Project
averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for E2F7_E2F1
Z-value: 4.92
Motif logo
Transcription factors associated with E2F7_E2F1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
E2F7
|
ENSG00000165891.11 | E2F transcription factor 7 |
|
E2F1
|
ENSG00000101412.9 | E2F transcription factor 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| E2F1 | hg19_v2_chr20_-_32274179_32274213 | 0.73 | 1.5e-37 | Click! |
Activity profile of E2F7_E2F1 motif
Sorted Z-values of E2F7_E2F1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of E2F7_E2F1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 66.2 | 198.7 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 51.4 | 154.1 | GO:0046125 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 49.2 | 196.9 | GO:0019860 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) uracil metabolic process(GO:0019860) |
| 48.4 | 241.8 | GO:0010520 | meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520) |
| 43.6 | 218.2 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 41.2 | 412.0 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 36.2 | 36.2 | GO:0046102 | inosine metabolic process(GO:0046102) |
| 35.1 | 140.5 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 34.1 | 170.5 | GO:1904636 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 28.7 | 86.2 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 27.1 | 81.4 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 24.9 | 447.5 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 24.3 | 73.0 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 23.1 | 185.2 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 22.7 | 68.2 | GO:0060381 | regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744) |
| 22.6 | 180.7 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 21.9 | 65.6 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 21.6 | 86.4 | GO:0046100 | hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) |
| 20.6 | 123.7 | GO:0072131 | kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133) |
| 20.5 | 204.7 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 20.3 | 61.0 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 19.0 | 76.0 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 18.1 | 36.2 | GO:1902990 | mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
| 17.8 | 160.1 | GO:0009113 | purine nucleobase biosynthetic process(GO:0009113) |
| 17.8 | 88.9 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 17.7 | 71.0 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 17.7 | 70.7 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 17.1 | 51.3 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 17.1 | 51.2 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 16.8 | 67.1 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 16.7 | 50.2 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 16.7 | 83.6 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
| 16.6 | 115.9 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 16.1 | 48.4 | GO:0070512 | regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512) |
| 16.0 | 112.2 | GO:0043570 | maintenance of DNA repeat elements(GO:0043570) |
| 14.6 | 58.5 | GO:0034476 | U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) |
| 14.5 | 144.8 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 14.2 | 56.9 | GO:0032218 | riboflavin transport(GO:0032218) |
| 14.0 | 98.0 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 14.0 | 41.9 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 13.3 | 106.4 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 12.9 | 38.7 | GO:1904430 | negative regulation of t-circle formation(GO:1904430) |
| 12.8 | 76.7 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 12.7 | 38.2 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 11.7 | 58.6 | GO:0003164 | His-Purkinje system development(GO:0003164) |
| 11.5 | 92.3 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 11.5 | 34.6 | GO:0052510 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) |
| 11.4 | 45.5 | GO:1903436 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 11.1 | 167.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 10.8 | 32.3 | GO:0072402 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 10.5 | 73.8 | GO:1904688 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 10.5 | 41.9 | GO:0072719 | cellular response to cisplatin(GO:0072719) |
| 10.4 | 83.0 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 9.9 | 138.0 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 9.8 | 187.0 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 9.7 | 29.0 | GO:0048627 | myoblast development(GO:0048627) |
| 9.7 | 77.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 9.5 | 66.7 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 9.5 | 266.6 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 9.3 | 289.6 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 9.2 | 27.7 | GO:1902309 | regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 9.2 | 27.5 | GO:0045900 | negative regulation of translational elongation(GO:0045900) |
| 9.1 | 36.4 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 9.0 | 45.0 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 8.9 | 35.7 | GO:0036496 | regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) |
| 8.8 | 70.8 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 8.8 | 70.3 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 8.5 | 59.8 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 8.2 | 32.6 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 7.9 | 143.0 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 7.9 | 95.2 | GO:0046831 | regulation of RNA export from nucleus(GO:0046831) |
| 7.8 | 23.4 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 7.7 | 46.1 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 7.4 | 22.1 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 7.3 | 43.8 | GO:0051661 | maintenance of centrosome location(GO:0051661) spindle assembly involved in meiosis(GO:0090306) |
| 7.2 | 21.7 | GO:1990922 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 7.2 | 57.8 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 7.1 | 42.8 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 7.0 | 63.3 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 7.0 | 20.9 | GO:0097068 | response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386) |
| 6.9 | 34.4 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 6.8 | 13.6 | GO:0048478 | replication fork protection(GO:0048478) |
| 6.8 | 54.2 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 6.7 | 40.4 | GO:0044789 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 6.7 | 26.9 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 6.7 | 40.3 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 6.6 | 39.8 | GO:0043418 | homocysteine catabolic process(GO:0043418) |
| 6.6 | 26.3 | GO:0071373 | cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373) |
| 6.5 | 32.5 | GO:0085020 | protein K6-linked ubiquitination(GO:0085020) |
| 6.5 | 32.3 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 6.4 | 77.2 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 6.4 | 25.5 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 6.3 | 38.0 | GO:0019060 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 6.3 | 18.8 | GO:0071344 | diphosphate metabolic process(GO:0071344) |
| 6.2 | 137.3 | GO:0006465 | signal peptide processing(GO:0006465) |
| 6.2 | 43.5 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 6.2 | 12.4 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 6.2 | 30.9 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 6.2 | 18.5 | GO:1902499 | positive regulation of protein autoubiquitination(GO:1902499) |
| 6.0 | 78.2 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 5.9 | 35.4 | GO:0017187 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 5.6 | 78.8 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 5.6 | 16.9 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 5.6 | 122.5 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 5.5 | 22.2 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 5.5 | 16.6 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 5.5 | 16.6 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 5.5 | 21.9 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 5.5 | 27.4 | GO:0042816 | vitamin B6 metabolic process(GO:0042816) |
| 5.4 | 21.8 | GO:0015853 | adenine transport(GO:0015853) |
| 5.3 | 42.6 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
| 5.2 | 5.2 | GO:0007068 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 5.0 | 15.1 | GO:0000412 | histone peptidyl-prolyl isomerization(GO:0000412) |
| 5.0 | 25.1 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 4.9 | 24.5 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 4.8 | 47.8 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 4.7 | 47.3 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 4.7 | 37.7 | GO:0032057 | negative regulation of translational initiation in response to stress(GO:0032057) |
| 4.7 | 37.2 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 4.6 | 18.6 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 4.6 | 46.4 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 4.6 | 18.5 | GO:0072711 | cellular response to hydroxyurea(GO:0072711) |
| 4.5 | 185.1 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 4.5 | 27.1 | GO:1902510 | regulation of apoptotic DNA fragmentation(GO:1902510) |
| 4.5 | 13.5 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 4.5 | 9.0 | GO:0070638 | nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) |
| 4.5 | 67.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 4.4 | 44.0 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 4.3 | 17.2 | GO:1903803 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 4.2 | 12.6 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
| 4.2 | 41.9 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 4.1 | 28.8 | GO:0097033 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 4.1 | 16.4 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 4.0 | 12.1 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 4.0 | 55.8 | GO:0033260 | nuclear DNA replication(GO:0033260) |
| 3.9 | 55.2 | GO:0046689 | response to mercury ion(GO:0046689) |
| 3.9 | 11.6 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 3.9 | 11.6 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 3.8 | 7.7 | GO:0061085 | regulation of histone H3-K27 methylation(GO:0061085) |
| 3.8 | 22.7 | GO:2000371 | regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
| 3.7 | 15.0 | GO:0007538 | primary sex determination(GO:0007538) |
| 3.7 | 71.1 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 3.7 | 26.1 | GO:0009407 | toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487) |
| 3.7 | 14.9 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
| 3.7 | 3.7 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 3.7 | 92.8 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 3.7 | 33.4 | GO:0051660 | establishment of centrosome localization(GO:0051660) |
| 3.7 | 11.0 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 3.6 | 10.9 | GO:0032055 | negative regulation of translation in response to stress(GO:0032055) |
| 3.6 | 43.0 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 3.6 | 21.5 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 3.6 | 46.5 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 3.6 | 32.1 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 3.6 | 32.1 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 3.5 | 10.6 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 3.5 | 28.0 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 3.5 | 10.5 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 3.5 | 10.4 | GO:0018262 | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262) |
| 3.5 | 24.3 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 3.5 | 10.4 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 3.4 | 51.7 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 3.4 | 13.7 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 3.3 | 3.3 | GO:0072053 | renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) |
| 3.3 | 19.7 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 3.3 | 13.1 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
| 3.2 | 13.0 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 3.2 | 19.5 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 3.2 | 48.1 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 3.2 | 9.6 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 3.2 | 9.6 | GO:0009157 | deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) |
| 3.2 | 9.5 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 3.2 | 12.6 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 3.2 | 252.3 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 3.1 | 56.6 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 3.1 | 9.4 | GO:0000354 | cis assembly of pre-catalytic spliceosome(GO:0000354) |
| 3.1 | 28.1 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 3.1 | 12.3 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 3.1 | 46.0 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 3.0 | 51.4 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 3.0 | 9.0 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 3.0 | 14.9 | GO:0006414 | translational elongation(GO:0006414) |
| 2.9 | 23.4 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 2.9 | 5.8 | GO:0032922 | circadian regulation of gene expression(GO:0032922) |
| 2.9 | 11.5 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 2.9 | 163.4 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
| 2.8 | 126.9 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 2.8 | 8.4 | GO:0031587 | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) |
| 2.8 | 44.7 | GO:0043248 | proteasome assembly(GO:0043248) |
| 2.8 | 19.5 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056) |
| 2.8 | 44.5 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 2.7 | 8.2 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 2.6 | 15.6 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 2.5 | 39.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 2.5 | 41.9 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 2.4 | 97.7 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 2.4 | 94.9 | GO:0006301 | postreplication repair(GO:0006301) |
| 2.4 | 7.1 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 2.3 | 14.0 | GO:0008354 | germ cell migration(GO:0008354) |
| 2.3 | 7.0 | GO:0042369 | vitamin D catabolic process(GO:0042369) |
| 2.3 | 15.8 | GO:1902962 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 2.2 | 11.2 | GO:1902415 | regulation of mRNA binding(GO:1902415) regulation of RNA binding(GO:1905214) |
| 2.2 | 53.5 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
| 2.2 | 13.3 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 2.2 | 8.9 | GO:0002545 | chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880) |
| 2.2 | 15.4 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 2.2 | 19.7 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 2.2 | 28.4 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 2.2 | 28.1 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 2.1 | 8.5 | GO:0015791 | polyol transport(GO:0015791) |
| 2.1 | 10.5 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 2.1 | 14.7 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 2.1 | 33.3 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 2.1 | 8.3 | GO:0051984 | positive regulation of chromosome segregation(GO:0051984) |
| 2.1 | 92.5 | GO:0032392 | DNA geometric change(GO:0032392) |
| 2.1 | 194.8 | GO:0051225 | spindle assembly(GO:0051225) |
| 2.0 | 134.7 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 2.0 | 16.2 | GO:0097039 | protein linear polyubiquitination(GO:0097039) |
| 2.0 | 26.1 | GO:0071888 | macrophage apoptotic process(GO:0071888) |
| 2.0 | 14.0 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 2.0 | 143.8 | GO:0070126 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 2.0 | 6.0 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 2.0 | 58.7 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 1.9 | 23.2 | GO:0070986 | left/right axis specification(GO:0070986) |
| 1.9 | 7.7 | GO:0009956 | radial pattern formation(GO:0009956) |
| 1.9 | 3.8 | GO:0040031 | snRNA modification(GO:0040031) |
| 1.9 | 34.1 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 1.9 | 5.7 | GO:0002886 | regulation of myeloid leukocyte mediated immunity(GO:0002886) regulation of leukocyte degranulation(GO:0043300) |
| 1.9 | 9.5 | GO:1902739 | interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
| 1.9 | 3.8 | GO:0010040 | response to iron(II) ion(GO:0010040) |
| 1.8 | 3.7 | GO:1901224 | positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
| 1.8 | 12.8 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 1.8 | 21.9 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 1.8 | 7.2 | GO:1904457 | beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457) |
| 1.8 | 8.8 | GO:0070383 | DNA cytosine deamination(GO:0070383) |
| 1.8 | 24.6 | GO:0098779 | mitophagy in response to mitochondrial depolarization(GO:0098779) |
| 1.7 | 3.5 | GO:0070295 | renal water absorption(GO:0070295) |
| 1.7 | 56.7 | GO:0043687 | post-translational protein modification(GO:0043687) |
| 1.6 | 16.4 | GO:0010917 | negative regulation of mitochondrial membrane potential(GO:0010917) |
| 1.6 | 22.9 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 1.6 | 4.9 | GO:0042727 | flavin-containing compound biosynthetic process(GO:0042727) |
| 1.6 | 22.5 | GO:0006787 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 1.6 | 9.7 | GO:0046323 | regulation of glucose transport(GO:0010827) glucose import(GO:0046323) regulation of glucose import(GO:0046324) |
| 1.6 | 51.2 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 1.6 | 14.3 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 1.6 | 6.4 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 1.6 | 10.9 | GO:0035898 | parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828) |
| 1.6 | 4.7 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 1.6 | 3.1 | GO:0035608 | protein deglutamylation(GO:0035608) |
| 1.5 | 9.3 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 1.5 | 7.7 | GO:1905245 | regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 1.5 | 12.3 | GO:0015846 | polyamine transport(GO:0015846) |
| 1.5 | 9.0 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 1.5 | 4.5 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 1.5 | 4.4 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 1.5 | 5.9 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
| 1.5 | 65.5 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 1.5 | 66.7 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 1.4 | 2.9 | GO:0045013 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
| 1.4 | 60.7 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 1.4 | 10.0 | GO:0031929 | TOR signaling(GO:0031929) regulation of TOR signaling(GO:0032006) |
| 1.4 | 11.4 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 1.4 | 14.1 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 1.4 | 4.2 | GO:1900133 | renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) positive regulation of eosinophil degranulation(GO:0043311) regulation of renin secretion into blood stream(GO:1900133) positive regulation of eosinophil activation(GO:1902568) |
| 1.4 | 14.0 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 1.4 | 4.2 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 1.4 | 15.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 1.4 | 1.4 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 1.4 | 17.6 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 1.3 | 5.4 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 1.3 | 13.5 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 1.3 | 5.3 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 1.3 | 7.9 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 1.3 | 4.0 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 1.3 | 11.8 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 1.3 | 7.9 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 1.3 | 7.8 | GO:0030421 | defecation(GO:0030421) |
| 1.3 | 6.5 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
| 1.3 | 14.1 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 1.3 | 104.0 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 1.3 | 20.5 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
| 1.3 | 9.0 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 1.3 | 14.0 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 1.2 | 11.2 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 1.2 | 6.2 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 1.2 | 9.9 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
| 1.2 | 8.6 | GO:0008582 | regulation of synaptic growth at neuromuscular junction(GO:0008582) |
| 1.2 | 3.7 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
| 1.2 | 3.6 | GO:0060151 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 1.2 | 6.0 | GO:2000563 | positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) |
| 1.2 | 13.1 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 1.2 | 41.5 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 1.2 | 5.8 | GO:0060633 | negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) |
| 1.2 | 21.0 | GO:0002021 | response to dietary excess(GO:0002021) |
| 1.2 | 3.5 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
| 1.2 | 8.1 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 1.1 | 8.0 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 1.1 | 5.7 | GO:1903416 | response to glycoside(GO:1903416) |
| 1.1 | 41.0 | GO:0035329 | hippo signaling(GO:0035329) |
| 1.1 | 158.0 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 1.1 | 19.2 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 1.1 | 1.1 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 1.1 | 5.5 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 1.1 | 18.9 | GO:2000188 | regulation of cholesterol homeostasis(GO:2000188) |
| 1.1 | 13.2 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
| 1.1 | 28.6 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
| 1.1 | 4.4 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
| 1.1 | 4.3 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986) |
| 1.1 | 1.1 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) negative regulation of growth hormone secretion(GO:0060125) |
| 1.1 | 40.1 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 1.1 | 14.0 | GO:0045008 | depyrimidination(GO:0045008) |
| 1.1 | 50.4 | GO:0075733 | intracellular transport of virus(GO:0075733) |
| 1.1 | 43.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 1.1 | 16.0 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 1.1 | 98.0 | GO:0090114 | COPII-coated vesicle budding(GO:0090114) |
| 1.1 | 1.1 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 1.1 | 13.8 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 1.1 | 4.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 1.0 | 72.1 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 1.0 | 3.1 | GO:0014707 | branchiomeric skeletal muscle development(GO:0014707) |
| 1.0 | 5.2 | GO:2000035 | regulation of stem cell division(GO:2000035) |
| 1.0 | 6.1 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 1.0 | 24.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 1.0 | 8.1 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 1.0 | 7.9 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 1.0 | 4.9 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 1.0 | 3.9 | GO:0051958 | methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838) |
| 1.0 | 13.7 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 1.0 | 15.5 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
| 1.0 | 4.8 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
| 0.9 | 13.1 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) |
| 0.9 | 5.5 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.9 | 96.1 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.9 | 4.4 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.9 | 4.4 | GO:1902659 | regulation of glucose mediated signaling pathway(GO:1902659) |
| 0.9 | 8.7 | GO:0070525 | tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) |
| 0.9 | 6.9 | GO:0032310 | prostaglandin secretion(GO:0032310) |
| 0.9 | 4.3 | GO:0033489 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 0.9 | 35.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.9 | 12.8 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.9 | 1.7 | GO:0032489 | regulation of Cdc42 protein signal transduction(GO:0032489) |
| 0.9 | 7.7 | GO:0001825 | blastocyst formation(GO:0001825) |
| 0.8 | 49.9 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 0.8 | 12.5 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.8 | 3.3 | GO:0043335 | protein unfolding(GO:0043335) |
| 0.8 | 4.1 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.8 | 8.2 | GO:1904667 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667) |
| 0.8 | 12.3 | GO:1903540 | neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540) |
| 0.8 | 3.3 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.8 | 2.4 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.8 | 4.1 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
| 0.8 | 10.1 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.8 | 40.3 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.8 | 8.4 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.7 | 5.1 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.7 | 21.2 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
| 0.7 | 7.2 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.7 | 4.3 | GO:1990791 | amacrine cell differentiation(GO:0035881) dorsal root ganglion development(GO:1990791) |
| 0.7 | 2.7 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.7 | 6.0 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.7 | 17.2 | GO:0006513 | protein monoubiquitination(GO:0006513) |
| 0.7 | 18.4 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.7 | 35.5 | GO:0044364 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.6 | 16.7 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.6 | 18.3 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
| 0.6 | 13.1 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.6 | 3.7 | GO:1904550 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.6 | 5.6 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.6 | 4.3 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.6 | 56.1 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.6 | 7.0 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.6 | 10.6 | GO:0008228 | opsonization(GO:0008228) |
| 0.6 | 8.7 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.6 | 2.9 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.6 | 4.6 | GO:0018916 | nitrobenzene metabolic process(GO:0018916) |
| 0.6 | 9.2 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.6 | 7.9 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.6 | 2.2 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.6 | 30.3 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.5 | 2.7 | GO:0030047 | actin modification(GO:0030047) |
| 0.5 | 3.8 | GO:0015760 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.5 | 22.2 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.5 | 7.0 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.5 | 10.2 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
| 0.5 | 44.3 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.5 | 3.7 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.5 | 11.1 | GO:2000758 | positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758) |
| 0.5 | 1.1 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 0.5 | 4.7 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.5 | 2.1 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.5 | 4.1 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.5 | 6.1 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.5 | 3.0 | GO:2000146 | negative regulation of cell motility(GO:2000146) |
| 0.5 | 9.0 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.5 | 4.0 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.5 | 2.0 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.5 | 5.3 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.5 | 1.0 | GO:0010693 | negative regulation of alkaline phosphatase activity(GO:0010693) |
| 0.5 | 4.7 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.5 | 3.7 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.5 | 5.5 | GO:0039694 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.5 | 4.6 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.5 | 9.6 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.5 | 2.3 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 0.5 | 0.9 | GO:1904874 | positive regulation of telomerase RNA localization to Cajal body(GO:1904874) |
| 0.5 | 2.3 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.4 | 1.8 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.4 | 15.7 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.4 | 2.2 | GO:0032907 | transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) |
| 0.4 | 1.3 | GO:0060278 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 0.4 | 6.0 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.4 | 11.4 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.4 | 14.4 | GO:0001961 | positive regulation of cytokine-mediated signaling pathway(GO:0001961) |
| 0.4 | 12.7 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.4 | 2.5 | GO:0035803 | egg coat formation(GO:0035803) |
| 0.4 | 3.3 | GO:1900016 | negative regulation of cytokine production involved in inflammatory response(GO:1900016) |
| 0.4 | 10.3 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.4 | 10.8 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.4 | 10.7 | GO:0006401 | RNA catabolic process(GO:0006401) |
| 0.4 | 2.4 | GO:0030210 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.4 | 0.8 | GO:0046856 | phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.4 | 6.4 | GO:0002828 | regulation of type 2 immune response(GO:0002828) |
| 0.4 | 4.1 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.4 | 17.2 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.3 | 5.9 | GO:0007031 | peroxisome organization(GO:0007031) |
| 0.3 | 7.7 | GO:0072663 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.3 | 2.0 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.3 | 7.9 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.3 | 1.6 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.3 | 3.8 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.3 | 2.8 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.3 | 22.7 | GO:0006413 | translational initiation(GO:0006413) |
| 0.3 | 2.7 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.3 | 3.3 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.3 | 8.6 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.3 | 0.9 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.3 | 1.5 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.3 | 3.5 | GO:0006744 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.3 | 2.3 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.3 | 2.3 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.3 | 2.8 | GO:0042249 | establishment of planar polarity of embryonic epithelium(GO:0042249) |
| 0.3 | 15.5 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.3 | 20.2 | GO:0006695 | cholesterol biosynthetic process(GO:0006695) |
| 0.3 | 8.9 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.3 | 1.3 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.3 | 1.0 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.2 | 1.0 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.2 | 0.2 | GO:0044336 | canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) |
| 0.2 | 5.3 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.2 | 1.4 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.2 | 14.4 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.2 | 14.2 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.2 | 4.0 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.2 | 0.4 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.2 | 1.8 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.2 | 0.7 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.2 | 4.3 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.2 | 0.6 | GO:0034398 | telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.2 | 0.8 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
| 0.2 | 4.7 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
| 0.2 | 2.4 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.2 | 0.2 | GO:0072070 | loop of Henle development(GO:0072070) |
| 0.2 | 2.2 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
| 0.2 | 1.5 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.2 | 1.3 | GO:0023019 | signal transduction involved in regulation of gene expression(GO:0023019) |
| 0.2 | 0.8 | GO:0030238 | male sex determination(GO:0030238) |
| 0.2 | 6.0 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.2 | 1.9 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.2 | 1.5 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.2 | 1.7 | GO:0042407 | cristae formation(GO:0042407) |
| 0.1 | 10.2 | GO:0051963 | regulation of synapse assembly(GO:0051963) |
| 0.1 | 2.9 | GO:0019079 | viral genome replication(GO:0019079) |
| 0.1 | 1.5 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 1.6 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.1 | 0.2 | GO:0042117 | monocyte activation(GO:0042117) |
| 0.1 | 15.9 | GO:0006457 | protein folding(GO:0006457) |
| 0.1 | 8.0 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.1 | 1.3 | GO:0034380 | high-density lipoprotein particle assembly(GO:0034380) |
| 0.1 | 2.0 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.1 | 1.5 | GO:0032232 | negative regulation of actin filament bundle assembly(GO:0032232) |
| 0.1 | 1.5 | GO:0017038 | protein import into nucleus(GO:0006606) protein import(GO:0017038) protein targeting to nucleus(GO:0044744) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593) |
| 0.1 | 0.2 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.1 | 2.8 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.1 | 0.7 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.1 | 0.6 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 0.1 | 2.7 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 0.6 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.1 | 2.4 | GO:0031398 | positive regulation of protein ubiquitination(GO:0031398) |
| 0.1 | 1.3 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.1 | 1.2 | GO:0045727 | positive regulation of translation(GO:0045727) |
| 0.1 | 0.2 | GO:0006581 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 0.1 | 2.2 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.1 | 0.3 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.0 | 1.0 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.0 | GO:1901836 | regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) |
| 0.0 | 2.0 | GO:0018410 | C-terminal protein amino acid modification(GO:0018410) |
| 0.0 | 0.5 | GO:0035412 | regulation of catenin import into nucleus(GO:0035412) |
| 0.0 | 0.7 | GO:0042304 | regulation of fatty acid biosynthetic process(GO:0042304) |
| 0.0 | 2.6 | GO:0046718 | viral entry into host cell(GO:0046718) |
| 0.0 | 0.1 | GO:0030309 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.0 | 0.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 98.8 | 395.3 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 88.3 | 353.1 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 48.2 | 626.5 | GO:0042555 | MCM complex(GO:0042555) |
| 41.3 | 288.8 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 31.9 | 255.5 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 28.4 | 283.8 | GO:0000796 | condensin complex(GO:0000796) |
| 27.1 | 81.4 | GO:0018444 | translation release factor complex(GO:0018444) |
| 26.0 | 104.0 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 24.9 | 373.6 | GO:0045120 | pronucleus(GO:0045120) |
| 22.6 | 67.7 | GO:0033597 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 21.0 | 125.9 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 20.2 | 80.9 | GO:0031436 | BRCA1-BARD1 complex(GO:0031436) |
| 19.7 | 137.6 | GO:0016589 | NURF complex(GO:0016589) |
| 19.6 | 137.3 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 18.1 | 72.4 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 16.7 | 66.9 | GO:0000811 | GINS complex(GO:0000811) |
| 16.7 | 283.4 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 16.6 | 66.2 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 15.9 | 127.6 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 15.2 | 76.1 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 14.9 | 119.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 14.2 | 42.6 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 13.5 | 67.6 | GO:0017102 | methionyl glutamyl tRNA synthetase complex(GO:0017102) |
| 13.4 | 66.9 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 13.1 | 65.6 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 11.1 | 66.7 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 10.4 | 20.8 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 10.3 | 93.0 | GO:0005638 | lamin filament(GO:0005638) |
| 9.2 | 36.7 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 9.2 | 101.0 | GO:0005688 | U6 snRNP(GO:0005688) |
| 8.6 | 34.6 | GO:0042025 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 8.6 | 60.2 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 8.6 | 42.8 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 8.2 | 16.4 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 8.2 | 65.5 | GO:0001739 | sex chromatin(GO:0001739) |
| 7.9 | 39.4 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 7.8 | 54.4 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 7.6 | 22.9 | GO:0034676 | integrin alpha6-beta4 complex(GO:0034676) |
| 7.5 | 126.9 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 7.4 | 29.5 | GO:0001740 | Barr body(GO:0001740) |
| 7.0 | 70.1 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 7.0 | 21.0 | GO:0031523 | Myb complex(GO:0031523) |
| 6.9 | 27.4 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 6.7 | 53.6 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 6.5 | 78.5 | GO:0090543 | Flemming body(GO:0090543) |
| 6.5 | 64.9 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 6.5 | 77.7 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 6.4 | 64.2 | GO:0070187 | telosome(GO:0070187) |
| 6.3 | 82.3 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 6.2 | 43.5 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 5.8 | 29.2 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 5.7 | 39.9 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 5.5 | 49.7 | GO:0070652 | HAUS complex(GO:0070652) |
| 5.2 | 78.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 5.2 | 57.2 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 5.2 | 25.8 | GO:0071797 | LUBAC complex(GO:0071797) |
| 5.2 | 25.8 | GO:0032021 | NELF complex(GO:0032021) |
| 5.0 | 15.1 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 5.0 | 54.5 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 4.8 | 14.5 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 4.8 | 19.2 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 4.8 | 23.8 | GO:0000235 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 4.7 | 37.7 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 4.7 | 14.1 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 4.7 | 131.2 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 4.7 | 14.0 | GO:0034680 | integrin alpha1-beta1 complex(GO:0034665) integrin alpha3-beta1 complex(GO:0034667) integrin alpha8-beta1 complex(GO:0034678) integrin alpha10-beta1 complex(GO:0034680) |
| 4.7 | 14.0 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 4.6 | 41.8 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 4.6 | 9.1 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
| 4.5 | 40.7 | GO:0032059 | bleb(GO:0032059) |
| 4.5 | 49.8 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
| 4.5 | 27.1 | GO:0072589 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 4.5 | 44.7 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 4.4 | 35.1 | GO:0031931 | TORC1 complex(GO:0031931) |
| 4.4 | 8.7 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 4.3 | 29.9 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 4.2 | 38.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 4.2 | 58.9 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 4.2 | 66.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 4.1 | 28.6 | GO:0034709 | methylosome(GO:0034709) |
| 4.0 | 48.4 | GO:0030008 | TRAPP complex(GO:0030008) |
| 4.0 | 28.0 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 3.9 | 11.7 | GO:0036194 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 3.9 | 62.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 3.8 | 15.1 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 3.7 | 37.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 3.6 | 61.1 | GO:0005686 | U2 snRNP(GO:0005686) |
| 3.5 | 10.6 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 3.4 | 299.5 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 3.4 | 129.7 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 3.4 | 13.6 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 3.4 | 37.4 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 3.4 | 30.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 3.3 | 66.5 | GO:0030532 | small nuclear ribonucleoprotein complex(GO:0030532) |
| 3.3 | 13.3 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 3.3 | 118.5 | GO:0090544 | BAF-type complex(GO:0090544) |
| 3.3 | 9.9 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 3.3 | 26.1 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 3.2 | 22.6 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 3.1 | 40.1 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 3.0 | 82.2 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 3.0 | 121.3 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 3.0 | 27.0 | GO:0045261 | proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 3.0 | 8.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 2.9 | 14.7 | GO:0000938 | GARP complex(GO:0000938) |
| 2.9 | 17.4 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 2.7 | 24.3 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 2.7 | 64.1 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 2.7 | 50.4 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 2.6 | 15.8 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 2.5 | 7.6 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 2.3 | 44.6 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 2.2 | 46.9 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 2.2 | 22.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 2.2 | 136.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 2.2 | 37.2 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 2.2 | 4.4 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 2.0 | 14.3 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
| 2.0 | 11.9 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 2.0 | 181.2 | GO:0005643 | nuclear pore(GO:0005643) |
| 2.0 | 27.8 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 2.0 | 5.9 | GO:0000835 | ER ubiquitin ligase complex(GO:0000835) |
| 1.9 | 13.2 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 1.9 | 11.2 | GO:0031332 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 1.8 | 170.5 | GO:0070469 | respiratory chain(GO:0070469) |
| 1.8 | 5.3 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 1.8 | 12.4 | GO:0016272 | prefoldin complex(GO:0016272) |
| 1.8 | 10.5 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 1.7 | 13.3 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 1.6 | 138.1 | GO:0000502 | proteasome complex(GO:0000502) |
| 1.6 | 51.2 | GO:0030057 | desmosome(GO:0030057) |
| 1.6 | 47.9 | GO:0030686 | 90S preribosome(GO:0030686) |
| 1.6 | 14.2 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 1.6 | 11.0 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 1.6 | 40.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 1.6 | 70.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 1.5 | 74.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 1.5 | 4.6 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 1.5 | 36.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 1.5 | 7.4 | GO:0032449 | CBM complex(GO:0032449) |
| 1.4 | 72.4 | GO:0031430 | M band(GO:0031430) |
| 1.4 | 77.6 | GO:0005876 | spindle microtubule(GO:0005876) |
| 1.4 | 4.1 | GO:0044393 | microspike(GO:0044393) |
| 1.4 | 30.3 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 1.4 | 54.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 1.4 | 25.7 | GO:0046930 | pore complex(GO:0046930) |
| 1.3 | 24.2 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 1.3 | 5.4 | GO:0030891 | VCB complex(GO:0030891) |
| 1.3 | 9.3 | GO:0005652 | nuclear lamina(GO:0005652) |
| 1.3 | 160.8 | GO:0034399 | nuclear periphery(GO:0034399) |
| 1.3 | 13.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 1.3 | 35.4 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 1.3 | 6.5 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 1.3 | 33.8 | GO:1902562 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 1.3 | 3.9 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 1.3 | 8.9 | GO:0010369 | chromocenter(GO:0010369) |
| 1.3 | 67.3 | GO:0045171 | intercellular bridge(GO:0045171) |
| 1.2 | 5.0 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 1.2 | 14.8 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 1.2 | 57.6 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 1.2 | 7.2 | GO:0042587 | glycogen granule(GO:0042587) |
| 1.2 | 72.6 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 1.2 | 125.9 | GO:0016605 | PML body(GO:0016605) |
| 1.2 | 3.5 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059) |
| 1.2 | 120.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 1.1 | 4.6 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 1.1 | 25.1 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 1.1 | 4.3 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 1.1 | 20.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 1.1 | 10.8 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 1.1 | 13.9 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 1.0 | 39.3 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 1.0 | 66.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 1.0 | 22.6 | GO:0015935 | small ribosomal subunit(GO:0015935) |
| 1.0 | 11.6 | GO:0044754 | autolysosome(GO:0044754) |
| 0.9 | 10.3 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.9 | 2.8 | GO:0001652 | granular component(GO:0001652) |
| 0.9 | 4.5 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.9 | 0.9 | GO:0032302 | MutSbeta complex(GO:0032302) |
| 0.9 | 37.2 | GO:0016235 | aggresome(GO:0016235) |
| 0.8 | 125.2 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.8 | 58.9 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.8 | 12.4 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.8 | 251.5 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.8 | 8.2 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.8 | 200.5 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.8 | 1.6 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 0.8 | 10.5 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.8 | 59.6 | GO:0031970 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
| 0.8 | 52.1 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.8 | 81.4 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.8 | 35.9 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.7 | 7.4 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.7 | 9.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.7 | 4.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.7 | 4.2 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.7 | 11.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.7 | 12.7 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.7 | 2.0 | GO:0031417 | NatC complex(GO:0031417) |
| 0.6 | 74.8 | GO:0000785 | chromatin(GO:0000785) |
| 0.6 | 78.8 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.6 | 15.7 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.6 | 10.5 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.6 | 76.2 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.6 | 25.9 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.6 | 1.7 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.5 | 37.2 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.5 | 11.4 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 0.5 | 21.5 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.5 | 3.3 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
| 0.5 | 16.5 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.4 | 4.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.4 | 3.7 | GO:0000779 | condensed chromosome, centromeric region(GO:0000779) |
| 0.4 | 29.4 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.4 | 2.4 | GO:0032039 | integrator complex(GO:0032039) |
| 0.4 | 5.4 | GO:0030904 | retromer complex(GO:0030904) |
| 0.4 | 2.6 | GO:0030126 | COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663) |
| 0.3 | 10.4 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.3 | 37.6 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.3 | 1.3 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.3 | 12.0 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.3 | 89.5 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.3 | 92.7 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.3 | 3.8 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.3 | 9.2 | GO:0005840 | ribosome(GO:0005840) |
| 0.3 | 6.2 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.2 | 1.0 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.2 | 16.7 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.2 | 11.9 | GO:0005811 | lipid particle(GO:0005811) |
| 0.2 | 0.9 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.2 | 0.6 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.2 | 7.2 | GO:0005770 | late endosome(GO:0005770) |
| 0.2 | 44.8 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.2 | 8.2 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.2 | 19.9 | GO:0005874 | microtubule(GO:0005874) |
| 0.2 | 15.7 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.2 | 8.2 | GO:0030496 | midbody(GO:0030496) |
| 0.2 | 1.3 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.1 | 2.2 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 1.1 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 43.6 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 2.2 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 0.1 | 1.7 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 1.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 0.7 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 12.6 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.0 | 3.1 | GO:0005741 | mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968) |
| 0.0 | 0.3 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.2 | GO:0030027 | lamellipodium(GO:0030027) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 98.8 | 395.3 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 88.3 | 353.1 | GO:0032143 | single thymine insertion binding(GO:0032143) |
| 51.4 | 154.1 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 50.0 | 199.9 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 36.9 | 331.7 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 36.1 | 252.7 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 34.9 | 174.4 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 25.9 | 181.3 | GO:0050733 | RS domain binding(GO:0050733) |
| 22.2 | 311.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 20.3 | 61.0 | GO:0004139 | deoxyribose-phosphate aldolase activity(GO:0004139) |
| 19.3 | 57.9 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 18.2 | 109.5 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 18.2 | 72.7 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 17.3 | 104.0 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 17.1 | 51.3 | GO:1990404 | protein ADP-ribosylase activity(GO:1990404) |
| 17.1 | 51.2 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 16.3 | 81.4 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 15.1 | 45.2 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 14.2 | 56.9 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 14.0 | 41.9 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 12.8 | 115.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 12.8 | 76.7 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 12.4 | 37.1 | GO:0032139 | dinucleotide insertion or deletion binding(GO:0032139) |
| 12.0 | 36.0 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 11.9 | 47.4 | GO:0036033 | mediator complex binding(GO:0036033) |
| 11.8 | 35.3 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 11.2 | 503.7 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 11.1 | 66.7 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 10.9 | 141.6 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 10.7 | 32.1 | GO:0098625 | methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626) |
| 10.1 | 71.0 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 10.0 | 70.1 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 10.0 | 29.9 | GO:0045155 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155) |
| 9.6 | 9.6 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) |
| 9.4 | 273.9 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 9.2 | 46.1 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 9.1 | 72.9 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 8.8 | 35.4 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 8.3 | 66.2 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
| 8.2 | 49.0 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 7.8 | 86.0 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 7.8 | 23.4 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 7.8 | 163.9 | GO:0035173 | histone kinase activity(GO:0035173) |
| 7.8 | 318.6 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 7.6 | 60.4 | GO:0005497 | androgen binding(GO:0005497) |
| 7.4 | 111.6 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 7.4 | 22.1 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 6.5 | 19.6 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 6.5 | 58.6 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 6.5 | 26.0 | GO:0015207 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 6.3 | 25.4 | GO:0016886 | ligase activity, forming phosphoric ester bonds(GO:0016886) |
| 6.3 | 18.8 | GO:0004477 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 6.2 | 6.2 | GO:0051731 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 6.1 | 36.4 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 5.9 | 11.7 | GO:0043398 | HLH domain binding(GO:0043398) |
| 5.9 | 17.6 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 5.8 | 23.3 | GO:0016887 | ATPase activity(GO:0016887) |
| 5.7 | 17.0 | GO:0030984 | kininogen binding(GO:0030984) |
| 5.6 | 56.4 | GO:0042731 | PH domain binding(GO:0042731) |
| 5.5 | 16.6 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 5.3 | 147.8 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 5.3 | 168.6 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 5.0 | 114.9 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 4.9 | 19.7 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 4.9 | 9.8 | GO:0043142 | single-stranded DNA-dependent ATPase activity(GO:0043142) |
| 4.7 | 33.2 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) protein-disulfide reductase activity(GO:0047134) |
| 4.7 | 18.8 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 4.7 | 42.2 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 4.7 | 14.0 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 4.7 | 14.0 | GO:0050610 | oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
| 4.6 | 9.1 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 4.6 | 50.1 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 4.5 | 13.6 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 4.5 | 22.6 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 4.5 | 27.1 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 4.5 | 27.0 | GO:0043532 | angiostatin binding(GO:0043532) |
| 4.4 | 31.0 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 4.3 | 17.3 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 4.3 | 42.8 | GO:0043047 | single-stranded telomeric DNA binding(GO:0043047) |
| 4.2 | 185.8 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 4.2 | 42.0 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 4.1 | 16.4 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 4.1 | 8.2 | GO:0070990 | snRNP binding(GO:0070990) |
| 4.1 | 28.4 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 4.0 | 27.7 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 3.9 | 78.9 | GO:0005537 | mannose binding(GO:0005537) |
| 3.9 | 11.7 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
| 3.9 | 23.4 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 3.9 | 46.4 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 3.7 | 37.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 3.6 | 10.9 | GO:0097158 | pre-mRNA intronic pyrimidine-rich binding(GO:0097158) |
| 3.6 | 17.9 | GO:0046790 | virion binding(GO:0046790) |
| 3.6 | 7.2 | GO:0031177 | phosphopantetheine binding(GO:0031177) |
| 3.6 | 10.7 | GO:0017130 | poly(C) RNA binding(GO:0017130) |
| 3.6 | 100.1 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 3.6 | 88.9 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 3.6 | 10.7 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 3.5 | 10.5 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 3.4 | 13.5 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 3.4 | 43.7 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 3.3 | 9.9 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 3.2 | 63.5 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 3.2 | 28.4 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 3.1 | 62.3 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 3.0 | 63.9 | GO:0000339 | RNA cap binding(GO:0000339) |
| 3.0 | 57.8 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 3.0 | 54.4 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 3.0 | 11.9 | GO:0043515 | kinetochore binding(GO:0043515) |
| 3.0 | 137.4 | GO:0061650 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 3.0 | 11.8 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 2.9 | 14.4 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 2.9 | 11.5 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
| 2.9 | 145.5 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 2.8 | 8.5 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 2.8 | 14.0 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 2.8 | 11.2 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 2.8 | 14.0 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 2.8 | 19.6 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 2.8 | 11.1 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 2.8 | 13.8 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 2.7 | 21.9 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 2.7 | 143.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 2.6 | 13.2 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 2.6 | 47.3 | GO:0043274 | phospholipase binding(GO:0043274) |
| 2.6 | 15.6 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 2.6 | 153.9 | GO:0070888 | E-box binding(GO:0070888) |
| 2.6 | 43.6 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 2.5 | 50.2 | GO:0004532 | exoribonuclease activity(GO:0004532) |
| 2.5 | 234.3 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 2.5 | 77.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 2.5 | 17.2 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 2.4 | 39.0 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 2.4 | 21.8 | GO:0015288 | porin activity(GO:0015288) |
| 2.4 | 14.2 | GO:0030957 | Tat protein binding(GO:0030957) |
| 2.4 | 11.9 | GO:0052828 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 2.4 | 7.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 2.3 | 186.1 | GO:0004386 | helicase activity(GO:0004386) |
| 2.3 | 9.0 | GO:0004335 | galactokinase activity(GO:0004335) |
| 2.2 | 40.3 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 2.2 | 24.5 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 2.2 | 15.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 2.1 | 323.9 | GO:0042393 | histone binding(GO:0042393) |
| 2.1 | 56.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 2.1 | 6.2 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 2.1 | 22.7 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 2.1 | 16.5 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 2.0 | 8.2 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 2.0 | 6.1 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 2.0 | 30.1 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 1.9 | 7.8 | GO:0038025 | reelin receptor activity(GO:0038025) |
| 1.9 | 22.9 | GO:0038132 | neuregulin binding(GO:0038132) |
| 1.9 | 37.2 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 1.8 | 24.0 | GO:0031491 | nucleosome binding(GO:0031491) |
| 1.8 | 7.3 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 1.8 | 52.8 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 1.8 | 12.7 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 1.8 | 5.4 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 1.8 | 7.2 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 1.8 | 16.0 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 1.7 | 6.9 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 1.7 | 10.2 | GO:0000182 | rDNA binding(GO:0000182) |
| 1.6 | 3.3 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
| 1.6 | 16.1 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 1.6 | 19.1 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 1.6 | 6.4 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 1.6 | 7.9 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 1.6 | 18.9 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 1.6 | 4.7 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 1.6 | 84.2 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 1.6 | 17.1 | GO:0039706 | co-receptor binding(GO:0039706) |
| 1.5 | 13.7 | GO:0031386 | protein tag(GO:0031386) |
| 1.5 | 25.5 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 1.5 | 16.2 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
| 1.5 | 45.5 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 1.5 | 10.2 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 1.4 | 109.3 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 1.4 | 14.2 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 1.4 | 56.8 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 1.4 | 14.0 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 1.4 | 7.0 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
| 1.4 | 65.3 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 1.4 | 10.9 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 1.4 | 43.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 1.3 | 29.5 | GO:0008483 | transaminase activity(GO:0008483) |
| 1.3 | 15.8 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 1.3 | 14.4 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 1.3 | 140.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 1.3 | 268.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 1.3 | 7.8 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 1.3 | 6.5 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
| 1.3 | 20.6 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 1.3 | 3.8 | GO:0015526 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 1.3 | 3.8 | GO:0051538 | iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 1.2 | 5.0 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 1.2 | 32.3 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 1.2 | 9.5 | GO:0045545 | syndecan binding(GO:0045545) |
| 1.2 | 3.5 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 1.1 | 4.6 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 1.1 | 6.8 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 1.1 | 2.3 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 1.1 | 138.6 | GO:0032182 | ubiquitin-like protein binding(GO:0032182) |
| 1.1 | 18.1 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 1.1 | 83.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 1.1 | 7.7 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 1.1 | 6.5 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 1.1 | 7.4 | GO:0008201 | heparin binding(GO:0008201) |
| 1.1 | 10.6 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 1.1 | 3.2 | GO:0033867 | Fas-activated serine/threonine kinase activity(GO:0033867) |
| 1.0 | 8.0 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 1.0 | 13.8 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 1.0 | 3.9 | GO:0008518 | reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350) |
| 1.0 | 44.9 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
| 1.0 | 5.8 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.9 | 2.8 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.9 | 29.2 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.9 | 19.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.9 | 14.3 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.9 | 4.4 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.9 | 5.1 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.9 | 6.0 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.9 | 11.1 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.8 | 2.5 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.8 | 3.3 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.8 | 9.0 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.8 | 186.7 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.8 | 10.4 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.8 | 31.8 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.8 | 6.1 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.8 | 19.0 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.8 | 39.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.8 | 23.3 | GO:0004407 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
| 0.7 | 16.9 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.7 | 7.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.7 | 130.5 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
| 0.7 | 6.5 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.7 | 7.2 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.7 | 30.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.7 | 9.9 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.7 | 4.2 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.7 | 3.5 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.7 | 25.0 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.7 | 13.1 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.7 | 36.5 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
| 0.7 | 9.6 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.7 | 4.1 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.7 | 4.0 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.6 | 24.3 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.6 | 1.9 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.6 | 1.8 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.6 | 15.9 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.6 | 5.9 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.6 | 38.8 | GO:0051287 | NAD binding(GO:0051287) |
| 0.6 | 1.7 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 0.6 | 6.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.5 | 4.3 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.5 | 4.8 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.5 | 10.1 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.5 | 80.5 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.5 | 41.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.5 | 141.0 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.5 | 13.9 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.5 | 3.2 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.5 | 22.9 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.5 | 2.3 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.5 | 14.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.4 | 36.8 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.4 | 6.4 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.4 | 6.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.4 | 362.5 | GO:0003723 | RNA binding(GO:0003723) |
| 0.4 | 28.8 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.4 | 4.4 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.4 | 11.4 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.4 | 1.9 | GO:0030151 | molybdenum ion binding(GO:0030151) |
| 0.4 | 8.1 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.4 | 3.4 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.3 | 3.5 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.3 | 10.6 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.3 | 10.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.3 | 2.5 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.3 | 4.3 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.3 | 9.9 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.3 | 2.0 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.3 | 7.6 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.3 | 2.8 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859) |
| 0.3 | 2.5 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.3 | 4.2 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.3 | 3.9 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
| 0.3 | 1.3 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
| 0.2 | 4.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.2 | 7.7 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.2 | 3.1 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.2 | 9.0 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.2 | 9.1 | GO:0043621 | protein self-association(GO:0043621) |
| 0.2 | 2.4 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.2 | 0.8 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.2 | 5.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.2 | 1.5 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.1 | 3.0 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.1 | 41.8 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.1 | 39.1 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 0.7 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.1 | 9.2 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.1 | 36.6 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.1 | 7.5 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.1 | 1.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.8 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.1 | 1.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 2.7 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 7.8 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
| 0.1 | 0.8 | GO:0097493 | extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493) |
| 0.1 | 2.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 1.0 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 3.8 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 7.4 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.1 | 0.3 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.1 | 1.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 1.1 | GO:0044877 | macromolecular complex binding(GO:0044877) |
| 0.1 | 0.9 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.1 | 3.5 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 5.7 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.1 | 0.5 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 4.2 | GO:0016301 | kinase activity(GO:0016301) |
| 0.0 | 0.9 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
| 0.0 | 0.8 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.0 | 1.4 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.2 | 1303.2 | PID E2F PATHWAY | E2F transcription factor network |
| 12.1 | 302.4 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 8.9 | 544.3 | PID ATR PATHWAY | ATR signaling pathway |
| 6.1 | 98.2 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 3.9 | 239.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 3.9 | 34.7 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 3.4 | 115.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 2.7 | 258.2 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 2.6 | 96.5 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 2.4 | 251.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 2.3 | 51.8 | PID ATM PATHWAY | ATM pathway |
| 2.0 | 87.8 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 2.0 | 51.7 | PID BARD1 PATHWAY | BARD1 signaling events |
| 1.7 | 102.9 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 1.7 | 290.8 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 1.7 | 46.5 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 1.6 | 31.0 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 1.6 | 91.4 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 1.6 | 28.0 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 1.6 | 103.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 1.5 | 63.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 1.5 | 37.1 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 1.5 | 16.0 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 1.4 | 133.8 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 1.4 | 4.2 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 1.3 | 52.0 | PID PLK1 PATHWAY | PLK1 signaling events |
| 1.3 | 22.9 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 1.2 | 23.4 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 1.2 | 37.9 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 1.2 | 7.2 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 1.1 | 9.8 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.9 | 49.4 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.8 | 8.0 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.8 | 20.7 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.8 | 26.6 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.8 | 32.2 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.7 | 7.9 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.6 | 4.5 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.6 | 8.6 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.6 | 8.8 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.5 | 16.9 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.5 | 22.8 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.5 | 27.9 | PID P73PATHWAY | p73 transcription factor network |
| 0.5 | 28.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.5 | 34.8 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.5 | 2.9 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.5 | 8.9 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.5 | 14.9 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.4 | 2.5 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.4 | 24.8 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.4 | 11.9 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.3 | 4.5 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.3 | 17.3 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.3 | 5.7 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.3 | 7.7 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.3 | 3.1 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.2 | 1.6 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.1 | 3.3 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 3.0 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.1 | 3.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 7.2 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 3.5 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.1 | 4.8 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 2.9 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.1 | 2.3 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 45.2 | 723.6 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 23.8 | 356.7 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 21.5 | 516.9 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 18.8 | 150.1 | REACTOME DNA STRAND ELONGATION | Genes involved in DNA strand elongation |
| 15.2 | 242.5 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 11.2 | 359.8 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 10.5 | 209.3 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 10.0 | 190.2 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 9.7 | 357.7 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 8.6 | 146.5 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 8.5 | 144.1 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 7.8 | 241.3 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 7.7 | 130.2 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 7.1 | 85.7 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 6.5 | 26.0 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 6.3 | 196.4 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 6.0 | 36.2 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 6.0 | 144.5 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 5.4 | 315.5 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 4.8 | 566.4 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 4.7 | 65.2 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 4.3 | 68.9 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 4.2 | 75.8 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 4.2 | 50.0 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 3.6 | 129.8 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 3.6 | 135.3 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 3.5 | 60.3 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 3.5 | 79.9 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 3.4 | 60.7 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 3.1 | 87.8 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 3.1 | 25.0 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 3.0 | 83.5 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 2.9 | 61.5 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 2.9 | 117.6 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 2.8 | 42.6 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 2.7 | 127.4 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 2.6 | 13.1 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 2.5 | 35.4 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 2.4 | 65.5 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 2.4 | 47.8 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 2.3 | 88.1 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 2.2 | 51.2 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 2.2 | 98.1 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 2.2 | 165.4 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 2.1 | 10.7 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
| 2.1 | 72.8 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 2.1 | 174.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 2.0 | 154.6 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 2.0 | 336.5 | REACTOME TRANSLATION | Genes involved in Translation |
| 2.0 | 35.3 | REACTOME TRNA AMINOACYLATION | Genes involved in tRNA Aminoacylation |
| 2.0 | 42.9 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 1.9 | 7.8 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 1.9 | 42.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 1.9 | 40.3 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 1.8 | 20.3 | REACTOME GLOBAL GENOMIC NER GG NER | Genes involved in Global Genomic NER (GG-NER) |
| 1.8 | 56.5 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 1.8 | 12.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 1.7 | 15.7 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 1.7 | 34.7 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 1.7 | 51.7 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 1.7 | 148.6 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 1.6 | 244.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 1.6 | 31.9 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 1.6 | 23.9 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 1.5 | 39.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 1.5 | 72.4 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 1.5 | 38.5 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 1.4 | 12.4 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 1.3 | 10.0 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 1.2 | 18.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 1.2 | 23.4 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 1.2 | 19.2 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 1.1 | 53.2 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 1.1 | 9.8 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 1.1 | 35.7 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 1.0 | 35.0 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 1.0 | 21.9 | REACTOME METABOLISM OF NUCLEOTIDES | Genes involved in Metabolism of nucleotides |
| 0.9 | 43.7 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.8 | 35.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.7 | 4.5 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.7 | 3.7 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
| 0.7 | 41.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.7 | 12.6 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.7 | 17.2 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.7 | 18.5 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.7 | 8.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.6 | 14.4 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.6 | 6.2 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.5 | 4.3 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.5 | 7.2 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.5 | 8.6 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.5 | 11.7 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.5 | 7.9 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.4 | 7.7 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.4 | 2.3 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.4 | 17.3 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.4 | 6.6 | REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
| 0.4 | 11.7 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.3 | 11.4 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.3 | 7.7 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.3 | 37.4 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.3 | 17.9 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.3 | 3.8 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.3 | 6.5 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.3 | 5.6 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.3 | 3.5 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.3 | 6.1 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.3 | 5.6 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.2 | 3.0 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.2 | 6.7 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.2 | 3.7 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.2 | 2.8 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.2 | 7.0 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 4.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 1.5 | REACTOME OPSINS | Genes involved in Opsins |
| 0.1 | 1.3 | REACTOME PEPTIDE HORMONE BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
| 0.1 | 3.0 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.1 | 0.9 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.1 | 1.7 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.2 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |