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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for E2F3

Z-value: 3.18

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Transcription factors associated with E2F3

Gene Symbol Gene ID Gene Info
E2F3
ENSG00000112242.10 E2F transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F3hg19_v2_chr6_+_20403997_204040340.593.8e-22Click!

Activity profile of E2F3 motif

Sorted Z-values of E2F3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_91537723 68.65 ENST00000394249.3
ENST00000559811.1
ENST00000442656.2
ENST00000557905.1
ENST00000361919.3
PRC1
protein regulator of cytokinesis 1
chr17_+_73201754 63.43 ENST00000583569.1
ENST00000245544.4
ENST00000579324.1
ENST00000541827.1
ENST00000579298.1
ENST00000447371.2
NUP85
nucleoporin 85kDa
chr10_-_58120996 54.71 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZWINT
ZW10 interacting kinetochore protein
chr5_+_177631497 46.01 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr2_+_10262857 44.05 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr10_+_62538248 42.45 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr18_-_54318353 41.49 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr20_+_25388293 41.20 ENST00000262460.4
ENST00000429262.2
GINS1
GINS complex subunit 1 (Psf1 homolog)
chr10_+_62538089 39.75 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr19_-_55919087 39.55 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
UBE2S
ubiquitin-conjugating enzyme E2S
chr3_+_112709804 38.25 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr6_-_38670897 36.93 ENST00000373365.4
GLO1
glyoxalase I
chr2_+_181845843 35.69 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr8_-_101963482 34.90 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_-_185542817 34.70 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr11_-_14380664 34.58 ENST00000545643.1
ENST00000256196.4
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr11_+_118272328 34.51 ENST00000524422.1
ATP5L
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr7_+_26240776 34.26 ENST00000337620.4
CBX3
chromobox homolog 3
chr1_+_203830703 33.49 ENST00000414487.2
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr14_+_51706886 33.34 ENST00000457354.2
TMX1
thioredoxin-related transmembrane protein 1
chr5_+_159848807 33.00 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr9_-_179018 32.92 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
CBWD1
COBW domain containing 1
chr8_+_91013676 32.74 ENST00000519410.1
ENST00000522161.1
ENST00000517761.1
ENST00000520227.1
DECR1
2,4-dienoyl CoA reductase 1, mitochondrial
chr6_+_52535878 32.47 ENST00000211314.4
TMEM14A
transmembrane protein 14A
chr15_-_72523454 32.26 ENST00000565154.1
ENST00000565184.1
ENST00000389093.3
ENST00000449901.2
ENST00000335181.5
ENST00000319622.6
PKM
pyruvate kinase, muscle
chr20_-_60718430 32.00 ENST00000370873.4
ENST00000370858.3
PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
chr2_+_181845298 31.72 ENST00000410062.4
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr8_-_81083341 31.63 ENST00000519303.2
TPD52
tumor protein D52
chr1_+_155178481 31.60 ENST00000368376.3
MTX1
metaxin 1
chr1_-_43638168 31.26 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr15_-_66649010 31.15 ENST00000367709.4
ENST00000261881.4
TIPIN
TIMELESS interacting protein
chr7_-_140714739 31.13 ENST00000467334.1
ENST00000324787.5
MRPS33
mitochondrial ribosomal protein S33
chr3_+_52740094 30.32 ENST00000602728.1
SPCS1
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr2_-_69664549 30.32 ENST00000450796.2
ENST00000484177.1
NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr12_+_104609550 30.27 ENST00000525566.1
ENST00000429002.2
TXNRD1
thioredoxin reductase 1
chr5_+_159848854 30.24 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1
pituitary tumor-transforming 1
chr2_+_113403434 30.23 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr15_-_55489097 30.10 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr16_-_85833160 29.96 ENST00000435200.2
EMC8
ER membrane protein complex subunit 8
chr17_+_73257742 29.84 ENST00000579761.1
ENST00000245539.6
MRPS7
mitochondrial ribosomal protein S7
chr7_-_96339132 29.67 ENST00000413065.1
SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr5_+_32585605 28.51 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1
SUB1 homolog (S. cerevisiae)
chr12_-_50419177 28.50 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
RACGAP1
Rac GTPase activating protein 1
chr7_+_16685756 28.34 ENST00000415365.1
ENST00000258761.3
ENST00000433922.2
ENST00000452975.2
ENST00000405202.1
BZW2
basic leucine zipper and W2 domains 2
chr2_+_201171372 28.18 ENST00000409140.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr8_-_48872686 28.01 ENST00000314191.2
ENST00000338368.3
PRKDC
protein kinase, DNA-activated, catalytic polypeptide
chr14_-_68141535 27.76 ENST00000554659.1
VTI1B
vesicle transport through interaction with t-SNAREs 1B
chrX_-_153285395 27.73 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chr5_+_177631523 27.70 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr1_-_54411240 27.59 ENST00000371378.2
HSPB11
heat shock protein family B (small), member 11
chr19_+_33071974 27.47 ENST00000590247.2
ENST00000419343.3
ENST00000592786.1
ENST00000379316.3
PDCD5
programmed cell death 5
chr5_+_1801503 27.46 ENST00000274137.5
ENST00000469176.1
NDUFS6
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr13_+_28194873 27.32 ENST00000302979.3
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr10_-_17659234 27.26 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr14_-_104029013 27.09 ENST00000299204.4
ENST00000557666.1
BAG5
BCL2-associated athanogene 5
chr9_-_70490107 26.99 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr7_-_140714430 26.88 ENST00000393008.3
MRPS33
mitochondrial ribosomal protein S33
chr9_+_100745615 26.73 ENST00000339399.4
ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr19_-_14628645 26.64 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr9_-_111775772 26.46 ENST00000325580.6
ENST00000374593.4
ENST00000374595.4
ENST00000325551.4
CTNNAL1
catenin (cadherin-associated protein), alpha-like 1
chr2_-_10587897 26.32 ENST00000405333.1
ENST00000443218.1
ODC1
ornithine decarboxylase 1
chr10_+_124913930 26.31 ENST00000368858.5
BUB3
BUB3 mitotic checkpoint protein
chr5_-_68665469 26.21 ENST00000217893.5
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr6_+_36562132 26.19 ENST00000373715.6
ENST00000339436.7
SRSF3
serine/arginine-rich splicing factor 3
chr3_-_185542761 26.05 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr19_-_6415695 25.70 ENST00000594496.1
ENST00000594745.1
ENST00000600480.1
KHSRP
KH-type splicing regulatory protein
chr3_-_134093275 25.67 ENST00000513145.1
ENST00000422605.2
AMOTL2
angiomotin like 2
chr2_+_237994519 25.65 ENST00000392008.2
ENST00000409334.1
ENST00000409629.1
COPS8
COP9 signalosome subunit 8
chr13_-_22178284 25.40 ENST00000468222.2
ENST00000382374.4
MICU2
mitochondrial calcium uptake 2
chr7_-_86849025 25.33 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr5_-_68665084 24.71 ENST00000509462.1
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr5_+_5422778 24.63 ENST00000296564.7
KIAA0947
KIAA0947
chr12_+_93861264 24.46 ENST00000549982.1
ENST00000361630.2
MRPL42
mitochondrial ribosomal protein L42
chr1_-_43637915 24.43 ENST00000236051.2
EBNA1BP2
EBNA1 binding protein 2
chr12_+_93861282 24.27 ENST00000552217.1
ENST00000393128.4
ENST00000547098.1
MRPL42
mitochondrial ribosomal protein L42
chr14_+_97263641 24.26 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr7_+_141438118 24.15 ENST00000265304.6
ENST00000498107.1
ENST00000467681.1
ENST00000465582.1
ENST00000463093.1
SSBP1
single-stranded DNA binding protein 1, mitochondrial
chr10_+_95256356 24.04 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr5_-_68665815 23.93 ENST00000380818.3
ENST00000328663.4
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr20_-_54967187 23.79 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA
aurora kinase A
chr2_+_200820269 23.78 ENST00000392290.1
C2orf47
chromosome 2 open reading frame 47
chr2_-_170681324 23.73 ENST00000409340.1
METTL5
methyltransferase like 5
chr14_+_20937538 23.67 ENST00000361505.5
ENST00000553591.1
PNP
purine nucleoside phosphorylase
chr15_+_48623600 23.51 ENST00000558813.1
ENST00000331200.3
ENST00000558472.1
DUT
deoxyuridine triphosphatase
chr14_-_102553371 23.39 ENST00000553585.1
ENST00000216281.8
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr1_-_54411255 23.37 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr2_-_69664586 23.30 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr1_+_948803 23.23 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr15_-_101835414 23.10 ENST00000254193.6
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr1_+_155178518 22.96 ENST00000316721.4
MTX1
metaxin 1
chr4_-_100871506 22.84 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr20_+_47662805 22.72 ENST00000262982.2
ENST00000542325.1
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr4_-_170679024 22.72 ENST00000393381.2
C4orf27
chromosome 4 open reading frame 27
chr15_-_101835110 22.69 ENST00000560496.1
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr11_+_105948216 22.51 ENST00000278618.4
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr20_-_31989307 22.45 ENST00000473997.1
ENST00000544843.1
ENST00000346416.2
ENST00000357886.4
ENST00000339269.5
CDK5RAP1
CDK5 regulatory subunit associated protein 1
chr18_+_657733 22.19 ENST00000323250.5
ENST00000323224.7
TYMS
thymidylate synthetase
chr4_-_1714037 22.10 ENST00000488267.1
ENST00000429429.2
ENST00000480936.1
SLBP
stem-loop binding protein
chr2_+_48010312 22.10 ENST00000540021.1
MSH6
mutS homolog 6
chr2_+_181845074 22.09 ENST00000602959.1
ENST00000602479.1
ENST00000392415.2
ENST00000602291.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr2_+_264869 22.03 ENST00000272067.6
ENST00000272065.5
ENST00000407983.3
ACP1
acid phosphatase 1, soluble
chr9_+_127624387 22.02 ENST00000353214.2
ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr11_+_18416103 21.84 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
LDHA
lactate dehydrogenase A
chr15_+_77224045 21.84 ENST00000320963.5
ENST00000394883.3
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr9_+_70856899 21.79 ENST00000377342.5
ENST00000478048.1
CBWD3
COBW domain containing 3
chr7_+_12727250 21.78 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr4_-_185655278 21.73 ENST00000281453.5
MLF1IP
centromere protein U
chr17_-_47785265 21.68 ENST00000511763.1
ENST00000515850.1
ENST00000415270.2
ENST00000240333.6
SLC35B1
solute carrier family 35, member B1
chr15_-_85259294 21.67 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr6_-_5261141 21.62 ENST00000330636.4
ENST00000500576.2
LYRM4
LYR motif containing 4
chr4_-_1713977 21.57 ENST00000318386.4
SLBP
stem-loop binding protein
chr19_-_48894762 21.57 ENST00000600980.1
ENST00000330720.2
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr1_-_211752073 21.56 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr8_+_91013577 21.54 ENST00000220764.2
DECR1
2,4-dienoyl CoA reductase 1, mitochondrial
chr1_+_8021713 21.49 ENST00000338639.5
ENST00000493678.1
ENST00000377493.5
PARK7
parkinson protein 7
chr3_-_134093395 21.46 ENST00000249883.5
AMOTL2
angiomotin like 2
chr4_-_2965052 21.41 ENST00000398071.4
ENST00000502735.1
ENST00000314262.6
ENST00000416614.2
NOP14
NOP14 nucleolar protein
chr1_+_44440575 21.31 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr12_-_112856623 21.31 ENST00000551291.2
RPL6
ribosomal protein L6
chr1_+_87170577 21.29 ENST00000482504.1
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr21_-_40555393 21.28 ENST00000380900.2
PSMG1
proteasome (prosome, macropain) assembly chaperone 1
chr3_+_172468472 21.28 ENST00000232458.5
ENST00000392692.3
ECT2
epithelial cell transforming sequence 2 oncogene
chr12_-_15942503 21.22 ENST00000281172.5
EPS8
epidermal growth factor receptor pathway substrate 8
chr11_+_102217936 21.15 ENST00000532832.1
ENST00000530675.1
ENST00000533742.1
ENST00000227758.2
ENST00000532672.1
ENST00000531259.1
ENST00000527465.1
BIRC2
baculoviral IAP repeat containing 2
chr8_+_26149007 21.11 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr14_+_58711539 20.88 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr22_-_29949634 20.84 ENST00000397872.1
ENST00000397871.1
ENST00000440771.1
THOC5
THO complex 5
chr13_+_76123883 20.81 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr9_-_69262509 20.74 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
CBWD6
COBW domain containing 6
chr7_-_16685422 20.67 ENST00000306999.2
ANKMY2
ankyrin repeat and MYND domain containing 2
chr15_+_59397275 20.64 ENST00000288207.2
CCNB2
cyclin B2
chr2_-_47168850 20.63 ENST00000409207.1
MCFD2
multiple coagulation factor deficiency 2
chr10_+_43278217 20.63 ENST00000374518.5
BMS1
BMS1 ribosome biogenesis factor
chr4_-_120988229 20.62 ENST00000296509.6
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr2_+_114195268 20.62 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2
COBW domain containing 2
chr6_-_79787902 20.52 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr12_+_133264635 20.49 ENST00000545677.1
ENST00000537262.1
PXMP2
RP13-672B3.2
peroxisomal membrane protein 2, 22kDa
Uncharacterized protein
chr5_+_10250328 20.45 ENST00000515390.1
CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr19_-_23941639 20.39 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
ZNF681
zinc finger protein 681
chr1_-_32801825 20.39 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr5_-_143550159 20.34 ENST00000448443.2
ENST00000513112.1
ENST00000519064.1
ENST00000274496.5
YIPF5
Yip1 domain family, member 5
chr3_+_139063372 20.24 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr14_+_54863739 20.06 ENST00000541304.1
CDKN3
cyclin-dependent kinase inhibitor 3
chrX_-_153718953 20.06 ENST00000369649.4
ENST00000393586.1
SLC10A3
solute carrier family 10, member 3
chr6_+_10748019 20.05 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
SYCP2L
TMEM14B
synaptonemal complex protein 2-like
transmembrane protein 14B
chr5_+_112196919 20.04 ENST00000505459.1
ENST00000282999.3
ENST00000515463.1
SRP19
signal recognition particle 19kDa
chr9_-_95055956 19.99 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chrX_-_153707246 19.84 ENST00000407062.1
LAGE3
L antigen family, member 3
chr15_-_72523924 19.70 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
PKM
pyruvate kinase, muscle
chr18_-_47018897 19.67 ENST00000418495.1
RPL17
ribosomal protein L17
chr1_+_90287480 19.45 ENST00000394593.3
LRRC8D
leucine rich repeat containing 8 family, member D
chr15_+_59397298 19.45 ENST00000559622.1
CCNB2
cyclin B2
chr7_-_64023441 19.44 ENST00000309683.6
ZNF680
zinc finger protein 680
chr1_+_161719552 19.43 ENST00000367943.4
DUSP12
dual specificity phosphatase 12
chr7_+_98923505 19.43 ENST00000432884.2
ENST00000262942.5
ARPC1A
actin related protein 2/3 complex, subunit 1A, 41kDa
chr7_+_73097890 19.37 ENST00000265758.2
ENST00000423166.2
ENST00000423497.1
WBSCR22
Williams Beuren syndrome chromosome region 22
chr1_+_155658849 19.34 ENST00000368336.5
ENST00000343043.3
ENST00000421487.2
ENST00000535183.1
ENST00000465375.1
ENST00000470830.1
DAP3
death associated protein 3
chr14_-_104028595 19.29 ENST00000337322.4
ENST00000445922.2
BAG5
BCL2-associated athanogene 5
chr19_+_49497121 19.27 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr15_-_85259330 19.21 ENST00000560266.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr11_+_70049269 19.12 ENST00000301838.4
FADD
Fas (TNFRSF6)-associated via death domain
chr19_-_10530784 19.04 ENST00000593124.1
CDC37
cell division cycle 37
chr1_+_161284047 19.00 ENST00000367975.2
ENST00000342751.4
ENST00000432287.2
ENST00000392169.2
ENST00000513009.1
SDHC
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
chr8_-_80942139 19.00 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
MRPS28
mitochondrial ribosomal protein S28
chr4_+_17812525 18.99 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr10_+_124913793 18.97 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3
BUB3 mitotic checkpoint protein
chr5_+_34915444 18.91 ENST00000336767.5
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr12_+_57623869 18.89 ENST00000414700.3
ENST00000557703.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr14_+_54863682 18.79 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
CDKN3
cyclin-dependent kinase inhibitor 3
chr15_+_66797455 18.79 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr20_-_57617831 18.77 ENST00000371033.5
ENST00000355937.4
SLMO2
slowmo homolog 2 (Drosophila)
chr1_-_8938736 18.57 ENST00000234590.4
ENO1
enolase 1, (alpha)
chr18_+_20513278 18.53 ENST00000327155.5
RBBP8
retinoblastoma binding protein 8
chr17_+_1944790 18.51 ENST00000575162.1
DPH1
diphthamide biosynthesis 1
chr18_-_47018769 18.51 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17
ribosomal protein L17
chr2_-_207024134 18.49 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_-_42588338 18.27 ENST00000234301.2
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr1_+_166808692 18.25 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr2_-_84686552 18.15 ENST00000393868.2
SUCLG1
succinate-CoA ligase, alpha subunit
chr15_+_48623208 18.14 ENST00000559935.1
ENST00000559416.1
DUT
deoxyuridine triphosphatase
chr3_+_158519654 18.09 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chr9_+_116037922 18.08 ENST00000374198.4
PRPF4
pre-mRNA processing factor 4
chr2_-_170430277 18.05 ENST00000438035.1
ENST00000453929.2
FASTKD1
FAST kinase domains 1
chr3_+_151986709 18.02 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr19_-_1095330 17.91 ENST00000586746.1
POLR2E
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr5_-_79950371 17.89 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
DHFR
dihydrofolate reductase
chrX_-_153718988 17.81 ENST00000263512.4
ENST00000393587.4
ENST00000453912.1
SLC10A3
solute carrier family 10, member 3
chr11_-_34938039 17.80 ENST00000395787.3
APIP
APAF1 interacting protein
chr7_-_138794081 17.77 ENST00000464606.1
ZC3HAV1
zinc finger CCCH-type, antiviral 1
chr14_-_50154921 17.76 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2
polymerase (DNA directed), epsilon 2, accessory subunit
chr1_-_63988846 17.74 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr8_-_63951730 17.69 ENST00000260118.6
GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr20_+_52824367 17.59 ENST00000371419.2
PFDN4
prefoldin subunit 4
chr2_-_174828892 17.52 ENST00000418194.2
SP3
Sp3 transcription factor
chr20_+_23331373 17.49 ENST00000254998.2
NXT1
NTF2-like export factor 1
chr14_-_102552659 17.49 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr7_-_87849340 17.42 ENST00000419179.1
ENST00000265729.2
SRI
sorcin
chr1_-_246729544 17.41 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr1_+_54411715 17.40 ENST00000371370.3
ENST00000371368.1
LRRC42
leucine rich repeat containing 42
chr3_-_63849571 17.37 ENST00000295899.5
THOC7
THO complex 7 homolog (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
15.1 45.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
13.9 83.5 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
13.9 41.6 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
12.6 37.7 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
12.1 36.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
11.6 150.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
11.2 44.6 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
11.1 55.3 GO:0009438 methylglyoxal metabolic process(GO:0009438)
10.8 32.5 GO:0044209 AMP salvage(GO:0044209)
10.2 40.9 GO:0043335 protein unfolding(GO:0043335)
10.0 29.9 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
9.3 37.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
9.2 73.9 GO:1903333 negative regulation of protein folding(GO:1903333)
9.0 45.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
8.8 26.3 GO:0006738 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
8.7 43.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
8.7 52.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
8.4 33.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
8.2 32.8 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
8.1 24.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
8.1 32.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
7.9 23.8 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
7.7 31.0 GO:0009202 dTTP biosynthetic process(GO:0006235) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
7.7 23.2 GO:0007113 endomitotic cell cycle(GO:0007113)
7.7 23.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
7.5 44.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
7.4 29.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
7.2 21.7 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
7.2 35.8 GO:0061198 fungiform papilla formation(GO:0061198)
7.1 21.4 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
7.1 21.2 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
7.0 7.0 GO:0048254 snoRNA localization(GO:0048254)
6.9 48.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
6.8 34.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
6.7 20.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
6.6 26.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
6.4 32.0 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
6.3 19.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
6.3 19.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
6.3 37.6 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
6.3 6.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
6.2 31.1 GO:0048478 replication fork protection(GO:0048478)
6.1 24.3 GO:0090166 Golgi disassembly(GO:0090166)
5.9 17.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
5.8 28.8 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
5.7 17.2 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
5.6 16.8 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
5.6 16.7 GO:0006097 glyoxylate cycle(GO:0006097)
5.5 44.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
5.4 16.3 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
5.4 27.0 GO:0097501 stress response to metal ion(GO:0097501)
5.3 16.0 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
5.3 37.1 GO:0000710 meiotic mismatch repair(GO:0000710)
5.2 15.6 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
5.1 15.4 GO:1901873 regulation of post-translational protein modification(GO:1901873)
5.1 35.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
5.0 372.5 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
5.0 15.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
5.0 14.9 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
4.9 39.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
4.9 34.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
4.8 19.1 GO:0072683 T cell extravasation(GO:0072683)
4.7 18.9 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
4.7 42.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
4.6 41.7 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
4.6 101.5 GO:0006465 signal peptide processing(GO:0006465)
4.6 13.7 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
4.5 9.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
4.5 8.9 GO:0042256 mature ribosome assembly(GO:0042256)
4.4 48.7 GO:0090168 Golgi reassembly(GO:0090168)
4.4 13.1 GO:0051685 maintenance of ER location(GO:0051685)
4.4 17.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
4.3 12.8 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
4.2 37.6 GO:0001887 selenium compound metabolic process(GO:0001887)
4.1 20.7 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
4.1 49.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
4.0 12.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
4.0 100.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
4.0 24.0 GO:0031126 snoRNA 3'-end processing(GO:0031126)
4.0 12.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
4.0 15.8 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
3.9 15.4 GO:2000819 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) regulation of nucleotide-excision repair(GO:2000819)
3.8 49.8 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
3.8 22.9 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
3.8 11.5 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
3.8 11.3 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.8 30.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
3.8 22.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
3.8 49.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
3.7 29.8 GO:0015866 ADP transport(GO:0015866)
3.7 11.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
3.7 26.0 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
3.7 14.8 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
3.7 11.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
3.7 25.7 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
3.7 22.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
3.6 21.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
3.6 46.7 GO:0070986 left/right axis specification(GO:0070986)
3.6 10.7 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
3.5 14.2 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
3.5 10.5 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
3.5 13.9 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
3.4 37.9 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
3.4 34.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
3.3 16.7 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
3.3 19.9 GO:0006177 GMP biosynthetic process(GO:0006177)
3.3 22.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
3.3 9.8 GO:0006788 heme oxidation(GO:0006788)
3.2 19.4 GO:0006021 inositol biosynthetic process(GO:0006021)
3.2 22.5 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
3.2 9.6 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
3.2 51.3 GO:0043248 proteasome assembly(GO:0043248)
3.2 9.6 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
3.2 9.6 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
3.2 70.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
3.1 25.2 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
3.1 18.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
3.1 31.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
3.1 6.2 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
3.1 9.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
3.1 46.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
3.1 21.5 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
3.1 15.4 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
3.0 24.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
3.0 36.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
3.0 88.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
3.0 12.1 GO:0006642 triglyceride mobilization(GO:0006642)
3.0 12.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
3.0 8.9 GO:0006740 NADPH regeneration(GO:0006740)
3.0 41.3 GO:0000022 mitotic spindle elongation(GO:0000022)
2.9 5.9 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
2.9 17.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
2.9 23.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.9 17.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
2.9 92.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
2.8 11.3 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
2.8 187.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
2.8 2.8 GO:0030888 regulation of B cell proliferation(GO:0030888)
2.8 30.4 GO:0006089 lactate metabolic process(GO:0006089)
2.7 13.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
2.7 13.6 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.7 13.6 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
2.7 10.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
2.7 13.4 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
2.7 8.0 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
2.7 16.0 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
2.7 26.6 GO:0042407 cristae formation(GO:0042407)
2.7 8.0 GO:1901297 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
2.7 13.3 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
2.7 18.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
2.7 8.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
2.6 303.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
2.6 23.4 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
2.6 10.3 GO:0002317 plasma cell differentiation(GO:0002317)
2.6 23.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.6 17.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
2.5 12.7 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
2.5 10.2 GO:0044375 regulation of peroxisome size(GO:0044375)
2.5 7.6 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
2.5 30.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
2.5 7.5 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
2.5 10.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
2.5 17.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.5 56.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
2.5 2.5 GO:0009441 glycolate metabolic process(GO:0009441)
2.5 9.8 GO:1903826 arginine transmembrane transport(GO:1903826)
2.5 44.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
2.4 7.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
2.4 9.6 GO:0090309 maintenance of DNA methylation(GO:0010216) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
2.4 14.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
2.4 4.7 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
2.4 11.8 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
2.3 28.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
2.3 9.3 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
2.3 6.9 GO:0016074 snoRNA metabolic process(GO:0016074)
2.3 9.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
2.3 11.4 GO:0030047 actin modification(GO:0030047)
2.3 6.8 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
2.3 106.8 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
2.3 15.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
2.3 2.3 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
2.3 4.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
2.3 13.5 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
2.3 22.5 GO:0015939 pantothenate metabolic process(GO:0015939)
2.2 18.0 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
2.2 11.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
2.2 11.1 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
2.2 17.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
2.2 6.6 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
2.2 6.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
2.2 35.0 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
2.2 13.0 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
2.1 115.8 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
2.1 10.7 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
2.1 8.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
2.1 6.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
2.1 6.3 GO:0009726 detection of endogenous stimulus(GO:0009726)
2.1 2.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
2.1 8.2 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
2.1 8.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
2.1 10.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
2.0 6.1 GO:0070668 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
2.0 8.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.0 6.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
2.0 8.0 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
2.0 5.9 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
2.0 4.0 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
2.0 35.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
2.0 7.8 GO:0010815 bradykinin catabolic process(GO:0010815)
1.9 5.8 GO:0046294 formaldehyde catabolic process(GO:0046294)
1.9 42.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.9 9.6 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
1.9 5.7 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.9 11.5 GO:1904044 response to aldosterone(GO:1904044)
1.9 13.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
1.9 7.6 GO:0046108 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
1.9 9.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.9 24.4 GO:0045008 depyrimidination(GO:0045008)
1.9 7.5 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
1.8 1.8 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
1.8 12.9 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.8 5.5 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
1.8 20.2 GO:0051310 metaphase plate congression(GO:0051310)
1.8 14.6 GO:0042262 DNA protection(GO:0042262)
1.8 10.8 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
1.8 5.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
1.8 7.2 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
1.8 3.5 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
1.8 14.1 GO:0070200 establishment of protein localization to telomere(GO:0070200)
1.8 15.9 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
1.8 8.8 GO:0061738 late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.8 124.4 GO:0045454 cell redox homeostasis(GO:0045454)
1.7 8.7 GO:0019401 alditol biosynthetic process(GO:0019401)
1.7 17.2 GO:1900016 negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
1.7 17.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.7 8.5 GO:0009838 abscission(GO:0009838)
1.7 22.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.7 13.5 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
1.7 8.4 GO:0006529 asparagine biosynthetic process(GO:0006529)
1.7 8.4 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.7 6.7 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.6 13.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.6 13.2 GO:0010608 posttranscriptional regulation of gene expression(GO:0010608)
1.6 6.6 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
1.6 11.4 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
1.6 1.6 GO:0006273 lagging strand elongation(GO:0006273)
1.6 17.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.6 19.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.6 36.3 GO:0061157 mRNA destabilization(GO:0061157)
1.6 18.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
1.6 39.4 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
1.6 12.4 GO:0042182 ketone catabolic process(GO:0042182)
1.6 6.2 GO:0046967 cytosol to ER transport(GO:0046967)
1.5 4.6 GO:1904647 response to rotenone(GO:1904647)
1.5 27.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.5 13.7 GO:0090400 stress-induced premature senescence(GO:0090400)
1.5 7.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.5 12.0 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.5 11.8 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.5 2.9 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
1.5 1.5 GO:0021539 subthalamus development(GO:0021539)
1.4 7.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
1.4 10.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.4 64.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
1.4 14.4 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
1.4 7.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.4 5.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
1.4 5.6 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
1.4 7.0 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
1.4 15.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
1.4 57.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
1.4 15.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.4 4.1 GO:0006014 D-ribose metabolic process(GO:0006014)
1.3 25.6 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
1.3 153.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
1.3 10.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.3 5.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
1.3 9.2 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
1.3 6.5 GO:0060356 leucine import(GO:0060356)
1.3 34.6 GO:0006301 postreplication repair(GO:0006301)
1.3 3.8 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.3 7.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.3 5.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
1.3 3.8 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
1.3 6.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
1.2 13.7 GO:0033327 Leydig cell differentiation(GO:0033327)
1.2 9.9 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
1.2 3.6 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
1.2 14.5 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.2 3.6 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.2 21.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.2 19.1 GO:0035067 negative regulation of histone acetylation(GO:0035067)
1.2 22.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.1 9.2 GO:0002934 desmosome organization(GO:0002934)
1.1 4.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
1.1 10.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.1 5.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.1 12.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.1 34.2 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
1.1 3.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
1.1 13.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.1 38.3 GO:0050873 brown fat cell differentiation(GO:0050873)
1.1 3.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
1.1 21.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
1.1 10.7 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
1.1 10.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
1.1 9.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.1 5.3 GO:0075713 establishment of integrated proviral latency(GO:0075713)
1.0 11.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
1.0 9.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
1.0 4.2 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.0 21.8 GO:0008334 histone mRNA metabolic process(GO:0008334)
1.0 12.4 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
1.0 16.4 GO:2001205 negative regulation of osteoclast development(GO:2001205)
1.0 1.0 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of terminal mannose on C branch(GO:0036510) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
1.0 3.0 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.0 7.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.0 8.0 GO:2000210 positive regulation of anoikis(GO:2000210)
1.0 14.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
1.0 4.0 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
1.0 8.0 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.0 4.0 GO:0030242 pexophagy(GO:0030242)
1.0 1.0