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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CPEB1

Z-value: 1.42

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Transcription factors associated with CPEB1

Gene Symbol Gene ID Gene Info
CPEB1
ENSG00000214575.5 cytoplasmic polyadenylation element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CPEB1hg19_v2_chr15_-_83240507_83240539-0.335.6e-07Click!

Activity profile of CPEB1 motif

Sorted Z-values of CPEB1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_56078695 35.35 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr12_-_54071181 27.34 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr2_-_151344172 25.35 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr11_-_11374904 23.37 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr1_-_32384693 20.74 ENST00000602683.1
ENST00000470404.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr10_+_114709999 17.17 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr6_+_111195973 16.63 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr17_-_38574169 15.86 ENST00000423485.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr22_+_41258250 15.59 ENST00000544094.1
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr3_-_141747439 15.58 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr16_-_2314222 15.55 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr4_+_174089904 14.66 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr12_-_52967600 14.33 ENST00000549343.1
ENST00000305620.2
KRT74
keratin 74
chr14_+_56127989 14.23 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr19_+_36036477 13.79 ENST00000222284.5
ENST00000392204.2
TMEM147
transmembrane protein 147
chr2_-_190044480 13.09 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr19_+_36036583 12.51 ENST00000392205.1
TMEM147
transmembrane protein 147
chr3_+_142342228 12.36 ENST00000337777.3
PLS1
plastin 1
chr4_-_102268628 12.23 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr11_-_27723158 12.15 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr14_-_102552659 11.89 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr11_+_57529234 11.87 ENST00000360682.6
ENST00000361796.4
ENST00000529526.1
ENST00000426142.2
ENST00000399050.4
ENST00000361391.6
ENST00000361332.4
ENST00000532463.1
ENST00000529986.1
ENST00000358694.6
ENST00000532787.1
ENST00000533667.1
ENST00000532649.1
ENST00000528621.1
ENST00000530748.1
ENST00000428599.2
ENST00000527467.1
ENST00000528232.1
ENST00000531014.1
ENST00000526772.1
ENST00000529873.1
ENST00000525902.1
ENST00000532844.1
ENST00000526357.1
ENST00000530094.1
ENST00000415361.2
ENST00000532245.1
ENST00000534579.1
ENST00000526938.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr10_-_13390021 11.82 ENST00000537130.1
SEPHS1
selenophosphate synthetase 1
chr20_+_30193083 11.69 ENST00000376112.3
ENST00000376105.3
ID1
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr3_+_159570722 11.62 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr2_+_181845843 11.48 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr17_-_4852332 11.40 ENST00000572383.1
PFN1
profilin 1
chrX_+_106871713 11.39 ENST00000372435.4
ENST00000372428.4
ENST00000372419.3
ENST00000543248.1
PRPS1
phosphoribosyl pyrophosphate synthetase 1
chr18_-_33702078 11.29 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr4_-_102267953 11.29 ENST00000523694.2
ENST00000507176.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chrX_-_20236970 10.79 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_-_89357179 10.78 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
GTF2B
general transcription factor IIB
chr4_-_102268484 10.64 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_+_42671887 10.52 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr10_-_126847276 10.41 ENST00000531469.1
CTBP2
C-terminal binding protein 2
chr3_+_158991025 10.31 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr15_+_80364901 10.27 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chr2_-_148779106 9.86 ENST00000416719.1
ENST00000264169.2
ORC4
origin recognition complex, subunit 4
chr8_+_71485681 9.84 ENST00000391684.1
AC120194.1
AC120194.1
chr12_+_28410128 9.83 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr18_+_3252265 9.74 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr17_-_39684550 9.68 ENST00000455635.1
ENST00000361566.3
KRT19
keratin 19
chr15_-_60690163 9.55 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr14_+_73563735 9.52 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr9_-_69229650 9.47 ENST00000416428.1
CBWD6
COBW domain containing 6
chr6_+_44194762 9.40 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr7_+_100464760 9.40 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr6_+_119215308 9.36 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr17_-_36358166 8.97 ENST00000537432.1
TBC1D3
TBC1 domain family, member 3
chr1_+_84630645 8.95 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_-_140070897 8.85 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
HARS
histidyl-tRNA synthetase
chr11_+_35160709 8.84 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
CD44
CD44 molecule (Indian blood group)
chr8_+_104831554 8.80 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr9_-_86593238 8.79 ENST00000351839.3
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr5_-_78808617 8.57 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr1_+_169077172 8.52 ENST00000499679.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_-_111091948 8.50 ENST00000447165.2
NREP
neuronal regeneration related protein
chr10_+_114710211 8.40 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr3_-_69129501 8.26 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3
ubiquitin-like modifier activating enzyme 3
chr17_-_4852243 8.16 ENST00000225655.5
PFN1
profilin 1
chrX_-_100662881 8.05 ENST00000218516.3
GLA
galactosidase, alpha
chr19_+_36142147 8.03 ENST00000590618.1
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr10_+_47894023 7.92 ENST00000358474.5
FAM21B
family with sequence similarity 21, member B
chr9_+_131452239 7.83 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr6_+_12290586 7.81 ENST00000379375.5
EDN1
endothelin 1
chr9_-_70465758 7.80 ENST00000489273.1
CBWD5
COBW domain containing 5
chr14_-_35344093 7.74 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr13_-_31040060 7.71 ENST00000326004.4
ENST00000341423.5
HMGB1
high mobility group box 1
chr18_-_33709268 7.68 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr8_+_9953061 7.59 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr7_-_27205136 7.41 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr1_+_26798955 7.40 ENST00000361427.5
HMGN2
high mobility group nucleosomal binding domain 2
chr12_-_50616382 7.29 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr1_+_95616933 7.23 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr2_-_175711133 7.21 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr7_+_115862858 7.19 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr6_+_26104104 7.06 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chr16_+_2820912 6.99 ENST00000570539.1
SRRM2
serine/arginine repetitive matrix 2
chr3_+_158787041 6.95 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr4_-_111119804 6.93 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr2_-_207023918 6.87 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_+_44870866 6.86 ENST00000355387.2
ENST00000361799.2
RNF220
ring finger protein 220
chr19_+_36119929 6.81 ENST00000588161.1
ENST00000262633.4
ENST00000592202.1
ENST00000586618.1
RBM42
RNA binding motif protein 42
chr6_+_114178512 6.72 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_+_244214577 6.69 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr15_-_56209306 6.69 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr16_+_1728257 6.63 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
HN1L
hematological and neurological expressed 1-like
chr6_+_21593972 6.59 ENST00000244745.1
ENST00000543472.1
SOX4
SRY (sex determining region Y)-box 4
chr17_-_17480779 6.47 ENST00000395782.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr8_+_9953214 6.32 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr5_+_162932554 6.28 ENST00000321757.6
ENST00000421814.2
ENST00000518095.1
MAT2B
methionine adenosyltransferase II, beta
chr3_+_107241783 6.15 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr7_-_27219849 6.12 ENST00000396344.4
HOXA10
homeobox A10
chr15_-_37390482 5.96 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr4_-_48782259 5.89 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr20_-_30310336 5.88 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr5_+_135496675 5.72 ENST00000507637.1
SMAD5
SMAD family member 5
chr1_-_156675535 5.67 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr12_-_49412541 5.61 ENST00000547306.1
ENST00000548857.1
ENST00000551696.1
ENST00000316299.5
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr10_-_118764862 5.60 ENST00000260777.10
KIAA1598
KIAA1598
chr10_-_118765081 5.56 ENST00000392903.2
ENST00000355371.4
KIAA1598
KIAA1598
chr6_-_27114577 5.56 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr17_+_45286706 5.55 ENST00000393450.1
ENST00000572303.1
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr6_+_27114861 5.51 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr6_+_15246501 5.46 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr17_+_45286387 5.42 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr12_-_49412588 5.36 ENST00000547082.1
ENST00000395170.3
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr2_-_85645545 5.29 ENST00000409275.1
CAPG
capping protein (actin filament), gelsolin-like
chr19_+_36120009 5.26 ENST00000589871.1
RBM42
RNA binding motif protein 42
chr1_+_84630053 5.22 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_-_37216055 5.19 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr1_+_164528866 5.18 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr13_+_28519343 5.13 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr1_-_115259337 5.08 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr10_-_13390270 5.00 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
SEPHS1
selenophosphate synthetase 1
chr17_+_7462103 4.98 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr3_-_33700589 4.97 ENST00000461133.3
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr10_-_104262460 4.95 ENST00000446605.2
ENST00000369905.4
ENST00000545684.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr1_-_32110467 4.82 ENST00000440872.2
ENST00000373703.4
PEF1
penta-EF-hand domain containing 1
chr7_+_116654935 4.81 ENST00000432298.1
ENST00000422922.1
ST7
suppression of tumorigenicity 7
chr8_+_77593474 4.80 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr6_+_30585486 4.74 ENST00000259873.4
ENST00000506373.2
MRPS18B
mitochondrial ribosomal protein S18B
chr2_+_8822113 4.66 ENST00000396290.1
ENST00000331129.3
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr6_+_108977520 4.64 ENST00000540898.1
FOXO3
forkhead box O3
chr5_-_73937244 4.64 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr10_+_47894572 4.60 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr1_+_145883868 4.57 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr4_+_74735102 4.56 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr1_-_9129895 4.52 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr2_+_163175394 4.47 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr6_-_31697977 4.47 ENST00000375787.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr5_-_98262240 4.44 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr17_-_27418537 4.42 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr2_-_2334888 4.42 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr20_+_31407692 4.41 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chrX_+_123095546 4.40 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr4_+_160188889 4.30 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_-_55277654 4.26 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4
reticulon 4
chr10_+_111967345 4.24 ENST00000332674.5
ENST00000453116.1
MXI1
MAX interactor 1, dimerization protein
chr17_+_7462031 4.23 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_62473706 4.21 ENST00000403550.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr10_+_102106829 4.20 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr18_+_3252206 4.15 ENST00000578562.2
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr11_-_62432641 4.15 ENST00000528405.1
ENST00000524958.1
ENST00000525675.1
RP11-831H9.11
C11orf48
Uncharacterized protein
chromosome 11 open reading frame 48
chr4_-_40631859 4.12 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chr17_+_39846114 4.10 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr3_-_196911002 4.04 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr19_+_36706024 4.01 ENST00000443387.2
ZNF146
zinc finger protein 146
chr12_-_49412525 3.99 ENST00000551121.1
ENST00000552212.1
ENST00000548605.1
ENST00000548950.1
ENST00000547125.1
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr10_-_74856608 3.99 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr1_-_149814478 3.91 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr8_+_77593448 3.88 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr13_-_46543805 3.85 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr4_-_105416039 3.79 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr19_+_36119975 3.78 ENST00000589559.1
ENST00000360475.4
RBM42
RNA binding motif protein 42
chr15_-_55562479 3.73 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr14_+_103058948 3.72 ENST00000262241.6
RCOR1
REST corepressor 1
chr15_-_55541227 3.71 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr10_-_104262426 3.67 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr17_+_7461613 3.65 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr3_-_33700933 3.63 ENST00000480013.1
CLASP2
cytoplasmic linker associated protein 2
chr3_-_196910721 3.53 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr1_+_23345930 3.51 ENST00000356634.3
KDM1A
lysine (K)-specific demethylase 1A
chr6_-_41909191 3.50 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr12_-_118797475 3.50 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chrX_-_77395186 3.44 ENST00000341864.5
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr5_+_92919043 3.38 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr11_+_34642656 3.37 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr11_-_62473776 3.35 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_+_167298281 3.34 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr5_+_112074029 3.34 ENST00000512211.2
APC
adenomatous polyposis coli
chr18_+_19749386 3.32 ENST00000269216.3
GATA6
GATA binding protein 6
chr1_-_156675368 3.22 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr1_+_161736072 3.16 ENST00000367942.3
ATF6
activating transcription factor 6
chr1_+_23345943 3.14 ENST00000400181.4
ENST00000542151.1
KDM1A
lysine (K)-specific demethylase 1A
chr1_-_167059830 3.13 ENST00000367868.3
GPA33
glycoprotein A33 (transmembrane)
chr2_-_145277569 3.12 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr1_+_82266053 3.06 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr13_+_22245522 3.03 ENST00000382353.5
FGF9
fibroblast growth factor 9
chr6_+_31683117 2.89 ENST00000375825.3
ENST00000375824.1
LY6G6D
lymphocyte antigen 6 complex, locus G6D
chr4_-_74864386 2.88 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr17_+_7461580 2.74 ENST00000483039.1
ENST00000396542.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr12_-_81763127 2.70 ENST00000541017.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr3_-_141747459 2.70 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr3_+_69928256 2.69 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr17_+_39411636 2.64 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chr5_-_142782862 2.58 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr18_-_25616519 2.57 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chrX_-_122756660 2.54 ENST00000441692.1
THOC2
THO complex 2
chr18_-_3219847 2.45 ENST00000261606.7
MYOM1
myomesin 1
chr8_+_104831472 2.44 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr19_-_57967854 2.42 ENST00000321039.3
VN1R1
vomeronasal 1 receptor 1
chr9_+_2159850 2.41 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrX_-_114252193 2.40 ENST00000243213.1
IL13RA2
interleukin 13 receptor, alpha 2
chr17_-_34417479 2.38 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr5_-_88119580 2.35 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr8_-_95274536 2.32 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr3_-_197300194 2.32 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr3_+_51575596 2.22 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr5_-_82969405 2.16 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CPEB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.4 34.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
5.6 16.8 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
5.5 16.6 GO:0006597 spermine biosynthetic process(GO:0006597)
4.1 16.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
4.0 12.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
3.9 11.7 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
3.4 10.3 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
3.3 6.6 GO:0046098 guanine metabolic process(GO:0046098)
3.3 13.1 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
3.0 11.9 GO:0043335 protein unfolding(GO:0043335)
2.9 8.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
2.8 11.4 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
2.8 14.2 GO:0097338 response to clozapine(GO:0097338)
2.8 8.3 GO:0007113 endomitotic cell cycle(GO:0007113)
2.7 10.8 GO:1904798 positive regulation of core promoter binding(GO:1904798)
2.6 7.8 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
2.5 12.4 GO:1902896 terminal web assembly(GO:1902896)
2.4 14.1 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
2.2 8.8 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.2 6.6 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
2.1 8.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
2.0 18.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
2.0 19.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
1.9 7.7 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
1.9 19.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.9 9.4 GO:0015862 uridine transport(GO:0015862)
1.9 9.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.6 15.9 GO:0030263 resolution of meiotic recombination intermediates(GO:0000712) apoptotic chromosome condensation(GO:0030263)
1.6 6.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.5 4.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
1.5 13.9 GO:0030091 protein repair(GO:0030091)
1.5 4.4 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.4 4.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
1.4 8.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.3 11.7 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
1.3 7.6 GO:1903286 regulation of potassium ion import(GO:1903286)
1.2 4.8 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
1.2 4.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
1.2 4.7 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
1.2 10.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.2 6.9 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.1 8.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.1 3.3 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
1.1 8.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.1 6.5 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
1.1 8.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.0 31.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
1.0 8.1 GO:0016139 glycoside catabolic process(GO:0016139)
1.0 5.7 GO:0001880 Mullerian duct regression(GO:0001880)
0.9 9.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.9 2.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.9 2.6 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.9 27.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.8 5.9 GO:0060154 response to cycloheximide(GO:0046898) cellular process regulating host cell cycle in response to virus(GO:0060154)
0.8 4.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.8 9.8 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.8 2.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.7 4.8 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.7 2.7 GO:0060025 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) regulation of synaptic activity(GO:0060025)
0.6 3.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.6 7.4 GO:0042118 endothelial cell activation(GO:0042118)
0.6 4.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.6 4.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.6 3.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.6 1.7 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.5 1.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.5 4.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.5 5.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.5 4.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.5 4.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.5 3.5 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.5 26.3 GO:0031648 protein destabilization(GO:0031648)
0.5 1.9 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.5 0.5 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.5 1.9 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.5 4.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.5 2.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.5 5.9 GO:0090527 actin filament reorganization(GO:0090527)
0.4 4.5 GO:0006527 arginine catabolic process(GO:0006527)
0.4 1.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.4 11.9 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.4 5.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 18.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4 2.1 GO:0035989 tendon development(GO:0035989)
0.4 10.3 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.4 8.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 4.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.4 1.9 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.4 3.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.4 7.8 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.4 11.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.4 6.7 GO:0051764 actin crosslink formation(GO:0051764)
0.3 11.3 GO:0003094 glomerular filtration(GO:0003094)
0.3 3.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.3 11.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.3 5.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 7.6 GO:0034389 lipid particle organization(GO:0034389)
0.3 2.6 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.3 1.6 GO:0035063 nuclear speck organization(GO:0035063)
0.3 2.4 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.3 2.4 GO:0043308 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.3 2.0 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3 3.4 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.3 2.0 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 10.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.3 14.7 GO:0016266 O-glycan processing(GO:0016266)
0.3 11.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.3 2.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.3 11.1 GO:0006270 DNA replication initiation(GO:0006270)
0.3 2.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 0.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 8.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 1.6 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.2 1.1 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.2 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.2 0.7 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.2 4.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.2 1.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 3.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 7.3 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.2 0.6 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 5.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.2 5.5 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.2 4.4 GO:0048665 neuron fate specification(GO:0048665)
0.2 4.2 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.2 0.7 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.5 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.2 0.5 GO:0006711 estrogen catabolic process(GO:0006711)
0.2 3.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 2.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 0.2 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 1.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.2 5.1 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.2 18.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 15.0 GO:0006110 regulation of glycolytic process(GO:0006110)
0.1 0.9 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.8 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 0.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 2.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.2 GO:0032364 oxygen homeostasis(GO:0032364) hemoglobin biosynthetic process(GO:0042541)
0.1 4.3 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 31.6 GO:0007018 microtubule-based movement(GO:0007018)
0.1 8.1 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 2.9 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 8.6 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 4.1 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 6.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 4.4 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1 6.0 GO:0031016 pancreas development(GO:0031016)
0.1 0.5 GO:2000503 regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 4.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 10.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.7 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 1.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 4.0 GO:0014047 glutamate secretion(GO:0014047)
0.1 0.6 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 1.2 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 1.1 GO:0061436 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.1 2.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 12.7 GO:0030307 positive regulation of cell growth(GO:0030307)
0.1 5.5 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.5 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 0.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.1 1.2 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.1 1.3 GO:0010458 exit from mitosis(GO:0010458)
0.1 0.3 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 4.7 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 0.8 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 1.5 GO:0030516 regulation of axon extension(GO:0030516)
0.0 1.4 GO:0006260 DNA replication(GO:0006260)
0.0 0.2 GO:1990481 tRNA pseudouridine synthesis(GO:0031119) mRNA pseudouridine synthesis(GO:1990481)
0.0 1.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0071600 otic vesicle formation(GO:0030916) otic vesicle morphogenesis(GO:0071600)
0.0 0.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 5.7 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 3.4 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 3.3 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 2.0 GO:0051180 vitamin transport(GO:0051180)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 14.0 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.7 GO:0007565 female pregnancy(GO:0007565)
0.0 2.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.4 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.4 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.2 GO:1903209 positive regulation of oxidative stress-induced cell death(GO:1903209)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.6 GO:0060348 bone development(GO:0060348)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.9 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
4.4 13.1 GO:0005588 collagen type V trimer(GO:0005588)
3.8 34.2 GO:0005955 calcineurin complex(GO:0005955)
3.7 22.0 GO:1990357 terminal web(GO:1990357)
2.8 11.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
2.4 14.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
2.1 6.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
2.0 7.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.9 9.6 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
1.9 9.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
1.7 15.5 GO:0061574 ASAP complex(GO:0061574)
1.5 27.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.4 8.6 GO:0002177 manchette(GO:0002177)
1.4 6.9 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
1.3 4.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
1.3 8.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.1 4.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.0 14.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.0 10.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.0 6.8 GO:0016342 catenin complex(GO:0016342)
0.9 3.7 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.9 10.7 GO:0005915 zonula adherens(GO:0005915)
0.9 8.6 GO:0045180 basal cortex(GO:0045180)
0.9 11.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.8 10.4 GO:0097470 ribbon synapse(GO:0097470)
0.8 2.3 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.8 8.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.7 15.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.7 5.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.7 7.7 GO:0031010 ISWI-type complex(GO:0031010)
0.6 7.6 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.6 19.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.5 2.7 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.5 5.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 8.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 6.7 GO:0043073 germ cell nucleus(GO:0043073)
0.4 2.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.4 2.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 5.3 GO:0008290 F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.3 2.3 GO:0098576 lumenal side of membrane(GO:0098576)
0.3 15.7 GO:0048786 presynaptic active zone(GO:0048786)
0.3 1.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 23.5 GO:0016459 myosin complex(GO:0016459)
0.2 5.7 GO:0071141 SMAD protein complex(GO:0071141)
0.2 2.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 3.4 GO:0000124 SAGA complex(GO:0000124)
0.2 5.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 4.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 4.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 10.4 GO:1990391 DNA repair complex(GO:1990391)
0.2 4.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 0.8 GO:0030425 dendrite(GO:0030425)
0.1 4.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 6.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.3 GO:0030478 actin cap(GO:0030478)
0.1 44.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 24.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 7.0 GO:0002102 podosome(GO:0002102)
0.1 12.3 GO:0032587 ruffle membrane(GO:0032587)
0.1 7.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 10.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 2.3 GO:0051233 spindle midzone(GO:0051233)
0.1 7.0 GO:0015030 Cajal body(GO:0015030)
0.1 2.4 GO:0071564 npBAF complex(GO:0071564)
0.1 0.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 6.5 GO:0031526 brush border membrane(GO:0031526)
0.1 3.6 GO:0043034 costamere(GO:0043034)
0.1 12.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 4.4 GO:0000786 nucleosome(GO:0000786)
0.1 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 6.2 GO:0005811 lipid particle(GO:0005811)
0.1 3.5 GO:0035579 specific granule membrane(GO:0035579)
0.1 22.3 GO:0005938 cell cortex(GO:0005938)
0.1 26.2 GO:0005769 early endosome(GO:0005769)
0.1 3.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.6 GO:0010369 chromocenter(GO:0010369)
0.1 1.2 GO:0043234 protein complex(GO:0043234)
0.1 0.8 GO:0043194 axon initial segment(GO:0043194)
0.0 8.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 21.1 GO:0005925 focal adhesion(GO:0005925)
0.0 3.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.8 GO:0005604 basement membrane(GO:0005604)
0.0 2.4 GO:0030175 filopodium(GO:0030175)
0.0 7.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.8 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 10.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.1 GO:0031975 organelle envelope(GO:0031967) envelope(GO:0031975)
0.0 23.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 5.9 GO:0005681 spliceosomal complex(GO:0005681)
0.0 2.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 15.7 GO:0005815 microtubule organizing center(GO:0005815)
0.0 6.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.7 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 4.4 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 3.0 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.8 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
5.3 15.9 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
5.2 20.7 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
4.0 12.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
3.4 10.3 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
3.4 34.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
2.8 13.9 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
2.7 11.0 GO:0032038 myosin II heavy chain binding(GO:0032038)
2.2 6.5 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
2.0 8.1 GO:0016936 galactoside binding(GO:0016936)
1.9 11.1 GO:1990254 keratin filament binding(GO:1990254)
1.8 29.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
1.7 6.6 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
1.6 19.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
1.6 9.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.6 7.8 GO:0031708 endothelin B receptor binding(GO:0031708)
1.5 10.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.4 4.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
1.3 7.7 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
1.2 32.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.2 7.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.2 11.9 GO:0030911 TPR domain binding(GO:0030911)
1.2 6.9 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.1 21.3 GO:0045295 gamma-catenin binding(GO:0045295)
1.0 8.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
1.0 19.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.0 14.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.0 6.7 GO:0050815 phosphoserine binding(GO:0050815)
0.9 4.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.9 4.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.8 4.0 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.8 2.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.8 43.6 GO:0019894 kinesin binding(GO:0019894)
0.7 7.6 GO:0097016 L27 domain binding(GO:0097016)
0.7 11.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.6 8.9 GO:0016918 retinal binding(GO:0016918)
0.6 8.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.5 13.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 2.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 8.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.5 2.6 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.5 3.5 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.5 1.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.5 2.0 GO:0008431 vitamin E binding(GO:0008431)
0.5 2.9 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.5 2.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.5 20.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.4 9.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.4 5.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.4 6.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 1.2 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.4 18.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 10.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 7.3 GO:0070628 proteasome binding(GO:0070628)
0.3 3.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 8.5 GO:0031489 myosin V binding(GO:0031489)
0.3 6.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 10.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 16.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.3 15.0 GO:0030145 manganese ion binding(GO:0030145)
0.3 2.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 8.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 11.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 7.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 2.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 9.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 5.5 GO:0032452 histone demethylase activity(GO:0032452)
0.2 1.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 8.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 7.3 GO:0003785 actin monomer binding(GO:0003785)
0.2 9.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 7.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 7.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 2.3 GO:0038132 neuregulin binding(GO:0038132)
0.2 3.2 GO:0035497 cAMP response element binding(GO:0035497)
0.2 1.9 GO:0050544 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.2 1.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 3.7 GO:0051371 muscle alpha-actinin binding(GO:0051371) structural molecule activity conferring elasticity(GO:0097493)
0.1 6.7 GO:0005080 protein kinase C binding(GO:0005080)
0.1 7.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 2.7 GO:0035198 miRNA binding(GO:0035198)
0.1 4.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 1.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 2.2 GO:0008494 translation activator activity(GO:0008494)
0.1 4.8 GO:0005109 frizzled binding(GO:0005109)
0.1 20.9 GO:0042393 histone binding(GO:0042393)
0.1 0.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 3.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.3 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 9.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 8.5 GO:0046983 protein dimerization activity(GO:0046983)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 3.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 16.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 32.8 GO:0003924 GTPase activity(GO:0003924)
0.1 4.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 1.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 2.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 5.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 32.5 GO:0045296 cadherin binding(GO:0045296)
0.1 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 1.1 GO:0070888 E-box binding(GO:0070888)
0.1 2.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.7 GO:0043422 protein kinase B binding(GO:0043422)
0.0 4.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.3 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 6.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 7.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 14.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.3 GO:0046332 SMAD binding(GO:0046332)
0.0 4.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 6.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.4 GO:0004386 helicase activity(GO:0004386)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 31.1 PID IL3 PATHWAY IL3-mediated signaling events
0.6 20.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.5 16.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.5 2.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.5 11.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.5 11.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.4 27.5 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.4 8.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.4 5.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 15.8 NABA COLLAGENS Genes encoding collagen proteins
0.3 18.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 5.7 PID ALK2 PATHWAY ALK2 signaling events
0.3 16.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.3 8.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 7.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 24.2 PID E2F PATHWAY E2F transcription factor network
0.2 14.7 PID LKB1 PATHWAY LKB1 signaling events
0.2 9.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 10.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 16.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 18.5 PID AP1 PATHWAY AP-1 transcription factor network
0.2 7.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 14.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 3.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 2.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 1.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 2.4 ST GAQ PATHWAY G alpha q Pathway
0.1 11.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 7.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 3.9 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 5.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 4.4 PID PLK1 PATHWAY PLK1 signaling events
0.1 5.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 4.8 PID P73PATHWAY p73 transcription factor network
0.1 1.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 4.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 8.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 19.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.9 11.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.7 15.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.7 11.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.7 40.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.7 16.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.6 6.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 23.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.5 8.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 5.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.4 7.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 13.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 6.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 18.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.3 15.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.3 14.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.3 8.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 16.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.3 6.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 7.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 8.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 15.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 6.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 14.9 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2 3.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 6.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 8.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 2.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 9.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 8.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 10.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 14.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 3.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 13.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 4.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 2.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 5.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 31.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 4.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 4.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 5.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 4.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 2.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 6.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors