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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CTCF_CTCFL

Z-value: 1.31

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Transcription factors associated with CTCF_CTCFL

Gene Symbol Gene ID Gene Info
CTCF
ENSG00000102974.10 CCCTC-binding factor
CTCFL
ENSG00000124092.8 CCCTC-binding factor like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CTCFhg19_v2_chr16_+_67596310_675963530.504.3e-15Click!
CTCFLhg19_v2_chr20_-_56100155_56100163-0.491.6e-14Click!

Activity profile of CTCF_CTCFL motif

Sorted Z-values of CTCF_CTCFL motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_132249955 32.67 ENST00000309451.6
MZT2A
mitotic spindle organizing protein 2A
chr2_+_130939827 30.27 ENST00000409255.1
ENST00000455239.1
MZT2B
mitotic spindle organizing protein 2B
chr12_-_82752565 27.18 ENST00000256151.7
CCDC59
coiled-coil domain containing 59
chr12_+_56618102 24.79 ENST00000267023.4
ENST00000380198.2
ENST00000341463.5
NABP2
nucleic acid binding protein 2
chr1_+_203830703 23.46 ENST00000414487.2
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr10_+_81107216 23.28 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr19_+_41768401 21.74 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr17_-_48474828 20.95 ENST00000576448.1
ENST00000225972.7
LRRC59
leucine rich repeat containing 59
chr4_-_106395135 20.35 ENST00000310267.7
PPA2
pyrophosphatase (inorganic) 2
chr22_+_24204375 20.27 ENST00000433835.3
AP000350.10
Uncharacterized protein
chr19_+_49496705 18.90 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr16_-_66864806 18.76 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr5_+_145826867 18.31 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr1_-_94374946 17.84 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr3_+_172468505 17.62 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
ECT2
epithelial cell transforming sequence 2 oncogene
chr11_-_6704513 16.95 ENST00000532203.1
ENST00000288937.6
MRPL17
mitochondrial ribosomal protein L17
chr2_+_130939235 16.94 ENST00000425361.1
ENST00000457492.1
MZT2B
mitotic spindle organizing protein 2B
chr4_-_106395197 16.77 ENST00000508518.1
ENST00000354147.3
ENST00000432483.2
ENST00000510015.1
ENST00000504028.1
ENST00000348706.5
ENST00000357415.4
ENST00000380004.2
ENST00000341695.5
PPA2
pyrophosphatase (inorganic) 2
chr3_+_172468472 16.61 ENST00000232458.5
ENST00000392692.3
ECT2
epithelial cell transforming sequence 2 oncogene
chr19_+_49496782 15.59 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr12_+_48357340 14.98 ENST00000256686.6
ENST00000549288.1
ENST00000552561.1
ENST00000546749.1
ENST00000552546.1
ENST00000550552.1
TMEM106C
transmembrane protein 106C
chr7_+_141438118 14.82 ENST00000265304.6
ENST00000498107.1
ENST00000467681.1
ENST00000465582.1
ENST00000463093.1
SSBP1
single-stranded DNA binding protein 1, mitochondrial
chr8_-_90996837 14.74 ENST00000519426.1
ENST00000265433.3
NBN
nibrin
chr1_+_186344883 14.67 ENST00000367470.3
C1orf27
chromosome 1 open reading frame 27
chr1_+_186344945 14.58 ENST00000419367.3
ENST00000287859.6
C1orf27
chromosome 1 open reading frame 27
chr17_-_5342380 14.53 ENST00000225698.4
C1QBP
complement component 1, q subcomponent binding protein
chr12_+_48357401 14.50 ENST00000429772.2
ENST00000449758.2
TMEM106C
transmembrane protein 106C
chr6_+_13615554 14.36 ENST00000451315.2
NOL7
nucleolar protein 7, 27kDa
chr12_-_48099754 14.35 ENST00000380650.4
RPAP3
RNA polymerase II associated protein 3
chr7_-_102119342 14.28 ENST00000393794.3
ENST00000292614.5
POLR2J
polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr21_-_26979786 13.62 ENST00000419219.1
ENST00000352957.4
ENST00000307301.7
MRPL39
mitochondrial ribosomal protein L39
chr5_+_167913450 13.09 ENST00000231572.3
ENST00000538719.1
RARS
arginyl-tRNA synthetase
chr14_-_50319758 12.74 ENST00000298310.5
NEMF
nuclear export mediator factor
chr4_-_140216948 12.67 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr12_+_123237321 12.62 ENST00000280557.6
ENST00000455982.2
DENR
density-regulated protein
chr6_+_138725343 12.61 ENST00000607197.1
ENST00000367697.3
HEBP2
heme binding protein 2
chr14_-_54908043 12.44 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr1_+_212208919 12.41 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr12_-_48099773 12.31 ENST00000432584.3
ENST00000005386.3
RPAP3
RNA polymerase II associated protein 3
chr2_+_171785824 12.22 ENST00000452526.2
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr12_+_104609550 12.14 ENST00000525566.1
ENST00000429002.2
TXNRD1
thioredoxin reductase 1
chr14_-_50319482 11.88 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
NEMF
nuclear export mediator factor
chr9_+_71650645 11.42 ENST00000396366.2
FXN
frataxin
chr16_+_22308717 11.36 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr1_+_29063119 11.19 ENST00000474884.1
ENST00000542507.1
YTHDF2
YTH domain family, member 2
chr8_-_90996459 10.90 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr16_+_4674814 10.87 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr19_-_19051927 10.52 ENST00000600077.1
HOMER3
homer homolog 3 (Drosophila)
chr8_-_102217515 10.38 ENST00000520347.1
ENST00000523922.1
ENST00000520984.1
ZNF706
zinc finger protein 706
chr19_+_5690297 10.34 ENST00000582463.1
ENST00000579446.1
ENST00000394580.2
RPL36
ribosomal protein L36
chr15_-_66790146 10.29 ENST00000316634.5
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr6_+_155054459 10.29 ENST00000367178.3
ENST00000417268.1
ENST00000367186.4
SCAF8
SR-related CTD-associated factor 8
chr7_-_5569588 10.22 ENST00000417101.1
ACTB
actin, beta
chr1_+_95699704 10.21 ENST00000370202.4
RWDD3
RWD domain containing 3
chr9_-_139371533 10.16 ENST00000290037.6
ENST00000431893.2
ENST00000371706.3
SEC16A
SEC16 homolog A (S. cerevisiae)
chr2_+_171785012 10.11 ENST00000234160.4
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr19_+_10982336 10.03 ENST00000344150.4
CARM1
coactivator-associated arginine methyltransferase 1
chr20_+_44441271 10.03 ENST00000335046.3
ENST00000243893.6
UBE2C
ubiquitin-conjugating enzyme E2C
chr13_+_76123883 9.92 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr20_+_44441626 9.90 ENST00000372568.4
UBE2C
ubiquitin-conjugating enzyme E2C
chr16_-_47177874 9.75 ENST00000562435.1
NETO2
neuropilin (NRP) and tolloid (TLL)-like 2
chr4_-_120988229 9.67 ENST00000296509.6
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr8_-_102217796 9.62 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
ZNF706
zinc finger protein 706
chr7_-_96339132 9.62 ENST00000413065.1
SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr7_-_16840820 9.60 ENST00000450569.1
AGR2
anterior gradient 2
chr12_+_7033616 9.59 ENST00000356654.4
ATN1
atrophin 1
chr19_+_17416457 9.52 ENST00000252602.1
MRPL34
mitochondrial ribosomal protein L34
chr19_+_5690207 9.47 ENST00000347512.3
RPL36
ribosomal protein L36
chr20_+_48807351 9.38 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr19_+_17416609 9.37 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr1_-_37980344 9.31 ENST00000448519.2
ENST00000373075.2
ENST00000373073.4
ENST00000296214.5
MEAF6
MYST/Esa1-associated factor 6
chr16_+_4674787 9.29 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr1_+_193091080 9.23 ENST00000367435.3
CDC73
cell division cycle 73
chr3_+_184080790 9.15 ENST00000430783.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr17_-_76183111 9.10 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
TK1
thymidine kinase 1, soluble
chr11_+_46368975 9.10 ENST00000527911.1
DGKZ
diacylglycerol kinase, zeta
chr11_+_8008867 8.92 ENST00000309828.4
ENST00000449102.2
EIF3F
eukaryotic translation initiation factor 3, subunit F
chr11_-_66206260 8.89 ENST00000329819.4
ENST00000310999.7
ENST00000430466.2
MRPL11
mitochondrial ribosomal protein L11
chr19_-_2050852 8.88 ENST00000541165.1
ENST00000591601.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr1_+_10490779 8.79 ENST00000477755.1
APITD1
apoptosis-inducing, TAF9-like domain 1
chr2_-_96874553 8.79 ENST00000337288.5
ENST00000443962.1
STARD7
StAR-related lipid transfer (START) domain containing 7
chr10_+_81107271 8.77 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr10_+_13628921 8.71 ENST00000378572.3
PRPF18
pre-mRNA processing factor 18
chr1_+_29063439 8.65 ENST00000541996.1
ENST00000496288.1
YTHDF2
YTH domain family, member 2
chr20_-_1447467 8.59 ENST00000353088.2
ENST00000350991.4
NSFL1C
NSFL1 (p97) cofactor (p47)
chr5_-_179050066 8.48 ENST00000329433.6
ENST00000510411.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr20_+_60878005 8.42 ENST00000253003.2
ADRM1
adhesion regulating molecule 1
chr17_+_38137073 8.37 ENST00000541736.1
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr2_+_231921574 8.36 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr1_-_6614565 8.33 ENST00000377705.5
NOL9
nucleolar protein 9
chr19_-_19051993 8.27 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3
homer homolog 3 (Drosophila)
chr20_+_44441304 8.24 ENST00000352551.5
UBE2C
ubiquitin-conjugating enzyme E2C
chr1_+_29063271 8.21 ENST00000373812.3
YTHDF2
YTH domain family, member 2
chr17_-_79827808 8.17 ENST00000580685.1
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr2_+_131100710 8.17 ENST00000452955.1
IMP4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr19_-_48894762 8.11 ENST00000600980.1
ENST00000330720.2
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr6_+_32821924 8.10 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr17_-_79995553 8.06 ENST00000581584.1
ENST00000577712.1
ENST00000582900.1
ENST00000579155.1
ENST00000306869.2
DCXR
dicarbonyl/L-xylulose reductase
chr11_+_20409070 8.05 ENST00000331079.6
PRMT3
protein arginine methyltransferase 3
chr20_+_44441215 7.98 ENST00000356455.4
ENST00000405520.1
UBE2C
ubiquitin-conjugating enzyme E2C
chr20_-_1447547 7.95 ENST00000476071.1
NSFL1C
NSFL1 (p97) cofactor (p47)
chr11_+_46368956 7.93 ENST00000543978.1
DGKZ
diacylglycerol kinase, zeta
chr21_-_44527613 7.90 ENST00000380276.2
ENST00000398137.1
ENST00000291552.4
U2AF1
U2 small nuclear RNA auxiliary factor 1
chr3_-_64009658 7.74 ENST00000394431.2
PSMD6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr15_-_66679019 7.72 ENST00000568216.1
ENST00000562124.1
ENST00000570251.1
TIPIN
TIMELESS interacting protein
chr3_-_128369643 7.67 ENST00000296255.3
RPN1
ribophorin I
chr16_+_69345243 7.65 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr15_+_63340734 7.64 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr3_+_141457030 7.63 ENST00000273480.3
RNF7
ring finger protein 7
chr10_-_96122682 7.62 ENST00000371361.3
NOC3L
nucleolar complex associated 3 homolog (S. cerevisiae)
chr19_-_55652290 7.58 ENST00000589745.1
TNNT1
troponin T type 1 (skeletal, slow)
chr3_+_184081175 7.57 ENST00000452961.1
ENST00000296223.3
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr3_+_184081213 7.57 ENST00000429568.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr17_+_49230897 7.55 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME1
NME1-NME2
NME2
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr12_+_12966250 7.54 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DDX47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr11_+_46369077 7.50 ENST00000456247.2
ENST00000421244.2
ENST00000318201.8
DGKZ
diacylglycerol kinase, zeta
chr6_+_119215308 7.50 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr11_-_66103867 7.47 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr3_+_58291965 7.41 ENST00000445193.3
ENST00000295959.5
ENST00000466547.1
RPP14
ribonuclease P/MRP 14kDa subunit
chr3_-_48723268 7.37 ENST00000439518.1
ENST00000416649.2
ENST00000341520.4
ENST00000294129.2
NCKIPSD
NCK interacting protein with SH3 domain
chr11_+_67374323 7.33 ENST00000322776.6
ENST00000532303.1
ENST00000532244.1
ENST00000528328.1
ENST00000529927.1
ENST00000532343.1
ENST00000415352.2
ENST00000533075.1
ENST00000529867.1
ENST00000530638.1
NDUFV1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr1_+_32687971 7.32 ENST00000373586.1
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr2_+_190526111 7.32 ENST00000607062.1
ENST00000260952.4
ENST00000425590.1
ENST00000607535.1
ENST00000420250.1
ENST00000606910.1
ENST00000607690.1
ENST00000607829.1
ASNSD1
asparagine synthetase domain containing 1
chr5_-_179233934 7.31 ENST00000292591.7
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr17_+_28804380 7.24 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
GOSR1
golgi SNAP receptor complex member 1
chr8_+_145149930 7.23 ENST00000318911.4
CYC1
cytochrome c-1
chr1_-_156675535 7.22 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr7_+_141438393 7.16 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
SSBP1
single-stranded DNA binding protein 1, mitochondrial
chr16_-_88851618 7.12 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr1_-_1284730 6.97 ENST00000378888.5
DVL1
dishevelled segment polarity protein 1
chr19_+_23945768 6.96 ENST00000486528.1
ENST00000496398.1
RPSAP58
ribosomal protein SA pseudogene 58
chr7_-_27219849 6.90 ENST00000396344.4
HOXA10
homeobox A10
chr17_-_36891830 6.90 ENST00000578487.1
PCGF2
polycomb group ring finger 2
chr2_+_177134134 6.86 ENST00000249442.6
ENST00000392529.2
ENST00000443241.1
MTX2
metaxin 2
chr4_+_99916765 6.82 ENST00000296411.6
METAP1
methionyl aminopeptidase 1
chr3_+_184081137 6.81 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr13_-_37573432 6.79 ENST00000413537.2
ENST00000443765.1
ENST00000239891.3
ALG5
ALG5, dolichyl-phosphate beta-glucosyltransferase
chr4_-_183838596 6.75 ENST00000508994.1
ENST00000512766.1
DCTD
dCMP deaminase
chr19_+_10982189 6.64 ENST00000327064.4
ENST00000588947.1
CARM1
coactivator-associated arginine methyltransferase 1
chrX_+_47053208 6.58 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
UBA1
ubiquitin-like modifier activating enzyme 1
chr12_-_56583243 6.57 ENST00000550164.1
SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr5_+_137688285 6.57 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chr11_-_64013663 6.51 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_-_36615051 6.49 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr3_-_48647470 6.48 ENST00000203407.5
UQCRC1
ubiquinol-cytochrome c reductase core protein I
chr3_-_64009102 6.46 ENST00000478185.1
ENST00000482510.1
ENST00000497323.1
ENST00000492933.1
ENST00000295901.4
PSMD6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr12_-_51663959 6.45 ENST00000604188.1
ENST00000398453.3
SMAGP
small cell adhesion glycoprotein
chr12_-_120638902 6.45 ENST00000551150.1
ENST00000313104.5
ENST00000547191.1
ENST00000546989.1
ENST00000392514.4
ENST00000228306.4
ENST00000550856.1
RPLP0
ribosomal protein, large, P0
chr12_-_51664058 6.41 ENST00000605627.1
SMAGP
small cell adhesion glycoprotein
chr19_-_14682838 6.41 ENST00000215565.2
NDUFB7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
chr17_-_3749515 6.39 ENST00000158149.3
ENST00000389005.4
C17orf85
chromosome 17 open reading frame 85
chr12_-_120907374 6.34 ENST00000550458.1
SRSF9
serine/arginine-rich splicing factor 9
chr4_-_183838372 6.28 ENST00000503820.1
ENST00000503988.1
DCTD
dCMP deaminase
chr3_-_183602515 6.25 ENST00000449306.1
ENST00000435888.1
ENST00000311101.5
ENST00000317096.4
PARL
presenilin associated, rhomboid-like
chr19_-_10530784 6.18 ENST00000593124.1
CDC37
cell division cycle 37
chr2_+_90108504 6.18 ENST00000390271.2
IGKV6D-41
immunoglobulin kappa variable 6D-41 (non-functional)
chr22_-_22901477 6.16 ENST00000420709.1
ENST00000398741.1
ENST00000405655.3
PRAME
preferentially expressed antigen in melanoma
chrX_+_123094369 6.11 ENST00000455404.1
ENST00000218089.9
STAG2
stromal antigen 2
chr2_-_151344172 6.07 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr17_+_38137050 6.00 ENST00000264639.4
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr15_-_55489097 6.00 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr12_-_102224704 5.98 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr8_-_71520513 5.97 ENST00000262213.2
ENST00000536748.1
ENST00000518678.1
TRAM1
translocation associated membrane protein 1
chr17_-_1090599 5.94 ENST00000544583.2
ABR
active BCR-related
chr12_-_46384334 5.94 ENST00000369367.3
ENST00000266589.6
ENST00000395453.2
ENST00000395454.2
SCAF11
SR-related CTD-associated factor 11
chr9_+_131451480 5.93 ENST00000322030.8
SET
SET nuclear oncogene
chr1_+_110527308 5.93 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr16_+_53088885 5.90 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chrX_-_153285395 5.85 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chr2_+_118572226 5.83 ENST00000263239.2
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr16_-_30441293 5.79 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
DCTPP1
dCTP pyrophosphatase 1
chr16_-_11891048 5.73 ENST00000571198.1
ENST00000572781.1
ENST00000355758.4
ZC3H7A
zinc finger CCCH-type containing 7A
chr7_-_96339167 5.69 ENST00000444799.1
ENST00000417009.1
ENST00000248566.2
SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr4_-_183838747 5.67 ENST00000438320.2
DCTD
dCMP deaminase
chr2_-_130939115 5.66 ENST00000441135.1
ENST00000339679.7
ENST00000426662.2
ENST00000443958.2
ENST00000351288.6
ENST00000453750.1
ENST00000452225.2
SMPD4
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chrX_-_153285251 5.64 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr12_-_54070098 5.64 ENST00000394349.3
ENST00000549164.1
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr8_+_22436248 5.63 ENST00000308354.7
PDLIM2
PDZ and LIM domain 2 (mystique)
chr15_+_63340647 5.58 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chr3_+_141457105 5.58 ENST00000480908.1
ENST00000393000.3
RNF7
ring finger protein 7
chr12_-_54069856 5.57 ENST00000602871.1
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr1_-_75198940 5.52 ENST00000417775.1
CRYZ
crystallin, zeta (quinone reductase)
chr7_+_89783689 5.52 ENST00000297205.2
STEAP1
six transmembrane epithelial antigen of the prostate 1
chr6_-_99797522 5.46 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr22_-_22901636 5.42 ENST00000406503.1
ENST00000439106.1
ENST00000402697.1
ENST00000543184.1
ENST00000398743.2
PRAME
preferentially expressed antigen in melanoma
chr10_+_13203543 5.40 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
MCM10
minichromosome maintenance complex component 10
chr15_+_66679155 5.36 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr17_+_79670386 5.34 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
MRPL12
SLC25A10
SLC25A10
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr11_+_66025938 5.31 ENST00000394066.2
KLC2
kinesin light chain 2
chr13_-_48669232 5.30 ENST00000258648.2
ENST00000378586.1
MED4
mediator complex subunit 4
chr4_-_100815525 5.26 ENST00000226522.8
ENST00000499666.2
LAMTOR3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr7_-_102213030 5.26 ENST00000511313.1
ENST00000513438.1
ENST00000513506.1
POLR2J3
polymerase (RNA) II (DNA directed) polypeptide J3
chr11_+_60691924 5.25 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A
transmembrane protein 132A
chr12_-_51663728 5.25 ENST00000603864.1
ENST00000605426.1
SMAGP
small cell adhesion glycoprotein
chr2_+_177134201 5.22 ENST00000452865.1
MTX2
metaxin 2
chr11_+_64781575 5.21 ENST00000246747.4
ENST00000529384.1
ARL2
ADP-ribosylation factor-like 2
chr21_-_33975547 5.21 ENST00000431599.1
C21orf59
chromosome 21 open reading frame 59
chr17_+_65713925 5.19 ENST00000253247.4
NOL11
nucleolar protein 11
chr4_-_183838482 5.17 ENST00000357067.3
ENST00000510370.1
DCTD
dCMP deaminase
chr2_+_90060377 5.17 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)

Network of associatons between targets according to the STRING database.

First level regulatory network of CTCF_CTCFL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
12.4 37.1 GO:0071344 diphosphate metabolic process(GO:0071344)
10.7 32.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
8.6 34.5 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
5.9 23.8 GO:0031860 telomeric 3' overhang formation(GO:0031860)
5.2 20.6 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
5.0 39.9 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
4.8 33.6 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
4.4 13.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
4.2 12.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
4.2 12.6 GO:0002188 translation reinitiation(GO:0002188)
3.8 11.4 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
3.8 18.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
3.6 14.5 GO:1901165 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of trophoblast cell migration(GO:1901165)
3.4 23.9 GO:0006226 dUMP biosynthetic process(GO:0006226)
3.3 16.7 GO:0034971 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R17 methylation(GO:0034971)
2.9 5.8 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
2.7 21.8 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
2.5 7.6 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
2.5 4.9 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
2.4 7.1 GO:0032203 telomere formation via telomerase(GO:0032203)
2.3 9.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
2.3 7.0 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
2.3 34.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.3 9.1 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
2.3 2.3 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)
2.2 22.0 GO:0051096 positive regulation of helicase activity(GO:0051096)
2.1 8.4 GO:0043248 proteasome assembly(GO:0043248)
2.1 6.2 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
2.0 20.0 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
2.0 5.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
1.9 5.7 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
1.9 7.5 GO:0005997 xylulose metabolic process(GO:0005997)
1.8 7.3 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
1.8 10.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.8 12.6 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
1.8 5.4 GO:1903028 positive regulation of opsonization(GO:1903028)
1.8 7.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.8 5.3 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
1.7 15.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
1.7 20.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
1.6 4.8 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.5 7.7 GO:0048478 replication fork protection(GO:0048478)
1.5 6.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.5 4.4 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.5 7.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
1.5 7.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
1.5 8.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
1.4 8.7 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
1.4 5.5 GO:1903412 response to bile acid(GO:1903412)
1.4 4.1 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
1.3 12.1 GO:0001887 selenium compound metabolic process(GO:0001887)
1.3 12.0 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
1.3 5.3 GO:1904753 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
1.2 2.5 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
1.2 9.9 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.2 4.8 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
1.2 13.2 GO:0045116 protein neddylation(GO:0045116)
1.2 7.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.2 3.5 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
1.2 3.5 GO:0006097 glyoxylate cycle(GO:0006097)
1.1 21.8 GO:0070200 establishment of protein localization to telomere(GO:0070200)
1.1 7.9 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
1.1 3.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
1.1 3.3 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
1.1 8.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
1.0 3.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
1.0 7.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
1.0 3.0 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
1.0 8.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
1.0 24.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
1.0 13.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.0 10.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
1.0 46.7 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.9 9.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.9 6.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.9 4.5 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.9 5.4 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.9 4.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.9 3.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.9 3.5 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.9 62.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.8 9.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.8 2.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.8 11.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.8 4.9 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.8 4.9 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.8 2.4 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.8 3.2 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.8 2.3 GO:0075528 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.8 7.6 GO:0045444 fat cell differentiation(GO:0045444)
0.8 7.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.8 8.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.8 2.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.7 7.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.7 13.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.7 8.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.7 6.6 GO:0072718 response to cisplatin(GO:0072718)
0.7 7.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.7 2.8 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.7 8.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.7 6.9 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.7 17.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.7 2.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.7 2.0 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.6 10.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.6 5.2 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.6 4.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.6 3.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.6 15.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.6 10.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.6 4.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.6 11.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.6 5.9 GO:2000210 positive regulation of anoikis(GO:2000210)
0.6 2.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.6 16.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.6 5.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.6 2.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.6 12.2 GO:0035855 megakaryocyte development(GO:0035855)
0.6 1.7 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.6 1.1 GO:0030242 pexophagy(GO:0030242)
0.5 4.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.5 3.8 GO:0048318 axial mesoderm development(GO:0048318)
0.5 4.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.5 1.6 GO:0090427 activation of meiosis(GO:0090427)
0.5 2.7 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.5 2.1 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.5 51.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.5 8.8 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.5 2.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.5 12.6 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.5 9.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.5 2.0 GO:0060708 histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) spongiotrophoblast differentiation(GO:0060708) regulation of histone H3-K27 acetylation(GO:1901674)
0.5 16.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.5 1.9 GO:0061484 inner cell mass cell differentiation(GO:0001826) hematopoietic stem cell homeostasis(GO:0061484)
0.5 3.7 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.5 4.1 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125)
0.5 4.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.4 29.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 1.7 GO:0060268 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.4 1.7 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 2.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.4 12.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.4 5.0 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.4 23.5 GO:0021762 substantia nigra development(GO:0021762)
0.4 1.6 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.4 1.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.4 3.4 GO:0042407 cristae formation(GO:0042407)
0.4 15.6 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.4 4.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 1.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.4 2.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.3 27.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.3 2.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.3 1.6 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.3 14.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 1.3 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 4.1 GO:0060056 mammary gland involution(GO:0060056)
0.3 0.9 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.3 6.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.3 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.3 5.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.3 1.7 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.3 2.0 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3 1.1 GO:0035973 aggrephagy(GO:0035973)
0.3 9.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.3 7.8 GO:0051290 protein heterotetramerization(GO:0051290)
0.3 1.0 GO:0015808 L-alanine transport(GO:0015808)
0.3 1.0 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.3 3.3 GO:0035058 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855) positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3 3.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 6.5 GO:0071174 mitotic spindle checkpoint(GO:0071174)
0.2 14.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 4.5 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.2 30.0 GO:0007030 Golgi organization(GO:0007030)
0.2 7.0 GO:0051028 mRNA transport(GO:0051028)
0.2 22.8 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.2 10.1 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.2 2.6 GO:0070986 left/right axis specification(GO:0070986)
0.2 4.7 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.2 11.1 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.2 3.4 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.2 6.6 GO:0006491 N-glycan processing(GO:0006491)
0.2 4.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 6.6 GO:0060065 uterus development(GO:0060065)
0.2 7.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.2 2.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2 11.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 19.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.2 0.6 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 1.1 GO:0042426 choline catabolic process(GO:0042426)
0.2 3.1 GO:0007172 signal complex assembly(GO:0007172)
0.2 2.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 0.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 1.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 6.8 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 0.9 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.2 2.9 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 5.2 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.2 6.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 6.0 GO:0006270 DNA replication initiation(GO:0006270)
0.2 2.2 GO:0031648 protein destabilization(GO:0031648)
0.2 0.8 GO:2000812 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.2 0.9 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 2.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 2.5 GO:0016540 protein autoprocessing(GO:0016540)
0.1 2.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 6.1 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.1 3.7 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 1.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.6 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 5.7 GO:0006739 NADP metabolic process(GO:0006739)
0.1 1.4 GO:0019985 translesion synthesis(GO:0019985)
0.1 1.0 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 1.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 1.3 GO:0015886 heme transport(GO:0015886)
0.1 0.5 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.6 GO:0006295 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.7 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 2.6 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.7 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 1.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 3.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 3.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044) positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.4 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 34.6 GO:0008380 RNA splicing(GO:0008380)
0.1 8.8 GO:0006413 translational initiation(GO:0006413)
0.1 1.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 4.4 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.1 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.1 GO:0006907 pinocytosis(GO:0006907)
0.1 3.1 GO:0006754 ATP biosynthetic process(GO:0006754)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 2.0 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 3.1 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.1 3.8 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 1.1 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 2.9 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 1.1 GO:0051764 actin crosslink formation(GO:0051764)
0.1 2.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.9 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 1.8 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 1.1 GO:0006511 ubiquitin-dependent protein catabolic process(GO:0006511)
0.1 3.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 8.0 GO:0002377 immunoglobulin production(GO:0002377)
0.1 5.1 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 5.7 GO:0006364 rRNA processing(GO:0006364)
0.1 1.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 3.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.9 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.7 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 4.8 GO:0070268 cornification(GO:0070268)
0.0 0.8 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 1.3 GO:0035329 hippo signaling(GO:0035329)
0.0 6.0 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.8 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 3.0 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.9 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.0 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.8 GO:0045624 positive regulation of T-helper cell differentiation(GO:0045624)
0.0 1.3 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.3 GO:0044839 cell cycle G2/M phase transition(GO:0044839)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.7 GO:0006284 base-excision repair(GO:0006284)
0.0 0.9 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 0.3 GO:0032801 receptor catabolic process(GO:0032801)
0.0 3.2 GO:0051168 nuclear export(GO:0051168)
0.0 0.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.8 GO:0006897 endocytosis(GO:0006897)
0.0 1.5 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.9 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.4 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.0 GO:0032252 secretory granule localization(GO:0032252)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 79.9 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
6.8 34.2 GO:0097149 centralspindlin complex(GO:0097149)
6.2 24.8 GO:0070876 SOSS complex(GO:0070876)
6.1 61.2 GO:0097255 R2TP complex(GO:0097255)
4.4 13.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
4.1 16.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
3.7 25.6 GO:0030870 Mre11 complex(GO:0030870)
2.9 23.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
2.6 7.9 GO:0034455 t-UTP complex(GO:0034455)
2.3 11.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
2.3 22.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
1.9 5.7 GO:0071020 post-spliceosomal complex(GO:0071020)
1.8 7.2 GO:0005797 Golgi medial cisterna(GO:0005797)
1.8 16.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.8 16.1 GO:0031298 replication fork protection complex(GO:0031298)
1.8 12.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.8 5.3 GO:0016938 kinesin I complex(GO:0016938)
1.8 14.0 GO:1990111 spermatoproteasome complex(GO:1990111)
1.7 51.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
1.6 8.2 GO:0034457 Mpp10 complex(GO:0034457)
1.6 4.9 GO:0031523 Myb complex(GO:0031523)
1.6 63.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.6 7.9 GO:0089701 U2AF(GO:0089701)
1.6 4.7 GO:0070939 Dsl1p complex(GO:0070939)
1.4 44.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
1.4 25.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.3 3.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.2 13.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
1.2 9.7 GO:0031931 TORC1 complex(GO:0031931)
1.2 36.2 GO:0005680 anaphase-promoting complex(GO:0005680)
1.2 10.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.1 4.4 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
1.1 5.3 GO:0071986 Ragulator complex(GO:0071986)
1.0 22.6 GO:0005838 proteasome regulatory particle(GO:0005838)
1.0 7.2 GO:1990635 proximal dendrite(GO:1990635)
1.0 10.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.0 9.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.0 11.6 GO:0030008 TRAPP complex(GO:0030008)
0.9 9.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.9 5.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.9 3.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.8 11.7 GO:0031209 SCAR complex(GO:0031209)
0.8 8.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.8 10.1 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.8 39.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.7 10.3 GO:0035102 PRC1 complex(GO:0035102)
0.7 5.1 GO:0032584 growth cone membrane(GO:0032584)
0.7 9.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.6 9.7 GO:0090543 Flemming body(GO:0090543)
0.6 1.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.6 1.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.6 7.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.6 15.3 GO:0005861 troponin complex(GO:0005861)
0.6 13.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.6 2.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.6 2.9 GO:0070847 core mediator complex(GO:0070847)
0.6 3.5 GO:0090661 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.6 7.0 GO:1990909 Wnt signalosome(GO:1990909)
0.6 8.1 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.5 1.6 GO:0030689 Noc complex(GO:0030689)
0.5 1.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.5 55.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.5 17.8 GO:0090544 BAF-type complex(GO:0090544)
0.5 4.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.5 3.4 GO:0061617 MICOS complex(GO:0061617)
0.5 3.7 GO:0032433 filopodium tip(GO:0032433)
0.5 4.1 GO:0071439 clathrin complex(GO:0071439)
0.4 29.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4 5.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 2.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.4 6.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4 1.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.4 2.5 GO:0016589 NURF complex(GO:0016589)
0.3 2.7 GO:0051286 cell tip(GO:0051286)
0.3 4.9 GO:0005869 dynactin complex(GO:0005869)
0.3 1.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 4.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.3 25.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 3.9 GO:0097433 dense body(GO:0097433)
0.3 0.6 GO:0031213 RSF complex(GO:0031213)
0.3 13.2 GO:0008180 COP9 signalosome(GO:0008180)
0.3 7.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.3 1.0 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.3 8.8 GO:0032420 stereocilium(GO:0032420)
0.2 1.2 GO:0001940 male pronucleus(GO:0001940)
0.2 34.1 GO:0005840 ribosome(GO:0005840)
0.2 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 16.5 GO:0045178 basal part of cell(GO:0045178)
0.2 1.5 GO:0070522 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.2 2.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 1.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 2.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 1.1 GO:1990130 EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 20.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 10.0 GO:0015030 Cajal body(GO:0015030)
0.2 3.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 3.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 9.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 20.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 12.0 GO:0016605 PML body(GO:0016605)
0.1 1.8 GO:0044754 autolysosome(GO:0044754)
0.1 2.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 51.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 14.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 2.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 19.0 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.9 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 2.4 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.1 12.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 0.9 GO:0044194 cytolytic granule(GO:0044194)
0.1 3.1 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 3.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 3.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 14.9 GO:0001650 fibrillar center(GO:0001650)
0.1 4.8 GO:0031519 PcG protein complex(GO:0031519)
0.1 16.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 5.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 4.0 GO:0045095 keratin filament(GO:0045095)
0.1 6.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 0.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 4.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 1.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 4.6 GO:0016324 apical plasma membrane(GO:0016324)
0.1 1.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.4 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 6.4 GO:0005643 nuclear pore(GO:0005643)
0.1 3.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 26.4 GO:0000785 chromatin(GO:0000785)
0.1 2.4 GO:0097546 ciliary base(GO:0097546)
0.1 7.6 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 4.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 10.4 GO:0030027 lamellipodium(GO:0030027)
0.0 5.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 12.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 2.1 GO:0005811 lipid particle(GO:0005811)
0.0 4.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.0 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 19.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.6 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 32.6 GO:0004427 inorganic diphosphatase activity(GO:0004427)
6.0 23.9 GO:0004132 dCMP deaminase activity(GO:0004132)
5.7 34.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
4.8 14.5 GO:0030984 kininogen binding(GO:0030984)
4.4 13.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
4.0 12.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
3.0 9.1 GO:0004797 thymidine kinase activity(GO:0004797)
2.7 8.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
2.5 51.9 GO:0001055 RNA polymerase II activity(GO:0001055)
2.5 24.7 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
2.4 7.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
2.3 23.5 GO:1990446 U1 snRNP binding(GO:1990446)
2.3 28.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
2.3 32.1 GO:0016018 cyclosporin A binding(GO:0016018)
2.3 24.8 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
2.2 13.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
2.0 8.1 GO:0005046 KDEL sequence binding(GO:0005046)
1.9 25.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
1.9 5.7 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
1.8 5.3 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
1.7 6.9 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.7 8.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
1.6 11.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
1.6 7.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.6 4.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.5 26.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
1.5 7.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
1.3 14.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
1.3 11.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.2 4.9 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.2 8.4 GO:0061133 endopeptidase activator activity(GO:0061133)
1.2 7.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.2 3.5 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
1.1 5.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
1.1 7.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.1 3.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
1.1 15.3 GO:0031014 troponin T binding(GO:0031014)
1.1 4.3 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
1.0 3.1 GO:0070025 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
1.0 7.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.0 3.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.0 9.9 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.0 9.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.0 20.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
1.0 6.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.9 6.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.9 42.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.9 4.6 GO:0048256 flap endonuclease activity(GO:0048256)
0.9 13.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.8 26.9 GO:0070064 proline-rich region binding(GO:0070064)
0.8 2.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.8 5.8 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.8 8.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.8 2.4 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.8 2.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.8 4.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.8 2.3 GO:0070404 NADH binding(GO:0070404)
0.7 28.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.7 7.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.7 10.2 GO:0030957 Tat protein binding(GO:0030957)
0.7 13.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.7 1.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.7 6.2 GO:0035877 death effector domain binding(GO:0035877)
0.7 7.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.7 2.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.7 42.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.6 10.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.6 1.8 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.6 3.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.6 37.3 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.6 2.8 GO:0004905 type I interferon receptor activity(GO:0004905)
0.6 5.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.6 4.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 5.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.5 113.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.5 3.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.5 3.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.5 20.5 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.5 12.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.5 3.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.5 2.9 GO:0046979 TAP2 binding(GO:0046979)
0.5 10.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.5 5.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.5 9.5 GO:0051400 BH domain binding(GO:0051400)
0.5 7.2 GO:0019841 retinol binding(GO:0019841)
0.4 4.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.4 3.1 GO:0017166 vinculin binding(GO:0017166)
0.4 4.7 GO:0004645 phosphorylase activity(GO:0004645)
0.4 3.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.4 11.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 4.4 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 9.6 GO:0002162 dystroglycan binding(GO:0002162)
0.4 11.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.4 5.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.4 8.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.4 7.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.4 11.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 8.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 13.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 11.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 18.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 4.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.3 31.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 2.9 GO:0031386 protein tag(GO:0031386)
0.3 0.9 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.3 3.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 4.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 1.0 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.3 4.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 2.5 GO:0042731 PH domain binding(GO:0042731)
0.2 4.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 1.0 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 3.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 4.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 9.9 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 3.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 2.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 0.9 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 7.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 2.0 GO:0005000 vasopressin receptor activity(GO:0005000)
0.2 1.6 GO:0004977 melanocortin receptor activity(GO:0004977)
0.2 1.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 2.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 1.5 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 6.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 24.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 2.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 9.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.2 0.8 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.2 8.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 4.4 GO:0005123 death receptor binding(GO:0005123)
0.2 0.6 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 5.0 GO:0031489 myosin V binding(GO:0031489)
0.2 2.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 0.9 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 0.7 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.2 2.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 0.9 GO:0004771 sterol esterase activity(GO:0004771)
0.2 5.0 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.2 0.9 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 6.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 14.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.2 2.3 GO:0043495 protein anchor(GO:0043495)
0.2 1.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 4.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 2.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 1.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 4.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.3 GO:0015232 heme transporter activity(GO:0015232)
0.1 5.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 2.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 2.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 4.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 3.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 10.1 GO:0005518 collagen binding(GO:0005518)
0.1 1.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 2.4 GO:0071949 FAD binding(GO:0071949)
0.1 1.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 5.4 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 5.9 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 3.2 GO:0043531 ADP binding(GO:0043531)
0.1 2.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.0 GO:0030275 LRR domain binding(GO:0030275)
0.1 33.4 GO:0045296 cadherin binding(GO:0045296)
0.1 0.4 GO:0032052 bile acid binding(GO:0032052)
0.1 0.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.8 GO:0050681 androgen receptor binding(GO:0050681)
0.1 2.0 GO:0043022 ribosome binding(GO:0043022)
0.1 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 1.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.9 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 9.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.1 GO:0002039 p53 binding(GO:0002039)
0.1 0.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 1.9 GO:0005262 calcium channel activity(GO:0005262) calcium ion transmembrane transporter activity(GO:0015085)
0.1 2.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 4.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.2 GO:0008233 peptidase activity(GO:0008233)
0.0 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 2.8 GO:0051087 chaperone binding(GO:0051087)
0.0 1.5 GO:0004386 helicase activity(GO:0004386)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 6.2 GO:0003924 GTPase activity(GO:0003924)
0.0 1.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 1.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 16.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.7 34.5 PID MYC PATHWAY C-MYC pathway
0.7 42.7 PID PLK1 PATHWAY PLK1 signaling events
0.6 37.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.4 7.7 PID ATR PATHWAY ATR signaling pathway
0.4 6.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.4 2.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.4 18.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.3 23.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 8.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 13.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.3 7.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 5.3 PID ARF 3PATHWAY Arf1 pathway
0.2 3.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2 6.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 7.8 PID IL3 PATHWAY IL3-mediated signaling events
0.2 6.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 4.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 11.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 4.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 15.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.2 7.8 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.2 18.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 4.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 3.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 9.0 PID P53 REGULATION PATHWAY p53 pathway
0.2 4.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.2 15.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 6.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.2 4.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 11.2 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 7.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 5.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 6.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 3.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.3 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 3.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 46.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
1.6 45.8 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.6 34.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
1.2 21.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
1.0 39.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.9 15.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.9 33.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.9 11.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.7 29.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.7 3.0 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.7 14.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.7 51.0 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.7 41.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.6 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.6 19.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5 40.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.5 36.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.5 43.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.5 11.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.5 65.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.5 9.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.5 8.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.5 18.9 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.4 2.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.4 5.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.4 1.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.4 6.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.4 3.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.4 13.1 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.4 9.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.4 2.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 5.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.4 7.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.4 4.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 20.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 9.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.3 24.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.3 7.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 7.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 10.2 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.3 7.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.3 8.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 2.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 7.5 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.2 5.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 0.2 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.2 9.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 1.9 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.2 4.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 7.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 4.4 REACTOME KINESINS Genes involved in Kinesins
0.2 4.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 8.5 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.1 3.6 REACTOME TRANSLATION Genes involved in Translation
0.1 2.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 10.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 3.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 6.0 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.1 3.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 4.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 14.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 2.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 3.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 9.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.5 REACTOME TRANSCRIPTION COUPLED NER TC NER Genes involved in Transcription-coupled NER (TC-NER)
0.1 1.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.5 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 1.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+