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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EBF3

Z-value: 1.17

Motif logo

Transcription factors associated with EBF3

Gene Symbol Gene ID Gene Info
ENSG00000108001.9 EBF transcription factor 3

Activity profile of EBF3 motif

Sorted Z-values of EBF3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153517473 13.64 ENST00000368715.1
S100 calcium binding protein A4
chr1_-_113247543 12.36 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr7_-_100881041 11.28 ENST00000412417.1
ENST00000414035.1
claudin 15
chr8_+_22436248 11.08 ENST00000308354.7
PDZ and LIM domain 2 (mystique)
chr7_+_75932863 10.96 ENST00000429938.1
heat shock 27kDa protein 1
chr22_-_37640277 10.56 ENST00000401529.3
ENST00000249071.6
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_-_154943212 10.09 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC (Src homology 2 domain containing) transforming protein 1
chr7_-_6523688 9.67 ENST00000490996.1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr1_-_154943002 9.53 ENST00000606391.1
SHC (Src homology 2 domain containing) transforming protein 1
chr11_-_67120974 9.44 ENST00000539074.1
ENST00000312419.3
polymerase (DNA-directed), delta 4, accessory subunit
chr6_-_7911042 9.44 ENST00000379757.4
thioredoxin domain containing 5 (endoplasmic reticulum)
chr16_+_3068393 9.03 ENST00000573001.1
tumor necrosis factor receptor superfamily, member 12A
chr19_-_40331345 8.66 ENST00000597224.1
fibrillarin
chr11_+_75273101 8.23 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr19_+_50180317 7.90 ENST00000534465.1
protein arginine methyltransferase 1
chr11_+_75273246 7.77 ENST00000526397.1
ENST00000529643.1
ENST00000525492.1
ENST00000530284.1
ENST00000532356.1
ENST00000524558.1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr1_+_32757668 7.67 ENST00000373548.3
histone deacetylase 1
chr8_+_22436635 7.53 ENST00000452226.1
ENST00000397760.4
ENST00000339162.7
ENST00000397761.2
PDZ and LIM domain 2 (mystique)
chr7_-_137686791 7.41 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
cAMP responsive element binding protein 3-like 2
chr3_-_142608001 7.24 ENST00000295992.3
procollagen C-endopeptidase enhancer 2
chr11_+_114128522 7.21 ENST00000535401.1
nicotinamide N-methyltransferase
chr5_+_154393260 6.56 ENST00000435029.4
kinesin family member 4B
chrX_+_69509927 6.45 ENST00000374403.3
kinesin family member 4A
chr19_+_50180409 6.15 ENST00000391851.4
protein arginine methyltransferase 1
chr19_+_13049413 6.14 ENST00000316448.5
ENST00000588454.1
calreticulin
chr3_+_184018352 6.14 ENST00000435761.1
ENST00000439383.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr22_+_24309089 5.94 ENST00000215770.5
D-dopachrome tautomerase-like
chr19_+_42381337 5.94 ENST00000597454.1
ENST00000444740.2
CD79a molecule, immunoglobulin-associated alpha
chr19_+_50180507 5.90 ENST00000454376.2
ENST00000524771.1
protein arginine methyltransferase 1
chr19_+_49403562 5.89 ENST00000407032.1
ENST00000452087.1
ENST00000411700.1
nucleobindin 1
chr12_-_54694807 5.88 ENST00000435572.2
nuclear factor, erythroid 2
chr12_-_106641728 5.84 ENST00000378026.4
cytoskeleton-associated protein 4
chr2_-_219151487 5.64 ENST00000444881.1
transmembrane BAX inhibitor motif containing 1
chr22_-_37640456 5.58 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr3_-_145878954 5.40 ENST00000282903.5
ENST00000360060.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr5_-_180669197 5.37 ENST00000502905.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr22_-_19466732 5.35 ENST00000263202.10
ENST00000360834.4
ubiquitin fusion degradation 1 like (yeast)
chr22_-_19466683 5.31 ENST00000399523.1
ENST00000421968.2
ENST00000447868.1
ubiquitin fusion degradation 1 like (yeast)
chr14_+_101193164 5.28 ENST00000341267.4
delta-like 1 homolog (Drosophila)
chr17_-_40075197 5.24 ENST00000590770.1
ENST00000590151.1
ATP citrate lyase
chr12_-_54694758 5.11 ENST00000553070.1
nuclear factor, erythroid 2
chr3_+_38179969 5.07 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
myeloid differentiation primary response 88
chr11_-_46142948 5.07 ENST00000257821.4
PHD finger protein 21A
chr3_-_149293990 5.05 ENST00000472417.1
WW domain containing transcription regulator 1
chr15_+_74218787 5.05 ENST00000261921.7
lysyl oxidase-like 1
chr19_-_45826125 5.04 ENST00000221476.3
creatine kinase, muscle
chr14_+_101193246 5.01 ENST00000331224.6
delta-like 1 homolog (Drosophila)
chr17_+_39975455 4.96 ENST00000455106.1
FK506 binding protein 10, 65 kDa
chr17_-_40075219 4.91 ENST00000537919.1
ENST00000352035.2
ENST00000353196.1
ENST00000393896.2
ATP citrate lyase
chr7_+_100464760 4.89 ENST00000200457.4
thyroid hormone receptor interactor 6
chr11_+_20385327 4.87 ENST00000451739.2
ENST00000532505.1
HIV-1 Tat interactive protein 2, 30kDa
chr5_-_180669236 4.85 ENST00000507756.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr19_+_33865218 4.84 ENST00000585933.2
CCAAT/enhancer binding protein (C/EBP), gamma
chr11_-_67169253 4.79 ENST00000527663.1
ENST00000312989.7
protein phosphatase 1, catalytic subunit, alpha isozyme
chr14_-_106725723 4.76 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr7_+_77167376 4.76 ENST00000435495.2
protein tyrosine phosphatase, non-receptor type 12
chr1_+_26869597 4.76 ENST00000530003.1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr8_+_145582217 4.64 ENST00000530047.1
ENST00000527078.1
solute carrier family 52 (riboflavin transporter), member 2
chr22_-_24316648 4.61 ENST00000403754.3
ENST00000430101.2
ENST00000398344.4
D-dopachrome tautomerase
chr3_-_67705006 4.61 ENST00000492795.1
ENST00000493112.1
ENST00000307227.5
succinate-CoA ligase, GDP-forming, beta subunit
chr19_-_39108552 4.56 ENST00000591517.1
mitogen-activated protein kinase kinase kinase kinase 1
chr16_+_69958887 4.55 ENST00000568684.1
WW domain containing E3 ubiquitin protein ligase 2
chr14_-_106586656 4.54 ENST00000390602.2
immunoglobulin heavy variable 3-13
chr19_-_39108643 4.50 ENST00000396857.2
mitogen-activated protein kinase kinase kinase kinase 1
chrX_-_152989798 4.48 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
B-cell receptor-associated protein 31
chr3_-_142607740 4.47 ENST00000485766.1
procollagen C-endopeptidase enhancer 2
chr7_-_6523755 4.45 ENST00000436575.1
ENST00000258739.4
diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr7_-_132766818 4.38 ENST00000262570.5
coiled-coil-helix-coiled-coil-helix domain containing 3
chr6_-_45983581 4.38 ENST00000339561.6
chloride intracellular channel 5
chr3_-_189840223 4.37 ENST00000427335.2
leprecan-like 1
chr1_-_206785789 4.34 ENST00000437518.1
ENST00000367114.3
eukaryotic translation initiation factor 2D
chr14_-_24664776 4.34 ENST00000530468.1
ENST00000528010.1
ENST00000396854.4
ENST00000524835.1
ENST00000261789.4
ENST00000525592.1
transmembrane 9 superfamily member 1
chr17_+_39975544 4.33 ENST00000544340.1
FK506 binding protein 10, 65 kDa
chr7_-_99698338 4.24 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr8_+_145582231 4.24 ENST00000526338.1
ENST00000402965.1
ENST00000534725.1
ENST00000532887.1
ENST00000329994.2
solute carrier family 52 (riboflavin transporter), member 2
chr10_-_102089729 4.23 ENST00000465680.2
polycystic kidney disease 2-like 1
chr3_-_52273098 4.23 ENST00000499914.2
ENST00000305533.5
ENST00000597542.1
twinfilin actin-binding protein 2
toll-like receptor 9
chr2_-_188378368 4.21 ENST00000392365.1
ENST00000435414.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr7_-_44180673 4.18 ENST00000457314.1
ENST00000447951.1
ENST00000431007.1
myosin, light chain 7, regulatory
chr8_+_145582633 4.17 ENST00000540505.1
solute carrier family 52 (riboflavin transporter), member 2
chr16_+_33605231 4.16 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr11_+_60223225 4.16 ENST00000524807.1
ENST00000345732.4
membrane-spanning 4-domains, subfamily A, member 1
chr15_-_20193370 4.16 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr11_+_60223312 4.15 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
membrane-spanning 4-domains, subfamily A, member 1
chr7_-_132766800 4.15 ENST00000542753.1
ENST00000448878.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr11_-_64545941 4.12 ENST00000377387.1
splicing factor 1
chrX_+_155110956 4.05 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
vesicle-associated membrane protein 7
chr14_+_105952648 3.99 ENST00000330233.7
cysteine-rich protein 1 (intestinal)
chr7_-_44180884 3.94 ENST00000458240.1
ENST00000223364.3
myosin, light chain 7, regulatory
chr14_-_24664540 3.91 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
transmembrane 9 superfamily member 1
chrX_+_48644962 3.87 ENST00000376670.3
ENST00000376665.3
GATA binding protein 1 (globin transcription factor 1)
chr14_-_107131560 3.86 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr11_+_20385231 3.83 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HIV-1 Tat interactive protein 2, 30kDa
chr6_+_43737939 3.77 ENST00000372067.3
vascular endothelial growth factor A
chr6_-_10419871 3.74 ENST00000319516.4
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr7_+_77167343 3.73 ENST00000433369.2
ENST00000415482.2
protein tyrosine phosphatase, non-receptor type 12
chr9_-_139581848 3.72 ENST00000538402.1
ENST00000371694.3
1-acylglycerol-3-phosphate O-acyltransferase 2
chr19_-_39108568 3.70 ENST00000586296.1
mitogen-activated protein kinase kinase kinase kinase 1
chr20_-_48732472 3.65 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
ubiquitin-conjugating enzyme E2 variant 1
chr1_+_11072696 3.64 ENST00000240185.3
ENST00000476201.1
TAR DNA binding protein
chr7_-_100240328 3.63 ENST00000462107.1
transferrin receptor 2
chr11_-_65381643 3.55 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr11_+_1860200 3.55 ENST00000381911.1
troponin I type 2 (skeletal, fast)
chr10_+_73724123 3.53 ENST00000373115.4
carbohydrate (chondroitin 6) sulfotransferase 3
chr14_+_105953246 3.49 ENST00000392531.3
cysteine-rich protein 1 (intestinal)
chr11_+_1942580 3.48 ENST00000381558.1
troponin T type 3 (skeletal, fast)
chr11_-_64546202 3.47 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
splicing factor 1
chr9_+_135854091 3.46 ENST00000450530.1
ENST00000534944.1
growth factor independent 1B transcription repressor
chr6_+_31555045 3.45 ENST00000396101.3
ENST00000490742.1
leukocyte specific transcript 1
chr3_-_49170522 3.44 ENST00000418109.1
laminin, beta 2 (laminin S)
chr16_+_67233007 3.41 ENST00000360833.1
ENST00000393997.2
engulfment and cell motility 3
chr11_+_128562372 3.37 ENST00000344954.6
Fli-1 proto-oncogene, ETS transcription factor
chr16_-_33647696 3.36 ENST00000558425.1
ENST00000569103.2
Uncharacterized protein
chr1_+_153330322 3.36 ENST00000368738.3
S100 calcium binding protein A9
chr11_-_33744487 3.34 ENST00000426650.2
CD59 molecule, complement regulatory protein
chr2_-_219134822 3.32 ENST00000444053.1
ENST00000248450.4
angio-associated, migratory cell protein
chr19_+_46010674 3.28 ENST00000245932.6
ENST00000592139.1
ENST00000590603.1
vasodilator-stimulated phosphoprotein
chr1_-_222885770 3.26 ENST00000355727.2
ENST00000340020.6
axin interactor, dorsalization associated
chr5_-_133340326 3.26 ENST00000425992.1
ENST00000395044.3
ENST00000395047.2
voltage-dependent anion channel 1
chr4_+_37892682 3.25 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr7_-_100881109 3.23 ENST00000308344.5
claudin 15
chr11_+_2466218 3.22 ENST00000155840.5
potassium voltage-gated channel, KQT-like subfamily, member 1
chr17_-_80023401 3.20 ENST00000354321.7
ENST00000306796.5
dihydrouridine synthase 1-like (S. cerevisiae)
chr3_-_16524357 3.19 ENST00000432519.1
raftlin, lipid raft linker 1
chr19_+_41107249 3.19 ENST00000396819.3
latent transforming growth factor beta binding protein 4
chr14_+_105953204 3.18 ENST00000409393.2
cysteine-rich protein 1 (intestinal)
chr14_-_106994333 3.17 ENST00000390624.2
immunoglobulin heavy variable 3-48
chr9_-_111775772 3.15 ENST00000325580.6
ENST00000374593.4
ENST00000374595.4
ENST00000325551.4
catenin (cadherin-associated protein), alpha-like 1
chr11_+_1860682 3.14 ENST00000381906.1
troponin I type 2 (skeletal, fast)
chr19_+_42381173 3.12 ENST00000221972.3
CD79a molecule, immunoglobulin-associated alpha
chr18_-_23670546 3.11 ENST00000542743.1
ENST00000545952.1
ENST00000539849.1
ENST00000415083.2
synovial sarcoma translocation, chromosome 18
chrX_-_74376108 3.10 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr3_-_49170405 3.08 ENST00000305544.4
ENST00000494831.1
laminin, beta 2 (laminin S)
chrX_-_48827976 3.07 ENST00000218176.3
potassium voltage-gated channel, Shal-related subfamily, member 1
chr8_+_22446763 3.03 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
Uncharacterized protein
chr9_-_139581875 3.01 ENST00000371696.2
1-acylglycerol-3-phosphate O-acyltransferase 2
chr22_-_43411106 3.00 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
protein kinase C and casein kinase substrate in neurons 2
chr14_-_106816253 2.96 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr4_-_140223614 2.95 ENST00000394223.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr11_-_6640585 2.93 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
tripeptidyl peptidase I
chr12_-_51663728 2.91 ENST00000603864.1
ENST00000605426.1
small cell adhesion glycoprotein
chr1_+_161719552 2.90 ENST00000367943.4
dual specificity phosphatase 12
chr2_+_27301435 2.89 ENST00000380320.4
elastin microfibril interfacer 1
chr2_-_174830430 2.86 ENST00000310015.6
ENST00000455789.2
Sp3 transcription factor
chr2_+_46769798 2.85 ENST00000238738.4
ras homolog family member Q
chr14_-_106552755 2.84 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr2_+_119981384 2.81 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
STEAP family member 3, metalloreductase
chr18_-_48723690 2.78 ENST00000406189.3
mex-3 RNA binding family member C
chr17_-_62009702 2.76 ENST00000006750.3
CD79b molecule, immunoglobulin-associated beta
chr14_-_106518922 2.76 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr5_-_146833222 2.75 ENST00000534907.1
dihydropyrimidinase-like 3
chr1_+_2487800 2.65 ENST00000355716.4
tumor necrosis factor receptor superfamily, member 14
chr11_+_1860832 2.64 ENST00000252898.7
troponin I type 2 (skeletal, fast)
chr14_-_106791536 2.63 ENST00000390613.2
immunoglobulin heavy variable 3-30
chr17_-_62009621 2.62 ENST00000349817.2
ENST00000392795.3
CD79b molecule, immunoglobulin-associated beta
chr11_-_72432950 2.61 ENST00000426523.1
ENST00000429686.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr16_-_28506840 2.59 ENST00000569430.1
ceroid-lipofuscinosis, neuronal 3
chr5_-_142783694 2.58 ENST00000394466.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr5_-_180668605 2.56 ENST00000504128.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr1_+_153747746 2.53 ENST00000368661.3
solute carrier family 27 (fatty acid transporter), member 3
chr16_+_67233412 2.53 ENST00000477898.1
engulfment and cell motility 3
chrX_-_10645773 2.52 ENST00000453318.2
midline 1 (Opitz/BBB syndrome)
chr16_-_89007491 2.48 ENST00000327483.5
ENST00000564416.1
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr19_+_984313 2.47 ENST00000251289.5
ENST00000587001.2
ENST00000607440.1
WD repeat domain 18
chr19_-_6591113 2.44 ENST00000423145.3
ENST00000245903.3
CD70 molecule
chr20_+_62496596 2.44 ENST00000369927.4
ENST00000346249.4
ENST00000348257.5
ENST00000352482.4
ENST00000351424.4
ENST00000217121.5
ENST00000358548.4
tumor protein D52-like 2
chr14_-_23540826 2.40 ENST00000357481.2
apoptotic chromatin condensation inducer 1
chr3_-_88108192 2.32 ENST00000309534.6
CGG triplet repeat binding protein 1
chr17_+_73663402 2.31 ENST00000355423.3
SAP30 binding protein
chr17_-_79881408 2.30 ENST00000392366.3
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr10_+_99332198 2.27 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ankyrin repeat domain 2 (stretch responsive muscle)
chr7_-_105752651 2.24 ENST00000470347.1
ENST00000455385.2
synaptophysin-like 1
chr10_+_114709999 2.23 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_-_27632390 2.21 ENST00000350803.4
ENST00000344034.4
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr7_-_6098770 2.18 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
eukaryotic translation initiation factor 2-alpha kinase 1
chr6_+_43738444 2.16 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
vascular endothelial growth factor A
chr5_+_34915444 2.14 ENST00000336767.5
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr17_+_75315534 2.14 ENST00000590294.1
ENST00000329047.8
septin 9
chr5_-_138725594 2.14 ENST00000302125.8
marginal zone B and B1 cell-specific protein
chr6_+_7107999 2.13 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
ras responsive element binding protein 1
chr13_+_29233218 2.12 ENST00000380842.4
proteasome maturation protein
chr7_+_48128194 2.11 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
uridine phosphorylase 1
chr14_+_24590560 2.10 ENST00000558325.1
RP11-468E2.6
chr12_-_7261772 2.10 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
complement component 1, r subcomponent-like
chr5_-_138725560 2.09 ENST00000412103.2
ENST00000457570.2
marginal zone B and B1 cell-specific protein
chr9_+_134103496 2.08 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
nucleoporin 214kDa
chr14_-_65569244 2.08 ENST00000557277.1
ENST00000556892.1
MYC associated factor X
chr1_-_156828810 2.07 ENST00000368195.3
insulin receptor-related receptor
chr10_-_102090243 2.06 ENST00000338519.3
ENST00000353274.3
ENST00000318222.3
polycystic kidney disease 2-like 1
chr2_+_89986318 2.05 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr1_+_32084794 2.05 ENST00000373705.1
hypocretin (orexin) receptor 1
chr7_+_48128316 2.05 ENST00000341253.4
uridine phosphorylase 1
chrX_-_153637612 2.04 ENST00000369807.1
ENST00000369808.3
deoxyribonuclease I-like 1
chr1_+_110198944 2.03 ENST00000369833.1
glutathione S-transferase mu 4
chr9_-_130635741 2.03 ENST00000223836.10
adenylate kinase 1
chr2_-_90538397 2.00 ENST00000443397.3
Uncharacterized protein
chr16_+_33020496 2.00 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chrX_+_105937068 2.00 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chr1_-_1310530 1.97 ENST00000338370.3
ENST00000321751.5
ENST00000378853.3
aurora kinase A interacting protein 1
chr10_+_99332529 1.96 ENST00000455090.1
ankyrin repeat domain 2 (stretch responsive muscle)

Network of associatons between targets according to the STRING database.

First level regulatory network of EBF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 20.0 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
3.3 13.1 GO:0032218 riboflavin transport(GO:0032218)
3.1 9.3 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
2.7 11.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
2.2 2.2 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
2.2 8.7 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
2.1 10.7 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
2.1 12.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
2.0 22.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
2.0 15.7 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.8 5.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.6 4.8 GO:0060319 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) primitive erythrocyte differentiation(GO:0060319)
1.5 7.7 GO:0061198 fungiform papilla formation(GO:0061198)
1.5 7.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
1.4 5.6 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
1.4 2.8 GO:0003415 chondrocyte hypertrophy(GO:0003415)
1.4 4.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
1.3 6.5 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
1.3 14.1 GO:0006621 protein retention in ER lumen(GO:0006621)
1.2 3.6 GO:2000909 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
1.2 4.8 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
1.1 9.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.1 3.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.1 4.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
1.1 4.2 GO:1901895 positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
1.0 5.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
1.0 4.2 GO:0006218 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
1.0 6.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
1.0 5.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
1.0 14.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.9 3.7 GO:0003409 optic cup structural organization(GO:0003409)
0.9 4.6 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.9 4.5 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.8 4.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.8 3.3 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.8 3.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.8 3.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.7 3.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.7 8.5 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.7 4.9 GO:0050915 sensory perception of sour taste(GO:0050915)
0.7 4.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.7 5.9 GO:0072718 response to cisplatin(GO:0072718)
0.6 2.6 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.6 10.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.6 5.0 GO:0006600 creatine metabolic process(GO:0006600)
0.6 2.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.6 3.6 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.6 1.8 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.6 7.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.6 1.2 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.6 13.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.6 2.8 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.5 15.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.5 4.3 GO:0032790 ribosome disassembly(GO:0032790)
0.5 3.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.5 3.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.5 4.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.5 19.6 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.5 4.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.5 2.9 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.5 1.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.5 2.9 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.5 4.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.5 5.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.5 5.5 GO:0090168 Golgi reassembly(GO:0090168)
0.4 6.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.4 1.8 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.4 1.3 GO:1990637 response to prolactin(GO:1990637)
0.4 1.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.4 1.7 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.4 0.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.4 1.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.4 3.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.4 0.8 GO:1903423 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.4 3.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.4 3.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.4 9.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.4 2.6 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.4 5.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.4 3.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.4 2.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 2.4 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 1.4 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.3 3.0 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.3 1.0 GO:0002818 intracellular defense response(GO:0002818)
0.3 1.0 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.3 1.0 GO:2000977 regulation of mitotic cell cycle, embryonic(GO:0009794) midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) mitotic cell cycle, embryonic(GO:0045448) regulation of timing of neuron differentiation(GO:0060164) regulation of forebrain neuron differentiation(GO:2000977)
0.3 3.0 GO:0030238 male sex determination(GO:0030238)
0.3 1.0 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.3 1.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 0.3 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.3 8.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 3.1 GO:0015886 heme transport(GO:0015886)
0.3 9.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.3 3.0 GO:0070836 caveola assembly(GO:0070836)
0.3 3.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.3 20.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 1.1 GO:0021564 vagus nerve development(GO:0021564)
0.3 0.5 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.3 0.5 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 2.0 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 1.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 1.7 GO:0032808 lacrimal gland development(GO:0032808)
0.2 9.4 GO:0043277 apoptotic cell clearance(GO:0043277)
0.2 0.7 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2 1.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 11.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.2 0.9 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.2 21.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.7 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.2 14.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.2 3.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 1.4 GO:0006642 triglyceride mobilization(GO:0006642) plasma membrane long-chain fatty acid transport(GO:0015911)
0.2 2.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 1.0 GO:0042631 cellular response to water deprivation(GO:0042631)
0.2 3.4 GO:0035855 megakaryocyte development(GO:0035855)
0.2 3.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.2 0.6 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 0.5 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2 8.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 1.8 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.2 2.9 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.2 2.4 GO:0009435 NAD biosynthetic process(GO:0009435)
0.2 0.5 GO:1904954 Spemann organizer formation(GO:0060061) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.2 0.5 GO:0039526 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) modulation by virus of host apoptotic process(GO:0039526) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.2 1.8 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 1.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 1.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 1.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 3.1 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.2 0.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 4.6 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1 2.9 GO:0016180 snRNA processing(GO:0016180)
0.1 1.0 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 2.6 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 3.5 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.1 1.7 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 11.5 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.4 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 10.2 GO:0042100 B cell proliferation(GO:0042100)
0.1 2.1 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.3 GO:0044550 secondary metabolite biosynthetic process(GO:0044550)
0.1 0.4 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 1.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 3.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.0 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.3 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 1.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.3 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.1 5.0 GO:0035904 aorta development(GO:0035904)
0.1 0.8 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 2.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 1.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 2.6 GO:0030252 growth hormone secretion(GO:0030252)
0.1 1.1 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.1 0.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 1.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 7.5 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.1 1.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.3 GO:0010816 neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 1.4 GO:0051764 actin crosslink formation(GO:0051764)
0.1 11.8 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.1 0.3 GO:0002027 regulation of heart rate(GO:0002027)
0.1 1.8 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 1.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 2.4 GO:0006308 DNA catabolic process(GO:0006308)
0.1 9.8 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 8.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 0.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 1.0 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 2.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 2.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.5 GO:0030100 regulation of endocytosis(GO:0030100)
0.1 1.2 GO:0042246 tissue regeneration(GO:0042246)
0.0 3.5 GO:0048678 response to axon injury(GO:0048678)
0.0 2.8 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 2.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 2.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 2.0 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.6 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 2.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 3.4 GO:0016575 histone deacetylation(GO:0016575)
0.0 2.0 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0044546 NLRP3 inflammasome complex assembly(GO:0044546)
0.0 3.3 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.2 GO:0099624 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0 1.3 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 2.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.8 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 1.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.4 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858)
0.0 0.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 2.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 2.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.9 GO:1901998 toxin transport(GO:1901998)
0.0 4.4 GO:0051170 nuclear import(GO:0051170)
0.0 0.3 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0019359 nicotinamide nucleotide biosynthetic process(GO:0019359) pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.9 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.9 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) negative regulation of leukocyte proliferation(GO:0070664)
0.0 1.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 3.9 GO:0006364 rRNA processing(GO:0006364)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 2.3 GO:0006909 phagocytosis(GO:0006909)
0.0 1.1 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 19.6 GO:0070435 Shc-EGFR complex(GO:0070435)
2.9 8.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
2.4 9.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
2.2 6.5 GO:0005608 laminin-3 complex(GO:0005608)
2.1 14.4 GO:0019815 B cell receptor complex(GO:0019815)
2.0 5.9 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
1.2 8.5 GO:0061617 MICOS complex(GO:0061617)
1.1 20.0 GO:0034709 methylosome(GO:0034709)
1.0 4.9 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.8 6.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.8 4.6 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.7 4.5 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.7 3.6 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.7 3.6 GO:0005726 perichromatin fibrils(GO:0005726) interchromatin granule(GO:0035061)
0.7 4.2 GO:0032009 early phagosome(GO:0032009)
0.7 2.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.5 12.8 GO:0005861 troponin complex(GO:0005861)
0.5 4.8 GO:0042587 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.5 3.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.4 20.1 GO:0019814 immunoglobulin complex(GO:0019814)
0.4 1.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.3 12.0 GO:0032420 stereocilium(GO:0032420)
0.3 1.6 GO:0060091 kinocilium(GO:0060091)
0.3 4.2 GO:0042555 MCM complex(GO:0042555)
0.3 2.9 GO:0032039 integrator complex(GO:0032039)
0.3 6.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.3 7.7 GO:0016580 Sin3 complex(GO:0016580)
0.3 6.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.3 1.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 3.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 5.8 GO:0042599 lamellar body(GO:0042599)
0.3 20.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 2.4 GO:0061574 ASAP complex(GO:0061574)
0.3 15.5 GO:0045171 intercellular bridge(GO:0045171)
0.3 14.1 GO:0005801 cis-Golgi network(GO:0005801)
0.3 1.5 GO:0032010 phagolysosome(GO:0032010)
0.2 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891) calcium channel complex(GO:0034704)
0.2 8.2 GO:0000421 autophagosome membrane(GO:0000421)
0.2 4.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 0.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 3.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 19.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 8.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 11.8 GO:0000502 proteasome complex(GO:0000502)
0.2 1.1 GO:0097452 GAIT complex(GO:0097452)
0.1 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 16.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.0 GO:0044194 cytolytic granule(GO:0044194) phagocytic vesicle lumen(GO:0097013)
0.1 3.3 GO:0046930 pore complex(GO:0046930)
0.1 18.6 GO:0016605 PML body(GO:0016605)
0.1 7.3 GO:0002102 podosome(GO:0002102)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.1 GO:0031105 septin complex(GO:0031105)
0.1 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 8.1 GO:0031672 A band(GO:0031672)
0.1 11.4 GO:0035579 specific granule membrane(GO:0035579)
0.1 3.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 13.4 GO:0072562 blood microparticle(GO:0072562)
0.1 1.8 GO:0032433 filopodium tip(GO:0032433)
0.1 4.6 GO:1990391 DNA repair complex(GO:1990391)
0.1 1.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 2.9 GO:0008305 integrin complex(GO:0008305)
0.1 1.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 5.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 3.1 GO:0045178 basal part of cell(GO:0045178)
0.1 5.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 5.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 3.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 5.2 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.7 GO:0001741 XY body(GO:0001741)
0.1 4.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.8 GO:0005771 multivesicular body(GO:0005771)
0.1 1.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 5.0 GO:0005604 basement membrane(GO:0005604)
0.1 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 3.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 5.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 3.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 9.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.5 GO:0012505 endomembrane system(GO:0012505)
0.0 2.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.0 3.4 GO:0034774 secretory granule lumen(GO:0034774)
0.0 2.7 GO:0005901 caveola(GO:0005901)
0.0 5.2 GO:0001726 ruffle(GO:0001726)
0.0 0.9 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 2.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 3.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 8.3 GO:0005813 centrosome(GO:0005813)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
3.5 14.1 GO:0005046 KDEL sequence binding(GO:0005046)
3.3 20.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
3.3 13.1 GO:0032217 riboflavin transporter activity(GO:0032217)
2.8 19.6 GO:0048408 epidermal growth factor binding(GO:0048408)
2.0 10.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.8 7.2 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
1.8 5.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.4 4.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.4 4.2 GO:0045322 unmethylated CpG binding(GO:0045322)
1.2 4.6 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
1.2 4.6 GO:0004774 succinate-CoA ligase activity(GO:0004774)
1.1 3.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
1.0 4.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.0 5.0 GO:0004111 creatine kinase activity(GO:0004111)
1.0 5.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.0 2.9 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
1.0 2.9 GO:0032427 GBD domain binding(GO:0032427)
0.9 3.6 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.9 3.6 GO:0004998 transferrin receptor activity(GO:0004998)
0.9 3.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.9 3.5 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.9 3.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.8 6.1 GO:0001849 complement component C1q binding(GO:0001849)
0.8 13.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.7 2.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.7 12.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.7 2.8 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.7 19.4 GO:0008301 DNA binding, bending(GO:0008301)
0.7 9.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.7 9.3 GO:0031014 troponin T binding(GO:0031014)
0.7 2.6 GO:0016499 orexin receptor activity(GO:0016499)
0.6 2.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.6 1.7 GO:0070644 vitamin D response element binding(GO:0070644)
0.6 3.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.5 7.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.5 8.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.5 3.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.5 2.6 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.5 2.9 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.5 8.4 GO:0035497 cAMP response element binding(GO:0035497)
0.5 1.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 9.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 6.3 GO:0008527 taste receptor activity(GO:0008527)
0.4 13.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 3.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 20.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 3.3 GO:0015288 porin activity(GO:0015288)
0.4 11.2 GO:0005123 death receptor binding(GO:0005123)
0.3 2.8 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.3 1.0 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.3 9.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 9.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 3.1 GO:0015232 heme transporter activity(GO:0015232)
0.3 4.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3 6.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 1.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.3 29.0 GO:0005518 collagen binding(GO:0005518)
0.3 1.2 GO:0043237 laminin-1 binding(GO:0043237)
0.3 5.2 GO:0019864 IgG binding(GO:0019864)
0.3 1.7 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.3 3.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 1.4 GO:0070697 activin receptor binding(GO:0070697)
0.3 1.8 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 4.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 1.7 GO:0019863 IgE binding(GO:0019863)
0.2 1.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.7 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 6.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 1.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 1.8 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.2 1.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 1.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 3.3 GO:0005522 profilin binding(GO:0005522)
0.2 5.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 5.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 3.0 GO:0043295 glutathione binding(GO:0043295)
0.2 0.5 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.2 1.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 2.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 1.5 GO:0043426 MRF binding(GO:0043426)
0.2 1.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 7.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 4.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 0.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.2 6.6 GO:0050699 WW domain binding(GO:0050699)
0.1 1.5 GO:0036310 annealing helicase activity(GO:0036310)
0.1 3.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.9 GO:0030492 hemoglobin binding(GO:0030492)
0.1 20.9 GO:0003823 antigen binding(GO:0003823)
0.1 3.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 4.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 2.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 5.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 1.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 4.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 1.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 1.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 2.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 3.0 GO:0001848 complement binding(GO:0001848)
0.1 2.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 4.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 4.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 2.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.3 GO:0005109 frizzled binding(GO:0005109)
0.1 9.1 GO:0032947 protein complex scaffold(GO:0032947)
0.1 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 1.8 GO:0042166 acetylcholine binding(GO:0042166)
0.1 7.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 1.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 5.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 14.6 GO:0019887 protein kinase regulator activity(GO:0019887)
0.1 7.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 4.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 4.8 GO:0019003 GDP binding(GO:0019003)
0.1 3.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 2.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.3 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 3.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 5.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 4.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 1.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 2.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 2.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.0 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 9.2 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 1.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 2.6 GO:0004386 helicase activity(GO:0004386)
0.0 1.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 4.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.0 1.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 2.3 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 10.6 GO:0005198 structural molecule activity(GO:0005198)
0.0 2.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 19.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.5 7.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.4 12.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.4 13.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.4 5.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.4 19.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 16.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 4.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.3 3.6 PID IL1 PATHWAY IL1-mediated signaling events
0.3 12.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 6.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 8.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 14.3 PID BCR 5PATHWAY BCR signaling pathway
0.2 7.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 9.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.2 PID BMP PATHWAY BMP receptor signaling
0.1 10.0 PID AP1 PATHWAY AP-1 transcription factor network
0.1 5.7 PID ATR PATHWAY ATR signaling pathway
0.1 22.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 4.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 4.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 4.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 2.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 25.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 6.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 9.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 3.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 19.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.8 9.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.7 9.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.6 37.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.5 13.0 REACTOME KINESINS Genes involved in Kinesins
0.5 20.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4 6.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 15.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 10.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.3 6.7 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.3 5.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 13.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3 4.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 12.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.3 9.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3 7.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.3 4.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 1.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 5.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 17.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 4.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 3.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 4.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 3.9 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 4.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 4.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 15.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 4.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 3.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 8.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 2.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 3.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 10.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 2.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 2.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 1.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 5.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.8 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 3.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 2.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 2.3 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 4.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 2.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.0 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 2.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors