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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for E2F3

Z-value: 3.18

Motif logo

Transcription factors associated with E2F3

Gene Symbol Gene ID Gene Info
ENSG00000112242.10 E2F transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F3hg19_v2_chr6_+_20403997_204040340.593.8e-22Click!

Activity profile of E2F3 motif

Sorted Z-values of E2F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_91537723 68.65 ENST00000394249.3
ENST00000559811.1
ENST00000442656.2
ENST00000557905.1
ENST00000361919.3
protein regulator of cytokinesis 1
chr17_+_73201754 63.43 ENST00000583569.1
ENST00000245544.4
ENST00000579324.1
ENST00000541827.1
ENST00000579298.1
ENST00000447371.2
nucleoporin 85kDa
chr10_-_58120996 54.71 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZW10 interacting kinetochore protein
chr5_+_177631497 46.01 ENST00000358344.3
heterogeneous nuclear ribonucleoprotein A/B
chr2_+_10262857 44.05 ENST00000304567.5
ribonucleotide reductase M2
chr10_+_62538248 42.45 ENST00000448257.2
cyclin-dependent kinase 1
chr18_-_54318353 41.49 ENST00000590954.1
ENST00000540155.1
thioredoxin-like 1
chr20_+_25388293 41.20 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr10_+_62538089 39.75 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr19_-_55919087 39.55 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
ubiquitin-conjugating enzyme E2S
chr3_+_112709804 38.25 ENST00000383677.3
GTP-binding protein 8 (putative)
chr6_-_38670897 36.93 ENST00000373365.4
glyoxalase I
chr2_+_181845843 35.69 ENST00000602710.1
ubiquitin-conjugating enzyme E2E 3
chr8_-_101963482 34.90 ENST00000419477.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_-_185542817 34.70 ENST00000382199.2
insulin-like growth factor 2 mRNA binding protein 2
chr11_-_14380664 34.58 ENST00000545643.1
ENST00000256196.4
related RAS viral (r-ras) oncogene homolog 2
chr11_+_118272328 34.51 ENST00000524422.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr7_+_26240776 34.26 ENST00000337620.4
chromobox homolog 3
chr1_+_203830703 33.49 ENST00000414487.2
small nuclear ribonucleoprotein polypeptide E
chr14_+_51706886 33.34 ENST00000457354.2
thioredoxin-related transmembrane protein 1
chr5_+_159848807 33.00 ENST00000352433.5
pituitary tumor-transforming 1
chr9_-_179018 32.92 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
COBW domain containing 1
chr8_+_91013676 32.74 ENST00000519410.1
ENST00000522161.1
ENST00000517761.1
ENST00000520227.1
2,4-dienoyl CoA reductase 1, mitochondrial
chr6_+_52535878 32.47 ENST00000211314.4
transmembrane protein 14A
chr15_-_72523454 32.26 ENST00000565154.1
ENST00000565184.1
ENST00000389093.3
ENST00000449901.2
ENST00000335181.5
ENST00000319622.6
pyruvate kinase, muscle
chr20_-_60718430 32.00 ENST00000370873.4
ENST00000370858.3
proteasome (prosome, macropain) subunit, alpha type, 7
chr2_+_181845298 31.72 ENST00000410062.4
ubiquitin-conjugating enzyme E2E 3
chr8_-_81083341 31.63 ENST00000519303.2
tumor protein D52
chr1_+_155178481 31.60 ENST00000368376.3
metaxin 1
chr1_-_43638168 31.26 ENST00000431635.2
EBNA1 binding protein 2
chr15_-_66649010 31.15 ENST00000367709.4
ENST00000261881.4
TIMELESS interacting protein
chr7_-_140714739 31.13 ENST00000467334.1
ENST00000324787.5
mitochondrial ribosomal protein S33
chr3_+_52740094 30.32 ENST00000602728.1
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr2_-_69664549 30.32 ENST00000450796.2
ENST00000484177.1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr12_+_104609550 30.27 ENST00000525566.1
ENST00000429002.2
thioredoxin reductase 1
chr5_+_159848854 30.24 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr2_+_113403434 30.23 ENST00000272542.3
solute carrier family 20 (phosphate transporter), member 1
chr15_-_55489097 30.10 ENST00000260443.4
ribosomal L24 domain containing 1
chr16_-_85833160 29.96 ENST00000435200.2
ER membrane protein complex subunit 8
chr17_+_73257742 29.84 ENST00000579761.1
ENST00000245539.6
mitochondrial ribosomal protein S7
chr7_-_96339132 29.67 ENST00000413065.1
split hand/foot malformation (ectrodactyly) type 1
chr5_+_32585605 28.51 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1 homolog (S. cerevisiae)
chr12_-_50419177 28.50 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
Rac GTPase activating protein 1
chr7_+_16685756 28.34 ENST00000415365.1
ENST00000258761.3
ENST00000433922.2
ENST00000452975.2
ENST00000405202.1
basic leucine zipper and W2 domains 2
chr2_+_201171372 28.18 ENST00000409140.3
spermatogenesis associated, serine-rich 2-like
chr8_-_48872686 28.01 ENST00000314191.2
ENST00000338368.3
protein kinase, DNA-activated, catalytic polypeptide
chr14_-_68141535 27.76 ENST00000554659.1
vesicle transport through interaction with t-SNAREs 1B
chrX_-_153285395 27.73 ENST00000369980.3
interleukin-1 receptor-associated kinase 1
chr5_+_177631523 27.70 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
heterogeneous nuclear ribonucleoprotein A/B
chr1_-_54411240 27.59 ENST00000371378.2
heat shock protein family B (small), member 11
chr19_+_33071974 27.47 ENST00000590247.2
ENST00000419343.3
ENST00000592786.1
ENST00000379316.3
programmed cell death 5
chr5_+_1801503 27.46 ENST00000274137.5
ENST00000469176.1
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr13_+_28194873 27.32 ENST00000302979.3
polymerase (RNA) I polypeptide D, 16kDa
chr10_-_17659234 27.26 ENST00000466335.1
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr14_-_104029013 27.09 ENST00000299204.4
ENST00000557666.1
BCL2-associated athanogene 5
chr9_-_70490107 26.99 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
COBW domain containing 5
chr7_-_140714430 26.88 ENST00000393008.3
mitochondrial ribosomal protein S33
chr9_+_100745615 26.73 ENST00000339399.4
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr19_-_14628645 26.64 ENST00000598235.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr9_-_111775772 26.46 ENST00000325580.6
ENST00000374593.4
ENST00000374595.4
ENST00000325551.4
catenin (cadherin-associated protein), alpha-like 1
chr2_-_10587897 26.32 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr10_+_124913930 26.31 ENST00000368858.5
BUB3 mitotic checkpoint protein
chr5_-_68665469 26.21 ENST00000217893.5
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr6_+_36562132 26.19 ENST00000373715.6
ENST00000339436.7
serine/arginine-rich splicing factor 3
chr3_-_185542761 26.05 ENST00000457616.2
ENST00000346192.3
insulin-like growth factor 2 mRNA binding protein 2
chr19_-_6415695 25.70 ENST00000594496.1
ENST00000594745.1
ENST00000600480.1
KH-type splicing regulatory protein
chr3_-_134093275 25.67 ENST00000513145.1
ENST00000422605.2
angiomotin like 2
chr2_+_237994519 25.65 ENST00000392008.2
ENST00000409334.1
ENST00000409629.1
COP9 signalosome subunit 8
chr13_-_22178284 25.40 ENST00000468222.2
ENST00000382374.4
mitochondrial calcium uptake 2
chr7_-_86849025 25.33 ENST00000257637.3
transmembrane protein 243, mitochondrial
chr5_-_68665084 24.71 ENST00000509462.1
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr5_+_5422778 24.63 ENST00000296564.7
KIAA0947
chr12_+_93861264 24.46 ENST00000549982.1
ENST00000361630.2
mitochondrial ribosomal protein L42
chr1_-_43637915 24.43 ENST00000236051.2
EBNA1 binding protein 2
chr12_+_93861282 24.27 ENST00000552217.1
ENST00000393128.4
ENST00000547098.1
mitochondrial ribosomal protein L42
chr14_+_97263641 24.26 ENST00000216639.3
vaccinia related kinase 1
chr7_+_141438118 24.15 ENST00000265304.6
ENST00000498107.1
ENST00000467681.1
ENST00000465582.1
ENST00000463093.1
single-stranded DNA binding protein 1, mitochondrial
chr10_+_95256356 24.04 ENST00000371485.3
centrosomal protein 55kDa
chr5_-_68665815 23.93 ENST00000380818.3
ENST00000328663.4
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr20_-_54967187 23.79 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
aurora kinase A
chr2_+_200820269 23.78 ENST00000392290.1
chromosome 2 open reading frame 47
chr2_-_170681324 23.73 ENST00000409340.1
methyltransferase like 5
chr14_+_20937538 23.67 ENST00000361505.5
ENST00000553591.1
purine nucleoside phosphorylase
chr15_+_48623600 23.51 ENST00000558813.1
ENST00000331200.3
ENST00000558472.1
deoxyuridine triphosphatase
chr14_-_102553371 23.39 ENST00000553585.1
ENST00000216281.8
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr1_-_54411255 23.37 ENST00000371377.3
heat shock protein family B (small), member 11
chr2_-_69664586 23.30 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr1_+_948803 23.23 ENST00000379389.4
ISG15 ubiquitin-like modifier
chr15_-_101835414 23.10 ENST00000254193.6
small nuclear ribonucleoprotein polypeptide A'
chr1_+_155178518 22.96 ENST00000316721.4
metaxin 1
chr4_-_100871506 22.84 ENST00000296417.5
H2A histone family, member Z
chr20_+_47662805 22.72 ENST00000262982.2
ENST00000542325.1
CSE1 chromosome segregation 1-like (yeast)
chr4_-_170679024 22.72 ENST00000393381.2
chromosome 4 open reading frame 27
chr15_-_101835110 22.69 ENST00000560496.1
small nuclear ribonucleoprotein polypeptide A'
chr11_+_105948216 22.51 ENST00000278618.4
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr20_-_31989307 22.45 ENST00000473997.1
ENST00000544843.1
ENST00000346416.2
ENST00000357886.4
ENST00000339269.5
CDK5 regulatory subunit associated protein 1
chr18_+_657733 22.19 ENST00000323250.5
ENST00000323224.7
thymidylate synthetase
chr4_-_1714037 22.10 ENST00000488267.1
ENST00000429429.2
ENST00000480936.1
stem-loop binding protein
chr2_+_48010312 22.10 ENST00000540021.1
mutS homolog 6
chr2_+_181845074 22.09 ENST00000602959.1
ENST00000602479.1
ENST00000392415.2
ENST00000602291.1
ubiquitin-conjugating enzyme E2E 3
chr2_+_264869 22.03 ENST00000272067.6
ENST00000272065.5
ENST00000407983.3
acid phosphatase 1, soluble
chr9_+_127624387 22.02 ENST00000353214.2
actin related protein 2/3 complex, subunit 5-like
chr11_+_18416103 21.84 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
lactate dehydrogenase A
chr15_+_77224045 21.84 ENST00000320963.5
ENST00000394883.3
reticulocalbin 2, EF-hand calcium binding domain
chr9_+_70856899 21.79 ENST00000377342.5
ENST00000478048.1
COBW domain containing 3
chr7_+_12727250 21.78 ENST00000404894.1
ADP-ribosylation factor-like 4A
chr4_-_185655278 21.73 ENST00000281453.5
centromere protein U
chr17_-_47785265 21.68 ENST00000511763.1
ENST00000515850.1
ENST00000415270.2
ENST00000240333.6
solute carrier family 35, member B1
chr15_-_85259294 21.67 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11 homolog A (S. cerevisiae)
chr6_-_5261141 21.62 ENST00000330636.4
ENST00000500576.2
LYR motif containing 4
chr4_-_1713977 21.57 ENST00000318386.4
stem-loop binding protein
chr19_-_48894762 21.57 ENST00000600980.1
ENST00000330720.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr1_-_211752073 21.56 ENST00000367001.4
solute carrier family 30 (zinc transporter), member 1
chr8_+_91013577 21.54 ENST00000220764.2
2,4-dienoyl CoA reductase 1, mitochondrial
chr1_+_8021713 21.49 ENST00000338639.5
ENST00000493678.1
ENST00000377493.5
parkinson protein 7
chr3_-_134093395 21.46 ENST00000249883.5
angiomotin like 2
chr4_-_2965052 21.41 ENST00000398071.4
ENST00000502735.1
ENST00000314262.6
ENST00000416614.2
NOP14 nucleolar protein
chr1_+_44440575 21.31 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr12_-_112856623 21.31 ENST00000551291.2
ribosomal protein L6
chr1_+_87170577 21.29 ENST00000482504.1
SH3-domain GRB2-like endophilin B1
chr21_-_40555393 21.28 ENST00000380900.2
proteasome (prosome, macropain) assembly chaperone 1
chr3_+_172468472 21.28 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr12_-_15942503 21.22 ENST00000281172.5
epidermal growth factor receptor pathway substrate 8
chr11_+_102217936 21.15 ENST00000532832.1
ENST00000530675.1
ENST00000533742.1
ENST00000227758.2
ENST00000532672.1
ENST00000531259.1
ENST00000527465.1
baculoviral IAP repeat containing 2
chr8_+_26149007 21.11 ENST00000380737.3
ENST00000524169.1
protein phosphatase 2, regulatory subunit B, alpha
chr14_+_58711539 20.88 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr22_-_29949634 20.84 ENST00000397872.1
ENST00000397871.1
ENST00000440771.1
THO complex 5
chr13_+_76123883 20.81 ENST00000377595.3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr9_-_69262509 20.74 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
COBW domain containing 6
chr7_-_16685422 20.67 ENST00000306999.2
ankyrin repeat and MYND domain containing 2
chr15_+_59397275 20.64 ENST00000288207.2
cyclin B2
chr2_-_47168850 20.63 ENST00000409207.1
multiple coagulation factor deficiency 2
chr10_+_43278217 20.63 ENST00000374518.5
BMS1 ribosome biogenesis factor
chr4_-_120988229 20.62 ENST00000296509.6
MAD2 mitotic arrest deficient-like 1 (yeast)
chr2_+_114195268 20.62 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
COBW domain containing 2
chr6_-_79787902 20.52 ENST00000275034.4
pleckstrin homology domain interacting protein
chr12_+_133264635 20.49 ENST00000545677.1
ENST00000537262.1
peroxisomal membrane protein 2, 22kDa
Uncharacterized protein
chr5_+_10250328 20.45 ENST00000515390.1
chaperonin containing TCP1, subunit 5 (epsilon)
chr19_-_23941639 20.39 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
zinc finger protein 681
chr1_-_32801825 20.39 ENST00000329421.7
MARCKS-like 1
chr5_-_143550159 20.34 ENST00000448443.2
ENST00000513112.1
ENST00000519064.1
ENST00000274496.5
Yip1 domain family, member 5
chr3_+_139063372 20.24 ENST00000478464.1
mitochondrial ribosomal protein S22
chr14_+_54863739 20.06 ENST00000541304.1
cyclin-dependent kinase inhibitor 3
chrX_-_153718953 20.06 ENST00000369649.4
ENST00000393586.1
solute carrier family 10, member 3
chr6_+_10748019 20.05 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
synaptonemal complex protein 2-like
transmembrane protein 14B
chr5_+_112196919 20.04 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
signal recognition particle 19kDa
chr9_-_95055956 19.99 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
isoleucyl-tRNA synthetase
chrX_-_153707246 19.84 ENST00000407062.1
L antigen family, member 3
chr15_-_72523924 19.70 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
pyruvate kinase, muscle
chr18_-_47018897 19.67 ENST00000418495.1
ribosomal protein L17
chr1_+_90287480 19.45 ENST00000394593.3
leucine rich repeat containing 8 family, member D
chr15_+_59397298 19.45 ENST00000559622.1
cyclin B2
chr7_-_64023441 19.44 ENST00000309683.6
zinc finger protein 680
chr1_+_161719552 19.43 ENST00000367943.4
dual specificity phosphatase 12
chr7_+_98923505 19.43 ENST00000432884.2
ENST00000262942.5
actin related protein 2/3 complex, subunit 1A, 41kDa
chr7_+_73097890 19.37 ENST00000265758.2
ENST00000423166.2
ENST00000423497.1
Williams Beuren syndrome chromosome region 22
chr1_+_155658849 19.34 ENST00000368336.5
ENST00000343043.3
ENST00000421487.2
ENST00000535183.1
ENST00000465375.1
ENST00000470830.1
death associated protein 3
chr14_-_104028595 19.29 ENST00000337322.4
ENST00000445922.2
BCL2-associated athanogene 5
chr19_+_49497121 19.27 ENST00000413176.2
RuvB-like AAA ATPase 2
chr15_-_85259330 19.21 ENST00000560266.1
SEC11 homolog A (S. cerevisiae)
chr11_+_70049269 19.12 ENST00000301838.4
Fas (TNFRSF6)-associated via death domain
chr19_-_10530784 19.04 ENST00000593124.1
cell division cycle 37
chr1_+_161284047 19.00 ENST00000367975.2
ENST00000342751.4
ENST00000432287.2
ENST00000392169.2
ENST00000513009.1
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
chr8_-_80942139 19.00 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
mitochondrial ribosomal protein S28
chr4_+_17812525 18.99 ENST00000251496.2
non-SMC condensin I complex, subunit G
chr10_+_124913793 18.97 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3 mitotic checkpoint protein
chr5_+_34915444 18.91 ENST00000336767.5
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr12_+_57623869 18.89 ENST00000414700.3
ENST00000557703.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr14_+_54863682 18.79 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
cyclin-dependent kinase inhibitor 3
chr15_+_66797455 18.79 ENST00000446801.2
zwilch kinetochore protein
chr20_-_57617831 18.77 ENST00000371033.5
ENST00000355937.4
slowmo homolog 2 (Drosophila)
chr1_-_8938736 18.57 ENST00000234590.4
enolase 1, (alpha)
chr18_+_20513278 18.53 ENST00000327155.5
retinoblastoma binding protein 8
chr17_+_1944790 18.51 ENST00000575162.1
diphthamide biosynthesis 1
chr18_-_47018769 18.51 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chr2_-_207024134 18.49 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_-_42588338 18.27 ENST00000234301.2
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr1_+_166808692 18.25 ENST00000367876.4
pogo transposable element with KRAB domain
chr2_-_84686552 18.15 ENST00000393868.2
succinate-CoA ligase, alpha subunit
chr15_+_48623208 18.14 ENST00000559935.1
ENST00000559416.1
deoxyuridine triphosphatase
chr3_+_158519654 18.09 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
major facilitator superfamily domain containing 1
chr9_+_116037922 18.08 ENST00000374198.4
pre-mRNA processing factor 4
chr2_-_170430277 18.05 ENST00000438035.1
ENST00000453929.2
FAST kinase domains 1
chr3_+_151986709 18.02 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
muscleblind-like splicing regulator 1
chr19_-_1095330 17.91 ENST00000586746.1
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr5_-_79950371 17.89 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
dihydrofolate reductase
chrX_-_153718988 17.81 ENST00000263512.4
ENST00000393587.4
ENST00000453912.1
solute carrier family 10, member 3
chr11_-_34938039 17.80 ENST00000395787.3
APAF1 interacting protein
chr7_-_138794081 17.77 ENST00000464606.1
zinc finger CCCH-type, antiviral 1
chr14_-_50154921 17.76 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
polymerase (DNA directed), epsilon 2, accessory subunit
chr1_-_63988846 17.74 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
integrin beta 3 binding protein (beta3-endonexin)
chr8_-_63951730 17.69 ENST00000260118.6
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr20_+_52824367 17.59 ENST00000371419.2
prefoldin subunit 4
chr2_-_174828892 17.52 ENST00000418194.2
Sp3 transcription factor
chr20_+_23331373 17.49 ENST00000254998.2
NTF2-like export factor 1
chr14_-_102552659 17.49 ENST00000441629.2
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr7_-_87849340 17.42 ENST00000419179.1
ENST00000265729.2
sorcin
chr1_-_246729544 17.41 ENST00000544618.1
ENST00000366514.4
transcription factor B2, mitochondrial
chr1_+_54411715 17.40 ENST00000371370.3
ENST00000371368.1
leucine rich repeat containing 42
chr3_-_63849571 17.37 ENST00000295899.5
THO complex 7 homolog (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
15.1 45.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
13.9 83.5 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
13.9 41.6 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
12.6 37.7 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
12.1 36.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
11.6 150.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
11.2 44.6 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
11.1 55.3 GO:0009438 methylglyoxal metabolic process(GO:0009438)
10.8 32.5 GO:0044209 AMP salvage(GO:0044209)
10.2 40.9 GO:0043335 protein unfolding(GO:0043335)
10.0 29.9 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
9.3 37.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
9.2 73.9 GO:1903333 negative regulation of protein folding(GO:1903333)
9.0 45.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
8.8 26.3 GO:0006738 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
8.7 43.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
8.7 52.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
8.4 33.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
8.2 32.8 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
8.1 24.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
8.1 32.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
7.9 23.8 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
7.7 31.0 GO:0009202 dTTP biosynthetic process(GO:0006235) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
7.7 23.2 GO:0007113 endomitotic cell cycle(GO:0007113)
7.7 23.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
7.5 44.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
7.4 29.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
7.2 21.7 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
7.2 35.8 GO:0061198 fungiform papilla formation(GO:0061198)
7.1 21.4 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
7.1 21.2 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
7.0 7.0 GO:0048254 snoRNA localization(GO:0048254)
6.9 48.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
6.8 34.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
6.7 20.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
6.6 26.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
6.4 32.0 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
6.3 19.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
6.3 19.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
6.3 37.6 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
6.3 6.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
6.2 31.1 GO:0048478 replication fork protection(GO:0048478)
6.1 24.3 GO:0090166 Golgi disassembly(GO:0090166)
5.9 17.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
5.8 28.8 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
5.7 17.2 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
5.6 16.8 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
5.6 16.7 GO:0006097 glyoxylate cycle(GO:0006097)
5.5 44.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
5.4 16.3 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
5.4 27.0 GO:0097501 stress response to metal ion(GO:0097501)
5.3 16.0 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
5.3 37.1 GO:0000710 meiotic mismatch repair(GO:0000710)
5.2 15.6 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
5.1 15.4 GO:1901873 regulation of post-translational protein modification(GO:1901873)
5.1 35.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
5.0 372.5 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
5.0 15.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
5.0 14.9 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
4.9 39.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
4.9 34.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
4.8 19.1 GO:0072683 T cell extravasation(GO:0072683)
4.7 18.9 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
4.7 42.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
4.6 41.7 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
4.6 101.5 GO:0006465 signal peptide processing(GO:0006465)
4.6 13.7 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
4.5 9.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
4.5 8.9 GO:0042256 mature ribosome assembly(GO:0042256)
4.4 48.7 GO:0090168 Golgi reassembly(GO:0090168)
4.4 13.1 GO:0051685 maintenance of ER location(GO:0051685)
4.4 17.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
4.3 12.8 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
4.2 37.6 GO:0001887 selenium compound metabolic process(GO:0001887)
4.1 20.7 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
4.1 49.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
4.0 12.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
4.0 100.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
4.0 24.0 GO:0031126 snoRNA 3'-end processing(GO:0031126)
4.0 12.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
4.0 15.8 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
3.9 15.4 GO:2000819 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) regulation of nucleotide-excision repair(GO:2000819)
3.8 49.8 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
3.8 22.9 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
3.8 11.5 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
3.8 11.3 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.8 30.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
3.8 22.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
3.8 49.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
3.7 29.8 GO:0015866 ADP transport(GO:0015866)
3.7 11.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
3.7 26.0 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
3.7 14.8 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
3.7 11.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
3.7 25.7 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
3.7 22.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
3.6 21.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
3.6 46.7 GO:0070986 left/right axis specification(GO:0070986)
3.6 10.7 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
3.5 14.2 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
3.5 10.5 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
3.5 13.9 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
3.4 37.9 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
3.4 34.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
3.3 16.7 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
3.3 19.9 GO:0006177 GMP biosynthetic process(GO:0006177)
3.3 22.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
3.3 9.8 GO:0006788 heme oxidation(GO:0006788)
3.2 19.4 GO:0006021 inositol biosynthetic process(GO:0006021)
3.2 22.5 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
3.2 9.6 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
3.2 51.3 GO:0043248 proteasome assembly(GO:0043248)
3.2 9.6 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
3.2 9.6 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
3.2 70.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
3.1 25.2 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
3.1 18.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
3.1 31.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
3.1 6.2 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
3.1 9.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
3.1 46.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
3.1 21.5 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
3.1 15.4 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
3.0 24.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
3.0 36.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
3.0 88.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
3.0 12.1 GO:0006642 triglyceride mobilization(GO:0006642)
3.0 12.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
3.0 8.9 GO:0006740 NADPH regeneration(GO:0006740)
3.0 41.3 GO:0000022 mitotic spindle elongation(GO:0000022)
2.9 5.9 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
2.9 17.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
2.9 23.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.9 17.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
2.9 92.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
2.8 11.3 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
2.8 187.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
2.8 2.8 GO:0030888 regulation of B cell proliferation(GO:0030888)
2.8 30.4 GO:0006089 lactate metabolic process(GO:0006089)
2.7 13.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
2.7 13.6 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.7 13.6 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
2.7 10.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
2.7 13.4 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
2.7 8.0 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
2.7 16.0 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
2.7 26.6 GO:0042407 cristae formation(GO:0042407)
2.7 8.0 GO:1901297 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
2.7 13.3 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
2.7 18.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
2.7 8.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
2.6 303.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
2.6 23.4 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
2.6 10.3 GO:0002317 plasma cell differentiation(GO:0002317)
2.6 23.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.6 17.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
2.5 12.7 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
2.5 10.2 GO:0044375 regulation of peroxisome size(GO:0044375)
2.5 7.6 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
2.5 30.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
2.5 7.5 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
2.5 10.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
2.5 17.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.5 56.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
2.5 2.5 GO:0009441 glycolate metabolic process(GO:0009441)
2.5 9.8 GO:1903826 arginine transmembrane transport(GO:1903826)
2.5 44.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
2.4 7.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
2.4 9.6 GO:0090309 maintenance of DNA methylation(GO:0010216) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
2.4 14.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
2.4 4.7 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
2.4 11.8 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
2.3 28.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
2.3 9.3 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
2.3 6.9 GO:0016074 snoRNA metabolic process(GO:0016074)
2.3 9.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
2.3 11.4 GO:0030047 actin modification(GO:0030047)
2.3 6.8 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
2.3 106.8 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
2.3 15.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
2.3 2.3 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
2.3 4.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
2.3 13.5 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
2.3 22.5 GO:0015939 pantothenate metabolic process(GO:0015939)
2.2 18.0 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
2.2 11.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
2.2 11.1 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
2.2 17.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
2.2 6.6 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
2.2 6.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
2.2 35.0 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
2.2 13.0 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
2.1 115.8 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
2.1 10.7 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
2.1 8.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
2.1 6.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
2.1 6.3 GO:0009726 detection of endogenous stimulus(GO:0009726)
2.1 2.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
2.1 8.2 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
2.1 8.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
2.1 10.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
2.0 6.1 GO:0070668 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
2.0 8.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.0 6.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
2.0 8.0 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
2.0 5.9 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
2.0 4.0 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
2.0 35.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
2.0 7.8 GO:0010815 bradykinin catabolic process(GO:0010815)
1.9 5.8 GO:0046294 formaldehyde catabolic process(GO:0046294)
1.9 42.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.9 9.6 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
1.9 5.7 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.9 11.5 GO:1904044 response to aldosterone(GO:1904044)
1.9 13.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
1.9 7.6 GO:0046108 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
1.9 9.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.9 24.4 GO:0045008 depyrimidination(GO:0045008)
1.9 7.5 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
1.8 1.8 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
1.8 12.9 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.8 5.5 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
1.8 20.2 GO:0051310 metaphase plate congression(GO:0051310)
1.8 14.6 GO:0042262 DNA protection(GO:0042262)
1.8 10.8 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
1.8 5.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
1.8 7.2 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
1.8 3.5 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
1.8 14.1 GO:0070200 establishment of protein localization to telomere(GO:0070200)
1.8 15.9 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
1.8 8.8 GO:0061738 late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.8 124.4 GO:0045454 cell redox homeostasis(GO:0045454)
1.7 8.7 GO:0019401 alditol biosynthetic process(GO:0019401)
1.7 17.2 GO:1900016 negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
1.7 17.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.7 8.5 GO:0009838 abscission(GO:0009838)
1.7 22.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.7 13.5 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
1.7 8.4 GO:0006529 asparagine biosynthetic process(GO:0006529)
1.7 8.4 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.7 6.7 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.6 13.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.6 13.2 GO:0010608 posttranscriptional regulation of gene expression(GO:0010608)
1.6 6.6 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
1.6 11.4 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
1.6 1.6 GO:0006273 lagging strand elongation(GO:0006273)
1.6 17.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.6 19.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.6 36.3 GO:0061157 mRNA destabilization(GO:0061157)
1.6 18.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
1.6 39.4 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
1.6 12.4 GO:0042182 ketone catabolic process(GO:0042182)
1.6 6.2 GO:0046967 cytosol to ER transport(GO:0046967)
1.5 4.6 GO:1904647 response to rotenone(GO:1904647)
1.5 27.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.5 13.7 GO:0090400 stress-induced premature senescence(GO:0090400)
1.5 7.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.5 12.0 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.5 11.8 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.5 2.9 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
1.5 1.5 GO:0021539 subthalamus development(GO:0021539)
1.4 7.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
1.4 10.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.4 64.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
1.4 14.4 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
1.4 7.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.4 5.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
1.4 5.6 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
1.4 7.0 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
1.4 15.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
1.4 57.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
1.4 15.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.4 4.1 GO:0006014 D-ribose metabolic process(GO:0006014)
1.3 25.6 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
1.3 153.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
1.3 10.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.3 5.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
1.3 9.2 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
1.3 6.5 GO:0060356 leucine import(GO:0060356)
1.3 34.6 GO:0006301 postreplication repair(GO:0006301)
1.3 3.8 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.3 7.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.3 5.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
1.3 3.8 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
1.3 6.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
1.2 13.7 GO:0033327 Leydig cell differentiation(GO:0033327)
1.2 9.9 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
1.2 3.6 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
1.2 14.5 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.2 3.6 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.2 21.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.2 19.1 GO:0035067 negative regulation of histone acetylation(GO:0035067)
1.2 22.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.1 9.2 GO:0002934 desmosome organization(GO:0002934)
1.1 4.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
1.1 10.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.1 5.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.1 12.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.1 34.2 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
1.1 3.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
1.1 13.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.1 38.3 GO:0050873 brown fat cell differentiation(GO:0050873)
1.1 3.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
1.1 21.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
1.1 10.7 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
1.1 10.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
1.1 9.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.1 5.3 GO:0075713 establishment of integrated proviral latency(GO:0075713)
1.0 11.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
1.0 9.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
1.0 4.2 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.0 21.8 GO:0008334 histone mRNA metabolic process(GO:0008334)
1.0 12.4 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
1.0 16.4 GO:2001205 negative regulation of osteoclast development(GO:2001205)
1.0 1.0 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of terminal mannose on C branch(GO:0036510) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
1.0 3.0 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.0 7.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.0 8.0 GO:2000210 positive regulation of anoikis(GO:2000210)
1.0 14.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
1.0 4.0 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
1.0 8.0 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.0 4.0 GO:0030242 pexophagy(GO:0030242)
1.0 1.0 GO:0040031 snRNA modification(GO:0040031)
1.0 3.0 GO:0044806 positive regulation of deoxyribonuclease activity(GO:0032077) positive regulation of endodeoxyribonuclease activity(GO:0032079) G-quadruplex DNA unwinding(GO:0044806)
1.0 8.9 GO:0040016 embryonic cleavage(GO:0040016)
1.0 40.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.0 2.9 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
1.0 11.7 GO:0007379 segment specification(GO:0007379)
1.0 10.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.9 20.6 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.9 2.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.9 8.3 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.9 6.3 GO:0030091 protein repair(GO:0030091)
0.9 8.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.9 3.6 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.9 1.8 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.9 4.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.9 7.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.9 2.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.9 2.6 GO:0043318 regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318) insulin catabolic process(GO:1901143)
0.9 3.4 GO:0032506 cytokinetic process(GO:0032506)
0.9 4.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.9 2.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.9 22.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.8 18.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.8 1.7 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.8 2.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.8 6.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.8 6.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.8 7.5 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.8 18.4 GO:0006825 copper ion transport(GO:0006825)
0.8 4.2 GO:0035811 negative regulation of urine volume(GO:0035811)
0.8 6.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.8 14.3 GO:0043486 histone exchange(GO:0043486)
0.8 31.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.8 9.5 GO:0050872 white fat cell differentiation(GO:0050872)
0.8 3.9 GO:0007386 compartment pattern specification(GO:0007386)
0.8 6.3 GO:0002021 response to dietary excess(GO:0002021)
0.8 32.5 GO:0090307 mitotic spindle assembly(GO:0090307)
0.8 6.9 GO:0048745 smooth muscle tissue development(GO:0048745)
0.8 7.7 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.8 2.3 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.8 2.3 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.8 48.8 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.8 2.3 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.7 15.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.7 14.7 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.7 9.5 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.7 50.4 GO:0051289 protein homotetramerization(GO:0051289)
0.7 58.4 GO:0007062 sister chromatid cohesion(GO:0007062)
0.7 17.9 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.7 10.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.7 3.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.7 2.1 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.7 11.6 GO:0022904 respiratory electron transport chain(GO:0022904)
0.7 2.7 GO:0060434 bronchus morphogenesis(GO:0060434)
0.7 6.7 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.7 2.7 GO:0034612 response to tumor necrosis factor(GO:0034612)
0.7 4.0 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.7 3.3 GO:0031337 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.7 2.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.7 2.0 GO:0036302 atrioventricular canal development(GO:0036302)
0.6 4.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.6 1.3 GO:0010041 response to iron(III) ion(GO:0010041)
0.6 13.4 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.6 7.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.6 8.2 GO:0006289 nucleotide-excision repair(GO:0006289)
0.6 3.8 GO:0030421 defecation(GO:0030421)
0.6 2.5 GO:0060283 negative regulation of oocyte development(GO:0060283) regulation of oocyte maturation(GO:1900193) negative regulation of oocyte maturation(GO:1900194)
0.6 13.6 GO:0016578 histone deubiquitination(GO:0016578)
0.6 8.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.6 2.4 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.6 4.2 GO:0006983 ER overload response(GO:0006983)
0.6 35.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.6 6.6 GO:0072697 protein localization to cell cortex(GO:0072697) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.6 1.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.6 16.7 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.6 1.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.6 6.5 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.6 6.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.6 9.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.6 2.3 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.6 23.9 GO:0035329 hippo signaling(GO:0035329)
0.6 3.4 GO:0061042 vascular wound healing(GO:0061042)
0.6 10.8 GO:0035456 response to interferon-beta(GO:0035456)
0.6 23.7 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.6 3.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.5 4.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.5 1.6 GO:0033341 regulation of collagen binding(GO:0033341)
0.5 3.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.5 15.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.5 13.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.5 3.7 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.5 2.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.5 11.0 GO:0070207 protein homotrimerization(GO:0070207)
0.5 3.7 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.5 4.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.5 2.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.5 1.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.5 6.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.5 1.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.5 8.0 GO:0018345 protein palmitoylation(GO:0018345)
0.5 11.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.5 35.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.5 4.9 GO:0015889 cobalamin transport(GO:0015889)
0.5 3.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.5 2.3 GO:0071895 odontoblast differentiation(GO:0071895)
0.5 3.7 GO:0051132 NK T cell activation(GO:0051132)
0.5 6.0 GO:0006379 mRNA cleavage(GO:0006379)
0.5 43.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.5 1.8 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.5 8.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.5 2.7 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.5 9.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.5 3.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.4 15.3 GO:0043114 regulation of vascular permeability(GO:0043114)
0.4 6.3 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.4 0.9 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 2.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.4 6.8 GO:0002003 angiotensin maturation(GO:0002003)
0.4 7.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.4 9.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.4 2.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.4 2.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.4 5.3 GO:0006012 galactose metabolic process(GO:0006012)
0.4 1.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 3.6 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.4 2.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 43.4 GO:0070268 cornification(GO:0070268)
0.4 2.3 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.4 1.6 GO:0071233 cellular response to leucine(GO:0071233)
0.4 5.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.4 10.7 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.4 3.0 GO:0030252 growth hormone secretion(GO:0030252)
0.4 0.8 GO:0061511 centriole elongation(GO:0061511)
0.4 1.1 GO:0060373 glycerol-3-phosphate metabolic process(GO:0006072) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.4 1.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.4 8.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.4 15.0 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.4 1.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.4 3.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.4 1.4 GO:0007296 vitellogenesis(GO:0007296)
0.4 3.5 GO:0033197 response to vitamin E(GO:0033197)
0.4 5.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.3 5.5 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.3 4.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 13.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 16.3 GO:0070988 demethylation(GO:0070988)
0.3 1.3 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 3.9 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3 29.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.3 1.6 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.3 8.6 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.3 2.8 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.3 0.8 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.3 7.5 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.3 1.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.3 1.4 GO:1990791 renal artery morphogenesis(GO:0061441) dorsal root ganglion development(GO:1990791)
0.3 67.7 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.3 1.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 3.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 4.5 GO:0016925 protein sumoylation(GO:0016925)
0.3 1.0 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.3 2.9 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.3 4.9 GO:0002643 regulation of tolerance induction(GO:0002643)
0.3 0.8 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.3 13.4 GO:0045333 cellular respiration(GO:0045333)
0.2 4.9 GO:0014823 response to activity(GO:0014823)
0.2 3.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 5.7 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2 2.8 GO:0031424 keratinization(GO:0031424)
0.2 0.9 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 1.4 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.2 5.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 4.1 GO:0019054 modulation by virus of host process(GO:0019054)
0.2 4.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 0.9 GO:0050957 equilibrioception(GO:0050957)
0.2 1.8 GO:0015816 glycine transport(GO:0015816)
0.2 1.1 GO:1901018 positive regulation of potassium ion transmembrane transporter activity(GO:1901018)
0.2 4.6 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.2 1.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.2 2.5 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.2 1.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 1.1 GO:0007035 vacuolar acidification(GO:0007035)
0.2 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 5.9 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 5.7 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.2 2.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 2.5 GO:0030011 maintenance of cell polarity(GO:0030011)
0.2 5.2 GO:0001755 neural crest cell migration(GO:0001755)
0.2 5.0 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.2 1.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 3.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.4 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.4 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.5 GO:0030510 regulation of BMP signaling pathway(GO:0030510)
0.1 8.2 GO:0006901 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 6.9 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 4.8 GO:0001895 retina homeostasis(GO:0001895)
0.1 0.5 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 1.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.3 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.4 GO:0002739 regulation of cytokine secretion involved in immune response(GO:0002739) positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.1 10.8 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.1 3.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 4.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 2.9 GO:0001960 negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.1 8.5 GO:0006413 translational initiation(GO:0006413)
0.1 0.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 1.1 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715)
0.1 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 5.7 GO:0006968 cellular defense response(GO:0006968)
0.1 0.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.4 GO:0048286 lung alveolus development(GO:0048286)
0.1 0.4 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 2.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 2.1 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 0.5 GO:0014041 regulation of neuron maturation(GO:0014041)
0.1 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 0.3 GO:0019827 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.1 1.0 GO:0007409 axonogenesis(GO:0007409)
0.1 2.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 1.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 4.7 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.9 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.1 1.1 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1 1.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.1 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.2 GO:0006554 lysine catabolic process(GO:0006554)
0.0 0.3 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.7 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.6 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0097502 mannosylation(GO:0097502)
0.0 1.2 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 1.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
16.4 82.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
15.1 45.3 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
14.5 101.5 GO:0005787 signal peptidase complex(GO:0005787)
13.4 106.9 GO:0070761 pre-snoRNP complex(GO:0070761)
13.2 65.9 GO:0097149 centralspindlin complex(GO:0097149)
11.3 11.3 GO:0031261 DNA replication preinitiation complex(GO:0031261)
11.0 44.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
10.9 43.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
10.6 42.4 GO:0000811 GINS complex(GO:0000811)
10.5 282.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
8.8 44.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
8.5 34.1 GO:1990423 RZZ complex(GO:1990423)
7.8 39.0 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
7.7 30.6 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
7.3 29.4 GO:0071001 U4/U6 snRNP(GO:0071001)
7.3 73.2 GO:0070938 contractile ring(GO:0070938)
7.1 21.4 GO:0030689 Noc complex(GO:0030689)
7.1 85.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
7.1 35.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
7.0 28.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
7.0 7.0 GO:0005687 U4 snRNP(GO:0005687)
6.5 39.2 GO:0071817 MMXD complex(GO:0071817)
5.9 52.7 GO:0072546 ER membrane protein complex(GO:0072546)
5.7 22.9 GO:0031417 NatC complex(GO:0031417)
5.6 33.5 GO:0005683 U7 snRNP(GO:0005683)
5.5 22.1 GO:0032301 MutSalpha complex(GO:0032301)
5.5 16.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942) Ndc80 complex(GO:0031262)
5.5 43.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
5.4 43.4 GO:0097255 R2TP complex(GO:0097255)
5.4 21.7 GO:1990246 uniplex complex(GO:1990246)
5.2 31.1 GO:0031298 replication fork protection complex(GO:0031298)
5.0 30.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
4.8 14.4 GO:0043159 acrosomal matrix(GO:0043159)
4.7 37.7 GO:1990111 spermatoproteasome complex(GO:1990111)
4.7 28.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
4.6 37.2 GO:0070552 BRISC complex(GO:0070552)
4.6 32.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
4.5 13.6 GO:0005960 glycine cleavage complex(GO:0005960)
4.5 13.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
4.4 17.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
4.4 21.9 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
4.3 17.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
4.2 75.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
4.1 20.7 GO:0043564 Ku70:Ku80 complex(GO:0043564)
4.0 63.4 GO:0031080 nuclear pore outer ring(GO:0031080)
3.9 11.7 GO:0097447 dendritic tree(GO:0097447)
3.8 22.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
3.7 22.3 GO:0001740 Barr body(GO:0001740)
3.6 65.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
3.5 20.9 GO:0072589 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
3.4 10.3 GO:0034680 integrin alpha1-beta1 complex(GO:0034665) integrin alpha3-beta1 complex(GO:0034667) integrin alpha8-beta1 complex(GO:0034678) integrin alpha10-beta1 complex(GO:0034680)
3.4 37.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
3.4 6.7 GO:0070939 Dsl1p complex(GO:0070939)
3.3 3.3 GO:1902636 kinociliary basal body(GO:1902636)
3.2 32.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
3.2 19.3 GO:0070545 PeBoW complex(GO:0070545)
3.1 22.0 GO:1990635 proximal dendrite(GO:1990635)
3.1 12.5 GO:0005828 kinetochore microtubule(GO:0005828)
3.1 9.3 GO:0018444 translation release factor complex(GO:0018444)
3.1 18.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
3.0 6.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
3.0 21.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
3.0 12.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
3.0 23.8 GO:0032133 chromosome passenger complex(GO:0032133)
2.9 41.1 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
2.9 29.3 GO:0000796 condensin complex(GO:0000796)
2.8 68.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
2.8 22.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.8 11.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
2.8 11.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
2.8 74.7 GO:0000178 exosome (RNase complex)(GO:0000178)
2.7 167.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
2.7 32.5 GO:0090543 Flemming body(GO:0090543)
2.7 45.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
2.6 34.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
2.6 18.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
2.6 10.6 GO:0033186 CAF-1 complex(GO:0033186)
2.6 21.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
2.5 15.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
2.5 48.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
2.5 35.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
2.5 47.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
2.5 12.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
2.5 17.6 GO:0016272 prefoldin complex(GO:0016272)
2.5 20.0 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
2.5 17.4 GO:0044326 dendritic spine neck(GO:0044326)
2.4 21.8 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
2.4 29.0 GO:0001741 XY body(GO:0001741)
2.4 26.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
2.4 26.1 GO:0005688 U6 snRNP(GO:0005688)
2.4 253.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
2.3 13.9 GO:0008537 proteasome activator complex(GO:0008537)
2.3 32.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
2.3 38.6 GO:0005686 U2 snRNP(GO:0005686)
2.2 15.6 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
2.2 15.5 GO:0061617 MICOS complex(GO:0061617)
2.2 28.8 GO:0042555 MCM complex(GO:0042555)
2.2 8.6 GO:0005839 proteasome core complex(GO:0005839)
2.2 30.2 GO:0005662 DNA replication factor A complex(GO:0005662)
2.1 32.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
2.1 100.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
2.1 17.0 GO:0031931 TORC1 complex(GO:0031931)
2.1 4.2 GO:0045259 proton-transporting ATP synthase complex(GO:0045259)
2.1 4.2 GO:0097454 Schwann cell microvillus(GO:0097454)
2.1 6.3 GO:0045180 basal cortex(GO:0045180)
2.0 6.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
2.0 83.8 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
2.0 34.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
2.0 10.1 GO:0031010 ISWI-type complex(GO:0031010)
2.0 7.9 GO:0070876 SOSS complex(GO:0070876)
2.0 35.5 GO:0097342 ripoptosome(GO:0097342)
1.9 39.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.9 9.3 GO:0035578 azurophil granule lumen(GO:0035578)
1.9 16.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.8 34.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
1.8 21.2 GO:0042405 nuclear inclusion body(GO:0042405)
1.7 33.0 GO:0030686 90S preribosome(GO:0030686)
1.7 5.2 GO:0097431 mitotic spindle pole(GO:0097431)
1.7 12.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.7 10.2 GO:0031088 platelet dense granule membrane(GO:0031088)
1.7 142.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
1.7 50.7 GO:0005680 anaphase-promoting complex(GO:0005680)
1.7 31.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.6 8.2 GO:0042643 actomyosin, actin portion(GO:0042643)
1.6 6.5 GO:0032044 DSIF complex(GO:0032044)
1.6 9.5 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
1.6 15.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
1.6 4.7 GO:0033565 ESCRT-0 complex(GO:0033565)
1.6 15.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.5 64.2 GO:0000502 proteasome complex(GO:0000502)
1.5 6.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.5 16.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
1.5 31.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.5 19.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
1.4 15.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.4 2.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
1.4 30.2 GO:0030992 intraciliary transport particle B(GO:0030992)
1.3 14.5 GO:0000124 SAGA complex(GO:0000124)
1.3 7.8 GO:0032311 angiogenin-PRI complex(GO:0032311)
1.3 5.2 GO:0043260 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
1.3 3.8 GO:0005726 perichromatin fibrils(GO:0005726)
1.3 33.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.3 8.8 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
1.3 6.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.2 34.1 GO:0070469 respiratory chain(GO:0070469)
1.2 9.3 GO:0051286 cell tip(GO:0051286)
1.2 4.6 GO:0055087 Ski complex(GO:0055087)
1.2 10.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.1 196.9 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
1.1 13.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.1 13.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.1 35.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.1 8.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.1 7.5 GO:0071203 WASH complex(GO:0071203)
1.0 12.5 GO:0000815 ESCRT III complex(GO:0000815)
1.0 6.2 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
1.0 8.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.0 1.0 GO:0000938 GARP complex(GO:0000938)
1.0 6.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.0 9.1 GO:0010369 chromocenter(GO:0010369)
1.0 3.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
1.0 11.9 GO:0001673 male germ cell nucleus(GO:0001673)
1.0 9.6 GO:0005721 pericentric heterochromatin(GO:0005721)
1.0 15.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.9 3.7 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.9 10.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.9 2.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.9 2.8 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.9 49.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.9 4.6 GO:0032389 MutLalpha complex(GO:0032389)
0.9 1.8 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.9 18.0 GO:0005801 cis-Golgi network(GO:0005801)
0.9 14.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.9 38.6 GO:0008180 COP9 signalosome(GO:0008180)
0.9 1.7 GO:0031089 platelet dense granule lumen(GO:0031089) platelet dense granule(GO:0042827)
0.8 4.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.8 6.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.8 8.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.8 4.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.8 2.4 GO:0031213 RSF complex(GO:0031213)
0.8 13.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.8 10.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.7 9.7 GO:0097470 ribbon synapse(GO:0097470)
0.7 14.0 GO:0005844 polysome(GO:0005844)
0.7 98.6 GO:0030496 midbody(GO:0030496)
0.7 13.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.7 7.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.7 20.2 GO:0030057 desmosome(GO:0030057)
0.7 4.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.7 1.3 GO:0071159 NF-kappaB complex(GO:0071159)
0.7 88.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.6 39.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.6 4.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.6 7.5 GO:0032433 filopodium tip(GO:0032433)
0.6 2.5 GO:0031673 H zone(GO:0031673)
0.6 4.9 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.6 6.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 5.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.6 1.8 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.6 17.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.6 37.5 GO:0005643 nuclear pore(GO:0005643)
0.6 7.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.6 7.3 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.6 3.9 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.6 6.1 GO:0005614 interstitial matrix(GO:0005614)
0.6 22.8 GO:0045095 keratin filament(GO:0045095)
0.6 197.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.5 14.7 GO:0035869 ciliary transition zone(GO:0035869)
0.5 22.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.5 33.2 GO:0045178 basal part of cell(GO:0045178)
0.5 10.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.5 20.3 GO:0002102 podosome(GO:0002102)
0.5 2.6 GO:0032449 CBM complex(GO:0032449)
0.5 26.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.5 1.9 GO:0070695 FHF complex(GO:0070695)
0.5 5.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.5 5.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.5 8.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.5 2.8 GO:0000242 pericentriolar material(GO:0000242)
0.4 40.3 GO:0005681 spliceosomal complex(GO:0005681)
0.4 7.2 GO:0036020 endolysosome membrane(GO:0036020)
0.4 24.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.4 2.3 GO:0071438 invadopodium membrane(GO:0071438)
0.4 6.8 GO:0030904 retromer complex(GO:0030904)
0.4 9.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 15.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 6.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.3 2.7 GO:0097546 ciliary base(GO:0097546)
0.3 14.7 GO:0001725 stress fiber(GO:0001725) actin filament bundle(GO:0032432) contractile actin filament bundle(GO:0097517)
0.3 4.8 GO:0005814 centriole(GO:0005814)
0.3 7.4 GO:0000776 kinetochore(GO:0000776)
0.3 1.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 4.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.3 3.8 GO:0031209 SCAR complex(GO:0031209)
0.3 17.7 GO:0005811 lipid particle(GO:0005811)
0.3 1.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.3 13.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 5.2 GO:0030125 clathrin vesicle coat(GO:0030125)
0.3 2.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.3 100.0 GO:0016607 nuclear speck(GO:0016607)
0.3 2.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 13.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 26.1 GO:0005923 bicellular tight junction(GO:0005923)
0.2 11.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 4.6 GO:1902494 catalytic complex(GO:1902494)
0.2 0.2 GO:0032302 MutSbeta complex(GO:0032302)
0.2 32.1 GO:0042383 sarcolemma(GO:0042383)
0.2 1.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 0.8 GO:0030914 STAGA complex(GO:0030914)
0.2 0.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 6.3 GO:0043034 costamere(GO:0043034)
0.2 1.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 16.4 GO:0016605 PML body(GO:0016605)
0.2 5.5 GO:0042581 specific granule(GO:0042581)
0.2 1.9 GO:0030008 TRAPP complex(GO:0030008)
0.2 9.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.2 1.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 5.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 14.8 GO:0030018 Z disc(GO:0030018)
0.1 0.9 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 2.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 16.0 GO:0005795 Golgi stack(GO:0005795)
0.1 1.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.3 GO:0017119 Golgi transport complex(GO:0017119)
0.1 6.2 GO:0000793 condensed chromosome(GO:0000793)
0.1 2.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.1 4.4 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.7 GO:0070852 cell body fiber(GO:0070852)
0.1 2.6 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 2.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 1.8 GO:0071564 npBAF complex(GO:0071564)
0.1 1.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.5 GO:0032039 integrator complex(GO:0032039)
0.1 18.5 GO:0005635 nuclear envelope(GO:0005635)
0.1 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701) junctional membrane complex(GO:0030314)
0.1 0.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 3.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 0.4 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 1.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:0005675 core TFIIH complex(GO:0000439) holo TFIIH complex(GO:0005675)
0.1 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 4.2 GO:0005884 actin filament(GO:0005884)
0.0 0.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.4 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0000792 heterochromatin(GO:0000792)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
13.9 41.6 GO:0004170 dUTP diphosphatase activity(GO:0004170)
13.6 54.3 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
13.0 52.0 GO:0004743 pyruvate kinase activity(GO:0004743)
12.1 36.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
11.0 44.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
10.7 85.5 GO:0044388 small protein activating enzyme binding(GO:0044388)
10.1 30.3 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
10.0 29.9 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
9.9 39.5 GO:0002060 purine nucleobase binding(GO:0002060)
9.6 67.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
9.5 37.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
9.2 27.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
8.7 43.7 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
8.3 25.0 GO:0034511 U3 snoRNA binding(GO:0034511)
7.7 30.6 GO:0000104 succinate dehydrogenase activity(GO:0000104)
7.6 22.8 GO:0017130 poly(C) RNA binding(GO:0017130)
7.2 43.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
7.2 21.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
7.1 21.2 GO:0098770 FBXO family protein binding(GO:0098770)
6.6 26.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
6.5 45.8 GO:0030620 U2 snRNA binding(GO:0030620)
6.5 90.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
6.1 18.4 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
6.1 18.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
6.0 84.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
6.0 18.0 GO:0001069 regulatory region RNA binding(GO:0001069)
5.8 69.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
5.7 40.2 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
5.6 11.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
5.6 16.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
5.5 22.1 GO:0032143 single thymine insertion binding(GO:0032143)
5.4 21.6 GO:0005046 KDEL sequence binding(GO:0005046)
5.4 26.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
5.3 16.0 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
5.3 15.9 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
5.3 15.8 GO:0004797 thymidine kinase activity(GO:0004797)
5.2 15.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
5.2 36.3 GO:0030621 U4 snRNA binding(GO:0030621)
5.1 45.8 GO:0035174 histone serine kinase activity(GO:0035174)
5.0 25.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
5.0 10.1 GO:0016531 copper chaperone activity(GO:0016531)
5.0 15.0 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
4.9 34.3 GO:1990226 histone methyltransferase binding(GO:1990226)
4.9 34.2 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
4.8 144.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
4.7 18.9 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
4.7 37.8 GO:1990446 U1 snRNP binding(GO:1990446)
4.7 14.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
4.6 9.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
4.6 36.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
4.5 22.3 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
4.5 22.3 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
4.4 13.2 GO:0032767 copper-dependent protein binding(GO:0032767)
4.4 21.8 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
4.3 17.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
4.2 89.2 GO:0035173 histone kinase activity(GO:0035173)
4.2 75.8 GO:0001054 RNA polymerase I activity(GO:0001054)
4.2 12.6 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
4.1 40.9 GO:0030911 TPR domain binding(GO:0030911)
4.0 27.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
3.9 11.7 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
3.8 49.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
3.8 15.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
3.8 22.6 GO:0000400 four-way junction DNA binding(GO:0000400)
3.7 11.2 GO:0035529 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
3.7 14.9 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
3.7 14.9 GO:0005346 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
3.7 22.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
3.6 14.5 GO:0004074 biliverdin reductase activity(GO:0004074)
3.6 25.3 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
3.6 10.7 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
3.5 10.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
3.5 10.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
3.5 17.6 GO:0008536 Ran GTPase binding(GO:0008536)
3.5 10.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
3.5 20.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
3.5 24.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
3.4 20.6 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
3.4 13.7 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
3.4 13.6 GO:0004047 aminomethyltransferase activity(GO:0004047)
3.4 105.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
3.4 13.6 GO:0036033 mediator complex binding(GO:0036033)
3.4 97.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
3.3 6.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
3.3 36.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
3.3 6.6 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
3.3 9.9 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
3.3 52.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
3.3 172.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
3.3 9.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
3.2 25.8 GO:0008312 7S RNA binding(GO:0008312)
3.2 9.6 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
3.2 41.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
3.1 6.3 GO:0043398 HLH domain binding(GO:0043398)
3.1 34.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
3.1 12.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
3.1 137.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
3.1 18.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
3.1 34.1 GO:0001222 transcription corepressor binding(GO:0001222)
3.1 18.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
3.1 15.4 GO:0000405 bubble DNA binding(GO:0000405)
3.0 33.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
3.0 18.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
3.0 41.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
3.0 20.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
2.9 17.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
2.9 28.8 GO:0031386 protein tag(GO:0031386)
2.8 22.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
2.8 28.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
2.8 16.7 GO:0003998 acylphosphatase activity(GO:0003998)
2.8 24.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
2.7 16.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
2.7 8.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
2.7 10.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
2.7 29.4 GO:0015266 protein channel activity(GO:0015266)
2.7 13.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
2.7 8.0 GO:0000150 recombinase activity(GO:0000150)
2.6 10.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
2.6 10.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
2.6 537.5 GO:0003735 structural constituent of ribosome(GO:0003735)
2.6 7.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.6 28.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
2.5 10.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
2.5 7.5 GO:0048030 disaccharide binding(GO:0048030)
2.5 7.4 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
2.5 9.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
2.4 7.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
2.4 65.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
2.4 21.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
2.4 9.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
2.4 49.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
2.3 14.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
2.3 11.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
2.3 11.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
2.3 9.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
2.3 31.6 GO:0016018 cyclosporin A binding(GO:0016018)
2.2 11.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
2.2 17.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
2.2 13.0 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
2.1 8.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
2.1 32.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
2.1 8.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
2.1 19.1 GO:0035877 death effector domain binding(GO:0035877)
2.1 10.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
2.1 14.7 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
2.1 8.3 GO:0035473 lipase binding(GO:0035473)
2.1 20.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
2.1 10.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
2.0 8.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.0 10.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
2.0 13.9 GO:0061133 endopeptidase activator activity(GO:0061133)
2.0 5.9 GO:0070404 NADH binding(GO:0070404)
1.9 5.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.9 22.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
1.9 24.6 GO:0030515 snoRNA binding(GO:0030515)
1.9 7.6 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.9 13.2 GO:0050815 phosphoserine binding(GO:0050815)
1.9 24.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
1.9 5.6 GO:0098519 polynucleotide phosphatase activity(GO:0098518) nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.9 9.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.8 5.5 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
1.8 5.5 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
1.8 11.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.8 1.8 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
1.8 5.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
1.8 5.3 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
1.8 8.8 GO:1990254 keratin filament binding(GO:1990254)
1.8 5.3 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
1.8 12.3 GO:0070087 chromo shadow domain binding(GO:0070087)
1.7 29.0 GO:0008266 poly(U) RNA binding(GO:0008266)
1.7 10.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.7 5.0 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.6 9.8 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
1.6 4.9 GO:0015235 cobalamin transporter activity(GO:0015235)
1.6 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
1.6 9.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.6 6.4 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
1.6 29.9 GO:0070628 proteasome binding(GO:0070628)
1.6 12.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
1.5 1.5 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.5 16.7 GO:0019206 nucleoside kinase activity(GO:0019206)
1.5 7.5 GO:0016403 dimethylargininase activity(GO:0016403)
1.5 130.6 GO:0003697 single-stranded DNA binding(GO:0003697)
1.5 4.5 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.5 10.3 GO:0004017 adenylate kinase activity(GO:0004017)
1.5 8.8 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
1.5 26.2 GO:0070182 DNA polymerase binding(GO:0070182)
1.5 16.0 GO:0017070 U6 snRNA binding(GO:0017070)
1.4 15.9 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.4 11.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.4 4.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
1.4 9.6 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
1.4 6.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
1.4 8.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.3 27.0 GO:0000339 RNA cap binding(GO:0000339)
1.3 6.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
1.3 8.0 GO:0017018 myosin phosphatase activity(GO:0017018)
1.3 13.3 GO:0070034 telomerase RNA binding(GO:0070034)
1.3 18.6 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
1.3 4.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.3 14.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
1.3 2.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.3 35.0 GO:0043015 gamma-tubulin binding(GO:0043015)
1.3 68.6 GO:0019894 kinesin binding(GO:0019894)
1.3 10.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.3 6.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
1.3 22.8 GO:0035497 cAMP response element binding(GO:0035497)
1.3 12.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.3 51.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
1.2 3.5 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
1.1 9.1 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
1.1 5.6 GO:0097016 L27 domain binding(GO:0097016)
1.1 3.3 GO:0070025 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
1.1 19.7 GO:0070403 NAD+ binding(GO:0070403)
1.1 69.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
1.1 2.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
1.1 6.4 GO:0050733 RS domain binding(GO:0050733)
1.1 64.6 GO:0070063 RNA polymerase binding(GO:0070063)
1.0 6.2 GO:0023029 MHC class Ib protein binding(GO:0023029) TAP2 binding(GO:0046979)
1.0 14.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.0 39.0 GO:0019201 guanylate kinase activity(GO:0004385) nucleotide kinase activity(GO:0019201)
1.0 1.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.0 23.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.0 3.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
1.0 16.7 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.0 2.9 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
1.0 3.9 GO:0008410 CoA-transferase activity(GO:0008410)
1.0 98.2 GO:0043130 ubiquitin binding(GO:0043130)
0.9 15.1 GO:0008143 poly(A) binding(GO:0008143)
0.9 3.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.9 9.2 GO:0048156 tau protein binding(GO:0048156)
0.9 9.2 GO:0045545 syndecan binding(GO:0045545)
0.9 105.6 GO:0051082 unfolded protein binding(GO:0051082)
0.9 16.8 GO:0097602 cullin family protein binding(GO:0097602)
0.9 11.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.9 3.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.9 11.4 GO:0019843 rRNA binding(GO:0019843)
0.9 6.0 GO:0001727 lipid kinase activity(GO:0001727)
0.8 3.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.8 17.7 GO:0008242 omega peptidase activity(GO:0008242)
0.8 6.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.8 10.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.8 6.6 GO:0042731 PH domain binding(GO:0042731)
0.8 2.5 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.8 8.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.8 4.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.8 7.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.8 12.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.8 16.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.8 12.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.8 10.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.8 3.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.8 21.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.8 7.8 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.8 54.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.8 2.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.8 30.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.8 15.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.8 13.5 GO:0044548 S100 protein binding(GO:0044548)
0.7 3.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.7 8.1 GO:0008432 JUN kinase binding(GO:0008432)
0.7 14.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.7 23.6 GO:0043531 ADP binding(GO:0043531)
0.7 34.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.7 3.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.7 28.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.7 19.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.7 16.4 GO:0005123 death receptor binding(GO:0005123)
0.7 17.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.7 4.7 GO:0004046 aminoacylase activity(GO:0004046)
0.7 2.0 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.7 4.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.7 2.6 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.7 6.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.6 7.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.6 9.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.6 8.7 GO:0043495 protein anchor(GO:0043495)
0.6 8.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 7.2 GO:0008301 DNA binding, bending(GO:0008301)
0.6 25.5 GO:0004386 helicase activity(GO:0004386)
0.5 4.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.5 13.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.5 3.2 GO:0045569 TRAIL binding(GO:0045569)
0.5 3.6 GO:0016421 CoA carboxylase activity(GO:0016421)
0.5 17.6 GO:0032451 demethylase activity(GO:0032451)
0.5 7.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.5 8.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.5 2.3 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.5 18.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.4 3.6 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.4 5.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.4 2.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.4 10.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 5.5 GO:0009881 photoreceptor activity(GO:0009881)
0.4 10.1 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.4 6.6 GO:0004697 protein kinase C activity(GO:0004697)
0.4 7.0 GO:0008483 transaminase activity(GO:0008483)
0.4 56.0 GO:0044325 ion channel binding(GO:0044325)
0.4 10.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 5.3 GO:0004985 opioid receptor activity(GO:0004985)
0.4 11.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 3.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 5.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 2.0 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.4 1.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 29.9 GO:0003777 microtubule motor activity(GO:0003777)
0.4 14.0 GO:0005080 protein kinase C binding(GO:0005080)
0.4 14.8 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.4 7.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.4 2.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.4 39.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.4 7.3 GO:0005537 mannose binding(GO:0005537)
0.4 2.6 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 6.6 GO:0070064 proline-rich region binding(GO:0070064)
0.4 2.9 GO:0045159 myosin II binding(GO:0045159)
0.4 3.9 GO:0035198 miRNA binding(GO:0035198)
0.4 18.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.4 59.6 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.3 13.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 1.4 GO:0016417 fatty acid synthase activity(GO:0004312) S-acyltransferase activity(GO:0016417)
0.3 2.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.3 8.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.3 6.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.3 6.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.3 1.0 GO:0015926 glucosidase activity(GO:0015926)
0.3 3.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 6.0 GO:0019239 deaminase activity(GO:0019239)
0.3 3.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.3 1.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 4.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 13.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.3 5.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 29.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 7.0 GO:0042169 SH2 domain binding(GO:0042169)
0.3 1.1 GO:0004966 galanin receptor activity(GO:0004966)
0.3 9.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.3 3.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 2.6 GO:0043621 protein self-association(GO:0043621)
0.3 0.8 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.3 80.7 GO:0045296 cadherin binding(GO:0045296)
0.3 1.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 1.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.2 0.2 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.2 4.2 GO:0051400 BH domain binding(GO:0051400)
0.2 1.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 8.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.2 5.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 0.9 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 3.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 2.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 5.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 1.5 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 2.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 3.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.2 2.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 4.2 GO:0004871 signal transducer activity(GO:0004871)
0.2 1.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 6.4 GO:0032947 protein complex scaffold(GO:0032947)
0.1 7.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 1.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 3.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 8.6 GO:0051117 ATPase binding(GO:0051117)
0.1 9.4 GO:0030165 PDZ domain binding(GO:0030165)
0.1 108.6 GO:0003723 RNA binding(GO:0003723)
0.1 2.6 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 13.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 9.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 3.5 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.8 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.2 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.0 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 2.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 3.0 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.7 GO:0008565 protein transporter activity(GO:0008565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 88.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
3.0 83.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
2.9 149.9 PID MYC PATHWAY C-MYC pathway
2.9 34.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
2.1 122.5 PID PLK1 PATHWAY PLK1 signaling events
2.1 100.9 PID ATR PATHWAY ATR signaling pathway
2.0 4.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
2.0 229.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
1.6 84.8 PID AURORA B PATHWAY Aurora B signaling
1.4 6.8 PID WNT SIGNALING PATHWAY Wnt signaling network
1.3 121.9 PID E2F PATHWAY E2F transcription factor network
1.2 17.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.1 18.0 PID TRAIL PATHWAY TRAIL signaling pathway
1.1 34.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
1.0 6.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
1.0 51.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.9 17.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.9 11.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.8 31.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.8 42.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.7 16.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.7 51.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.7 47.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.7 13.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.6 57.4 PID P73PATHWAY p73 transcription factor network
0.6 8.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.6 24.7 PID P53 REGULATION PATHWAY p53 pathway
0.6 56.2 PID CMYB PATHWAY C-MYB transcription factor network
0.6 8.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.6 40.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.6 10.3 PID FOXO PATHWAY FoxO family signaling
0.6 24.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.6 23.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.5 10.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.5 19.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.5 38.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.5 2.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.5 7.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.5 27.4 PID AP1 PATHWAY AP-1 transcription factor network
0.5 47.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.5 8.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.4 3.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.4 11.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.4 6.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.4 7.3 PID ARF 3PATHWAY Arf1 pathway
0.4 10.1 PID RHOA PATHWAY RhoA signaling pathway
0.4 4.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.4 16.8 PID LKB1 PATHWAY LKB1 signaling events
0.3 13.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 19.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.3 5.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.3 12.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 5.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 12.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 10.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 4.1 PID RAS PATHWAY Regulation of Ras family activation
0.2 0.9 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.2 5.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 2.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 10.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 4.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.8 PID NOTCH PATHWAY Notch signaling pathway
0.1 2.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 0.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 97.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
5.6 101.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
5.5 98.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
5.3 5.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
5.0 80.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
4.8 76.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
4.0 100.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
3.9 23.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
3.3 39.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
3.2 84.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
3.2 336.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
3.0 230.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
2.9 246.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
2.7 86.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.7 37.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
2.6 71.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
2.5 85.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
2.4 54.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
2.3 84.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
2.3 44.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
2.3 74.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
2.3 124.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
2.3 70.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
2.2 51.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
2.2 35.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
2.2 37.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
2.1 15.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
2.1 10.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
2.0 88.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.9 17.4 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
1.9 46.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
1.9 17.3 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
1.9 52.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.8 18.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
1.8 51.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
1.8 65.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
1.8 17.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.8 7.1 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
1.7 62.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
1.7 67.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.7 57.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
1.7 20.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.7 162.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
1.6 248.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
1.5 30.8 REACTOME KINESINS Genes involved in Kinesins
1.5 58.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
1.4 25.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.4 32.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
1.4 26.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
1.4 37.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
1.4 27.4 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
1.4 32.4 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
1.3 38.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.3 6.5 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
1.3 64.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.2 12.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.2 11.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
1.2 8.6 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
1.2 42.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
1.2 14.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.2 34.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
1.1 4.6 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
1.1 18.7 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
1.1 8.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.1 195.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.0 10.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.0 17.7 REACTOME METABOLISM OF NUCLEOTIDES Genes involved in Metabolism of nucleotides
1.0 18.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
1.0 64.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.9 60.3 REACTOME TRANSLATION Genes involved in Translation
0.9 27.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.9 14.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.9 10.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.9 2.6 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.8 9.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.8 21.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.7 13.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.7 10.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.7 12.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.7 2.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.7 18.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.7 19.3 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.6 11.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.6 22.8 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.5 14.9 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.5 9.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.5 17.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 1.3 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.4 9.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 8.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 4.7 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.4 7.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.4 18.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.4 5.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 29.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.4 8.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4 3.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 2.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.4 11.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.4 2.1 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.4 10.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 3.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 4.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 35.6 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.3 13.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 6.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 12.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 13.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 8.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 1.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 8.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 4.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 2.6 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.2 4.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 3.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 3.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 7.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 8.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 10.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 3.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.7 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.1 5.2 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 3.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 6.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 1.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.2 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 1.9 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation