averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
CEBPE Links Ensembl NCBI GeneCards UniProt	ENSG00000092067.5	CCAAT enhancer binding protein epsilon
CEBPD Links Ensembl NCBI GeneCards UniProt	ENSG00000221869.4	CCAAT enhancer binding protein delta

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CEBPD	hg19_v2_chr8_-_48651648_48651648	0.61	1.9e-23	Click!
CEBPE	hg19_v2_chr14_-_23588816_23588836	0.07	3.2e-01	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_+_7167980 Show fit	26.84	ENST00000360817.5 ENST00000402681.3	C1S Links Ensembl NCBI GeneCards UniProt Show fit	complement component 1, s subcomponent
chr19_-_6720686 Show fit	24.81	ENST00000245907.6	C3 Links Ensembl NCBI GeneCards UniProt Show fit	complement component 3
chr9_-_94186131 Show fit	24.43	ENST00000297689.3	NFIL3 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor, interleukin 3 regulated
chr4_-_185747188 Show fit	16.44	ENST00000507295.1 ENST00000504900.1 ENST00000281455.2 ENST00000454703.2	ACSL1 Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long-chain family member 1
chr14_-_23285069 Show fit	16.41	ENST00000554758.1 ENST00000397528.4	SLC7A7 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_-_23285011 Show fit	16.20	ENST00000397532.3	SLC7A7 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr5_+_49963239 Show fit	15.96	ENST00000505554.1	PARP8 Links Ensembl NCBI GeneCards UniProt Show fit	poly (ADP-ribose) polymerase family, member 8
chr12_-_91573132 Show fit	15.62	ENST00000550563.1 ENST00000546370.1	DCN Links Ensembl NCBI GeneCards UniProt Show fit	decorin
chr19_-_40971667 Show fit	15.45	ENST00000263368.4	BLVRB Links Ensembl NCBI GeneCards UniProt Show fit	biliverdin reductase B (flavin reductase (NADPH))
chr15_+_45926919 Show fit	15.43	ENST00000561735.1 ENST00000260324.7	SQRDL Links Ensembl NCBI GeneCards UniProt Show fit	sulfide quinone reductase-like (yeast)
chr12_-_91573249 Show fit	15.06	ENST00000550099.1 ENST00000546391.1 ENST00000551354.1	DCN Links Ensembl NCBI GeneCards UniProt Show fit	decorin
chr10_+_17270214 Show fit	14.27	ENST00000544301.1	VIM Links Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr19_-_40971643 Show fit	14.09	ENST00000595483.1	BLVRB Links Ensembl NCBI GeneCards UniProt Show fit	biliverdin reductase B (flavin reductase (NADPH))
chr12_-_96390063 Show fit	13.87	ENST00000541929.1	HAL Links Ensembl NCBI GeneCards UniProt Show fit	histidine ammonia-lyase
chr3_+_186330712 Show fit	13.68	ENST00000411641.2 ENST00000273784.5	AHSG Links Ensembl NCBI GeneCards UniProt Show fit	alpha-2-HS-glycoprotein
chr15_+_58430368 Show fit	13.46	ENST00000558772.1 ENST00000219919.4	AQP9 Links Ensembl NCBI GeneCards UniProt Show fit	aquaporin 9
chr12_-_123201337 Show fit	13.12	ENST00000528880.2	HCAR3 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxycarboxylic acid receptor 3
chr2_+_102721023 Show fit	12.74	ENST00000409589.1 ENST00000409329.1	IL1R1 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor, type I
chr8_-_134309823 Show fit	12.02	ENST00000414097.2	NDRG1 Links Ensembl NCBI GeneCards UniProt Show fit	N-myc downstream regulated 1
chr15_+_58430567 Show fit	12.02	ENST00000536493.1	AQP9 Links Ensembl NCBI GeneCards UniProt Show fit	aquaporin 9
chr3_+_157154578 Show fit	11.69	ENST00000295927.3	PTX3 Links Ensembl NCBI GeneCards UniProt Show fit	pentraxin 3, long
chr12_-_123187890 Show fit	11.63	ENST00000328880.5	HCAR2 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxycarboxylic acid receptor 2
chr6_-_133055815 Show fit	10.93	ENST00000509351.1 ENST00000417437.2 ENST00000414302.2 ENST00000423615.2 ENST00000427187.2 ENST00000275223.3 ENST00000519686.2	VNN3 Links Ensembl NCBI GeneCards UniProt Show fit	vanin 3
chr5_+_95997918 Show fit	10.73	ENST00000395812.2 ENST00000395813.1 ENST00000359176.4 ENST00000325674.7	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr6_+_31895467 Show fit	10.67	ENST00000556679.1 ENST00000456570.1	CFB Links Ensembl NCBI GeneCards UniProt Show fit CFB Links Ensembl NCBI GeneCards UniProt Show fit	complement factor B Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr5_-_140013275 Show fit	10.44	ENST00000512545.1 ENST00000302014.6 ENST00000401743.2	CD14 Links Ensembl NCBI GeneCards UniProt Show fit	CD14 molecule
chr2_+_219247021 Show fit	10.36	ENST00000539932.1	SLC11A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr17_-_34625719 Show fit	10.35	ENST00000422211.2 ENST00000542124.1	CCL3L1 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 3-like 1
chr2_-_216300784 Show fit	10.11	ENST00000421182.1 ENST00000432072.2 ENST00000323926.6 ENST00000336916.4 ENST00000357867.4 ENST00000359671.1 ENST00000346544.3 ENST00000345488.5 ENST00000357009.2 ENST00000446046.1 ENST00000356005.4 ENST00000443816.1 ENST00000426059.1 ENST00000354785.4	FN1 Links Ensembl NCBI GeneCards UniProt Show fit	fibronectin 1
chr8_-_134309335 Show fit	9.87	ENST00000522890.1 ENST00000323851.7 ENST00000518176.1 ENST00000354944.5 ENST00000537882.1 ENST00000522476.1 ENST00000518066.1 ENST00000521544.1 ENST00000518480.1 ENST00000523892.1	NDRG1 Links Ensembl NCBI GeneCards UniProt Show fit	N-myc downstream regulated 1
chr17_-_34417479 Show fit	9.61	ENST00000225245.5	CCL3 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 3
chr6_-_133055896 Show fit	9.60	ENST00000367927.5 ENST00000425515.2 ENST00000207771.3 ENST00000392393.3 ENST00000450865.2 ENST00000392394.2	VNN3 Links Ensembl NCBI GeneCards UniProt Show fit	vanin 3
chr1_-_186649543 Show fit	9.44	ENST00000367468.5	PTGS2 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_6735451 Show fit	9.33	ENST00000297439.3	DEFB1 Links Ensembl NCBI GeneCards UniProt Show fit	defensin, beta 1
chr5_+_95998070 Show fit	9.24	ENST00000421689.2 ENST00000510756.1 ENST00000512620.1	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr16_+_72088376 Show fit	9.15	ENST00000570083.1 ENST00000355906.5 ENST00000398131.2 ENST00000569639.1 ENST00000564499.1 ENST00000357763.4 ENST00000562526.1 ENST00000565574.1 ENST00000568417.2 ENST00000356967.5	HP Links Ensembl NCBI GeneCards UniProt Show fit HPR Links Ensembl NCBI GeneCards UniProt Show fit	haptoglobin haptoglobin-related protein
chr16_-_84651647 Show fit	9.04	ENST00000564057.1	COTL1 Links Ensembl NCBI GeneCards UniProt Show fit	coactosin-like 1 (Dictyostelium)
chr17_+_7461849 Show fit	9.03	ENST00000338784.4	TNFSF13 Links Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor (ligand) superfamily, member 13
chr10_-_82049424 Show fit	8.97	ENST00000372213.3	MAT1A Links Ensembl NCBI GeneCards UniProt Show fit	methionine adenosyltransferase I, alpha
chr17_+_7461781 Show fit	8.95	ENST00000349228.4	TNFSF13 Links Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor (ligand) superfamily, member 13
chr17_+_7462103 Show fit	8.95	ENST00000396545.4	TNFSF13 Links Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor (ligand) superfamily, member 13
chr20_-_43883197 Show fit	8.73	ENST00000338380.2	SLPI Links Ensembl NCBI GeneCards UniProt Show fit	secretory leukocyte peptidase inhibitor
chr20_-_17662878 Show fit	8.49	ENST00000377813.1 ENST00000377807.2 ENST00000360807.4 ENST00000398782.2	RRBP1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosome binding protein 1
chr6_-_32557610 Show fit	8.26	ENST00000360004.5	HLA-DRB1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DR beta 1
chr19_+_859425 Show fit	8.23	ENST00000327726.6	CFD Links Ensembl NCBI GeneCards UniProt Show fit	complement factor D (adipsin)
chr4_+_55095264 Show fit	8.23	ENST00000257290.5	PDGFRA Links Ensembl NCBI GeneCards UniProt Show fit	platelet-derived growth factor receptor, alpha polypeptide
chr16_-_84651673 Show fit	8.22	ENST00000262428.4	COTL1 Links Ensembl NCBI GeneCards UniProt Show fit	coactosin-like 1 (Dictyostelium)
chr2_-_113594279 Show fit	8.14	ENST00000416750.1 ENST00000418817.1 ENST00000263341.2	IL1B Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1, beta
chr3_+_46395219 Show fit	8.04	ENST00000445132.2 ENST00000292301.4	CCR2 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) receptor 2
chr1_+_154377669 Show fit	7.84	ENST00000368485.3 ENST00000344086.4	IL6R Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 receptor
chr19_-_2042065 Show fit	7.82	ENST00000591588.1 ENST00000591142.1	MKNK2 Links Ensembl NCBI GeneCards UniProt Show fit	MAP kinase interacting serine/threonine kinase 2
chr17_-_34524157 Show fit	7.79	ENST00000378354.4 ENST00000394484.1	CCL3L3 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 3-like 3
chr12_-_96390108 Show fit	7.64	ENST00000538703.1 ENST00000261208.3	HAL Links Ensembl NCBI GeneCards UniProt Show fit	histidine ammonia-lyase
chr19_+_859654 Show fit	7.58	ENST00000592860.1	CFD Links Ensembl NCBI GeneCards UniProt Show fit	complement factor D (adipsin)
chr3_-_58200398 Show fit	7.58	ENST00000318316.3 ENST00000460422.1 ENST00000483681.1	DNASE1L3 Links Ensembl NCBI GeneCards UniProt Show fit	deoxyribonuclease I-like 3
chr6_+_31895480 Show fit	7.44	ENST00000418949.2 ENST00000383177.3 ENST00000477310.1	C2 Links Ensembl NCBI GeneCards UniProt Show fit CFB Links Ensembl NCBI GeneCards UniProt Show fit	complement component 2 Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr3_-_46506358 Show fit	7.34	ENST00000417439.1 ENST00000431944.1	LTF Links Ensembl NCBI GeneCards UniProt Show fit	lactotransferrin
chr6_+_31895254 Show fit	7.33	ENST00000299367.5 ENST00000442278.2	C2 Links Ensembl NCBI GeneCards UniProt Show fit	complement component 2
chr5_+_95997769 Show fit	7.20	ENST00000338252.3 ENST00000508830.1	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr17_+_7462031 Show fit	7.17	ENST00000380535.4	TNFSF13 Links Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor (ligand) superfamily, member 13
chr3_+_186435137 Show fit	7.14	ENST00000447445.1	KNG1 Links Ensembl NCBI GeneCards UniProt Show fit	kininogen 1
chr2_+_219246746 Show fit	7.04	ENST00000233202.6	SLC11A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr3_+_186383741 Show fit	6.95	ENST00000232003.4	HRG Links Ensembl NCBI GeneCards UniProt Show fit	histidine-rich glycoprotein
chr3_-_46506563 Show fit	6.92	ENST00000231751.4	LTF Links Ensembl NCBI GeneCards UniProt Show fit	lactotransferrin
chr12_+_102271129 Show fit	6.88	ENST00000258534.8	DRAM1 Links Ensembl NCBI GeneCards UniProt Show fit	DNA-damage regulated autophagy modulator 1
chr17_-_7017968 Show fit	6.74	ENST00000355035.5	ASGR2 Links Ensembl NCBI GeneCards UniProt Show fit	asialoglycoprotein receptor 2
chr16_-_21663919 Show fit	6.39	ENST00000569602.1	IGSF6 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily, member 6
chr19_+_6887571 Show fit	6.36	ENST00000250572.8 ENST00000381407.5 ENST00000312053.4 ENST00000450315.3 ENST00000381404.4	EMR1 Links Ensembl NCBI GeneCards UniProt Show fit	egf-like module containing, mucin-like, hormone receptor-like 1
chr3_-_158450475 Show fit	6.28	ENST00000237696.5	RARRES1 Links Ensembl NCBI GeneCards UniProt Show fit	retinoic acid receptor responder (tazarotene induced) 1
chr8_-_27468842 Show fit	6.27	ENST00000523500.1	CLU Links Ensembl NCBI GeneCards UniProt Show fit	clusterin
chr17_-_7018128 Show fit	6.15	ENST00000380952.2 ENST00000254850.7	ASGR2 Links Ensembl NCBI GeneCards UniProt Show fit	asialoglycoprotein receptor 2
chr12_-_91573316 Show fit	6.05	ENST00000393155.1	DCN Links Ensembl NCBI GeneCards UniProt Show fit	decorin
chr8_-_27468945 Show fit	6.00	ENST00000405140.3	CLU Links Ensembl NCBI GeneCards UniProt Show fit	clusterin
chr3_-_158450231 Show fit	5.96	ENST00000479756.1	RARRES1 Links Ensembl NCBI GeneCards UniProt Show fit	retinoic acid receptor responder (tazarotene induced) 1
chr3_+_186435065 Show fit	5.92	ENST00000287611.2 ENST00000265023.4	KNG1 Links Ensembl NCBI GeneCards UniProt Show fit	kininogen 1
chr5_+_49962772 Show fit	5.67	ENST00000281631.5 ENST00000513738.1 ENST00000503665.1 ENST00000514067.2 ENST00000503046.1	PARP8 Links Ensembl NCBI GeneCards UniProt Show fit	poly (ADP-ribose) polymerase family, member 8
chr8_+_12808834 Show fit	5.48	ENST00000400069.3	KIAA1456 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA1456
chr20_+_56136136 Show fit	5.15	ENST00000319441.4 ENST00000543666.1	PCK1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoenolpyruvate carboxykinase 1 (soluble)
chr7_-_36764004 Show fit	4.92	ENST00000431169.1	AOAH Links Ensembl NCBI GeneCards UniProt Show fit	acyloxyacyl hydrolase (neutrophil)
chr3_+_11314099 Show fit	4.54	ENST00000446450.2 ENST00000354956.5 ENST00000354449.3 ENST00000419112.1	ATG7 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 7
chr7_+_22766766 Show fit	4.47	ENST00000426291.1 ENST00000401651.1 ENST00000258743.5 ENST00000420258.2 ENST00000407492.1 ENST00000401630.3 ENST00000406575.1	IL6 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 (interferon, beta 2)
chr6_-_112194484 Show fit	4.45	ENST00000518295.1 ENST00000484067.2 ENST00000229470.5 ENST00000356013.2 ENST00000368678.4 ENST00000523238.1 ENST00000354650.3	FYN Links Ensembl NCBI GeneCards UniProt Show fit	FYN oncogene related to SRC, FGR, YES
chr16_-_21663950 Show fit	4.41	ENST00000268389.4	IGSF6 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily, member 6
chr8_-_27469196 Show fit	4.39	ENST00000546343.1 ENST00000560566.1	CLU Links Ensembl NCBI GeneCards UniProt Show fit	clusterin
chr13_-_46679185 Show fit	4.38	ENST00000439329.3	CPB2 Links Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase B2 (plasma)
chr11_-_18270182 Show fit	4.35	ENST00000528349.1 ENST00000526900.1 ENST00000529528.1 ENST00000414546.2 ENST00000256733.4	SAA2 Links Ensembl NCBI GeneCards UniProt Show fit	serum amyloid A2
chr13_-_46679144 Show fit	4.32	ENST00000181383.4	CPB2 Links Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase B2 (plasma)
chr11_+_18287801 Show fit	4.19	ENST00000532858.1 ENST00000405158.2	SAA1 Links Ensembl NCBI GeneCards UniProt Show fit	serum amyloid A1
chr11_+_18287721 Show fit	4.08	ENST00000356524.4	SAA1 Links Ensembl NCBI GeneCards UniProt Show fit	serum amyloid A1
chr6_+_1389989 Show fit	4.06	ENST00000259806.1	FOXF2 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box F2
chr11_+_33279850 Show fit	3.79	ENST00000531504.1 ENST00000456517.1	HIPK3 Links Ensembl NCBI GeneCards UniProt Show fit	homeodomain interacting protein kinase 3
chr17_+_20059302 Show fit	3.75	ENST00000395530.2	SPECC1 Links Ensembl NCBI GeneCards UniProt Show fit	sperm antigen with calponin homology and coiled-coil domains 1
chr15_+_39873268 Show fit	3.71	ENST00000397591.2 ENST00000260356.5	THBS1 Links Ensembl NCBI GeneCards UniProt Show fit	thrombospondin 1
chr9_+_33290491 Show fit	3.70	ENST00000379540.3 ENST00000379521.4 ENST00000318524.6	NFX1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear transcription factor, X-box binding 1
chr2_+_46769798 Show fit	3.69	ENST00000238738.4	RHOQ Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member Q
chr2_-_178128250 Show fit	3.65	ENST00000448782.1 ENST00000446151.2	NFE2L2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor, erythroid 2-like 2
chr3_-_99594948 Show fit	3.63	ENST00000471562.1 ENST00000495625.2	FILIP1L Links Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1-like
chr11_-_104972158 Show fit	3.61	ENST00000598974.1 ENST00000593315.1 ENST00000594519.1 ENST00000415981.2 ENST00000525374.1 ENST00000375707.1	CASP1 Links Ensembl NCBI GeneCards UniProt Show fit CARD16 Links Ensembl NCBI GeneCards UniProt Show fit CARD17 Links Ensembl NCBI GeneCards UniProt Show fit	caspase 1, apoptosis-related cysteine peptidase caspase recruitment domain family, member 16 caspase recruitment domain family, member 17
chr11_-_77185094 Show fit	3.61	ENST00000278568.4 ENST00000356341.3	PAK1 Links Ensembl NCBI GeneCards UniProt Show fit	p21 protein (Cdc42/Rac)-activated kinase 1
chrX_+_138612889 Show fit	3.56	ENST00000218099.2 ENST00000394090.2	F9 Links Ensembl NCBI GeneCards UniProt Show fit	coagulation factor IX
chr4_-_155511887 Show fit	3.55	ENST00000302053.3 ENST00000403106.3	FGA Links Ensembl NCBI GeneCards UniProt Show fit	fibrinogen alpha chain
chrY_+_2709527 Show fit	3.30	ENST00000250784.8	RPS4Y1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S4, Y-linked 1
chr14_+_58765103 Show fit	3.19	ENST00000355431.3 ENST00000348476.3 ENST00000395168.3	ARID4A Links Ensembl NCBI GeneCards UniProt Show fit	AT rich interactive domain 4A (RBP1-like)
chr13_-_29292956 Show fit	3.14	ENST00000266943.6	SLC46A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 46, member 3
chr1_+_209941827 Show fit	3.07	ENST00000367023.1	TRAF3IP3 Links Ensembl NCBI GeneCards UniProt Show fit	TRAF3 interacting protein 3
chr1_-_1711508 Show fit	3.06	ENST00000378625.1	NADK Links Ensembl NCBI GeneCards UniProt Show fit	NAD kinase
chr1_-_111743285 Show fit	3.04	ENST00000357640.4	DENND2D Links Ensembl NCBI GeneCards UniProt Show fit	DENN/MADD domain containing 2D
chr20_+_44098346 Show fit	3.03	ENST00000372676.3	WFDC2 Links Ensembl NCBI GeneCards UniProt Show fit	WAP four-disulfide core domain 2
chr3_+_133465228 Show fit	2.97	ENST00000482271.1 ENST00000264998.3	TF Links Ensembl NCBI GeneCards UniProt Show fit	transferrin
chr11_+_82868030 Show fit	2.91	ENST00000298281.4 ENST00000530660.1	PCF11 Links Ensembl NCBI GeneCards UniProt Show fit	PCF11 cleavage and polyadenylation factor subunit
chr1_+_82266053 Show fit	2.84	ENST00000370715.1 ENST00000370713.1 ENST00000319517.6 ENST00000370717.2 ENST00000394879.1 ENST00000271029.4 ENST00000335786.5	LPHN2 Links Ensembl NCBI GeneCards UniProt Show fit	latrophilin 2
chr14_+_21423611 Show fit	2.74	ENST00000304625.2	RNASE2 Links Ensembl NCBI GeneCards UniProt Show fit	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr1_+_209941942 Show fit	2.72	ENST00000487271.1 ENST00000477431.1	TRAF3IP3 Links Ensembl NCBI GeneCards UniProt Show fit	TRAF3 interacting protein 3
chr4_+_25657444 Show fit	2.68	ENST00000504570.1 ENST00000382051.3	SLC34A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 34 (type II sodium/phosphate contransporter), member 2
chr4_-_186732048 Show fit	2.68	ENST00000448662.2 ENST00000439049.1 ENST00000420158.1 ENST00000431808.1 ENST00000319471.9	SORBS2 Links Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr20_+_44098385 Show fit	2.67	ENST00000217425.5 ENST00000339946.3	WFDC2 Links Ensembl NCBI GeneCards UniProt Show fit	WAP four-disulfide core domain 2
chr6_-_24489842 Show fit	2.65	ENST00000230036.1	GPLD1 Links Ensembl NCBI GeneCards UniProt Show fit	glycosylphosphatidylinositol specific phospholipase D1
chr11_-_104905840 Show fit	2.62	ENST00000526568.1 ENST00000393136.4 ENST00000531166.1 ENST00000534497.1 ENST00000527979.1 ENST00000446369.1 ENST00000353247.5 ENST00000528974.1 ENST00000533400.1 ENST00000525825.1 ENST00000436863.3	CASP1 Links Ensembl NCBI GeneCards UniProt Show fit	caspase 1, apoptosis-related cysteine peptidase
chr3_-_99595037 Show fit	2.49	ENST00000383694.2	FILIP1L Links Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1-like
chr14_-_64971288 Show fit	2.48	ENST00000394715.1	ZBTB25 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 25
chr4_+_71263599 Show fit	2.41	ENST00000399575.2	PROL1 Links Ensembl NCBI GeneCards UniProt Show fit	proline rich, lacrimal 1
chr5_-_121413974 Show fit	2.37	ENST00000231004.4	LOX Links Ensembl NCBI GeneCards UniProt Show fit	lysyl oxidase
chr4_-_76928641 Show fit	2.27	ENST00000264888.5	CXCL9 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-X-C motif) ligand 9
chr12_+_66582919 Show fit	2.18	ENST00000545837.1 ENST00000457197.2	IRAK3 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin-1 receptor-associated kinase 3
chr19_-_41356347 Show fit	2.17	ENST00000301141.5	CYP2A6 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450, family 2, subfamily A, polypeptide 6
chr12_-_12491608 Show fit	2.16	ENST00000545735.1	MANSC1 Links Ensembl NCBI GeneCards UniProt Show fit	MANSC domain containing 1
chr5_-_10761206 Show fit	2.16	ENST00000432074.2 ENST00000230895.6	DAP Links Ensembl NCBI GeneCards UniProt Show fit	death-associated protein
chr19_-_52148798 Show fit	2.13	ENST00000534261.2	SIGLEC5 Links Ensembl NCBI GeneCards UniProt Show fit	sialic acid binding Ig-like lectin 5
chr20_-_1600642 Show fit	2.11	ENST00000381603.3 ENST00000381605.4 ENST00000279477.7 ENST00000568365.1 ENST00000564763.1	SIRPB1 Links Ensembl NCBI GeneCards UniProt Show fit RP4-576H24.4 Links Ensembl NCBI GeneCards UniProt Show fit	signal-regulatory protein beta 1 Uncharacterized protein
chr11_+_15095108 Show fit	2.07	ENST00000324229.6 ENST00000533448.1	CALCB Links Ensembl NCBI GeneCards UniProt Show fit	calcitonin-related polypeptide beta
chr19_-_41388657 Show fit	2.03	ENST00000301146.4 ENST00000291764.3	CYP2A7 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450, family 2, subfamily A, polypeptide 7
chr14_-_45722605 Show fit	1.97	ENST00000310806.4	MIS18BP1 Links Ensembl NCBI GeneCards UniProt Show fit	MIS18 binding protein 1
chr2_-_178128528 Show fit	1.96	ENST00000397063.4 ENST00000421929.1	NFE2L2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor, erythroid 2-like 2
chr5_+_134368954 Show fit	1.91	ENST00000432382.3	CTC-349C3.1 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 5 open reading frame 66
chr3_+_88188254 Show fit	1.88	ENST00000309495.5	ZNF654 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 654
chr9_-_99381660 Show fit	1.82	ENST00000375240.3 ENST00000463569.1	CDC14B Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14B
chr10_+_90750378 Show fit	1.72	ENST00000355740.2 ENST00000352159.4	FAS Links Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr6_+_108977520 Show fit	1.71	ENST00000540898.1	FOXO3 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box O3
chr19_+_11350278 Show fit	1.70	ENST00000252453.8	C19orf80 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 19 open reading frame 80
chr11_-_14993819 Show fit	1.65	ENST00000396372.2 ENST00000361010.3 ENST00000359642.3 ENST00000331587.4	CALCA Links Ensembl NCBI GeneCards UniProt Show fit	calcitonin-related polypeptide alpha
chr11_-_18258342 Show fit	1.63	ENST00000278222.4	SAA4 Links Ensembl NCBI GeneCards UniProt Show fit	serum amyloid A4, constitutive
chr2_-_191878874 Show fit	1.62	ENST00000392322.3 ENST00000392323.2 ENST00000424722.1 ENST00000361099.3	STAT1 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 1, 91kDa
chr1_-_151032040 Show fit	1.62	ENST00000540998.1 ENST00000357235.5	CDC42SE1 Links Ensembl NCBI GeneCards UniProt Show fit	CDC42 small effector 1
chr16_+_3507985 Show fit	1.60	ENST00000421765.3 ENST00000360862.5 ENST00000414063.2 ENST00000610180.1 ENST00000608993.1	NAA60 Links Ensembl NCBI GeneCards UniProt Show fit NAA60 Links Ensembl NCBI GeneCards UniProt Show fit	N(alpha)-acetyltransferase 60, NatF catalytic subunit N-alpha-acetyltransferase 60
chr10_+_90750493 Show fit	1.54	ENST00000357339.2 ENST00000355279.2	FAS Links Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr2_-_209118974 Show fit	1.51	ENST00000415913.1 ENST00000415282.1 ENST00000446179.1	IDH1 Links Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase 1 (NADP+), soluble
chrX_+_46937745 Show fit	1.50	ENST00000397180.1 ENST00000457380.1 ENST00000352078.4	RGN Links Ensembl NCBI GeneCards UniProt Show fit	regucalcin
chrX_+_24483338 Show fit	1.47	ENST00000379162.4 ENST00000441463.2	PDK3 Links Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehydrogenase kinase, isozyme 3
chr14_-_106573756 Show fit	1.47	ENST00000390601.2	IGHV3-11 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr1_-_168698433 Show fit	1.44	ENST00000367817.3	DPT Links Ensembl NCBI GeneCards UniProt Show fit	dermatopontin
chr6_-_31940065 Show fit	1.43	ENST00000375349.3 ENST00000337523.5	DXO Links Ensembl NCBI GeneCards UniProt Show fit	decapping exoribonuclease
chr20_-_22566089 Show fit	1.43	ENST00000377115.4	FOXA2 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box A2
chr4_+_96012614 Show fit	1.39	ENST00000264568.4	BMPR1B Links Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein receptor, type IB
chr20_-_34330129 Show fit	1.32	ENST00000397370.3 ENST00000528062.3 ENST00000407261.4 ENST00000374038.3 ENST00000361162.6	RBM39 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 39
chr3_-_148939835 Show fit	1.31	ENST00000264613.6	CP Links Ensembl NCBI GeneCards UniProt Show fit	ceruloplasmin (ferroxidase)
chr11_-_64510409 Show fit	1.28	ENST00000394429.1 ENST00000394428.1	RASGRP2 Links Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr21_+_27011584 Show fit	1.16	ENST00000400532.1 ENST00000480456.1 ENST00000312957.5	JAM2 Links Ensembl NCBI GeneCards UniProt Show fit	junctional adhesion molecule 2
chr19_+_41497178 Show fit	1.14	ENST00000324071.4	CYP2B6 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450, family 2, subfamily B, polypeptide 6
chr1_-_149832704 Show fit	1.13	ENST00000392933.1 ENST00000369157.2 ENST00000392932.4	HIST2H4B Links Ensembl NCBI GeneCards UniProt Show fit	histone cluster 2, H4b
chr4_+_78079450 Show fit	1.06	ENST00000395640.1 ENST00000512918.1	CCNG2 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin G2
chr4_+_78079570 Show fit	1.06	ENST00000509972.1	CCNG2 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin G2
chr1_-_228613026 Show fit	1.06	ENST00000366696.1	HIST3H3 Links Ensembl NCBI GeneCards UniProt Show fit	histone cluster 3, H3
chr1_+_245133278 Show fit	1.05	ENST00000366522.2	EFCAB2 Links Ensembl NCBI GeneCards UniProt Show fit	EF-hand calcium binding domain 2
chr18_+_21032781 Show fit	1.03	ENST00000339486.3	RIOK3 Links Ensembl NCBI GeneCards UniProt Show fit	RIO kinase 3
chr5_-_39364586 Show fit	1.00	ENST00000263408.4	C9 Links Ensembl NCBI GeneCards UniProt Show fit	complement component 9
chr1_-_45956822 Show fit	0.95	ENST00000372086.3 ENST00000341771.6	TESK2 Links Ensembl NCBI GeneCards UniProt Show fit	testis-specific kinase 2
chr2_+_113885138 Show fit	0.94	ENST00000409930.3	IL1RN Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor antagonist
chr19_+_55014085 Show fit	0.94	ENST00000351841.2	LAIR2 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte-associated immunoglobulin-like receptor 2
chr1_+_161087873 Show fit	0.93	ENST00000368009.2 ENST00000368007.4 ENST00000368008.1 ENST00000392190.5	NIT1 Links Ensembl NCBI GeneCards UniProt Show fit	nitrilase 1
chr7_-_87936195 Show fit	0.93	ENST00000414498.1 ENST00000301959.5 ENST00000380079.4	STEAP4 Links Ensembl NCBI GeneCards UniProt Show fit	STEAP family member 4
chr1_+_149804218 Show fit	0.86	ENST00000610125.1	HIST2H4A Links Ensembl NCBI GeneCards UniProt Show fit	histone cluster 2, H4a
chr2_+_135676381 Show fit	0.84	ENST00000537343.1 ENST00000295238.6 ENST00000264157.5	CCNT2 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin T2
chr20_-_33732952 Show fit	0.84	ENST00000541621.1	EDEM2 Links Ensembl NCBI GeneCards UniProt Show fit	ER degradation enhancer, mannosidase alpha-like 2
chr1_+_196743912 Show fit	0.84	ENST00000367425.4	CFHR3 Links Ensembl NCBI GeneCards UniProt Show fit	complement factor H-related 3
chr1_-_67519782 Show fit	0.83	ENST00000235345.5	SLC35D1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr9_-_88356789 Show fit	0.82	ENST00000357081.3 ENST00000376081.4 ENST00000337006.4 ENST00000376109.3	AGTPBP1 Links Ensembl NCBI GeneCards UniProt Show fit	ATP/GTP binding protein 1
chr19_+_55014013 Show fit	0.81	ENST00000301202.2	LAIR2 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte-associated immunoglobulin-like receptor 2
chr14_+_64971292 Show fit	0.78	ENST00000358738.3 ENST00000394712.2	ZBTB1 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 1
chr4_-_2935674 Show fit	0.75	ENST00000514800.1	MFSD10 Links Ensembl NCBI GeneCards UniProt Show fit	major facilitator superfamily domain containing 10
chr19_-_41945804 Show fit	0.75	ENST00000221943.9 ENST00000597457.1 ENST00000589970.1 ENST00000595425.1 ENST00000438807.3 ENST00000589102.1 ENST00000592922.2	ATP5SL Links Ensembl NCBI GeneCards UniProt Show fit	ATP5S-like
chr7_+_150065278 Show fit	0.74	ENST00000519397.1 ENST00000479668.1 ENST00000540729.1	REPIN1 Links Ensembl NCBI GeneCards UniProt Show fit	replication initiator 1
chr2_-_191878162 Show fit	0.73	ENST00000540176.1	STAT1 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 1, 91kDa
chr16_-_30457048 Show fit	0.73	ENST00000500504.2 ENST00000542752.1	SEPHS2 Links Ensembl NCBI GeneCards UniProt Show fit	selenophosphate synthetase 2
chrX_-_105282712 Show fit	0.70	ENST00000372563.1	SERPINA7 Links Ensembl NCBI GeneCards UniProt Show fit	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr2_-_167232484 Show fit	0.70	ENST00000375387.4 ENST00000303354.6 ENST00000409672.1	SCN9A Links Ensembl NCBI GeneCards UniProt Show fit	sodium channel, voltage-gated, type IX, alpha subunit
chr17_+_27369918 Show fit	0.70	ENST00000323372.4	PIPOX Links Ensembl NCBI GeneCards UniProt Show fit	pipecolic acid oxidase
chr5_-_58882219 Show fit	0.66	ENST00000505453.1 ENST00000360047.5	PDE4D Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D, cAMP-specific
chr2_-_191878681 Show fit	0.63	ENST00000409465.1	STAT1 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 1, 91kDa
chr9_-_77502636 Show fit	0.59	ENST00000449912.2	TRPM6 Links Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel, subfamily M, member 6
chr12_+_110011571 Show fit	0.52	ENST00000539696.1 ENST00000228510.3 ENST00000392727.3	MVK Links Ensembl NCBI GeneCards UniProt Show fit	mevalonate kinase
chr14_+_102276192 Show fit	0.50	ENST00000557714.1	PPP2R5C Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2, regulatory subunit B', gamma
chr2_-_201936302 Show fit	0.49	ENST00000453765.1 ENST00000452799.1 ENST00000446678.1 ENST00000418596.3	FAM126B Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 126, member B
chr14_-_70263979 Show fit	0.44	ENST00000216540.4	SLC10A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr4_-_119274121 Show fit	0.36	ENST00000296498.3	PRSS12 Links Ensembl NCBI GeneCards UniProt Show fit	protease, serine, 12 (neurotrypsin, motopsin)
chr12_-_110939870 Show fit	0.36	ENST00000447578.2 ENST00000546588.1 ENST00000360579.7 ENST00000549970.1 ENST00000549578.1	VPS29 Links Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 29 homolog (S. cerevisiae)
chr14_-_80697396 Show fit	0.35	ENST00000557010.1	DIO2 Links Ensembl NCBI GeneCards UniProt Show fit	deiodinase, iodothyronine, type II
chr2_-_77749474 Show fit	0.34	ENST00000409093.1 ENST00000409088.3	LRRTM4 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat transmembrane neuronal 4
chr6_+_31515337 Show fit	0.28	ENST00000376148.4 ENST00000376145.4	NFKBIL1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr3_-_122233723 Show fit	0.27	ENST00000493510.1 ENST00000344337.6 ENST00000476916.1 ENST00000465882.1	KPNA1 Links Ensembl NCBI GeneCards UniProt Show fit	karyopherin alpha 1 (importin alpha 5)
chr17_+_72427477 Show fit	0.23	ENST00000342648.5 ENST00000481232.1	GPRC5C Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor, family C, group 5, member C

View svg image
View png image

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.3	24.8	GO:0002894	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
7.2	21.5	GO:0019557	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
5.8	17.4	GO:0055073	cadmium ion homeostasis(GO:0055073)
5.4	32.6	GO:0000821	regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
5.1	25.5	GO:0015855	pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
4.8	14.3	GO:0033214	iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
4.6	9.2	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
4.2	12.7	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
4.1	12.3	GO:0002384	hepatic immune response(GO:0002384)
3.4	10.1	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
3.3	39.7	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
3.1	9.3	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
2.9	11.6	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
2.8	34.1	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
2.8	16.7	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.7	8.2	GO:0072277	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.7	16.4	GO:0034201	response to oleic acid(GO:0034201)
2.7	8.1	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
2.7	8.0	GO:2000439	negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
2.6	10.4	GO:0071727	toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
2.4	9.4	GO:0090362	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of platelet-derived growth factor production(GO:0090362) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
2.3	11.7	GO:0044793	negative regulation by host of viral process(GO:0044793) negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
2.2	9.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
2.2	8.7	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.0	21.9	GO:0090232	peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
2.0	29.5	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.9	27.2	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
1.9	25.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
1.9	3.7	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
1.7	8.3	GO:0002399	MHC class II protein complex assembly(GO:0002399)
1.6	6.2	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.5	34.9	GO:0006957	complement activation, alternative pathway(GO:0006957)
1.5	4.5	GO:1901859	late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) single-organism membrane invagination(GO:1902534)
1.4	5.6	GO:0043387	mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
1.4	9.6	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
1.3	14.3	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
1.3	5.2	GO:1904640	response to methionine(GO:1904640)
1.2	12.0	GO:0015939	pantothenate metabolic process(GO:0015939)
0.8	3.2	GO:0097368	histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.8	16.6	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.8	1.5	GO:0006097	glyoxylate cycle(GO:0006097)
0.7	2.9	GO:0072308	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.7	7.3	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.7	2.7	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.6	6.3	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.6	5.5	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.6	1.7	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.6	13.7	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.5	1.6	GO:0001978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.5	2.2	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.5	2.2	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.5	3.3	GO:0097527	Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527)
0.5	3.6	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.5	3.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.5	24.4	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.5	17.3	GO:0050832	defense response to fungus(GO:0050832)
0.5	1.5	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.5	3.0	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.5	1.4	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.5	3.7	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.4	2.7	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4	4.5	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.4	20.8	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.4	7.6	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.4	7.8	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.4	0.8	GO:0002572	pro-T cell differentiation(GO:0002572)
0.3	1.0	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.3	8.7	GO:0019731	antibacterial humoral response(GO:0019731)
0.3	0.8	GO:0036509	trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.3	1.4	GO:0048165	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3	0.8	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.3	4.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.3	1.6	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2	1.5	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.2	0.7	GO:0016260	selenocysteine biosynthetic process(GO:0016260)
0.2	0.7	GO:0046440	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2	3.7	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.2	12.9	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.2	0.8	GO:0019086	late viral transcription(GO:0019086)
0.2	3.8	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.2	2.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	2.1	GO:0072507	divalent inorganic cation homeostasis(GO:0072507)
0.2	0.9	GO:0097461	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2	0.5	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2	0.9	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2	3.2	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.1	1.2	GO:0007162	negative regulation of cell adhesion(GO:0007162)
0.1	1.8	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.1	6.0	GO:0006953	acute-phase response(GO:0006953)
0.1	0.8	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1	10.5	GO:0008285	negative regulation of cell proliferation(GO:0008285)
0.1	2.7	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	1.4	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	2.9	GO:0006379	mRNA cleavage(GO:0006379)
0.1	0.2	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
0.1	0.7	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	0.2	GO:0003218	cardiac left ventricle formation(GO:0003218) cell migration involved in vasculogenesis(GO:0035441)
0.1	2.0	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	1.3	GO:0006825	copper ion transport(GO:0006825)
0.1	2.2	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.1	0.7	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.7	GO:0048266	behavioral response to pain(GO:0048266)
0.0	1.4	GO:0030199	collagen fibril organization(GO:0030199)
0.0	1.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.3	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.3	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	1.6	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.8	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	5.7	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.0	3.3	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	6.7	GO:0010506	regulation of autophagy(GO:0010506)
0.0	0.1	GO:2000674	regulation of type B pancreatic cell apoptotic process(GO:2000674)
0.0	0.3	GO:0019054	modulation by virus of host process(GO:0019054)
0.0	1.6	GO:2000257	regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0	0.3	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	1.2	GO:0000075	cell cycle checkpoint(GO:0000075)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	12.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
2.6	36.7	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
2.3	9.2	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
2.1	10.4	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
2.0	14.3	GO:0097013	phagocytic vesicle lumen(GO:0097013)
1.3	17.4	GO:0005577	fibrinogen complex(GO:0005577)
1.2	6.2	GO:0097179	protease inhibitor complex(GO:0097179)
1.0	16.7	GO:0034366	spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.5	14.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.5	106.1	GO:0072562	blood microparticle(GO:0072562)
0.5	9.3	GO:0097225	sperm midpiece(GO:0097225)
0.4	8.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.3	28.9	GO:0043195	terminal bouton(GO:0043195)
0.3	21.9	GO:0055038	recycling endosome membrane(GO:0055038)
0.2	17.4	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.2	15.2	GO:0035580	specific granule lumen(GO:0035580)
0.2	15.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.2	3.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.2	3.6	GO:0071437	invadopodium(GO:0071437)
0.2	4.5	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.2	1.4	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	2.9	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.1	2.0	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.1	46.5	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	8.2	GO:0005902	microvillus(GO:0005902)
0.1	14.3	GO:0005882	intermediate filament(GO:0005882)
0.1	1.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.4	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.1	9.4	GO:0005901	caveola(GO:0005901)
0.1	4.0	GO:0031526	brush border membrane(GO:0031526)
0.1	11.6	GO:0016605	PML body(GO:0016605)
0.1	0.8	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1	1.1	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	6.2	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1	8.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	8.1	GO:0005884	actin filament(GO:0005884)
0.1	9.2	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1	0.7	GO:0001518	voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1	0.7	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	3.3	GO:0005844	polysome(GO:0005844)
0.1	2.7	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.8	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	6.3	GO:0043204	perikaryon(GO:0043204)
0.0	5.9	GO:0031225	anchored component of membrane(GO:0031225)
0.0	51.0	GO:0005615	extracellular space(GO:0005615)
0.0	2.1	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	2.2	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	2.6	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	16.7	GO:0030054	cell junction(GO:0030054)
0.0	6.9	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	0.8	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	1.8	GO:0072686	mitotic spindle(GO:0072686)
0.0	3.8	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.7	GO:0044438	microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0	3.3	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.5	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	2.1	GO:0030667	secretory granule membrane(GO:0030667)
0.0	1.3	GO:0032587	ruffle membrane(GO:0032587)
0.0	1.2	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	19.9	GO:0005783	endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.4	29.5	GO:0004074	biliverdin reductase activity(GO:0004074)
6.4	25.5	GO:0015254	glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
5.8	17.4	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
5.4	21.5	GO:0016841	ammonia-lyase activity(GO:0016841)
4.5	27.2	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
4.1	20.5	GO:0017159	pantetheine hydrolase activity(GO:0017159)
3.5	10.4	GO:0016019	peptidoglycan receptor activity(GO:0016019)
3.2	12.7	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
3.1	9.3	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
3.0	32.6	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
2.7	8.2	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
2.7	8.0	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
2.6	7.8	GO:0004915	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
2.4	14.3	GO:1990254	keratin filament binding(GO:1990254)
2.4	9.4	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
1.9	9.6	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
1.7	5.2	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.6	4.9	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
1.6	12.9	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
1.5	9.2	GO:0030492	hemoglobin binding(GO:0030492)
1.5	11.7	GO:0001849	complement component C1q binding(GO:0001849)
1.4	5.7	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
1.2	3.7	GO:0070052	collagen V binding(GO:0070052)
1.2	3.7	GO:0032427	GBD domain binding(GO:0032427)
1.1	5.5	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
1.0	3.0	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.9	16.4	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.8	16.7	GO:0051787	misfolded protein binding(GO:0051787)
0.8	37.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.8	4.5	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.7	4.5	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.7	4.5	GO:0042610	CD8 receptor binding(GO:0042610)
0.7	21.9	GO:0043015	gamma-tubulin binding(GO:0043015)
0.7	21.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.7	18.1	GO:0001848	complement binding(GO:0001848)
0.7	51.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.7	3.3	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.6	7.8	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5	49.9	GO:0005518	collagen binding(GO:0005518)
0.5	9.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.5	1.5	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.5	1.4	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.5	2.7	GO:0004522	ribonuclease A activity(GO:0004522)
0.5	2.3	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.4	2.7	GO:0004630	phospholipase D activity(GO:0004630)
0.4	1.6	GO:0031716	calcitonin receptor binding(GO:0031716)
0.4	1.5	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3	14.3	GO:0042056	chemoattractant activity(GO:0042056)
0.3	2.6	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3	10.4	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.3	74.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.3	5.3	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.3	8.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.2	0.7	GO:0016781	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.2	0.9	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2	23.1	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2	8.3	GO:0042605	peptide antigen binding(GO:0042605)
0.2	1.0	GO:0089720	caspase binding(GO:0089720)
0.2	2.6	GO:0050700	CARD domain binding(GO:0050700)
0.2	1.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	2.4	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	1.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	2.2	GO:0070513	death domain binding(GO:0070513)
0.1	0.8	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	7.6	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.1	1.6	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	5.6	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	0.7	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.8	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	9.0	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	9.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.8	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	1.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	1.6	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	3.2	GO:0004407	histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.1	2.1	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	0.3	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	3.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.4	GO:0019534	toxin transporter activity(GO:0019534)
0.0	1.2	GO:0003951	NAD+ kinase activity(GO:0003951)
0.0	1.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.8	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	19.8	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	1.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	1.1	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.7	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	1.7	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	3.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	1.7	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	6.7	GO:0003779	actin binding(GO:0003779)
0.0	2.4	GO:0003735	structural constituent of ribosome(GO:0003735)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	24.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.7	29.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.7	36.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.6	12.3	ST STAT3 PATHWAY	STAT3 Pathway
0.6	18.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.6	30.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.4	23.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.4	9.4	PID S1P S1P1 PATHWAY	S1P1 pathway
0.4	2.9	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.4	52.9	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.3	8.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.3	15.1	PID BMP PATHWAY	BMP receptor signaling
0.2	3.6	PID S1P S1P2 PATHWAY	S1P2 pathway
0.2	7.8	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.2	3.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	8.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	15.7	PID IL12 2PATHWAY	IL12-mediated signaling events
0.2	3.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	14.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	2.3	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	3.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	41.3	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	3.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	6.6	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	2.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	1.2	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	1.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.8	PID PLK1 PATHWAY	PLK1 signaling events
0.0	5.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.3	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.4	92.9	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
1.8	25.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
1.7	17.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
1.4	36.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.1	29.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.9	10.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.9	16.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.8	15.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.8	16.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.8	18.7	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.6	24.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.6	3.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.6	24.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.6	13.7	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.5	30.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.5	24.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.4	14.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4	6.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.4	4.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.4	5.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.4	8.3	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.4	8.3	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3	14.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2	27.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.2	3.6	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.2	26.5	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2	3.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.2	2.9	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	3.7	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.1	24.0	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.1	3.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	8.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	10.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	1.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	2.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	8.3	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.1	4.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	1.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.3	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	3.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.5	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	3.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.8	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.8	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions