averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
CREB1 Links Ensembl NCBI GeneCards UniProt	ENSG00000118260.10	cAMP responsive element binding protein 1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CREB1	hg19_v2_chr2_+_208394794_208394834	0.58	8.3e-21	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_-_17104356 Show fit	102.06	ENST00000361272.4 ENST00000523917.1	CNOT7 Links Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex, subunit 7
chr6_-_43027105 Show fit	54.33	ENST00000230413.5 ENST00000487429.1 ENST00000489623.1 ENST00000468957.1	MRPL2 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L2
chr3_+_45017722 Show fit	53.21	ENST00000265564.7	EXOSC7 Links Ensembl NCBI GeneCards UniProt Show fit	exosome component 7
chr12_+_108079664 Show fit	45.35	ENST00000541166.1	PWP1 Links Ensembl NCBI GeneCards UniProt Show fit	PWP1 homolog (S. cerevisiae)
chr1_-_53704157 Show fit	43.08	ENST00000371466.4 ENST00000371470.3	MAGOH Links Ensembl NCBI GeneCards UniProt Show fit	mago-nashi homolog, proliferation-associated (Drosophila)
chr15_-_34394119 Show fit	36.44	ENST00000256545.4	EMC7 Links Ensembl NCBI GeneCards UniProt Show fit	ER membrane protein complex subunit 7
chr6_-_31926208 Show fit	36.25	ENST00000454913.1 ENST00000436289.2	NELFE Links Ensembl NCBI GeneCards UniProt Show fit	negative elongation factor complex member E
chr14_+_105219437 Show fit	35.13	ENST00000329967.6 ENST00000347067.5 ENST00000553810.1	SIVA1 Links Ensembl NCBI GeneCards UniProt Show fit	SIVA1, apoptosis-inducing factor
chr12_+_132628963 Show fit	34.09	ENST00000330579.1	NOC4L Links Ensembl NCBI GeneCards UniProt Show fit	nucleolar complex associated 4 homolog (S. cerevisiae)
chr12_+_69633372 Show fit	32.36	ENST00000456847.3 ENST00000266679.8	CPSF6 Links Ensembl NCBI GeneCards UniProt Show fit	cleavage and polyadenylation specific factor 6, 68kDa
chr6_-_31926629 Show fit	31.13	ENST00000375425.5 ENST00000426722.1 ENST00000441998.1 ENST00000444811.2 ENST00000375429.3	NELFE Links Ensembl NCBI GeneCards UniProt Show fit	negative elongation factor complex member E
chrX_-_153285395 Show fit	30.17	ENST00000369980.3	IRAK1 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin-1 receptor-associated kinase 1
chr15_-_34394008 Show fit	29.93	ENST00000527822.1 ENST00000528949.1	EMC7 Links Ensembl NCBI GeneCards UniProt Show fit	ER membrane protein complex subunit 7
chr3_-_53290016 Show fit	29.24	ENST00000423525.2 ENST00000423516.1 ENST00000296289.6 ENST00000462138.1	TKT Links Ensembl NCBI GeneCards UniProt Show fit	transketolase
chr17_+_8152590 Show fit	28.29	ENST00000584044.1 ENST00000314666.6 ENST00000545834.1 ENST00000581242.1	PFAS Links Ensembl NCBI GeneCards UniProt Show fit	phosphoribosylformylglycinamidine synthase
chr1_-_145827015 Show fit	27.75	ENST00000534502.1 ENST00000313835.9 ENST00000454423.3	GPR89A Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 89A
chr9_+_70856899 Show fit	26.53	ENST00000377342.5 ENST00000478048.1	CBWD3 Links Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 3
chr6_-_31774714 Show fit	26.38	ENST00000375661.5	LSM2 Links Ensembl NCBI GeneCards UniProt Show fit	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_-_685559 Show fit	26.03	ENST00000301329.6	GLOD4 Links Ensembl NCBI GeneCards UniProt Show fit	glyoxalase domain containing 4
chr2_-_29093132 Show fit	25.94	ENST00000306108.5	TRMT61B Links Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 61 homolog B (S. cerevisiae)
chr14_+_23776167 Show fit	25.83	ENST00000554635.1 ENST00000557008.1	BCL2L2 Links Ensembl NCBI GeneCards UniProt Show fit BCL2L2-PABPN1 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2-like 2 BCL2L2-PABPN1 readthrough
chr9_-_69262509 Show fit	25.81	ENST00000377449.1 ENST00000382399.4 ENST00000377439.1 ENST00000377441.1 ENST00000377457.5	CBWD6 Links Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 6
chr9_-_179018 Show fit	25.74	ENST00000431099.2 ENST00000382447.4 ENST00000382389.1 ENST00000377447.3 ENST00000314367.10 ENST00000356521.4 ENST00000382393.1 ENST00000377400.4	CBWD1 Links Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 1
chr11_-_62607036 Show fit	25.64	ENST00000311713.7 ENST00000278856.4	WDR74 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 74
chr12_-_124118296 Show fit	25.59	ENST00000424014.2 ENST00000537073.1	EIF2B1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr1_-_229644034 Show fit	25.36	ENST00000366678.3 ENST00000261396.3 ENST00000537506.1	NUP133 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 133kDa
chr14_+_23776024 Show fit	24.90	ENST00000553781.1 ENST00000556100.1 ENST00000557236.1 ENST00000557579.1	BCL2L2-PABPN1 Links Ensembl NCBI GeneCards UniProt Show fit BCL2L2 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2L2-PABPN1 readthrough BCL2-like 2
chr19_+_10362577 Show fit	24.83	ENST00000592514.1 ENST00000307422.5 ENST00000253099.6 ENST00000590150.1 ENST00000590669.1	MRPL4 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L4
chr2_-_68290106 Show fit	24.64	ENST00000407324.1 ENST00000355848.3 ENST00000409302.1 ENST00000410067.3	C1D Links Ensembl NCBI GeneCards UniProt Show fit	C1D nuclear receptor corepressor
chr11_+_60609537 Show fit	24.60	ENST00000227520.5	CCDC86 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 86
chr2_+_114195268 Show fit	24.55	ENST00000259199.4 ENST00000416503.2 ENST00000433343.2	CBWD2 Links Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 2
chr3_+_141457030 Show fit	24.47	ENST00000273480.3	RNF7 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 7
chr12_-_120884175 Show fit	24.40	ENST00000546954.1	TRIAP1 Links Ensembl NCBI GeneCards UniProt Show fit	TP53 regulated inhibitor of apoptosis 1
chr17_-_685493 Show fit	24.38	ENST00000536578.1 ENST00000301328.5 ENST00000576419.1	GLOD4 Links Ensembl NCBI GeneCards UniProt Show fit	glyoxalase domain containing 4
chr3_-_196669298 Show fit	23.77	ENST00000411704.1 ENST00000452404.2	NCBP2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear cap binding protein subunit 2, 20kDa
chr15_-_66790146 Show fit	23.76	ENST00000316634.5	SNAPC5 Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear RNA activating complex, polypeptide 5, 19kDa
chr9_-_70490107 Show fit	23.45	ENST00000377395.4 ENST00000429800.2 ENST00000430059.2 ENST00000377384.1 ENST00000382405.3	CBWD5 Links Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 5
chr2_-_242626127 Show fit	23.20	ENST00000445261.1	DTYMK Links Ensembl NCBI GeneCards UniProt Show fit	deoxythymidylate kinase (thymidylate kinase)
chr2_-_240964716 Show fit	23.19	ENST00000404554.1 ENST00000407129.3 ENST00000307300.4 ENST00000443626.1 ENST00000252711.2	NDUFA10 Links Ensembl NCBI GeneCards UniProt Show fit	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr3_-_196669248 Show fit	23.08	ENST00000447325.1	NCBP2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear cap binding protein subunit 2, 20kDa
chr1_-_115259337 Show fit	22.96	ENST00000369535.4	NRAS Links Ensembl NCBI GeneCards UniProt Show fit	neuroblastoma RAS viral (v-ras) oncogene homolog
chr13_+_103249322 Show fit	22.82	ENST00000376065.4 ENST00000376052.3	TPP2 Links Ensembl NCBI GeneCards UniProt Show fit	tripeptidyl peptidase II
chr17_+_57642886 Show fit	22.28	ENST00000251241.4 ENST00000451169.2 ENST00000425628.3 ENST00000584385.1 ENST00000580030.1	DHX40 Links Ensembl NCBI GeneCards UniProt Show fit	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr9_-_32573130 Show fit	22.07	ENST00000350021.2 ENST00000379847.3	NDUFB6 Links Ensembl NCBI GeneCards UniProt Show fit	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr12_+_69633407 Show fit	21.87	ENST00000551516.1	CPSF6 Links Ensembl NCBI GeneCards UniProt Show fit	cleavage and polyadenylation specific factor 6, 68kDa
chr4_+_113558272 Show fit	21.68	ENST00000509061.1 ENST00000508577.1 ENST00000513553.1	LARP7 Links Ensembl NCBI GeneCards UniProt Show fit	La ribonucleoprotein domain family, member 7
chr22_+_20105259 Show fit	21.64	ENST00000416427.1 ENST00000421656.1 ENST00000423859.1 ENST00000418705.2	RANBP1 Links Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 1
chr16_-_3767506 Show fit	21.21	ENST00000538171.1	TRAP1 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor-associated protein 1
chr17_+_73663402 Show fit	21.13	ENST00000355423.3	SAP30BP Links Ensembl NCBI GeneCards UniProt Show fit	SAP30 binding protein
chr1_+_147400506 Show fit	20.51	ENST00000314163.7 ENST00000468618.2	GPR89B Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 89B
chr17_-_47022140 Show fit	20.32	ENST00000290330.3	SNF8 Links Ensembl NCBI GeneCards UniProt Show fit	SNF8, ESCRT-II complex subunit
chr9_+_70856397 Show fit	20.30	ENST00000360171.6	CBWD3 Links Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 3
chr3_-_52443799 Show fit	20.22	ENST00000470173.1 ENST00000296288.5	BAP1 Links Ensembl NCBI GeneCards UniProt Show fit	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chrX_-_153285251 Show fit	20.05	ENST00000444230.1 ENST00000393682.1 ENST00000393687.2 ENST00000429936.2 ENST00000369974.2	IRAK1 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin-1 receptor-associated kinase 1
chrX_-_47518498 Show fit	19.86	ENST00000335890.2	UXT Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitously-expressed, prefoldin-like chaperone
chr16_-_3767551 Show fit	19.82	ENST00000246957.5	TRAP1 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor-associated protein 1
chr21_-_44527613 Show fit	19.76	ENST00000380276.2 ENST00000398137.1 ENST00000291552.4	U2AF1 Links Ensembl NCBI GeneCards UniProt Show fit	U2 small nuclear RNA auxiliary factor 1
chr11_-_126138808 Show fit	19.74	ENST00000332118.6 ENST00000532259.1	SRPR Links Ensembl NCBI GeneCards UniProt Show fit	signal recognition particle receptor (docking protein)
chr9_-_33001520 Show fit	19.53	ENST00000463596.1 ENST00000379819.1 ENST00000397172.3 ENST00000379812.5 ENST00000477119.1 ENST00000379813.3 ENST00000379825.2 ENST00000309615.3 ENST00000476858.1 ENST00000473221.1	APTX Links Ensembl NCBI GeneCards UniProt Show fit	aprataxin
chr22_+_20105012 Show fit	19.37	ENST00000331821.3 ENST00000411892.1	RANBP1 Links Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 1
chr3_+_141457105 Show fit	19.34	ENST00000480908.1 ENST00000393000.3	RNF7 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 7
chr12_+_7079944 Show fit	19.21	ENST00000261406.6	EMG1 Links Ensembl NCBI GeneCards UniProt Show fit	EMG1 N1-specific pseudouridine methyltransferase
chr7_+_23145347 Show fit	19.07	ENST00000322231.7	KLHL7 Links Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 7
chr19_+_54619125 Show fit	18.88	ENST00000445811.1 ENST00000419967.1 ENST00000445124.1 ENST00000447810.1	PRPF31 Links Ensembl NCBI GeneCards UniProt Show fit	pre-mRNA processing factor 31
chrX_+_24072833 Show fit	18.74	ENST00000253039.4	EIF2S3 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr3_-_45017609 Show fit	18.70	ENST00000342790.4 ENST00000424952.2 ENST00000296127.3 ENST00000455235.1	ZDHHC3 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger, DHHC-type containing 3
chr12_-_58165870 Show fit	18.64	ENST00000257848.7	METTL1 Links Ensembl NCBI GeneCards UniProt Show fit	methyltransferase like 1
chr6_-_144416737 Show fit	18.19	ENST00000367569.2	SF3B5 Links Ensembl NCBI GeneCards UniProt Show fit	splicing factor 3b, subunit 5, 10kDa
chrX_-_47518527 Show fit	18.08	ENST00000333119.3	UXT Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitously-expressed, prefoldin-like chaperone
chr1_-_36107445 Show fit	17.93	ENST00000373237.3	PSMB2 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, beta type, 2
chr4_-_39367949 Show fit	17.80	ENST00000503784.1 ENST00000349703.2 ENST00000381897.1	RFC1 Links Ensembl NCBI GeneCards UniProt Show fit	replication factor C (activator 1) 1, 145kDa
chr7_+_23145366 Show fit	17.79	ENST00000339077.5 ENST00000322275.5 ENST00000539124.1 ENST00000542558.1	KLHL7 Links Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 7
chr17_+_73663470 Show fit	17.76	ENST00000583536.1	SAP30BP Links Ensembl NCBI GeneCards UniProt Show fit	SAP30 binding protein
chr19_+_10362882 Show fit	17.73	ENST00000393733.2 ENST00000588502.1	MRPL4 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L4
chr5_-_133304473 Show fit	17.55	ENST00000231512.3	C5orf15 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 5 open reading frame 15
chr1_+_186344945 Show fit	17.50	ENST00000419367.3 ENST00000287859.6	C1orf27 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 27
chr1_+_186344883 Show fit	17.26	ENST00000367470.3	C1orf27 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 27
chr11_+_34127142 Show fit	17.08	ENST00000257829.3 ENST00000531159.2	NAT10 Links Ensembl NCBI GeneCards UniProt Show fit	N-acetyltransferase 10 (GCN5-related)
chr12_+_108079509 Show fit	17.03	ENST00000412830.3 ENST00000547995.1	PWP1 Links Ensembl NCBI GeneCards UniProt Show fit	PWP1 homolog (S. cerevisiae)
chr8_-_126103969 Show fit	16.82	ENST00000517845.1	KIAA0196 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0196
chr15_+_80351910 Show fit	16.77	ENST00000261749.6 ENST00000561060.1	ZFAND6 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger, AN1-type domain 6
chr1_-_220220000 Show fit	16.76	ENST00000366923.3	EPRS Links Ensembl NCBI GeneCards UniProt Show fit	glutamyl-prolyl-tRNA synthetase
chr12_-_46384334 Show fit	16.67	ENST00000369367.3 ENST00000266589.6 ENST00000395453.2 ENST00000395454.2	SCAF11 Links Ensembl NCBI GeneCards UniProt Show fit	SR-related CTD-associated factor 11
chr19_-_5719860 Show fit	16.44	ENST00000590729.1	LONP1 Links Ensembl NCBI GeneCards UniProt Show fit	lon peptidase 1, mitochondrial
chr8_-_126104055 Show fit	16.37	ENST00000318410.7	KIAA0196 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0196
chr16_-_20753114 Show fit	15.96	ENST00000396083.2	THUMPD1 Links Ensembl NCBI GeneCards UniProt Show fit	THUMP domain containing 1
chr2_-_130939115 Show fit	15.95	ENST00000441135.1 ENST00000339679.7 ENST00000426662.2 ENST00000443958.2 ENST00000351288.6 ENST00000453750.1 ENST00000452225.2	SMPD4 Links Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chr20_+_55043647 Show fit	15.90	ENST00000023939.4 ENST00000395881.3 ENST00000357348.5 ENST00000449062.1 ENST00000435342.2	RTFDC1 Links Ensembl NCBI GeneCards UniProt Show fit	replication termination factor 2 domain containing 1
chr15_+_80351977 Show fit	15.86	ENST00000559157.1 ENST00000561012.1 ENST00000564367.1 ENST00000558494.1	ZFAND6 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger, AN1-type domain 6
chr2_-_3606206 Show fit	15.75	ENST00000315212.3	RNASEH1 Links Ensembl NCBI GeneCards UniProt Show fit	ribonuclease H1
chr3_-_196669371 Show fit	15.64	ENST00000427641.2 ENST00000321256.5	NCBP2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear cap binding protein subunit 2, 20kDa
chr17_+_33914460 Show fit	15.61	ENST00000537622.2	AP2B1 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor-related protein complex 2, beta 1 subunit
chr17_+_685513 Show fit	15.17	ENST00000304478.4	RNMTL1 Links Ensembl NCBI GeneCards UniProt Show fit	RNA methyltransferase like 1
chr9_+_114393634 Show fit	15.07	ENST00000556107.1 ENST00000374294.3	DNAJC25 Links Ensembl NCBI GeneCards UniProt Show fit DNAJC25-GNG10 Links Ensembl NCBI GeneCards UniProt Show fit	DnaJ (Hsp40) homolog, subfamily C , member 25 DNAJC25-GNG10 readthrough
chr1_-_32110467 Show fit	15.00	ENST00000440872.2 ENST00000373703.4	PEF1 Links Ensembl NCBI GeneCards UniProt Show fit	penta-EF-hand domain containing 1
chr7_+_23221613 Show fit	14.99	ENST00000410002.3 ENST00000413919.1	NUPL2 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin like 2
chr17_+_33914276 Show fit	14.99	ENST00000592545.1 ENST00000538556.1 ENST00000312678.8 ENST00000589344.1	AP2B1 Links Ensembl NCBI GeneCards UniProt Show fit	adaptor-related protein complex 2, beta 1 subunit
chr8_+_101162812 Show fit	14.98	ENST00000353107.3 ENST00000522439.1	POLR2K Links Ensembl NCBI GeneCards UniProt Show fit	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr4_+_122722466 Show fit	14.85	ENST00000243498.5 ENST00000379663.3 ENST00000509800.1	EXOSC9 Links Ensembl NCBI GeneCards UniProt Show fit	exosome component 9
chr5_-_179233934 Show fit	14.48	ENST00000292591.7	MGAT4B Links Ensembl NCBI GeneCards UniProt Show fit	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr6_+_41755389 Show fit	14.27	ENST00000398884.3 ENST00000398881.3	TOMM6 Links Ensembl NCBI GeneCards UniProt Show fit	translocase of outer mitochondrial membrane 6 homolog (yeast)
chr17_+_40985407 Show fit	14.14	ENST00000586114.1 ENST00000590720.1 ENST00000585805.1 ENST00000541124.1 ENST00000441946.2 ENST00000591152.1 ENST00000589469.1 ENST00000293362.3 ENST00000592169.1	PSME3 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr9_-_134955246 Show fit	13.94	ENST00000357028.2 ENST00000474263.1 ENST00000292035.5	MED27 Links Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 27
chr3_-_101405539 Show fit	13.90	ENST00000469605.1 ENST00000495401.1 ENST00000394077.3	RPL24 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L24
chr14_+_61447927 Show fit	13.89	ENST00000451406.1	SLC38A6 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38, member 6
chr22_+_26879817 Show fit	13.82	ENST00000215917.7	SRRD Links Ensembl NCBI GeneCards UniProt Show fit	SRR1 domain containing
chr7_+_23221438 Show fit	13.61	ENST00000258742.5	NUPL2 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin like 2
chr11_-_66112555 Show fit	13.53	ENST00000425825.2 ENST00000359957.3	BRMS1 Links Ensembl NCBI GeneCards UniProt Show fit	breast cancer metastasis suppressor 1
chr8_+_133787586 Show fit	13.50	ENST00000395379.1 ENST00000395386.2 ENST00000337920.4	PHF20L1 Links Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 20-like 1
chr6_-_34855773 Show fit	13.46	ENST00000420584.2 ENST00000361288.4	TAF11 Links Ensembl NCBI GeneCards UniProt Show fit	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
chr4_-_74124502 Show fit	13.44	ENST00000358602.4 ENST00000330838.6 ENST00000561029.1	ANKRD17 Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 17
chr4_-_146019335 Show fit	13.40	ENST00000451299.2 ENST00000507656.1 ENST00000309439.5	ANAPC10 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 10
chr16_+_19079215 Show fit	13.10	ENST00000544894.2 ENST00000561858.1	COQ7 Links Ensembl NCBI GeneCards UniProt Show fit	coenzyme Q7 homolog, ubiquinone (yeast)
chr7_-_93633658 Show fit	13.00	ENST00000433727.1	BET1 Links Ensembl NCBI GeneCards UniProt Show fit	Bet1 golgi vesicular membrane trafficking protein
chr1_-_154600421 Show fit	12.96	ENST00000368471.3 ENST00000292205.5	ADAR Links Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase, RNA-specific
chr7_-_93633684 Show fit	12.87	ENST00000222547.3 ENST00000425626.1	BET1 Links Ensembl NCBI GeneCards UniProt Show fit	Bet1 golgi vesicular membrane trafficking protein
chr1_+_45241109 Show fit	12.54	ENST00000396651.3	RPS8 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S8
chr16_+_70380732 Show fit	12.14	ENST00000302243.7	DDX19A Links Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
chr12_+_64173888 Show fit	11.85	ENST00000537373.1	TMEM5 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 5
chr2_+_130939235 Show fit	11.83	ENST00000425361.1 ENST00000457492.1	MZT2B Links Ensembl NCBI GeneCards UniProt Show fit	mitotic spindle organizing protein 2B
chr4_-_146019287 Show fit	10.53	ENST00000502847.1 ENST00000513054.1	ANAPC10 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 10
chr11_+_57480046 Show fit	10.41	ENST00000378312.4 ENST00000278422.4	TMX2 Links Ensembl NCBI GeneCards UniProt Show fit	thioredoxin-related transmembrane protein 2
chr16_+_1359511 Show fit	10.17	ENST00000397514.3 ENST00000397515.2 ENST00000567383.1 ENST00000403747.2 ENST00000566587.1	UBE2I Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-conjugating enzyme E2I
chr6_+_37400974 Show fit	10.11	ENST00000455891.1 ENST00000373451.4	CMTR1 Links Ensembl NCBI GeneCards UniProt Show fit	cap methyltransferase 1
chr1_+_45241186 Show fit	10.08	ENST00000372209.3	RPS8 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S8
chr19_-_19030157 Show fit	10.02	ENST00000349893.4 ENST00000351079.4 ENST00000600932.1 ENST00000262812.4	COPE Links Ensembl NCBI GeneCards UniProt Show fit	coatomer protein complex, subunit epsilon
chr12_-_58240470 Show fit	10.01	ENST00000548823.1 ENST00000398073.2	CTDSP2 Links Ensembl NCBI GeneCards UniProt Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_-_220219775 Show fit	9.89	ENST00000609181.1	EPRS Links Ensembl NCBI GeneCards UniProt Show fit	glutamyl-prolyl-tRNA synthetase
chr12_-_44200052 Show fit	9.70	ENST00000548315.1 ENST00000552521.1 ENST00000546662.1 ENST00000548403.1 ENST00000546506.1	TWF1 Links Ensembl NCBI GeneCards UniProt Show fit	twinfilin actin-binding protein 1
chr9_+_140083099 Show fit	9.64	ENST00000322310.5	SSNA1 Links Ensembl NCBI GeneCards UniProt Show fit	Sjogren syndrome nuclear autoantigen 1
chr4_-_146019693 Show fit	9.51	ENST00000514390.1	ANAPC10 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 10
chr4_-_4543700 Show fit	9.45	ENST00000505286.1 ENST00000306200.2	STX18 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin 18
chr8_-_145743164 Show fit	9.30	ENST00000428558.2	RECQL4 Links Ensembl NCBI GeneCards UniProt Show fit	RecQ protein-like 4
chr1_+_7831323 Show fit	9.24	ENST00000054666.6	VAMP3 Links Ensembl NCBI GeneCards UniProt Show fit	vesicle-associated membrane protein 3
chr12_+_64173583 Show fit	8.82	ENST00000261234.6	TMEM5 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 5
chr16_-_2318373 Show fit	8.79	ENST00000566458.1 ENST00000320225.5	RNPS1 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding protein S1, serine-rich domain
chr6_-_114292284 Show fit	8.77	ENST00000520895.1 ENST00000521163.1 ENST00000524334.1 ENST00000368632.2 ENST00000398283.2	HDAC2 Links Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 2
chr20_-_5093503 Show fit	8.71	ENST00000379277.2	TMEM230 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 230
chr11_-_62572901 Show fit	8.69	ENST00000439713.2 ENST00000531131.1 ENST00000530875.1 ENST00000531709.2 ENST00000294172.2	NXF1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear RNA export factor 1
chr2_+_96068436 Show fit	8.58	ENST00000445649.1 ENST00000447036.1 ENST00000233379.4 ENST00000418606.1	FAHD2A Links Ensembl NCBI GeneCards UniProt Show fit	fumarylacetoacetate hydrolase domain containing 2A
chr15_-_23034322 Show fit	8.55	ENST00000539711.2 ENST00000560039.1 ENST00000398013.3 ENST00000337451.3 ENST00000359727.4 ENST00000398014.2	NIPA2 Links Ensembl NCBI GeneCards UniProt Show fit	non imprinted in Prader-Willi/Angelman syndrome 2
chr1_-_37980344 Show fit	8.44	ENST00000448519.2 ENST00000373075.2 ENST00000373073.4 ENST00000296214.5	MEAF6 Links Ensembl NCBI GeneCards UniProt Show fit	MYST/Esa1-associated factor 6
chr16_+_29827832 Show fit	8.38	ENST00000609618.1	PAGR1 Links Ensembl NCBI GeneCards UniProt Show fit	PAXIP1-associated glutamate-rich protein 1
chr16_+_70380825 Show fit	8.14	ENST00000417604.2	DDX19A Links Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
chr8_-_37756972 Show fit	7.97	ENST00000330843.4 ENST00000522727.1 ENST00000287263.4	RAB11FIP1 Links Ensembl NCBI GeneCards UniProt Show fit	RAB11 family interacting protein 1 (class I)
chr6_-_106773291 Show fit	7.82	ENST00000343245.3	ATG5 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 5
chr7_+_44646218 Show fit	7.81	ENST00000444676.1 ENST00000222673.5	OGDH Links Ensembl NCBI GeneCards UniProt Show fit	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr16_+_1359138 Show fit	7.63	ENST00000325437.5	UBE2I Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-conjugating enzyme E2I
chr11_+_67195917 Show fit	7.59	ENST00000524934.1 ENST00000539188.1 ENST00000312629.5	RPS6KB2 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase, 70kDa, polypeptide 2
chr11_-_64889529 Show fit	7.59	ENST00000531743.1 ENST00000527548.1 ENST00000526555.1 ENST00000279259.3	FAU Links Ensembl NCBI GeneCards UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr19_+_36119929 Show fit	7.47	ENST00000588161.1 ENST00000262633.4 ENST00000592202.1 ENST00000586618.1	RBM42 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 42
chr11_+_64889773 Show fit	7.44	ENST00000534078.1 ENST00000526171.1 ENST00000279242.2 ENST00000531705.1 ENST00000533943.1	MRPL49 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L49
chr6_-_106773491 Show fit	7.22	ENST00000360666.4	ATG5 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 5
chr6_+_20403997 Show fit	7.11	ENST00000535432.1	E2F3 Links Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 3
chr3_+_113775576 Show fit	7.08	ENST00000485050.1 ENST00000281273.4	QTRTD1 Links Ensembl NCBI GeneCards UniProt Show fit	queuine tRNA-ribosyltransferase domain containing 1
chr6_-_106773610 Show fit	7.07	ENST00000369076.3 ENST00000369070.1	ATG5 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 5
chr6_+_41888926 Show fit	6.99	ENST00000230340.4	BYSL Links Ensembl NCBI GeneCards UniProt Show fit	bystin-like
chr16_+_29827285 Show fit	6.74	ENST00000320330.6	PAGR1 Links Ensembl NCBI GeneCards UniProt Show fit	PAXIP1 associated glutamate-rich protein 1
chr12_-_132628847 Show fit	6.46	ENST00000397333.3	DDX51 Links Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr19_+_36120009 Show fit	6.33	ENST00000589871.1	RBM42 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 42
chr14_+_61447832 Show fit	6.10	ENST00000354886.2 ENST00000267488.4	SLC38A6 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38, member 6
chr5_-_74807418 Show fit	6.10	ENST00000405807.4 ENST00000261415.7	COL4A3BP Links Ensembl NCBI GeneCards UniProt Show fit	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr1_-_186344456 Show fit	6.05	ENST00000367478.4	TPR Links Ensembl NCBI GeneCards UniProt Show fit	translocated promoter region, nuclear basket protein
chr7_-_150924121 Show fit	6.01	ENST00000441774.1 ENST00000222388.2 ENST00000287844.2	ABCF2 Links Ensembl NCBI GeneCards UniProt Show fit	ATP-binding cassette, sub-family F (GCN20), member 2
chr1_+_110527308 Show fit	5.84	ENST00000369799.5	AHCYL1 Links Ensembl NCBI GeneCards UniProt Show fit	adenosylhomocysteinase-like 1
chr11_-_67276100 Show fit	5.61	ENST00000301488.3	CDK2AP2 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin-dependent kinase 2 associated protein 2
chr4_-_39460520 Show fit	5.58	ENST00000503040.1 ENST00000504470.1 ENST00000508595.1 ENST00000295955.9	RPL9 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L9
chr11_+_18344106 Show fit	5.54	ENST00000534641.1 ENST00000525831.1 ENST00000265963.4	GTF2H1 Links Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIH, polypeptide 1, 62kDa
chr16_+_19078960 Show fit	5.54	ENST00000568985.1 ENST00000566110.1	COQ7 Links Ensembl NCBI GeneCards UniProt Show fit	coenzyme Q7 homolog, ubiquinone (yeast)
chr8_+_37594130 Show fit	5.53	ENST00000518526.1 ENST00000523887.1 ENST00000276461.5	ERLIN2 Links Ensembl NCBI GeneCards UniProt Show fit	ER lipid raft associated 2
chr6_-_90062543 Show fit	5.52	ENST00000435041.2	UBE2J1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-conjugating enzyme E2, J1
chr16_+_70332956 Show fit	5.39	ENST00000288071.6 ENST00000393657.2 ENST00000355992.3 ENST00000567706.1	DDX19B Links Ensembl NCBI GeneCards UniProt Show fit RP11-529K1.3 Links Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B Uncharacterized protein
chr16_+_2022036 Show fit	5.35	ENST00000568546.1	TBL3 Links Ensembl NCBI GeneCards UniProt Show fit	transducin (beta)-like 3
chr15_-_73076030 Show fit	5.30	ENST00000311669.8	ADPGK Links Ensembl NCBI GeneCards UniProt Show fit	ADP-dependent glucokinase
chr21_+_45079409 Show fit	5.15	ENST00000340648.4	RRP1B Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal RNA processing 1B
chr14_+_32030582 Show fit	4.95	ENST00000550649.1 ENST00000281081.7	NUBPL Links Ensembl NCBI GeneCards UniProt Show fit	nucleotide binding protein-like
chr11_+_18343800 Show fit	4.84	ENST00000453096.2	GTF2H1 Links Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIH, polypeptide 1, 62kDa
chr3_+_185304059 Show fit	4.83	ENST00000427465.2	SENP2 Links Ensembl NCBI GeneCards UniProt Show fit	SUMO1/sentrin/SMT3 specific peptidase 2
chr3_+_11314099 Show fit	4.70	ENST00000446450.2 ENST00000354956.5 ENST00000354449.3 ENST00000419112.1	ATG7 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 7
chr14_+_31091511 Show fit	4.50	ENST00000544052.2 ENST00000421551.3 ENST00000541123.1 ENST00000557076.1 ENST00000553693.1 ENST00000396629.2	SCFD1 Links Ensembl NCBI GeneCards UniProt Show fit	sec1 family domain containing 1
chr4_-_39460496 Show fit	4.47	ENST00000449470.2	RPL9 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L9
chr11_-_10562710 Show fit	4.34	ENST00000528665.1 ENST00000265981.2	RNF141 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 141
chr11_-_64889649 Show fit	4.25	ENST00000434372.2	FAU Links Ensembl NCBI GeneCards UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr8_+_21946681 Show fit	4.25	ENST00000289921.7	FAM160B2 Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 160, member B2
chr3_+_185303962 Show fit	3.85	ENST00000296257.5	SENP2 Links Ensembl NCBI GeneCards UniProt Show fit	SUMO1/sentrin/SMT3 specific peptidase 2
chr2_+_109335929 Show fit	3.81	ENST00000283195.6	RANBP2 Links Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 2
chr17_-_36981556 Show fit	3.72	ENST00000536127.1 ENST00000225428.5	CWC25 Links Ensembl NCBI GeneCards UniProt Show fit	CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr17_-_49198095 Show fit	3.70	ENST00000505279.1	SPAG9 Links Ensembl NCBI GeneCards UniProt Show fit	sperm associated antigen 9
chr19_+_36119975 Show fit	3.68	ENST00000589559.1 ENST00000360475.4	RBM42 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 42
chr12_+_120884222 Show fit	3.66	ENST00000551765.1 ENST00000229384.5	GATC Links Ensembl NCBI GeneCards UniProt Show fit	glutamyl-tRNA(Gln) amidotransferase, subunit C
chr11_-_64889252 Show fit	3.61	ENST00000525297.1 ENST00000529259.1	FAU Links Ensembl NCBI GeneCards UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr17_-_37009882 Show fit	3.55	ENST00000378096.3 ENST00000394332.1 ENST00000394333.1 ENST00000577407.1 ENST00000479035.2	RPL23 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L23
chr4_-_76439483 Show fit	3.43	ENST00000380840.2 ENST00000513257.1 ENST00000507014.1	RCHY1 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr15_+_63481668 Show fit	3.41	ENST00000321437.4 ENST00000559006.1 ENST00000448330.2	RAB8B Links Ensembl NCBI GeneCards UniProt Show fit	RAB8B, member RAS oncogene family
chr1_+_12040238 Show fit	3.40	ENST00000444836.1 ENST00000235329.5	MFN2 Links Ensembl NCBI GeneCards UniProt Show fit	mitofusin 2
chr19_+_58341656 Show fit	3.33	ENST00000442832.4 ENST00000594901.1	ZNF587B Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 587B
chr5_-_132113083 Show fit	3.23	ENST00000296873.7	SEPT8 Links Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr2_+_119981384 Show fit	3.20	ENST00000393108.2 ENST00000354888.5 ENST00000450943.2 ENST00000393110.2 ENST00000393106.2 ENST00000409811.1 ENST00000393107.2	STEAP3 Links Ensembl NCBI GeneCards UniProt Show fit	STEAP family member 3, metalloreductase
chr8_-_119124045 Show fit	3.12	ENST00000378204.2	EXT1 Links Ensembl NCBI GeneCards UniProt Show fit	exostosin glycosyltransferase 1
chr9_-_94877658 Show fit	2.89	ENST00000262554.2 ENST00000337841.4	SPTLC1 Links Ensembl NCBI GeneCards UniProt Show fit	serine palmitoyltransferase, long chain base subunit 1

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
20.8	62.4	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
17.0	68.1	GO:0034476	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
16.4	115.0	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
15.6	62.5	GO:0046833	snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
10.3	41.0	GO:0009386	translational attenuation(GO:0009386)
9.7	29.2	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
8.6	25.9	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
7.4	22.1	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
6.8	20.3	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
6.7	20.2	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
6.6	46.4	GO:0060011	Sertoli cell proliferation(GO:0060011)
6.3	25.4	GO:0031081	nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
6.1	30.6	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
5.8	23.2	GO:0009189	dTTP biosynthetic process(GO:0006235) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
5.7	17.1	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
5.7	17.1	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
5.2	15.7	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
4.5	67.4	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
3.7	25.9	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
3.5	13.9	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
3.4	23.6	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
3.4	13.4	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
3.1	18.9	GO:0048254	snoRNA localization(GO:0048254)
2.8	28.3	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
2.7	43.8	GO:0045116	protein neddylation(GO:0045116)
2.7	24.4	GO:2001138	regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
2.5	10.1	GO:0080009	mRNA methylation(GO:0080009)
2.5	50.2	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
2.4	9.6	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
2.4	12.0	GO:0030047	actin modification(GO:0030047)
2.4	19.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
2.4	19.2	GO:0070475	rRNA base methylation(GO:0070475)
2.2	19.5	GO:0000012	single strand break repair(GO:0000012)
2.1	15.0	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
2.1	8.4	GO:0043983	histone H4-K12 acetylation(GO:0043983)
2.0	6.1	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
2.0	6.1	GO:0006404	RNA import into nucleus(GO:0006404)
1.9	20.7	GO:0035269	protein O-linked mannosylation(GO:0035269)
1.8	69.1	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
1.8	16.0	GO:0006685	sphingomyelin catabolic process(GO:0006685)
1.8	8.8	GO:0061198	fungiform papilla formation(GO:0061198)
1.7	37.9	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
1.6	9.5	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
1.6	4.7	GO:0090298	late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) single-organism membrane invagination(GO:1902534)
1.5	9.2	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
1.4	15.9	GO:1902969	mitotic DNA replication(GO:1902969)
1.4	104.3	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
1.4	36.0	GO:0072663	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
1.4	5.5	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.3	60.2	GO:0006378	mRNA polyadenylation(GO:0006378)
1.3	17.8	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
1.2	24.6	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
1.2	13.5	GO:2000210	positive regulation of anoikis(GO:2000210)
1.2	18.7	GO:0018345	protein palmitoylation(GO:0018345)
1.1	8.0	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
1.1	5.6	GO:2000035	regulation of stem cell division(GO:2000035)
1.1	8.7	GO:0016926	protein desumoylation(GO:0016926)
1.1	8.6	GO:0015693	magnesium ion transport(GO:0015693)
1.0	70.9	GO:0031124	mRNA 3'-end processing(GO:0031124)
1.0	16.0	GO:0000154	rRNA modification(GO:0000154)
1.0	2.0	GO:0000965	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) mitochondrial RNA 3'-end processing(GO:0000965)
0.9	48.3	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.9	2.8	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.9	3.6	GO:0072716	response to actinomycin D(GO:0072716) cellular response to actinomycin D(GO:0072717)
0.8	9.3	GO:0000733	DNA strand renaturation(GO:0000733)
0.8	21.2	GO:0070987	error-free translesion synthesis(GO:0070987)
0.8	15.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.8	17.5	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.8	5.5	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.8	4.5	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.7	22.5	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.7	30.9	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.7	8.7	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.7	2.9	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.7	7.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.7	45.3	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.7	30.1	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.6	13.5	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.6	3.2	GO:0098706	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.6	18.4	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.5	14.5	GO:0006491	N-glycan processing(GO:0006491)
0.5	30.3	GO:0043039	amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.5	15.0	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.5	5.3	GO:2000111	senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.5	1.9	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.5	25.6	GO:0014003	oligodendrocyte development(GO:0014003)
0.4	25.9	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.4	1.2	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.4	32.1	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.4	10.0	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.3	29.6	GO:0010942	positive regulation of cell death(GO:0010942)
0.3	12.6	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.3	3.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3	20.0	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.3	7.6	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.3	16.7	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.3	3.4	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.3	2.8	GO:0061635	regulation of protein complex stability(GO:0061635)
0.2	4.9	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2	35.1	GO:0046718	viral entry into host cell(GO:0046718)
0.2	1.2	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.1	10.4	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	5.3	GO:0061621	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1	10.0	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.1	6.4	GO:0016236	macroautophagy(GO:0016236)
0.1	1.1	GO:0033623	regulation of integrin activation(GO:0033623)
0.1	5.2	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.1	14.7	GO:0000398	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	8.8	GO:0006413	translational initiation(GO:0006413)
0.0	10.7	GO:0048511	rhythmic process(GO:0048511)
0.0	1.4	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
25.5	102.1	GO:0042025	host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
15.6	62.5	GO:0005846	nuclear cap binding complex(GO:0005846)
14.6	43.8	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
13.5	67.4	GO:0032021	NELF complex(GO:0032021)
11.4	34.1	GO:0030689	Noc complex(GO:0030689)
10.0	50.2	GO:0045323	interleukin-1 receptor complex(GO:0045323)
8.4	92.7	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
7.4	66.4	GO:0072546	ER membrane protein complex(GO:0072546)
6.7	53.3	GO:0042382	paraspeckles(GO:0042382)
6.2	18.7	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
4.0	19.8	GO:0089701	U2AF(GO:0089701)
3.8	26.6	GO:0097452	GAIT complex(GO:0097452)
3.8	26.4	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
3.7	22.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
3.7	25.6	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
3.6	46.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
3.4	10.1	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
2.6	104.3	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
2.6	13.0	GO:0044530	supraspliceosomal complex(GO:0044530)
2.5	17.8	GO:0005663	DNA replication factor C complex(GO:0005663)
2.4	14.1	GO:0008537	proteasome activator complex(GO:0008537)
2.1	25.4	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
2.0	14.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
1.9	50.6	GO:0035145	exon-exon junction complex(GO:0035145)
1.8	49.8	GO:0000930	gamma-tubulin complex(GO:0000930)
1.6	30.6	GO:0036020	endolysosome membrane(GO:0036020)
1.4	37.1	GO:0071011	precatalytic spliceosome(GO:0071011)
1.4	15.1	GO:0044666	MLL3/4 complex(GO:0044666)
1.2	18.6	GO:0042405	nuclear inclusion body(GO:0042405)
1.1	17.9	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
1.1	5.3	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.0	30.1	GO:0005680	anaphase-promoting complex(GO:0005680)
1.0	67.3	GO:0030684	preribosome(GO:0030684)
1.0	10.0	GO:0030126	COPI vesicle coat(GO:0030126)
0.9	88.6	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.8	20.3	GO:0036452	ESCRT complex(GO:0036452)
0.8	8.4	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.8	22.3	GO:0070822	Sin3-type complex(GO:0070822)
0.8	45.3	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.8	2.3	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.8	27.8	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.7	2.9	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.7	49.1	GO:0031201	SNARE complex(GO:0031201)
0.7	44.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.6	17.8	GO:0000795	synaptonemal complex(GO:0000795)
0.6	15.0	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.6	63.0	GO:0005643	nuclear pore(GO:0005643)
0.5	6.0	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.5	5.3	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.5	2.8	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.4	3.4	GO:0051286	cell tip(GO:0051286)
0.4	19.1	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3	20.2	GO:0031519	PcG protein complex(GO:0031519)
0.3	15.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.3	17.8	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.2	23.0	GO:0070821	tertiary granule membrane(GO:0070821)
0.2	3.4	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.2	2.8	GO:0044754	autolysosome(GO:0044754)
0.2	1.4	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	8.0	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	12.3	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	24.7	GO:0005802	trans-Golgi network(GO:0005802)
0.1	9.6	GO:0036064	ciliary basal body(GO:0036064)
0.1	9.9	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	1.0	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	12.0	GO:0030175	filopodium(GO:0030175)
0.1	11.9	GO:0005681	spliceosomal complex(GO:0005681)
0.1	34.7	GO:0016607	nuclear speck(GO:0016607)
0.1	45.8	GO:0000139	Golgi membrane(GO:0000139)
0.1	4.7	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1	19.4	GO:0000790	nuclear chromatin(GO:0000790)
0.1	10.8	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.1	6.8	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	6.4	GO:0019866	mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0	7.0	GO:0005667	transcription factor complex(GO:0005667)
0.0	11.7	GO:0005635	nuclear envelope(GO:0005635)
0.0	6.6	GO:0005769	early endosome(GO:0005769)
0.0	9.2	GO:0045177	apical part of cell(GO:0045177)
0.0	1.1	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	1.2	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	41.3	GO:0070062	extracellular exosome(GO:0070062)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.7	29.2	GO:0004802	transketolase activity(GO:0004802)
7.8	62.5	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
7.2	50.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
5.7	17.1	GO:0070361	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
5.7	102.1	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
5.5	43.8	GO:0019788	NEDD8 transferase activity(GO:0019788)
4.5	17.8	GO:0043398	HLH domain binding(GO:0043398)
4.0	19.8	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
3.9	23.2	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
3.8	22.8	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
3.7	25.9	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
3.7	22.1	GO:0019776	Atg8 ligase activity(GO:0019776)
3.6	68.1	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
3.2	13.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
3.1	15.7	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
2.8	30.9	GO:0005049	nuclear export signal receptor activity(GO:0005049)
2.8	19.5	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
2.7	18.9	GO:0030621	U4 snRNA binding(GO:0030621)
2.5	17.8	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.5	7.6	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
2.5	10.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
2.3	46.4	GO:0051400	BH domain binding(GO:0051400)
2.3	31.9	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
2.2	26.4	GO:0017070	U6 snRNA binding(GO:0017070)
2.2	8.7	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
2.1	19.2	GO:0008649	rRNA methyltransferase activity(GO:0008649)
2.1	14.5	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.0	14.1	GO:0061133	endopeptidase activator activity(GO:0061133)
2.0	10.0	GO:0008420	CTD phosphatase activity(GO:0008420)
1.6	16.0	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
1.6	76.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
1.5	6.1	GO:0097001	ceramide binding(GO:0097001)
1.5	48.3	GO:0008308	voltage-gated anion channel activity(GO:0008308)
1.5	40.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
1.5	26.6	GO:0035613	RNA stem-loop binding(GO:0035613)
1.4	30.6	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.2	18.7	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.2	9.3	GO:0000405	bubble DNA binding(GO:0000405)
1.0	24.6	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
1.0	5.8	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.0	2.9	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.9	37.9	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.9	13.5	GO:0042809	vitamin D receptor binding(GO:0042809)
0.9	3.6	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.9	57.7	GO:0035064	methylated histone binding(GO:0035064)
0.9	45.3	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.8	3.2	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.8	4.7	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.8	3.1	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.7	27.6	GO:0051059	NF-kappaB binding(GO:0051059)
0.7	35.7	GO:0000049	tRNA binding(GO:0000049)
0.7	15.0	GO:0001055	RNA polymerase II activity(GO:0001055)
0.7	8.6	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.7	17.6	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.6	130.9	GO:0003735	structural constituent of ribosome(GO:0003735)
0.6	44.3	GO:0003743	translation initiation factor activity(GO:0003743)
0.5	14.4	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5	33.0	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.4	24.4	GO:0005548	phospholipid transporter activity(GO:0005548)
0.4	18.0	GO:0031593	polyubiquitin binding(GO:0031593)
0.4	18.7	GO:0005484	SNAP receptor activity(GO:0005484)
0.4	15.0	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4	30.4	GO:0019905	syntaxin binding(GO:0019905)
0.4	17.0	GO:0030331	estrogen receptor binding(GO:0030331)
0.3	3.4	GO:0030911	TPR domain binding(GO:0030911)
0.3	3.8	GO:0019789	SUMO transferase activity(GO:0019789)
0.2	5.3	GO:0030515	snoRNA binding(GO:0030515)
0.2	20.0	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.2	66.4	GO:0030246	carbohydrate binding(GO:0030246)
0.2	13.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2	0.6	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2	2.8	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.1	61.4	GO:0045296	cadherin binding(GO:0045296)
0.1	71.0	GO:0003682	chromatin binding(GO:0003682)
0.1	28.7	GO:0061630	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1	20.3	GO:0016247	channel regulator activity(GO:0016247)
0.1	5.5	GO:0015485	cholesterol binding(GO:0015485)
0.1	3.4	GO:0002039	p53 binding(GO:0002039)
0.1	1.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	2.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	8.0	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	22.1	GO:0003924	GTPase activity(GO:0003924)
0.1	1.1	GO:0031005	filamin binding(GO:0031005)
0.0	1.4	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	4.0	GO:0001047	core promoter binding(GO:0001047)
0.0	48.8	GO:0003723	RNA binding(GO:0003723)
0.0	1.0	GO:0070412	R-SMAD binding(GO:0070412)
0.0	58.4	GO:0005524	ATP binding(GO:0005524)
0.0	10.3	GO:0042803	protein homodimerization activity(GO:0042803)
0.0	14.8	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	50.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
1.4	21.6	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
1.0	23.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.7	19.5	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.6	70.8	PID E2F PATHWAY	E2F transcription factor network
0.4	12.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2	17.8	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.2	41.0	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	2.8	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	3.6	PID P53 REGULATION PATHWAY	p53 pathway
0.0	1.9	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.6	68.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
4.2	50.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
3.9	62.5	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.9	102.1	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
1.9	126.9	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
1.8	26.4	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
1.7	28.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.6	23.0	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
1.4	30.6	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
1.4	53.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
1.2	30.1	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
1.0	10.0	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
1.0	34.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.8	20.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.7	26.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.7	52.0	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.7	23.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6	14.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.6	7.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.6	18.2	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.5	45.3	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.5	2.8	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.4	22.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.4	29.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.4	12.9	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3	16.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.3	10.3	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.3	17.9	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.2	36.8	REACTOME TRANSLATION	Genes involved in Translation
0.2	17.8	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.2	2.8	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.2	7.6	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.2	29.2	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.2	13.0	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.1	1.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	5.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	3.2	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	3.1	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	8.8	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	2.0	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	1.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions