69979113 18.61 ENST00000299300.6
chaperonin containing TCP1, subunit 2 (beta)
chr7_-_7680601 18.54 ENST00000396682.2
replication protein A3, 14kDa
chr1_+_158979792 18.47 ENST00000359709.3
ENST00000430894.2
interferon, gamma-inducible protein 16
chr15_+_80364901 18.19 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
zinc finger, AN1-type domain 6
chr2_-_152146385 18.14 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr1_+_158900568 18.00 ENST00000458222.1
pyrin and HIN domain family, member 1
chr6_-_24667180 17.86 ENST00000545995.1
tyrosyl-DNA phosphodiesterase 2
chr3_+_33155525 17.83 ENST00000449224.1
cartilage associated protein
chr1_-_152009460 17.75 ENST00000271638.2
S100 calcium binding protein A11
chr6_-_24666819 17.66 ENST00000341060.3
tyrosyl-DNA phosphodiesterase 2
chr14_+_55590646 17.54 ENST00000553493.1
lectin, galactoside-binding, soluble, 3
chr17_+_18625336 17.53 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
tripartite motif containing 16-like
chr5_+_65222299 17.45 ENST00000284037.5
erbb2 interacting protein
chr10_+_106014468 17.32 ENST00000369710.4
ENST00000369713.5
ENST00000445155.1
glutathione S-transferase omega 1
chr7_+_73106926 17.26 ENST00000453316.1
Williams Beuren syndrome chromosome region 22
chr2_-_85641162 17.25 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
capping protein (actin filament), gelsolin-like
chr22_+_23046750 17.17 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr3_+_30647994 16.95 ENST00000295754.5
transforming growth factor, beta receptor II (70/80kDa)
chr3_+_30648066 16.93 ENST00000359013.4
transforming growth factor, beta receptor II (70/80kDa)
chr11_+_101983176 16.63 ENST00000524575.1
Yes-associated protein 1
chr2_-_89417335 16.61 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr2_+_201981527 16.59 ENST00000441224.1
CASP8 and FADD-like apoptosis regulator
chr1_+_156084461 16.50 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
lamin A/C
chr1_+_158979680 16.46 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr12_-_53343602 16.43 ENST00000546897.1
ENST00000552551.1
keratin 8
chr11_-_64013663 16.38 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_-_73150629 16.27 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
hematological and neurological expressed 1
chr8_-_124037890 16.27 ENST00000519018.1
ENST00000523036.1
derlin 1
chr5_+_138089100 16.18 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr12_+_123237321 16.17 ENST00000280557.6
ENST00000455982.2
density-regulated protein
chr13_+_28195988 16.12 ENST00000399697.3
ENST00000399696.1
polymerase (RNA) I polypeptide D, 16kDa
chr4_-_84035868 15.94 ENST00000426923.2
ENST00000509973.1
placenta-specific 8
chr19_+_14672755 15.90 ENST00000594545.1
trans-2,3-enoyl-CoA reductase
chr2_+_90198535 15.80 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr12_+_75874460 15.80 ENST00000266659.3
GLI pathogenesis-related 1
chr11_-_33744256 15.64 ENST00000415002.2
ENST00000437761.2
ENST00000445143.2
CD59 molecule, complement regulatory protein
chr12_-_15104040 15.59 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr14_+_20937538 15.54 ENST00000361505.5
ENST00000553591.1
purine nucleoside phosphorylase
chr1_+_148560843 15.37 ENST00000442702.2
ENST00000369187.3
neuroblastoma breakpoint family, member 15
chr15_-_85259294 15.36 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11 homolog A (S. cerevisiae)
chr2_+_192141611 15.35 ENST00000392316.1
myosin IB
chr1_+_156095951 15.34 ENST00000448611.2
ENST00000368297.1
lamin A/C
chrX_+_64887512 15.32 ENST00000360270.5
moesin
chr3_+_150321068 15.04 ENST00000471696.1
ENST00000477889.1
ENST00000485923.1
Selenoprotein T
chr6_-_24667232 14.98 ENST00000378198.4
tyrosyl-DNA phosphodiesterase 2
chr2_+_201997492 14.93 ENST00000494258.1
CASP8 and FADD-like apoptosis regulator
chr1_-_89458636 14.83 ENST00000370486.1
ENST00000399794.2
cysteine conjugate-beta lyase 2
RNA binding motif protein, X-linked-like 1
chr12_+_13349650 14.78 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
epithelial membrane protein 1
chr3_+_127771212 14.75 ENST00000243253.3
ENST00000481210.1
Sec61 alpha 1 subunit (S. cerevisiae)
chr2_+_109204909 14.53 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr15_-_85259330 14.47 ENST00000560266.1
SEC11 homolog A (S. cerevisiae)
chr5_+_172386419 14.45 ENST00000265100.2
ENST00000519239.1
ribosomal protein L26-like 1
chr2_-_170681324 14.29 ENST00000409340.1
methyltransferase like 5
chr10_+_88854926 14.27 ENST00000298784.1
ENST00000298786.4
family with sequence similarity 35, member A
chr15_-_55563072 14.05 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A, member RAS oncogene family
chr5_+_72143988 13.91 ENST00000506351.2
transportin 1
chr2_+_201936707 13.87 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr2_-_89513402 13.87 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr7_+_48128194 13.84 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
uridine phosphorylase 1
chr3_-_150320937 13.79 ENST00000479209.1
stress-associated endoplasmic reticulum protein 1
chr17_-_8113542 13.78 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr13_-_41593425 13.76 ENST00000239882.3
E74-like factor 1 (ets domain transcription factor)
chr14_-_94854926 13.67 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr9_-_127177703 13.54 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
proteasome (prosome, macropain) subunit, beta type, 7
chr7_+_55177416 13.53 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr3_-_49066811 13.49 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr18_-_33702078 13.48 ENST00000586829.1
solute carrier family 39 (zinc transporter), member 6
chr15_+_22892663 13.39 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
cytoplasmic FMR1 interacting protein 1
chr7_+_48128316 13.33 ENST00000341253.4
uridine phosphorylase 1
chr12_-_56120865 13.31 ENST00000548898.1
ENST00000552067.1
CD63 molecule
chr6_-_41909561 13.12 ENST00000372991.4
cyclin D3
chr13_+_53216565 12.78 ENST00000357495.2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr7_+_30634297 12.77 ENST00000389266.3
glycyl-tRNA synthetase
chr2_+_90139056 12.77 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr7_-_87856280 12.75 ENST00000490437.1
ENST00000431660.1
sorcin
chr11_+_35198118 12.72 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44 molecule (Indian blood group)
chr6_-_2842087 12.72 ENST00000537185.1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr3_-_185641681 12.71 ENST00000259043.7
transformer 2 beta homolog (Drosophila)
chr6_-_159239257 12.66 ENST00000337147.7
ENST00000392177.4
ezrin
chrX_+_23682379 12.62 ENST00000379349.1
peroxiredoxin 4
chr11_-_65667997 12.54 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr2_-_3595547 12.52 ENST00000438485.1
Uncharacterized protein
chr17_-_7590745 12.48 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
tumor protein p53
chr18_+_3247779 12.42 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr11_-_65667884 12.29 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr19_+_49377575 12.19 ENST00000600406.1
protein phosphatase 1, regulatory subunit 15A
chr17_+_49230897 12.15 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr4_-_143227088 12.11 ENST00000511838.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr15_-_85259384 12.08 ENST00000455959.3
SEC11 homolog A (S. cerevisiae)
chr3_-_47823298 12.07 ENST00000254480.5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr4_+_17616253 12.07 ENST00000237380.7
mediator complex subunit 28
chr8_-_102217796 12.06 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
zinc finger protein 706
chr2_+_27435734 12.05 ENST00000419744.1
all-trans retinoic acid-induced differentiation factor
chr19_+_52932435 12.01 ENST00000301085.4
zinc finger protein 534
chr1_+_174844645 11.99 ENST00000486220.1
RAB GTPase activating protein 1-like
chr11_+_18417813 11.96 ENST00000540430.1
ENST00000379412.5
lactate dehydrogenase A
chr12_-_76478686 11.96 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr11_+_20385327 11.95 ENST00000451739.2
ENST00000532505.1
HIV-1 Tat interactive protein 2, 30kDa
chr9_+_71819927 11.95 ENST00000535702.1
tight junction protein 2
chr20_-_1373682 11.94 ENST00000381724.3
FK506 binding protein 1A, 12kDa
chr2_-_89266286 11.82 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr12_+_75874580 11.80 ENST00000456650.3
GLI pathogenesis-related 1
chr17_+_1936687 11.75 ENST00000570477.1
diphthamide biosynthesis 1
chr17_+_21191341 11.63 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
mitogen-activated protein kinase kinase 3
chr8_-_67977178 11.63 ENST00000517736.1
COP9 signalosome subunit 5
chr7_+_128399002 11.52 ENST00000493278.1
calumenin
chr5_-_179051579 11.51 ENST00000505811.1
ENST00000515714.1
ENST00000513225.1
ENST00000503664.1
ENST00000356731.5
ENST00000523137.1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr2_+_161993412 11.45 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr12_-_2986107 11.43 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
forkhead box M1
chr3_+_160117087 11.43 ENST00000357388.3
structural maintenance of chromosomes 4
chr19_+_13051206 11.41 ENST00000586760.1
calreticulin
chr1_-_193074504 11.40 ENST00000367439.3
glutaredoxin 2
chr5_+_32585605 11.40 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1 homolog (S. cerevisiae)
chr3_-_149093499 11.40 ENST00000472441.1
transmembrane 4 L six family member 1
chr18_-_51751132 11.36 ENST00000256429.3
methyl-CpG binding domain protein 2
chr12_-_56122426 11.32 ENST00000551173.1
CD63 molecule
chrX_+_118602363 11.32 ENST00000317881.8
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr2_+_201997595 11.26 ENST00000470178.2
CASP8 and FADD-like apoptosis regulator
chr1_-_19746236 11.23 ENST00000375144.1
capping protein (actin filament) muscle Z-line, beta
chr6_+_24667257 11.22 ENST00000537591.1
ENST00000230048.4
acyl-CoA thioesterase 13
chr21_-_46237883 11.13 ENST00000397893.3
small ubiquitin-like modifier 3
chr12_-_76462713 11.05 ENST00000552056.1
nucleosome assembly protein 1-like 1
chr2_-_151344172 11.03 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr16_-_75681522 11.02 ENST00000568378.1
ENST00000568682.1
ENST00000570215.1
ENST00000319410.5
ENST00000302445.3
lysyl-tRNA synthetase
chr6_-_137539651 10.95 ENST00000543628.1
interferon gamma receptor 1
chr2_+_89923550 10.93 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr10_+_17686124 10.91 ENST00000377524.3
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr12_+_27863706 10.84 ENST00000081029.3
ENST00000538315.1
ENST00000542791.1
mitochondrial ribosomal protein S35
chr15_-_77376269 10.79 ENST00000558745.1
tetraspanin 3
chr15_+_89181974 10.78 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr5_-_96518907 10.78 ENST00000508447.1
ENST00000283109.3
RIO kinase 2
chr20_-_1373726 10.76 ENST00000400137.4
FK506 binding protein 1A, 12kDa
chr17_-_65362678 10.75 ENST00000357146.4
ENST00000356126.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr17_-_39681578 10.74 ENST00000593096.1
keratin 19
chr12_-_50419177 10.73 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
Rac GTPase activating protein 1
chr1_+_45477819 10.71 ENST00000246337.4
uroporphyrinogen decarboxylase
chr2_+_216974020 10.64 ENST00000392132.2
ENST00000417391.1
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr1_-_246580705 10.64 ENST00000541742.1
SET and MYND domain containing 3
chr1_+_53392901 10.62 ENST00000371514.3
ENST00000528311.1
ENST00000371509.4
ENST00000407246.2
ENST00000371513.5
sterol carrier protein 2
chr2_-_113594279 10.62 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr12_-_56122761 10.59 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
CD63 molecule
chr1_-_109968973 10.53 ENST00000271308.4
ENST00000538610.1
proteasome (prosome, macropain) subunit, alpha type, 5
chrX_-_109561294 10.51 ENST00000372059.2
ENST00000262844.5
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr12_-_48099754 10.51 ENST00000380650.4
RNA polymerase II associated protein 3
chr12_+_16109519 10.44 ENST00000526530.1
deoxyribose-phosphate aldolase (putative)
chr3_+_133293278 10.44 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3 homolog (mouse)
chr12_-_48099773 10.36 ENST00000432584.3
ENST00000005386.3
RNA polymerase II associated protein 3
chr11_-_104817919 10.35 ENST00000533252.1
caspase 4, apoptosis-related cysteine peptidase
chr5_-_10761206 10.32 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr3_+_183894566 10.23 ENST00000439647.1
adaptor-related protein complex 2, mu 1 subunit
chr2_-_89459813 10.23 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr9_+_71820057 10.23 ENST00000539225.1
tight junction protein 2
chr2_+_89998789 10.20 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chrX_-_77225135 10.18 ENST00000458128.1
phosphoglycerate mutase family member 4
chr7_+_128379346 10.13 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
calumenin
chr15_-_59225758 10.11 ENST00000558486.1
ENST00000560682.1
ENST00000249736.7
ENST00000559880.1
ENST00000536328.1
SAFB-like, transcription modulator

Network of associatons between targets according to the STRING database.

First level regulatory network of BATF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
22.5 90.0 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
11.3 33.9 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
8.4 25.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
8.3 25.0 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
7.7 38.6 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
7.4 29.6 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
7.1 21.4 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
6.8 27.2 GO:0006218 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
6.2 18.6 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
6.0 18.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
6.0 17.9 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
5.9 23.8 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
5.9 17.8 GO:1901873 regulation of post-translational protein modification(GO:1901873)
5.9 23.4 GO:2000520 regulation of immunological synapse formation(GO:2000520)
5.7 28.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
5.5 32.9 GO:0022614 membrane to membrane docking(GO:0022614)
5.4 27.2 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
5.4 16.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
5.4 16.2 GO:0002188 translation reinitiation(GO:0002188)
5.3 74.0 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
5.2 15.5 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
5.0 49.5 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
4.8 24.1 GO:0007619 courtship behavior(GO:0007619)
4.8 14.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
4.6 13.8 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
4.5 13.5 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
4.4 22.1 GO:0015862 uridine transport(GO:0015862)
4.4 13.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
4.2 12.5 GO:0051097 negative regulation of helicase activity(GO:0051097) oxidative stress-induced premature senescence(GO:0090403) oligodendrocyte apoptotic process(GO:0097252)
4.1 24.8 GO:0007296 vitellogenesis(GO:0007296)
4.1 12.2 GO:1902310 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
4.0 4.0 GO:0006529 asparagine biosynthetic process(GO:0006529)
3.9 15.6 GO:0071461 cellular response to redox state(GO:0071461)
3.7 18.7 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
3.7 48.4 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
3.6 25.3 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
3.6 18.0 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
3.5 10.6 GO:1904430 negative regulation of t-circle formation(GO:1904430)
3.5 10.6 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
3.4 10.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
3.4 13.7 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
3.3 13.4 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
3.3 10.0 GO:0007518 myoblast fate determination(GO:0007518)
3.3 13.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
3.3 19.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
3.3 16.3 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
3.2 12.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
3.0 15.1 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
3.0 21.1 GO:0022417 protein maturation by protein folding(GO:0022417)
2.9 8.8 GO:1904933 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
2.9 8.7 GO:0033341 regulation of collagen binding(GO:0033341)
2.8 8.5 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
2.8 2.8 GO:0043335 protein unfolding(GO:0043335)
2.7 35.1 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
2.6 15.9 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
2.6 7.9 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
2.6 47.2 GO:0001765 membrane raft assembly(GO:0001765)
2.6 10.4 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
2.6 7.8 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
2.6 51.7 GO:0006465 signal peptide processing(GO:0006465)
2.6 7.7 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
2.5 10.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.4 24.5 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
2.4 36.6 GO:0006183 GTP biosynthetic process(GO:0006183)
2.4 31.7 GO:0019388 galactose catabolic process(GO:0019388)
2.4 7.3 GO:0070541 response to platinum ion(GO:0070541)
2.4 41.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
2.3 42.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
2.3 14.0 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
2.3 9.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
2.3 23.3 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
2.3 6.9 GO:0001923 B-1 B cell differentiation(GO:0001923)
2.3 9.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
2.2 11.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
2.2 22.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
2.2 11.2 GO:0002084 protein depalmitoylation(GO:0002084)
2.2 8.8 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
2.2 8.8 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
2.2 41.4 GO:0016540 protein autoprocessing(GO:0016540)
2.2 8.7 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
2.1 6.4 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
2.1 6.3 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
2.1 10.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
2.1 8.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
2.1 18.7 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
2.0 4.0 GO:1990523 bone regeneration(GO:1990523)
2.0 15.9 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
2.0 11.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
2.0 7.8 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
1.9 17.5 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
1.9 3.8 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
1.9 5.7 GO:0043418 homocysteine catabolic process(GO:0043418)
1.9 7.6 GO:0009438 methylglyoxal metabolic process(GO:0009438)
1.9 11.3 GO:1901029 adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
1.9 18.9 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
1.9 5.6 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
1.9 27.8 GO:0006089 lactate metabolic process(GO:0006089)
1.8 10.9 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
1.8 7.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.8 5.3 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.7 19.1 GO:0002934 desmosome organization(GO:0002934)
1.7 18.9 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
1.7 33.7 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
1.7 20.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
1.7 5.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.7 11.6 GO:0035897 proteolysis in other organism(GO:0035897)
1.7 19.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.7 9.9 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
1.6 8.2 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
1.6 8.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.6 4.9 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
1.6 17.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
1.6 6.4 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
1.6 12.8 GO:0006983 ER overload response(GO:0006983)
1.6 12.8 GO:0035092 sperm chromatin condensation(GO:0035092)
1.6 9.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.6 7.9 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
1.6 3.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
1.6 4.7 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.6 4.7 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
1.6 18.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
1.6 6.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
1.6 4.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.5 4.6 GO:0007290 spermatid nucleus elongation(GO:0007290)
1.5 9.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.5 68.8 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
1.5 1.5 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.5 9.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
1.5 132.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
1.5 7.5 GO:0018158 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) protein oxidation(GO:0018158)
1.5 5.9 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.5 23.8 GO:0060712 spongiotrophoblast layer development(GO:0060712)
1.5 4.4 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
1.5 11.8 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
1.4 11.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.4 5.7 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
1.4 15.6 GO:0038203 TORC2 signaling(GO:0038203)
1.4 2.8 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
1.4 12.6 GO:0030091 protein repair(GO:0030091)
1.4 8.4 GO:0006689 ganglioside catabolic process(GO:0006689)
1.4 58.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
1.4 16.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.4 5.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
1.4 9.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.4 4.1 GO:0006106 fumarate metabolic process(GO:0006106)
1.3 13.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.3 16.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.3 4.0 GO:1902031 regulation of NADP metabolic process(GO:1902031)
1.3 7.9 GO:0036490 regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492) positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
1.3 7.9 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
1.3 30.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
1.3 9.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
1.3 20.7 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
1.3 10.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.3 3.9 GO:0015680 intracellular copper ion transport(GO:0015680)
1.3 54.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
1.3 11.4 GO:0090344 negative regulation of cell aging(GO:0090344)
1.3 205.3 GO:0002377 immunoglobulin production(GO:0002377)
1.3 6.3 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
1.3 6.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.3 7.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.2 5.0 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
1.2 5.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.2 9.8 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
1.2 16.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.2 4.9 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
1.2 13.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
1.2 4.8 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
1.2 7.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
1.2 7.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.2 5.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
1.2 3.5 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
1.2 3.5 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.1 5.7 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
1.1 4.6 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
1.1 11.4 GO:0042262 DNA protection(GO:0042262)
1.1 6.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.1 11.3 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
1.1 32.4 GO:0031581 hemidesmosome assembly(GO:0031581)
1.1 12.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
1.1 5.4 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
1.1 6.4 GO:0090191 negative regulation of mesonephros development(GO:0061218) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
1.1 3.2 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
1.1 6.3 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
1.0 4.2 GO:0045218 zonula adherens maintenance(GO:0045218)
1.0 4.1 GO:0035641 locomotory exploration behavior(GO:0035641)
1.0 7.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
1.0 4.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.0 11.0 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
1.0 20.6 GO:0035855 megakaryocyte development(GO:0035855)
1.0 1.0 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
1.0 7.6 GO:0042407 cristae formation(GO:0042407)
1.0 6.7 GO:0046348 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.9 1.9 GO:0032679 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.9 3.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.9 4.6 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.9 68.0 GO:0070126 mitochondrial translational termination(GO:0070126)
0.9 2.7 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.9 12.7 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.9 4.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.9 3.6 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.9 11.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.9 8.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.9 8.8 GO:0070365 hepatocyte differentiation(GO:0070365)
0.9 3.5 GO:0048254 snoRNA localization(GO:0048254)
0.9 4.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.9 4.3 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.9 7.7 GO:2000507 cap-dependent translational initiation(GO:0002191) positive regulation of energy homeostasis(GO:2000507)
0.9 19.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.8 5.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.8 10.7 GO:1902969 mitotic DNA replication(GO:1902969)
0.8 50.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.8 131.0 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.8 19.2 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.8 24.0 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.8 2.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.8 3.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.8 8.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.7 5.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.7 6.7 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890) negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.7 2.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.7 2.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.7 0.7 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.7 2.1 GO:1990169 detoxification of copper ion(GO:0010273) detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501) stress response to copper ion(GO:1990169)
0.7 6.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.7 14.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.7 2.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.7 3.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.7 10.1 GO:0050684 regulation of mRNA processing(GO:0050684)
0.7 3.4 GO:0015840 urea transport(GO:0015840)
0.7 2.0 GO:0042351 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.7 3.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.6 5.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.6 4.5 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.6 3.2 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
0.6 2.6 GO:0021564 vagus nerve development(GO:0021564)
0.6 3.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.6 6.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.6 16.8 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.6 4.8 GO:0010265 SCF complex assembly(GO:0010265)
0.6 11.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.6 41.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.6 17.0 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.6 2.9 GO:0051693 actin filament capping(GO:0051693)
0.6 2.3 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.6 5.7 GO:0006974 cellular response to DNA damage stimulus(GO:0006974)
0.6 11.4 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.6 5.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.6 4.6 GO:0050747 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.6 1.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.6 5.1 GO:0051451 myoblast migration(GO:0051451)
0.6 13.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.6 7.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.6 15.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.5 2.7 GO:0060356 leucine import(GO:0060356)
0.5 40.1 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.5 2.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.5 10.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.5 7.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.5 6.7 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.5 9.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.5 5.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.5 13.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.5 13.1 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.5 6.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.5 4.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.5 12.2 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.5 1.5 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923)
0.5 1.5 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.5 2.4 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.5 1.9 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.5 1.0 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.5 4.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.5 10.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.5 5.2 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.5 1.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.5 8.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.5 26.0 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.5 1.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.4 41.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.4 34.0 GO:0070527 platelet aggregation(GO:0070527)
0.4 3.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 15.0 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.4 12.8 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.4 8.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.4 1.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.4 7.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 14.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 22.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.4 2.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.4 17.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 5.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.4 25.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 1.3 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.4 0.8 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.4 13.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.4 2.8 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.4 1.2 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.4 2.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.4 2.4 GO:0030421 defecation(GO:0030421)
0.4 15.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.4 1.6 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.4 2.3 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.4 9.0 GO:0000732 strand displacement(GO:0000732)
0.4 0.8 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.4 17.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.4 1.5 GO:0006740 NADPH regeneration(GO:0006740)
0.4 1.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.4 1.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.4 1.1 GO:1901656 glycoside transport(GO:1901656)
0.4 16.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.4 1.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.4 1.1 GO:0051685 maintenance of ER location(GO:0051685)
0.4 16.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.4 6.1 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.4 1.8 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.4 0.7 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.3 1.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 10.3 GO:0002576 platelet degranulation(GO:0002576)
0.3 1.4 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.3 1.7 GO:0070383 DNA cytosine deamination(GO:0070383)
0.3 5.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 35.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.3 5.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.3 8.2 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 3.6 GO:0006611 protein export from nucleus(GO:0006611)
0.3 9.1 GO:0030224 monocyte differentiation(GO:0030224)
0.3 5.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 15.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.3 5.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3 1.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.3 7.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.3 1.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 3.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 1.2 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.3 5.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.3 0.9 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.3 3.0 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.3 1.8 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 3.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.3 4.7 GO:0051014 actin filament severing(GO:0051014)
0.3 3.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 1.7 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.3 15.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 1.9 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 7.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 4.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.3 5.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 1.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 0.8 GO:0071724 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.3 1.8 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 30.8 GO:0006302 double-strand break repair(GO:0006302)
0.3 4.1 GO:0032060 bleb assembly(GO:0032060)
0.3 5.7 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.3 1.5 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 3.1 GO:0036258 multivesicular body organization(GO:0036257) multivesicular body assembly(GO:0036258)
0.3 6.4 GO:0090383 phagosome acidification(GO:0090383)
0.3 5.8 GO:0014904 myotube cell development(GO:0014904)
0.3 3.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.3 2.0 GO:0045059 positive thymic T cell selection(GO:0045059)
0.2 10.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 4.7 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.2 6.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.2 1.7 GO:0044346 fibroblast apoptotic process(GO:0044346) regulation of fibroblast apoptotic process(GO:2000269) positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 5.2 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.2 3.4 GO:0006105 succinate metabolic process(GO:0006105)
0.2 8.3 GO:0032570 response to progesterone(GO:0032570)
0.2 0.7 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.2 7.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2 2.8 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 2.1 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.2 0.5 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.2 1.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 1.6 GO:0060536 cartilage morphogenesis(GO:0060536)
0.2 1.1 GO:0031648 protein destabilization(GO:0031648)
0.2 2.1 GO:0006552 leucine catabolic process(GO:0006552)
0.2 2.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 1.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2 6.5 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.2 2.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 1.3 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.2 3.7 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.2 3.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.2 9.9 GO:0006414 translational elongation(GO:0006414)
0.2 9.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 4.3 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.2 12.8 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.2 2.6 GO:0036475 neuron death in response to oxidative stress(GO:0036475) regulation of oxidative stress-induced neuron death(GO:1903203) negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.2 19.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.2 1.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 55.7 GO:0008380 RNA splicing(GO:0008380)
0.2 1.9 GO:0015871 choline transport(GO:0015871)
0.2 0.4 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.2 5.0 GO:0010761 fibroblast migration(GO:0010761)
0.2 6.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 18.1 GO:0070268 cornification(GO:0070268)
0.2 0.2 GO:2000192 negative regulation of icosanoid secretion(GO:0032304) negative regulation of fatty acid transport(GO:2000192)
0.2 6.3 GO:0035329 hippo signaling(GO:0035329)
0.2 1.2 GO:1903209 positive regulation of oxidative stress-induced cell death(GO:1903209)
0.2 7.9 GO:0046324 regulation of glucose import(GO:0046324)
0.2 4.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 3.6 GO:0051972 regulation of telomerase activity(GO:0051972)
0.2 1.4 GO:0015693 magnesium ion transport(GO:0015693)
0.2 2.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 1.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 3.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2 1.9 GO:0031214 biomineral tissue development(GO:0031214)
0.2 11.2 GO:0051225 spindle assembly(GO:0051225)
0.2 2.2 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 0.8 GO:0022900 electron transport chain(GO:0022900)
0.2 1.3 GO:0097190 apoptotic signaling pathway(GO:0097190)
0.2 0.5 GO:0002818 intracellular defense response(GO:0002818)
0.2 1.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 1.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 2.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.9 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.8 GO:0001782 B cell homeostasis(GO:0001782)
0.1 0.4 GO:0051801 cytolysis by symbiont of host cells(GO:0001897) hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 1.9 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.7 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 2.8 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 1.6 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.2 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1 1.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 1.6 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 1.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 3.4 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.1 5.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.7 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 1.0 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 1.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 2.0 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 0.4 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 1.4 GO:0007567 parturition(GO:0007567)
0.1 1.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.3 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.1 1.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.6 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.5 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.1 0.5 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.1 0.8 GO:0000075 cell cycle checkpoint(GO:0000075)
0.1 4.3 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.3 GO:2001189 negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.1 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 6.3 GO:0002062 chondrocyte differentiation(GO:0002062)
0.1 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.9 GO:0010458 exit from mitosis(GO:0010458)
0.1 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.5 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.7 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.3 GO:0015691 cadmium ion transport(GO:0015691) lead ion transport(GO:0015692) cadmium ion transmembrane transport(GO:0070574)
0.1 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.1 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.7 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.6 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.3 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.0 4.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.5 GO:0030728 ovulation(GO:0030728)
0.0 0.9 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.8 GO:0051604 protein maturation(GO:0051604)
0.0 2.9 GO:0051170 nuclear import(GO:0051170)
0.0 3.5 GO:0006260 DNA replication(GO:0006260)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.6 GO:0030282 bone mineralization(GO:0030282)
0.0 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.0 9.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
7.5 30.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
7.4 51.7 GO:0005787 signal peptidase complex(GO:0005787)
5.9 29.6 GO:0097149 centralspindlin complex(GO:0097149)
5.0 25.2 GO:1990425 ryanodine receptor complex(GO:1990425)
4.8 24.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
4.8 33.3 GO:0044326 dendritic spine neck(GO:0044326)
4.7 14.0 GO:0033565 ESCRT-0 complex(GO:0033565)
4.6 55.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
4.6 73.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
4.6 13.7 GO:0071159 NF-kappaB complex(GO:0071159)
4.5 13.4 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
4.3 38.6 GO:0005638 lamin filament(GO:0005638)
4.2 12.7 GO:0044393 microspike(GO:0044393)
4.1 16.3 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
4.0 24.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
3.8 42.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
3.8 33.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
3.4 51.0 GO:0008290 F-actin capping protein complex(GO:0008290)
3.3 16.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
3.2 25.9 GO:0005610 laminin-5 complex(GO:0005610)
2.9 52.3 GO:0097342 ripoptosome(GO:0097342)
2.6 36.4 GO:0031209 SCAR complex(GO:0031209)
2.6 31.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
2.5 20.2 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
2.5 24.7 GO:0097255 R2TP complex(GO:0097255)
2.5 2.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
2.4 14.7 GO:0070761 pre-snoRNP complex(GO:0070761)
2.4 17.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
2.4 29.1 GO:0031595 nuclear proteasome complex(GO:0031595)
2.4 7.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
2.4 14.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
2.2 24.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
2.2 19.8 GO:0070652 HAUS complex(GO:0070652)
2.2 8.7 GO:0030896 checkpoint clamp complex(GO:0030896)
2.2 28.2 GO:0097433 dense body(GO:0097433)
2.1 10.6 GO:0043564 Ku70:Ku80 complex(GO:0043564)
2.0 43.0 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
2.0 8.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
1.9 15.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
1.9 11.3 GO:0071817 MMXD complex(GO:0071817)
1.9 9.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
1.8 33.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.8 12.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.8 21.5 GO:0005915 zonula adherens(GO:0005915)
1.8 10.7 GO:1990357 terminal web(GO:1990357)
1.8 7.1 GO:0005726 perichromatin fibrils(GO:0005726)
1.7 13.9 GO:0034719 SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
1.7 6.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.7 13.8 GO:0032133 chromosome passenger complex(GO:0032133)
1.7 6.9 GO:0032449 CBM complex(GO:0032449)
1.7 9.9 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
1.6 4.9 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.6 12.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
1.6 6.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.5 6.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
1.5 6.0 GO:0000811 GINS complex(GO:0000811)
1.3 10.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.3 10.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
1.3 14.3 GO:0071438 invadopodium membrane(GO:0071438)
1.3 6.4 GO:0000125 PCAF complex(GO:0000125)
1.3 3.8 GO:0031415 NatA complex(GO:0031415)
1.3 6.3 GO:0044530 supraspliceosomal complex(GO:0044530)
1.3 7.6 GO:1904724 tertiary granule lumen(GO:1904724)
1.2 19.7 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.2 3.6 GO:0034455 t-UTP complex(GO:0034455)
1.2 14.0 GO:0033093 Weibel-Palade body(GO:0033093)
1.1 11.4 GO:0000796 condensin complex(GO:0000796)
1.1 21.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
1.1 20.7 GO:0036020 endolysosome membrane(GO:0036020)
1.1 7.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
1.1 7.6 GO:0061617 MICOS complex(GO:0061617)
1.1 59.8 GO:0016235 aggresome(GO:0016235)
1.0 27.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.0 7.1 GO:0000812 Swr1 complex(GO:0000812)
1.0 6.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
1.0 7.8 GO:0033391 chromatoid body(GO:0033391)
1.0 3.9 GO:0032010 phagolysosome(GO:0032010)
1.0 36.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.0 15.3 GO:0071437 invadopodium(GO:0071437)
1.0 17.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.9 8.4 GO:0044754 autolysosome(GO:0044754)
0.9 4.6 GO:0030891 VCB complex(GO:0030891)
0.9 3.6 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.9 16.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.9 13.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.9 3.5 GO:0005687 U4 snRNP(GO:0005687)
0.9 15.6 GO:0031932 TORC2 complex(GO:0031932)
0.9 12.0 GO:0017119 Golgi transport complex(GO:0017119)
0.9 3.4 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.9 85.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.8 25.8 GO:0030057 desmosome(GO:0030057)
0.8 7.5 GO:0097413 Lewy body(GO:0097413)
0.8 9.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.8 20.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.8 12.1 GO:0001741 XY body(GO:0001741)
0.8 8.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.8 4.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.8 2.3 GO:0031982 vesicle(GO:0031982)
0.8 9.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.8 4.6 GO:0031526 brush border membrane(GO:0031526)
0.8 21.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.7 7.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.7 79.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.7 122.2 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.7 5.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.7 14.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.7 12.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.7 17.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.7 11.3 GO:0043231 intracellular membrane-bounded organelle(GO:0043231)
0.7 19.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.7 20.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.7 4.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.7 21.0 GO:0042101 T cell receptor complex(GO:0042101)
0.6 7.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.6 2.6 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.6 2.6 GO:1990075 periciliary membrane compartment(GO:1990075)
0.6 9.5 GO:0005686 U2 snRNP(GO:0005686)
0.6 28.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.6 73.3 GO:0005840 ribosome(GO:0005840)
0.6 18.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.6 4.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.6 12.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.6 7.7 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.6 33.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.6 6.6 GO:0005577 fibrinogen complex(GO:0005577)
0.5 5.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.5 13.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.5 1.6 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.5 5.2 GO:0010369 chromocenter(GO:0010369)
0.5 1.0 GO:0031528 microvillus membrane(GO:0031528)
0.5 4.6 GO:0061574 ASAP complex(GO:0061574)
0.5 17.1 GO:0032420 stereocilium(GO:0032420)
0.5 62.9 GO:0016605 PML body(GO:0016605)
0.5 2.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.5 3.4 GO:0005652 nuclear lamina(GO:0005652)
0.5 1.0 GO:0042627 chylomicron(GO:0042627)
0.5 8.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 1.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 1.3 GO:0036398 TCR signalosome(GO:0036398)
0.4 3.0 GO:0015629 actin cytoskeleton(GO:0015629)
0.4 15.9 GO:0016592 mediator complex(GO:0016592)
0.4 21.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.4 1.7 GO:0035838 growing cell tip(GO:0035838)
0.4 5.8 GO:0008091 spectrin(GO:0008091)
0.4 2.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.4 21.9 GO:0035580 specific granule lumen(GO:0035580)
0.4 1.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.4 20.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.4 37.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.4 1.6 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.4 2.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 0.8 GO:0001940 male pronucleus(GO:0001940)
0.4 5.0 GO:0000815 ESCRT III complex(GO:0000815)
0.4 4.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.4 1.1 GO:0005607 laminin-2 complex(GO:0005607)
0.4 3.7 GO:0001891 phagocytic cup(GO:0001891)
0.4 2.6 GO:0005614 interstitial matrix(GO:0005614)
0.4 6.5 GO:0009925 basal plasma membrane(GO:0009925)
0.4 42.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.4 1.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.4 1.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 14.9 GO:0005876 spindle microtubule(GO:0005876)
0.3 2.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.3 3.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.3 27.3 GO:0034707 chloride channel complex(GO:0034707)
0.3 16.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.3 1.0 GO:1990023 mitotic spindle midzone(GO:1990023)
0.3 14.8 GO:0005681 spliceosomal complex(GO:0005681)
0.3 1.2 GO:0042587 glycogen granule(GO:0042587)
0.3 4.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.3 6.5 GO:0031105 septin complex(GO:0031105)
0.3 4.2 GO:0032433 filopodium tip(GO:0032433)
0.3 21.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.3 4.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.3 5.0 GO:0031045 dense core granule(GO:0031045)
0.3 17.0 GO:0000792 heterochromatin(GO:0000792)
0.3 8.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.3 13.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 0.7 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2 1.5 GO:0032807 DNA ligase IV complex(GO:0032807)
0.2 10.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 27.2 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 35.9 GO:0000793 condensed chromosome(GO:0000793)
0.2 129.0 GO:0016604 nuclear body(GO:0016604)
0.2 4.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 1.8 GO:0035976 AP1 complex(GO:0035976)
0.2 4.9 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 23.1 GO:0034399 nuclear periphery(GO:0034399)
0.2 2.1 GO:0070069 cytochrome complex(GO:0070069)
0.2 1.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 1.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.2 7.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.2 0.7 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.2 98.2 GO:0070161 anchoring junction(GO:0070161)
0.2 10.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 0.7 GO:0005869 dynactin complex(GO:0005869)
0.2 8.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 4.1 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 10.1 GO:0042734 presynaptic membrane(GO:0042734)
0.2 0.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.2 12.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 10.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 11.3 GO:0005604 basement membrane(GO:0005604)
0.1 1.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 3.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 33.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 4.4 GO:0042581 specific granule(GO:0042581)
0.1 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 2.9 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 3.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 2.4 GO:0098800 inner mitochondrial membrane protein complex(GO:0098800)
0.1 5.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 18.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 11.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.9 GO:0030425 dendrite(GO:0030425)
0.0 0.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.4 GO:0005694 chromosome(GO:0005694)
0.0 51.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.1 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.0 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
16.8 50.5 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
13.5 40.6 GO:0050613 delta14-sterol reductase activity(GO:0050613)
8.5 33.9 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
8.4 25.2 GO:0008859 exoribonuclease II activity(GO:0008859)
7.7 46.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
7.5 22.6 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
7.5 30.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
6.8 27.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
6.7 26.8 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
6.6 19.9 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
5.2 15.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
5.1 20.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
4.6 41.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
4.5 13.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
4.4 21.8 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
4.2 25.3 GO:0047115 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
4.2 12.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
4.0 27.8 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
3.7 22.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
3.5 10.6 GO:0070538 oleic acid binding(GO:0070538)
3.5 10.4 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
3.4 13.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
3.4 13.4 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
3.2 25.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
3.2 9.7 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
3.1 18.8 GO:1990254 keratin filament binding(GO:1990254)
3.0 21.3 GO:0048408 epidermal growth factor binding(GO:0048408)
3.0 15.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
3.0 104.8 GO:0001848 complement binding(GO:0001848)
2.9 14.4 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
2.8 82.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
2.8 8.5 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
2.8 11.3 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
2.7 21.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
2.6 15.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
2.6 10.4 GO:0032395 MHC class II receptor activity(GO:0032395)
2.5 12.7 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
2.5 10.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.4 7.3 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
2.4 7.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
2.4 19.0 GO:0019863 IgE binding(GO:0019863)
2.3 9.2 GO:0004743 pyruvate kinase activity(GO:0004743)
2.3 9.1 GO:0016936 galactoside binding(GO:0016936)
2.3 13.7 GO:0070087 chromo shadow domain binding(GO:0070087)
2.3 9.1 GO:0043515 kinetochore binding(GO:0043515)
2.2 10.9 GO:0004906 interferon-gamma receptor activity(GO:0004906)
2.1 83.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
2.1 66.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
2.1 8.5 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
2.1 10.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
2.0 6.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
2.0 6.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
2.0 11.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
2.0 9.8 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
2.0 13.7 GO:0071532 ankyrin repeat binding(GO:0071532)
2.0 7.8 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.8 7.1 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
1.8 17.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.7 12.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
1.7 5.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
1.7 12.1 GO:0004673 protein histidine kinase activity(GO:0004673)
1.7 5.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
1.7 50.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.7 18.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.7 39.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
1.7 31.4 GO:0044548 S100 protein binding(GO:0044548)
1.7 6.6 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
1.6 8.2 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
1.6 13.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.6 25.7 GO:0050786 RAGE receptor binding(GO:0050786)
1.6 6.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.6 4.7 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
1.5 26.2 GO:0008494 translation activator activity(GO:0008494)
1.5 12.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.5 9.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.5 13.8 GO:0035174 histone serine kinase activity(GO:0035174)
1.5 4.6 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.5 4.6 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.5 4.4 GO:0033149 FFAT motif binding(GO:0033149)
1.4 4.3 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
1.4 7.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
1.4 10.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.4 16.8 GO:0031386 protein tag(GO:0031386)
1.4 4.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.4 20.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
1.4 8.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.3 4.0 GO:0031177 phosphopantetheine binding(GO:0031177)
1.3 18.4 GO:0035197 siRNA binding(GO:0035197)
1.3 22.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
1.3 12.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.3 6.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.3 12.6 GO:0042731 PH domain binding(GO:0042731)
1.3 288.7 GO:0003823 antigen binding(GO:0003823)
1.2 4.6 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.1 3.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
1.1 3.4 GO:0032427 GBD domain binding(GO:0032427)
1.1 11.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.0 14.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.0 6.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.0 6.1 GO:0070513 death domain binding(GO:0070513)
1.0 5.0 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
1.0 29.4 GO:0070717 poly-purine tract binding(GO:0070717)
1.0 3.9 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
1.0 6.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.0 7.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.0 5.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.9 7.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.9 8.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.9 2.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.9 18.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.9 8.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.9 16.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.9 9.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.9 2.7 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.9 4.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.9 2.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.9 6.0 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.8 21.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.8 3.2 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.8 7.2 GO:0043426 MRF binding(GO:0043426)
0.8 12.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.8 4.0 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.8 2.4 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.8 25.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.8 36.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.8 3.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.8 6.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.8 15.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.8 2.3 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.8 3.1 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.8 7.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.8 6.1 GO:0008565 protein transporter activity(GO:0008565)
0.8 59.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.7 4.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.7 9.7 GO:0043022 ribosome binding(GO:0043022)
0.7 12.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.7 11.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.7 2.9 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.7 6.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.7 2.8 GO:0004461 lactose synthase activity(GO:0004461)
0.7 13.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.7 22.6 GO:0070064 proline-rich region binding(GO:0070064)
0.7 7.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.7 5.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.7 4.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.7 19.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.7 4.0 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.7 11.9 GO:0043495 protein anchor(GO:0043495)
0.7 23.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.6 33.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.6 7.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.6 138.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.6 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.6 3.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.6 9.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6 16.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.6 27.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.6 3.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.6 6.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6 5.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.6 41.1 GO:0050681 androgen receptor binding(GO:0050681)
0.6 2.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.6 1.7 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.6 2.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.5 8.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5 6.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.5 2.1 GO:0046870 cadmium ion binding(GO:0046870)
0.5 17.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 2.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.5 57.5 GO:0002020 protease binding(GO:0002020)
0.5 8.1 GO:0051400 BH domain binding(GO:0051400)
0.5 13.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 3.5 GO:0030621 U4 snRNA binding(GO:0030621)
0.5 7.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.5 1.5 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.5 11.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.5 7.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.5 7.9 GO:0048018 receptor agonist activity(GO:0048018)
0.5 4.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.5 4.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.5 17.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.4 3.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 6.2 GO:0008432 JUN kinase binding(GO:0008432)
0.4 16.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 17.3 GO:0000049 tRNA binding(GO:0000049)
0.4 2.6 GO:0039552 RIG-I binding(GO:0039552)
0.4 13.8 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.4 1.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.4 3.8 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.4 3.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4 25.6 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.4 6.3 GO:0019843 rRNA binding(GO:0019843)
0.4 3.3 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 2.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.4 6.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 1.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 8.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 4.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 5.6 GO:0033691 sialic acid binding(GO:0033691)
0.4 6.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.4 2.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.4 16.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.4 10.0 GO:0031489 myosin V binding(GO:0031489)
0.4 1.9 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.4 3.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 4.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 10.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 1.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 5.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 4.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.4 33.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 18.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.3 1.4 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.3 1.7 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.3 1.3 GO:0017040 ceramidase activity(GO:0017040)
0.3 14.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.3 5.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 3.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 15.4 GO:0031491 nucleosome binding(GO:0031491)
0.3 1.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 0.9 GO:0003883 CTP synthase activity(GO:0003883)
0.3 0.9 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3 7.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.3 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.3 4.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 15.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 5.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 2.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 6.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.3 7.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 5.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.3 1.4 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.3 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.3 7.0 GO:0030506 ankyrin binding(GO:0030506)
0.3 10.2 GO:0042169 SH2 domain binding(GO:0042169)
0.3 0.8 GO:0001847 opsonin receptor activity(GO:0001847) peptidoglycan receptor activity(GO:0016019)
0.3 1.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.3 5.9 GO:0008198 ferrous iron binding(GO:0008198)
0.3 14.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 3.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 38.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 12.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 0.7 GO:0048030 disaccharide binding(GO:0048030)
0.2 1.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.2 1.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 1.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 1.9 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 7.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 6.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 0.8 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 2.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.2 6.3 GO:0002039 p53 binding(GO:0002039)
0.2 1.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 3.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 4.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 15.5 GO:0003777 microtubule motor activity(GO:0003777)
0.2 1.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 4.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 2.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.2 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 0.9 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 5.3 GO:0032451 demethylase activity(GO:0032451)
0.2 3.6 GO:0030515 snoRNA binding(GO:0030515)
0.2 2.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 0.5 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2 2.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 1.5 GO:0043566 structure-specific DNA binding(GO:0043566)
0.2 32.9 GO:0051015 actin filament binding(GO:0051015)
0.2 20.8 GO:0005178 integrin binding(GO:0005178)
0.2 9.1 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.2 5.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 2.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 5.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 2.6 GO:0030332 cyclin binding(GO:0030332)
0.1 0.9 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 6.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.4 GO:0017129 triglyceride binding(GO:0017129)
0.1 1.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 1.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 2.3 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.1 4.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 3.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 7.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 4.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 36.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 1.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 1.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 12.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.5 GO:1990459 transferrin receptor binding(GO:1990459) leptin receptor binding(GO:1990460)
0.1 0.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.7 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 6.1 GO:0019003 GDP binding(GO:0019003)
0.1 0.9 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 11.8 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.1 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 3.0 GO:0019894 kinesin binding(GO:0019894)
0.1 1.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.2 GO:0031996 thioesterase binding(GO:0031996)
0.1 2.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 1.9 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 3.2 GO:0004386 helicase activity(GO:0004386)
0.1 3.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.0 GO:0043621 protein self-association(GO:0043621)
0.1 2.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.5 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 11.4 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 2.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.3 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.1 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 6.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0016836 carbon-oxygen lyase activity(GO:0016835) hydro-lyase activity(GO:0016836)
0.0 5.3 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.1 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 3.4 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 50.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
1.6 3.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
1.4 2.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
1.3 69.2 PID CD40 PATHWAY CD40/CD40L signaling
1.3 25.2 PID ALK2 PATHWAY ALK2 signaling events
1.3 33.9 PID ALK1 PATHWAY ALK1 signaling events
1.2 31.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
1.1 39.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
1.1 25.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.1 51.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.9 68.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.9 12.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.9 116.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.8 19.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.8 46.0 PID AURORA B PATHWAY Aurora B signaling
0.8 23.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.8 25.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.7 25.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.7 28.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.6 34.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.6 20.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.6 12.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.6 9.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.6 15.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.6 21.4 PID BARD1 PATHWAY BARD1 signaling events
0.6 2.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.5 27.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.5 7.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.5 41.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.5 18.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.5 14.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.5 8.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.5 12.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.5 9.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.5 36.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.5 17.3 PID RAS PATHWAY Regulation of Ras family activation
0.5 6.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.5 20.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.4 21.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.4 21.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.4 23.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 8.8 PID ARF 3PATHWAY Arf1 pathway
0.4 27.1 PID E2F PATHWAY E2F transcription factor network
0.4 7.9 PID TNF PATHWAY TNF receptor signaling pathway
0.4 12.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.4 1.8 ST STAT3 PATHWAY STAT3 Pathway
0.3 11.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.3 4.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 8.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 11.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.3 18.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.3 14.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 2.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 4.9 PID FOXO PATHWAY FoxO family signaling
0.2 1.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 11.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 3.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 5.5 PID PLK1 PATHWAY PLK1 signaling events
0.1 14.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 5.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.0 PID ENDOTHELIN PATHWAY Endothelins
0.1 7.9 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 3.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.7 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID ATM PATHWAY ATM pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.5 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
3.0 27.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
2.9 11.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
2.9 48.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
2.4 80.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
2.2 52.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
2.1 23.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.9 57.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.8 32.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
1.8 139.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
1.7 50.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.7 24.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.7 33.9 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
1.6 55.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.6 11.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
1.6 31.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.5 18.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.5 40.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.3 20.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
1.3 48.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
1.3 20.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.2 26.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.1 29.3 REACTOME KINESINS Genes involved in Kinesins
1.1 29.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.1 22.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.0 22.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
1.0 27.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.9 10.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.9 13.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.9 22.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.9 20.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.9 27.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.8 13.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.8 25.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.8 31.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.8 13.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.8 13.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.8 18.6 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.8 7.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.8 35.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.8 6.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.7 24.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.7 16.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.7 4.7 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.7 13.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.7 21.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.6 18.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.6 51.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.6 6.0 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.6 7.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.6 10.6 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.6 101.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.6 6.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.6 16.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.6 11.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.6 9.9 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.5 42.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.5 12.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.5 11.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 12.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.5 59.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.5 6.5 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.5 9.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.5 8.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.5 22.9 REACTOME TRANSLATION Genes involved in Translation
0.5 12.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.4 7.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.4 9.6 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.4 14.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.4 4.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 54.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.4 19.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.4 15.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.4 5.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.4 20.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.4 6.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 46.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.4 6.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 4.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.4 8.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.3 2.8 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.3 3.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 2.1 REACTOME HEMOSTASIS Genes involved in Hemostasis
0.3 4.8 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.3 10.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.3 6.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.3 7.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 5.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 22.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 7.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.3 5.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3 11.3 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.3 17.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 9.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 5.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.3 9.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.3 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 5.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 7.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 6.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 6.5 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.2 2.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 10.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 3.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 13.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 1.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 5.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 10.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 0.4 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 2.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 4.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 12.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 1.0 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 4.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 2.5 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.2 3.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 8.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 5.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 4.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 7.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 3.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.6 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.5 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 3.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway