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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for E2F7_E2F1

Z-value: 4.92

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Transcription factors associated with E2F7_E2F1

Gene Symbol Gene ID Gene Info
ENSG00000165891.11 E2F transcription factor 7
ENSG00000101412.9 E2F transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F1hg19_v2_chr20_-_32274179_322742130.731.5e-37Click!

Activity profile of E2F7_E2F1 motif

Sorted Z-values of E2F7_E2F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_76183111 154.09 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
thymidine kinase 1, soluble
chr2_+_10262857 153.55 ENST00000304567.5
ribonucleotide reductase M2
chr11_+_4116005 126.04 ENST00000300738.5
ribonucleotide reductase M1
chr2_+_47630255 124.22 ENST00000406134.1
mutS homolog 2
chr18_+_657733 119.47 ENST00000323250.5
ENST00000323224.7
thymidylate synthetase
chr2_+_47630108 117.56 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
mutS homolog 2
chr7_-_99698338 116.37 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr11_+_4116054 115.75 ENST00000423050.2
ribonucleotide reductase M1
chr6_-_52149475 109.53 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
minichromosome maintenance complex component 3
chr4_-_174254823 103.40 ENST00000438704.2
high mobility group box 2
chr7_-_148581251 103.16 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
enhancer of zeste homolog 2 (Drosophila)
chr3_-_186524234 101.27 ENST00000418288.1
ENST00000296273.2
replication factor C (activator 1) 4, 37kDa
chr7_-_148581360 95.58 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
enhancer of zeste homolog 2 (Drosophila)
chr6_-_17706618 95.15 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chr4_-_174256276 95.04 ENST00000296503.5
high mobility group box 2
chr15_-_64673630 94.71 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr12_-_58146128 87.24 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chrX_+_106871713 86.42 ENST00000372435.4
ENST00000372428.4
ENST00000372419.3
ENST00000543248.1
phosphoribosyl pyrophosphate synthetase 1
chr7_-_99699538 85.21 ENST00000343023.6
ENST00000303887.5
minichromosome maintenance complex component 7
chr12_+_96252706 84.96 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr7_-_158497431 84.26 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
non-SMC condensin II complex, subunit G2
chr2_+_172778952 84.02 ENST00000392584.1
ENST00000264108.4
histone acetyltransferase 1
chr12_-_58146048 83.28 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr4_-_1714037 82.95 ENST00000488267.1
ENST00000429429.2
ENST00000480936.1
stem-loop binding protein
chr13_+_34392185 81.93 ENST00000380071.3
replication factor C (activator 1) 3, 38kDa
chr5_+_72112470 80.97 ENST00000447967.2
ENST00000523768.1
transportin 1
chr6_+_30687978 78.49 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr18_+_657578 77.42 ENST00000323274.10
thymidylate synthetase
chr4_+_57302297 75.81 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr3_+_52719936 75.79 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr22_+_20105259 74.97 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr2_-_38978492 74.11 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
serine/arginine-rich splicing factor 7
chr11_-_57103327 73.01 ENST00000529002.1
ENST00000278412.2
structure specific recognition protein 1
chr1_-_24306835 70.57 ENST00000484146.2
serine/arginine-rich splicing factor 10
chr5_+_126112794 68.70 ENST00000261366.5
ENST00000395354.1
lamin B1
chr20_-_2451395 68.67 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
small nuclear ribonucleoprotein polypeptides B and B1
chr22_+_20105012 68.27 ENST00000331821.3
ENST00000411892.1
RAN binding protein 1
chr1_-_33283754 67.59 ENST00000373477.4
tyrosyl-tRNA synthetase
chr8_+_128748308 67.46 ENST00000377970.2
v-myc avian myelocytomatosis viral oncogene homolog
chr16_-_85722530 66.88 ENST00000253462.3
GINS complex subunit 2 (Psf2 homolog)
chr2_-_136633940 65.12 ENST00000264156.2
minichromosome maintenance complex component 6
chr19_+_16187085 64.32 ENST00000300933.4
tropomyosin 4
chr17_-_56084578 63.81 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
serine/arginine-rich splicing factor 1
chr12_-_31479045 63.04 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr4_-_77069533 62.91 ENST00000514987.1
ENST00000458189.2
ENST00000514901.1
ENST00000342467.6
nucleoporin 54kDa
chr9_+_131451480 62.42 ENST00000322030.8
SET nuclear oncogene
chr11_+_85955787 60.25 ENST00000528180.1
embryonic ectoderm development
chr8_-_121457608 59.20 ENST00000306185.3
mitochondrial ribosomal protein L13
chr8_+_48873453 59.16 ENST00000523944.1
minichromosome maintenance complex component 4
chr16_-_12009833 58.83 ENST00000420576.2
G1 to S phase transition 1
chr18_+_29077990 58.58 ENST00000261590.8
desmoglein 2
chr13_+_37574678 58.47 ENST00000389704.3
exosome component 8
chr8_+_48873479 57.83 ENST00000262105.2
minichromosome maintenance complex component 4
chr13_+_114238997 57.80 ENST00000538138.1
ENST00000375370.5
transcription factor Dp-1
chr4_-_77069573 57.33 ENST00000264883.3
nucleoporin 54kDa
chr9_+_106856831 57.20 ENST00000303219.8
ENST00000374787.3
structural maintenance of chromosomes 2
chr2_+_48010221 57.03 ENST00000234420.5
mutS homolog 6
chr7_+_26240776 56.71 ENST00000337620.4
chromobox homolog 3
chr8_+_128748466 56.20 ENST00000524013.1
ENST00000520751.1
v-myc avian myelocytomatosis viral oncogene homolog
chr5_+_177631523 55.12 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
heterogeneous nuclear ribonucleoprotein A/B
chr1_+_26798955 55.06 ENST00000361427.5
high mobility group nucleosomal binding domain 2
chr10_-_43892668 54.42 ENST00000544000.1
heterogeneous nuclear ribonucleoprotein F
chr2_+_48010312 54.28 ENST00000540021.1
mutS homolog 6
chr5_+_177631497 53.84 ENST00000358344.3
heterogeneous nuclear ribonucleoprotein A/B
chr10_-_17659234 53.08 ENST00000466335.1
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr12_-_57146095 53.05 ENST00000550770.1
ENST00000338193.6
primase, DNA, polypeptide 1 (49kDa)
chr19_-_50432782 52.69 ENST00000413454.1
ENST00000596437.1
ENST00000341114.3
ENST00000595948.1
nucleoporin 62kDa
interleukin 4 induced 1
chr12_+_69633372 51.26 ENST00000456847.3
ENST00000266679.8
cleavage and polyadenylation specific factor 6, 68kDa
chr2_+_27440229 51.21 ENST00000264705.4
ENST00000403525.1
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr12_+_4647950 51.14 ENST00000321524.7
ENST00000543041.1
ENST00000228843.9
ENST00000352618.4
ENST00000544927.1
RAD51 associated protein 1
chr10_+_14880157 50.21 ENST00000378372.3
heat shock 70kDa protein 14
chr12_-_57081940 50.01 ENST00000436399.2
prostaglandin E synthase 3 (cytosolic)
chr17_-_48474828 47.77 ENST00000576448.1
ENST00000225972.7
leucine rich repeat containing 59
chr1_-_33502528 47.12 ENST00000354858.6
adenylate kinase 2
chr17_+_30264014 47.04 ENST00000322652.5
ENST00000580398.1
SUZ12 polycomb repressive complex 2 subunit
chr22_+_35796108 46.90 ENST00000382011.5
ENST00000416905.1
minichromosome maintenance complex component 5
chr10_-_43892279 46.40 ENST00000443950.2
heterogeneous nuclear ribonucleoprotein F
chr4_+_57301896 46.26 ENST00000514888.1
ENST00000264221.2
ENST00000505164.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr7_-_26240357 46.26 ENST00000354667.4
ENST00000356674.7
heterogeneous nuclear ribonucleoprotein A2/B1
chr16_-_8962853 46.06 ENST00000565287.1
ENST00000311052.5
calcium regulated heat stable protein 1, 24kDa
chr19_-_48673580 45.74 ENST00000427526.2
ligase I, DNA, ATP-dependent
chr21_-_34960948 45.21 ENST00000453626.1
ENST00000303113.6
ENST00000432378.1
ENST00000303071.5
downstream neighbor of SON
chr21_-_34960930 45.10 ENST00000437395.1
downstream neighbor of SON
chr5_+_134094461 45.02 ENST00000452510.2
ENST00000354283.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr2_+_181845298 44.77 ENST00000410062.4
ubiquitin-conjugating enzyme E2E 3
chr1_-_197115818 43.79 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr2_+_216974020 42.77 ENST00000392132.2
ENST00000417391.1
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr19_-_1568057 42.61 ENST00000402693.4
ENST00000388824.6
mex-3 RNA binding family member D
chr22_+_19467261 42.61 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
cell division cycle 45
chr22_+_19419425 42.60 ENST00000333130.3
mitochondrial ribosomal protein L40
chr5_+_167913450 41.92 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chr1_+_33116743 41.64 ENST00000414241.3
ENST00000373493.5
retinoblastoma binding protein 4
chr3_+_157823609 41.42 ENST00000480820.1
arginine/serine-rich coiled-coil 1
chr6_-_18265050 41.25 ENST00000397239.3
DEK oncogene
chr15_-_64673665 41.23 ENST00000300035.4
KIAA0101
chr22_+_35796056 41.05 ENST00000216122.4
minichromosome maintenance complex component 5
chr8_-_124408652 40.96 ENST00000287394.5
ATPase family, AAA domain containing 2
chr10_+_62538089 40.34 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr3_+_128997798 40.31 ENST00000502878.2
ENST00000389735.3
ENST00000509551.1
ENST00000511665.1
5-hydroxymethylcytosine (hmC) binding, ES cell-specific
chr5_+_65222299 40.26 ENST00000284037.5
erbb2 interacting protein
chr14_-_45603657 39.91 ENST00000396062.3
FK506 binding protein 3, 25kDa
chr10_+_124913930 39.85 ENST00000368858.5
BUB3 mitotic checkpoint protein
chr22_+_35653445 39.76 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMG box domain containing 4
chr5_-_79950371 39.71 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
dihydrofolate reductase
chr1_-_8939265 39.67 ENST00000489867.1
enolase 1, (alpha)
chr5_+_72112418 39.55 ENST00000454282.1
transportin 1
chr1_+_43148625 39.51 ENST00000436427.1
Y box binding protein 1
chr5_+_61602055 39.39 ENST00000381103.2
kinesin heavy chain member 2A
chr15_-_85259294 39.33 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11 homolog A (S. cerevisiae)
chr1_-_33502441 39.08 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
adenylate kinase 2
chr1_+_91966656 38.91 ENST00000428239.1
ENST00000426137.1
cell division cycle 7
chr15_+_41624892 38.62 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
nucleolar and spindle associated protein 1
chr12_-_112856623 38.40 ENST00000551291.2
ribosomal protein L6
chr19_+_35645817 38.20 ENST00000423817.3
FXYD domain containing ion transport regulator 5
chr14_-_23426337 38.09 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS augmin-like complex, subunit 4
chr6_-_159065741 37.99 ENST00000367085.3
ENST00000367089.3
dynein, light chain, Tctex-type 1
chr14_-_23426322 37.86 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr1_+_156052354 37.81 ENST00000368301.2
lamin A/C
chr19_+_571277 37.61 ENST00000346916.4
ENST00000545507.2
basigin (Ok blood group)
chr11_+_125496124 37.43 ENST00000533778.2
ENST00000534070.1
checkpoint kinase 1
chr12_+_16064258 37.41 ENST00000524480.1
ENST00000531803.1
ENST00000532964.1
deoxyribose-phosphate aldolase (putative)
chr7_+_156931606 37.38 ENST00000348165.5
ubiquitin protein ligase E3C
chr8_-_103876965 37.31 ENST00000337198.5
antizyme inhibitor 1
chr9_+_127631399 37.15 ENST00000259477.6
actin related protein 2/3 complex, subunit 5-like
chr16_+_81040794 36.99 ENST00000439957.3
ENST00000393335.3
ENST00000428963.2
ENST00000564669.1
centromere protein N
chr16_+_29817841 36.92 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr3_-_185655795 36.82 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
transformer 2 beta homolog (Drosophila)
chrX_-_153707246 36.81 ENST00000407062.1
L antigen family, member 3
chr19_+_41257084 36.80 ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chr11_+_34073269 36.77 ENST00000389645.3
cell cycle associated protein 1
chr1_+_91966384 36.75 ENST00000430031.2
ENST00000234626.6
cell division cycle 7
chr10_-_17659357 36.49 ENST00000326961.6
ENST00000361271.3
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr9_-_35080013 36.37 ENST00000378643.3
Fanconi anemia, complementation group G
chr1_+_87170577 36.35 ENST00000482504.1
SH3-domain GRB2-like endophilin B1
chr10_+_95256356 36.27 ENST00000371485.3
centrosomal protein 55kDa
chr14_+_20937538 36.24 ENST00000361505.5
ENST00000553591.1
purine nucleoside phosphorylase
chr11_+_63953691 36.17 ENST00000543847.1
stress-induced-phosphoprotein 1
chr20_-_5100591 36.17 ENST00000379143.5
proliferating cell nuclear antigen
chr16_-_81040415 36.08 ENST00000564174.1
ENST00000562713.1
ENST00000570195.1
ENST00000565925.1
ENST00000565108.1
ENST00000565650.1
ENST00000486645.1
C-x(9)-C motif containing 2
chr15_+_48624300 35.98 ENST00000455976.2
ENST00000559540.1
deoxyuridine triphosphatase
chr10_+_62538248 35.80 ENST00000448257.2
cyclin-dependent kinase 1
chr7_-_72936531 35.54 ENST00000339594.4
bromodomain adjacent to zinc finger domain, 1B
chr14_-_23426270 35.49 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS augmin-like complex, subunit 4
chr4_+_113558272 35.10 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr15_-_85259384 35.01 ENST00000455959.3
SEC11 homolog A (S. cerevisiae)
chr7_-_73668692 34.97 ENST00000352131.3
ENST00000055077.3
replication factor C (activator 1) 2, 40kDa
chr19_+_35645618 34.81 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr12_-_56843161 34.69 ENST00000554616.1
ENST00000553532.1
ENST00000229201.4
timeless circadian clock
chr19_-_10530784 34.57 ENST00000593124.1
cell division cycle 37
chr15_-_85259330 34.50 ENST00000560266.1
SEC11 homolog A (S. cerevisiae)
chr4_-_39367949 34.49 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
replication factor C (activator 1) 1, 145kDa
chr1_+_212208919 34.37 ENST00000366991.4
ENST00000542077.1
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr16_+_29817399 34.36 ENST00000545521.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_-_17184605 34.29 ENST00000268717.5
COP9 signalosome subunit 3
chr12_+_69633407 34.13 ENST00000551516.1
cleavage and polyadenylation specific factor 6, 68kDa
chr12_+_66217911 33.89 ENST00000403681.2
high mobility group AT-hook 2
chr12_+_56360550 33.73 ENST00000266970.4
cyclin-dependent kinase 2
chr8_-_103876383 33.67 ENST00000347770.4
antizyme inhibitor 1
chr15_+_45926919 33.33 ENST00000561735.1
ENST00000260324.7
sulfide quinone reductase-like (yeast)
chr7_-_30544405 33.30 ENST00000409390.1
ENST00000409144.1
ENST00000005374.6
ENST00000409436.1
ENST00000275428.4
gamma-glutamylcyclotransferase
chr18_-_54318353 33.18 ENST00000590954.1
ENST00000540155.1
thioredoxin-like 1
chr18_-_34408693 33.14 ENST00000587382.1
ENST00000589049.1
ENST00000587129.1
tubulin polyglutamylase complex subunit 2
chr3_-_10028366 33.02 ENST00000429759.1
ER membrane protein complex subunit 3
chr3_+_127317066 32.98 ENST00000265056.7
minichromosome maintenance complex component 2
chr2_-_58468437 32.92 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
Fanconi anemia, complementation group L
chr4_-_170679024 32.81 ENST00000393381.2
chromosome 4 open reading frame 27
chr16_-_50402836 32.65 ENST00000394688.3
bromodomain containing 7
chr16_-_8962200 32.52 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
calcium regulated heat stable protein 1, 24kDa
chr2_-_215674374 32.51 ENST00000449967.2
ENST00000421162.1
ENST00000260947.4
BRCA1 associated RING domain 1
chrX_-_53449593 32.35 ENST00000375340.6
ENST00000322213.4
structural maintenance of chromosomes 1A
chr9_+_106856541 32.08 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
structural maintenance of chromosomes 2
chr12_+_104682496 32.06 ENST00000378070.4
thioredoxin reductase 1
chr5_+_138629417 32.05 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
matrin 3
chr12_-_76953573 31.92 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
oxysterol binding protein-like 8
chr16_-_50402690 31.83 ENST00000394689.2
bromodomain containing 7
chr14_-_24664776 31.79 ENST00000530468.1
ENST00000528010.1
ENST00000396854.4
ENST00000524835.1
ENST00000261789.4
ENST00000525592.1
transmembrane 9 superfamily member 1
chr14_-_24664540 31.79 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
transmembrane 9 superfamily member 1
chrX_-_20159934 31.78 ENST00000379593.1
ENST00000379607.5
eukaryotic translation initiation factor 1A, X-linked
chr2_-_27632390 31.76 ENST00000350803.4
ENST00000344034.4
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr8_-_95907423 31.41 ENST00000396133.3
ENST00000308108.4
cyclin E2
chr11_+_125495862 31.37 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
checkpoint kinase 1
chr17_-_28618948 31.20 ENST00000261714.6
bleomycin hydrolase
chr3_+_160117087 31.12 ENST00000357388.3
structural maintenance of chromosomes 4
chr5_-_79950775 30.98 ENST00000439211.2
dihydrofolate reductase
chr11_+_65686802 30.85 ENST00000376991.2
DR1-associated protein 1 (negative cofactor 2 alpha)
chr5_+_138629337 30.82 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
matrin 3
chr19_-_48673552 30.43 ENST00000536218.1
ENST00000596549.1
ligase I, DNA, ATP-dependent
chr3_+_133502877 30.39 ENST00000466490.2
signal recognition particle receptor, B subunit
chr14_+_97263641 30.26 ENST00000216639.3
vaccinia related kinase 1
chr7_+_100797726 30.22 ENST00000429457.1
adaptor-related protein complex 1, sigma 1 subunit
chr17_-_46178527 30.20 ENST00000393408.3
chromobox homolog 1
chr3_-_185542761 30.16 ENST00000457616.2
ENST00000346192.3
insulin-like growth factor 2 mRNA binding protein 2
chrX_-_153707545 30.08 ENST00000357360.4
L antigen family, member 3
chr7_+_100797678 29.99 ENST00000337619.5
adaptor-related protein complex 1, sigma 1 subunit
chr18_+_12948000 29.85 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1-like (S. cerevisiae)
chr11_+_65686728 29.83 ENST00000312515.2
ENST00000525501.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_+_572543 29.78 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
basigin (Ok blood group)
chr2_-_85641162 29.62 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
capping protein (actin filament), gelsolin-like
chr16_-_67693846 29.53 ENST00000602850.1
adrenocortical dysplasia homolog (mouse)
chr16_+_103816 29.52 ENST00000383018.3
ENST00000417493.1
small nuclear ribonucleoprotein 25kDa (U11/U12)

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F7_E2F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
66.2 198.7 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
51.4 154.1 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
49.2 196.9 GO:0019860 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) uracil metabolic process(GO:0019860)
48.4 241.8 GO:0010520 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
43.6 218.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
41.2 412.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
36.2 36.2 GO:0046102 inosine metabolic process(GO:0046102)
35.1 140.5 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
34.1 170.5 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
28.7 86.2 GO:0006172 ADP biosynthetic process(GO:0006172)
27.1 81.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
24.9 447.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
24.3 73.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
23.1 185.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
22.7 68.2 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
22.6 180.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
21.9 65.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
21.6 86.4 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
20.6 123.7 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
20.5 204.7 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
20.3 61.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
19.0 76.0 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
18.1 36.2 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
17.8 160.1 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
17.8 88.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
17.7 71.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
17.7 70.7 GO:0046452 dihydrofolate metabolic process(GO:0046452)
17.1 51.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
17.1 51.2 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
16.8 67.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
16.7 50.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
16.7 83.6 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
16.6 115.9 GO:0090204 protein localization to nuclear pore(GO:0090204)
16.1 48.4 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
16.0 112.2 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
14.6 58.5 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
14.5 144.8 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
14.2 56.9 GO:0032218 riboflavin transport(GO:0032218)
14.0 98.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
14.0 41.9 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
13.3 106.4 GO:0090166 Golgi disassembly(GO:0090166)
12.9 38.7 GO:1904430 negative regulation of t-circle formation(GO:1904430)
12.8 76.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
12.7 38.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
11.7 58.6 GO:0003164 His-Purkinje system development(GO:0003164)
11.5 92.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
11.5 34.6 GO:0052510 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
11.4 45.5 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
11.1 167.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
10.8 32.3 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
10.5 73.8 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
10.5 41.9 GO:0072719 cellular response to cisplatin(GO:0072719)
10.4 83.0 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
9.9 138.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
9.8 187.0 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
9.7 29.0 GO:0048627 myoblast development(GO:0048627)
9.7 77.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
9.5 66.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
9.5 266.6 GO:0006270 DNA replication initiation(GO:0006270)
9.3 289.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
9.2 27.7 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
9.2 27.5 GO:0045900 negative regulation of translational elongation(GO:0045900)
9.1 36.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
9.0 45.0 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
8.9 35.7 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
8.8 70.8 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
8.8 70.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
8.5 59.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
8.2 32.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
7.9 143.0 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
7.9 95.2 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
7.8 23.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
7.7 46.1 GO:0006021 inositol biosynthetic process(GO:0006021)
7.4 22.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
7.3 43.8 GO:0051661 maintenance of centrosome location(GO:0051661) spindle assembly involved in meiosis(GO:0090306)
7.2 21.7 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
7.2 57.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
7.1 42.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
7.0 63.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
7.0 20.9 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
6.9 34.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
6.8 13.6 GO:0048478 replication fork protection(GO:0048478)
6.8 54.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
6.7 40.4 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
6.7 26.9 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
6.7 40.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
6.6 39.8 GO:0043418 homocysteine catabolic process(GO:0043418)
6.6 26.3 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
6.5 32.5 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
6.5 32.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
6.4 77.2 GO:0008298 intracellular mRNA localization(GO:0008298)
6.4 25.5 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
6.3 38.0 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
6.3 18.8 GO:0071344 diphosphate metabolic process(GO:0071344)
6.2 137.3 GO:0006465 signal peptide processing(GO:0006465)
6.2 43.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
6.2 12.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
6.2 30.9 GO:0006740 NADPH regeneration(GO:0006740)
6.2 18.5 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
6.0 78.2 GO:0031507 heterochromatin assembly(GO:0031507)
5.9 35.4 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
5.6 78.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
5.6 16.9 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
5.6 122.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
5.5 22.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
5.5 16.6 GO:0006344 maintenance of chromatin silencing(GO:0006344)
5.5 16.6 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
5.5 21.9 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
5.5 27.4 GO:0042816 vitamin B6 metabolic process(GO:0042816)
5.4 21.8 GO:0015853 adenine transport(GO:0015853)
5.3 42.6 GO:2000252 negative regulation of feeding behavior(GO:2000252)
5.2 5.2 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
5.0 15.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
5.0 25.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
4.9 24.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
4.8 47.8 GO:0010265 SCF complex assembly(GO:0010265)
4.7 47.3 GO:0000733 DNA strand renaturation(GO:0000733)
4.7 37.7 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
4.7 37.2 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
4.6 18.6 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
4.6 46.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
4.6 18.5 GO:0072711 cellular response to hydroxyurea(GO:0072711)
4.5 185.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
4.5 27.1 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
4.5 13.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
4.5 9.0 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
4.5 67.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
4.4 44.0 GO:0001866 NK T cell proliferation(GO:0001866)
4.3 17.2 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
4.2 12.6 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
4.2 41.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
4.1 28.8 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
4.1 16.4 GO:0006177 GMP biosynthetic process(GO:0006177)
4.0 12.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
4.0 55.8 GO:0033260 nuclear DNA replication(GO:0033260)
3.9 55.2 GO:0046689 response to mercury ion(GO:0046689)
3.9 11.6 GO:0006624 vacuolar protein processing(GO:0006624)
3.9 11.6 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
3.8 7.7 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085)
3.8 22.7 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
3.7 15.0 GO:0007538 primary sex determination(GO:0007538)
3.7 71.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
3.7 26.1 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
3.7 14.9 GO:1903288 positive regulation of potassium ion import(GO:1903288)
3.7 3.7 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
3.7 92.8 GO:0006337 nucleosome disassembly(GO:0006337)
3.7 33.4 GO:0051660 establishment of centrosome localization(GO:0051660)
3.7 11.0 GO:0006106 fumarate metabolic process(GO:0006106)
3.6 10.9 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
3.6 43.0 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
3.6 21.5 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
3.6 46.5 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
3.6 32.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
3.6 32.1 GO:0001887 selenium compound metabolic process(GO:0001887)
3.5 10.6 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
3.5 28.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
3.5 10.5 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
3.5 10.4 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
3.5 24.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
3.5 10.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
3.4 51.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
3.4 13.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
3.3 3.3 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
3.3 19.7 GO:0007386 compartment pattern specification(GO:0007386)
3.3 13.1 GO:0035065 regulation of histone acetylation(GO:0035065)
3.2 13.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
3.2 19.5 GO:0051382 kinetochore assembly(GO:0051382)
3.2 48.1 GO:0061157 mRNA destabilization(GO:0061157)
3.2 9.6 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
3.2 9.6 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
3.2 9.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
3.2 12.6 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
3.2 252.3 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
3.1 56.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
3.1 9.4 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
3.1 28.1 GO:0070734 histone H3-K27 methylation(GO:0070734)
3.1 12.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
3.1 46.0 GO:0090168 Golgi reassembly(GO:0090168)
3.0 51.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
3.0 9.0 GO:0006059 hexitol metabolic process(GO:0006059)
3.0 14.9 GO:0006414 translational elongation(GO:0006414)
2.9 23.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
2.9 5.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
2.9 11.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
2.9 163.4 GO:0006378 mRNA polyadenylation(GO:0006378)
2.8 126.9 GO:0007080 mitotic metaphase plate congression(GO:0007080)
2.8 8.4 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
2.8 44.7 GO:0043248 proteasome assembly(GO:0043248)
2.8 19.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
2.8 44.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
2.7 8.2 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
2.6 15.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
2.5 39.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
2.5 41.9 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
2.4 97.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
2.4 94.9 GO:0006301 postreplication repair(GO:0006301)
2.4 7.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
2.3 14.0 GO:0008354 germ cell migration(GO:0008354)
2.3 7.0 GO:0042369 vitamin D catabolic process(GO:0042369)
2.3 15.8 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
2.2 11.2 GO:1902415 regulation of mRNA binding(GO:1902415) regulation of RNA binding(GO:1905214)
2.2 53.5 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
2.2 13.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
2.2 8.9 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
2.2 15.4 GO:0070933 histone H4 deacetylation(GO:0070933)
2.2 19.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
2.2 28.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
2.2 28.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
2.1 8.5 GO:0015791 polyol transport(GO:0015791)
2.1 10.5 GO:1904274 tricellular tight junction assembly(GO:1904274)
2.1 14.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
2.1 33.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
2.1 8.3 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
2.1 92.5 GO:0032392 DNA geometric change(GO:0032392)
2.1 194.8 GO:0051225 spindle assembly(GO:0051225)
2.0 134.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
2.0 16.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
2.0 26.1 GO:0071888 macrophage apoptotic process(GO:0071888)
2.0 14.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
2.0 143.8 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
2.0 6.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
2.0 58.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
1.9 23.2 GO:0070986 left/right axis specification(GO:0070986)
1.9 7.7 GO:0009956 radial pattern formation(GO:0009956)
1.9 3.8 GO:0040031 snRNA modification(GO:0040031)
1.9 34.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
1.9 5.7 GO:0002886 regulation of myeloid leukocyte mediated immunity(GO:0002886) regulation of leukocyte degranulation(GO:0043300)
1.9 9.5 GO:1902739 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
1.9 3.8 GO:0010040 response to iron(II) ion(GO:0010040)
1.8 3.7 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
1.8 12.8 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
1.8 21.9 GO:0070327 thyroid hormone transport(GO:0070327)
1.8 7.2 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
1.8 8.8 GO:0070383 DNA cytosine deamination(GO:0070383)
1.8 24.6 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
1.7 3.5 GO:0070295 renal water absorption(GO:0070295)
1.7 56.7 GO:0043687 post-translational protein modification(GO:0043687)
1.6 16.4 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
1.6 22.9 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.6 4.9 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
1.6 22.5 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.6 9.7 GO:0046323 regulation of glucose transport(GO:0010827) glucose import(GO:0046323) regulation of glucose import(GO:0046324)
1.6 51.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
1.6 14.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.6 6.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
1.6 10.9 GO:0035898 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
1.6 4.7 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
1.6 3.1 GO:0035608 protein deglutamylation(GO:0035608)
1.5 9.3 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.5 7.7 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
1.5 12.3 GO:0015846 polyamine transport(GO:0015846)
1.5 9.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
1.5 4.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
1.5 4.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
1.5 5.9 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
1.5 65.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
1.5 66.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
1.4 2.9 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.4 60.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.4 10.0 GO:0031929 TOR signaling(GO:0031929) regulation of TOR signaling(GO:0032006)
1.4 11.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
1.4 14.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
1.4 4.2 GO:1900133 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) positive regulation of eosinophil degranulation(GO:0043311) regulation of renin secretion into blood stream(GO:1900133) positive regulation of eosinophil activation(GO:1902568)
1.4 14.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.4 4.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
1.4 15.2 GO:0045116 protein neddylation(GO:0045116)
1.4 1.4 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.4 17.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.3 5.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
1.3 13.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.3 5.3 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
1.3 7.9 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
1.3 4.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
1.3 11.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.3 7.9 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
1.3 7.8 GO:0030421 defecation(GO:0030421)
1.3 6.5 GO:0006529 asparagine biosynthetic process(GO:0006529)
1.3 14.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
1.3 104.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.3 20.5 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
1.3 9.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.3 14.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.2 11.2 GO:0070208 protein heterotrimerization(GO:0070208)
1.2 6.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
1.2 9.9 GO:1901419 regulation of response to alcohol(GO:1901419)
1.2 8.6 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
1.2 3.7 GO:0001923 B-1 B cell differentiation(GO:0001923)
1.2 3.6 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
1.2 6.0 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
1.2 13.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
1.2 41.5 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
1.2 5.8 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
1.2 21.0 GO:0002021 response to dietary excess(GO:0002021)
1.2 3.5 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
1.2 8.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
1.1 8.0 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
1.1 5.7 GO:1903416 response to glycoside(GO:1903416)
1.1 41.0 GO:0035329 hippo signaling(GO:0035329)
1.1 158.0 GO:0043488 regulation of mRNA stability(GO:0043488)
1.1 19.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
1.1 1.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.1 5.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.1 18.9 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
1.1 13.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
1.1 28.6 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
1.1 4.4 GO:0007042 lysosomal lumen acidification(GO:0007042)
1.1 4.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
1.1 1.1 GO:0033277 abortive mitotic cell cycle(GO:0033277) negative regulation of growth hormone secretion(GO:0060125)
1.1 40.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
1.1 14.0 GO:0045008 depyrimidination(GO:0045008)
1.1 50.4 GO:0075733 intracellular transport of virus(GO:0075733)
1.1 43.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
1.1 16.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)
1.1 98.0 GO:0090114 COPII-coated vesicle budding(GO:0090114)
1.1 1.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
1.1 13.8 GO:0006449 regulation of translational termination(GO:0006449)
1.1 4.2 GO:0016584 nucleosome positioning(GO:0016584)
1.0 72.1 GO:0045454 cell redox homeostasis(GO:0045454)
1.0 3.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
1.0 5.2 GO:2000035 regulation of stem cell division(GO:2000035)
1.0 6.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.0 24.4 GO:0043968 histone H2A acetylation(GO:0043968)
1.0 8.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.0 7.9 GO:2000210 positive regulation of anoikis(GO:2000210)
1.0 4.9 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
1.0 3.9 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
1.0 13.7 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
1.0 15.5 GO:0009313 oligosaccharide catabolic process(GO:0009313)
1.0 4.8 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.9 13.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.9 5.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.9 96.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.9 4.4 GO:0070836 caveola assembly(GO:0070836)
0.9 4.4 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.9 8.7 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.9 6.9 GO:0032310 prostaglandin secretion(GO:0032310)
0.9 4.3 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.9 35.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.9 12.8 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.9 1.7 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.9 7.7 GO:0001825 blastocyst formation(GO:0001825)
0.8 49.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.8 12.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.8 3.3 GO:0043335 protein unfolding(GO:0043335)
0.8 4.1 GO:0021759 globus pallidus development(GO:0021759)
0.8 8.2 GO:1904667 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.8 12.3 GO:1903540 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.8 3.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.8 2.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.8 4.1 GO:0042659 regulation of cell fate specification(GO:0042659)
0.8 10.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.8 40.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.8 8.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.7 5.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.7 21.2 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.7 7.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.7 4.3 GO:1990791 amacrine cell differentiation(GO:0035881) dorsal root ganglion development(GO:1990791)
0.7 2.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.7 6.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.7 17.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.7 18.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.7 35.5 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.6 16.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.6 18.3 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.6 13.1 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.6 3.7 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.6 5.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.6 4.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.6 56.1 GO:0006334 nucleosome assembly(GO:0006334)
0.6 7.0 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.6 10.6 GO:0008228 opsonization(GO:0008228)
0.6 8.7 GO:0045109 intermediate filament organization(GO:0045109)
0.6 2.9 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.6 4.6 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.6 9.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.6 7.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.6 2.2 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.6 30.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.5 2.7 GO:0030047 actin modification(GO:0030047)
0.5 3.8 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.5 22.2 GO:0008333 endosome to lysosome transport(GO:0008333)
0.5 7.0 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.5 10.2 GO:0048246 macrophage chemotaxis(GO:0048246)
0.5 44.3 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.5 3.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.5 11.1 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.5 1.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.5 4.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.5 2.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.5 4.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.5 6.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.5 3.0 GO:2000146 negative regulation of cell motility(GO:2000146)
0.5 9.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.5 4.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.5 2.0 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 5.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.5 1.0 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.5 4.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.5 3.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.5 5.5 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.5 4.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.5 9.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.5 2.3 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.5 0.9 GO:1904874 positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.5 2.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.4 1.8 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.4 15.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.4 2.2 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.4 1.3 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4 6.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.4 11.4 GO:0030224 monocyte differentiation(GO:0030224)
0.4 14.4 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.4 12.7 GO:0007052 mitotic spindle organization(GO:0007052)
0.4 2.5 GO:0035803 egg coat formation(GO:0035803)
0.4 3.3 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.4 10.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 10.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.4 10.7 GO:0006401 RNA catabolic process(GO:0006401)
0.4 2.4 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.4 0.8 GO:0046856 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.4 6.4 GO:0002828 regulation of type 2 immune response(GO:0002828)
0.4 4.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4 17.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.3 5.9 GO:0007031 peroxisome organization(GO:0007031)
0.3 7.7 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.3 2.0 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 7.9 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.3 1.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.3 3.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 2.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.3 22.7 GO:0006413 translational initiation(GO:0006413)
0.3 2.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 3.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.3 8.6 GO:0046677 response to antibiotic(GO:0046677)
0.3 0.9 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.3 1.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 3.5 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 2.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.3 2.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 2.8 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.3 15.5 GO:0016925 protein sumoylation(GO:0016925)
0.3 20.2 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.3 8.9 GO:0014037 Schwann cell differentiation(GO:0014037)
0.3 1.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.3 1.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.2 1.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.2 5.3 GO:0010842 retina layer formation(GO:0010842)
0.2 1.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 14.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 14.2 GO:0006338 chromatin remodeling(GO:0006338)
0.2 4.0 GO:0006284 base-excision repair(GO:0006284)
0.2 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.8 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 0.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 4.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2 0.6 GO:0034398 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.2 0.8 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.2 4.7 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.2 2.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.2 0.2 GO:0072070 loop of Henle development(GO:0072070)
0.2 2.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.2 1.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 1.3 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.2 0.8 GO:0030238 male sex determination(GO:0030238)
0.2 6.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.2 1.9 GO:0019388 galactose catabolic process(GO:0019388)
0.2 1.5 GO:0034453 microtubule anchoring(GO:0034453)
0.2 1.7 GO:0042407 cristae formation(GO:0042407)
0.1 10.2 GO:0051963 regulation of synapse assembly(GO:0051963)
0.1 2.9 GO:0019079 viral genome replication(GO:0019079)
0.1 1.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.2 GO:0042117 monocyte activation(GO:0042117)
0.1 15.9 GO:0006457 protein folding(GO:0006457)
0.1 8.0 GO:0008033 tRNA processing(GO:0008033)
0.1 1.3 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.1 2.0 GO:0044804 nucleophagy(GO:0044804)
0.1 1.5 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.1 1.5 GO:0017038 protein import into nucleus(GO:0006606) protein import(GO:0017038) protein targeting to nucleus(GO:0044744) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 2.8 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.7 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.6 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 2.7 GO:0019835 cytolysis(GO:0019835)
0.1 0.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 2.4 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.2 GO:0045727 positive regulation of translation(GO:0045727)
0.1 0.2 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 2.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0 2.0 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.5 GO:0035412 regulation of catenin import into nucleus(GO:0035412)
0.0 0.7 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 2.6 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
98.8 395.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
88.3 353.1 GO:0032301 MutSalpha complex(GO:0032301)
48.2 626.5 GO:0042555 MCM complex(GO:0042555)
41.3 288.8 GO:0005663 DNA replication factor C complex(GO:0005663)
31.9 255.5 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
28.4 283.8 GO:0000796 condensin complex(GO:0000796)
27.1 81.4 GO:0018444 translation release factor complex(GO:0018444)
26.0 104.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
24.9 373.6 GO:0045120 pronucleus(GO:0045120)
22.6 67.7 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
21.0 125.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
20.2 80.9 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
19.7 137.6 GO:0016589 NURF complex(GO:0016589)
19.6 137.3 GO:0005787 signal peptidase complex(GO:0005787)
18.1 72.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
16.7 66.9 GO:0000811 GINS complex(GO:0000811)
16.7 283.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
16.6 66.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
15.9 127.6 GO:0034715 pICln-Sm protein complex(GO:0034715)
15.2 76.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
14.9 119.1 GO:0042382 paraspeckles(GO:0042382)
14.2 42.6 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
13.5 67.6 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
13.4 66.9 GO:0000408 EKC/KEOPS complex(GO:0000408)
13.1 65.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
11.1 66.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
10.4 20.8 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
10.3 93.0 GO:0005638 lamin filament(GO:0005638)
9.2 36.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
9.2 101.0 GO:0005688 U6 snRNP(GO:0005688)
8.6 34.6 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
8.6 60.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
8.6 42.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
8.2 16.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
8.2 65.5 GO:0001739 sex chromatin(GO:0001739)
7.9 39.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
7.8 54.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
7.6 22.9 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
7.5 126.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
7.4 29.5 GO:0001740 Barr body(GO:0001740)
7.0 70.1 GO:0042575 DNA polymerase complex(GO:0042575)
7.0 21.0 GO:0031523 Myb complex(GO:0031523)
6.9 27.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
6.7 53.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
6.5 78.5 GO:0090543 Flemming body(GO:0090543)
6.5 64.9 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
6.5 77.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
6.4 64.2 GO:0070187 telosome(GO:0070187)
6.3 82.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
6.2 43.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
5.8 29.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
5.7 39.9 GO:0036449 microtubule minus-end(GO:0036449)
5.5 49.7 GO:0070652 HAUS complex(GO:0070652)
5.2 78.5 GO:0005641 nuclear envelope lumen(GO:0005641)
5.2 57.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
5.2 25.8 GO:0071797 LUBAC complex(GO:0071797)
5.2 25.8 GO:0032021 NELF complex(GO:0032021)
5.0 15.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
5.0 54.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
4.8 14.5 GO:0031372 UBC13-MMS2 complex(GO:0031372)
4.8 19.2 GO:0044611 nuclear pore inner ring(GO:0044611)
4.8 23.8 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
4.7 37.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
4.7 14.1 GO:0031262 Ndc80 complex(GO:0031262)
4.7 131.2 GO:0035145 exon-exon junction complex(GO:0035145)
4.7 14.0 GO:0034680 integrin alpha1-beta1 complex(GO:0034665) integrin alpha3-beta1 complex(GO:0034667) integrin alpha8-beta1 complex(GO:0034678) integrin alpha10-beta1 complex(GO:0034680)
4.7 14.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
4.6 41.8 GO:0072546 ER membrane protein complex(GO:0072546)
4.6 9.1 GO:0071020 post-spliceosomal complex(GO:0071020)
4.5 40.7 GO:0032059 bleb(GO:0032059)
4.5 49.8 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
4.5 27.1 GO:0072589 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
4.5 44.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
4.4 35.1 GO:0031931 TORC1 complex(GO:0031931)
4.4 8.7 GO:0033186 CAF-1 complex(GO:0033186)
4.3 29.9 GO:0061700 GATOR2 complex(GO:0061700)
4.2 38.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
4.2 58.9 GO:0005662 DNA replication factor A complex(GO:0005662)
4.2 66.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
4.1 28.6 GO:0034709 methylosome(GO:0034709)
4.0 48.4 GO:0030008 TRAPP complex(GO:0030008)
4.0 28.0 GO:0005956 protein kinase CK2 complex(GO:0005956)
3.9 11.7 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
3.9 62.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
3.8 15.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
3.7 37.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
3.6 61.1 GO:0005686 U2 snRNP(GO:0005686)
3.5 10.6 GO:0005826 actomyosin contractile ring(GO:0005826)
3.4 299.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
3.4 129.7 GO:0000421 autophagosome membrane(GO:0000421)
3.4 13.6 GO:0031298 replication fork protection complex(GO:0031298)
3.4 37.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
3.4 30.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
3.3 66.5 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
3.3 13.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
3.3 118.5 GO:0090544 BAF-type complex(GO:0090544)
3.3 9.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
3.3 26.1 GO:0034719 SMN-Sm protein complex(GO:0034719)
3.2 22.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
3.1 40.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
3.0 82.2 GO:0002080 acrosomal membrane(GO:0002080)
3.0 121.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
3.0 27.0 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
3.0 8.9 GO:0005588 collagen type V trimer(GO:0005588)
2.9 14.7 GO:0000938 GARP complex(GO:0000938)
2.9 17.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
2.7 24.3 GO:0005721 pericentric heterochromatin(GO:0005721)
2.7 64.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
2.7 50.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
2.6 15.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
2.5 7.6 GO:0070939 Dsl1p complex(GO:0070939)
2.3 44.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
2.2 46.9 GO:0070822 Sin3-type complex(GO:0070822)
2.2 22.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
2.2 136.2 GO:0005637 nuclear inner membrane(GO:0005637)
2.2 37.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
2.2 4.4 GO:0035869 ciliary transition zone(GO:0035869)
2.0 14.3 GO:0000178 exosome (RNase complex)(GO:0000178)
2.0 11.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
2.0 181.2 GO:0005643 nuclear pore(GO:0005643)
2.0 27.8 GO:0070578 RISC-loading complex(GO:0070578)
2.0 5.9 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
1.9 13.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
1.9 11.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
1.8 170.5 GO:0070469 respiratory chain(GO:0070469)
1.8 5.3 GO:0009925 basal plasma membrane(GO:0009925)
1.8 12.4 GO:0016272 prefoldin complex(GO:0016272)
1.8 10.5 GO:0061689 tricellular tight junction(GO:0061689)
1.7 13.3 GO:0032389 MutLalpha complex(GO:0032389)
1.6 138.1 GO:0000502 proteasome complex(GO:0000502)
1.6 51.2 GO:0030057 desmosome(GO:0030057)
1.6 47.9 GO:0030686 90S preribosome(GO:0030686)
1.6 14.2 GO:0000439 core TFIIH complex(GO:0000439)
1.6 11.0 GO:0042788 polysomal ribosome(GO:0042788)
1.6 40.7 GO:0000118 histone deacetylase complex(GO:0000118)
1.6 70.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.5 74.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
1.5 4.6 GO:1990023 mitotic spindle midzone(GO:1990023)
1.5 36.1 GO:0005680 anaphase-promoting complex(GO:0005680)
1.5 7.4 GO:0032449 CBM complex(GO:0032449)
1.4 72.4 GO:0031430 M band(GO:0031430)
1.4 77.6 GO:0005876 spindle microtubule(GO:0005876)
1.4 4.1 GO:0044393 microspike(GO:0044393)
1.4 30.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
1.4 54.2 GO:0017053 transcriptional repressor complex(GO:0017053)
1.4 25.7 GO:0046930 pore complex(GO:0046930)
1.3 24.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.3 5.4 GO:0030891 VCB complex(GO:0030891)
1.3 9.3 GO:0005652 nuclear lamina(GO:0005652)
1.3 160.8 GO:0034399 nuclear periphery(GO:0034399)
1.3 13.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.3 35.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.3 6.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.3 33.8 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
1.3 3.9 GO:0030893 meiotic cohesin complex(GO:0030893)
1.3 8.9 GO:0010369 chromocenter(GO:0010369)
1.3 67.3 GO:0045171 intercellular bridge(GO:0045171)
1.2 5.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
1.2 14.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.2 57.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.2 7.2 GO:0042587 glycogen granule(GO:0042587)
1.2 72.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
1.2 125.9 GO:0016605 PML body(GO:0016605)
1.2 3.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
1.2 120.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.1 4.6 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
1.1 25.1 GO:0030992 intraciliary transport particle B(GO:0030992)
1.1 4.3 GO:0036021 endolysosome lumen(GO:0036021)
1.1 20.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.1 10.8 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.1 13.9 GO:0031088 platelet dense granule membrane(GO:0031088)
1.0 39.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.0 66.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
1.0 22.6 GO:0015935 small ribosomal subunit(GO:0015935)
1.0 11.6 GO:0044754 autolysosome(GO:0044754)
0.9 10.3 GO:0005614 interstitial matrix(GO:0005614)
0.9 2.8 GO:0001652 granular component(GO:0001652)
0.9 4.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.9 0.9 GO:0032302 MutSbeta complex(GO:0032302)
0.9 37.2 GO:0016235 aggresome(GO:0016235)
0.8 125.2 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.8 58.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.8 12.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.8 251.5 GO:0016607 nuclear speck(GO:0016607)
0.8 8.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.8 200.5 GO:0000790 nuclear chromatin(GO:0000790)
0.8 1.6 GO:1990075 periciliary membrane compartment(GO:1990075)
0.8 10.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.8 59.6 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.8 52.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.8 81.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.8 35.9 GO:0008180 COP9 signalosome(GO:0008180)
0.7 7.4 GO:0044327 dendritic spine head(GO:0044327)
0.7 9.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.7 4.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.7 4.2 GO:0031143 pseudopodium(GO:0031143)
0.7 11.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.7 12.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.7 2.0 GO:0031417 NatC complex(GO:0031417)
0.6 74.8 GO:0000785 chromatin(GO:0000785)
0.6 78.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.6 15.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.6 10.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.6 76.2 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.6 25.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.6 1.7 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5 37.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.5 11.4 GO:0031264 death-inducing signaling complex(GO:0031264)
0.5 21.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.5 3.3 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.5 16.5 GO:0005681 spliceosomal complex(GO:0005681)
0.4 4.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 3.7 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.4 29.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.4 2.4 GO:0032039 integrator complex(GO:0032039)
0.4 5.4 GO:0030904 retromer complex(GO:0030904)
0.4 2.6 GO:0030126 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.3 10.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 37.6 GO:0035579 specific granule membrane(GO:0035579)
0.3 1.3 GO:0055037 recycling endosome(GO:0055037)
0.3 12.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 89.5 GO:0005635 nuclear envelope(GO:0005635)
0.3 92.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 3.8 GO:0031209 SCAR complex(GO:0031209)
0.3 9.2 GO:0005840 ribosome(GO:0005840)
0.3 6.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2 1.0 GO:0005915 zonula adherens(GO:0005915)
0.2 16.7 GO:0043195 terminal bouton(GO:0043195)
0.2 11.9 GO:0005811 lipid particle(GO:0005811)
0.2 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 0.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 7.2 GO:0005770 late endosome(GO:0005770)
0.2 44.8 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.2 8.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 19.9 GO:0005874 microtubule(GO:0005874)
0.2 15.7 GO:0001650 fibrillar center(GO:0001650)
0.2 8.2 GO:0030496 midbody(GO:0030496)
0.2 1.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 2.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 43.6 GO:0005925 focal adhesion(GO:0005925)
0.1 2.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 1.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 12.6 GO:0045177 apical part of cell(GO:0045177)
0.0 3.1 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
98.8 395.3 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
88.3 353.1 GO:0032143 single thymine insertion binding(GO:0032143)
51.4 154.1 GO:0004797 thymidine kinase activity(GO:0004797)
50.0 199.9 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
36.9 331.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
36.1 252.7 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
34.9 174.4 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
25.9 181.3 GO:0050733 RS domain binding(GO:0050733)
22.2 311.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
20.3 61.0 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
19.3 57.9 GO:0005047 signal recognition particle binding(GO:0005047)
18.2 109.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
18.2 72.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
17.3 104.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
17.1 51.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
17.1 51.2 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
16.3 81.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
15.1 45.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
14.2 56.9 GO:0032217 riboflavin transporter activity(GO:0032217)
14.0 41.9 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
12.8 115.3 GO:1990226 histone methyltransferase binding(GO:1990226)
12.8 76.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
12.4 37.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
12.0 36.0 GO:0004170 dUTP diphosphatase activity(GO:0004170)
11.9 47.4 GO:0036033 mediator complex binding(GO:0036033)
11.8 35.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
11.2 503.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
11.1 66.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
10.9 141.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
10.7 32.1 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
10.1 71.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
10.0 70.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
10.0 29.9 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
9.6 9.6 GO:0004137 deoxycytidine kinase activity(GO:0004137)
9.4 273.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
9.2 46.1 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
9.1 72.9 GO:1990446 U1 snRNP binding(GO:1990446)
8.8 35.4 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
8.3 66.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
8.2 49.0 GO:0036310 annealing helicase activity(GO:0036310)
7.8 86.0 GO:0004017 adenylate kinase activity(GO:0004017)
7.8 23.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
7.8 163.9 GO:0035173 histone kinase activity(GO:0035173)
7.8 318.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
7.6 60.4 GO:0005497 androgen binding(GO:0005497)
7.4 111.6 GO:0003678 DNA helicase activity(GO:0003678)
7.4 22.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
6.5 19.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
6.5 58.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
6.5 26.0 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
6.3 25.4 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
6.3 18.8 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
6.2 6.2 GO:0051731 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
6.1 36.4 GO:0017091 AU-rich element binding(GO:0017091)
5.9 11.7 GO:0043398 HLH domain binding(GO:0043398)
5.9 17.6 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
5.8 23.3 GO:0016887 ATPase activity(GO:0016887)
5.7 17.0 GO:0030984 kininogen binding(GO:0030984)
5.6 56.4 GO:0042731 PH domain binding(GO:0042731)
5.5 16.6 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
5.3 147.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
5.3 168.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
5.0 114.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
4.9 19.7 GO:0004074 biliverdin reductase activity(GO:0004074)
4.9 9.8 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
4.7 33.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791) protein-disulfide reductase activity(GO:0047134)
4.7 18.8 GO:0004427 inorganic diphosphatase activity(GO:0004427)
4.7 42.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
4.7 14.0 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
4.7 14.0 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
4.6 9.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
4.6 50.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
4.5 13.6 GO:0002060 purine nucleobase binding(GO:0002060)
4.5 22.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
4.5 27.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
4.5 27.0 GO:0043532 angiostatin binding(GO:0043532)
4.4 31.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
4.3 17.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
4.3 42.8 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
4.2 185.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
4.2 42.0 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
4.1 16.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
4.1 8.2 GO:0070990 snRNP binding(GO:0070990)
4.1 28.4 GO:0030620 U2 snRNA binding(GO:0030620)
4.0 27.7 GO:0050815 phosphoserine binding(GO:0050815)
3.9 78.9 GO:0005537 mannose binding(GO:0005537)
3.9 11.7 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
3.9 23.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
3.9 46.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
3.7 37.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
3.6 10.9 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
3.6 17.9 GO:0046790 virion binding(GO:0046790)
3.6 7.2 GO:0031177 phosphopantetheine binding(GO:0031177)
3.6 10.7 GO:0017130 poly(C) RNA binding(GO:0017130)
3.6 100.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
3.6 88.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
3.6 10.7 GO:0033149 FFAT motif binding(GO:0033149)
3.5 10.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
3.4 13.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
3.4 43.7 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
3.3 9.9 GO:0034511 U3 snoRNA binding(GO:0034511)
3.2 63.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
3.2 28.4 GO:0070883 pre-miRNA binding(GO:0070883)
3.1 62.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
3.0 63.9 GO:0000339 RNA cap binding(GO:0000339)
3.0 57.8 GO:0032794 GTPase activating protein binding(GO:0032794)
3.0 54.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
3.0 11.9 GO:0043515 kinetochore binding(GO:0043515)
3.0 137.4 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
3.0 11.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
2.9 14.4 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
2.9 11.5 GO:0055077 gap junction hemi-channel activity(GO:0055077)
2.9 145.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
2.8 8.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
2.8 14.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
2.8 11.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
2.8 14.0 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
2.8 19.6 GO:0001849 complement component C1q binding(GO:0001849)
2.8 11.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
2.8 13.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
2.7 21.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
2.7 143.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
2.6 13.2 GO:0061665 SUMO ligase activity(GO:0061665)
2.6 47.3 GO:0043274 phospholipase binding(GO:0043274)
2.6 15.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
2.6 153.9 GO:0070888 E-box binding(GO:0070888)
2.6 43.6 GO:0070182 DNA polymerase binding(GO:0070182)
2.5 50.2 GO:0004532 exoribonuclease activity(GO:0004532)
2.5 234.3 GO:0003727 single-stranded RNA binding(GO:0003727)
2.5 77.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
2.5 17.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
2.4 39.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
2.4 21.8 GO:0015288 porin activity(GO:0015288)
2.4 14.2 GO:0030957 Tat protein binding(GO:0030957)
2.4 11.9 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
2.4 7.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
2.3 186.1 GO:0004386 helicase activity(GO:0004386)
2.3 9.0 GO:0004335 galactokinase activity(GO:0004335)
2.2 40.3 GO:0008301 DNA binding, bending(GO:0008301)
2.2 24.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.2 15.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.1 323.9 GO:0042393 histone binding(GO:0042393)
2.1 56.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
2.1 6.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
2.1 22.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
2.1 16.5 GO:0019237 centromeric DNA binding(GO:0019237)
2.0 8.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.0 6.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
2.0 30.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
1.9 7.8 GO:0038025 reelin receptor activity(GO:0038025)
1.9 22.9 GO:0038132 neuregulin binding(GO:0038132)
1.9 37.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.8 24.0 GO:0031491 nucleosome binding(GO:0031491)
1.8 7.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
1.8 52.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.8 12.7 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.8 5.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.8 7.2 GO:0004348 glucosylceramidase activity(GO:0004348)
1.8 16.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.7 6.9 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
1.7 10.2 GO:0000182 rDNA binding(GO:0000182)
1.6 3.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
1.6 16.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
1.6 19.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.6 6.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.6 7.9 GO:0015140 malate transmembrane transporter activity(GO:0015140)
1.6 18.9 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
1.6 4.7 GO:0035033 histone deacetylase regulator activity(GO:0035033)
1.6 84.2 GO:0050681 androgen receptor binding(GO:0050681)
1.6 17.1 GO:0039706 co-receptor binding(GO:0039706)
1.5 13.7 GO:0031386 protein tag(GO:0031386)
1.5 25.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
1.5 16.2 GO:0019206 nucleoside kinase activity(GO:0019206)
1.5 45.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
1.5 10.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.4 109.3 GO:0003697 single-stranded DNA binding(GO:0003697)
1.4 14.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.4 56.8 GO:0030544 Hsp70 protein binding(GO:0030544)
1.4 14.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
1.4 7.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
1.4 65.3 GO:0003725 double-stranded RNA binding(GO:0003725)
1.4 10.9 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.4 43.3 GO:0031369 translation initiation factor binding(GO:0031369)
1.3 29.5 GO:0008483 transaminase activity(GO:0008483)
1.3 15.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
1.3 14.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
1.3 140.9 GO:0051082 unfolded protein binding(GO:0051082)
1.3 268.7 GO:0003735 structural constituent of ribosome(GO:0003735)
1.3 7.8 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.3 6.5 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
1.3 20.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.3 3.8 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
1.3 3.8 GO:0051538 iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
1.2 5.0 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
1.2 32.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
1.2 9.5 GO:0045545 syndecan binding(GO:0045545)
1.2 3.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
1.1 4.6 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
1.1 6.8 GO:0061133 endopeptidase activator activity(GO:0061133)
1.1 2.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.1 138.6 GO:0032182 ubiquitin-like protein binding(GO:0032182)
1.1 18.1 GO:0048487 beta-tubulin binding(GO:0048487)
1.1 83.7 GO:0008565 protein transporter activity(GO:0008565)
1.1 7.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.1 6.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.1 7.4 GO:0008201 heparin binding(GO:0008201)
1.1 10.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
1.1 3.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
1.0 8.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.0 13.8 GO:0003993 acid phosphatase activity(GO:0003993)
1.0 3.9 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
1.0 44.9 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
1.0 5.8 GO:0017018 myosin phosphatase activity(GO:0017018)
0.9 2.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.9 29.2 GO:0042605 peptide antigen binding(GO:0042605)
0.9 19.2 GO:0070064 proline-rich region binding(GO:0070064)
0.9 14.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.9 4.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.9 5.1 GO:0000287 magnesium ion binding(GO:0000287)
0.9 6.0 GO:0004046 aminoacylase activity(GO:0004046)
0.9 11.1 GO:0031996 thioesterase binding(GO:0031996)
0.8 2.5 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.8 3.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.8 9.0 GO:0070628 proteasome binding(GO:0070628)
0.8 186.7 GO:0051015 actin filament binding(GO:0051015)
0.8 10.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.8 31.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.8 6.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.8 19.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.8 39.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.8 23.3 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.7 16.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.7 7.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.7 130.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.7 6.5 GO:0003680 AT DNA binding(GO:0003680)
0.7 7.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.7 30.2 GO:0042169 SH2 domain binding(GO:0042169)
0.7 9.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.7 4.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.7 3.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.7 25.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.7 13.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.7 36.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.7 9.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.7 4.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.7 4.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.6 24.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.6 1.9 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.6 1.8 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.6 15.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.6 5.9 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.6 38.8 GO:0051287 NAD binding(GO:0051287)
0.6 1.7 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.6 6.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5 4.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.5 4.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.5 10.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.5 80.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.5 41.1 GO:0003777 microtubule motor activity(GO:0003777)
0.5 141.0 GO:0045296 cadherin binding(GO:0045296)
0.5 13.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 3.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5 22.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.5 2.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.5 14.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.4 36.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.4 6.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.4 6.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 362.5 GO:0003723 RNA binding(GO:0003723)
0.4 28.8 GO:0032947 protein complex scaffold(GO:0032947)
0.4 4.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.4 11.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.4 1.9 GO:0030151 molybdenum ion binding(GO:0030151)
0.4 8.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 3.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.3 3.5 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3 10.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.3 10.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 2.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 4.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.3 9.9 GO:0008009 chemokine activity(GO:0008009)
0.3 2.0 GO:0008199 ferric iron binding(GO:0008199)
0.3 7.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 2.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.3 2.5 GO:0032190 acrosin binding(GO:0032190)
0.3 4.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 3.9 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.3 1.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.2 4.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 7.7 GO:0001972 retinoic acid binding(GO:0001972)
0.2 3.1 GO:0070410 co-SMAD binding(GO:0070410)
0.2 9.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 9.1 GO:0043621 protein self-association(GO:0043621)
0.2 2.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 0.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.2 5.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 3.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 41.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 39.1 GO:0003924 GTPase activity(GO:0003924)
0.1 0.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 9.2 GO:0051117 ATPase binding(GO:0051117)
0.1 36.6 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 7.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 1.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 7.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 0.8 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 2.3 GO:0005109 frizzled binding(GO:0005109)
0.1 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.8 GO:0015485 cholesterol binding(GO:0015485)
0.1 7.4 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 1.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.1 GO:0044877 macromolecular complex binding(GO:0044877)
0.1 0.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 3.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 5.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 4.2 GO:0016301 kinase activity(GO:0016301)
0.0 0.9 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 1.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
12.2 1303.2 PID E2F PATHWAY E2F transcription factor network
12.1 302.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
8.9 544.3 PID ATR PATHWAY ATR signaling pathway
6.1 98.2 PID FANCONI PATHWAY Fanconi anemia pathway
3.9 239.1 PID AURORA B PATHWAY Aurora B signaling
3.9 34.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
3.4 115.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
2.7 258.2 PID TELOMERASE PATHWAY Regulation of Telomerase
2.6 96.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
2.4 251.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
2.3 51.8 PID ATM PATHWAY ATM pathway
2.0 87.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
2.0 51.7 PID BARD1 PATHWAY BARD1 signaling events
1.7 102.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
1.7 290.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
1.7 46.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
1.6 31.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
1.6 91.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
1.6 28.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
1.6 103.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
1.5 63.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.5 37.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.5 16.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.4 133.8 PID CMYB PATHWAY C-MYB transcription factor network
1.4 4.2 ST GA12 PATHWAY G alpha 12 Pathway
1.3 52.0 PID PLK1 PATHWAY PLK1 signaling events
1.3 22.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.2 23.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
1.2 37.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
1.2 7.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
1.1 9.8 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.9 49.4 PID LKB1 PATHWAY LKB1 signaling events
0.8 8.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.8 20.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.8 26.6 PID IL3 PATHWAY IL3-mediated signaling events
0.8 32.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.7 7.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.6 4.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.6 8.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 8.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.5 16.9 PID ALK1 PATHWAY ALK1 signaling events
0.5 22.8 PID ARF6 PATHWAY Arf6 signaling events
0.5 27.9 PID P73PATHWAY p73 transcription factor network
0.5 28.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 34.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.5 2.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.5 8.9 PID FAS PATHWAY FAS (CD95) signaling pathway
0.5 14.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.4 2.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.4 24.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.4 11.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 4.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.3 17.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.3 5.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 7.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 3.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 1.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 3.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 3.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 3.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 7.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 4.8 PID NOTCH PATHWAY Notch signaling pathway
0.1 2.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.3 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
45.2 723.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
23.8 356.7 REACTOME POL SWITCHING Genes involved in Polymerase switching
21.5 516.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
18.8 150.1 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
15.2 242.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
11.2 359.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
10.5 209.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
10.0 190.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
9.7 357.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
8.6 146.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
8.5 144.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
7.8 241.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
7.7 130.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
7.1 85.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
6.5 26.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
6.3 196.4 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
6.0 36.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
6.0 144.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
5.4 315.5 REACTOME G1 PHASE Genes involved in G1 Phase
4.8 566.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
4.7 65.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
4.3 68.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
4.2 75.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
4.2 50.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
3.6 129.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
3.6 135.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
3.5 60.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
3.5 79.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
3.4 60.7 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
3.1 87.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
3.1 25.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
3.0 83.5 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
2.9 61.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
2.9 117.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
2.8 42.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
2.7 127.4 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
2.6 13.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
2.5 35.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
2.4 65.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
2.4 47.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
2.3 88.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
2.2 51.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
2.2 98.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
2.2 165.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
2.1 10.7 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
2.1 72.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
2.1 174.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
2.0 154.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
2.0 336.5 REACTOME TRANSLATION Genes involved in Translation
2.0 35.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
2.0 42.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
1.9 7.8 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
1.9 42.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.9 40.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.8 20.3 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
1.8 56.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
1.8 12.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
1.7 15.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.7 34.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.7 51.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.7 148.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
1.6 244.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.6 31.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.6 23.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
1.5 39.4 REACTOME KINESINS Genes involved in Kinesins
1.5 72.4 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
1.5 38.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
1.4 12.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.3 10.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
1.2 18.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
1.2 23.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
1.2 19.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.1 53.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.1 9.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.1 35.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.0 35.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
1.0 21.9 REACTOME METABOLISM OF NUCLEOTIDES Genes involved in Metabolism of nucleotides
0.9 43.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.8 35.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.7 4.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.7 3.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.7 41.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.7 12.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.7 17.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.7 18.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.7 8.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 14.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6 6.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.5 4.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.5 7.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.5 8.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.5 11.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.5 7.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.4 7.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.4 2.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.4 17.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.4 6.6 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.4 11.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 11.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 7.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.3 37.4 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.3 17.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 3.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.3 6.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 5.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.3 3.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 6.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 5.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 3.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 6.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 3.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 2.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 7.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 4.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.5 REACTOME OPSINS Genes involved in Opsins
0.1 1.3 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 3.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.9 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 1.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway