averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
ELF2 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000109381.15	E74 like ETS transcription factor 2
GABPA Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000154727.6	GA binding protein transcription factor subunit alpha
ELF5 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000135374.5	E74 like ETS transcription factor 5

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ELF2	hg19_v2_chr4_-_140005443_140005650	0.39	3.4e-09	Click!
ELF5	hg19_v2_chr11_-_34535332_34535352	-0.32	1.3e-06	Click!
GABPA	hg19_v2_chr21_+_27107672_27107698	0.30	5.7e-06	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_+_32687971 Show fit	250.23	ENST00000373586.1	EIF3I Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3, subunit I
chr20_-_49575058 Show fit	227.86	ENST00000371584.4 ENST00000371583.5 ENST00000413082.1	DPM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr12_-_110888103 Show fit	205.96	ENST00000426440.1 ENST00000228825.7	ARPC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin related protein 2/3 complex, subunit 3, 21kDa
chr14_-_69864993 Show fit	203.36	ENST00000555373.1	ERH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enhancer of rudimentary homolog (Drosophila)
chr2_-_73964447 Show fit	198.19	ENST00000272424.5 ENST00000409716.2 ENST00000318190.7	TPRKB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TP53RK binding protein
chr12_+_69080734 Show fit	184.07	ENST00000378905.2	NUP107 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 107kDa
chr1_+_40506392 Show fit	163.00	ENST00000414893.1 ENST00000414281.1 ENST00000420216.1 ENST00000372792.2 ENST00000372798.1 ENST00000340450.3 ENST00000372805.3 ENST00000435719.1 ENST00000427843.1 ENST00000417287.1 ENST00000424977.1 ENST00000446031.1	CAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CAP, adenylate cyclase-associated protein 1 (yeast)
chr7_+_141438393 Show fit	155.66	ENST00000484178.1 ENST00000473783.1 ENST00000481508.1	SSBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	single-stranded DNA binding protein 1, mitochondrial
chr5_+_110074685 Show fit	154.37	ENST00000355943.3 ENST00000447245.2	SLC25A46 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25, member 46
chr19_-_10450287 Show fit	150.78	ENST00000589261.1 ENST00000590569.1 ENST00000589580.1 ENST00000589249.1	ICAM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	intercellular adhesion molecule 3
chr20_-_2451395 Show fit	150.40	ENST00000339610.6 ENST00000381342.2 ENST00000438552.2	SNRPB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptides B and B1
chr10_+_12238171 Show fit	142.39	ENST00000378900.2 ENST00000442050.1	CDC123 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 123
chr13_-_31191642 Show fit	142.10	ENST00000405805.1	HMGB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group box 1
chr18_+_657733 Show fit	138.60	ENST00000323250.5 ENST00000323224.7	TYMS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thymidylate synthetase
chr20_-_49575081 Show fit	136.74	ENST00000371588.5 ENST00000371582.4	DPM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr7_-_5569588 Show fit	133.94	ENST00000417101.1	ACTB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin, beta
chr2_+_198380763 Show fit	133.60	ENST00000448447.2 ENST00000409360.1	MOB4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MOB family member 4, phocein
chr2_+_65454863 Show fit	132.38	ENST00000260641.5	ACTR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ARP2 actin-related protein 2 homolog (yeast)
chr3_-_131221790 Show fit	131.73	ENST00000512877.1 ENST00000264995.3 ENST00000511168.1 ENST00000425847.2	MRPL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L3
chr22_-_36924944 Show fit	131.70	ENST00000405442.1 ENST00000402116.1	EIF3D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3, subunit D
chr7_-_7680601 Show fit	131.55	ENST00000396682.2	RPA3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	replication protein A3, 14kDa
chr22_+_24951436 Show fit	131.53	ENST00000215829.3	SNRPD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr1_+_203830703 Show fit	129.90	ENST00000414487.2	SNRPE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptide E
chr22_-_36925186 Show fit	129.79	ENST00000541106.1 ENST00000455547.1 ENST00000432675.1	EIF3D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3, subunit D
chr1_+_40505891 Show fit	128.01	ENST00000372797.3 ENST00000372802.1 ENST00000449311.1	CAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CAP, adenylate cyclase-associated protein 1 (yeast)
chr2_+_65454926 Show fit	127.68	ENST00000542850.1 ENST00000377982.4	ACTR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ARP2 actin-related protein 2 homolog (yeast)
chr11_-_67169253 Show fit	126.47	ENST00000527663.1 ENST00000312989.7	PPP1CA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, catalytic subunit, alpha isozyme
chr11_-_67169265 Show fit	125.84	ENST00000358239.4 ENST00000376745.4	PPP1CA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, catalytic subunit, alpha isozyme
chr10_-_43892668 Show fit	123.16	ENST00000544000.1	HNRNPF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr10_+_43278217 Show fit	120.88	ENST00000374518.5	BMS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BMS1 ribosome biogenesis factor
chr10_+_12237924 Show fit	120.74	ENST00000429258.2 ENST00000281141.4	CDC123 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 123
chrX_-_153775426 Show fit	120.64	ENST00000393562.2	G6PD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glucose-6-phosphate dehydrogenase
chr2_-_37458749 Show fit	120.13	ENST00000234170.5	CEBPZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CCAAT/enhancer binding protein (C/EBP), zeta
chr5_+_167913450 Show fit	118.72	ENST00000231572.3 ENST00000538719.1	RARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	arginyl-tRNA synthetase
chr11_+_32605350 Show fit	118.61	ENST00000531120.1 ENST00000524896.1 ENST00000323213.5	EIF3M Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3, subunit M
chr4_+_71554196 Show fit	117.14	ENST00000254803.2	UTP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr1_+_84944926 Show fit	117.02	ENST00000370656.1 ENST00000370654.5	RPF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosome production factor 1 homolog (S. cerevisiae)
chr17_+_57784997 Show fit	116.39	ENST00000537567.1 ENST00000539763.1 ENST00000587945.1 ENST00000536180.1 ENST00000589823.2 ENST00000592106.1 ENST00000591315.1 ENST00000545362.1	VMP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuole membrane protein 1
chr2_-_230786619 Show fit	116.17	ENST00000389045.3 ENST00000409677.1	TRIP12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 12
chr2_-_99952769 Show fit	115.70	ENST00000409434.1 ENST00000434323.1 ENST00000264255.3	TXNDC9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thioredoxin domain containing 9
chr14_+_35761580 Show fit	115.70	ENST00000553809.1 ENST00000555764.1 ENST00000556506.1	PSMA6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 6
chr11_+_75110530 Show fit	115.59	ENST00000531188.1 ENST00000530164.1 ENST00000422465.2 ENST00000278572.6 ENST00000534440.1 ENST00000527446.1 ENST00000526608.1 ENST00000527273.1 ENST00000524851.1	RPS3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S3
chr21_-_33984888 Show fit	114.14	ENST00000382549.4 ENST00000540881.1	C21orf59 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 21 open reading frame 59
chr21_-_33985127 Show fit	113.96	ENST00000290155.3	C21orf59 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 21 open reading frame 59
chr5_-_140700322 Show fit	113.64	ENST00000313368.5	TAF7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr11_-_64084959 Show fit	113.52	ENST00000535750.1 ENST00000535126.1 ENST00000539854.1 ENST00000308774.2	TRMT112 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr1_-_165738072 Show fit	112.73	ENST00000481278.1	TMCO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane and coiled-coil domains 1
chr10_-_43904235 Show fit	111.88	ENST00000356053.3	HNRNPF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr11_-_64085533 Show fit	111.75	ENST00000544844.1	TRMT112 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr20_+_16710606 Show fit	111.66	ENST00000377943.5 ENST00000246071.6	SNRPB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptide B
chr1_+_93811438 Show fit	111.53	ENST00000370272.4 ENST00000370267.1	DR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr21_-_33984865 Show fit	111.30	ENST00000458138.1	C21orf59 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 21 open reading frame 59
chr19_+_13261216 Show fit	111.05	ENST00000587885.1 ENST00000292433.3	IER2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	immediate early response 2
chr12_+_69979113 Show fit	110.63	ENST00000299300.6	CCT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chaperonin containing TCP1, subunit 2 (beta)
chr21_-_33984456 Show fit	110.00	ENST00000431216.1 ENST00000553001.1 ENST00000440966.1	AP000275.65 Links Ensembl NCBI GeneCards UniProt NextProt Show fit C21orf59 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Uncharacterized protein chromosome 21 open reading frame 59
chr7_+_141438118 Show fit	109.76	ENST00000265304.6 ENST00000498107.1 ENST00000467681.1 ENST00000465582.1 ENST00000463093.1	SSBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	single-stranded DNA binding protein 1, mitochondrial
chr17_-_57784755 Show fit	109.48	ENST00000537860.1 ENST00000393038.2 ENST00000409433.2	PTRH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peptidyl-tRNA hydrolase 2
chr16_+_30087288 Show fit	109.04	ENST00000279387.7 ENST00000562664.1 ENST00000562222.1	PPP4C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 4, catalytic subunit
chr19_-_51875894 Show fit	109.03	ENST00000600427.1 ENST00000595217.1 ENST00000221978.5	NKG7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	natural killer cell group 7 sequence
chr8_-_55014415 Show fit	108.27	ENST00000522007.1 ENST00000521898.1 ENST00000518546.1 ENST00000316963.3	LYPLA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysophospholipase I
chr3_-_186524234 Show fit	108.09	ENST00000418288.1 ENST00000296273.2	RFC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	replication factor C (activator 1) 4, 37kDa
chr14_+_35761540 Show fit	107.49	ENST00000261479.4	PSMA6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 6
chr12_-_112856623 Show fit	107.43	ENST00000551291.2	RPL6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L6
chr2_+_118572226 Show fit	107.22	ENST00000263239.2	DDX18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr3_-_64009102 Show fit	107.16	ENST00000478185.1 ENST00000482510.1 ENST00000497323.1 ENST00000492933.1 ENST00000295901.4	PSMD6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr17_-_8113542 Show fit	106.69	ENST00000578549.1 ENST00000535053.1 ENST00000582368.1	AURKB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aurora kinase B
chr11_+_62529008 Show fit	106.57	ENST00000301788.7 ENST00000533442.1	POLR2G Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide G
chr6_-_31704282 Show fit	106.46	ENST00000375784.3 ENST00000375779.2	CLIC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride intracellular channel 1
chr6_-_31926629 Show fit	104.93	ENST00000375425.5 ENST00000426722.1 ENST00000441998.1 ENST00000444811.2 ENST00000375429.3	NELFE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	negative elongation factor complex member E
chr1_-_155990580 Show fit	104.88	ENST00000531917.1 ENST00000480567.1 ENST00000526212.1 ENST00000529008.1 ENST00000496742.1 ENST00000295702.4	SSR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal sequence receptor, beta (translocon-associated protein beta)
chr5_+_892745 Show fit	104.39	ENST00000166345.3	TRIP13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 13
chr7_+_5085452 Show fit	103.50	ENST00000353796.3 ENST00000396912.1 ENST00000396904.2	RBAK Links Ensembl NCBI GeneCards UniProt NextProt Show fit RBAK-RBAKDN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RB-associated KRAB zinc finger RBAK-RBAKDN readthrough
chr11_+_65770227 Show fit	103.39	ENST00000527348.1	BANF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	barrier to autointegration factor 1
chr11_-_58345569 Show fit	102.48	ENST00000528954.1 ENST00000528489.1	LPXN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leupaxin
chr10_-_43904608 Show fit	102.42	ENST00000337970.3	HNRNPF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr18_+_3247413 Show fit	102.28	ENST00000579226.1 ENST00000217652.3	MYL12A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 12A, regulatory, non-sarcomeric
chr22_+_24951949 Show fit	101.82	ENST00000402849.1	SNRPD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr19_+_30097181 Show fit	100.84	ENST00000586420.1 ENST00000221770.3 ENST00000392279.3 ENST00000590688.1	POP4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
chrX_+_118602363 Show fit	100.65	ENST00000317881.8	SLC25A5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr14_+_57735614 Show fit	99.74	ENST00000261558.3	AP5M1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 5, mu 1 subunit
chr6_-_31510181 Show fit	99.71	ENST00000458640.1 ENST00000396172.1 ENST00000417556.2	DDX39B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr17_+_57784826 Show fit	99.11	ENST00000262291.4	VMP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuole membrane protein 1
chr5_+_271752 Show fit	98.79	ENST00000505221.1 ENST00000509581.1 ENST00000507528.1	PDCD6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	programmed cell death 6
chr11_+_65769946 Show fit	98.06	ENST00000533166.1	BANF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	barrier to autointegration factor 1
chr20_+_3190006 Show fit	96.52	ENST00000380113.3 ENST00000455664.2 ENST00000399838.3	ITPA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr3_-_49142504 Show fit	96.42	ENST00000306125.6 ENST00000420147.2	QARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutaminyl-tRNA synthetase
chr19_+_50180317 Show fit	95.64	ENST00000534465.1	PRMT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein arginine methyltransferase 1
chr6_-_31509714 Show fit	95.53	ENST00000456662.1 ENST00000431908.1 ENST00000456976.1 ENST00000428450.1 ENST00000453105.2 ENST00000418897.1 ENST00000415382.2 ENST00000449074.2 ENST00000419020.1 ENST00000428098.1	DDX39B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr8_-_121457332 Show fit	95.52	ENST00000518918.1	MRPL13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L13
chr18_+_3247779 Show fit	94.72	ENST00000578611.1 ENST00000583449.1	MYL12A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 12A, regulatory, non-sarcomeric
chr14_-_71107921 Show fit	94.28	ENST00000553982.1 ENST00000500016.1	CTD-2540L5.5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit CTD-2540L5.6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CTD-2540L5.5 CTD-2540L5.6
chr3_-_119396193 Show fit	93.91	ENST00000484810.1 ENST00000497116.1 ENST00000261070.2	COX17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COX17 cytochrome c oxidase copper chaperone
chr1_-_20987889 Show fit	93.47	ENST00000415136.2	DDOST Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr1_-_153518270 Show fit	93.34	ENST00000354332.4 ENST00000368716.4	S100A4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	S100 calcium binding protein A4
chr19_+_35645618 Show fit	92.50	ENST00000392218.2 ENST00000543307.1 ENST00000392219.2 ENST00000541435.2 ENST00000590686.1 ENST00000342879.3 ENST00000588699.1	FXYD5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 5
chr3_-_49142178 Show fit	92.01	ENST00000452739.1 ENST00000414533.1 ENST00000417025.1	QARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutaminyl-tRNA synthetase
chr4_-_100815525 Show fit	91.64	ENST00000226522.8 ENST00000499666.2	LAMTOR3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr6_-_41909191 Show fit	91.48	ENST00000512426.1 ENST00000372987.4	CCND3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin D3
chrX_+_21958814 Show fit	91.46	ENST00000379404.1 ENST00000415881.2	SMS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermine synthase
chr2_-_55496174 Show fit	91.31	ENST00000417363.1 ENST00000412530.1 ENST00000394600.3 ENST00000366137.2 ENST00000420637.1	MTIF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial translational initiation factor 2
chr15_+_78833105 Show fit	91.26	ENST00000558341.1 ENST00000559437.1	PSMA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr2_+_201936707 Show fit	90.54	ENST00000433898.1 ENST00000454214.1	NDUFB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr11_-_14541872 Show fit	90.35	ENST00000419365.2 ENST00000530457.1 ENST00000532256.1 ENST00000533068.1	PSMA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 1
chr16_-_30204987 Show fit	89.93	ENST00000569282.1 ENST00000567436.1	BOLA2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	bolA family member 2B
chr15_-_65282232 Show fit	89.75	ENST00000416889.2	SPG21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr17_+_1944790 Show fit	89.63	ENST00000575162.1	DPH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	diphthamide biosynthesis 1
chr16_-_67969888 Show fit	89.49	ENST00000574576.2	PSMB10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 10
chr12_+_7079944 Show fit	89.21	ENST00000261406.6	EMG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EMG1 N1-specific pseudouridine methyltransferase
chr19_-_45927622 Show fit	88.84	ENST00000300853.3 ENST00000589165.1	ERCC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr15_+_78833071 Show fit	88.57	ENST00000559365.1	PSMA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr11_-_64013288 Show fit	88.53	ENST00000542235.1	PPP1R14B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_88070920 Show fit	88.35	ENST00000524463.1 ENST00000227266.5	CTSC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cathepsin C
chr6_-_32812420 Show fit	88.21	ENST00000374881.2	PSMB8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 8
chr3_+_151986709 Show fit	88.09	ENST00000495875.2 ENST00000493459.1 ENST00000324210.5 ENST00000459747.1	MBNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	muscleblind-like splicing regulator 1
chr18_+_19192228 Show fit	87.84	ENST00000300413.5 ENST00000579618.1 ENST00000582475.1	SNRPD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr6_-_2842087 Show fit	87.66	ENST00000537185.1	SERPINB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr19_-_10446449 Show fit	87.40	ENST00000592439.1	ICAM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	intercellular adhesion molecule 3
chr19_+_9938562 Show fit	87.15	ENST00000586895.1 ENST00000358666.3 ENST00000590068.1 ENST00000593087.1	UBL5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-like 5
chr4_+_41937131 Show fit	86.85	ENST00000504986.1 ENST00000508448.1 ENST00000513702.1 ENST00000325094.5	TMEM33 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 33
chr1_+_24018269 Show fit	86.57	ENST00000374550.3	RPL11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L11
chr1_+_40723779 Show fit	86.39	ENST00000372759.3	ZMPSTE24 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc metallopeptidase STE24
chr8_-_67974552 Show fit	85.11	ENST00000357849.4	COPS5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COP9 signalosome subunit 5
chr1_-_20987851 Show fit	84.92	ENST00000464364.1 ENST00000602624.2	DDOST Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr2_+_201754050 Show fit	84.83	ENST00000426253.1 ENST00000416651.1 ENST00000454952.1 ENST00000409020.1 ENST00000359683.4	NIF3L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chrX_+_100646190 Show fit	84.63	ENST00000471855.1	RPL36A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L36a
chr19_+_35645817 Show fit	84.14	ENST00000423817.3	FXYD5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 5
chr7_+_102988082 Show fit	83.77	ENST00000292644.3 ENST00000544811.1	PSMC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr1_-_43638168 Show fit	83.54	ENST00000431635.2	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EBNA1 binding protein 2
chr16_-_12009833 Show fit	83.39	ENST00000420576.2	GSPT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G1 to S phase transition 1
chr20_+_388935 Show fit	83.25	ENST00000382181.2 ENST00000400247.3	RBCK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RanBP-type and C3HC4-type zinc finger containing 1
chr10_-_27443155 Show fit	83.06	ENST00000427324.1 ENST00000326799.3	YME1L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	YME1-like 1 ATPase
chr2_-_55496344 Show fit	83.04	ENST00000403721.1 ENST00000263629.4	MTIF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial translational initiation factor 2
chr6_+_30035307 Show fit	83.04	ENST00000376765.2 ENST00000376763.1	PPP1R11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 11
chr11_+_65769550 Show fit	82.88	ENST00000312175.2 ENST00000445560.2 ENST00000530204.1	BANF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	barrier to autointegration factor 1
chr12_+_69979210 Show fit	82.86	ENST00000544368.2	CCT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chaperonin containing TCP1, subunit 2 (beta)
chr12_-_112847108 Show fit	82.81	ENST00000549847.1	RPL6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L6
chr3_+_160117087 Show fit	82.56	ENST00000357388.3	SMC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 4
chr11_-_65655906 Show fit	82.31	ENST00000533045.1 ENST00000338369.2 ENST00000357519.4	FIBP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibroblast growth factor (acidic) intracellular binding protein
chr15_-_65282274 Show fit	82.09	ENST00000204566.2	SPG21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr15_-_101835110 Show fit	81.95	ENST00000560496.1	SNRPA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptide A'
chr6_-_32811771 Show fit	81.65	ENST00000395339.3 ENST00000374882.3	PSMB8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 8
chr3_-_133380731 Show fit	81.45	ENST00000260810.5	TOPBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	topoisomerase (DNA) II binding protein 1
chr11_-_64013663 Show fit	81.10	ENST00000392210.2	PPP1R14B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_+_201754135 Show fit	81.01	ENST00000409357.1 ENST00000409129.2	NIF3L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr12_-_66563786 Show fit	80.77	ENST00000542724.1	TMBIM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane BAX inhibitor motif containing 4
chr15_+_78832747 Show fit	80.71	ENST00000560217.1 ENST00000044462.7 ENST00000559082.1 ENST00000559948.1 ENST00000413382.2 ENST00000559146.1 ENST00000558281.1	PSMA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr10_+_51371390 Show fit	80.47	ENST00000478381.1 ENST00000451577.2 ENST00000374098.2 ENST00000374097.2	TIMM23B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr5_-_140070897 Show fit	80.28	ENST00000448240.1 ENST00000438307.2 ENST00000415192.2 ENST00000457527.2 ENST00000307633.3 ENST00000507746.1 ENST00000431330.2	HARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histidyl-tRNA synthetase
chr8_-_55014336 Show fit	79.86	ENST00000343231.6	LYPLA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysophospholipase I
chr9_+_116037922 Show fit	79.43	ENST00000374198.4	PRPF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pre-mRNA processing factor 4
chr7_+_30634297 Show fit	79.19	ENST00000389266.3	GARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glycyl-tRNA synthetase
chr22_-_29949634 Show fit	79.12	ENST00000397872.1 ENST00000397871.1 ENST00000440771.1	THOC5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	THO complex 5
chr12_-_498620 Show fit	79.04	ENST00000399788.2 ENST00000382815.4	KDM5A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine (K)-specific demethylase 5A
chr17_+_73008755 Show fit	78.65	ENST00000584208.1 ENST00000301585.5	ICT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	immature colon carcinoma transcript 1
chr5_-_150284351 Show fit	78.07	ENST00000427179.1	ZNF300 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 300
chr7_+_99006550 Show fit	78.02	ENST00000222969.5	BUD31 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BUD31 homolog (S. cerevisiae)
chr16_-_85833160 Show fit	77.99	ENST00000435200.2	EMC8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ER membrane protein complex subunit 8
chr4_-_10118348 Show fit	77.57	ENST00000502702.1	WDR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 1
chr6_+_32811885 Show fit	77.37	ENST00000458296.1 ENST00000413039.1 ENST00000429600.1 ENST00000412095.1 ENST00000415067.1 ENST00000395330.1	TAPSAR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit PSMB9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAP1 and PSMB8 antisense RNA 1 proteasome (prosome, macropain) subunit, beta type, 9
chr5_+_271733 Show fit	76.51	ENST00000264933.4	PDCD6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	programmed cell death 6
chr21_-_46340884 Show fit	76.17	ENST00000302347.5 ENST00000517819.1	ITGB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr3_+_142720366 Show fit	76.03	ENST00000493782.1 ENST00000397933.2 ENST00000473835.2 ENST00000493598.2	U2SURP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	U2 snRNP-associated SURP domain containing
chr7_-_99698338 Show fit	75.92	ENST00000354230.3 ENST00000425308.1	MCM7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 7
chr10_+_75504105 Show fit	75.89	ENST00000535742.1 ENST00000546025.1 ENST00000345254.4 ENST00000540668.1 ENST00000339365.2 ENST00000411652.2	SEC24C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEC24 family member C
chr15_-_64455404 Show fit	75.30	ENST00000300026.3	PPIB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peptidylprolyl isomerase B (cyclophilin B)
chr16_-_29465668 Show fit	75.27	ENST00000569622.1	RP11-345J4.5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BolA-like protein 2
chr1_-_63988846 Show fit	75.19	ENST00000283568.8 ENST00000371092.3 ENST00000271002.10	ITGB3BP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin beta 3 binding protein (beta3-endonexin)
chr6_+_30034865 Show fit	74.88	ENST00000376772.3	PPP1R11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 11
chr4_-_120988229 Show fit	74.77	ENST00000296509.6	MAD2L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MAD2 mitotic arrest deficient-like 1 (yeast)
chr1_+_24019099 Show fit	74.44	ENST00000443624.1 ENST00000458455.1	RPL11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L11
chr4_-_10118573 Show fit	74.23	ENST00000382452.2 ENST00000382451.2	WDR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 1
chr5_+_68530668 Show fit	74.10	ENST00000506563.1	CDK7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 7
chr7_-_54826920 Show fit	73.90	ENST00000395535.3 ENST00000352861.4	SEC61G Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Sec61 gamma subunit
chr2_+_122494676 Show fit	73.79	ENST00000455432.1	TSN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	translin
chr15_+_75074410 Show fit	73.62	ENST00000439220.2	CSK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	c-src tyrosine kinase
chr11_+_118889142 Show fit	73.50	ENST00000533632.1	TRAPPC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	trafficking protein particle complex 4
chr1_-_108742957 Show fit	73.33	ENST00000565488.1	SLC25A24 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr1_+_32479430 Show fit	73.29	ENST00000327300.7 ENST00000492989.1	KHDRBS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KH domain containing, RNA binding, signal transduction associated 1
chr11_+_118230287 Show fit	73.06	ENST00000252108.3 ENST00000431736.2	UBE4A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitination factor E4A
chr12_+_51632638 Show fit	72.84	ENST00000549732.2	DAZAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DAZ associated protein 2
chr5_-_176778523 Show fit	72.61	ENST00000513877.1 ENST00000515209.1 ENST00000514458.1 ENST00000502560.1	LMAN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lectin, mannose-binding 2
chr14_-_21979428 Show fit	72.09	ENST00000538267.1 ENST00000298717.4	METTL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methyltransferase like 3
chr1_-_159894319 Show fit	72.02	ENST00000320307.4	TAGLN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transgelin 2
chr7_+_44240520 Show fit	71.96	ENST00000496112.1 ENST00000223369.2	YKT6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	YKT6 v-SNARE homolog (S. cerevisiae)
chr15_-_83736091 Show fit	71.92	ENST00000261721.4	BTBD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BTB (POZ) domain containing 1
chr11_-_57298187 Show fit	71.89	ENST00000525158.1 ENST00000257245.4 ENST00000525587.1	TIMM10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of inner mitochondrial membrane 10 homolog (yeast)
chr19_-_10450328 Show fit	71.67	ENST00000160262.5	ICAM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	intercellular adhesion molecule 3
chr15_+_66161802 Show fit	71.49	ENST00000566233.1 ENST00000565075.1 ENST00000435304.2	RAB11A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB11A, member RAS oncogene family
chr20_-_33872518 Show fit	70.49	ENST00000374436.3	EIF6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 6
chr7_-_102119342 Show fit	70.38	ENST00000393794.3 ENST00000292614.5	POLR2J Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr1_-_20987982 Show fit	70.37	ENST00000375048.3	DDOST Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr9_-_88969303 Show fit	70.30	ENST00000277141.6 ENST00000375963.3	ZCCHC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, CCHC domain containing 6
chr7_+_2281843 Show fit	70.28	ENST00000356714.1 ENST00000397049.1	NUDT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr9_-_2844058 Show fit	70.07	ENST00000397885.2	KIAA0020 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA0020
chr12_-_121019165 Show fit	70.00	ENST00000341039.2 ENST00000357500.4	POP5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr2_-_230786679 Show fit	70.00	ENST00000543084.1 ENST00000343290.5 ENST00000389044.4 ENST00000283943.5	TRIP12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 12
chr6_+_22569784 Show fit	70.00	ENST00000510882.2	HDGFL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hepatoma derived growth factor-like 1
chr15_+_44092784 Show fit	69.92	ENST00000458412.1	HYPK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	huntingtin interacting protein K
chr20_-_33872548 Show fit	69.76	ENST00000374443.3	EIF6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 6
chr16_-_85833109 Show fit	69.72	ENST00000253457.3	EMC8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ER membrane protein complex subunit 8

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
92.0	276.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
91.6	274.7	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
75.4	377.2	GO:0019348	dolichol metabolic process(GO:0019348)
72.4	217.3	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
71.5	357.5	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
69.6	208.7	GO:0090149	mitochondrial membrane fission(GO:0090149)
64.8	194.5	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
63.1	252.3	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
62.5	187.4	GO:0006597	spermine biosynthetic process(GO:0006597)
61.8	247.3	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
58.9	176.6	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
58.3	233.2	GO:0006235	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
57.0	171.1	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878)
56.1	224.6	GO:0042247	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
55.8	167.3	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
54.3	271.5	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
53.5	214.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
52.4	209.7	GO:0010796	regulation of multivesicular body size(GO:0010796)
51.3	154.0	GO:1903722	regulation of centriole elongation(GO:1903722)
49.2	49.2	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
49.2	147.5	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
46.3	185.1	GO:0032218	riboflavin transport(GO:0032218)
44.4	177.6	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
41.3	124.0	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
40.3	161.0	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
39.9	159.5	GO:0006203	dGTP catabolic process(GO:0006203)
39.3	275.4	GO:1900045	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
38.7	116.0	GO:0002184	cytoplasmic translational termination(GO:0002184)
38.6	193.1	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
38.1	152.4	GO:0002270	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
37.5	112.5	GO:1902822	regulation of late endosome to lysosome transport(GO:1902822)
36.8	110.4	GO:0015846	polyamine transport(GO:0015846)
36.4	109.3	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
36.4	109.3	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
36.4	218.7	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
35.8	107.4	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
35.4	212.5	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
35.2	176.2	GO:0075525	viral translational termination-reinitiation(GO:0075525)
35.2	211.0	GO:1904431	positive regulation of t-circle formation(GO:1904431)
34.8	34.8	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
34.2	102.5	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
33.9	339.0	GO:0051096	positive regulation of helicase activity(GO:0051096)
33.0	231.1	GO:1903679	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
32.8	131.2	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
32.8	65.6	GO:0046070	dGTP metabolic process(GO:0046070)
32.8	98.4	GO:2001162	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
32.3	129.0	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
32.2	96.7	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
32.2	96.5	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
31.8	190.8	GO:0015866	ADP transport(GO:0015866)
31.8	95.3	GO:0002084	protein depalmitoylation(GO:0002084)
31.6	63.3	GO:0002188	translation reinitiation(GO:0002188)
31.4	503.0	GO:0043248	proteasome assembly(GO:0043248)
31.0	31.0	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
30.1	120.3	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
30.0	89.9	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
29.9	239.6	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
29.7	59.4	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
29.5	118.0	GO:0015960	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
29.5	88.4	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
29.4	88.2	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
29.3	205.1	GO:0016074	snoRNA metabolic process(GO:0016074)
29.1	29.1	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
28.9	115.6	GO:0071461	cellular response to redox state(GO:0071461)
28.8	86.4	GO:0030327	prenylated protein catabolic process(GO:0030327)
28.6	114.3	GO:0006051	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
28.4	85.3	GO:0042256	mature ribosome assembly(GO:0042256)
28.4	255.5	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
28.3	226.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
28.3	1386.4	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
28.2	84.7	GO:0070668	regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
28.1	84.3	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
27.8	27.8	GO:1904868	telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
27.7	83.2	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
27.7	27.7	GO:0006513	protein monoubiquitination(GO:0006513)
27.2	27.2	GO:0036480	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) positive regulation of oxidative stress-induced neuron death(GO:1903223) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
26.2	209.6	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
26.1	130.3	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
25.5	25.5	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
25.1	75.3	GO:1901873	regulation of post-translational protein modification(GO:1901873)
25.0	199.9	GO:0034982	mitochondrial protein processing(GO:0034982)
25.0	2321.9	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
24.9	124.4	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
24.7	49.4	GO:0045903	positive regulation of translational fidelity(GO:0045903)
24.5	24.5	GO:0051126	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
24.4	97.4	GO:0007144	female meiosis I(GO:0007144)
24.3	72.8	GO:0033341	regulation of collagen binding(GO:0033341)
24.3	291.1	GO:0015074	DNA integration(GO:0015074)
24.0	24.0	GO:0071480	cellular response to gamma radiation(GO:0071480)
23.2	139.5	GO:0070475	rRNA base methylation(GO:0070475)
22.6	67.9	GO:0019474	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
22.1	44.1	GO:0043096	purine nucleobase salvage(GO:0043096)
22.0	88.0	GO:0032790	ribosome disassembly(GO:0032790)
21.6	432.6	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
21.3	192.0	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
21.2	169.9	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
21.2	106.0	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
20.9	62.8	GO:1902568	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
20.8	207.8	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
20.7	62.2	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
20.6	164.4	GO:2000210	positive regulation of anoikis(GO:2000210)
20.5	61.6	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
20.3	61.0	GO:0036089	cleavage furrow formation(GO:0036089)
20.3	81.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
20.0	140.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
19.9	59.7	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
19.8	79.0	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
19.6	78.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
19.5	58.6	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
19.5	78.1	GO:0030242	pexophagy(GO:0030242)
19.4	58.2	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
19.3	270.3	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478)
19.2	134.5	GO:1903895	negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
19.2	115.3	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
19.2	57.6	GO:0039513	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
19.2	441.0	GO:0000028	ribosomal small subunit assembly(GO:0000028)
19.2	38.3	GO:1901656	glycoside transport(GO:1901656)
19.1	114.7	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
19.1	95.3	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
18.7	56.0	GO:1902463	protein localization to cell leading edge(GO:1902463)
18.5	18.5	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
18.5	55.5	GO:0046294	formaldehyde catabolic process(GO:0046294)
18.5	74.0	GO:1903298	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
18.4	36.9	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
18.3	182.7	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
18.3	109.6	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
18.1	72.5	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
18.0	269.8	GO:0033523	histone H2B ubiquitination(GO:0033523)
17.9	53.7	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
17.9	17.9	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
17.9	804.9	GO:0009452	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
17.8	17.8	GO:0046102	inosine metabolic process(GO:0046102)
17.5	280.0	GO:0006295	nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
17.4	261.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
17.4	52.2	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
17.3	138.7	GO:0006983	ER overload response(GO:0006983)
17.2	51.7	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
17.1	51.4	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
17.1	342.1	GO:0043101	purine-containing compound salvage(GO:0043101)
17.1	119.7	GO:0045048	protein insertion into ER membrane(GO:0045048)
17.1	51.3	GO:0006624	vacuolar protein processing(GO:0006624)
17.0	17.0	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
17.0	84.8	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
16.8	50.4	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
16.6	83.1	GO:0071964	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
16.5	99.2	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
16.5	66.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
16.4	131.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
16.4	81.8	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
16.3	48.9	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
16.3	260.4	GO:0060546	negative regulation of necroptotic process(GO:0060546)
16.2	16.2	GO:0006404	RNA import into nucleus(GO:0006404)
16.2	64.7	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
16.1	32.2	GO:0032056	positive regulation of translation in response to stress(GO:0032056)
16.1	16.1	GO:0060613	fat pad development(GO:0060613)
16.1	32.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
16.0	79.8	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
15.9	15.9	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
15.8	79.0	GO:0048478	replication fork protection(GO:0048478)
15.8	47.3	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
15.7	47.1	GO:0097327	response to antineoplastic agent(GO:0097327)
15.7	94.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
15.6	78.2	GO:0010710	regulation of collagen catabolic process(GO:0010710)
15.6	31.2	GO:1900368	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
15.6	1464.7	GO:0002181	cytoplasmic translation(GO:0002181)
15.6	171.4	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
15.5	665.7	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
15.4	61.7	GO:0016240	autophagosome docking(GO:0016240)
15.2	76.2	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
15.1	45.4	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
15.0	120.2	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
15.0	254.7	GO:1904872	regulation of telomerase RNA localization to Cajal body(GO:1904872)
14.9	104.6	GO:0006226	dUMP biosynthetic process(GO:0006226)
14.8	59.3	GO:0043335	protein unfolding(GO:0043335)
14.6	73.2	GO:0090151	establishment of protein localization to mitochondrial membrane(GO:0090151)
14.6	102.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
14.6	989.6	GO:0070125	mitochondrial translational elongation(GO:0070125)
14.4	57.5	GO:0071492	cellular response to UV-A(GO:0071492)
14.4	71.9	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
14.3	86.0	GO:2000567	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
14.3	157.4	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
14.2	198.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
14.1	56.4	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
13.9	41.8	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
13.8	41.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
13.8	41.4	GO:0006267	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
13.7	41.2	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
13.7	27.4	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
13.7	218.9	GO:0000338	protein deneddylation(GO:0000338)
13.7	287.0	GO:0045948	positive regulation of translational initiation(GO:0045948)
13.7	95.7	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
13.6	40.9	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
13.6	27.2	GO:1900110	negative regulation of histone H3-K9 dimethylation(GO:1900110)
13.6	68.0	GO:1904798	positive regulation of core promoter binding(GO:1904798)
13.6	68.0	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
13.5	40.6	GO:2000232	positive regulation of ribosome biogenesis(GO:0090070) regulation of rRNA processing(GO:2000232) positive regulation of rRNA processing(GO:2000234)
13.5	1025.1	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
13.3	119.6	GO:0045338	farnesyl diphosphate metabolic process(GO:0045338)
13.2	13.2	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
13.1	52.3	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
13.1	65.3	GO:0018158	protein oxidation(GO:0018158)
12.9	258.8	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
12.8	115.3	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
12.8	51.1	GO:0042278	purine nucleoside metabolic process(GO:0042278)
12.8	38.3	GO:0010286	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
12.7	12.7	GO:0032829	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
12.7	12.7	GO:1903093	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
12.6	126.1	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
12.6	37.8	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
12.6	37.8	GO:1902416	positive regulation of mRNA binding(GO:1902416)
12.6	37.8	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
12.6	37.7	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
12.6	37.7	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
12.5	50.0	GO:0072402	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
12.5	87.5	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
12.4	260.3	GO:0006465	signal peptide processing(GO:0006465)
12.4	37.1	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
12.4	86.5	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
12.3	245.8	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
12.2	12.2	GO:0021997	neural plate axis specification(GO:0021997)
12.2	73.3	GO:1903758	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
12.2	61.1	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
12.2	206.8	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
12.1	60.6	GO:0061085	regulation of histone H3-K27 methylation(GO:0061085)
12.1	121.0	GO:0015939	pantothenate metabolic process(GO:0015939)
12.0	48.1	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
12.0	156.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
11.9	512.3	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
11.8	47.4	GO:0002290	gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
11.8	165.4	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
11.8	35.4	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
11.8	11.8	GO:0051224	negative regulation of protein transport(GO:0051224)
11.8	11.8	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
11.6	11.6	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
11.5	34.6	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
11.5	80.6	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
11.4	22.9	GO:1902966	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
11.4	34.3	GO:0042351	GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
11.4	856.4	GO:0045047	protein targeting to ER(GO:0045047)
11.4	45.5	GO:0046452	dihydrofolate metabolic process(GO:0046452)
11.3	169.5	GO:0006516	glycoprotein catabolic process(GO:0006516)
11.2	44.9	GO:0033182	regulation of histone ubiquitination(GO:0033182)
11.2	22.4	GO:0046292	formaldehyde metabolic process(GO:0046292)
11.2	44.8	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
11.2	33.5	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
11.2	11.2	GO:0042180	cellular ketone metabolic process(GO:0042180)
11.1	66.9	GO:0007386	compartment pattern specification(GO:0007386)
11.1	156.0	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
11.1	77.9	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
11.1	33.3	GO:0051685	maintenance of ER location(GO:0051685)
11.1	166.2	GO:0006415	translational termination(GO:0006415)
11.0	11.0	GO:0070341	fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344) negative regulation of fat cell proliferation(GO:0070345)
10.9	21.9	GO:1904796	regulation of core promoter binding(GO:1904796)
10.9	87.6	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
10.9	32.7	GO:1902544	regulation of DNA N-glycosylase activity(GO:1902544)
10.9	21.8	GO:0071030	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of pre-mRNA at the site of transcription(GO:0071033) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
10.9	43.6	GO:0006740	NADPH regeneration(GO:0006740)
10.9	32.6	GO:1901355	response to rapamycin(GO:1901355)
10.9	130.3	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
10.8	43.3	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
10.8	54.0	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
10.8	118.3	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
10.7	107.4	GO:0031584	activation of phospholipase D activity(GO:0031584)
10.7	10.7	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
10.6	84.9	GO:0001887	selenium compound metabolic process(GO:0001887)
10.6	74.3	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
10.6	392.5	GO:0042407	cristae formation(GO:0042407)
10.6	21.1	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
10.5	168.7	GO:0001682	tRNA 5'-leader removal(GO:0001682)
10.5	84.3	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
10.5	21.1	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
10.5	42.1	GO:0032383	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
10.4	125.3	GO:0000920	cell separation after cytokinesis(GO:0000920)
10.4	51.9	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
10.4	341.9	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
10.4	10.4	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
10.4	31.1	GO:1901253	regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
10.3	51.6	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
10.3	41.3	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
10.3	92.5	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
10.2	726.4	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
10.2	61.2	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
10.0	30.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
10.0	20.0	GO:0001923	B-1 B cell differentiation(GO:0001923)
10.0	49.9	GO:0009440	cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
10.0	29.9	GO:0006167	AMP biosynthetic process(GO:0006167)
9.9	29.7	GO:2000254	male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093) regulation of male germ cell proliferation(GO:2000254)
9.9	39.6	GO:1901804	glucosylceramide catabolic process(GO:0006680) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
9.9	19.7	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
9.7	29.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
9.6	19.1	GO:0003162	atrioventricular node development(GO:0003162)
9.6	38.3	GO:0090170	regulation of Golgi inheritance(GO:0090170)
9.5	38.1	GO:0090385	phagosome-lysosome fusion(GO:0090385)
9.4	217.3	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
9.4	47.2	GO:0015862	uridine transport(GO:0015862)
9.4	28.2	GO:0071421	manganese ion transmembrane transport(GO:0071421)
9.3	37.1	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
9.3	27.8	GO:0061198	fungiform papilla formation(GO:0061198)
9.2	9.2	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
9.2	73.6	GO:0035268	protein mannosylation(GO:0035268)
9.1	36.4	GO:0043366	beta selection(GO:0043366)
9.1	353.5	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
9.1	18.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
9.0	27.0	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
9.0	9.0	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
9.0	9.0	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
9.0	62.9	GO:0072718	response to cisplatin(GO:0072718)
8.9	17.9	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
8.9	26.6	GO:1903973	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
8.9	35.5	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
8.9	79.7	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
8.8	79.3	GO:1902969	mitotic DNA replication(GO:1902969)
8.8	8.8	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212)
8.8	35.2	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
8.8	52.6	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
8.8	87.7	GO:0071044	histone mRNA catabolic process(GO:0071044)
8.8	35.1	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
8.7	34.9	GO:0030047	actin modification(GO:0030047)
8.7	43.3	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
8.6	43.2	GO:0033753	ribosomal subunit export from nucleus(GO:0000054) ribosomal large subunit export from nucleus(GO:0000055) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
8.6	664.5	GO:0006413	translational initiation(GO:0006413)
8.6	17.2	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
8.6	25.7	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
8.5	8.5	GO:2000196	positive regulation of female gonad development(GO:2000196)
8.5	42.6	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
8.5	17.0	GO:0072321	chaperone-mediated protein transport(GO:0072321)
8.5	8.5	GO:0061010	gall bladder development(GO:0061010)
8.5	110.2	GO:0016180	snRNA processing(GO:0016180)
8.5	33.9	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
8.4	25.3	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
8.4	168.7	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
8.4	42.1	GO:2000035	regulation of stem cell division(GO:2000035)
8.4	41.9	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
8.4	58.5	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
8.3	16.7	GO:1901185	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
8.3	8.3	GO:0042700	luteinizing hormone signaling pathway(GO:0042700)
8.3	24.9	GO:0009304	tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
8.3	132.4	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
8.3	49.6	GO:0002638	negative regulation of immunoglobulin production(GO:0002638)
8.2	8.2	GO:0019087	transformation of host cell by virus(GO:0019087)
8.2	49.3	GO:0051013	microtubule severing(GO:0051013)
8.2	106.4	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
8.1	32.6	GO:0051292	nuclear pore complex assembly(GO:0051292)
8.1	560.1	GO:0045454	cell redox homeostasis(GO:0045454)
8.1	145.2	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
8.0	32.1	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
8.0	24.1	GO:0019417	sulfur oxidation(GO:0019417)
8.0	48.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
8.0	40.0	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
8.0	104.0	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
8.0	32.0	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
8.0	318.2	GO:0010501	RNA secondary structure unwinding(GO:0010501)
7.9	7.9	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
7.8	39.2	GO:0044351	macropinocytosis(GO:0044351)
7.8	23.3	GO:0071789	spindle pole body duplication(GO:0030474) nuclear pore distribution(GO:0031081) spindle pole body organization(GO:0051300) nuclear pore localization(GO:0051664) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
7.7	7.7	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
7.7	69.3	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
7.7	23.1	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
7.6	38.1	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016)
7.6	76.2	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
7.6	68.3	GO:0044818	mitotic G2/M transition checkpoint(GO:0044818)
7.5	15.1	GO:0032077	positive regulation of deoxyribonuclease activity(GO:0032077)
7.5	30.0	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
7.5	15.0	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
7.5	22.4	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
7.4	22.3	GO:0002441	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
7.4	119.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
7.4	81.5	GO:0060263	regulation of respiratory burst(GO:0060263)
7.4	44.3	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
7.3	29.3	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
7.3	43.9	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
7.3	21.9	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
7.3	21.9	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
7.3	538.3	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
7.3	43.5	GO:0090161	Golgi ribbon formation(GO:0090161)
7.2	64.7	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
7.2	143.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
7.2	21.5	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
7.1	35.7	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
7.1	135.5	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
7.1	42.7	GO:0036111	very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
7.1	7.1	GO:0070671	response to interleukin-12(GO:0070671)
7.1	35.3	GO:1902903	late endosomal microautophagy(GO:0061738) regulation of fibril organization(GO:1902903)
7.0	14.0	GO:0014900	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
7.0	27.8	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
6.9	48.2	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
6.9	41.3	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
6.8	20.5	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
6.8	20.5	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
6.8	6.8	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
6.8	339.7	GO:0045071	negative regulation of viral genome replication(GO:0045071)
6.8	33.9	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
6.8	74.3	GO:0051601	exocyst localization(GO:0051601)
6.7	20.2	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)
6.7	46.7	GO:0038203	TORC2 signaling(GO:0038203)
6.6	33.0	GO:0009838	abscission(GO:0009838)
6.6	52.8	GO:0051014	actin filament severing(GO:0051014)
6.6	26.3	GO:0010216	maintenance of DNA methylation(GO:0010216)
6.6	6.6	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
6.6	6.6	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
6.5	183.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
6.5	58.7	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
6.5	52.1	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
6.5	6.5	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
6.4	12.9	GO:0045091	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
6.4	6.4	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
6.4	38.6	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
6.3	31.7	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
6.3	69.6	GO:0018345	protein palmitoylation(GO:0018345)
6.3	44.3	GO:0046618	drug export(GO:0046618)
6.3	18.8	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
6.3	50.0	GO:0032506	cytokinetic process(GO:0032506)
6.2	37.5	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
6.2	31.0	GO:0042631	cellular response to water deprivation(GO:0042631)
6.2	37.2	GO:0046898	response to cycloheximide(GO:0046898)
6.2	49.5	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
6.2	12.4	GO:1902570	protein localization to nucleolus(GO:1902570)
6.2	6.2	GO:0040031	snRNA modification(GO:0040031)
6.2	30.8	GO:0090204	protein localization to nuclear pore(GO:0090204)
6.2	12.3	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
6.1	147.4	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
6.1	12.2	GO:0090166	Golgi disassembly(GO:0090166)
6.1	12.2	GO:1903333	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
6.1	67.0	GO:0048308	organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
6.0	6.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
6.0	108.7	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
6.0	11.9	GO:1904925	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
6.0	59.6	GO:0045116	protein neddylation(GO:0045116)
5.9	41.5	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
5.9	473.3	GO:0070527	platelet aggregation(GO:0070527)
5.9	76.6	GO:0097320	membrane tubulation(GO:0097320)
5.9	58.9	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
5.9	23.5	GO:0030259	lipid glycosylation(GO:0030259)
5.9	135.0	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
5.8	52.2	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
5.8	11.6	GO:0002774	Fc receptor mediated inhibitory signaling pathway(GO:0002774)
5.8	121.1	GO:0031468	nuclear envelope reassembly(GO:0031468)
5.7	22.9	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
5.7	125.9	GO:0006825	copper ion transport(GO:0006825)
5.7	22.9	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
5.7	392.9	GO:0043488	regulation of mRNA stability(GO:0043488)
5.7	39.8	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
5.7	39.7	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
5.7	22.6	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
5.6	11.3	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
5.6	1580.8	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
5.6	123.1	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
5.6	72.4	GO:0050766	positive regulation of phagocytosis(GO:0050766)
5.5	16.6	GO:0016139	glycoside catabolic process(GO:0016139)
5.5	16.6	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
5.5	11.0	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
5.5	5.5	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
5.5	11.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
5.4	16.3	GO:0051684	maintenance of Golgi location(GO:0051684)
5.4	10.7	GO:0009886	post-embryonic morphogenesis(GO:0009886) post-embryonic organ morphogenesis(GO:0048563)
5.4	32.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
5.3	5.3	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
5.3	90.5	GO:0042340	keratan sulfate catabolic process(GO:0042340)
5.3	26.6	GO:0009303	rRNA transcription(GO:0009303)
5.3	16.0	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
5.3	15.9	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
5.3	52.8	GO:0034498	early endosome to Golgi transport(GO:0034498)
5.3	47.4	GO:0018344	protein geranylgeranylation(GO:0018344)
5.3	231.9	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
5.3	21.1	GO:0035879	plasma membrane lactate transport(GO:0035879)
5.3	31.6	GO:0042866	pyruvate biosynthetic process(GO:0042866)
5.3	15.8	GO:0043105	regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
5.2	47.2	GO:0018206	peptidyl-methionine modification(GO:0018206)
5.2	15.6	GO:0032497	detection of lipopolysaccharide(GO:0032497)
5.1	5.1	GO:1902566	regulation of eosinophil activation(GO:1902566)
5.1	154.0	GO:0007029	endoplasmic reticulum organization(GO:0007029)
5.1	35.8	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
5.0	5.0	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
5.0	5.0	GO:0002590	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
5.0	25.1	GO:1904424	regulation of GTP binding(GO:1904424)
5.0	25.0	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
5.0	9.9	GO:0015920	lipopolysaccharide transport(GO:0015920)
4.9	14.8	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
4.9	9.9	GO:0034214	protein hexamerization(GO:0034214)
4.9	9.8	GO:1903978	regulation of microglial cell activation(GO:1903978)
4.9	9.8	GO:0009147	pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
4.8	9.7	GO:0002353	kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
4.8	29.0	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
4.8	38.6	GO:0051382	kinetochore assembly(GO:0051382)
4.8	19.3	GO:0030920	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
4.8	230.9	GO:1990090	cellular response to nerve growth factor stimulus(GO:1990090)
4.8	14.4	GO:1902992	negative regulation of amyloid precursor protein catabolic process(GO:1902992)
4.8	19.2	GO:0061643	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
4.7	4.7	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
4.7	47.4	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
4.7	47.2	GO:1900086	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
4.7	18.9	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
4.7	56.2	GO:0007172	signal complex assembly(GO:0007172)
4.7	379.1	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
4.7	51.4	GO:0019388	galactose catabolic process(GO:0019388)
4.6	4.6	GO:0097113	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
4.6	9.2	GO:1902680	positive regulation of RNA biosynthetic process(GO:1902680)
4.6	9.2	GO:0044275	cellular carbohydrate catabolic process(GO:0044275)
4.6	41.2	GO:1903027	regulation of opsonization(GO:1903027)
4.6	45.6	GO:0045793	positive regulation of cell size(GO:0045793)
4.6	31.9	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
4.5	13.6	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
4.5	13.6	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
4.5	45.1	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
4.5	44.9	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
4.4	31.1	GO:0000733	DNA strand renaturation(GO:0000733)
4.4	13.3	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
4.4	30.9	GO:0051599	response to hydrostatic pressure(GO:0051599)
4.4	79.2	GO:0035641	locomotory exploration behavior(GO:0035641)
4.3	17.3	GO:1903224	regulation of endodermal cell differentiation(GO:1903224) negative regulation of gastrulation(GO:2000542)
4.3	25.9	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
4.3	30.2	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
4.3	8.6	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
4.3	25.8	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
4.3	68.4	GO:0007220	Notch receptor processing(GO:0007220)
4.3	8.5	GO:0002370	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
4.3	17.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
4.2	46.7	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
4.2	25.4	GO:0045357	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
4.2	42.3	GO:0060056	mammary gland involution(GO:0060056)
4.2	134.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
4.2	25.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
4.2	12.6	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
4.2	4.2	GO:0050917	sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
4.1	8.3	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
4.1	20.7	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
4.1	16.6	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
4.1	49.6	GO:0016578	histone deubiquitination(GO:0016578)
4.1	20.6	GO:1904693	midbrain morphogenesis(GO:1904693)
4.1	8.2	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
4.1	24.5	GO:0045064	T-helper 2 cell differentiation(GO:0045064)
4.1	8.2	GO:0061724	lipophagy(GO:0061724) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
4.1	24.4	GO:0043418	homocysteine catabolic process(GO:0043418)
4.1	32.6	GO:0070200	establishment of protein localization to telomere(GO:0070200)
4.1	8.1	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
4.1	4.1	GO:1990481	mRNA pseudouridine synthesis(GO:1990481)
4.1	48.7	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
4.1	20.3	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
4.0	16.2	GO:0036229	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
4.0	12.1	GO:0090155	negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
4.0	72.4	GO:0051290	protein heterotetramerization(GO:0051290)
4.0	28.1	GO:0008216	spermidine metabolic process(GO:0008216)
4.0	12.0	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
4.0	71.9	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
4.0	23.9	GO:0051974	negative regulation of telomerase activity(GO:0051974)
4.0	19.9	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
4.0	203.1	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
4.0	4.0	GO:0002351	serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
4.0	23.9	GO:0060011	Sertoli cell proliferation(GO:0060011)
4.0	39.7	GO:0071578	zinc II ion transmembrane import(GO:0071578)
4.0	7.9	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
3.9	15.8	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
3.9	98.3	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
3.9	15.7	GO:0039530	MDA-5 signaling pathway(GO:0039530)
3.9	11.8	GO:0090160	Golgi to lysosome transport(GO:0090160)
3.9	62.8	GO:0043304	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
3.9	7.8	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
3.9	23.5	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
3.9	7.8	GO:0008356	asymmetric cell division(GO:0008356)
3.9	27.2	GO:0031648	protein destabilization(GO:0031648)
3.9	34.9	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
3.9	19.4	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
3.9	19.3	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
3.8	53.7	GO:0035855	megakaryocyte development(GO:0035855)
3.8	194.9	GO:0038061	NIK/NF-kappaB signaling(GO:0038061)
3.8	3.8	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
3.8	117.7	GO:0090383	phagosome acidification(GO:0090383)
3.8	11.3	GO:0002418	immune response to tumor cell(GO:0002418)
3.8	56.6	GO:0031639	plasminogen activation(GO:0031639)
3.8	18.9	GO:1903232	melanosome assembly(GO:1903232)
3.8	41.5	GO:0002315	marginal zone B cell differentiation(GO:0002315)
3.8	11.3	GO:0030099	myeloid cell differentiation(GO:0030099)
3.8	60.1	GO:0098969	neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
3.7	63.4	GO:0000002	mitochondrial genome maintenance(GO:0000002)
3.7	14.9	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
3.7	7.4	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
3.7	26.0	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
3.7	37.1	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
3.7	7.4	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
3.7	18.5	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
3.7	25.8	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130)
3.7	158.2	GO:0043171	peptide catabolic process(GO:0043171)
3.7	25.7	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
3.7	58.6	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
3.7	11.0	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
3.7	25.6	GO:0032486	Rap protein signal transduction(GO:0032486)
3.6	90.7	GO:0009235	cobalamin metabolic process(GO:0009235)
3.6	18.0	GO:0000722	telomere maintenance via recombination(GO:0000722)
3.6	10.8	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
3.6	14.3	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
3.6	103.7	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
3.5	343.3	GO:0008380	RNA splicing(GO:0008380)
3.5	3.5	GO:0061034	olfactory bulb mitral cell layer development(GO:0061034)
3.5	28.0	GO:0001542	ovulation from ovarian follicle(GO:0001542)
3.5	17.5	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
3.5	55.6	GO:0006337	nucleosome disassembly(GO:0006337)
3.5	24.3	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
3.5	24.3	GO:0000012	single strand break repair(GO:0000012)
3.4	6.9	GO:0002384	hepatic immune response(GO:0002384)
3.4	10.3	GO:0035624	receptor transactivation(GO:0035624)
3.4	27.4	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
3.4	3.4	GO:0051595	response to methylglyoxal(GO:0051595)
3.4	6.8	GO:0044065	regulation of respiratory system process(GO:0044065)
3.4	95.4	GO:0007077	mitotic nuclear envelope disassembly(GO:0007077)
3.4	6.8	GO:0002347	response to tumor cell(GO:0002347)
3.4	27.1	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
3.4	10.1	GO:0002880	microglial cell activation involved in immune response(GO:0002282) chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880) negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
3.4	26.9	GO:0071404	cellular response to low-density lipoprotein particle stimulus(GO:0071404)
3.4	43.7	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
3.4	20.2	GO:0031935	regulation of chromatin silencing(GO:0031935)
3.4	70.4	GO:0006119	oxidative phosphorylation(GO:0006119)
3.4	23.5	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
3.3	26.7	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
3.3	9.9	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
3.3	16.5	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
3.3	32.7	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
3.3	13.1	GO:0060155	platelet dense granule organization(GO:0060155)
3.3	71.6	GO:0006903	vesicle targeting(GO:0006903)
3.2	6.5	GO:0043382	regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382)
3.2	155.3	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
3.2	19.4	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
3.2	9.7	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
3.2	3.2	GO:0010039	response to iron ion(GO:0010039)
3.2	6.4	GO:0090270	fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
3.2	69.6	GO:0043968	histone H2A acetylation(GO:0043968)
3.2	19.0	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
3.1	15.7	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
3.1	25.2	GO:1900223	positive regulation of beta-amyloid clearance(GO:1900223)
3.1	12.5	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
3.1	3.1	GO:0031291	Ran protein signal transduction(GO:0031291)
3.1	21.7	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
3.1	12.4	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
3.1	12.4	GO:0006183	GTP biosynthetic process(GO:0006183)
3.1	21.7	GO:0051561	positive regulation of mitochondrial calcium ion concentration(GO:0051561)
3.1	9.3	GO:0051661	maintenance of centrosome location(GO:0051661)
3.1	3.1	GO:0019346	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
3.1	6.2	GO:0021764	amygdala development(GO:0021764)
3.1	9.2	GO:0086054	pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
3.1	52.2	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
3.1	12.3	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
3.0	12.2	GO:0071352	interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352)
3.0	15.2	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
3.0	24.3	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
3.0	33.2	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
3.0	39.1	GO:0060632	regulation of microtubule-based movement(GO:0060632)
3.0	6.0	GO:0060434	bronchus morphogenesis(GO:0060434)
3.0	23.8	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
3.0	20.8	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
3.0	8.9	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
3.0	26.6	GO:0060576	intestinal epithelial cell development(GO:0060576)
2.9	8.8	GO:0090343	positive regulation of cell aging(GO:0090343)
2.9	8.8	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
2.9	2.9	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
2.9	14.6	GO:0007076	mitotic chromosome condensation(GO:0007076)
2.9	2.9	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
2.9	144.8	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
2.9	2.9	GO:0048709	oligodendrocyte differentiation(GO:0048709)
2.8	2.8	GO:0051182	coenzyme transport(GO:0051182)
2.8	8.5	GO:0046521	sphingoid catabolic process(GO:0046521)
2.8	22.5	GO:0035562	negative regulation of chromatin binding(GO:0035562)
2.8	14.0	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
2.8	5.6	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
2.8	39.0	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.8	22.3	GO:0015816	glycine transport(GO:0015816)
2.8	27.8	GO:0051016	barbed-end actin filament capping(GO:0051016)
2.8	5.5	GO:0016095	polyprenol catabolic process(GO:0016095)
2.8	16.5	GO:1903715	regulation of aerobic respiration(GO:1903715)
2.7	13.7	GO:1903599	positive regulation of mitophagy(GO:1903599)
2.7	5.5	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
2.7	16.4	GO:1902591	single-organism membrane budding(GO:1902591)
2.7	46.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
2.7	24.3	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
2.7	2.7	GO:0035627	ceramide transport(GO:0035627)
2.7	10.7	GO:0043555	regulation of translation in response to stress(GO:0043555)
2.7	5.3	GO:1901856	negative regulation of cellular respiration(GO:1901856)
2.6	7.8	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
2.6	15.6	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
2.6	10.3	GO:0015793	glycerol transport(GO:0015793)
2.6	25.6	GO:0006750	glutathione biosynthetic process(GO:0006750)
2.5	43.2	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
2.5	22.8	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
2.5	5.0	GO:0032639	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
2.5	17.6	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
2.5	25.0	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
2.5	39.9	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
2.5	37.1	GO:0008053	mitochondrial fusion(GO:0008053)
2.5	9.9	GO:0002934	desmosome organization(GO:0002934)
2.5	2.5	GO:0043985	histone H4-R3 methylation(GO:0043985)
2.5	12.3	GO:0001705	ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
2.4	36.7	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
2.4	24.4	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
2.4	16.9	GO:1902031	regulation of NADP metabolic process(GO:1902031)
2.4	12.0	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
2.4	19.1	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
2.4	2.4	GO:0051683	establishment of Golgi localization(GO:0051683)
2.4	9.5	GO:0034205	beta-amyloid formation(GO:0034205)
2.4	4.7	GO:0072757	cellular response to camptothecin(GO:0072757)
2.4	7.1	GO:0006642	triglyceride mobilization(GO:0006642)
2.4	9.5	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
2.4	26.0	GO:0032781	positive regulation of ATPase activity(GO:0032781)
2.4	21.2	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
2.3	4.7	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
2.3	35.2	GO:0032060	bleb assembly(GO:0032060)
2.3	4.7	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
2.3	9.3	GO:0071353	cellular response to interleukin-4(GO:0071353)
2.3	23.3	GO:0021815	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
2.3	9.3	GO:0071763	nuclear membrane organization(GO:0071763)
2.3	374.5	GO:0006457	protein folding(GO:0006457)
2.3	4.6	GO:0007266	Rho protein signal transduction(GO:0007266)
2.3	31.6	GO:0009313	oligosaccharide catabolic process(GO:0009313)
2.3	9.0	GO:0007613	memory(GO:0007613)
2.3	9.0	GO:0014894	response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
2.2	20.2	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
2.2	2.2	GO:2000618	regulation of histone H4-K16 acetylation(GO:2000618)
2.2	17.8	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
2.2	8.9	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
2.2	33.0	GO:0048853	forebrain morphogenesis(GO:0048853)
2.2	52.7	GO:0005980	glycogen catabolic process(GO:0005980)
2.2	4.4	GO:0060352	cell adhesion molecule production(GO:0060352)
2.2	6.5	GO:0032252	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252)
2.2	8.7	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
2.2	15.1	GO:0030091	protein repair(GO:0030091)
2.2	64.8	GO:0015721	bile acid and bile salt transport(GO:0015721)
2.2	21.5	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
2.1	10.7	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
2.1	10.7	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
2.1	6.4	GO:0010649	regulation of cell communication by electrical coupling(GO:0010649)
2.1	10.5	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
2.1	2.1	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
2.1	6.3	GO:0032581	ER-dependent peroxisome organization(GO:0032581)
2.1	12.5	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
2.1	24.7	GO:0016071	mRNA metabolic process(GO:0016071)
2.0	6.1	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
2.0	10.2	GO:0035247	peptidyl-arginine omega-N-methylation(GO:0035247)
2.0	40.4	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
2.0	2.0	GO:0048382	mesendoderm development(GO:0048382)
2.0	10.1	GO:1904274	tricellular tight junction assembly(GO:1904274)
2.0	2.0	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
2.0	30.0	GO:0007019	microtubule depolymerization(GO:0007019)
2.0	8.0	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
2.0	2.0	GO:0032647	regulation of interferon-alpha production(GO:0032647)
2.0	9.9	GO:0030263	apoptotic chromosome condensation(GO:0030263)
2.0	277.1	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043122)
2.0	11.8	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
2.0	19.5	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
2.0	50.8	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)
1.9	19.3	GO:0010452	histone H3-K36 methylation(GO:0010452)
1.9	13.5	GO:0006105	succinate metabolic process(GO:0006105)
1.9	55.2	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
1.9	15.2	GO:0007080	mitotic metaphase plate congression(GO:0007080)
1.9	13.2	GO:0051299	mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
1.9	30.1	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
1.9	5.6	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
1.9	41.1	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
1.9	7.4	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
1.9	3.7	GO:0051451	myoblast migration(GO:0051451)
1.9	9.3	GO:0006107	oxaloacetate metabolic process(GO:0006107)
1.9	14.8	GO:0033028	myeloid cell apoptotic process(GO:0033028)
1.8	51.7	GO:0006611	protein export from nucleus(GO:0006611)
1.8	5.5	GO:0090031	regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) positive regulation of steroid hormone biosynthetic process(GO:0090031)
1.8	3.6	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148) phosphatidylglycerol metabolic process(GO:0046471)
1.8	1.8	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
1.8	42.7	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.8	10.7	GO:0061038	uterus morphogenesis(GO:0061038)
1.8	24.8	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
1.8	39.0	GO:0017145	stem cell division(GO:0017145)
1.8	280.5	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
1.8	17.6	GO:1900034	regulation of cellular response to heat(GO:1900034)
1.7	1.7	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293) positive regulation of isotype switching to IgE isotypes(GO:0048295)
1.7	8.5	GO:0002335	mature B cell differentiation(GO:0002335)
1.7	8.5	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
1.7	28.4	GO:0032480	negative regulation of type I interferon production(GO:0032480)
1.7	20.0	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
1.7	5.0	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.7	5.0	GO:0061635	regulation of protein complex stability(GO:0061635)
1.7	3.3	GO:0001302	replicative cell aging(GO:0001302)
1.6	9.8	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.6	18.0	GO:0097186	amelogenesis(GO:0097186)
1.6	19.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
1.6	24.2	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
1.6	11.2	GO:0007379	segment specification(GO:0007379)
1.6	8.0	GO:0010624	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
1.6	11.1	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
1.6	23.8	GO:0044804	nucleophagy(GO:0044804)
1.6	15.9	GO:0003094	glomerular filtration(GO:0003094)
1.6	6.3	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
1.6	10.9	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.6	1.6	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
1.5	21.7	GO:0007265	Ras protein signal transduction(GO:0007265)
1.5	13.8	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
1.5	6.1	GO:0040016	embryonic cleavage(GO:0040016)
1.5	12.2	GO:0070995	NADPH oxidation(GO:0070995)
1.5	34.9	GO:0006270	DNA replication initiation(GO:0006270)
1.5	105.9	GO:0006635	fatty acid beta-oxidation(GO:0006635)
1.5	25.7	GO:1901880	negative regulation of protein depolymerization(GO:1901880)
1.5	108.8	GO:0050848	regulation of calcium-mediated signaling(GO:0050848)
1.5	23.9	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
1.5	8.9	GO:0033151	V(D)J recombination(GO:0033151)
1.5	11.9	GO:0039529	RIG-I signaling pathway(GO:0039529)
1.5	7.4	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
1.5	135.2	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
1.5	7.3	GO:0001880	Mullerian duct regression(GO:0001880)
1.5	5.9	GO:0046836	glycolipid transport(GO:0046836)
1.5	16.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
1.5	448.7	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
1.4	5.8	GO:1904059	regulation of locomotor rhythm(GO:1904059)
1.4	2.9	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
1.4	44.5	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
1.4	2.9	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.4	8.5	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
1.4	11.4	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.4	8.5	GO:0070162	adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
1.4	11.2	GO:0061718	NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.4	8.3	GO:0007018	microtubule-based movement(GO:0007018)
1.4	4.1	GO:0044344	cellular response to fibroblast growth factor stimulus(GO:0044344)
1.4	1.4	GO:0051030	snRNA export from nucleus(GO:0006408) snRNA transport(GO:0051030)
1.4	31.5	GO:0043966	histone H3 acetylation(GO:0043966)
1.4	1.4	GO:0010941	regulation of cell death(GO:0010941)
1.4	27.2	GO:0034508	centromere complex assembly(GO:0034508)
1.4	9.5	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.4	1.4	GO:1903201	regulation of oxidative stress-induced cell death(GO:1903201)
1.4	9.5	GO:2000785	regulation of autophagosome assembly(GO:2000785)
1.3	6.7	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
1.3	8.0	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
1.3	4.0	GO:0006591	ornithine metabolic process(GO:0006591)
1.3	30.6	GO:0006487	protein N-linked glycosylation(GO:0006487)
1.3	2.6	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
1.3	48.0	GO:0051289	protein homotetramerization(GO:0051289)
1.3	9.0	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
1.3	14.0	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566)
1.3	1.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
1.3	3.8	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
1.3	1.3	GO:0060462	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
1.2	11.2	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
1.2	3.7	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
1.2	57.9	GO:0006338	chromatin remodeling(GO:0006338)
1.2	2.4	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.2	7.2	GO:0048311	mitochondrion distribution(GO:0048311)
1.2	4.8	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286) positive regulation of caveolin-mediated endocytosis(GO:2001288)
1.2	11.9	GO:0007096	regulation of exit from mitosis(GO:0007096)
1.2	4.6	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
1.2	6.9	GO:0000212	meiotic spindle organization(GO:0000212)
1.2	5.8	GO:0097192	signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
1.2	1.2	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
1.1	1.1	GO:0032930	positive regulation of superoxide anion generation(GO:0032930)
1.1	2.2	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
1.1	11.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
1.1	2.2	GO:0031507	heterochromatin assembly(GO:0031507)
1.1	13.2	GO:2000179	positive regulation of neural precursor cell proliferation(GO:2000179)
1.1	4.4	GO:0033131	regulation of glucokinase activity(GO:0033131) negative regulation of glucokinase activity(GO:0033132) regulation of hexokinase activity(GO:1903299) negative regulation of hexokinase activity(GO:1903300)
1.1	2.2	GO:0006828	manganese ion transport(GO:0006828)
1.1	16.4	GO:0006622	protein targeting to lysosome(GO:0006622)
1.1	21.7	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
1.1	3.3	GO:0048701	embryonic cranial skeleton morphogenesis(GO:0048701)
1.1	31.4	GO:0031581	hemidesmosome assembly(GO:0031581)
1.1	1.1	GO:0010464	mesenchymal cell proliferation(GO:0010463) regulation of mesenchymal cell proliferation(GO:0010464)
1.1	4.3	GO:0003409	optic cup structural organization(GO:0003409)
1.1	3.2	GO:0097264	self proteolysis(GO:0097264)
1.1	2.1	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
1.1	1.1	GO:0016191	synaptic vesicle uncoating(GO:0016191) vesicle uncoating(GO:0072319)
1.0	2.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
1.0	6.1	GO:0032897	negative regulation of viral transcription(GO:0032897)
1.0	11.2	GO:0050684	regulation of mRNA processing(GO:0050684)
1.0	1.0	GO:0042993	positive regulation of transcription factor import into nucleus(GO:0042993)
1.0	3.9	GO:0009144	purine nucleoside triphosphate metabolic process(GO:0009144)
1.0	13.8	GO:0035065	regulation of histone acetylation(GO:0035065)
1.0	5.9	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
1.0	2.0	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
1.0	114.5	GO:0008360	regulation of cell shape(GO:0008360)
1.0	75.9	GO:0034728	nucleosome organization(GO:0034728)
1.0	5.8	GO:0035897	proteolysis in other organism(GO:0035897)
1.0	3.9	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
1.0	2.9	GO:0051712	positive regulation of killing of cells of other organism(GO:0051712)
1.0	65.5	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.9	28.3	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.9	36.7	GO:0071277	cellular response to calcium ion(GO:0071277)
0.9	9.4	GO:0006378	mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.9	2.8	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.9	3.6	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.9	2.7	GO:0003341	cilium movement(GO:0003341)
0.9	9.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.9	15.2	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.9	1.8	GO:0060242	contact inhibition(GO:0060242)
0.9	2.6	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.9	8.8	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.9	2.6	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.9	8.5	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.9	1.7	GO:0035995	detection of muscle stretch(GO:0035995)
0.8	4.2	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.8	6.6	GO:0018065	protein-cofactor linkage(GO:0018065)
0.8	3.3	GO:0030728	ovulation(GO:0030728)
0.8	1.6	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.8	1.6	GO:0048477	oogenesis(GO:0048477)
0.8	1.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.8	4.8	GO:0038092	nodal signaling pathway(GO:0038092)
0.8	0.8	GO:0097205	renal filtration(GO:0097205)
0.8	8.7	GO:0017085	response to insecticide(GO:0017085)
0.8	18.9	GO:0015893	drug transport(GO:0015893)
0.8	3.1	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075) endochondral bone morphogenesis(GO:0060350)
0.8	4.6	GO:0042100	B cell proliferation(GO:0042100)
0.8	3.1	GO:0060017	parathyroid gland development(GO:0060017)
0.8	17.4	GO:1903578	regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.7	5.1	GO:0009650	UV protection(GO:0009650)
0.7	2.9	GO:0035411	catenin import into nucleus(GO:0035411)
0.7	2.1	GO:1903054	negative regulation of extracellular matrix assembly(GO:1901202) negative regulation of extracellular matrix organization(GO:1903054)
0.7	2.1	GO:0046958	nonassociative learning(GO:0046958)
0.7	0.7	GO:0009635	response to herbicide(GO:0009635)
0.7	2.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.7	2.8	GO:0048014	Tie signaling pathway(GO:0048014) negative regulation of positive chemotaxis(GO:0050928)
0.7	0.7	GO:0014065	phosphatidylinositol 3-kinase signaling(GO:0014065)
0.7	9.4	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.7	3.3	GO:0032418	lysosome localization(GO:0032418)
0.7	5.3	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.7	3.3	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.7	6.6	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.7	2.6	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.6	4.5	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.6	1.9	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.6	14.6	GO:0006582	melanin metabolic process(GO:0006582)
0.6	1.2	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.6	3.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.6	5.5	GO:0033227	dsRNA transport(GO:0033227)
0.6	11.6	GO:0006099	tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101)
0.6	3.0	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.6	1.2	GO:0002577	regulation of antigen processing and presentation(GO:0002577)
0.6	0.6	GO:0034138	toll-like receptor 3 signaling pathway(GO:0034138)
0.6	1.2	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
0.6	5.8	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.6	2.9	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.6	2.9	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.6	1.1	GO:0031268	pseudopodium organization(GO:0031268)
0.6	3.4	GO:0001676	long-chain fatty acid metabolic process(GO:0001676)
0.6	3.9	GO:0090630	activation of GTPase activity(GO:0090630)
0.6	1.7	GO:0042418	epinephrine biosynthetic process(GO:0042418)
0.5	1.1	GO:0003289	septum secundum development(GO:0003285) atrial septum primum morphogenesis(GO:0003289) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.5	0.5	GO:0002644	negative regulation of tolerance induction(GO:0002644)
0.5	5.4	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.5	1.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.5	1.1	GO:0090344	negative regulation of cell aging(GO:0090344)
0.5	5.3	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.5	3.7	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.5	2.6	GO:0046785	microtubule polymerization(GO:0046785)
0.5	2.6	GO:0090032	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of hormone biosynthetic process(GO:0032353) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.5	1.5	GO:0032310	prostaglandin secretion(GO:0032310)
0.5	7.6	GO:0048268	clathrin coat assembly(GO:0048268)
0.5	8.0	GO:0051865	protein autoubiquitination(GO:0051865)
0.5	4.1	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.5	31.4	GO:0002576	platelet degranulation(GO:0002576)
0.5	5.0	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.4	4.5	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.4	3.1	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.4	12.7	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.4	7.4	GO:0006308	DNA catabolic process(GO:0006308)
0.4	2.2	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.4	1.7	GO:0072350	tricarboxylic acid metabolic process(GO:0072350)
0.4	13.7	GO:0007030	Golgi organization(GO:0007030)
0.4	0.9	GO:0071109	superior temporal gyrus development(GO:0071109)
0.4	1.3	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.4	0.4	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.4	1.7	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.4	0.4	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.4	0.8	GO:0006549	isoleucine metabolic process(GO:0006549) isoleucine catabolic process(GO:0006550)
0.4	1.6	GO:0034334	adherens junction maintenance(GO:0034334)
0.4	1.2	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4	0.8	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.4	2.2	GO:0070875	positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.4	1.8	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.4	0.4	GO:1900133	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.4	1.1	GO:0010455	positive regulation of cell fate commitment(GO:0010455)
0.4	1.4	GO:0061146	mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146)
0.4	1.1	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.3	0.7	GO:0043038	amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.3	0.7	GO:0015791	polyol transport(GO:0015791)
0.3	2.9	GO:0016925	protein sumoylation(GO:0016925)
0.3	1.3	GO:0051283	sequestering of calcium ion(GO:0051208) release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.3	4.0	GO:0030865	cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.3	2.1	GO:0051026	chiasma assembly(GO:0051026)
0.3	0.3	GO:0002251	organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.3	0.6	GO:0035994	response to muscle stretch(GO:0035994)
0.3	2.0	GO:1903206	negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.3	0.3	GO:0014823	response to activity(GO:0014823)
0.3	2.0	GO:0061430	bone trabecula morphogenesis(GO:0061430)
0.3	3.9	GO:0006068	ethanol catabolic process(GO:0006068)
0.3	0.5	GO:0061289	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3	4.7	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.2	0.7	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.2	6.7	GO:0031100	organ regeneration(GO:0031100)
0.2	1.0	GO:0042940	D-amino acid transport(GO:0042940)
0.2	2.2	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.2	0.2	GO:0046683	response to organophosphorus(GO:0046683)
0.2	0.7	GO:0033194	response to hydroperoxide(GO:0033194)
0.2	0.9	GO:1903901	negative regulation of viral life cycle(GO:1903901)
0.2	0.9	GO:0048706	embryonic skeletal system development(GO:0048706)
0.2	1.8	GO:0035306	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.2	0.6	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.2	1.5	GO:0046697	decidualization(GO:0046697)
0.2	0.6	GO:0021564	vagus nerve development(GO:0021564)
0.2	8.9	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2	2.0	GO:0019079	viral genome replication(GO:0019079)
0.2	0.2	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.2	0.2	GO:0090382	phagosome maturation(GO:0090382)
0.2	0.9	GO:1902946	protein localization to early endosome(GO:1902946)
0.2	1.3	GO:1901186	positive regulation of ERBB signaling pathway(GO:1901186)
0.2	0.4	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.2	0.5	GO:0007512	adult heart development(GO:0007512)
0.2	3.3	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.2	0.5	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.2	1.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.2	0.7	GO:0009082	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2	2.3	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.2	0.7	GO:1903831	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2	2.9	GO:0019731	antibacterial humoral response(GO:0019731)
0.1	0.8	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.1	0.1	GO:0071609	chemokine (C-C motif) ligand 5 production(GO:0071609)
0.1	0.4	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.5	GO:0006705	mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1	1.2	GO:0006833	water transport(GO:0006833)
0.1	0.7	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	0.2	GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.1	0.9	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	0.9	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	0.7	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1	0.8	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	0.4	GO:0030299	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1	0.9	GO:0048246	macrophage chemotaxis(GO:0048246)
0.1	0.6	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.1	1.7	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.1	0.5	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.1	0.4	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1	1.0	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.1	1.2	GO:0007520	myoblast fusion(GO:0007520)
0.1	0.6	GO:0010608	posttranscriptional regulation of gene expression(GO:0010608)
0.1	0.4	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.1	0.2	GO:0070932	histone H3 deacetylation(GO:0070932)
0.1	0.2	GO:0046137	negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.3	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.1	1.0	GO:0001541	ovarian follicle development(GO:0001541)
0.1	0.2	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.1	0.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.3	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1	0.5	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
0.0	0.1	GO:0042182	ketone catabolic process(GO:0042182)
0.0	0.4	GO:0002076	osteoblast development(GO:0002076)
0.0	0.5	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.0	0.3	GO:0016048	detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.0	0.2	GO:0001701	in utero embryonic development(GO:0001701)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
129.7	389.1	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
87.2	784.6	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
76.3	610.8	GO:0034715	pICln-Sm protein complex(GO:0034715)
64.9	649.4	GO:0034709	methylosome(GO:0034709)
58.0	696.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
57.0	455.6	GO:1990111	spermatoproteasome complex(GO:1990111)
51.0	306.2	GO:1902560	GMP reductase complex(GO:1902560)
48.3	193.0	GO:0070985	TFIIK complex(GO:0070985)
46.6	279.5	GO:0071817	MMXD complex(GO:0071817)
46.5	186.2	GO:0071001	U4/U6 snRNP(GO:0071001)
46.0	230.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
44.9	224.6	GO:0042643	actomyosin, actin portion(GO:0042643)
40.9	122.6	GO:0071159	NF-kappaB complex(GO:0071159)
39.5	118.4	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
38.8	465.2	GO:0031595	nuclear proteasome complex(GO:0031595)
38.7	116.0	GO:0018444	translation release factor complex(GO:0018444)
38.5	269.3	GO:0005787	signal peptidase complex(GO:0005787)
38.2	152.7	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
38.1	304.7	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
37.1	111.4	GO:0030289	protein phosphatase 4 complex(GO:0030289)
36.6	219.4	GO:0005688	U6 snRNP(GO:0005688)
35.9	35.9	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
35.4	35.4	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
34.4	171.8	GO:0071986	Ragulator complex(GO:0071986)
34.0	170.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
33.8	101.4	GO:0034455	t-UTP complex(GO:0034455)
33.7	674.5	GO:0005838	proteasome regulatory particle(GO:0005838)
33.3	233.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
33.1	298.2	GO:0072546	ER membrane protein complex(GO:0072546)
32.2	610.9	GO:0005885	Arp2/3 protein complex(GO:0005885)
30.8	215.9	GO:0000172	ribonuclease MRP complex(GO:0000172)
29.5	177.2	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
28.8	288.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
27.7	857.7	GO:0030687	preribosome, large subunit precursor(GO:0030687)
27.2	81.6	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
27.1	324.7	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
27.0	405.7	GO:0005686	U2 snRNP(GO:0005686)
26.6	133.1	GO:0098837	postsynaptic recycling endosome(GO:0098837)
25.8	129.2	GO:0032021	NELF complex(GO:0032021)
25.8	541.8	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
25.8	128.9	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
25.6	102.6	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
25.3	151.8	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
24.9	323.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
24.6	73.8	GO:0031372	UBC13-MMS2 complex(GO:0031372)
24.2	72.5	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
24.0	72.0	GO:0097441	basilar dendrite(GO:0097441)
24.0	24.0	GO:0005687	U4 snRNP(GO:0005687)
23.6	236.5	GO:0000796	condensin complex(GO:0000796)
23.3	163.4	GO:0005663	DNA replication factor C complex(GO:0005663)
23.0	69.1	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
23.0	368.1	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
22.8	113.8	GO:0071797	LUBAC complex(GO:0071797)
22.4	111.9	GO:0097149	centralspindlin complex(GO:0097149)
22.0	65.9	GO:0035370	UBC13-UEV1A complex(GO:0035370)
21.9	87.7	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
21.5	150.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
21.4	64.1	GO:0005674	transcription factor TFIIF complex(GO:0005674)
21.3	127.8	GO:0008537	proteasome activator complex(GO:0008537)
21.1	190.3	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
20.7	145.0	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
20.3	81.4	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
20.1	240.7	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
19.2	307.6	GO:0031080	nuclear pore outer ring(GO:0031080)
18.8	188.1	GO:0097255	R2TP complex(GO:0097255)
18.4	92.2	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
18.3	238.0	GO:0042555	MCM complex(GO:0042555)
18.3	54.8	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
17.9	107.5	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
17.9	393.9	GO:0030127	COPII vesicle coat(GO:0030127)
17.2	310.4	GO:0097342	ripoptosome(GO:0097342)
17.1	51.4	GO:0030688	preribosome, small subunit precursor(GO:0030688)
17.1	153.6	GO:0000439	core TFIIH complex(GO:0000439)
17.0	119.1	GO:0016272	prefoldin complex(GO:0016272)
16.9	1813.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
16.8	151.2	GO:0030126	COPI vesicle coat(GO:0030126)
16.6	298.9	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
16.6	215.3	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
16.0	160.4	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
15.9	63.7	GO:0005846	nuclear cap binding complex(GO:0005846)
15.9	79.5	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
15.8	31.6	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
15.7	266.9	GO:0030686	90S preribosome(GO:0030686)
15.5	293.8	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
15.4	230.9	GO:0030684	preribosome(GO:0030684)
15.3	183.9	GO:0030008	TRAPP complex(GO:0030008)
15.2	76.2	GO:0043564	Ku70:Ku80 complex(GO:0043564)
15.0	119.9	GO:0032133	chromosome passenger complex(GO:0032133)
14.8	74.2	GO:0033503	HULC complex(GO:0033503)
14.6	131.0	GO:0033588	Elongator holoenzyme complex(GO:0033588)
14.3	42.8	GO:1902636	kinociliary basal body(GO:1902636)
14.2	56.7	GO:0044611	nuclear pore inner ring(GO:0044611)
14.1	42.4	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
14.1	56.5	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
14.0	126.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
14.0	181.9	GO:0005662	DNA replication factor A complex(GO:0005662)
13.8	13.8	GO:0000811	GINS complex(GO:0000811)
13.8	41.4	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
13.7	95.7	GO:0002178	palmitoyltransferase complex(GO:0002178)
13.7	95.7	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
13.6	176.7	GO:0000815	ESCRT III complex(GO:0000815)
13.6	54.3	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
13.6	257.7	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
13.6	94.9	GO:0070531	BRCA1-A complex(GO:0070531)
13.2	52.9	GO:0070876	SOSS complex(GO:0070876)
13.2	356.6	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
13.1	144.1	GO:0036452	ESCRT complex(GO:0036452)
13.1	182.9	GO:0090543	Flemming body(GO:0090543)
13.1	65.3	GO:0009368	endopeptidase Clp complex(GO:0009368)
13.0	519.7	GO:0015934	large ribosomal subunit(GO:0015934)
12.9	142.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
12.9	90.0	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
12.8	89.8	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
12.8	128.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
12.7	229.2	GO:0005685	U1 snRNP(GO:0005685)
12.5	375.6	GO:0005680	anaphase-promoting complex(GO:0005680)
12.5	87.4	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
12.4	224.0	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
12.3	49.4	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
12.3	147.9	GO:0097433	dense body(GO:0097433)
12.3	85.9	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
12.2	48.9	GO:0031510	SUMO activating enzyme complex(GO:0031510)
12.2	232.1	GO:0036020	endolysosome membrane(GO:0036020)
12.2	122.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
12.0	84.2	GO:0031298	replication fork protection complex(GO:0031298)
11.9	785.9	GO:0015935	small ribosomal subunit(GO:0015935)
11.9	83.3	GO:0035861	site of double-strand break(GO:0035861)
11.8	129.4	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
11.7	82.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
11.7	70.3	GO:0070435	Shc-EGFR complex(GO:0070435)
11.7	128.8	GO:0030125	clathrin vesicle coat(GO:0030125)
11.6	92.9	GO:0042382	paraspeckles(GO:0042382)
11.6	34.8	GO:0031262	Ndc80 complex(GO:0031262)
11.5	80.3	GO:0005956	protein kinase CK2 complex(GO:0005956)
11.4	34.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
11.4	136.6	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
11.3	45.3	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
11.2	44.8	GO:0032044	DSIF complex(GO:0032044)
11.2	122.7	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
11.0	143.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
11.0	11.0	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
11.0	87.7	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
10.8	21.6	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
10.8	75.5	GO:0030870	Mre11 complex(GO:0030870)
10.8	21.5	GO:0005905	clathrin-coated pit(GO:0005905)
10.7	53.7	GO:0032449	CBM complex(GO:0032449)
10.6	42.5	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
10.4	10.4	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
10.3	61.9	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
10.3	144.1	GO:0001673	male germ cell nucleus(GO:0001673)
10.3	143.6	GO:0044613	nuclear pore central transport channel(GO:0044613)
10.2	20.5	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
10.2	61.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
10.2	50.9	GO:0035061	interchromatin granule(GO:0035061)
10.1	20.2	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
10.0	110.4	GO:0070765	gamma-secretase complex(GO:0070765)
10.0	897.8	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
9.8	39.3	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
9.7	300.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
9.5	408.6	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
9.5	483.0	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
9.5	85.2	GO:0005814	centriole(GO:0005814)
9.5	151.3	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
9.3	27.8	GO:0031523	Myb complex(GO:0031523)
9.1	73.0	GO:0032039	integrator complex(GO:0032039)
9.0	44.9	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
8.9	26.8	GO:0005839	proteasome core complex(GO:0005839)
8.9	62.3	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
8.9	88.9	GO:0001739	sex chromatin(GO:0001739)
8.9	35.5	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
8.9	894.8	GO:0035578	azurophil granule lumen(GO:0035578)
8.8	35.0	GO:0032301	MutSalpha complex(GO:0032301)
8.5	518.0	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
8.5	76.1	GO:0044194	cytolytic granule(GO:0044194)
8.4	58.6	GO:0061617	MICOS complex(GO:0061617)
8.3	91.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
8.1	32.5	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
8.1	16.2	GO:0044615	nuclear pore nuclear basket(GO:0044615)
8.1	32.3	GO:0045273	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
8.0	31.8	GO:1990730	VCP-NSFL1C complex(GO:1990730)
8.0	620.1	GO:0005681	spliceosomal complex(GO:0005681)
7.8	62.8	GO:0000322	storage vacuole(GO:0000322)
7.8	7.8	GO:0020003	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
7.8	101.5	GO:0097136	Bcl-2 family protein complex(GO:0097136)
7.8	23.3	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
7.7	139.4	GO:0001891	phagocytic cup(GO:0001891)
7.7	23.1	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
7.7	69.1	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
7.5	37.4	GO:1990425	ryanodine receptor complex(GO:1990425)
7.4	52.0	GO:0071203	WASH complex(GO:0071203)
7.4	73.9	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
7.2	43.5	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
7.1	28.5	GO:0043625	delta DNA polymerase complex(GO:0043625)
7.1	128.2	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
7.1	540.0	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
7.1	77.6	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
7.1	49.4	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
7.0	28.0	GO:0070822	Sin3-type complex(GO:0070822)
7.0	195.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
6.8	440.5	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
6.6	33.1	GO:0030905	retromer, tubulation complex(GO:0030905)
6.6	13.2	GO:0042627	chylomicron(GO:0042627)
6.6	79.4	GO:0017119	Golgi transport complex(GO:0017119)
6.4	12.9	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
6.4	19.3	GO:0070939	Dsl1p complex(GO:0070939)
6.4	6.4	GO:1904724	tertiary granule lumen(GO:1904724)
6.3	38.0	GO:0032010	phagolysosome(GO:0032010)
6.3	897.1	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
6.3	213.1	GO:0090544	BAF-type complex(GO:0090544)
6.1	18.2	GO:1990393	3M complex(GO:1990393)
6.1	48.5	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
6.0	24.2	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
6.0	402.7	GO:0005643	nuclear pore(GO:0005643)
5.9	17.8	GO:1990423	RZZ complex(GO:1990423)
5.9	275.3	GO:0001772	immunological synapse(GO:0001772)
5.8	11.6	GO:0055087	Ski complex(GO:0055087)
5.8	17.3	GO:0005588	collagen type V trimer(GO:0005588)
5.7	120.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
5.7	244.0	GO:0005840	ribosome(GO:0005840)
5.7	73.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
5.6	61.3	GO:0032585	multivesicular body membrane(GO:0032585)
5.5	22.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
5.5	33.0	GO:0032009	early phagosome(GO:0032009)
5.3	47.5	GO:0016600	flotillin complex(GO:0016600)
5.2	5.2	GO:1990462	omegasome(GO:1990462)
5.2	25.9	GO:0001741	XY body(GO:0001741)
5.0	39.7	GO:0030670	phagocytic vesicle membrane(GO:0030670)
5.0	624.2	GO:0005795	Golgi stack(GO:0005795)
5.0	44.6	GO:0097550	transcriptional preinitiation complex(GO:0097550)
4.9	44.1	GO:0097413	Lewy body(GO:0097413)
4.7	9.5	GO:0045259	proton-transporting ATP synthase complex(GO:0045259)
4.7	74.6	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
4.6	13.9	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
4.6	4.6	GO:0044308	axonal spine(GO:0044308)
4.6	13.9	GO:0000798	nuclear cohesin complex(GO:0000798)
4.6	55.4	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
4.6	13.8	GO:0031415	NatA complex(GO:0031415)
4.5	17.8	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
4.4	52.9	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
4.4	8.8	GO:0005726	perichromatin fibrils(GO:0005726)
4.4	22.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
4.4	21.8	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
4.3	291.1	GO:0005758	mitochondrial intermembrane space(GO:0005758)
4.3	30.2	GO:0031264	death-inducing signaling complex(GO:0031264)
4.3	17.0	GO:1990031	pinceau fiber(GO:1990031)
4.2	12.7	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
4.2	21.2	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
4.2	92.9	GO:0098553	integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
4.2	8.4	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
4.2	235.1	GO:0005871	kinesin complex(GO:0005871)
4.2	120.9	GO:0016469	proton-transporting two-sector ATPase complex(GO:0016469)
4.1	41.3	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
4.1	8.2	GO:0005826	actomyosin contractile ring(GO:0005826)
4.1	32.5	GO:0045335	phagocytic vesicle(GO:0045335)
4.0	20.2	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
4.0	20.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
4.0	51.9	GO:0031209	SCAR complex(GO:0031209)
3.9	321.9	GO:0017053	transcriptional repressor complex(GO:0017053)
3.8	18.9	GO:0071439	clathrin complex(GO:0071439)
3.8	3.8	GO:0048188	Set1C/COMPASS complex(GO:0048188)
3.7	326.2	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
3.7	232.2	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
3.7	115.3	GO:0030173	integral component of Golgi membrane(GO:0030173)
3.7	84.5	GO:0000930	gamma-tubulin complex(GO:0000930)
3.6	14.5	GO:0005965	protein farnesyltransferase complex(GO:0005965)
3.6	378.0	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
3.6	25.2	GO:0070652	HAUS complex(GO:0070652)
3.5	17.6	GO:0044754	autolysosome(GO:0044754)
3.5	125.7	GO:0008180	COP9 signalosome(GO:0008180)
3.5	250.6	GO:0070821	tertiary granule membrane(GO:0070821)
3.5	6.9	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
3.5	3.5	GO:0000346	transcription export complex(GO:0000346)
3.4	20.7	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
3.4	27.5	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
3.4	20.4	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
3.4	10.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
3.3	23.3	GO:0072487	MSL complex(GO:0072487)
3.3	92.0	GO:0031258	lamellipodium membrane(GO:0031258)
3.3	6.5	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
3.2	6.5	GO:0002079	inner acrosomal membrane(GO:0002079)
3.2	19.4	GO:0005869	dynactin complex(GO:0005869)
3.2	1057.6	GO:0016607	nuclear speck(GO:0016607)
3.2	1223.5	GO:0005635	nuclear envelope(GO:0005635)
3.1	15.6	GO:0016589	NURF complex(GO:0016589)
3.1	12.5	GO:0031010	ISWI-type complex(GO:0031010)
3.0	15.2	GO:0043203	axon hillock(GO:0043203)
3.0	12.1	GO:0030891	VCB complex(GO:0030891)
2.9	11.8	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
2.9	126.3	GO:0035579	specific granule membrane(GO:0035579)
2.9	29.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
2.9	8.7	GO:0001652	granular component(GO:0001652)
2.9	11.5	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
2.9	5.7	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
2.8	39.7	GO:0031105	septin complex(GO:0031105)
2.8	5.7	GO:0051233	spindle midzone(GO:0051233)
2.8	39.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
2.8	55.9	GO:0005876	spindle microtubule(GO:0005876)
2.8	72.0	GO:0099738	cell cortex region(GO:0099738)
2.7	8.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
2.7	57.3	GO:0000502	proteasome complex(GO:0000502)
2.7	171.0	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
2.7	8.1	GO:0071748	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
2.7	239.0	GO:0016605	PML body(GO:0016605)
2.7	642.4	GO:0019866	organelle inner membrane(GO:0019866)
2.7	10.6	GO:0019815	B cell receptor complex(GO:0019815)
2.6	7.9	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
2.6	36.6	GO:0031932	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
2.6	5.2	GO:1905202	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
2.5	28.0	GO:0044216	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
2.4	60.8	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
2.3	21.1	GO:0034464	BBSome(GO:0034464)
2.3	39.5	GO:0002102	podosome(GO:0002102)
2.2	19.9	GO:0042588	zymogen granule(GO:0042588)
2.2	6.6	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
2.2	84.4	GO:0045095	keratin filament(GO:0045095)
2.1	8.3	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
2.1	4.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
2.0	51.1	GO:0070461	SAGA-type complex(GO:0070461)
1.9	250.2	GO:0031968	organelle outer membrane(GO:0031968)
1.9	11.5	GO:0097539	ciliary transition fiber(GO:0097539)
1.9	16.9	GO:0030904	retromer complex(GO:0030904)
1.9	48.7	GO:0045171	intercellular bridge(GO:0045171)
1.9	1.9	GO:0097542	ciliary tip(GO:0097542)
1.9	5.6	GO:0000803	sex chromosome(GO:0000803)
1.8	31.4	GO:0005719	nuclear euchromatin(GO:0005719)
1.8	5.5	GO:0005801	cis-Golgi network(GO:0005801)
1.8	14.6	GO:0005610	laminin-5 complex(GO:0005610)
1.8	10.7	GO:0032311	angiogenin-PRI complex(GO:0032311)
1.7	6.9	GO:0005896	interleukin-6 receptor complex(GO:0005896)
1.7	1.7	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
1.7	10.1	GO:0061689	tricellular tight junction(GO:0061689)
1.7	58.5	GO:0019814	immunoglobulin complex(GO:0019814)
1.7	5.0	GO:0031088	platelet dense granule membrane(GO:0031088)
1.7	6.6	GO:0070187	telosome(GO:0070187)
1.6	4.9	GO:0070578	RISC-loading complex(GO:0070578)
1.6	14.8	GO:0005964	phosphorylase kinase complex(GO:0005964)
1.6	316.9	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.6	1.6	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
1.6	16.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
1.6	3.2	GO:0070938	contractile ring(GO:0070938)
1.6	25.2	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
1.5	3679.6	GO:0070062	extracellular exosome(GO:0070062)
1.4	21.1	GO:0035580	specific granule lumen(GO:0035580)
1.4	4.2	GO:0031201	SNARE complex(GO:0031201)
1.4	108.8	GO:0005819	spindle(GO:0005819)
1.4	1.4	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
1.4	24.6	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
1.4	5.4	GO:0045178	basal part of cell(GO:0045178)
1.3	5.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
1.2	6.2	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
1.2	2.5	GO:0032389	MutLalpha complex(GO:0032389)
1.2	44.1	GO:0043198	dendritic shaft(GO:0043198)
1.2	5.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
1.2	13.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
1.2	3.5	GO:0032279	asymmetric synapse(GO:0032279)
1.1	3.4	GO:0031528	microvillus membrane(GO:0031528)
1.1	12.1	GO:0005844	polysome(GO:0005844)
1.1	7.6	GO:0015629	actin cytoskeleton(GO:0015629)
1.1	40.8	GO:0000777	condensed chromosome kinetochore(GO:0000777)
1.1	12.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
1.1	6.3	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
1.0	21.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
1.0	9.0	GO:0042101	T cell receptor complex(GO:0042101)
1.0	18.7	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.9	6.6	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.9	13.1	GO:0097346	INO80-type complex(GO:0097346)
0.9	2.8	GO:0034676	integrin alpha6-beta4 complex(GO:0034676)
0.9	41.8	GO:0030175	filopodium(GO:0030175)
0.9	58.1	GO:0000922	spindle pole(GO:0000922)
0.8	2.4	GO:0005960	glycine cleavage complex(GO:0005960)
0.8	13.5	GO:0000118	histone deacetylase complex(GO:0000118)
0.8	10.9	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.8	35.7	GO:0005903	brush border(GO:0005903)
0.8	3.8	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.8	18.1	GO:0005901	caveola(GO:0005901)
0.7	7.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.7	11.1	GO:0005657	replication fork(GO:0005657)
0.6	1.3	GO:0042827	platelet dense granule(GO:0042827)
0.6	1.8	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.6	7.1	GO:0031430	M band(GO:0031430)
0.6	2.3	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.6	9.0	GO:0031902	late endosome membrane(GO:0031902)
0.6	5.0	GO:0005605	basal lamina(GO:0005605)
0.5	5.9	GO:0000145	exocyst(GO:0000145)
0.4	1.7	GO:0071141	SMAD protein complex(GO:0071141)
0.4	2.9	GO:0097228	sperm principal piece(GO:0097228)
0.4	1.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.4	0.8	GO:0042584	chromaffin granule membrane(GO:0042584)
0.3	1.7	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3	1.4	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2	27.0	GO:0009897	external side of plasma membrane(GO:0009897)
0.2	3.3	GO:0032982	myosin filament(GO:0032982)
0.2	7.2	GO:0016363	nuclear matrix(GO:0016363)
0.2	0.9	GO:0097443	sorting endosome(GO:0097443)
0.1	1.5	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.4	GO:0033150	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.1	1.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.2	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.7	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	4.3	GO:0031966	mitochondrial membrane(GO:0031966)
0.1	62.0	GO:0005739	mitochondrion(GO:0005739)
0.1	0.4	GO:0044292	dendrite terminus(GO:0044292)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
129.7	389.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
76.8	383.8	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
64.8	194.5	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
56.8	113.6	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
56.5	338.7	GO:0030621	U4 snRNA binding(GO:0030621)
55.8	167.3	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
53.8	161.3	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
52.6	526.5	GO:0070990	snRNP binding(GO:0070990)
51.3	153.8	GO:0004492	methylmalonyl-CoA decarboxylase activity(GO:0004492)
51.0	306.2	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
48.3	96.5	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
48.3	144.8	GO:0042134	rRNA primary transcript binding(GO:0042134)
46.3	185.1	GO:0032217	riboflavin transporter activity(GO:0032217)
43.8	1313.2	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
38.2	420.5	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
38.1	114.3	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
38.0	190.2	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
37.7	113.2	GO:0036317	tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
37.1	111.4	GO:0034511	U3 snoRNA binding(GO:0034511)
36.7	183.5	GO:0043023	ribosomal large subunit binding(GO:0043023)
36.5	109.5	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
35.4	283.4	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
35.1	105.2	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
34.2	102.5	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
33.9	304.7	GO:0008312	7S RNA binding(GO:0008312)
33.7	134.9	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
33.7	269.6	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
33.4	133.5	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
33.0	198.1	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
32.7	327.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
31.8	190.8	GO:0005346	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
31.5	189.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
30.6	275.5	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
30.3	30.3	GO:0048256	flap endonuclease activity(GO:0048256)
29.6	326.1	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
29.6	118.4	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
29.5	88.4	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
29.4	88.1	GO:0001069	regulatory region RNA binding(GO:0001069)
28.9	231.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
28.8	633.4	GO:0000339	RNA cap binding(GO:0000339)
28.7	200.6	GO:0030620	U2 snRNA binding(GO:0030620)
27.8	111.3	GO:0002060	purine nucleobase binding(GO:0002060)
27.7	83.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
27.2	81.6	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
26.8	26.8	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
26.1	78.4	GO:0017130	poly(C) RNA binding(GO:0017130)
26.0	26.0	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
25.8	129.0	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
25.3	151.8	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
24.9	174.6	GO:0061133	endopeptidase activator activity(GO:0061133)
23.7	94.9	GO:0005046	KDEL sequence binding(GO:0005046)
23.0	183.7	GO:0000405	bubble DNA binding(GO:0000405)
22.8	159.4	GO:0047134	protein-disulfide reductase activity(GO:0047134)
22.3	490.5	GO:0042609	CD4 receptor binding(GO:0042609)
22.0	66.1	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
21.9	21.9	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
21.8	130.5	GO:0042296	ISG15 transferase activity(GO:0042296)
21.5	64.5	GO:0017108	5'-flap endonuclease activity(GO:0017108)
21.4	85.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
21.2	1359.0	GO:0003743	translation initiation factor activity(GO:0003743)
20.9	83.5	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
20.8	83.3	GO:0004774	succinate-CoA ligase activity(GO:0004774)
20.7	62.2	GO:0004730	pseudouridylate synthase activity(GO:0004730)
20.6	82.3	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
20.6	61.7	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
20.3	101.7	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
20.3	81.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
20.3	142.0	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
20.2	80.7	GO:0016748	succinyltransferase activity(GO:0016748)
20.2	40.3	GO:0048039	ubiquinone binding(GO:0048039)
19.8	138.8	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
19.7	59.2	GO:0032184	SUMO polymer binding(GO:0032184)
19.6	137.4	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
19.6	78.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
19.3	115.7	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
19.2	57.6	GO:0098625	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
19.0	133.2	GO:0050815	phosphoserine binding(GO:0050815)
18.9	113.3	GO:0016531	copper chaperone activity(GO:0016531)
18.6	149.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
18.5	74.2	GO:0004594	pantothenate kinase activity(GO:0004594)
18.5	55.6	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
18.5	535.9	GO:0017056	structural constituent of nuclear pore(GO:0017056)
17.6	369.7	GO:0001055	RNA polymerase II activity(GO:0001055)
17.5	227.6	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
17.0	101.7	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
16.9	84.6	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
16.9	118.2	GO:0030369	ICAM-3 receptor activity(GO:0030369)
16.8	50.4	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
16.4	213.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
16.4	196.5	GO:0031386	protein tag(GO:0031386)
16.2	259.7	GO:0008179	adenylate cyclase binding(GO:0008179)
16.1	64.5	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
16.1	64.5	GO:0004132	dCMP deaminase activity(GO:0004132)
15.9	159.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
15.9	15.9	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
15.6	109.0	GO:0019784	NEDD8-specific protease activity(GO:0019784)
15.3	45.9	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
15.2	91.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
15.2	30.3	GO:0046979	TAP2 binding(GO:0046979)
14.9	59.7	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
14.8	59.3	GO:0044388	small protein activating enzyme binding(GO:0044388)
14.8	44.4	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
14.8	29.6	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
14.7	102.8	GO:0043208	glycosphingolipid binding(GO:0043208)
14.6	43.9	GO:0004362	glutathione-disulfide reductase activity(GO:0004362)
14.6	131.1	GO:0035174	histone serine kinase activity(GO:0035174)
14.5	72.5	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
14.4	201.8	GO:0016018	cyclosporin A binding(GO:0016018)
14.3	85.5	GO:0023030	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
14.2	56.8	GO:0004566	beta-glucuronidase activity(GO:0004566)
14.0	42.1	GO:0004016	adenylate cyclase activity(GO:0004016) guanylate cyclase activity(GO:0004383)
14.0	56.0	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
14.0	83.9	GO:0051022	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
14.0	125.7	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
14.0	83.8	GO:0061649	ubiquitinated histone binding(GO:0061649)
13.8	82.5	GO:0015266	protein channel activity(GO:0015266)
13.7	109.9	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
13.6	40.8	GO:0032089	NACHT domain binding(GO:0032089)
13.4	2787.3	GO:0003735	structural constituent of ribosome(GO:0003735)
13.4	40.2	GO:0004170	dUTP diphosphatase activity(GO:0004170)
13.3	307.0	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
13.3	26.6	GO:0097677	STAT family protein binding(GO:0097677)
13.3	53.2	GO:0061676	importin-alpha family protein binding(GO:0061676)
13.2	13.2	GO:0019960	C-X3-C chemokine binding(GO:0019960)
13.2	52.8	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
13.1	564.8	GO:0061650	ubiquitin-like protein conjugating enzyme activity(GO:0061650)
13.1	52.3	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
13.1	26.1	GO:0001132	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
13.0	52.0	GO:0004743	pyruvate kinase activity(GO:0004743)
12.9	219.3	GO:0005537	mannose binding(GO:0005537)
12.9	205.8	GO:0008266	poly(U) RNA binding(GO:0008266)
12.8	128.3	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
12.8	192.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
12.8	64.0	GO:0030348	syntaxin-3 binding(GO:0030348)
12.8	319.7	GO:0008157	protein phosphatase 1 binding(GO:0008157)
12.8	38.3	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
12.7	344.0	GO:0017025	TBP-class protein binding(GO:0017025)
12.7	12.7	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
12.6	50.6	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
12.6	37.7	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
12.5	50.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
12.5	49.9	GO:0016784	3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
12.4	37.1	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
12.3	49.2	GO:0031871	proteinase activated receptor binding(GO:0031871)
12.3	24.5	GO:0071933	Arp2/3 complex binding(GO:0071933)
12.2	110.0	GO:0046790	virion binding(GO:0046790)
12.2	61.1	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
12.0	72.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
11.9	273.5	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
11.9	201.7	GO:0043495	protein anchor(GO:0043495)
11.9	23.7	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
11.8	82.4	GO:0050733	RS domain binding(GO:0050733)
11.7	70.3	GO:0048408	epidermal growth factor binding(GO:0048408)
11.7	35.1	GO:0070538	oleic acid binding(GO:0070538)
11.7	46.6	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
11.6	23.2	GO:0032143	single thymine insertion binding(GO:0032143)
11.6	58.0	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
11.6	255.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
11.6	139.0	GO:0089720	caspase binding(GO:0089720)
11.5	34.4	GO:0030984	kininogen binding(GO:0030984)
11.4	194.2	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
11.4	22.8	GO:0000403	Y-form DNA binding(GO:0000403)
11.3	45.4	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
11.3	45.1	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
11.2	67.4	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
11.2	145.8	GO:0030957	Tat protein binding(GO:0030957)
11.2	44.7	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
11.1	311.6	GO:0005123	death receptor binding(GO:0005123)
11.1	166.6	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
11.0	55.1	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
11.0	88.0	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
11.0	87.6	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
10.9	32.7	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
10.9	21.8	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
10.9	32.6	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
10.8	32.3	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
10.7	559.0	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
10.7	32.1	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
10.7	106.6	GO:0019237	centromeric DNA binding(GO:0019237)
10.7	10.7	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
10.6	116.5	GO:0030515	snoRNA binding(GO:0030515)
10.6	52.8	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
10.6	42.2	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
10.6	31.7	GO:0003978	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
10.5	42.1	GO:0016936	galactoside binding(GO:0016936)
10.5	147.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
10.5	52.6	GO:0043120	tumor necrosis factor binding(GO:0043120)
10.4	20.8	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
10.4	41.7	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
10.4	83.3	GO:0008097	5S rRNA binding(GO:0008097)
10.4	135.0	GO:0050786	RAGE receptor binding(GO:0050786)
10.3	20.7	GO:0019788	NEDD8 transferase activity(GO:0019788)
10.3	51.6	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
10.2	61.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
10.1	30.2	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
10.1	221.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
10.0	140.4	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
10.0	941.0	GO:0003697	single-stranded DNA binding(GO:0003697)
9.9	29.7	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
9.9	39.6	GO:0004348	glucosylceramidase activity(GO:0004348)
9.8	107.5	GO:0019869	chloride channel inhibitor activity(GO:0019869)
9.7	19.4	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
9.7	29.1	GO:0004756	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
9.7	29.1	GO:0032090	Pyrin domain binding(GO:0032090)
9.6	67.2	GO:0001054	RNA polymerase I activity(GO:0001054)
9.6	19.2	GO:0022884	macromolecule transmembrane transporter activity(GO:0022884)
9.6	28.7	GO:0004917	interleukin-7 receptor activity(GO:0004917)
9.6	66.9	GO:0004301	epoxide hydrolase activity(GO:0004301)
9.5	9.5	GO:0001540	beta-amyloid binding(GO:0001540)
9.5	302.7	GO:0070577	lysine-acetylated histone binding(GO:0070577)
9.4	28.3	GO:0036033	mediator complex binding(GO:0036033)
9.4	37.5	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
9.4	37.4	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
9.3	140.1	GO:0032036	myosin heavy chain binding(GO:0032036)
9.3	390.9	GO:0050699	WW domain binding(GO:0050699)
9.3	27.9	GO:0098770	FBXO family protein binding(GO:0098770)
9.3	18.6	GO:0003998	acylphosphatase activity(GO:0003998)
9.3	83.5	GO:1990226	histone methyltransferase binding(GO:1990226)
9.2	202.3	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
9.1	63.4	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
9.0	27.0	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
9.0	45.0	GO:0002046	opsin binding(GO:0002046)
9.0	17.9	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
8.9	169.7	GO:0051400	BH domain binding(GO:0051400)
8.9	62.5	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
8.9	124.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
8.9	44.3	GO:0015307	drug:proton antiporter activity(GO:0015307)
8.9	35.4	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
8.7	34.7	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
8.6	43.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
8.6	68.6	GO:1901612	cardiolipin binding(GO:1901612)
8.5	67.8	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
8.5	67.8	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
8.5	228.6	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
8.5	16.9	GO:0000828	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
8.5	194.7	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
8.3	339.1	GO:0046966	thyroid hormone receptor binding(GO:0046966)
8.2	49.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
8.2	41.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
8.2	24.6	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
8.2	8.2	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
8.2	32.8	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
8.1	80.8	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
8.0	8.0	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
8.0	32.1	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
8.0	47.9	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
7.7	15.4	GO:0042979	ornithine decarboxylase activator activity(GO:0042978) ornithine decarboxylase regulator activity(GO:0042979)
7.6	30.6	GO:0052827	inositol pentakisphosphate phosphatase activity(GO:0052827)
7.6	15.3	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
7.6	152.4	GO:0008327	methyl-CpG binding(GO:0008327)
7.5	52.6	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
7.4	44.4	GO:0035500	MH2 domain binding(GO:0035500)
7.3	29.4	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
7.3	431.4	GO:0019003	GDP binding(GO:0019003)
7.3	21.9	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
7.3	29.1	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
7.3	246.6	GO:0044183	protein binding involved in protein folding(GO:0044183)
7.3	7.3	GO:0001727	lipid kinase activity(GO:0001727)
7.2	28.9	GO:0015140	malate transmembrane transporter activity(GO:0015140)
7.1	42.7	GO:0033989	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
7.1	28.4	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
7.1	78.1	GO:0017070	U6 snRNA binding(GO:0017070)
7.1	63.6	GO:0050700	CARD domain binding(GO:0050700)
7.0	7.0	GO:0019961	interferon binding(GO:0019961)
6.9	172.1	GO:0031489	myosin V binding(GO:0031489)
6.8	27.3	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
6.6	6.6	GO:0008384	IkappaB kinase activity(GO:0008384)
6.6	46.5	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
6.6	39.8	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
6.6	19.7	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
6.5	39.1	GO:0019776	Atg8 ligase activity(GO:0019776)
6.4	32.0	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
6.2	49.8	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
6.2	18.6	GO:0004766	spermidine synthase activity(GO:0004766)
6.2	43.5	GO:0035197	siRNA binding(GO:0035197)
6.2	43.4	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
6.2	24.8	GO:0000400	four-way junction DNA binding(GO:0000400)
6.2	37.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
6.2	308.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
6.2	24.7	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
6.1	6.1	GO:0004913	interleukin-4 receptor activity(GO:0004913)
6.1	169.5	GO:0001671	ATPase activator activity(GO:0001671)
6.0	6.0	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
6.0	107.9	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
6.0	35.8	GO:0047685	amine sulfotransferase activity(GO:0047685)
6.0	77.5	GO:0003688	DNA replication origin binding(GO:0003688)
5.9	76.7	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
5.9	118.0	GO:0042288	MHC class I protein binding(GO:0042288)
5.8	40.6	GO:0070087	chromo shadow domain binding(GO:0070087)
5.8	34.6	GO:1990254	keratin filament binding(GO:1990254)
5.8	178.3	GO:0031492	nucleosomal DNA binding(GO:0031492)
5.7	80.3	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
5.7	17.1	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
5.7	39.9	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
5.7	11.4	GO:1990837	sequence-specific double-stranded DNA binding(GO:1990837)
5.5	16.6	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
5.5	16.6	GO:0001181	transcription factor activity, core RNA polymerase I binding(GO:0001181)
5.5	27.6	GO:0004689	phosphorylase kinase activity(GO:0004689)
5.5	16.4	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
5.4	326.3	GO:0008186	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
5.4	16.3	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
5.4	43.4	GO:0005522	profilin binding(GO:0005522)
5.4	509.6	GO:0043130	ubiquitin binding(GO:0043130)
5.4	10.8	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
5.3	58.6	GO:0004312	fatty acid synthase activity(GO:0004312)
5.3	69.3	GO:0070628	proteasome binding(GO:0070628)
5.3	26.5	GO:0017159	pantetheine hydrolase activity(GO:0017159)
5.3	116.6	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
5.3	31.7	GO:0003796	lysozyme activity(GO:0003796)
5.3	15.9	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
5.3	31.7	GO:0003872	6-phosphofructokinase activity(GO:0003872)
5.3	47.5	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
5.3	47.4	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
5.3	15.8	GO:0044549	GTP cyclohydrolase binding(GO:0044549)
5.2	105.0	GO:0070064	proline-rich region binding(GO:0070064)
5.2	99.7	GO:0023026	MHC class II protein complex binding(GO:0023026)
5.2	15.7	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
5.2	15.6	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
5.2	26.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
5.2	93.3	GO:0097602	cullin family protein binding(GO:0097602)
5.2	31.1	GO:0036310	annealing helicase activity(GO:0036310)
5.2	36.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
5.2	82.4	GO:0043422	protein kinase B binding(GO:0043422)
5.1	138.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
5.1	20.5	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
5.1	15.3	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
5.1	15.3	GO:0030613	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
5.1	15.3	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
5.1	126.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
5.0	40.4	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
5.0	15.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
5.0	20.1	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
5.0	90.5	GO:0031404	chloride ion binding(GO:0031404)
5.0	14.9	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
5.0	10.0	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
5.0	34.8	GO:0004459	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
4.9	9.8	GO:0032552	deoxyribonucleotide binding(GO:0032552)
4.9	24.5	GO:1990460	leptin receptor binding(GO:1990460)
4.9	24.5	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
4.9	39.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
4.9	136.8	GO:0000993	RNA polymerase II core binding(GO:0000993)
4.8	33.9	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
4.8	101.6	GO:0008242	omega peptidase activity(GO:0008242)
4.8	19.3	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
4.8	19.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
4.7	18.9	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
4.7	542.1	GO:0047485	protein N-terminus binding(GO:0047485)
4.7	47.1	GO:0019534	toxin transporter activity(GO:0019534)
4.7	204.9	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
4.6	60.4	GO:0031491	nucleosome binding(GO:0031491)
4.6	166.5	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
4.6	23.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
4.6	13.8	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
4.6	442.1	GO:0008565	protein transporter activity(GO:0008565)
4.5	13.6	GO:0004914	interleukin-5 receptor activity(GO:0004914)
4.5	35.6	GO:0070878	primary miRNA binding(GO:0070878)
4.5	17.8	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
4.4	44.3	GO:0048156	tau protein binding(GO:0048156)
4.4	79.1	GO:0017049	GTP-Rho binding(GO:0017049)
4.4	21.8	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
4.4	43.5	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
4.4	95.8	GO:0036002	pre-mRNA binding(GO:0036002)
4.3	8.7	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
4.3	56.5	GO:0019992	diacylglycerol binding(GO:0019992)
4.3	90.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
4.3	8.6	GO:0070644	vitamin D response element binding(GO:0070644)
4.3	17.2	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
4.3	21.5	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
4.3	8.6	GO:0004167	dopachrome isomerase activity(GO:0004167)
4.3	76.8	GO:0010857	calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
4.3	208.5	GO:0035064	methylated histone binding(GO:0035064)
4.2	12.7	GO:0048030	disaccharide binding(GO:0048030)
4.2	8.4	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
4.2	75.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
4.2	46.0	GO:0050321	tau-protein kinase activity(GO:0050321)
4.2	8.3	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
4.2	12.5	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
4.1	153.5	GO:0005484	SNAP receptor activity(GO:0005484)
4.1	173.1	GO:0019212	phosphatase inhibitor activity(GO:0019212)
4.1	102.8	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
4.1	57.1	GO:0030228	lipoprotein particle receptor activity(GO:0030228)
4.0	28.0	GO:0004849	uridine kinase activity(GO:0004849)
3.9	19.6	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
3.9	47.1	GO:0003680	AT DNA binding(GO:0003680)
3.9	70.1	GO:0004177	aminopeptidase activity(GO:0004177)
3.9	11.7	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
3.9	7.7	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
3.9	223.7	GO:0003725	double-stranded RNA binding(GO:0003725)
3.8	26.7	GO:0030274	LIM domain binding(GO:0030274)
3.8	11.3	GO:0004958	prostaglandin F receptor activity(GO:0004958)
3.8	56.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
3.7	7.5	GO:0050211	procollagen galactosyltransferase activity(GO:0050211)
3.7	788.0	GO:0051015	actin filament binding(GO:0051015)
3.7	22.3	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
3.7	22.1	GO:0019238	cyclohydrolase activity(GO:0019238)
3.7	14.7	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
3.7	14.7	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
3.6	58.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
3.6	105.3	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
3.6	3.6	GO:0097001	ceramide binding(GO:0097001)
3.6	14.4	GO:0004850	uridine phosphorylase activity(GO:0004850)
3.6	28.7	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
3.6	10.8	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
3.6	39.5	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
3.6	114.5	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
3.6	3.6	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
3.5	7.1	GO:0010698	acetyltransferase activator activity(GO:0010698)
3.5	21.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
3.5	96.9	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)
3.4	10.3	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
3.4	30.5	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
3.4	10.1	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
3.4	57.2	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
3.3	9.9	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
3.3	88.6	GO:0005540	hyaluronic acid binding(GO:0005540)
3.1	22.0	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
3.1	25.1	GO:0034594	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
3.1	25.0	GO:0004470	malic enzyme activity(GO:0004470)
3.1	3.1	GO:0099609	microtubule lateral binding(GO:0099609)
3.1	12.4	GO:0003938	IMP dehydrogenase activity(GO:0003938)
3.1	18.5	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
3.1	27.7	GO:0019213	deacetylase activity(GO:0019213)
3.0	33.4	GO:0032395	MHC class II receptor activity(GO:0032395)
3.0	9.1	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
3.0	15.0	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
3.0	77.7	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
3.0	50.7	GO:0042974	retinoic acid receptor binding(GO:0042974)
3.0	20.9	GO:0004920	interleukin-10 receptor activity(GO:0004920)
3.0	6.0	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
3.0	3197.5	GO:0003723	RNA binding(GO:0003723)
3.0	67.9	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
2.9	66.8	GO:0017134	fibroblast growth factor binding(GO:0017134)
2.9	8.7	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
2.8	2.8	GO:0051185	coenzyme transporter activity(GO:0051185)
2.8	42.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
2.8	11.3	GO:0070051	fibrinogen binding(GO:0070051)
2.8	30.9	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
2.8	14.0	GO:0032407	mismatch repair complex binding(GO:0032404) MutSalpha complex binding(GO:0032407)
2.7	8.2	GO:0004796	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
2.7	8.2	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.7	30.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
2.7	26.9	GO:0046527	glucosyltransferase activity(GO:0046527)
2.7	45.7	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
2.7	10.7	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
2.7	2.7	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
2.7	8.0	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
2.7	34.6	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
2.6	68.5	GO:0031210	phosphatidylcholine binding(GO:0031210)
2.6	36.3	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
2.6	18.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
2.6	20.7	GO:1990763	arrestin family protein binding(GO:1990763)
2.6	5.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
2.5	38.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
2.5	12.7	GO:0005134	interleukin-2 receptor binding(GO:0005134)
2.5	38.1	GO:0000149	SNARE binding(GO:0000149)
2.5	5.0	GO:0048406	nerve growth factor binding(GO:0048406)
2.5	66.6	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
2.4	55.8	GO:0051879	Hsp90 protein binding(GO:0051879)
2.4	11.9	GO:0051861	glycolipid binding(GO:0051861)
2.4	149.4	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
2.3	83.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
2.3	6.9	GO:0019981	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
2.3	6.9	GO:0003953	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
2.3	27.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
2.2	129.4	GO:0051082	unfolded protein binding(GO:0051082)
2.2	15.6	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
2.2	15.6	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.2	24.3	GO:0005131	growth hormone receptor binding(GO:0005131)
2.2	10.8	GO:0032050	clathrin heavy chain binding(GO:0032050)
2.1	6.4	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
2.1	40.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
2.1	100.7	GO:0017080	sodium channel regulator activity(GO:0017080)
2.0	4.0	GO:0001849	complement component C1q binding(GO:0001849)
2.0	5.9	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
1.9	5.8	GO:0030366	molybdopterin synthase activity(GO:0030366)
1.9	11.5	GO:0015288	porin activity(GO:0015288)
1.9	32.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
1.9	13.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
1.9	9.4	GO:0019863	IgE binding(GO:0019863)
1.9	20.6	GO:0016413	O-acetyltransferase activity(GO:0016413)
1.8	71.1	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
1.8	5.5	GO:0033149	FFAT motif binding(GO:0033149)
1.8	5.5	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
1.8	14.5	GO:0035325	Toll-like receptor binding(GO:0035325)
1.8	9.0	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
1.8	3.6	GO:0016417	S-acyltransferase activity(GO:0016417)
1.8	7.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
1.8	10.8	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
1.8	1.8	GO:0048185	activin binding(GO:0048185)
1.8	28.7	GO:0048365	Rac GTPase binding(GO:0048365)
1.8	12.4	GO:0004180	carboxypeptidase activity(GO:0004180)
1.8	12.3	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
1.7	5.1	GO:0030226	apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.7	8.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.7	20.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
1.7	5.0	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
1.7	25.1	GO:0042605	peptide antigen binding(GO:0042605)
1.7	5.0	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.6	6.5	GO:0000182	rDNA binding(GO:0000182)
1.6	222.3	GO:0005178	integrin binding(GO:0005178)
1.6	8.0	GO:0070840	dynein complex binding(GO:0070840)
1.6	8.0	GO:0034452	dynactin binding(GO:0034452)
1.6	4.7	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
1.6	4.7	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
1.6	9.3	GO:0008046	axon guidance receptor activity(GO:0008046)
1.5	3.1	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
1.5	9.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
1.5	6.1	GO:0001047	core promoter binding(GO:0001047)
1.5	33.2	GO:0008235	metalloexopeptidase activity(GO:0008235)
1.5	80.0	GO:0042393	histone binding(GO:0042393)
1.5	25.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
1.5	2.9	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.5	2.9	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.4	13.0	GO:0043560	insulin receptor substrate binding(GO:0043560)
1.4	76.7	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
1.4	11.5	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.4	18.6	GO:0008536	Ran GTPase binding(GO:0008536)
1.4	8.6	GO:0035800	deubiquitinase activator activity(GO:0035800)
1.4	11.4	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
1.4	59.7	GO:0008276	protein methyltransferase activity(GO:0008276)
1.4	7.0	GO:0047820	D-glutamate cyclase activity(GO:0047820)
1.4	5.6	GO:0043515	kinetochore binding(GO:0043515)
1.4	5.5	GO:0047023	androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
1.4	20.8	GO:0004602	glutathione peroxidase activity(GO:0004602)
1.4	4.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
1.4	13.5	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
1.3	4.0	GO:0030898	actin-dependent ATPase activity(GO:0030898)
1.3	9.2	GO:0070403	NAD+ binding(GO:0070403)
1.3	11.7	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
1.3	14.2	GO:0033038	bitter taste receptor activity(GO:0033038)
1.3	12.8	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
1.3	25.5	GO:0042813	Wnt-activated receptor activity(GO:0042813)
1.3	17.8	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
1.3	1.3	GO:0034186	apolipoprotein A-I binding(GO:0034186)
1.3	3.8	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
1.2	9.8	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.2	3.7	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.2	3.7	GO:0023023	MHC protein complex binding(GO:0023023)
1.2	256.4	GO:0003924	GTPase activity(GO:0003924)
1.2	7.1	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.2	5.9	GO:0004771	sterol esterase activity(GO:0004771)
1.2	86.5	GO:0003777	microtubule motor activity(GO:0003777)
1.2	2.3	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
1.2	5.8	GO:0010465	nerve growth factor receptor activity(GO:0010465)
1.2	2.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
1.2	10.4	GO:0004985	opioid receptor activity(GO:0004985)
1.2	57.8	GO:0034987	immunoglobulin receptor binding(GO:0034987)
1.1	6.6	GO:0039552	RIG-I binding(GO:0039552)
1.1	6.6	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
1.1	14.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
1.1	3.3	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
1.1	14.1	GO:0051059	NF-kappaB binding(GO:0051059)
1.1	4.3	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
1.1	8.5	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.1	3.2	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
1.1	3.2	GO:0005000	vasopressin receptor activity(GO:0005000)
1.0	2.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.0	4.2	GO:0031208	POZ domain binding(GO:0031208)
1.0	4.2	GO:0016499	orexin receptor activity(GO:0016499)
1.0	6.2	GO:0035374	chondroitin sulfate binding(GO:0035374)
1.0	19.7	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
1.0	50.8	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
1.0	39.1	GO:0005507	copper ion binding(GO:0005507)
1.0	10.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.0	4.1	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
1.0	14.2	GO:0030280	structural constituent of epidermis(GO:0030280)
1.0	7.1	GO:0043426	MRF binding(GO:0043426)
1.0	63.2	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
1.0	2.9	GO:0004465	lipoprotein lipase activity(GO:0004465)
1.0	3.8	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.9	3.8	GO:0008420	CTD phosphatase activity(GO:0008420)
0.9	3.6	GO:0017018	myosin phosphatase activity(GO:0017018)
0.9	18.8	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.9	1.8	GO:0001163	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.9	15.1	GO:0071889	14-3-3 protein binding(GO:0071889)
0.9	2.6	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.9	10.6	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.8	1.7	GO:0043532	angiostatin binding(GO:0043532)
0.8	5.6	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.8	48.8	GO:0032947	protein complex scaffold(GO:0032947)
0.8	2.4	GO:0043559	insulin binding(GO:0043559)
0.8	18.8	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.8	9.3	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.8	17.0	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.8	22.8	GO:0002039	p53 binding(GO:0002039)
0.7	0.7	GO:0004521	endoribonuclease activity(GO:0004521)
0.7	5.7	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.7	6.4	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.7	15.4	GO:0042169	SH2 domain binding(GO:0042169)
0.7	12.6	GO:0050811	GABA receptor binding(GO:0050811)
0.7	170.1	GO:0008236	serine-type peptidase activity(GO:0008236)
0.7	2.0	GO:0098821	BMP receptor activity(GO:0098821)
0.7	3.3	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.7	16.0	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.7	5.3	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.7	1.3	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.6	7.7	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.6	1.9	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.6	6.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6	1.9	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.6	1.8	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.6	8.4	GO:0051087	chaperone binding(GO:0051087)
0.6	1.8	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.6	1.2	GO:0016886	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) ligase activity, forming phosphoric ester bonds(GO:0016886)
0.6	4.7	GO:0042731	PH domain binding(GO:0042731)
0.6	10.5	GO:0051117	ATPase binding(GO:0051117)
0.6	10.9	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.6	2.2	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.6	1.7	GO:0004603	phenylethanolamine N-methyltransferase activity(GO:0004603)
0.5	2.2	GO:0032190	acrosin binding(GO:0032190)
0.5	4.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.5	8.9	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.5	2.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.5	2.0	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.5	3.0	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.5	1.0	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.5	1.9	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.5	1.9	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5	1.9	GO:0008518	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.5	1.4	GO:0042289	MHC class II protein binding(GO:0042289)
0.5	0.5	GO:0097027	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) ubiquitin-protein transferase activator activity(GO:0097027)
0.4	1.8	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4	6.1	GO:0019864	IgG binding(GO:0019864)
0.4	3.0	GO:0008199	ferric iron binding(GO:0008199)
0.4	2.2	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.4	1.7	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.4	5.0	GO:0031072	heat shock protein binding(GO:0031072)
0.4	4.4	GO:0030295	protein kinase activator activity(GO:0030295)
0.4	2.0	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.4	2.7	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.4	2.3	GO:0005518	collagen binding(GO:0005518)
0.4	1.4	GO:0004522	ribonuclease A activity(GO:0004522)
0.3	9.8	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.3	6.6	GO:0017075	syntaxin-1 binding(GO:0017075)
0.3	3.8	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3	2.4	GO:0042834	peptidoglycan binding(GO:0042834)
0.3	2.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.3	6.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.3	101.7	GO:0019900	kinase binding(GO:0019900)
0.3	29.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.3	8.9	GO:0015485	cholesterol binding(GO:0015485)
0.3	0.9	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3	2.3	GO:0008172	S-methyltransferase activity(GO:0008172)
0.3	2.7	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.3	1.1	GO:0004966	galanin receptor activity(GO:0004966)
0.3	10.5	GO:0009055	electron carrier activity(GO:0009055)
0.3	1.0	GO:0045295	gamma-catenin binding(GO:0045295)
0.3	1.5	GO:0004084	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2	3.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2	0.7	GO:0003883	CTP synthase activity(GO:0003883)
0.2	2.6	GO:0042043	neurexin family protein binding(GO:0042043)
0.2	4.9	GO:0019956	chemokine binding(GO:0019956)
0.2	0.4	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	3.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.2	27.8	GO:0030246	carbohydrate binding(GO:0030246)
0.2	1.2	GO:0015250	water channel activity(GO:0015250)
0.2	5.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2	4.2	GO:0003774	motor activity(GO:0003774)
0.2	60.3	GO:0003712	transcription cofactor activity(GO:0003712)
0.2	1.0	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.2	1.3	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2	1.4	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2	0.9	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.2	1.2	GO:0042923	neuropeptide binding(GO:0042923)
0.1	0.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	3.7	GO:0043621	protein self-association(GO:0043621)
0.1	2.0	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	3.0	GO:0030276	clathrin binding(GO:0030276)
0.1	10.7	GO:0005262	calcium channel activity(GO:0005262)
0.1	13.5	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.1	1.8	GO:0042805	actinin binding(GO:0042805)
0.1	0.6	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	0.5	GO:0008301	DNA binding, bending(GO:0008301)
0.1	1.6	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	1.1	GO:0016836	hydro-lyase activity(GO:0016836)
0.1	2.1	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.1	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	0.3	GO:0015232	heme transporter activity(GO:0015232)
0.1	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.4	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.5	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.8	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.7	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.8	GO:0097110	scaffold protein binding(GO:0097110)
0.0	1.9	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.7	132.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
13.9	582.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
12.8	38.5	PID TRAIL PATHWAY	TRAIL signaling pathway
11.7	349.9	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
11.1	321.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
10.4	855.8	PID RAC1 PATHWAY	RAC1 signaling pathway
10.0	658.4	PID ATR PATHWAY	ATR signaling pathway
9.8	9.8	PID S1P S1P1 PATHWAY	S1P1 pathway
8.3	698.3	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
8.1	32.5	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
8.1	226.0	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
8.0	393.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
7.8	209.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
7.7	478.4	PID AURORA B PATHWAY	Aurora B signaling
7.3	7.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
7.0	105.3	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
7.0	7.0	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
6.8	68.5	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
6.7	517.6	PID ILK PATHWAY	Integrin-linked kinase signaling
6.6	629.8	PID E2F PATHWAY	E2F transcription factor network
6.6	488.1	PID P53 REGULATION PATHWAY	p53 pathway
6.4	238.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
6.4	255.8	PID PLK1 PATHWAY	PLK1 signaling events
6.1	201.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
6.0	366.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
5.9	35.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
5.8	58.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
5.8	219.4	PID ALK1 PATHWAY	ALK1 signaling events
5.4	185.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
5.3	112.2	PID ARF 3PATHWAY	Arf1 pathway
5.2	20.7	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
4.8	154.7	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
4.6	91.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
4.5	8.9	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
4.4	440.6	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
4.3	95.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
3.9	147.4	PID TNF PATHWAY	TNF receptor signaling pathway
3.8	19.2	PID ERBB4 PATHWAY	ErbB4 signaling events
3.8	95.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
3.8	176.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
3.8	108.9	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
3.7	66.9	PID AURORA A PATHWAY	Aurora A signaling
3.5	60.0	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
3.3	16.6	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
3.3	32.9	PID ATM PATHWAY	ATM pathway
3.2	95.7	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
3.1	132.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
3.1	75.0	PID IL1 PATHWAY	IL1-mediated signaling events
3.1	3.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
3.0	71.9	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
2.9	34.9	PID S1P S1P4 PATHWAY	S1P4 pathway
2.8	68.2	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
2.8	33.6	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
2.7	44.0	PID CD40 PATHWAY	CD40/CD40L signaling
2.6	49.4	PID IFNG PATHWAY	IFN-gamma pathway
2.6	124.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
2.6	63.9	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
2.5	17.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
2.5	211.4	PID CMYB PATHWAY	C-MYB transcription factor network
2.4	76.9	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
2.4	43.2	PID INSULIN PATHWAY	Insulin Pathway
2.4	343.1	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
2.3	161.9	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
2.3	78.3	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
2.3	126.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
2.3	18.0	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
2.2	20.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
2.2	13.3	PID FAS PATHWAY	FAS (CD95) signaling pathway
2.0	14.3	ST JNK MAPK PATHWAY	JNK MAPK Pathway
2.0	69.0	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
1.9	23.3	PID IL3 PATHWAY	IL3-mediated signaling events
1.8	11.0	ST G ALPHA S PATHWAY	G alpha s Pathway
1.8	3.6	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
1.8	111.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
1.7	38.1	PID ATF2 PATHWAY	ATF-2 transcription factor network
1.7	58.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
1.7	41.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.6	68.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
1.6	65.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
1.4	33.8	PID IL4 2PATHWAY	IL4-mediated signaling events
1.3	17.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
1.3	20.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
1.3	28.9	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
1.2	43.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
1.2	25.4	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
1.2	7.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
1.1	3.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
1.1	14.0	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
1.1	15.9	PID IL2 1PATHWAY	IL2-mediated signaling events
1.0	11.4	PID FOXO PATHWAY	FoxO family signaling
0.9	25.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.9	5.3	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.9	9.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.8	32.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.8	8.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.8	6.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.8	25.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.7	12.8	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.7	17.3	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.7	2.6	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.6	5.7	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.6	20.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.6	4.9	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.6	5.0	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.5	12.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.5	3.8	PID REELIN PATHWAY	Reelin signaling pathway
0.5	21.2	PID P73PATHWAY	p73 transcription factor network
0.5	6.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.5	13.4	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.4	2.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.4	10.6	PID CDC42 PATHWAY	CDC42 signaling events
0.4	21.8	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.4	5.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.4	89.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4	1.6	PID BARD1 PATHWAY	BARD1 signaling events
0.4	7.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.4	1.5	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.3	3.9	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.3	4.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.2	1.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.2	3.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	1.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	3.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	0.9	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.6	PID PI3KCI PATHWAY	Class I PI3K signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
39.5	632.7	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
36.5	328.6	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
35.3	2609.8	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
26.4	263.7	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
25.6	920.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
24.4	391.0	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
24.1	1833.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
23.9	23.9	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
22.2	642.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
21.9	131.4	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
21.8	522.0	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
21.0	2807.8	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
20.9	480.8	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
20.9	20.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
18.8	469.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
18.2	382.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
17.8	285.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
16.7	699.5	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
16.4	540.3	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
16.4	523.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
16.0	224.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
15.1	225.9	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
15.0	180.4	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
14.8	575.5	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
14.7	29.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
14.5	1489.3	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
13.7	219.8	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
13.2	383.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
12.7	202.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
12.6	390.4	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
12.2	24.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
12.1	242.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
11.8	695.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
11.7	11.7	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
11.5	368.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
10.5	52.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
10.4	352.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
10.2	193.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
10.0	129.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
10.0	328.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
9.9	168.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
9.8	254.5	REACTOME KINESINS	Genes involved in Kinesins
9.7	164.8	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
9.7	774.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
9.4	131.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
9.3	315.2	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
9.2	174.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
9.1	63.4	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
8.9	384.2	REACTOME TRANSLATION	Genes involved in Translation
8.7	443.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
8.7	182.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
8.6	129.7	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
8.4	160.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
8.4	218.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
8.3	247.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
7.9	198.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
7.7	271.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
7.6	428.3	REACTOME G1 PHASE	Genes involved in G1 Phase
7.6	84.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
7.6	152.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
7.5	193.9	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
7.0	49.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
7.0	20.9	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
6.8	47.8	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
6.6	138.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
6.5	52.4	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
6.4	90.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
6.4	147.4	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
6.2	55.8	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
6.1	128.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
6.1	54.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
5.9	465.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
5.8	23.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
5.7	17.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
5.6	118.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
5.6	223.5	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
5.5	154.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
5.4	784.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
5.3	159.4	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
5.1	97.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
5.0	20.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
5.0	15.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
5.0	119.7	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
4.9	88.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
4.9	39.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
4.8	62.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
4.7	135.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
4.3	78.2	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
4.3	60.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
4.2	62.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
4.2	29.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
4.2	128.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
4.0	16.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
4.0	4.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
4.0	158.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
4.0	71.4	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
3.8	65.3	REACTOME METABOLISM OF NUCLEOTIDES	Genes involved in Metabolism of nucleotides
3.8	68.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
3.7	85.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
3.6	36.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
3.6	36.0	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
3.6	251.0	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
3.6	74.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
3.5	14.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
3.5	80.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
3.4	20.7	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
3.4	61.5	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
3.3	26.7	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
3.3	23.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
3.1	144.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
3.1	9.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
3.1	3.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
3.0	127.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
3.0	32.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
3.0	76.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
2.9	26.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
2.8	69.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
2.8	82.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
2.7	155.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
2.7	32.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
2.7	13.4	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
2.7	152.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
2.7	37.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
2.7	8.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
2.6	287.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
2.6	41.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
2.5	42.2	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
2.4	59.3	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
2.3	29.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
2.2	33.6	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
2.2	45.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
2.1	55.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
1.9	76.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
1.8	38.8	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
1.8	20.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
1.7	27.8	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
1.7	34.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
1.7	15.3	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
1.6	8.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
1.6	11.2	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
1.6	68.3	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
1.6	84.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
1.5	60.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
1.5	90.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
1.4	208.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
1.4	66.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.3	18.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
1.3	97.0	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
1.3	6.4	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
1.3	1.3	REACTOME SIGNALING BY INSULIN RECEPTOR	Genes involved in Signaling by Insulin receptor
1.2	12.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
1.2	56.3	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
1.2	18.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
1.1	3.4	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
1.1	25.0	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
1.1	26.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
1.0	2.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
1.0	39.6	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
1.0	6.7	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
1.0	17.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.9	16.4	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.8	12.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.7	11.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.7	2.2	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.7	12.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.7	4.8	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.6	20.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.5	5.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.5	31.0	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.3	5.7	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.3	5.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.3	6.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.3	0.8	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.3	2.7	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.3	7.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	2.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.2	4.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	0.7	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.2	8.2	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.2	21.9	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.2	8.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	1.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	4.4	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1	0.4	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	1.0	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)