Project
averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for DLX1_HOXA3_BARX2
Z-value: 0.89
Motif logo
Transcription factors associated with DLX1_HOXA3_BARX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
DLX1
|
ENSG00000144355.10 | distal-less homeobox 1 |
|
HOXA3
|
ENSG00000105997.18 | homeobox A3 |
|
BARX2
|
ENSG00000043039.5 | BARX homeobox 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BARX2 | hg19_v2_chr11_+_129245796_129245835 | 0.23 | 6.5e-04 | Click! |
Activity profile of DLX1_HOXA3_BARX2 motif
Sorted Z-values of DLX1_HOXA3_BARX2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_117748138 | 18.05 |
ENST00000527717.1
|
FXYD6
|
FXYD domain containing ion transport regulator 6 |
| chrX_-_13835147 | 17.57 |
ENST00000493677.1
ENST00000355135.2 |
GPM6B
|
glycoprotein M6B |
| chr11_-_117747607 | 15.72 |
ENST00000540359.1
ENST00000539526.1 |
FXYD6
|
FXYD domain containing ion transport regulator 6 |
| chr11_-_117747434 | 15.35 |
ENST00000529335.2
ENST00000530956.1 ENST00000260282.4 |
FXYD6
|
FXYD domain containing ion transport regulator 6 |
| chr19_+_50016610 | 12.67 |
ENST00000596975.1
|
FCGRT
|
Fc fragment of IgG, receptor, transporter, alpha |
| chr3_+_111718036 | 11.96 |
ENST00000455401.2
|
TAGLN3
|
transgelin 3 |
| chr3_+_111718173 | 11.91 |
ENST00000494932.1
|
TAGLN3
|
transgelin 3 |
| chr3_+_111717600 | 10.64 |
ENST00000273368.4
|
TAGLN3
|
transgelin 3 |
| chr19_+_50016411 | 10.43 |
ENST00000426395.3
ENST00000600273.1 ENST00000599988.1 |
FCGRT
|
Fc fragment of IgG, receptor, transporter, alpha |
| chr3_+_111717511 | 10.36 |
ENST00000478951.1
ENST00000393917.2 |
TAGLN3
|
transgelin 3 |
| chr6_-_32908765 | 10.31 |
ENST00000416244.2
|
HLA-DMB
|
major histocompatibility complex, class II, DM beta |
| chr16_-_28634874 | 9.47 |
ENST00000395609.1
ENST00000350842.4 |
SULT1A1
|
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| chr11_+_121447469 | 9.03 |
ENST00000532694.1
ENST00000534286.1 |
SORL1
|
sortilin-related receptor, L(DLR class) A repeats containing |
| chr3_-_39321512 | 8.53 |
ENST00000399220.2
|
CX3CR1
|
chemokine (C-X3-C motif) receptor 1 |
| chr16_-_28937027 | 8.16 |
ENST00000358201.4
|
RABEP2
|
rabaptin, RAB GTPase binding effector protein 2 |
| chr11_-_128894053 | 7.81 |
ENST00000392657.3
|
ARHGAP32
|
Rho GTPase activating protein 32 |
| chr1_-_92952433 | 7.67 |
ENST00000294702.5
|
GFI1
|
growth factor independent 1 transcription repressor |
| chr6_+_160542870 | 6.87 |
ENST00000324965.4
ENST00000457470.2 |
SLC22A1
|
solute carrier family 22 (organic cation transporter), member 1 |
| chr6_-_32908792 | 6.84 |
ENST00000418107.2
|
HLA-DMB
|
major histocompatibility complex, class II, DM beta |
| chr4_-_87028478 | 6.82 |
ENST00000515400.1
ENST00000395157.3 |
MAPK10
|
mitogen-activated protein kinase 10 |
| chr12_-_15114603 | 6.71 |
ENST00000228945.4
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr2_-_224467093 | 6.51 |
ENST00000305409.2
|
SCG2
|
secretogranin II |
| chr19_+_45417921 | 6.24 |
ENST00000252491.4
ENST00000592885.1 ENST00000589781.1 |
APOC1
|
apolipoprotein C-I |
| chr18_+_32556892 | 6.16 |
ENST00000591734.1
ENST00000413393.1 ENST00000589180.1 ENST00000587359.1 |
MAPRE2
|
microtubule-associated protein, RP/EB family, member 2 |
| chr10_-_50970322 | 6.14 |
ENST00000374103.4
|
OGDHL
|
oxoglutarate dehydrogenase-like |
| chr2_+_90077680 | 6.09 |
ENST00000390270.2
|
IGKV3D-20
|
immunoglobulin kappa variable 3D-20 |
| chr17_-_73663245 | 5.50 |
ENST00000584999.1
ENST00000317905.5 ENST00000420326.2 ENST00000340830.5 |
RECQL5
|
RecQ protein-like 5 |
| chr14_+_61654271 | 5.50 |
ENST00000555185.1
ENST00000557294.1 ENST00000556778.1 |
PRKCH
|
protein kinase C, eta |
| chr10_-_50970382 | 5.47 |
ENST00000419399.1
ENST00000432695.1 |
OGDHL
|
oxoglutarate dehydrogenase-like |
| chr1_+_202317815 | 5.45 |
ENST00000608999.1
ENST00000336894.4 ENST00000480184.1 |
PPP1R12B
|
protein phosphatase 1, regulatory subunit 12B |
| chr21_-_15918618 | 5.32 |
ENST00000400564.1
ENST00000400566.1 |
SAMSN1
|
SAM domain, SH3 domain and nuclear localization signals 1 |
| chr12_-_10282836 | 5.30 |
ENST00000304084.8
ENST00000353231.5 ENST00000525605.1 |
CLEC7A
|
C-type lectin domain family 7, member A |
| chr6_+_160542821 | 5.28 |
ENST00000366963.4
|
SLC22A1
|
solute carrier family 22 (organic cation transporter), member 1 |
| chr7_+_80275953 | 5.27 |
ENST00000538969.1
ENST00000544133.1 ENST00000433696.2 |
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr4_-_8873531 | 5.08 |
ENST00000400677.3
|
HMX1
|
H6 family homeobox 1 |
| chr4_-_120243545 | 4.89 |
ENST00000274024.3
|
FABP2
|
fatty acid binding protein 2, intestinal |
| chr5_-_42811986 | 4.85 |
ENST00000511224.1
ENST00000507920.1 ENST00000510965.1 |
SEPP1
|
selenoprotein P, plasma, 1 |
| chr12_+_7014126 | 4.82 |
ENST00000415834.1
ENST00000436789.1 |
LRRC23
|
leucine rich repeat containing 23 |
| chr15_-_20193370 | 4.81 |
ENST00000558565.2
|
IGHV3OR15-7
|
immunoglobulin heavy variable 3/OR15-7 (pseudogene) |
| chr5_-_42812143 | 4.70 |
ENST00000514985.1
|
SEPP1
|
selenoprotein P, plasma, 1 |
| chr15_+_84115868 | 4.58 |
ENST00000427482.2
|
SH3GL3
|
SH3-domain GRB2-like 3 |
| chr11_-_129062093 | 4.38 |
ENST00000310343.9
|
ARHGAP32
|
Rho GTPase activating protein 32 |
| chr1_+_207226574 | 4.23 |
ENST00000367080.3
ENST00000367079.2 |
PFKFB2
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| chr4_-_176733897 | 4.20 |
ENST00000393658.2
|
GPM6A
|
glycoprotein M6A |
| chr11_-_111794446 | 4.19 |
ENST00000527950.1
|
CRYAB
|
crystallin, alpha B |
| chr12_+_81110684 | 4.15 |
ENST00000228644.3
|
MYF5
|
myogenic factor 5 |
| chr19_+_18942761 | 4.14 |
ENST00000599848.1
|
UPF1
|
UPF1 regulator of nonsense transcripts homolog (yeast) |
| chrX_+_1710484 | 4.12 |
ENST00000313871.3
ENST00000381261.3 |
AKAP17A
|
A kinase (PRKA) anchor protein 17A |
| chr4_-_46911223 | 4.05 |
ENST00000396533.1
|
COX7B2
|
cytochrome c oxidase subunit VIIb2 |
| chr12_+_8276495 | 4.05 |
ENST00000546339.1
|
CLEC4A
|
C-type lectin domain family 4, member A |
| chr11_-_64684672 | 4.00 |
ENST00000377264.3
ENST00000421419.2 |
ATG2A
|
autophagy related 2A |
| chr1_-_207226313 | 3.99 |
ENST00000367084.1
|
YOD1
|
YOD1 deubiquitinase |
| chr4_-_46911248 | 3.94 |
ENST00000355591.3
ENST00000505102.1 |
COX7B2
|
cytochrome c oxidase subunit VIIb2 |
| chr4_+_80584903 | 3.89 |
ENST00000506460.1
|
RP11-452C8.1
|
RP11-452C8.1 |
| chr12_-_719573 | 3.83 |
ENST00000397265.3
|
NINJ2
|
ninjurin 2 |
| chr12_-_10022735 | 3.79 |
ENST00000228438.2
|
CLEC2B
|
C-type lectin domain family 2, member B |
| chr7_-_37026108 | 3.77 |
ENST00000396045.3
|
ELMO1
|
engulfment and cell motility 1 |
| chr16_-_25122785 | 3.76 |
ENST00000563962.1
ENST00000569920.1 |
RP11-449H11.1
|
RP11-449H11.1 |
| chr17_-_73663168 | 3.73 |
ENST00000578201.1
ENST00000423245.2 |
RECQL5
|
RecQ protein-like 5 |
| chr1_+_198608146 | 3.73 |
ENST00000367376.2
ENST00000352140.3 ENST00000594404.1 ENST00000598951.1 ENST00000530727.1 ENST00000442510.2 ENST00000367367.4 ENST00000348564.6 ENST00000367364.1 ENST00000413409.2 |
PTPRC
|
protein tyrosine phosphatase, receptor type, C |
| chr2_+_90273679 | 3.62 |
ENST00000423080.2
|
IGKV3D-7
|
immunoglobulin kappa variable 3D-7 |
| chr12_+_7014064 | 3.60 |
ENST00000443597.2
|
LRRC23
|
leucine rich repeat containing 23 |
| chr12_-_22063787 | 3.60 |
ENST00000544039.1
|
ABCC9
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| chr15_+_62853562 | 3.58 |
ENST00000561311.1
|
TLN2
|
talin 2 |
| chr6_+_26402517 | 3.56 |
ENST00000414912.2
|
BTN3A1
|
butyrophilin, subfamily 3, member A1 |
| chr6_-_170101749 | 3.51 |
ENST00000448612.1
|
WDR27
|
WD repeat domain 27 |
| chr12_+_26348246 | 3.50 |
ENST00000422622.2
|
SSPN
|
sarcospan |
| chr14_-_107049312 | 3.50 |
ENST00000390627.2
|
IGHV3-53
|
immunoglobulin heavy variable 3-53 |
| chr5_+_66300446 | 3.43 |
ENST00000261569.7
|
MAST4
|
microtubule associated serine/threonine kinase family member 4 |
| chr7_+_150020363 | 3.42 |
ENST00000359623.4
ENST00000493307.1 |
LRRC61
|
leucine rich repeat containing 61 |
| chr12_+_8276224 | 3.42 |
ENST00000229332.5
|
CLEC4A
|
C-type lectin domain family 4, member A |
| chr12_-_16759711 | 3.38 |
ENST00000447609.1
|
LMO3
|
LIM domain only 3 (rhombotin-like 2) |
| chr1_+_10003486 | 3.38 |
ENST00000403197.1
ENST00000377205.1 |
NMNAT1
|
nicotinamide nucleotide adenylyltransferase 1 |
| chr3_+_115342349 | 3.37 |
ENST00000393780.3
|
GAP43
|
growth associated protein 43 |
| chr8_-_66474884 | 3.37 |
ENST00000520902.1
|
CTD-3025N20.2
|
CTD-3025N20.2 |
| chr14_-_24711865 | 3.37 |
ENST00000399423.4
ENST00000267415.7 |
TINF2
|
TERF1 (TRF1)-interacting nuclear factor 2 |
| chr14_-_24711806 | 3.35 |
ENST00000540705.1
ENST00000538777.1 ENST00000558566.1 ENST00000559019.1 |
TINF2
|
TERF1 (TRF1)-interacting nuclear factor 2 |
| chr2_+_90211643 | 3.35 |
ENST00000390277.2
|
IGKV3D-11
|
immunoglobulin kappa variable 3D-11 |
| chr5_+_36608422 | 3.29 |
ENST00000381918.3
|
SLC1A3
|
solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| chr16_-_28621312 | 3.29 |
ENST00000314752.7
|
SULT1A1
|
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| chr1_+_28199047 | 3.27 |
ENST00000373925.1
ENST00000328928.7 ENST00000373927.3 ENST00000427466.1 ENST00000442118.1 ENST00000373921.3 |
THEMIS2
|
thymocyte selection associated family member 2 |
| chr2_+_113816215 | 3.24 |
ENST00000346807.3
|
IL36RN
|
interleukin 36 receptor antagonist |
| chr1_-_38019878 | 3.21 |
ENST00000296215.6
|
SNIP1
|
Smad nuclear interacting protein 1 |
| chr17_-_2996290 | 3.18 |
ENST00000331459.1
|
OR1D2
|
olfactory receptor, family 1, subfamily D, member 2 |
| chr8_-_101571933 | 3.14 |
ENST00000520311.1
|
ANKRD46
|
ankyrin repeat domain 46 |
| chr7_+_24324726 | 3.11 |
ENST00000405982.1
|
NPY
|
neuropeptide Y |
| chr3_+_40518599 | 3.11 |
ENST00000314686.5
ENST00000447116.2 ENST00000429348.2 ENST00000456778.1 |
ZNF619
|
zinc finger protein 619 |
| chr2_-_86850949 | 3.11 |
ENST00000237455.4
|
RNF103
|
ring finger protein 103 |
| chr5_-_20575959 | 3.07 |
ENST00000507958.1
|
CDH18
|
cadherin 18, type 2 |
| chr11_+_89764274 | 3.06 |
ENST00000448984.1
ENST00000432771.1 |
TRIM49C
|
tripartite motif containing 49C |
| chr4_+_88896819 | 3.06 |
ENST00000237623.7
ENST00000395080.3 ENST00000508233.1 ENST00000360804.4 |
SPP1
|
secreted phosphoprotein 1 |
| chr12_-_48164812 | 3.05 |
ENST00000549151.1
ENST00000548919.1 |
RAPGEF3
|
Rap guanine nucleotide exchange factor (GEF) 3 |
| chr8_-_101571964 | 3.02 |
ENST00000520552.1
ENST00000521345.1 ENST00000523000.1 ENST00000335659.3 ENST00000358990.3 ENST00000519597.1 |
ANKRD46
|
ankyrin repeat domain 46 |
| chr17_+_1674982 | 3.02 |
ENST00000572048.1
ENST00000573763.1 |
SERPINF1
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| chr12_-_6233828 | 3.00 |
ENST00000572068.1
ENST00000261405.5 |
VWF
|
von Willebrand factor |
| chr17_+_67498538 | 3.00 |
ENST00000589647.1
|
MAP2K6
|
mitogen-activated protein kinase kinase 6 |
| chr1_+_50575292 | 2.93 |
ENST00000371821.1
ENST00000371819.1 |
ELAVL4
|
ELAV like neuron-specific RNA binding protein 4 |
| chr19_+_18942720 | 2.93 |
ENST00000262803.5
|
UPF1
|
UPF1 regulator of nonsense transcripts homolog (yeast) |
| chr6_-_41701581 | 2.91 |
ENST00000394283.1
|
TFEB
|
transcription factor EB |
| chr11_-_89541743 | 2.90 |
ENST00000329758.1
|
TRIM49
|
tripartite motif containing 49 |
| chr18_+_32558208 | 2.89 |
ENST00000436190.2
|
MAPRE2
|
microtubule-associated protein, RP/EB family, member 2 |
| chr7_-_130080818 | 2.88 |
ENST00000343969.5
ENST00000541543.1 ENST00000489512.1 |
CEP41
|
centrosomal protein 41kDa |
| chr2_-_201729284 | 2.86 |
ENST00000434813.2
|
CLK1
|
CDC-like kinase 1 |
| chr20_-_56265680 | 2.85 |
ENST00000414037.1
|
PMEPA1
|
prostate transmembrane protein, androgen induced 1 |
| chr15_+_58702742 | 2.83 |
ENST00000356113.6
ENST00000414170.3 |
LIPC
|
lipase, hepatic |
| chr10_-_115904361 | 2.81 |
ENST00000428953.1
ENST00000543782.1 |
C10orf118
|
chromosome 10 open reading frame 118 |
| chr12_+_7013897 | 2.77 |
ENST00000007969.8
ENST00000323702.5 |
LRRC23
|
leucine rich repeat containing 23 |
| chrX_-_14047996 | 2.76 |
ENST00000380523.4
ENST00000398355.3 |
GEMIN8
|
gem (nuclear organelle) associated protein 8 |
| chr3_-_33686743 | 2.73 |
ENST00000333778.6
ENST00000539981.1 |
CLASP2
|
cytoplasmic linker associated protein 2 |
| chr6_+_89674246 | 2.67 |
ENST00000369474.1
|
AL079342.1
|
Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741 |
| chr12_+_8276433 | 2.63 |
ENST00000345999.3
ENST00000352620.3 ENST00000360500.3 |
CLEC4A
|
C-type lectin domain family 4, member A |
| chr16_+_31271274 | 2.62 |
ENST00000287497.8
ENST00000544665.3 |
ITGAM
|
integrin, alpha M (complement component 3 receptor 3 subunit) |
| chr11_-_63376013 | 2.59 |
ENST00000540943.1
|
PLA2G16
|
phospholipase A2, group XVI |
| chr2_-_201729393 | 2.59 |
ENST00000321356.4
|
CLK1
|
CDC-like kinase 1 |
| chr14_-_24711470 | 2.57 |
ENST00000559969.1
|
TINF2
|
TERF1 (TRF1)-interacting nuclear factor 2 |
| chr2_-_90538397 | 2.56 |
ENST00000443397.3
|
RP11-685N3.1
|
Uncharacterized protein |
| chr4_-_185275104 | 2.55 |
ENST00000317596.3
|
RP11-290F5.2
|
RP11-290F5.2 |
| chr10_-_28571015 | 2.52 |
ENST00000375719.3
ENST00000375732.1 |
MPP7
|
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) |
| chr2_+_90248739 | 2.51 |
ENST00000468879.1
|
IGKV1D-43
|
immunoglobulin kappa variable 1D-43 |
| chr9_-_5339873 | 2.47 |
ENST00000223862.1
ENST00000223858.4 |
RLN1
|
relaxin 1 |
| chr10_+_18549645 | 2.47 |
ENST00000396576.2
|
CACNB2
|
calcium channel, voltage-dependent, beta 2 subunit |
| chr20_+_3801162 | 2.46 |
ENST00000379573.2
ENST00000379567.2 ENST00000455742.1 ENST00000246041.2 |
AP5S1
|
adaptor-related protein complex 5, sigma 1 subunit |
| chr11_+_24518723 | 2.45 |
ENST00000336930.6
ENST00000529015.1 ENST00000533227.1 |
LUZP2
|
leucine zipper protein 2 |
| chr9_-_100684845 | 2.44 |
ENST00000375119.3
|
C9orf156
|
chromosome 9 open reading frame 156 |
| chr19_+_42817527 | 2.42 |
ENST00000598766.1
|
TMEM145
|
transmembrane protein 145 |
| chr2_+_87565634 | 2.41 |
ENST00000421835.2
|
IGKV3OR2-268
|
immunoglobulin kappa variable 3/OR2-268 (non-functional) |
| chr11_-_13517565 | 2.40 |
ENST00000282091.1
ENST00000529816.1 |
PTH
|
parathyroid hormone |
| chr8_-_86253888 | 2.40 |
ENST00000522389.1
ENST00000432364.2 ENST00000517618.1 |
CA1
|
carbonic anhydrase I |
| chr2_+_79412357 | 2.36 |
ENST00000466387.1
|
CTNNA2
|
catenin (cadherin-associated protein), alpha 2 |
| chr2_-_89327228 | 2.32 |
ENST00000483158.1
|
IGKV3-11
|
immunoglobulin kappa variable 3-11 |
| chr18_+_46065393 | 2.30 |
ENST00000256413.3
|
CTIF
|
CBP80/20-dependent translation initiation factor |
| chr19_+_9296279 | 2.29 |
ENST00000344248.2
|
OR7D2
|
olfactory receptor, family 7, subfamily D, member 2 |
| chr11_+_5710919 | 2.28 |
ENST00000379965.3
ENST00000425490.1 |
TRIM22
|
tripartite motif containing 22 |
| chr2_+_113816685 | 2.28 |
ENST00000393200.2
|
IL36RN
|
interleukin 36 receptor antagonist |
| chr1_+_84609944 | 2.24 |
ENST00000370685.3
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr8_-_86290333 | 2.24 |
ENST00000521846.1
ENST00000523022.1 ENST00000524324.1 ENST00000519991.1 ENST00000520663.1 ENST00000517590.1 ENST00000522579.1 ENST00000522814.1 ENST00000522662.1 ENST00000523858.1 ENST00000519129.1 |
CA1
|
carbonic anhydrase I |
| chr6_+_26402465 | 2.19 |
ENST00000476549.2
ENST00000289361.6 ENST00000450085.2 ENST00000425234.2 ENST00000427334.1 ENST00000506698.1 |
BTN3A1
|
butyrophilin, subfamily 3, member A1 |
| chr5_+_150404904 | 2.19 |
ENST00000521632.1
|
GPX3
|
glutathione peroxidase 3 (plasma) |
| chr1_+_101003687 | 2.17 |
ENST00000315033.4
|
GPR88
|
G protein-coupled receptor 88 |
| chr2_+_68592305 | 2.15 |
ENST00000234313.7
|
PLEK
|
pleckstrin |
| chr16_+_33020496 | 2.12 |
ENST00000565407.2
|
IGHV3OR16-8
|
immunoglobulin heavy variable 3/OR16-8 (non-functional) |
| chr1_-_150738261 | 2.11 |
ENST00000448301.2
ENST00000368985.3 |
CTSS
|
cathepsin S |
| chr11_+_59824060 | 2.10 |
ENST00000395032.2
ENST00000358152.2 |
MS4A3
|
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
| chr13_+_31309645 | 2.08 |
ENST00000380490.3
|
ALOX5AP
|
arachidonate 5-lipoxygenase-activating protein |
| chr12_-_15114492 | 2.03 |
ENST00000541546.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr11_+_59824127 | 2.03 |
ENST00000278865.3
|
MS4A3
|
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
| chr12_-_112123524 | 2.02 |
ENST00000327551.6
|
BRAP
|
BRCA1 associated protein |
| chr2_-_89442621 | 1.99 |
ENST00000492167.1
|
IGKV3-20
|
immunoglobulin kappa variable 3-20 |
| chr18_-_5540471 | 1.97 |
ENST00000581833.1
ENST00000544123.1 ENST00000342933.3 ENST00000400111.3 ENST00000585142.1 |
EPB41L3
|
erythrocyte membrane protein band 4.1-like 3 |
| chr2_+_191792376 | 1.96 |
ENST00000409428.1
ENST00000409215.1 |
GLS
|
glutaminase |
| chr1_+_168148273 | 1.96 |
ENST00000367830.3
|
TIPRL
|
TIP41, TOR signaling pathway regulator-like (S. cerevisiae) |
| chr3_-_194072019 | 1.94 |
ENST00000429275.1
ENST00000323830.3 |
CPN2
|
carboxypeptidase N, polypeptide 2 |
| chr3_-_151047327 | 1.93 |
ENST00000325602.5
|
P2RY13
|
purinergic receptor P2Y, G-protein coupled, 13 |
| chr19_-_42746714 | 1.92 |
ENST00000222330.3
|
GSK3A
|
glycogen synthase kinase 3 alpha |
| chr14_-_106552755 | 1.92 |
ENST00000390600.2
|
IGHV3-9
|
immunoglobulin heavy variable 3-9 |
| chr14_-_106926724 | 1.91 |
ENST00000434710.1
|
IGHV3-43
|
immunoglobulin heavy variable 3-43 |
| chr16_-_28621298 | 1.91 |
ENST00000566189.1
|
SULT1A1
|
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| chr9_-_99540328 | 1.90 |
ENST00000223428.4
ENST00000375231.1 ENST00000374641.3 |
ZNF510
|
zinc finger protein 510 |
| chr8_-_110986918 | 1.89 |
ENST00000297404.1
|
KCNV1
|
potassium channel, subfamily V, member 1 |
| chr19_-_19302931 | 1.89 |
ENST00000444486.3
ENST00000514819.3 ENST00000585679.1 ENST00000162023.5 |
MEF2BNB-MEF2B
MEF2BNB
MEF2B
|
MEF2BNB-MEF2B readthrough MEF2B neighbor myocyte enhancer factor 2B |
| chr14_-_78083112 | 1.86 |
ENST00000216484.2
|
SPTLC2
|
serine palmitoyltransferase, long chain base subunit 2 |
| chr3_+_121774202 | 1.86 |
ENST00000469710.1
ENST00000493101.1 ENST00000330540.2 ENST00000264468.5 |
CD86
|
CD86 molecule |
| chr7_-_150020578 | 1.85 |
ENST00000478393.1
|
ACTR3C
|
ARP3 actin-related protein 3 homolog C (yeast) |
| chr7_-_105029812 | 1.83 |
ENST00000482897.1
|
SRPK2
|
SRSF protein kinase 2 |
| chr6_-_52705641 | 1.83 |
ENST00000370989.2
|
GSTA5
|
glutathione S-transferase alpha 5 |
| chr17_-_6983550 | 1.80 |
ENST00000576617.1
ENST00000416562.2 |
CLEC10A
|
C-type lectin domain family 10, member A |
| chr1_-_211307404 | 1.78 |
ENST00000367007.4
|
KCNH1
|
potassium voltage-gated channel, subfamily H (eag-related), member 1 |
| chr2_+_196313239 | 1.76 |
ENST00000413290.1
|
AC064834.1
|
AC064834.1 |
| chr21_+_43619796 | 1.75 |
ENST00000398457.2
|
ABCG1
|
ATP-binding cassette, sub-family G (WHITE), member 1 |
| chr16_+_48278178 | 1.74 |
ENST00000285737.4
ENST00000535754.1 |
LONP2
|
lon peptidase 2, peroxisomal |
| chr3_+_152552685 | 1.72 |
ENST00000305097.3
|
P2RY1
|
purinergic receptor P2Y, G-protein coupled, 1 |
| chr1_-_150669604 | 1.72 |
ENST00000427665.1
ENST00000540514.1 |
GOLPH3L
|
golgi phosphoprotein 3-like |
| chr5_+_161274685 | 1.72 |
ENST00000428797.2
|
GABRA1
|
gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
| chr15_+_58430567 | 1.71 |
ENST00000536493.1
|
AQP9
|
aquaporin 9 |
| chr16_-_28608364 | 1.71 |
ENST00000533150.1
|
SULT1A2
|
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| chr11_+_119076745 | 1.70 |
ENST00000264033.4
|
CBL
|
Cbl proto-oncogene, E3 ubiquitin protein ligase |
| chr1_+_50569575 | 1.68 |
ENST00000371827.1
|
ELAVL4
|
ELAV like neuron-specific RNA binding protein 4 |
| chr15_-_55657428 | 1.68 |
ENST00000568543.1
|
CCPG1
|
cell cycle progression 1 |
| chr9_+_90112767 | 1.68 |
ENST00000408954.3
|
DAPK1
|
death-associated protein kinase 1 |
| chr19_-_14785622 | 1.68 |
ENST00000443157.2
|
EMR3
|
egf-like module containing, mucin-like, hormone receptor-like 3 |
| chr2_-_74618964 | 1.67 |
ENST00000417090.1
ENST00000409868.1 |
DCTN1
|
dynactin 1 |
| chr3_+_195447738 | 1.67 |
ENST00000447234.2
ENST00000320736.6 ENST00000436408.1 |
MUC20
|
mucin 20, cell surface associated |
| chr3_-_160823158 | 1.67 |
ENST00000392779.2
ENST00000392780.1 ENST00000494173.1 |
B3GALNT1
|
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) |
| chr10_+_96522361 | 1.65 |
ENST00000371321.3
|
CYP2C19
|
cytochrome P450, family 2, subfamily C, polypeptide 19 |
| chr12_-_8088871 | 1.63 |
ENST00000075120.7
|
SLC2A3
|
solute carrier family 2 (facilitated glucose transporter), member 3 |
| chr9_+_90112590 | 1.63 |
ENST00000472284.1
|
DAPK1
|
death-associated protein kinase 1 |
| chr18_+_32173276 | 1.62 |
ENST00000591816.1
ENST00000588125.1 ENST00000598334.1 ENST00000588684.1 ENST00000554864.3 ENST00000399121.5 ENST00000595022.1 ENST00000269190.7 ENST00000399097.3 |
DTNA
|
dystrobrevin, alpha |
| chr3_-_112127981 | 1.61 |
ENST00000486726.2
|
RP11-231E6.1
|
RP11-231E6.1 |
| chr5_-_41213607 | 1.60 |
ENST00000337836.5
ENST00000433294.1 |
C6
|
complement component 6 |
| chr11_+_94706973 | 1.60 |
ENST00000536741.1
|
KDM4D
|
lysine (K)-specific demethylase 4D |
| chr4_-_11431188 | 1.60 |
ENST00000510712.1
|
HS3ST1
|
heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| chr19_+_42746927 | 1.60 |
ENST00000378108.1
|
AC006486.1
|
AC006486.1 |
| chr11_+_71900572 | 1.60 |
ENST00000312293.4
|
FOLR1
|
folate receptor 1 (adult) |
| chrX_-_130423200 | 1.59 |
ENST00000361420.3
|
IGSF1
|
immunoglobulin superfamily, member 1 |
| chr1_-_160549235 | 1.58 |
ENST00000368054.3
ENST00000368048.3 ENST00000311224.4 ENST00000368051.3 ENST00000534968.1 |
CD84
|
CD84 molecule |
| chr4_+_56814968 | 1.58 |
ENST00000422247.2
|
CEP135
|
centrosomal protein 135kDa |
| chrX_-_138724994 | 1.56 |
ENST00000536274.1
|
MCF2
|
MCF.2 cell line derived transforming sequence |
| chr7_+_150020329 | 1.56 |
ENST00000323078.7
|
LRRC61
|
leucine rich repeat containing 61 |
| chr12_-_23737534 | 1.54 |
ENST00000396007.2
|
SOX5
|
SRY (sex determining region Y)-box 5 |
| chrX_+_43515467 | 1.52 |
ENST00000338702.3
ENST00000542639.1 |
MAOA
|
monoamine oxidase A |
Network of associatons between targets according to the STRING database.
First level regulatory network of DLX1_HOXA3_BARX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.7 | 17.1 | GO:2001190 | positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190) |
| 3.3 | 23.1 | GO:0002414 | immunoglobulin transcytosis in epithelial cells(GO:0002414) |
| 3.1 | 9.2 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 3.0 | 9.0 | GO:1902948 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 2.8 | 8.5 | GO:0002881 | negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881) |
| 2.6 | 7.7 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 2.4 | 7.1 | GO:0000294 | nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) |
| 2.2 | 8.7 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 1.8 | 17.6 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 1.7 | 12.1 | GO:0048241 | epinephrine transport(GO:0048241) |
| 1.6 | 6.2 | GO:0010900 | negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
| 1.5 | 9.3 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 1.3 | 4.0 | GO:1990168 | protein K33-linked deubiquitination(GO:1990168) |
| 1.0 | 3.1 | GO:2000861 | estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
| 1.0 | 3.0 | GO:0003147 | neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) |
| 1.0 | 3.0 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.9 | 6.8 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.8 | 4.2 | GO:1902714 | negative regulation of interferon-gamma secretion(GO:1902714) |
| 0.8 | 5.7 | GO:0006537 | glutamate biosynthetic process(GO:0006537) |
| 0.8 | 2.4 | GO:1900158 | hormone-mediated apoptotic signaling pathway(GO:0008628) positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
| 0.8 | 4.0 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 0.8 | 19.1 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.8 | 3.0 | GO:0030822 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123) |
| 0.8 | 5.3 | GO:2000332 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.7 | 3.7 | GO:0048539 | immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539) |
| 0.7 | 2.2 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
| 0.7 | 4.2 | GO:1903301 | fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.7 | 5.5 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.6 | 1.9 | GO:0006258 | UDP-glucose catabolic process(GO:0006258) |
| 0.6 | 2.5 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 0.6 | 1.9 | GO:0042109 | negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 0.6 | 1.7 | GO:0009726 | detection of endogenous stimulus(GO:0009726) |
| 0.6 | 44.4 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.6 | 1.7 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
| 0.6 | 3.4 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.5 | 1.6 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.5 | 2.2 | GO:0061743 | motor learning(GO:0061743) |
| 0.5 | 6.3 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.5 | 3.1 | GO:0032097 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
| 0.5 | 2.6 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.5 | 1.0 | GO:0046502 | uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502) |
| 0.5 | 2.9 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.5 | 1.4 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 0.5 | 1.9 | GO:1904504 | regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504) |
| 0.4 | 2.2 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.4 | 6.5 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.4 | 5.6 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 0.4 | 0.8 | GO:2000366 | regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366) |
| 0.4 | 2.5 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.4 | 1.6 | GO:0001970 | positive regulation of activation of membrane attack complex(GO:0001970) |
| 0.4 | 4.1 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.4 | 3.4 | GO:0006531 | aspartate metabolic process(GO:0006531) |
| 0.4 | 2.6 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.4 | 0.7 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.4 | 1.8 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.4 | 2.5 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.4 | 2.1 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 0.3 | 5.5 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.3 | 2.7 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.3 | 1.0 | GO:0006114 | glycerol biosynthetic process(GO:0006114) |
| 0.3 | 3.4 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.3 | 1.7 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.3 | 1.0 | GO:2000295 | regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.3 | 1.6 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.3 | 1.6 | GO:0032661 | regulation of interleukin-18 production(GO:0032661) |
| 0.3 | 1.3 | GO:2001027 | negative regulation of endothelial cell chemotaxis(GO:2001027) |
| 0.3 | 0.9 | GO:0036058 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 0.3 | 1.8 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.3 | 0.9 | GO:0001812 | positive regulation of type I hypersensitivity(GO:0001812) |
| 0.3 | 5.3 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.3 | 1.5 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.3 | 6.7 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.3 | 0.9 | GO:0048382 | mesendoderm development(GO:0048382) |
| 0.3 | 0.3 | GO:0060369 | positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.3 | 0.8 | GO:0071301 | cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404) |
| 0.3 | 10.2 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.3 | 4.9 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.3 | 0.8 | GO:2000048 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.3 | 1.5 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.3 | 0.8 | GO:0051697 | protein delipidation(GO:0051697) |
| 0.3 | 1.8 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.3 | 1.3 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.3 | 1.5 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.2 | 0.7 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.2 | 2.9 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.2 | 2.7 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.2 | 1.7 | GO:0090650 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.2 | 0.7 | GO:0052331 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 0.2 | 2.8 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.2 | 1.4 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.2 | 4.2 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.2 | 0.9 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.2 | 2.1 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.2 | 0.7 | GO:0030309 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.2 | 1.1 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.2 | 1.1 | GO:0015860 | purine nucleoside transmembrane transport(GO:0015860) |
| 0.2 | 1.7 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.2 | 0.6 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
| 0.2 | 0.8 | GO:0048762 | mesenchymal cell development(GO:0014031) mesenchymal cell differentiation(GO:0048762) |
| 0.2 | 0.6 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.2 | 4.0 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.2 | 1.2 | GO:0035672 | oligopeptide transmembrane transport(GO:0035672) |
| 0.2 | 0.8 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.2 | 0.6 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) |
| 0.2 | 28.2 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.2 | 0.4 | GO:0046110 | xanthine metabolic process(GO:0046110) |
| 0.2 | 2.6 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.2 | 0.7 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.2 | 2.4 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.2 | 0.5 | GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) |
| 0.2 | 0.9 | GO:0072023 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 0.2 | 1.0 | GO:0046487 | proline catabolic process to glutamate(GO:0010133) glyoxylate metabolic process(GO:0046487) |
| 0.2 | 1.0 | GO:0001878 | response to yeast(GO:0001878) |
| 0.2 | 0.7 | GO:0050712 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
| 0.2 | 1.5 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.2 | 1.2 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.2 | 5.1 | GO:0002820 | negative regulation of adaptive immune response(GO:0002820) |
| 0.2 | 0.8 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 0.1 | 3.0 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.1 | 1.5 | GO:0051791 | medium-chain fatty acid metabolic process(GO:0051791) |
| 0.1 | 0.4 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.1 | 1.3 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.1 | 2.4 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.1 | 1.3 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 1.1 | GO:2000400 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.1 | 0.3 | GO:0002329 | pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331) |
| 0.1 | 0.3 | GO:0019474 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 0.1 | 3.8 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.1 | 0.4 | GO:0043105 | regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105) |
| 0.1 | 5.6 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.1 | 0.4 | GO:0090611 | mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 0.1 | 4.4 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.1 | 0.7 | GO:0072502 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 0.6 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 0.1 | 1.1 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.1 | 1.7 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
| 0.1 | 0.3 | GO:1902161 | positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) |
| 0.1 | 0.8 | GO:1902947 | regulation of tau-protein kinase activity(GO:1902947) |
| 0.1 | 2.2 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.1 | 1.0 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.1 | 1.4 | GO:0090220 | meiotic telomere clustering(GO:0045141) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) |
| 0.1 | 0.8 | GO:1990592 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.1 | 2.8 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.1 | 0.4 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961) |
| 0.1 | 0.3 | GO:0072098 | apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
| 0.1 | 0.7 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.1 | 3.8 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.1 | 2.2 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.1 | 0.7 | GO:2000773 | negative regulation of cellular senescence(GO:2000773) |
| 0.1 | 0.8 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.1 | 1.7 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.1 | 5.0 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.1 | 3.6 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 2.0 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 2.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 1.8 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.1 | 2.1 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.1 | 0.8 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.1 | 1.1 | GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.1 | 1.4 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.1 | 1.2 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.1 | 15.1 | GO:0002223 | stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
| 0.1 | 0.3 | GO:1904383 | response to sodium phosphate(GO:1904383) response to insulin-like growth factor stimulus(GO:1990418) |
| 0.1 | 0.2 | GO:1902573 | positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573) |
| 0.1 | 0.5 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.1 | 0.9 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 9.9 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
| 0.1 | 1.2 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 0.1 | 0.9 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.1 | 0.7 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.1 | 1.3 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.1 | 3.2 | GO:0050776 | regulation of immune response(GO:0050776) |
| 0.1 | 0.4 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 0.1 | 0.3 | GO:0042492 | gamma-delta T cell differentiation(GO:0042492) |
| 0.1 | 1.5 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
| 0.1 | 0.3 | GO:0050955 | thermoception(GO:0050955) |
| 0.1 | 1.0 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.1 | 0.6 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.1 | 2.9 | GO:0007040 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.1 | 0.8 | GO:0001787 | natural killer cell proliferation(GO:0001787) |
| 0.1 | 8.3 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.1 | 0.9 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 3.2 | GO:0050852 | T cell receptor signaling pathway(GO:0050852) |
| 0.1 | 1.8 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.1 | 0.4 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.1 | 0.2 | GO:0060133 | somatotropin secreting cell development(GO:0060133) |
| 0.1 | 0.5 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.1 | 1.3 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.1 | 1.1 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 1.1 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
| 0.0 | 1.1 | GO:0045087 | innate immune response(GO:0045087) |
| 0.0 | 0.1 | GO:0071436 | sodium ion export(GO:0071436) |
| 0.0 | 0.6 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 0.1 | GO:0060748 | tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) |
| 0.0 | 2.3 | GO:0070206 | protein trimerization(GO:0070206) |
| 0.0 | 1.0 | GO:0007601 | visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953) |
| 0.0 | 1.2 | GO:0051480 | regulation of cytosolic calcium ion concentration(GO:0051480) |
| 0.0 | 2.3 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 1.4 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.0 | 0.2 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
| 0.0 | 1.0 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.0 | 1.1 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 0.5 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.0 | 0.2 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.0 | 0.9 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 1.5 | GO:0035036 | sperm-egg recognition(GO:0035036) |
| 0.0 | 0.9 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 1.4 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.0 | 0.2 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.0 | 0.4 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.1 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.0 | 0.3 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.0 | 1.3 | GO:0019835 | cytolysis(GO:0019835) |
| 0.0 | 3.9 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 0.0 | 0.7 | GO:0039694 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.0 | 1.3 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.0 | 0.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 0.6 | GO:0010762 | regulation of fibroblast migration(GO:0010762) |
| 0.0 | 0.3 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.0 | 1.5 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.0 | 0.6 | GO:0015813 | L-glutamate transport(GO:0015813) |
| 0.0 | 1.8 | GO:0038095 | Fc-epsilon receptor signaling pathway(GO:0038095) |
| 0.0 | 1.3 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
| 0.0 | 1.0 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.0 | 9.5 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 0.0 | 0.8 | GO:0030449 | regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257) |
| 0.0 | 0.1 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.0 | 5.8 | GO:0000086 | G2/M transition of mitotic cell cycle(GO:0000086) |
| 0.0 | 0.8 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.3 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.0 | 0.4 | GO:0030220 | platelet formation(GO:0030220) |
| 0.0 | 0.2 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.0 | 0.4 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 3.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.1 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.0 | 0.3 | GO:0009408 | response to heat(GO:0009408) |
| 0.0 | 0.2 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.0 | 2.2 | GO:0042113 | B cell activation(GO:0042113) |
| 0.0 | 2.5 | GO:0016197 | endosomal transport(GO:0016197) |
| 0.0 | 0.1 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.0 | 0.4 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 0.1 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.0 | 0.2 | GO:0032196 | transposition(GO:0032196) |
| 0.0 | 0.0 | GO:1901994 | meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 0.0 | 0.8 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.0 | 0.6 | GO:0002456 | T cell mediated immunity(GO:0002456) |
| 0.0 | 2.4 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.2 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.0 | 2.4 | GO:0007565 | female pregnancy(GO:0007565) |
| 0.0 | 0.6 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.0 | 6.0 | GO:0006897 | endocytosis(GO:0006897) |
| 0.0 | 0.5 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.0 | 0.2 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.6 | GO:0016079 | synaptic vesicle exocytosis(GO:0016079) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 9.3 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 1.7 | 11.6 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 1.4 | 7.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 1.2 | 3.6 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.8 | 17.1 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.7 | 2.0 | GO:0071745 | IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751) |
| 0.6 | 9.0 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.5 | 2.6 | GO:0034688 | integrin alphaM-beta2 complex(GO:0034688) |
| 0.5 | 3.4 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.5 | 8.0 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.5 | 1.9 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.4 | 1.1 | GO:0036030 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 0.4 | 11.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.3 | 6.5 | GO:0031045 | dense core granule(GO:0031045) |
| 0.3 | 2.7 | GO:0045180 | basal cortex(GO:0045180) |
| 0.3 | 3.8 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.3 | 2.1 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.3 | 8.5 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.3 | 4.2 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.3 | 3.0 | GO:0043203 | axon hillock(GO:0043203) |
| 0.3 | 1.0 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.3 | 3.0 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.2 | 5.4 | GO:0042627 | chylomicron(GO:0042627) |
| 0.2 | 2.0 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.2 | 10.0 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.2 | 4.2 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.2 | 2.5 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.2 | 3.0 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.2 | 4.0 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.2 | 2.5 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.2 | 1.6 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.2 | 1.6 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.2 | 5.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.2 | 40.5 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.2 | 1.4 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.2 | 5.4 | GO:0090665 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.2 | 1.7 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.2 | 0.9 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.1 | 0.6 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.1 | 1.9 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.1 | 0.9 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 0.6 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.1 | 1.3 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.1 | 2.4 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 2.2 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 0.8 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.1 | 0.9 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.1 | 0.6 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.1 | 0.4 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 1.8 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 1.7 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.1 | 5.7 | GO:0031672 | A band(GO:0031672) |
| 0.1 | 1.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 2.5 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 5.9 | GO:0005902 | microvillus(GO:0005902) |
| 0.1 | 1.4 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.1 | 1.1 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 12.1 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 0.3 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.1 | 2.4 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 0.4 | GO:0090543 | Flemming body(GO:0090543) |
| 0.1 | 17.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 5.8 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 1.7 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.1 | 6.0 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.1 | 0.9 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 1.6 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 0.8 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 0.2 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.0 | 0.8 | GO:0030666 | endocytic vesicle membrane(GO:0030666) |
| 0.0 | 3.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.0 | 1.5 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 1.9 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.7 | GO:0036019 | endolysosome(GO:0036019) |
| 0.0 | 0.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 9.8 | GO:0045121 | membrane raft(GO:0045121) |
| 0.0 | 2.3 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.2 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.0 | 1.5 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 10.6 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 1.7 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 4.2 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.7 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.9 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.1 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.0 | 39.5 | GO:0031226 | intrinsic component of plasma membrane(GO:0031226) |
| 0.0 | 0.7 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 1.5 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 2.8 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.4 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 2.1 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 0.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.7 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 1.0 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 1.1 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.6 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 23.1 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 0.2 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 0.7 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.9 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.4 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.2 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 2.2 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 0.4 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 1.3 | GO:0099503 | secretory granule(GO:0030141) secretory vesicle(GO:0099503) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.8 | 23.1 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 3.0 | 12.1 | GO:0005277 | acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375) |
| 2.8 | 8.5 | GO:0016495 | C-X3-C chemokine receptor activity(GO:0016495) |
| 2.7 | 18.6 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 2.3 | 11.6 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 1.5 | 9.2 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 1.3 | 4.0 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 1.1 | 6.8 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 1.1 | 3.4 | GO:0004515 | nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 1.1 | 5.5 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 1.1 | 5.5 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 1.0 | 3.0 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 0.9 | 5.3 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.9 | 8.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.8 | 43.9 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.8 | 6.2 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.8 | 3.0 | GO:0061714 | folic acid receptor activity(GO:0061714) |
| 0.7 | 4.2 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.7 | 2.1 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.6 | 1.9 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.6 | 11.7 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.6 | 1.7 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 0.6 | 4.6 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.6 | 17.1 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.5 | 1.6 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.5 | 2.6 | GO:0052740 | 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 0.5 | 1.5 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.5 | 1.4 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.5 | 1.4 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.5 | 3.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.4 | 1.7 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.4 | 1.7 | GO:0015254 | glycerol channel activity(GO:0015254) urea channel activity(GO:0015265) |
| 0.4 | 1.2 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.4 | 2.0 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.4 | 2.5 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.3 | 1.7 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.3 | 6.1 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.3 | 1.0 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.3 | 3.4 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.3 | 1.3 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.3 | 3.9 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.3 | 1.0 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 0.3 | 1.6 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.3 | 1.2 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.3 | 1.8 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.3 | 1.5 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.3 | 0.8 | GO:0061663 | NEDD8 ligase activity(GO:0061663) |
| 0.3 | 1.4 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.3 | 8.0 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.3 | 0.8 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.3 | 1.6 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.3 | 1.1 | GO:0005415 | nucleoside:sodium symporter activity(GO:0005415) |
| 0.3 | 2.6 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 0.3 | 3.1 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.3 | 1.0 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.2 | 0.7 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.2 | 1.4 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.2 | 3.0 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.2 | 12.0 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.2 | 4.0 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.2 | 0.9 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.2 | 0.7 | GO:0008532 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) |
| 0.2 | 1.1 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.2 | 0.9 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.2 | 1.7 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.2 | 5.8 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 1.7 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.2 | 0.8 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
| 0.2 | 2.2 | GO:0008430 | selenium binding(GO:0008430) |
| 0.2 | 1.6 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.2 | 1.0 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.2 | 4.8 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.2 | 1.5 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.2 | 37.4 | GO:0003823 | antigen binding(GO:0003823) |
| 0.2 | 0.7 | GO:0035473 | lipase binding(GO:0035473) |
| 0.2 | 0.7 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.2 | 7.6 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.2 | 5.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 1.7 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.2 | 1.0 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.2 | 2.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.2 | 39.2 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.2 | 4.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.2 | 2.7 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.1 | 0.7 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.1 | 0.9 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.1 | 2.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 0.9 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.1 | 3.2 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 5.6 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 0.7 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.1 | 0.6 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.1 | 0.4 | GO:0044549 | GTP cyclohydrolase binding(GO:0044549) |
| 0.1 | 8.4 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.1 | 6.8 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.1 | 1.1 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.1 | 4.8 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 0.6 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 0.5 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.1 | 3.9 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 0.9 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.1 | 0.4 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.1 | 0.4 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.1 | 3.1 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.4 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.1 | 2.1 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 0.3 | GO:0046848 | hydroxyapatite binding(GO:0046848) |
| 0.1 | 1.4 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 0.5 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.1 | 1.6 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.1 | 0.7 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.1 | 2.3 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 0.4 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 0.1 | 3.0 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 4.9 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.8 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.1 | 0.2 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.1 | 0.1 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 0.3 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.1 | 0.4 | GO:0030345 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.1 | 0.8 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.1 | 1.3 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 0.8 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.1 | 2.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 1.1 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.1 | 0.8 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 1.0 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 1.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 1.8 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 1.0 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 0.5 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.1 | 1.2 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 0.9 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 1.8 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.1 | 0.4 | GO:0097200 | cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.1 | 0.5 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.1 | 5.3 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.1 | 0.8 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 1.9 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.1 | 1.0 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.1 | 1.1 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.1 | 0.2 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 0.2 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 0.1 | 2.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 0.6 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.1 | 2.1 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.1 | 0.6 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.0 | 1.3 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 0.2 | GO:0042019 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.0 | 1.9 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 1.4 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 0.1 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.0 | 0.3 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 0.3 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.0 | 2.3 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 4.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 2.6 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 14.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.8 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 9.7 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.4 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 0.3 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.0 | 1.1 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 4.3 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 0.2 | GO:0015094 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.0 | 0.6 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 3.8 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.7 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.0 | 9.2 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 2.4 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.3 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 1.7 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.8 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
| 0.0 | 0.8 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.6 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.0 | 1.7 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 2.0 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 1.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.8 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.6 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.0 | 3.8 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 0.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 1.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.1 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.0 | 0.1 | GO:0046906 | tetrapyrrole binding(GO:0046906) |
| 0.0 | 1.1 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 1.0 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.0 | 1.2 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 0.0 | 2.0 | GO:0060090 | binding, bridging(GO:0060090) |
| 0.0 | 0.1 | GO:0016615 | malate dehydrogenase activity(GO:0016615) |
| 0.0 | 2.5 | GO:0008047 | enzyme activator activity(GO:0008047) |
| 0.0 | 0.5 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.1 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.3 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.2 | 0.7 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.2 | 3.0 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 6.8 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.1 | 24.5 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 1.8 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 7.1 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.1 | 0.9 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 8.8 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 3.8 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 3.2 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 6.4 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.1 | 6.1 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.1 | 1.8 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 5.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 1.5 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 0.2 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 2.6 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 1.7 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 1.3 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 2.0 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 1.1 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.1 | 1.9 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 6.2 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 3.6 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.1 | 2.2 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.6 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 1.0 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.4 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 0.6 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 0.8 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 0.7 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.4 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 0.1 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 0.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.5 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 0.9 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.7 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.6 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 0.6 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 3.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.2 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.2 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 0.3 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 13.6 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.7 | 18.6 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.4 | 5.4 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.3 | 6.8 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.3 | 4.6 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.3 | 5.6 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.2 | 3.8 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.2 | 4.9 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.2 | 4.2 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.2 | 2.1 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.2 | 1.9 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.2 | 9.8 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 3.0 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.2 | 2.0 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.2 | 2.8 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.2 | 2.6 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.2 | 4.4 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.2 | 5.7 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.2 | 9.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 18.4 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 3.7 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.1 | 5.3 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 2.7 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 5.5 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 1.7 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 2.2 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 1.7 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.1 | 0.6 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.1 | 1.4 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.1 | 4.2 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 1.5 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.1 | 5.8 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 11.2 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 2.8 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 1.6 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.1 | 1.6 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 3.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 0.8 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.1 | 4.0 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 3.5 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 1.7 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
| 0.1 | 0.7 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 5.7 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 1.2 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.1 | 1.2 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.1 | 0.9 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.1 | 2.5 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.1 | 0.4 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 3.4 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.1 | 9.1 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 1.1 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 1.7 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 1.6 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 3.4 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 0.6 | REACTOME G ALPHA1213 SIGNALLING EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.1 | 1.1 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 1.8 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.8 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 1.0 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.4 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 2.2 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.0 | 0.6 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 1.2 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 1.0 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 1.0 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 1.4 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.6 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 0.4 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.0 | 0.9 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.9 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 0.1 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.0 | 3.2 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.5 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 0.2 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.0 | 0.6 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.4 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.7 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 0.7 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.4 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 0.7 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.2 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 1.4 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.9 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.0 | 0.1 | REACTOME OPSINS | Genes involved in Opsins |