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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ELF2_GABPA_ELF5

Z-value: 6.22

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Transcription factors associated with ELF2_GABPA_ELF5

Gene Symbol Gene ID Gene Info
ENSG00000109381.15 E74 like ETS transcription factor 2
ENSG00000154727.6 GA binding protein transcription factor subunit alpha
ENSG00000135374.5 E74 like ETS transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ELF2hg19_v2_chr4_-_140005443_1400056500.393.4e-09Click!
ELF5hg19_v2_chr11_-_34535332_34535352-0.321.3e-06Click!
GABPAhg19_v2_chr21_+_27107672_271076980.305.7e-06Click!

Activity profile of ELF2_GABPA_ELF5 motif

Sorted Z-values of ELF2_GABPA_ELF5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_32687971 250.23 ENST00000373586.1
eukaryotic translation initiation factor 3, subunit I
chr20_-_49575058 227.86 ENST00000371584.4
ENST00000371583.5
ENST00000413082.1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr12_-_110888103 205.96 ENST00000426440.1
ENST00000228825.7
actin related protein 2/3 complex, subunit 3, 21kDa
chr14_-_69864993 203.36 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr2_-_73964447 198.19 ENST00000272424.5
ENST00000409716.2
ENST00000318190.7
TP53RK binding protein
chr12_+_69080734 184.07 ENST00000378905.2
nucleoporin 107kDa
chr1_+_40506392 163.00 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr7_+_141438393 155.66 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
single-stranded DNA binding protein 1, mitochondrial
chr5_+_110074685 154.37 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr19_-_10450287 150.78 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr20_-_2451395 150.40 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
small nuclear ribonucleoprotein polypeptides B and B1
chr10_+_12238171 142.39 ENST00000378900.2
ENST00000442050.1
cell division cycle 123
chr13_-_31191642 142.10 ENST00000405805.1
high mobility group box 1
chr18_+_657733 138.60 ENST00000323250.5
ENST00000323224.7
thymidylate synthetase
chr20_-_49575081 136.74 ENST00000371588.5
ENST00000371582.4
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr7_-_5569588 133.94 ENST00000417101.1
actin, beta
chr2_+_198380763 133.60 ENST00000448447.2
ENST00000409360.1
MOB family member 4, phocein
chr2_+_65454863 132.38 ENST00000260641.5
ARP2 actin-related protein 2 homolog (yeast)
chr3_-_131221790 131.73 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr22_-_36924944 131.70 ENST00000405442.1
ENST00000402116.1
eukaryotic translation initiation factor 3, subunit D
chr7_-_7680601 131.55 ENST00000396682.2
replication protein A3, 14kDa
chr22_+_24951436 131.53 ENST00000215829.3
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr1_+_203830703 129.90 ENST00000414487.2
small nuclear ribonucleoprotein polypeptide E
chr22_-_36925186 129.79 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
eukaryotic translation initiation factor 3, subunit D
chr1_+_40505891 128.01 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr2_+_65454926 127.68 ENST00000542850.1
ENST00000377982.4
ARP2 actin-related protein 2 homolog (yeast)
chr11_-_67169253 126.47 ENST00000527663.1
ENST00000312989.7
protein phosphatase 1, catalytic subunit, alpha isozyme
chr11_-_67169265 125.84 ENST00000358239.4
ENST00000376745.4
protein phosphatase 1, catalytic subunit, alpha isozyme
chr10_-_43892668 123.16 ENST00000544000.1
heterogeneous nuclear ribonucleoprotein F
chr10_+_43278217 120.88 ENST00000374518.5
BMS1 ribosome biogenesis factor
chr10_+_12237924 120.74 ENST00000429258.2
ENST00000281141.4
cell division cycle 123
chrX_-_153775426 120.64 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr2_-_37458749 120.13 ENST00000234170.5
CCAAT/enhancer binding protein (C/EBP), zeta
chr5_+_167913450 118.72 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chr11_+_32605350 118.61 ENST00000531120.1
ENST00000524896.1
ENST00000323213.5
eukaryotic translation initiation factor 3, subunit M
chr4_+_71554196 117.14 ENST00000254803.2
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr1_+_84944926 117.02 ENST00000370656.1
ENST00000370654.5
ribosome production factor 1 homolog (S. cerevisiae)
chr17_+_57784997 116.39 ENST00000537567.1
ENST00000539763.1
ENST00000587945.1
ENST00000536180.1
ENST00000589823.2
ENST00000592106.1
ENST00000591315.1
ENST00000545362.1
vacuole membrane protein 1
chr2_-_230786619 116.17 ENST00000389045.3
ENST00000409677.1
thyroid hormone receptor interactor 12
chr2_-_99952769 115.70 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
thioredoxin domain containing 9
chr14_+_35761580 115.70 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr11_+_75110530 115.59 ENST00000531188.1
ENST00000530164.1
ENST00000422465.2
ENST00000278572.6
ENST00000534440.1
ENST00000527446.1
ENST00000526608.1
ENST00000527273.1
ENST00000524851.1
ribosomal protein S3
chr21_-_33984888 114.14 ENST00000382549.4
ENST00000540881.1
chromosome 21 open reading frame 59
chr21_-_33985127 113.96 ENST00000290155.3
chromosome 21 open reading frame 59
chr5_-_140700322 113.64 ENST00000313368.5
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr11_-_64084959 113.52 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr1_-_165738072 112.73 ENST00000481278.1
transmembrane and coiled-coil domains 1
chr10_-_43904235 111.88 ENST00000356053.3
heterogeneous nuclear ribonucleoprotein F
chr11_-_64085533 111.75 ENST00000544844.1
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr20_+_16710606 111.66 ENST00000377943.5
ENST00000246071.6
small nuclear ribonucleoprotein polypeptide B
chr1_+_93811438 111.53 ENST00000370272.4
ENST00000370267.1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr21_-_33984865 111.30 ENST00000458138.1
chromosome 21 open reading frame 59
chr19_+_13261216 111.05 ENST00000587885.1
ENST00000292433.3
immediate early response 2
chr12_+_69979113 110.63 ENST00000299300.6
chaperonin containing TCP1, subunit 2 (beta)
chr21_-_33984456 110.00 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
Uncharacterized protein
chromosome 21 open reading frame 59
chr7_+_141438118 109.76 ENST00000265304.6
ENST00000498107.1
ENST00000467681.1
ENST00000465582.1
ENST00000463093.1
single-stranded DNA binding protein 1, mitochondrial
chr17_-_57784755 109.48 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
peptidyl-tRNA hydrolase 2
chr16_+_30087288 109.04 ENST00000279387.7
ENST00000562664.1
ENST00000562222.1
protein phosphatase 4, catalytic subunit
chr19_-_51875894 109.03 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr8_-_55014415 108.27 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
lysophospholipase I
chr3_-_186524234 108.09 ENST00000418288.1
ENST00000296273.2
replication factor C (activator 1) 4, 37kDa
chr14_+_35761540 107.49 ENST00000261479.4
proteasome (prosome, macropain) subunit, alpha type, 6
chr12_-_112856623 107.43 ENST00000551291.2
ribosomal protein L6
chr2_+_118572226 107.22 ENST00000263239.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr3_-_64009102 107.16 ENST00000478185.1
ENST00000482510.1
ENST00000497323.1
ENST00000492933.1
ENST00000295901.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr17_-_8113542 106.69 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr11_+_62529008 106.57 ENST00000301788.7
ENST00000533442.1
polymerase (RNA) II (DNA directed) polypeptide G
chr6_-_31704282 106.46 ENST00000375784.3
ENST00000375779.2
chloride intracellular channel 1
chr6_-_31926629 104.93 ENST00000375425.5
ENST00000426722.1
ENST00000441998.1
ENST00000444811.2
ENST00000375429.3
negative elongation factor complex member E
chr1_-_155990580 104.88 ENST00000531917.1
ENST00000480567.1
ENST00000526212.1
ENST00000529008.1
ENST00000496742.1
ENST00000295702.4
signal sequence receptor, beta (translocon-associated protein beta)
chr5_+_892745 104.39 ENST00000166345.3
thyroid hormone receptor interactor 13
chr7_+_5085452 103.50 ENST00000353796.3
ENST00000396912.1
ENST00000396904.2
RB-associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr11_+_65770227 103.39 ENST00000527348.1
barrier to autointegration factor 1
chr11_-_58345569 102.48 ENST00000528954.1
ENST00000528489.1
leupaxin
chr10_-_43904608 102.42 ENST00000337970.3
heterogeneous nuclear ribonucleoprotein F
chr18_+_3247413 102.28 ENST00000579226.1
ENST00000217652.3
myosin, light chain 12A, regulatory, non-sarcomeric
chr22_+_24951949 101.82 ENST00000402849.1
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr19_+_30097181 100.84 ENST00000586420.1
ENST00000221770.3
ENST00000392279.3
ENST00000590688.1
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
chrX_+_118602363 100.65 ENST00000317881.8
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr14_+_57735614 99.74 ENST00000261558.3
adaptor-related protein complex 5, mu 1 subunit
chr6_-_31510181 99.71 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr17_+_57784826 99.11 ENST00000262291.4
vacuole membrane protein 1
chr5_+_271752 98.79 ENST00000505221.1
ENST00000509581.1
ENST00000507528.1
programmed cell death 6
chr11_+_65769946 98.06 ENST00000533166.1
barrier to autointegration factor 1
chr20_+_3190006 96.52 ENST00000380113.3
ENST00000455664.2
ENST00000399838.3
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr3_-_49142504 96.42 ENST00000306125.6
ENST00000420147.2
glutaminyl-tRNA synthetase
chr19_+_50180317 95.64 ENST00000534465.1
protein arginine methyltransferase 1
chr6_-_31509714 95.53 ENST00000456662.1
ENST00000431908.1
ENST00000456976.1
ENST00000428450.1
ENST00000453105.2
ENST00000418897.1
ENST00000415382.2
ENST00000449074.2
ENST00000419020.1
ENST00000428098.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr8_-_121457332 95.52 ENST00000518918.1
mitochondrial ribosomal protein L13
chr18_+_3247779 94.72 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr14_-_71107921 94.28 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chr3_-_119396193 93.91 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17 cytochrome c oxidase copper chaperone
chr1_-_20987889 93.47 ENST00000415136.2
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr1_-_153518270 93.34 ENST00000354332.4
ENST00000368716.4
S100 calcium binding protein A4
chr19_+_35645618 92.50 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr3_-_49142178 92.01 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
glutaminyl-tRNA synthetase
chr4_-_100815525 91.64 ENST00000226522.8
ENST00000499666.2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr6_-_41909191 91.48 ENST00000512426.1
ENST00000372987.4
cyclin D3
chrX_+_21958814 91.46 ENST00000379404.1
ENST00000415881.2
spermine synthase
chr2_-_55496174 91.31 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
mitochondrial translational initiation factor 2
chr15_+_78833105 91.26 ENST00000558341.1
ENST00000559437.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr2_+_201936707 90.54 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr11_-_14541872 90.35 ENST00000419365.2
ENST00000530457.1
ENST00000532256.1
ENST00000533068.1
proteasome (prosome, macropain) subunit, alpha type, 1
chr16_-_30204987 89.93 ENST00000569282.1
ENST00000567436.1
bolA family member 2B
chr15_-_65282232 89.75 ENST00000416889.2
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr17_+_1944790 89.63 ENST00000575162.1
diphthamide biosynthesis 1
chr16_-_67969888 89.49 ENST00000574576.2
proteasome (prosome, macropain) subunit, beta type, 10
chr12_+_7079944 89.21 ENST00000261406.6
EMG1 N1-specific pseudouridine methyltransferase
chr19_-_45927622 88.84 ENST00000300853.3
ENST00000589165.1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr15_+_78833071 88.57 ENST00000559365.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr11_-_64013288 88.53 ENST00000542235.1
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_88070920 88.35 ENST00000524463.1
ENST00000227266.5
cathepsin C
chr6_-_32812420 88.21 ENST00000374881.2
proteasome (prosome, macropain) subunit, beta type, 8
chr3_+_151986709 88.09 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
muscleblind-like splicing regulator 1
chr18_+_19192228 87.84 ENST00000300413.5
ENST00000579618.1
ENST00000582475.1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr6_-_2842087 87.66 ENST00000537185.1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr19_-_10446449 87.40 ENST00000592439.1
intercellular adhesion molecule 3
chr19_+_9938562 87.15 ENST00000586895.1
ENST00000358666.3
ENST00000590068.1
ENST00000593087.1
ubiquitin-like 5
chr4_+_41937131 86.85 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
transmembrane protein 33
chr1_+_24018269 86.57 ENST00000374550.3
ribosomal protein L11
chr1_+_40723779 86.39 ENST00000372759.3
zinc metallopeptidase STE24
chr8_-_67974552 85.11 ENST00000357849.4
COP9 signalosome subunit 5
chr1_-_20987851 84.92 ENST00000464364.1
ENST00000602624.2
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr2_+_201754050 84.83 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chrX_+_100646190 84.63 ENST00000471855.1
ribosomal protein L36a
chr19_+_35645817 84.14 ENST00000423817.3
FXYD domain containing ion transport regulator 5
chr7_+_102988082 83.77 ENST00000292644.3
ENST00000544811.1
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr1_-_43638168 83.54 ENST00000431635.2
EBNA1 binding protein 2
chr16_-_12009833 83.39 ENST00000420576.2
G1 to S phase transition 1
chr20_+_388935 83.25 ENST00000382181.2
ENST00000400247.3
RanBP-type and C3HC4-type zinc finger containing 1
chr10_-_27443155 83.06 ENST00000427324.1
ENST00000326799.3
YME1-like 1 ATPase
chr2_-_55496344 83.04 ENST00000403721.1
ENST00000263629.4
mitochondrial translational initiation factor 2
chr6_+_30035307 83.04 ENST00000376765.2
ENST00000376763.1
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr11_+_65769550 82.88 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
barrier to autointegration factor 1
chr12_+_69979210 82.86 ENST00000544368.2
chaperonin containing TCP1, subunit 2 (beta)
chr12_-_112847108 82.81 ENST00000549847.1
ribosomal protein L6
chr3_+_160117087 82.56 ENST00000357388.3
structural maintenance of chromosomes 4
chr11_-_65655906 82.31 ENST00000533045.1
ENST00000338369.2
ENST00000357519.4
fibroblast growth factor (acidic) intracellular binding protein
chr15_-_65282274 82.09 ENST00000204566.2
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr15_-_101835110 81.95 ENST00000560496.1
small nuclear ribonucleoprotein polypeptide A'
chr6_-_32811771 81.65 ENST00000395339.3
ENST00000374882.3
proteasome (prosome, macropain) subunit, beta type, 8
chr3_-_133380731 81.45 ENST00000260810.5
topoisomerase (DNA) II binding protein 1
chr11_-_64013663 81.10 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_+_201754135 81.01 ENST00000409357.1
ENST00000409129.2
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr12_-_66563786 80.77 ENST00000542724.1
transmembrane BAX inhibitor motif containing 4
chr15_+_78832747 80.71 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
proteasome (prosome, macropain) subunit, alpha type, 4
chr10_+_51371390 80.47 ENST00000478381.1
ENST00000451577.2
ENST00000374098.2
ENST00000374097.2
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr5_-_140070897 80.28 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
histidyl-tRNA synthetase
chr8_-_55014336 79.86 ENST00000343231.6
lysophospholipase I
chr9_+_116037922 79.43 ENST00000374198.4
pre-mRNA processing factor 4
chr7_+_30634297 79.19 ENST00000389266.3
glycyl-tRNA synthetase
chr22_-_29949634 79.12 ENST00000397872.1
ENST00000397871.1
ENST00000440771.1
THO complex 5
chr12_-_498620 79.04 ENST00000399788.2
ENST00000382815.4
lysine (K)-specific demethylase 5A
chr17_+_73008755 78.65 ENST00000584208.1
ENST00000301585.5
immature colon carcinoma transcript 1
chr5_-_150284351 78.07 ENST00000427179.1
zinc finger protein 300
chr7_+_99006550 78.02 ENST00000222969.5
BUD31 homolog (S. cerevisiae)
chr16_-_85833160 77.99 ENST00000435200.2
ER membrane protein complex subunit 8
chr4_-_10118348 77.57 ENST00000502702.1
WD repeat domain 1
chr6_+_32811885 77.37 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr5_+_271733 76.51 ENST00000264933.4
programmed cell death 6
chr21_-_46340884 76.17 ENST00000302347.5
ENST00000517819.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr3_+_142720366 76.03 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2 snRNP-associated SURP domain containing
chr7_-_99698338 75.92 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr10_+_75504105 75.89 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24 family member C
chr15_-_64455404 75.30 ENST00000300026.3
peptidylprolyl isomerase B (cyclophilin B)
chr16_-_29465668 75.27 ENST00000569622.1
BolA-like protein 2
chr1_-_63988846 75.19 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
integrin beta 3 binding protein (beta3-endonexin)
chr6_+_30034865 74.88 ENST00000376772.3
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr4_-_120988229 74.77 ENST00000296509.6
MAD2 mitotic arrest deficient-like 1 (yeast)
chr1_+_24019099 74.44 ENST00000443624.1
ENST00000458455.1
ribosomal protein L11
chr4_-_10118573 74.23 ENST00000382452.2
ENST00000382451.2
WD repeat domain 1
chr5_+_68530668 74.10 ENST00000506563.1
cyclin-dependent kinase 7
chr7_-_54826920 73.90 ENST00000395535.3
ENST00000352861.4
Sec61 gamma subunit
chr2_+_122494676 73.79 ENST00000455432.1
translin
chr15_+_75074410 73.62 ENST00000439220.2
c-src tyrosine kinase
chr11_+_118889142 73.50 ENST00000533632.1
trafficking protein particle complex 4
chr1_-_108742957 73.33 ENST00000565488.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr1_+_32479430 73.29 ENST00000327300.7
ENST00000492989.1
KH domain containing, RNA binding, signal transduction associated 1
chr11_+_118230287 73.06 ENST00000252108.3
ENST00000431736.2
ubiquitination factor E4A
chr12_+_51632638 72.84 ENST00000549732.2
DAZ associated protein 2
chr5_-_176778523 72.61 ENST00000513877.1
ENST00000515209.1
ENST00000514458.1
ENST00000502560.1
lectin, mannose-binding 2
chr14_-_21979428 72.09 ENST00000538267.1
ENST00000298717.4
methyltransferase like 3
chr1_-_159894319 72.02 ENST00000320307.4
transgelin 2
chr7_+_44240520 71.96 ENST00000496112.1
ENST00000223369.2
YKT6 v-SNARE homolog (S. cerevisiae)
chr15_-_83736091 71.92 ENST00000261721.4
BTB (POZ) domain containing 1
chr11_-_57298187 71.89 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr19_-_10450328 71.67 ENST00000160262.5
intercellular adhesion molecule 3
chr15_+_66161802 71.49 ENST00000566233.1
ENST00000565075.1
ENST00000435304.2
RAB11A, member RAS oncogene family
chr20_-_33872518 70.49 ENST00000374436.3
eukaryotic translation initiation factor 6
chr7_-_102119342 70.38 ENST00000393794.3
ENST00000292614.5
polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr1_-_20987982 70.37 ENST00000375048.3
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr9_-_88969303 70.30 ENST00000277141.6
ENST00000375963.3
zinc finger, CCHC domain containing 6
chr7_+_2281843 70.28 ENST00000356714.1
ENST00000397049.1
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr9_-_2844058 70.07 ENST00000397885.2
KIAA0020
chr12_-_121019165 70.00 ENST00000341039.2
ENST00000357500.4
processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr2_-_230786679 70.00 ENST00000543084.1
ENST00000343290.5
ENST00000389044.4
ENST00000283943.5
thyroid hormone receptor interactor 12
chr6_+_22569784 70.00 ENST00000510882.2
hepatoma derived growth factor-like 1
chr15_+_44092784 69.92 ENST00000458412.1
huntingtin interacting protein K
chr20_-_33872548 69.76 ENST00000374443.3
eukaryotic translation initiation factor 6
chr16_-_85833109 69.72 ENST00000253457.3
ER membrane protein complex subunit 8

Network of associatons between targets according to the STRING database.

First level regulatory network of ELF2_GABPA_ELF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
92.0 276.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
91.6 274.7 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
75.4 377.2 GO:0019348 dolichol metabolic process(GO:0019348)
72.4 217.3 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
71.5 357.5 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
69.6 208.7 GO:0090149 mitochondrial membrane fission(GO:0090149)
64.8 194.5 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
63.1 252.3 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
62.5 187.4 GO:0006597 spermine biosynthetic process(GO:0006597)
61.8 247.3 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
58.9 176.6 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
58.3 233.2 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
57.0 171.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
56.1 224.6 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
55.8 167.3 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
54.3 271.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
53.5 214.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
52.4 209.7 GO:0010796 regulation of multivesicular body size(GO:0010796)
51.3 154.0 GO:1903722 regulation of centriole elongation(GO:1903722)
49.2 49.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
49.2 147.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
46.3 185.1 GO:0032218 riboflavin transport(GO:0032218)
44.4 177.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
41.3 124.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
40.3 161.0 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
39.9 159.5 GO:0006203 dGTP catabolic process(GO:0006203)
39.3 275.4 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
38.7 116.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
38.6 193.1 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
38.1 152.4 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
37.5 112.5 GO:1902822 regulation of late endosome to lysosome transport(GO:1902822)
36.8 110.4 GO:0015846 polyamine transport(GO:0015846)
36.4 109.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
36.4 109.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
36.4 218.7 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
35.8 107.4 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
35.4 212.5 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
35.2 176.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
35.2 211.0 GO:1904431 positive regulation of t-circle formation(GO:1904431)
34.8 34.8 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
34.2 102.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
33.9 339.0 GO:0051096 positive regulation of helicase activity(GO:0051096)
33.0 231.1 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
32.8 131.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
32.8 65.6 GO:0046070 dGTP metabolic process(GO:0046070)
32.8 98.4 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
32.3 129.0 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
32.2 96.7 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
32.2 96.5 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
31.8 190.8 GO:0015866 ADP transport(GO:0015866)
31.8 95.3 GO:0002084 protein depalmitoylation(GO:0002084)
31.6 63.3 GO:0002188 translation reinitiation(GO:0002188)
31.4 503.0 GO:0043248 proteasome assembly(GO:0043248)
31.0 31.0 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
30.1 120.3 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
30.0 89.9 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
29.9 239.6 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
29.7 59.4 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
29.5 118.0 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
29.5 88.4 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
29.4 88.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
29.3 205.1 GO:0016074 snoRNA metabolic process(GO:0016074)
29.1 29.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
28.9 115.6 GO:0071461 cellular response to redox state(GO:0071461)
28.8 86.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
28.6 114.3 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
28.4 85.3 GO:0042256 mature ribosome assembly(GO:0042256)
28.4 255.5 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
28.3 226.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
28.3 1386.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
28.2 84.7 GO:0070668 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
28.1 84.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
27.8 27.8 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
27.7 83.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
27.7 27.7 GO:0006513 protein monoubiquitination(GO:0006513)
27.2 27.2 GO:0036480 neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) positive regulation of oxidative stress-induced neuron death(GO:1903223) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
26.2 209.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
26.1 130.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
25.5 25.5 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
25.1 75.3 GO:1901873 regulation of post-translational protein modification(GO:1901873)
25.0 199.9 GO:0034982 mitochondrial protein processing(GO:0034982)
25.0 2321.9 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
24.9 124.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
24.7 49.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
24.5 24.5 GO:0051126 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
24.4 97.4 GO:0007144 female meiosis I(GO:0007144)
24.3 72.8 GO:0033341 regulation of collagen binding(GO:0033341)
24.3 291.1 GO:0015074 DNA integration(GO:0015074)
24.0 24.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
23.2 139.5 GO:0070475 rRNA base methylation(GO:0070475)
22.6 67.9 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
22.1 44.1 GO:0043096 purine nucleobase salvage(GO:0043096)
22.0 88.0 GO:0032790 ribosome disassembly(GO:0032790)
21.6 432.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
21.3 192.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
21.2 169.9 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
21.2 106.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
20.9 62.8 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
20.8 207.8 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
20.7 62.2 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
20.6 164.4 GO:2000210 positive regulation of anoikis(GO:2000210)
20.5 61.6 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
20.3 61.0 GO:0036089 cleavage furrow formation(GO:0036089)
20.3 81.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
20.0 140.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
19.9 59.7 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
19.8 79.0 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
19.6 78.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
19.5 58.6 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
19.5 78.1 GO:0030242 pexophagy(GO:0030242)
19.4 58.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
19.3 270.3 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
19.2 134.5 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
19.2 115.3 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
19.2 57.6 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
19.2 441.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
19.2 38.3 GO:1901656 glycoside transport(GO:1901656)
19.1 114.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
19.1 95.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
18.7 56.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
18.5 18.5 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
18.5 55.5 GO:0046294 formaldehyde catabolic process(GO:0046294)
18.5 74.0 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
18.4 36.9 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
18.3 182.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
18.3 109.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
18.1 72.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
18.0 269.8 GO:0033523 histone H2B ubiquitination(GO:0033523)
17.9 53.7 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
17.9 17.9 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
17.9 804.9 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
17.8 17.8 GO:0046102 inosine metabolic process(GO:0046102)
17.5 280.0 GO:0006295 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
17.4 261.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
17.4 52.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
17.3 138.7 GO:0006983 ER overload response(GO:0006983)
17.2 51.7 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
17.1 51.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
17.1 342.1 GO:0043101 purine-containing compound salvage(GO:0043101)
17.1 119.7 GO:0045048 protein insertion into ER membrane(GO:0045048)
17.1 51.3 GO:0006624 vacuolar protein processing(GO:0006624)
17.0 17.0 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
17.0 84.8 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
16.8 50.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
16.6 83.1 GO:0071964 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
16.5 99.2 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
16.5 66.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
16.4 131.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
16.4 81.8 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
16.3 48.9 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
16.3 260.4 GO:0060546 negative regulation of necroptotic process(GO:0060546)
16.2 16.2 GO:0006404 RNA import into nucleus(GO:0006404)
16.2 64.7 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
16.1 32.2 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
16.1 16.1 GO:0060613 fat pad development(GO:0060613)
16.1 32.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
16.0 79.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
15.9 15.9 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
15.8 79.0 GO:0048478 replication fork protection(GO:0048478)
15.8 47.3 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
15.7 47.1 GO:0097327 response to antineoplastic agent(GO:0097327)
15.7 94.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
15.6 78.2 GO:0010710 regulation of collagen catabolic process(GO:0010710)
15.6 31.2 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
15.6 1464.7 GO:0002181 cytoplasmic translation(GO:0002181)
15.6 171.4 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
15.5 665.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
15.4 61.7 GO:0016240 autophagosome docking(GO:0016240)
15.2 76.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
15.1 45.4 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
15.0 120.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
15.0 254.7 GO:1904872 regulation of telomerase RNA localization to Cajal body(GO:1904872)
14.9 104.6 GO:0006226 dUMP biosynthetic process(GO:0006226)
14.8 59.3 GO:0043335 protein unfolding(GO:0043335)
14.6 73.2 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
14.6 102.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
14.6 989.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
14.4 57.5 GO:0071492 cellular response to UV-A(GO:0071492)
14.4 71.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
14.3 86.0 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
14.3 157.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
14.2 198.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
14.1 56.4 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
13.9 41.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
13.8 41.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
13.8 41.4 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
13.7 41.2 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
13.7 27.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
13.7 218.9 GO:0000338 protein deneddylation(GO:0000338)
13.7 287.0 GO:0045948 positive regulation of translational initiation(GO:0045948)
13.7 95.7 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
13.6 40.9 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
13.6 27.2 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
13.6 68.0 GO:1904798 positive regulation of core promoter binding(GO:1904798)
13.6 68.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
13.5 40.6 GO:2000232 positive regulation of ribosome biogenesis(GO:0090070) regulation of rRNA processing(GO:2000232) positive regulation of rRNA processing(GO:2000234)
13.5 1025.1 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
13.3 119.6 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
13.2 13.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
13.1 52.3 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
13.1 65.3 GO:0018158 protein oxidation(GO:0018158)
12.9 258.8 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
12.8 115.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
12.8 51.1 GO:0042278 purine nucleoside metabolic process(GO:0042278)
12.8 38.3 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
12.7 12.7 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
12.7 12.7 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
12.6 126.1 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
12.6 37.8 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
12.6 37.8 GO:1902416 positive regulation of mRNA binding(GO:1902416)
12.6 37.8 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
12.6 37.7 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
12.6 37.7 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
12.5 50.0 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
12.5 87.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
12.4 260.3 GO:0006465 signal peptide processing(GO:0006465)
12.4 37.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
12.4 86.5 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
12.3 245.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
12.2 12.2 GO:0021997 neural plate axis specification(GO:0021997)
12.2 73.3 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
12.2 61.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
12.2 206.8 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
12.1 60.6 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085)
12.1 121.0 GO:0015939 pantothenate metabolic process(GO:0015939)
12.0 48.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
12.0 156.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
11.9 512.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
11.8 47.4 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
11.8 165.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
11.8 35.4 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
11.8 11.8 GO:0051224 negative regulation of protein transport(GO:0051224)
11.8 11.8 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
11.6 11.6 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
11.5 34.6 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
11.5 80.6 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
11.4 22.9 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
11.4 34.3 GO:0042351 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
11.4 856.4 GO:0045047 protein targeting to ER(GO:0045047)
11.4 45.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
11.3 169.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
11.2 44.9 GO:0033182 regulation of histone ubiquitination(GO:0033182)
11.2 22.4 GO:0046292 formaldehyde metabolic process(GO:0046292)
11.2 44.8 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
11.2 33.5 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
11.2 11.2 GO:0042180 cellular ketone metabolic process(GO:0042180)
11.1 66.9 GO:0007386 compartment pattern specification(GO:0007386)
11.1 156.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
11.1 77.9 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
11.1 33.3 GO:0051685 maintenance of ER location(GO:0051685)
11.1 166.2 GO:0006415 translational termination(GO:0006415)
11.0 11.0 GO:0070341 fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344) negative regulation of fat cell proliferation(GO:0070345)
10.9 21.9 GO:1904796 regulation of core promoter binding(GO:1904796)
10.9 87.6 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
10.9 32.7 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
10.9 21.8 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of pre-mRNA at the site of transcription(GO:0071033) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
10.9 43.6 GO:0006740 NADPH regeneration(GO:0006740)
10.9 32.6 GO:1901355 response to rapamycin(GO:1901355)
10.9 130.3 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
10.8 43.3 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
10.8 54.0 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
10.8 118.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
10.7 107.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
10.7 10.7 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
10.6 84.9 GO:0001887 selenium compound metabolic process(GO:0001887)
10.6 74.3 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
10.6 392.5 GO:0042407 cristae formation(GO:0042407)
10.6 21.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
10.5 168.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
10.5 84.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
10.5 21.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
10.5 42.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
10.4 125.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
10.4 51.9 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
10.4 341.9 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
10.4 10.4 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
10.4 31.1 GO:1901253 regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
10.3 51.6 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
10.3 41.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
10.3 92.5 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
10.2 726.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
10.2 61.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
10.0 30.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
10.0 20.0 GO:0001923 B-1 B cell differentiation(GO:0001923)
10.0 49.9 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
10.0 29.9 GO:0006167 AMP biosynthetic process(GO:0006167)
9.9 29.7 GO:2000254 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093) regulation of male germ cell proliferation(GO:2000254)
9.9 39.6 GO:1901804 glucosylceramide catabolic process(GO:0006680) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
9.9 19.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
9.7 29.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
9.6 19.1 GO:0003162 atrioventricular node development(GO:0003162)
9.6 38.3 GO:0090170 regulation of Golgi inheritance(GO:0090170)
9.5 38.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
9.4 217.3 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
9.4 47.2 GO:0015862 uridine transport(GO:0015862)
9.4 28.2 GO:0071421 manganese ion transmembrane transport(GO:0071421)
9.3 37.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
9.3 27.8 GO:0061198 fungiform papilla formation(GO:0061198)
9.2 9.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
9.2 73.6 GO:0035268 protein mannosylation(GO:0035268)
9.1 36.4 GO:0043366 beta selection(GO:0043366)
9.1 353.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
9.1 18.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
9.0 27.0 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
9.0 9.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
9.0 9.0 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
9.0 62.9 GO:0072718 response to cisplatin(GO:0072718)
8.9 17.9 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
8.9 26.6 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
8.9 35.5 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
8.9 79.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
8.8 79.3 GO:1902969 mitotic DNA replication(GO:1902969)
8.8 8.8 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212)
8.8 35.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
8.8 52.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
8.8 87.7 GO:0071044 histone mRNA catabolic process(GO:0071044)
8.8 35.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
8.7 34.9 GO:0030047 actin modification(GO:0030047)
8.7 43.3 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
8.6 43.2 GO:0033753 ribosomal subunit export from nucleus(GO:0000054) ribosomal large subunit export from nucleus(GO:0000055) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
8.6 664.5 GO:0006413 translational initiation(GO:0006413)
8.6 17.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
8.6 25.7 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
8.5 8.5 GO:2000196 positive regulation of female gonad development(GO:2000196)
8.5 42.6 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
8.5 17.0 GO:0072321 chaperone-mediated protein transport(GO:0072321)
8.5 8.5 GO:0061010 gall bladder development(GO:0061010)
8.5 110.2 GO:0016180 snRNA processing(GO:0016180)
8.5 33.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
8.4 25.3 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
8.4 168.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
8.4 42.1 GO:2000035 regulation of stem cell division(GO:2000035)
8.4 41.9 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
8.4 58.5 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
8.3 16.7 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
8.3 8.3 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
8.3 24.9 GO:0009304 tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
8.3 132.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
8.3 49.6 GO:0002638 negative regulation of immunoglobulin production(GO:0002638)
8.2 8.2 GO:0019087 transformation of host cell by virus(GO:0019087)
8.2 49.3 GO:0051013 microtubule severing(GO:0051013)
8.2 106.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
8.1 32.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
8.1 560.1 GO:0045454 cell redox homeostasis(GO:0045454)
8.1 145.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
8.0 32.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
8.0 24.1 GO:0019417 sulfur oxidation(GO:0019417)
8.0 48.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
8.0 40.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
8.0 104.0 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
8.0 32.0 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
8.0 318.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
7.9 7.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
7.8 39.2 GO:0044351 macropinocytosis(GO:0044351)
7.8 23.3 GO:0071789 spindle pole body duplication(GO:0030474) nuclear pore distribution(GO:0031081) spindle pole body organization(GO:0051300) nuclear pore localization(GO:0051664) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
7.7 7.7 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
7.7 69.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
7.7 23.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
7.6 38.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
7.6 76.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
7.6 68.3 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
7.5 15.1 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
7.5 30.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
7.5 15.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
7.5 22.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
7.4 22.3 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
7.4 119.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
7.4 81.5 GO:0060263 regulation of respiratory burst(GO:0060263)
7.4 44.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
7.3 29.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
7.3 43.9 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
7.3 21.9 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
7.3 21.9 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
7.3 538.3 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
7.3 43.5 GO:0090161 Golgi ribbon formation(GO:0090161)
7.2 64.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
7.2 143.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
7.2 21.5 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
7.1 35.7 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
7.1 135.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
7.1 42.7 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
7.1 7.1 GO:0070671 response to interleukin-12(GO:0070671)
7.1 35.3 GO:1902903 late endosomal microautophagy(GO:0061738) regulation of fibril organization(GO:1902903)
7.0 14.0 GO:0014900 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
7.0 27.8 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
6.9 48.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
6.9 41.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
6.8 20.5 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
6.8 20.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
6.8 6.8 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
6.8 339.7 GO:0045071 negative regulation of viral genome replication(GO:0045071)
6.8 33.9 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
6.8 74.3 GO:0051601 exocyst localization(GO:0051601)
6.7 20.2 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
6.7 46.7 GO:0038203 TORC2 signaling(GO:0038203)
6.6 33.0 GO:0009838 abscission(GO:0009838)
6.6 52.8 GO:0051014 actin filament severing(GO:0051014)
6.6 26.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
6.6 6.6 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
6.6 6.6 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
6.5 183.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
6.5 58.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
6.5 52.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
6.5 6.5 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
6.4 12.9 GO:0045091 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
6.4 6.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
6.4 38.6 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
6.3 31.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
6.3 69.6 GO:0018345 protein palmitoylation(GO:0018345)
6.3 44.3 GO:0046618 drug export(GO:0046618)
6.3 18.8 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
6.3 50.0 GO:0032506 cytokinetic process(GO:0032506)
6.2 37.5 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
6.2 31.0 GO:0042631 cellular response to water deprivation(GO:0042631)
6.2 37.2 GO:0046898 response to cycloheximide(GO:0046898)
6.2 49.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
6.2 12.4 GO:1902570 protein localization to nucleolus(GO:1902570)
6.2 6.2 GO:0040031 snRNA modification(GO:0040031)
6.2 30.8 GO:0090204 protein localization to nuclear pore(GO:0090204)
6.2 12.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
6.1 147.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
6.1 12.2 GO:0090166 Golgi disassembly(GO:0090166)
6.1 12.2 GO:1903333 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
6.1 67.0 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
6.0 6.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
6.0 108.7 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
6.0 11.9 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
6.0 59.6 GO:0045116 protein neddylation(GO:0045116)
5.9 41.5 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
5.9 473.3 GO:0070527 platelet aggregation(GO:0070527)
5.9 76.6 GO:0097320 membrane tubulation(GO:0097320)
5.9 58.9 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
5.9 23.5 GO:0030259 lipid glycosylation(GO:0030259)
5.9 135.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
5.8 52.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
5.8 11.6 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
5.8 121.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
5.7 22.9 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
5.7 125.9 GO:0006825 copper ion transport(GO:0006825)
5.7 22.9 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
5.7 392.9 GO:0043488 regulation of mRNA stability(GO:0043488)
5.7 39.8 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
5.7 39.7 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
5.7 22.6 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
5.6 11.3 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
5.6 1580.8 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
5.6 123.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
5.6 72.4 GO:0050766 positive regulation of phagocytosis(GO:0050766)
5.5 16.6 GO:0016139 glycoside catabolic process(GO:0016139)
5.5 16.6 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
5.5 11.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
5.5 5.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
5.5 11.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
5.4 16.3 GO:0051684 maintenance of Golgi location(GO:0051684)
5.4 10.7 GO:0009886 post-embryonic morphogenesis(GO:0009886) post-embryonic organ morphogenesis(GO:0048563)
5.4 32.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
5.3 5.3 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
5.3 90.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
5.3 26.6 GO:0009303 rRNA transcription(GO:0009303)
5.3 16.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
5.3 15.9 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
5.3 52.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
5.3 47.4 GO:0018344 protein geranylgeranylation(GO:0018344)
5.3 231.9 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
5.3 21.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
5.3 31.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
5.3 15.8 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
5.2 47.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
5.2 15.6 GO:0032497 detection of lipopolysaccharide(GO:0032497)
5.1 5.1 GO:1902566 regulation of eosinophil activation(GO:1902566)
5.1 154.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
5.1 35.8 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
5.0 5.0 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
5.0 5.0 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
5.0 25.1 GO:1904424 regulation of GTP binding(GO:1904424)
5.0 25.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
5.0 9.9 GO:0015920 lipopolysaccharide transport(GO:0015920)
4.9 14.8 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
4.9 9.9 GO:0034214 protein hexamerization(GO:0034214)
4.9 9.8 GO:1903978 regulation of microglial cell activation(GO:1903978)
4.9 9.8 GO:0009147 pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
4.8 9.7 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
4.8 29.0 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
4.8 38.6 GO:0051382 kinetochore assembly(GO:0051382)
4.8 19.3 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
4.8 230.9 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
4.8 14.4 GO:1902992 negative regulation of amyloid precursor protein catabolic process(GO:1902992)
4.8 19.2 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
4.7 4.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
4.7 47.4 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
4.7 47.2 GO:1900086 regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
4.7 18.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
4.7 56.2 GO:0007172 signal complex assembly(GO:0007172)
4.7 379.1 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
4.7 51.4 GO:0019388 galactose catabolic process(GO:0019388)
4.6 4.6 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
4.6 9.2 GO:1902680 positive regulation of RNA biosynthetic process(GO:1902680)
4.6 9.2 GO:0044275 cellular carbohydrate catabolic process(GO:0044275)
4.6 41.2 GO:1903027 regulation of opsonization(GO:1903027)
4.6 45.6 GO:0045793 positive regulation of cell size(GO:0045793)
4.6 31.9 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
4.5 13.6 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
4.5 13.6 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
4.5 45.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
4.5 44.9 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
4.4 31.1 GO:0000733 DNA strand renaturation(GO:0000733)
4.4 13.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
4.4 30.9 GO:0051599 response to hydrostatic pressure(GO:0051599)
4.4 79.2 GO:0035641 locomotory exploration behavior(GO:0035641)
4.3 17.3 GO:1903224 regulation of endodermal cell differentiation(GO:1903224) negative regulation of gastrulation(GO:2000542)
4.3 25.9 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
4.3 30.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
4.3 8.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
4.3 25.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
4.3 68.4 GO:0007220 Notch receptor processing(GO:0007220)
4.3 8.5 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
4.3 17.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
4.2 46.7 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
4.2 25.4 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
4.2 42.3 GO:0060056 mammary gland involution(GO:0060056)
4.2 134.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
4.2 25.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
4.2 12.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
4.2 4.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
4.1 8.3 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
4.1 20.7 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
4.1 16.6 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
4.1 49.6 GO:0016578 histone deubiquitination(GO:0016578)
4.1 20.6 GO:1904693 midbrain morphogenesis(GO:1904693)
4.1 8.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
4.1 24.5 GO:0045064 T-helper 2 cell differentiation(GO:0045064)
4.1 8.2 GO:0061724 lipophagy(GO:0061724) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
4.1 24.4 GO:0043418 homocysteine catabolic process(GO:0043418)
4.1 32.6 GO:0070200 establishment of protein localization to telomere(GO:0070200)
4.1 8.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
4.1 4.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
4.1 48.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
4.1 20.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
4.0 16.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
4.0 12.1 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
4.0 72.4 GO:0051290 protein heterotetramerization(GO:0051290)
4.0 28.1 GO:0008216 spermidine metabolic process(GO:0008216)
4.0 12.0 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
4.0 71.9 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
4.0 23.9 GO:0051974 negative regulation of telomerase activity(GO:0051974)
4.0 19.9 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
4.0 203.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
4.0 4.0 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
4.0 23.9 GO:0060011 Sertoli cell proliferation(GO:0060011)
4.0 39.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
4.0 7.9 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
3.9 15.8 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
3.9 98.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
3.9 15.7 GO:0039530 MDA-5 signaling pathway(GO:0039530)
3.9 11.8 GO:0090160 Golgi to lysosome transport(GO:0090160)
3.9 62.8 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
3.9 7.8 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
3.9 23.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
3.9 7.8 GO:0008356 asymmetric cell division(GO:0008356)
3.9 27.2 GO:0031648 protein destabilization(GO:0031648)
3.9 34.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
3.9 19.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
3.9 19.3 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
3.8 53.7 GO:0035855 megakaryocyte development(GO:0035855)
3.8 194.9 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
3.8 3.8 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
3.8 117.7 GO:0090383 phagosome acidification(GO:0090383)
3.8 11.3 GO:0002418 immune response to tumor cell(GO:0002418)
3.8 56.6 GO:0031639 plasminogen activation(GO:0031639)
3.8 18.9 GO:1903232 melanosome assembly(GO:1903232)
3.8 41.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
3.8 11.3 GO:0030099 myeloid cell differentiation(GO:0030099)
3.8 60.1 GO:0098969 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
3.7 63.4 GO:0000002 mitochondrial genome maintenance(GO:0000002)
3.7 14.9 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
3.7 7.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
3.7 26.0 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
3.7 37.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
3.7 7.4 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
3.7 18.5 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
3.7 25.8 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
3.7 158.2 GO:0043171 peptide catabolic process(GO:0043171)
3.7 25.7 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
3.7 58.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
3.7 11.0 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
3.7 25.6 GO:0032486 Rap protein signal transduction(GO:0032486)
3.6 90.7 GO:0009235 cobalamin metabolic process(GO:0009235)
3.6 18.0 GO:0000722 telomere maintenance via recombination(GO:0000722)
3.6 10.8 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
3.6 14.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
3.6 103.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
3.5 343.3 GO:0008380 RNA splicing(GO:0008380)
3.5 3.5 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
3.5 28.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
3.5 17.5 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
3.5 55.6 GO:0006337 nucleosome disassembly(GO:0006337)
3.5 24.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
3.5 24.3 GO:0000012 single strand break repair(GO:0000012)
3.4 6.9 GO:0002384 hepatic immune response(GO:0002384)
3.4 10.3 GO:0035624 receptor transactivation(GO:0035624)
3.4 27.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
3.4 3.4 GO:0051595 response to methylglyoxal(GO:0051595)
3.4 6.8 GO:0044065 regulation of respiratory system process(GO:0044065)
3.4 95.4 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
3.4 6.8 GO:0002347 response to tumor cell(GO:0002347)
3.4 27.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
3.4 10.1 GO:0002880 microglial cell activation involved in immune response(GO:0002282) chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880) negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
3.4 26.9 GO:0071404 cellular response to low-density lipoprotein particle stimulus(GO:0071404)
3.4 43.7 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
3.4 20.2 GO:0031935 regulation of chromatin silencing(GO:0031935)
3.4 70.4 GO:0006119 oxidative phosphorylation(GO:0006119)
3.4 23.5 GO:0071223 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
3.3 26.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
3.3 9.9 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
3.3 16.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
3.3 32.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
3.3 13.1 GO:0060155 platelet dense granule organization(GO:0060155)
3.3 71.6 GO:0006903 vesicle targeting(GO:0006903)
3.2 6.5 GO:0043382 regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382)
3.2 155.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
3.2 19.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
3.2 9.7 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
3.2 3.2 GO:0010039 response to iron ion(GO:0010039)
3.2 6.4 GO:0090270 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
3.2 69.6 GO:0043968 histone H2A acetylation(GO:0043968)
3.2 19.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
3.1 15.7 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
3.1 25.2 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
3.1 12.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
3.1 3.1 GO:0031291 Ran protein signal transduction(GO:0031291)
3.1 21.7 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
3.1 12.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
3.1 12.4 GO:0006183 GTP biosynthetic process(GO:0006183)
3.1 21.7 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
3.1 9.3 GO:0051661 maintenance of centrosome location(GO:0051661)
3.1 3.1 GO:0019346 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
3.1 6.2 GO:0021764 amygdala development(GO:0021764)
3.1 9.2 GO:0086054 pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
3.1 52.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
3.1 12.3 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
3.0 12.2 GO:0071352 interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352)
3.0 15.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
3.0 24.3 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
3.0 33.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
3.0 39.1 GO:0060632 regulation of microtubule-based movement(GO:0060632)
3.0 6.0 GO:0060434 bronchus morphogenesis(GO:0060434)
3.0 23.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
3.0 20.8 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
3.0 8.9 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
3.0 26.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
2.9 8.8 GO:0090343 positive regulation of cell aging(GO:0090343)
2.9 8.8 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
2.9 2.9 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
2.9 14.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
2.9 2.9 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
2.9 144.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
2.9 2.9 GO:0048709 oligodendrocyte differentiation(GO:0048709)
2.8 2.8 GO:0051182 coenzyme transport(GO:0051182)
2.8 8.5 GO:0046521 sphingoid catabolic process(GO:0046521)
2.8 22.5 GO:0035562 negative regulation of chromatin binding(GO:0035562)
2.8 14.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
2.8 5.6 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
2.8 39.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.8 22.3 GO:0015816 glycine transport(GO:0015816)
2.8 27.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
2.8 5.5 GO:0016095 polyprenol catabolic process(GO:0016095)
2.8 16.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
2.7 13.7 GO:1903599 positive regulation of mitophagy(GO:1903599)
2.7 5.5 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
2.7 16.4 GO:1902591 single-organism membrane budding(GO:1902591)
2.7 46.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
2.7 24.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
2.7 2.7 GO:0035627 ceramide transport(GO:0035627)
2.7 10.7 GO:0043555 regulation of translation in response to stress(GO:0043555)
2.7 5.3 GO:1901856 negative regulation of cellular respiration(GO:1901856)
2.6 7.8 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
2.6 15.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
2.6 10.3 GO:0015793 glycerol transport(GO:0015793)
2.6 25.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
2.5 43.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
2.5 22.8 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
2.5 5.0 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
2.5 17.6 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
2.5 25.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
2.5 39.9 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
2.5 37.1 GO:0008053 mitochondrial fusion(GO:0008053)
2.5 9.9 GO:0002934 desmosome organization(GO:0002934)
2.5 2.5 GO:0043985 histone H4-R3 methylation(GO:0043985)
2.5 12.3 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
2.4 36.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
2.4 24.4 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
2.4 16.9 GO:1902031 regulation of NADP metabolic process(GO:1902031)
2.4 12.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
2.4 19.1 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
2.4 2.4 GO:0051683 establishment of Golgi localization(GO:0051683)
2.4 9.5 GO:0034205 beta-amyloid formation(GO:0034205)
2.4 4.7 GO:0072757 cellular response to camptothecin(GO:0072757)
2.4 7.1 GO:0006642 triglyceride mobilization(GO:0006642)
2.4 9.5 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
2.4 26.0 GO:0032781 positive regulation of ATPase activity(GO:0032781)
2.4 21.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
2.3 4.7 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
2.3 35.2 GO:0032060 bleb assembly(GO:0032060)
2.3 4.7 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
2.3 9.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
2.3 23.3 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
2.3 9.3 GO:0071763 nuclear membrane organization(GO:0071763)
2.3 374.5 GO:0006457 protein folding(GO:0006457)
2.3 4.6 GO:0007266 Rho protein signal transduction(GO:0007266)
2.3 31.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
2.3 9.0 GO:0007613 memory(GO:0007613)
2.3 9.0 GO:0014894 response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
2.2 20.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
2.2 2.2 GO:2000618 regulation of histone H4-K16 acetylation(GO:2000618)
2.2 17.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
2.2 8.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
2.2 33.0 GO:0048853 forebrain morphogenesis(GO:0048853)
2.2 52.7 GO:0005980 glycogen catabolic process(GO:0005980)
2.2 4.4 GO:0060352 cell adhesion molecule production(GO:0060352)
2.2 6.5 GO:0032252 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252)
2.2 8.7 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
2.2 15.1 GO:0030091 protein repair(GO:0030091)
2.2 64.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
2.2 21.5 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
2.1 10.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
2.1 10.7 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
2.1 6.4 GO:0010649 regulation of cell communication by electrical coupling(GO:0010649)
2.1 10.5 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
2.1 2.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
2.1 6.3 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
2.1 12.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
2.1 24.7 GO:0016071 mRNA metabolic process(GO:0016071)
2.0 6.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
2.0 10.2 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
2.0 40.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
2.0 2.0 GO:0048382 mesendoderm development(GO:0048382)
2.0 10.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
2.0 2.0 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
2.0 30.0 GO:0007019 microtubule depolymerization(GO:0007019)
2.0 8.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
2.0 2.0 GO:0032647 regulation of interferon-alpha production(GO:0032647)
2.0 9.9 GO:0030263 apoptotic chromosome condensation(GO:0030263)
2.0 277.1 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043122)
2.0 11.8 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
2.0 19.5 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
2.0 50.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
1.9 19.3 GO:0010452 histone H3-K36 methylation(GO:0010452)
1.9 13.5 GO:0006105 succinate metabolic process(GO:0006105)
1.9 55.2 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
1.9 15.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.9 13.2 GO:0051299 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
1.9 30.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
1.9 5.6 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
1.9 41.1 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
1.9 7.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
1.9 3.7 GO:0051451 myoblast migration(GO:0051451)
1.9 9.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
1.9 14.8 GO:0033028 myeloid cell apoptotic process(GO:0033028)
1.8 51.7 GO:0006611 protein export from nucleus(GO:0006611)
1.8 5.5 GO:0090031 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) positive regulation of steroid hormone biosynthetic process(GO:0090031)
1.8 3.6 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148) phosphatidylglycerol metabolic process(GO:0046471)
1.8 1.8 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
1.8 42.7 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.8 10.7 GO:0061038 uterus morphogenesis(GO:0061038)
1.8 24.8 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
1.8 39.0 GO:0017145 stem cell division(GO:0017145)
1.8 280.5 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
1.8 17.6 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.7 1.7 GO:0048293 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293) positive regulation of isotype switching to IgE isotypes(GO:0048295)
1.7 8.5 GO:0002335 mature B cell differentiation(GO:0002335)
1.7 8.5 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
1.7 28.4 GO:0032480 negative regulation of type I interferon production(GO:0032480)
1.7 20.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
1.7 5.0 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.7 5.0 GO:0061635 regulation of protein complex stability(GO:0061635)
1.7 3.3 GO:0001302 replicative cell aging(GO:0001302)
1.6 9.8 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.6 18.0 GO:0097186 amelogenesis(GO:0097186)
1.6 19.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
1.6 24.2 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
1.6 11.2 GO:0007379 segment specification(GO:0007379)
1.6 8.0 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
1.6 11.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
1.6 23.8 GO:0044804 nucleophagy(GO:0044804)
1.6 15.9 GO:0003094 glomerular filtration(GO:0003094)
1.6 6.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.6 10.9 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.6 1.6 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
1.5 21.7 GO:0007265 Ras protein signal transduction(GO:0007265)
1.5 13.8 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
1.5 6.1 GO:0040016 embryonic cleavage(GO:0040016)
1.5 12.2 GO:0070995 NADPH oxidation(GO:0070995)
1.5 34.9 GO:0006270 DNA replication initiation(GO:0006270)
1.5 105.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
1.5 25.7 GO:1901880 negative regulation of protein depolymerization(GO:1901880)
1.5 108.8 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
1.5 23.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
1.5 8.9 GO:0033151 V(D)J recombination(GO:0033151)
1.5 11.9 GO:0039529 RIG-I signaling pathway(GO:0039529)
1.5 7.4 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
1.5 135.2 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
1.5 7.3 GO:0001880 Mullerian duct regression(GO:0001880)
1.5 5.9 GO:0046836 glycolipid transport(GO:0046836)
1.5 16.1 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
1.5 448.7 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
1.4 5.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
1.4 2.9 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
1.4 44.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
1.4 2.9 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.4 8.5 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
1.4 11.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.4 8.5 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
1.4 11.2 GO:0061718 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
1.4 8.3 GO:0007018 microtubule-based movement(GO:0007018)
1.4 4.1 GO:0044344 cellular response to fibroblast growth factor stimulus(GO:0044344)
1.4 1.4 GO:0051030 snRNA export from nucleus(GO:0006408) snRNA transport(GO:0051030)
1.4 31.5 GO:0043966 histone H3 acetylation(GO:0043966)
1.4 1.4 GO:0010941 regulation of cell death(GO:0010941)
1.4 27.2 GO:0034508 centromere complex assembly(GO:0034508)
1.4 9.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.4 1.4 GO:1903201 regulation of oxidative stress-induced cell death(GO:1903201)
1.4 9.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
1.3 6.7 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
1.3 8.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
1.3 4.0 GO:0006591 ornithine metabolic process(GO:0006591)
1.3 30.6 GO:0006487 protein N-linked glycosylation(GO:0006487)
1.3 2.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
1.3 48.0 GO:0051289 protein homotetramerization(GO:0051289)
1.3 9.0 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
1.3 14.0 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566)
1.3 1.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
1.3 3.8 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
1.3 1.3 GO:0060462 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
1.2 11.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
1.2 3.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
1.2 57.9 GO:0006338 chromatin remodeling(GO:0006338)
1.2 2.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.2 7.2 GO:0048311 mitochondrion distribution(GO:0048311)
1.2 4.8 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286) positive regulation of caveolin-mediated endocytosis(GO:2001288)
1.2 11.9 GO:0007096 regulation of exit from mitosis(GO:0007096)
1.2 4.6 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
1.2 6.9 GO:0000212 meiotic spindle organization(GO:0000212)
1.2 5.8 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
1.2 1.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
1.1 1.1 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
1.1 2.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
1.1 11.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
1.1 2.2 GO:0031507 heterochromatin assembly(GO:0031507)
1.1 13.2 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
1.1 4.4 GO:0033131 regulation of glucokinase activity(GO:0033131) negative regulation of glucokinase activity(GO:0033132) regulation of hexokinase activity(GO:1903299) negative regulation of hexokinase activity(GO:1903300)
1.1 2.2 GO:0006828 manganese ion transport(GO:0006828)
1.1 16.4 GO:0006622 protein targeting to lysosome(GO:0006622)
1.1 21.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
1.1 3.3 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
1.1 31.4 GO:0031581 hemidesmosome assembly(GO:0031581)
1.1 1.1 GO:0010464 mesenchymal cell proliferation(GO:0010463) regulation of mesenchymal cell proliferation(GO:0010464)
1.1 4.3 GO:0003409 optic cup structural organization(GO:0003409)
1.1 3.2 GO:0097264 self proteolysis(GO:0097264)
1.1 2.1 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
1.1 1.1 GO:0016191 synaptic vesicle uncoating(GO:0016191) vesicle uncoating(GO:0072319)
1.0 2.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.0 6.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
1.0 11.2 GO:0050684 regulation of mRNA processing(GO:0050684)
1.0 1.0 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
1.0 3.9 GO:0009144 purine nucleoside triphosphate metabolic process(GO:0009144)
1.0 13.8 GO:0035065 regulation of histone acetylation(GO:0035065)
1.0 5.9 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
1.0 2.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.0 114.5 GO:0008360 regulation of cell shape(GO:0008360)
1.0 75.9 GO:0034728 nucleosome organization(GO:0034728)
1.0 5.8 GO:0035897 proteolysis in other organism(GO:0035897)
1.0 3.9 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
1.0 2.9 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
1.0 65.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.9 28.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.9 36.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.9 9.4 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.9 2.8 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.9 3.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.9 2.7 GO:0003341 cilium movement(GO:0003341)
0.9 9.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.9 15.2 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.9 1.8 GO:0060242 contact inhibition(GO:0060242)
0.9 2.6 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.9 8.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.9 2.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.9 8.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.9 1.7 GO:0035995 detection of muscle stretch(GO:0035995)
0.8 4.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.8 6.6 GO:0018065 protein-cofactor linkage(GO:0018065)
0.8 3.3 GO:0030728 ovulation(GO:0030728)
0.8 1.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.8 1.6 GO:0048477 oogenesis(GO:0048477)
0.8 1.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.8 4.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.8 0.8 GO:0097205 renal filtration(GO:0097205)
0.8 8.7 GO:0017085 response to insecticide(GO:0017085)
0.8 18.9 GO:0015893 drug transport(GO:0015893)
0.8 3.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075) endochondral bone morphogenesis(GO:0060350)
0.8 4.6 GO:0042100 B cell proliferation(GO:0042100)
0.8 3.1 GO:0060017 parathyroid gland development(GO:0060017)
0.8 17.4 GO:1903578 regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.7 5.1 GO:0009650 UV protection(GO:0009650)
0.7 2.9 GO:0035411 catenin import into nucleus(GO:0035411)
0.7 2.1 GO:1903054 negative regulation of extracellular matrix assembly(GO:1901202) negative regulation of extracellular matrix organization(GO:1903054)
0.7 2.1 GO:0046958 nonassociative learning(GO:0046958)
0.7 0.7 GO:0009635 response to herbicide(GO:0009635)
0.7 2.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.7 2.8 GO:0048014 Tie signaling pathway(GO:0048014) negative regulation of positive chemotaxis(GO:0050928)
0.7 0.7 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.7 9.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.7 3.3 GO:0032418 lysosome localization(GO:0032418)
0.7 5.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.7 3.3 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.7 6.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.7 2.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.6 4.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.6 1.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.6 14.6 GO:0006582 melanin metabolic process(GO:0006582)
0.6 1.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.6 3.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.6 5.5 GO:0033227 dsRNA transport(GO:0033227)
0.6 11.6 GO:0006099 tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101)
0.6 3.0 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.6 1.2 GO:0002577 regulation of antigen processing and presentation(GO:0002577)
0.6 0.6 GO:0034138 toll-like receptor 3 signaling pathway(GO:0034138)
0.6 1.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.6 5.8 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.6 2.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.6 2.9 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.6 1.1 GO:0031268 pseudopodium organization(GO:0031268)
0.6 3.4 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.6 3.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.6 1.7 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.5 1.1 GO:0003289 septum secundum development(GO:0003285) atrial septum primum morphogenesis(GO:0003289) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.5 0.5 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.5 5.4 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.5 1.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.5 1.1 GO:0090344 negative regulation of cell aging(GO:0090344)
0.5 5.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.5 3.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.5 2.6 GO:0046785 microtubule polymerization(GO:0046785)
0.5 2.6 GO:0090032 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of hormone biosynthetic process(GO:0032353) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.5 1.5 GO:0032310 prostaglandin secretion(GO:0032310)
0.5 7.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 8.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.5 4.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.5 31.4 GO:0002576 platelet degranulation(GO:0002576)
0.5 5.0 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.4 4.5 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.4 3.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.4 12.7 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.4 7.4 GO:0006308 DNA catabolic process(GO:0006308)
0.4 2.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.4 1.7 GO:0072350 tricarboxylic acid metabolic process(GO:0072350)
0.4 13.7 GO:0007030 Golgi organization(GO:0007030)
0.4 0.9 GO:0071109 superior temporal gyrus development(GO:0071109)
0.4 1.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.4 0.4 GO:0010744 positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.4 1.7 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.4 0.4 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.4 0.8 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine catabolic process(GO:0006550)
0.4 1.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.4 1.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4 0.8 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.4 2.2 GO:0070875 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.4 1.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.4 0.4 GO:1900133 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.4 1.1 GO:0010455 positive regulation of cell fate commitment(GO:0010455)
0.4 1.4 GO:0061146 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146)
0.4 1.1 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.3 0.7 GO:0043038 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.3 0.7 GO:0015791 polyol transport(GO:0015791)
0.3 2.9 GO:0016925 protein sumoylation(GO:0016925)
0.3 1.3 GO:0051283 sequestering of calcium ion(GO:0051208) release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.3 4.0 GO:0030865 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.3 2.1 GO:0051026 chiasma assembly(GO:0051026)
0.3 0.3 GO:0002251 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.3 0.6 GO:0035994 response to muscle stretch(GO:0035994)
0.3 2.0 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.3 0.3 GO:0014823 response to activity(GO:0014823)
0.3 2.0 GO:0061430 bone trabecula morphogenesis(GO:0061430)
0.3 3.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 0.5 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 4.7 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.2 0.7 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 6.7 GO:0031100 organ regeneration(GO:0031100)
0.2 1.0 GO:0042940 D-amino acid transport(GO:0042940)
0.2 2.2 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.2 0.2 GO:0046683 response to organophosphorus(GO:0046683)
0.2 0.7 GO:0033194 response to hydroperoxide(GO:0033194)
0.2 0.9 GO:1903901 negative regulation of viral life cycle(GO:1903901)
0.2 0.9 GO:0048706 embryonic skeletal system development(GO:0048706)
0.2 1.8 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.2 0.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 1.5 GO:0046697 decidualization(GO:0046697)
0.2 0.6 GO:0021564 vagus nerve development(GO:0021564)
0.2 8.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2 2.0 GO:0019079 viral genome replication(GO:0019079)
0.2 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 0.2 GO:0090382 phagosome maturation(GO:0090382)
0.2 0.9 GO:1902946 protein localization to early endosome(GO:1902946)
0.2 1.3 GO:1901186 positive regulation of ERBB signaling pathway(GO:1901186)
0.2 0.4 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.2 0.5 GO:0007512 adult heart development(GO:0007512)
0.2 3.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 0.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 1.0 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 0.7 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 2.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 0.7 GO:1903831 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2 2.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.8 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.1 0.1 GO:0071609 chemokine (C-C motif) ligand 5 production(GO:0071609)
0.1 0.4 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.5 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 1.2 GO:0006833 water transport(GO:0006833)
0.1 0.7 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.2 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.1 0.9 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.7 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 0.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1 0.9 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 1.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.4 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 1.0 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.6 GO:0010608 posttranscriptional regulation of gene expression(GO:0010608)
0.1 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.2 GO:0046137 negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.0 GO:0001541 ovarian follicle development(GO:0001541)
0.1 0.2 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.5 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.1 GO:0042182 ketone catabolic process(GO:0042182)
0.0 0.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.5 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.0 0.2 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
129.7 389.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
87.2 784.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
76.3 610.8 GO:0034715 pICln-Sm protein complex(GO:0034715)
64.9 649.4 GO:0034709 methylosome(GO:0034709)
58.0 696.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
57.0 455.6 GO:1990111 spermatoproteasome complex(GO:1990111)
51.0 306.2 GO:1902560 GMP reductase complex(GO:1902560)
48.3 193.0 GO:0070985 TFIIK complex(GO:0070985)
46.6 279.5 GO:0071817 MMXD complex(GO:0071817)
46.5 186.2 GO:0071001 U4/U6 snRNP(GO:0071001)
46.0 230.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
44.9 224.6 GO:0042643 actomyosin, actin portion(GO:0042643)
40.9 122.6 GO:0071159 NF-kappaB complex(GO:0071159)
39.5 118.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
38.8 465.2 GO:0031595 nuclear proteasome complex(GO:0031595)
38.7 116.0 GO:0018444 translation release factor complex(GO:0018444)
38.5 269.3 GO:0005787 signal peptidase complex(GO:0005787)
38.2 152.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
38.1 304.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
37.1 111.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
36.6 219.4 GO:0005688 U6 snRNP(GO:0005688)
35.9 35.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
35.4 35.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
34.4 171.8 GO:0071986 Ragulator complex(GO:0071986)
34.0 170.0 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
33.8 101.4 GO:0034455 t-UTP complex(GO:0034455)
33.7 674.5 GO:0005838 proteasome regulatory particle(GO:0005838)
33.3 233.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
33.1 298.2 GO:0072546 ER membrane protein complex(GO:0072546)
32.2 610.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
30.8 215.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
29.5 177.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
28.8 288.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
27.7 857.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
27.2 81.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
27.1 324.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
27.0 405.7 GO:0005686 U2 snRNP(GO:0005686)
26.6 133.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
25.8 129.2 GO:0032021 NELF complex(GO:0032021)
25.8 541.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
25.8 128.9 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
25.6 102.6 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
25.3 151.8 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
24.9 323.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
24.6 73.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)
24.2 72.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
24.0 72.0 GO:0097441 basilar dendrite(GO:0097441)
24.0 24.0 GO:0005687 U4 snRNP(GO:0005687)
23.6 236.5 GO:0000796 condensin complex(GO:0000796)
23.3 163.4 GO:0005663 DNA replication factor C complex(GO:0005663)
23.0 69.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
23.0 368.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
22.8 113.8 GO:0071797 LUBAC complex(GO:0071797)
22.4 111.9 GO:0097149 centralspindlin complex(GO:0097149)
22.0 65.9 GO:0035370 UBC13-UEV1A complex(GO:0035370)
21.9 87.7 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
21.5 150.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
21.4 64.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
21.3 127.8 GO:0008537 proteasome activator complex(GO:0008537)
21.1 190.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
20.7 145.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
20.3 81.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
20.1 240.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
19.2 307.6 GO:0031080 nuclear pore outer ring(GO:0031080)
18.8 188.1 GO:0097255 R2TP complex(GO:0097255)
18.4 92.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
18.3 238.0 GO:0042555 MCM complex(GO:0042555)
18.3 54.8 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
17.9 107.5 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
17.9 393.9 GO:0030127 COPII vesicle coat(GO:0030127)
17.2 310.4 GO:0097342 ripoptosome(GO:0097342)
17.1 51.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
17.1 153.6 GO:0000439 core TFIIH complex(GO:0000439)
17.0 119.1 GO:0016272 prefoldin complex(GO:0016272)
16.9 1813.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
16.8 151.2 GO:0030126 COPI vesicle coat(GO:0030126)
16.6 298.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
16.6 215.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
16.0 160.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
15.9 63.7 GO:0005846 nuclear cap binding complex(GO:0005846)
15.9 79.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
15.8 31.6 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
15.7 266.9 GO:0030686 90S preribosome(GO:0030686)
15.5 293.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
15.4 230.9 GO:0030684 preribosome(GO:0030684)
15.3 183.9 GO:0030008 TRAPP complex(GO:0030008)
15.2 76.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
15.0 119.9 GO:0032133 chromosome passenger complex(GO:0032133)
14.8 74.2 GO:0033503 HULC complex(GO:0033503)
14.6 131.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
14.3 42.8 GO:1902636 kinociliary basal body(GO:1902636)
14.2 56.7 GO:0044611 nuclear pore inner ring(GO:0044611)
14.1 42.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
14.1 56.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
14.0 126.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
14.0 181.9 GO:0005662 DNA replication factor A complex(GO:0005662)
13.8 13.8 GO:0000811 GINS complex(GO:0000811)
13.8 41.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
13.7 95.7 GO:0002178 palmitoyltransferase complex(GO:0002178)
13.7 95.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
13.6 176.7 GO:0000815 ESCRT III complex(GO:0000815)
13.6 54.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
13.6 257.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
13.6 94.9 GO:0070531 BRCA1-A complex(GO:0070531)
13.2 52.9 GO:0070876 SOSS complex(GO:0070876)
13.2 356.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
13.1 144.1 GO:0036452 ESCRT complex(GO:0036452)
13.1 182.9 GO:0090543 Flemming body(GO:0090543)
13.1 65.3 GO:0009368 endopeptidase Clp complex(GO:0009368)
13.0 519.7 GO:0015934 large ribosomal subunit(GO:0015934)
12.9 142.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
12.9 90.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
12.8 89.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
12.8 128.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
12.7 229.2 GO:0005685 U1 snRNP(GO:0005685)
12.5 375.6 GO:0005680 anaphase-promoting complex(GO:0005680)
12.5 87.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
12.4 224.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
12.3 49.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
12.3 147.9 GO:0097433 dense body(GO:0097433)
12.3 85.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
12.2 48.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
12.2 232.1 GO:0036020 endolysosome membrane(GO:0036020)
12.2 122.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
12.0 84.2 GO:0031298 replication fork protection complex(GO:0031298)
11.9 785.9 GO:0015935 small ribosomal subunit(GO:0015935)
11.9 83.3 GO:0035861 site of double-strand break(GO:0035861)
11.8 129.4 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
11.7 82.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
11.7 70.3 GO:0070435 Shc-EGFR complex(GO:0070435)
11.7 128.8 GO:0030125 clathrin vesicle coat(GO:0030125)
11.6 92.9 GO:0042382 paraspeckles(GO:0042382)
11.6 34.8 GO:0031262 Ndc80 complex(GO:0031262)
11.5 80.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
11.4 34.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
11.4 136.6 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
11.3 45.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
11.2 44.8 GO:0032044 DSIF complex(GO:0032044)
11.2 122.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
11.0 143.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
11.0 11.0 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
11.0 87.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
10.8 21.6 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
10.8 75.5 GO:0030870 Mre11 complex(GO:0030870)
10.8 21.5 GO:0005905 clathrin-coated pit(GO:0005905)
10.7 53.7 GO:0032449 CBM complex(GO:0032449)
10.6 42.5 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
10.4 10.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
10.3 61.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
10.3 144.1 GO:0001673 male germ cell nucleus(GO:0001673)
10.3 143.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
10.2 20.5 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
10.2 61.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
10.2 50.9 GO:0035061 interchromatin granule(GO:0035061)
10.1 20.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
10.0 110.4 GO:0070765 gamma-secretase complex(GO:0070765)
10.0 897.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
9.8 39.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
9.7 300.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
9.5 408.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
9.5 483.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
9.5 85.2 GO:0005814 centriole(GO:0005814)
9.5 151.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
9.3 27.8 GO:0031523 Myb complex(GO:0031523)
9.1 73.0 GO:0032039 integrator complex(GO:0032039)
9.0 44.9 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
8.9 26.8 GO:0005839 proteasome core complex(GO:0005839)
8.9 62.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
8.9 88.9 GO:0001739 sex chromatin(GO:0001739)
8.9 35.5 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
8.9 894.8 GO:0035578 azurophil granule lumen(GO:0035578)
8.8 35.0 GO:0032301 MutSalpha complex(GO:0032301)
8.5 518.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
8.5 76.1 GO:0044194 cytolytic granule(GO:0044194)
8.4 58.6 GO:0061617 MICOS complex(GO:0061617)
8.3 91.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
8.1 32.5 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
8.1 16.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
8.1 32.3 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
8.0 31.8 GO:1990730 VCP-NSFL1C complex(GO:1990730)
8.0 620.1 GO:0005681 spliceosomal complex(GO:0005681)
7.8 62.8 GO:0000322 storage vacuole(GO:0000322)
7.8 7.8 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
7.8 101.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
7.8 23.3 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
7.7 139.4 GO:0001891 phagocytic cup(GO:0001891)
7.7 23.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
7.7 69.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
7.5 37.4 GO:1990425 ryanodine receptor complex(GO:1990425)
7.4 52.0 GO:0071203 WASH complex(GO:0071203)
7.4 73.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
7.2 43.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
7.1 28.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
7.1 128.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
7.1 540.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
7.1 77.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
7.1 49.4 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
7.0 28.0 GO:0070822 Sin3-type complex(GO:0070822)
7.0 195.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
6.8 440.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
6.6 33.1 GO:0030905 retromer, tubulation complex(GO:0030905)
6.6 13.2 GO:0042627 chylomicron(GO:0042627)
6.6 79.4 GO:0017119 Golgi transport complex(GO:0017119)
6.4 12.9 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
6.4 19.3 GO:0070939 Dsl1p complex(GO:0070939)
6.4 6.4 GO:1904724 tertiary granule lumen(GO:1904724)
6.3 38.0 GO:0032010 phagolysosome(GO:0032010)
6.3 897.1 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
6.3 213.1 GO:0090544 BAF-type complex(GO:0090544)
6.1 18.2 GO:1990393 3M complex(GO:1990393)
6.1 48.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
6.0 24.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
6.0 402.7 GO:0005643 nuclear pore(GO:0005643)
5.9 17.8 GO:1990423 RZZ complex(GO:1990423)
5.9 275.3 GO:0001772 immunological synapse(GO:0001772)
5.8 11.6 GO:0055087 Ski complex(GO:0055087)
5.8 17.3 GO:0005588 collagen type V trimer(GO:0005588)
5.7 120.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
5.7 244.0 GO:0005840 ribosome(GO:0005840)
5.7 73.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
5.6 61.3 GO:0032585 multivesicular body membrane(GO:0032585)
5.5 22.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
5.5 33.0 GO:0032009 early phagosome(GO:0032009)
5.3 47.5 GO:0016600 flotillin complex(GO:0016600)
5.2 5.2 GO:1990462 omegasome(GO:1990462)
5.2 25.9 GO:0001741 XY body(GO:0001741)
5.0 39.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
5.0 624.2 GO:0005795 Golgi stack(GO:0005795)
5.0 44.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
4.9 44.1 GO:0097413 Lewy body(GO:0097413)
4.7 9.5 GO:0045259 proton-transporting ATP synthase complex(GO:0045259)
4.7 74.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
4.6 13.9 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
4.6 4.6 GO:0044308 axonal spine(GO:0044308)
4.6 13.9 GO:0000798 nuclear cohesin complex(GO:0000798)
4.6 55.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
4.6 13.8 GO:0031415 NatA complex(GO:0031415)
4.5 17.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
4.4 52.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
4.4 8.8 GO:0005726 perichromatin fibrils(GO:0005726)
4.4 22.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
4.4 21.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
4.3 291.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
4.3 30.2 GO:0031264 death-inducing signaling complex(GO:0031264)
4.3 17.0 GO:1990031 pinceau fiber(GO:1990031)
4.2 12.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
4.2 21.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
4.2 92.9 GO:0098553 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
4.2 8.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
4.2 235.1 GO:0005871 kinesin complex(GO:0005871)
4.2 120.9 GO:0016469 proton-transporting two-sector ATPase complex(GO:0016469)
4.1 41.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
4.1 8.2 GO:0005826 actomyosin contractile ring(GO:0005826)
4.1 32.5 GO:0045335 phagocytic vesicle(GO:0045335)
4.0 20.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
4.0 20.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
4.0 51.9 GO:0031209 SCAR complex(GO:0031209)
3.9 321.9 GO:0017053 transcriptional repressor complex(GO:0017053)
3.8 18.9 GO:0071439 clathrin complex(GO:0071439)
3.8 3.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
3.7 326.2 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
3.7 232.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
3.7 115.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
3.7 84.5 GO:0000930 gamma-tubulin complex(GO:0000930)
3.6 14.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
3.6 378.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
3.6 25.2 GO:0070652 HAUS complex(GO:0070652)
3.5 17.6 GO:0044754 autolysosome(GO:0044754)
3.5 125.7 GO:0008180 COP9 signalosome(GO:0008180)
3.5 250.6 GO:0070821 tertiary granule membrane(GO:0070821)
3.5 6.9 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
3.5 3.5 GO:0000346 transcription export complex(GO:0000346)
3.4 20.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
3.4 27.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
3.4 20.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
3.4 10.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
3.3 23.3 GO:0072487 MSL complex(GO:0072487)
3.3 92.0 GO:0031258 lamellipodium membrane(GO:0031258)
3.3 6.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
3.2 6.5 GO:0002079 inner acrosomal membrane(GO:0002079)
3.2 19.4 GO:0005869 dynactin complex(GO:0005869)
3.2 1057.6 GO:0016607 nuclear speck(GO:0016607)
3.2 1223.5 GO:0005635 nuclear envelope(GO:0005635)
3.1 15.6 GO:0016589 NURF complex(GO:0016589)
3.1 12.5 GO:0031010 ISWI-type complex(GO:0031010)
3.0 15.2 GO:0043203 axon hillock(GO:0043203)
3.0 12.1 GO:0030891 VCB complex(GO:0030891)
2.9 11.8 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
2.9 126.3 GO:0035579 specific granule membrane(GO:0035579)
2.9 29.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
2.9 8.7 GO:0001652 granular component(GO:0001652)
2.9 11.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
2.9 5.7 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
2.8 39.7 GO:0031105 septin complex(GO:0031105)
2.8 5.7 GO:0051233 spindle midzone(GO:0051233)
2.8 39.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
2.8 55.9 GO:0005876 spindle microtubule(GO:0005876)
2.8 72.0 GO:0099738 cell cortex region(GO:0099738)
2.7 8.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
2.7 57.3 GO:0000502 proteasome complex(GO:0000502)
2.7 171.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
2.7 8.1 GO:0071748 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
2.7 239.0 GO:0016605 PML body(GO:0016605)
2.7 642.4 GO:0019866 organelle inner membrane(GO:0019866)
2.7 10.6 GO:0019815 B cell receptor complex(GO:0019815)
2.6 7.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
2.6 36.6 GO:0031932 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
2.6 5.2 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
2.5 28.0 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
2.4 60.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
2.3 21.1 GO:0034464 BBSome(GO:0034464)
2.3 39.5 GO:0002102 podosome(GO:0002102)
2.2 19.9 GO:0042588 zymogen granule(GO:0042588)
2.2 6.6 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
2.2 84.4 GO:0045095 keratin filament(GO:0045095)
2.1 8.3 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
2.1 4.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
2.0 51.1 GO:0070461 SAGA-type complex(GO:0070461)
1.9 250.2 GO:0031968 organelle outer membrane(GO:0031968)
1.9 11.5 GO:0097539 ciliary transition fiber(GO:0097539)
1.9 16.9 GO:0030904 retromer complex(GO:0030904)
1.9 48.7 GO:0045171 intercellular bridge(GO:0045171)
1.9 1.9 GO:0097542 ciliary tip(GO:0097542)
1.9 5.6 GO:0000803 sex chromosome(GO:0000803)
1.8 31.4 GO:0005719 nuclear euchromatin(GO:0005719)
1.8 5.5 GO:0005801 cis-Golgi network(GO:0005801)
1.8 14.6 GO:0005610 laminin-5 complex(GO:0005610)
1.8 10.7 GO:0032311 angiogenin-PRI complex(GO:0032311)
1.7 6.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.7 1.7 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
1.7 10.1 GO:0061689 tricellular tight junction(GO:0061689)
1.7 58.5 GO:0019814 immunoglobulin complex(GO:0019814)
1.7 5.0 GO:0031088 platelet dense granule membrane(GO:0031088)
1.7 6.6 GO:0070187 telosome(GO:0070187)
1.6 4.9 GO:0070578 RISC-loading complex(GO:0070578)
1.6 14.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
1.6 316.9 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.6 1.6 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
1.6 16.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
1.6 3.2 GO:0070938 contractile ring(GO:0070938)
1.6 25.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
1.5 3679.6 GO:0070062 extracellular exosome(GO:0070062)
1.4 21.1 GO:0035580 specific granule lumen(GO:0035580)
1.4 4.2 GO:0031201 SNARE complex(GO:0031201)
1.4 108.8 GO:0005819 spindle(GO:0005819)
1.4 1.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
1.4 24.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
1.4 5.4 GO:0045178 basal part of cell(GO:0045178)
1.3 5.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
1.2 6.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
1.2 2.5 GO:0032389 MutLalpha complex(GO:0032389)
1.2 44.1 GO:0043198 dendritic shaft(GO:0043198)
1.2 5.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.2 13.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.2 3.5 GO:0032279 asymmetric synapse(GO:0032279)
1.1 3.4 GO:0031528 microvillus membrane(GO:0031528)
1.1 12.1 GO:0005844 polysome(GO:0005844)
1.1 7.6 GO:0015629 actin cytoskeleton(GO:0015629)
1.1 40.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
1.1 12.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
1.1 6.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
1.0 21.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
1.0 9.0 GO:0042101 T cell receptor complex(GO:0042101)
1.0 18.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.9 6.6 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.9 13.1 GO:0097346 INO80-type complex(GO:0097346)
0.9 2.8 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.9 41.8 GO:0030175 filopodium(GO:0030175)
0.9 58.1 GO:0000922 spindle pole(GO:0000922)
0.8 2.4 GO:0005960 glycine cleavage complex(GO:0005960)
0.8 13.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.8 10.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.8 35.7 GO:0005903 brush border(GO:0005903)
0.8 3.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.8 18.1 GO:0005901 caveola(GO:0005901)
0.7 7.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.7 11.1 GO:0005657 replication fork(GO:0005657)
0.6 1.3 GO:0042827 platelet dense granule(GO:0042827)
0.6 1.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.6 7.1 GO:0031430 M band(GO:0031430)
0.6 2.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.6 9.0 GO:0031902 late endosome membrane(GO:0031902)
0.6 5.0 GO:0005605 basal lamina(GO:0005605)
0.5 5.9 GO:0000145 exocyst(GO:0000145)
0.4 1.7 GO:0071141 SMAD protein complex(GO:0071141)
0.4 2.9 GO:0097228 sperm principal piece(GO:0097228)
0.4 1.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.4 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 1.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 1.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 27.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 3.3 GO:0032982 myosin filament(GO:0032982)
0.2 7.2 GO:0016363 nuclear matrix(GO:0016363)
0.2 0.9 GO:0097443 sorting endosome(GO:0097443)
0.1 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.1 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 4.3 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 62.0 GO:0005739 mitochondrion(GO:0005739)
0.1 0.4 GO:0044292 dendrite terminus(GO:0044292)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
129.7 389.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
76.8 383.8 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
64.8 194.5 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
56.8 113.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
56.5 338.7 GO:0030621 U4 snRNA binding(GO:0030621)
55.8 167.3 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
53.8 161.3 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
52.6 526.5 GO:0070990 snRNP binding(GO:0070990)
51.3 153.8 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
51.0 306.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
48.3 96.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
48.3 144.8 GO:0042134 rRNA primary transcript binding(GO:0042134)
46.3 185.1 GO:0032217 riboflavin transporter activity(GO:0032217)
43.8 1313.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
38.2 420.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
38.1 114.3 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
38.0 190.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
37.7 113.2 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
37.1 111.4 GO:0034511 U3 snoRNA binding(GO:0034511)
36.7 183.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
36.5 109.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
35.4 283.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
35.1 105.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
34.2 102.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
33.9 304.7 GO:0008312 7S RNA binding(GO:0008312)
33.7 134.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
33.7 269.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
33.4 133.5 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
33.0 198.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
32.7 327.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
31.8 190.8 GO:0005346 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
31.5 189.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
30.6 275.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
30.3 30.3 GO:0048256 flap endonuclease activity(GO:0048256)
29.6 326.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
29.6 118.4 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
29.5 88.4 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
29.4 88.1 GO:0001069 regulatory region RNA binding(GO:0001069)
28.9 231.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
28.8 633.4 GO:0000339 RNA cap binding(GO:0000339)
28.7 200.6 GO:0030620 U2 snRNA binding(GO:0030620)
27.8 111.3 GO:0002060 purine nucleobase binding(GO:0002060)
27.7 83.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
27.2 81.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
26.8 26.8 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
26.1 78.4 GO:0017130 poly(C) RNA binding(GO:0017130)
26.0 26.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
25.8 129.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
25.3 151.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
24.9 174.6 GO:0061133 endopeptidase activator activity(GO:0061133)
23.7 94.9 GO:0005046 KDEL sequence binding(GO:0005046)
23.0 183.7 GO:0000405 bubble DNA binding(GO:0000405)
22.8 159.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
22.3 490.5 GO:0042609 CD4 receptor binding(GO:0042609)
22.0 66.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
21.9 21.9 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
21.8 130.5 GO:0042296 ISG15 transferase activity(GO:0042296)
21.5 64.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
21.4 85.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
21.2 1359.0 GO:0003743 translation initiation factor activity(GO:0003743)
20.9 83.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
20.8 83.3 GO:0004774 succinate-CoA ligase activity(GO:0004774)
20.7 62.2 GO:0004730 pseudouridylate synthase activity(GO:0004730)
20.6 82.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
20.6 61.7 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
20.3 101.7 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
20.3 81.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
20.3 142.0 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
20.2 80.7 GO:0016748 succinyltransferase activity(GO:0016748)
20.2 40.3 GO:0048039 ubiquinone binding(GO:0048039)
19.8 138.8 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
19.7 59.2 GO:0032184 SUMO polymer binding(GO:0032184)
19.6 137.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
19.6 78.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
19.3 115.7 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
19.2 57.6 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
19.0 133.2 GO:0050815 phosphoserine binding(GO:0050815)
18.9 113.3 GO:0016531 copper chaperone activity(GO:0016531)
18.6 149.0 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
18.5 74.2 GO:0004594 pantothenate kinase activity(GO:0004594)
18.5 55.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
18.5 535.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
17.6 369.7 GO:0001055 RNA polymerase II activity(GO:0001055)
17.5 227.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
17.0 101.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
16.9 84.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
16.9 118.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
16.8 50.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
16.4 213.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
16.4 196.5 GO:0031386 protein tag(GO:0031386)
16.2 259.7 GO:0008179 adenylate cyclase binding(GO:0008179)
16.1 64.5 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
16.1 64.5 GO:0004132 dCMP deaminase activity(GO:0004132)
15.9 159.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
15.9 15.9 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
15.6 109.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
15.3 45.9 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
15.2 91.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
15.2 30.3 GO:0046979 TAP2 binding(GO:0046979)
14.9 59.7 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
14.8 59.3 GO:0044388 small protein activating enzyme binding(GO:0044388)
14.8 44.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
14.8 29.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
14.7 102.8 GO:0043208 glycosphingolipid binding(GO:0043208)
14.6 43.9 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
14.6 131.1 GO:0035174 histone serine kinase activity(GO:0035174)
14.5 72.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
14.4 201.8 GO:0016018 cyclosporin A binding(GO:0016018)
14.3 85.5 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
14.2 56.8 GO:0004566 beta-glucuronidase activity(GO:0004566)
14.0 42.1 GO:0004016 adenylate cyclase activity(GO:0004016) guanylate cyclase activity(GO:0004383)
14.0 56.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
14.0 83.9 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
14.0 125.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
14.0 83.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
13.8 82.5 GO:0015266 protein channel activity(GO:0015266)
13.7 109.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
13.6 40.8 GO:0032089 NACHT domain binding(GO:0032089)
13.4 2787.3 GO:0003735 structural constituent of ribosome(GO:0003735)
13.4 40.2 GO:0004170 dUTP diphosphatase activity(GO:0004170)
13.3 307.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
13.3 26.6 GO:0097677 STAT family protein binding(GO:0097677)
13.3 53.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
13.2 13.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
13.2 52.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
13.1 564.8 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
13.1 52.3 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
13.1 26.1 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
13.0 52.0 GO:0004743 pyruvate kinase activity(GO:0004743)
12.9 219.3 GO:0005537 mannose binding(GO:0005537)
12.9 205.8 GO:0008266 poly(U) RNA binding(GO:0008266)
12.8 128.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
12.8 192.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
12.8 64.0 GO:0030348 syntaxin-3 binding(GO:0030348)
12.8 319.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
12.8 38.3 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
12.7 344.0 GO:0017025 TBP-class protein binding(GO:0017025)
12.7 12.7 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
12.6 50.6 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
12.6 37.7 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
12.5 50.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
12.5 49.9 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
12.4 37.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
12.3 49.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
12.3 24.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
12.2 110.0 GO:0046790 virion binding(GO:0046790)
12.2 61.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
12.0 72.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
11.9 273.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
11.9 201.7 GO:0043495 protein anchor(GO:0043495)
11.9 23.7 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
11.8 82.4 GO:0050733 RS domain binding(GO:0050733)
11.7 70.3 GO:0048408 epidermal growth factor binding(GO:0048408)
11.7 35.1 GO:0070538 oleic acid binding(GO:0070538)
11.7 46.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
11.6 23.2 GO:0032143 single thymine insertion binding(GO:0032143)
11.6 58.0 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
11.6 255.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
11.6 139.0 GO:0089720 caspase binding(GO:0089720)
11.5 34.4 GO:0030984 kininogen binding(GO:0030984)
11.4 194.2 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
11.4 22.8 GO:0000403 Y-form DNA binding(GO:0000403)
11.3 45.4 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
11.3 45.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
11.2 67.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
11.2 145.8 GO:0030957 Tat protein binding(GO:0030957)
11.2 44.7 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
11.1 311.6 GO:0005123 death receptor binding(GO:0005123)
11.1 166.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
11.0 55.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
11.0 88.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
11.0 87.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
10.9 32.7 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
10.9 21.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
10.9 32.6 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
10.8 32.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
10.7 559.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
10.7 32.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
10.7 106.6 GO:0019237 centromeric DNA binding(GO:0019237)
10.7 10.7 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
10.6 116.5 GO:0030515 snoRNA binding(GO:0030515)
10.6 52.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
10.6 42.2 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
10.6 31.7 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
10.5 42.1 GO:0016936 galactoside binding(GO:0016936)
10.5 147.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
10.5 52.6 GO:0043120 tumor necrosis factor binding(GO:0043120)
10.4 20.8 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
10.4 41.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
10.4 83.3 GO:0008097 5S rRNA binding(GO:0008097)
10.4 135.0 GO:0050786 RAGE receptor binding(GO:0050786)
10.3 20.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
10.3 51.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
10.2 61.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
10.1 30.2 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
10.1 221.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
10.0 140.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
10.0 941.0 GO:0003697 single-stranded DNA binding(GO:0003697)
9.9 29.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
9.9 39.6 GO:0004348 glucosylceramidase activity(GO:0004348)
9.8 107.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
9.7 19.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
9.7 29.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
9.7 29.1 GO:0032090 Pyrin domain binding(GO:0032090)
9.6 67.2 GO:0001054 RNA polymerase I activity(GO:0001054)
9.6 19.2 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
9.6 28.7 GO:0004917 interleukin-7 receptor activity(GO:0004917)
9.6 66.9 GO:0004301 epoxide hydrolase activity(GO:0004301)
9.5 9.5 GO:0001540 beta-amyloid binding(GO:0001540)
9.5 302.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
9.4 28.3 GO:0036033 mediator complex binding(GO:0036033)
9.4 37.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
9.4 37.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
9.3 140.1 GO:0032036 myosin heavy chain binding(GO:0032036)
9.3 390.9 GO:0050699 WW domain binding(GO:0050699)
9.3 27.9 GO:0098770 FBXO family protein binding(GO:0098770)
9.3 18.6 GO:0003998 acylphosphatase activity(GO:0003998)
9.3 83.5 GO:1990226 histone methyltransferase binding(GO:1990226)
9.2 202.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
9.1 63.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
9.0 27.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
9.0 45.0 GO:0002046 opsin binding(GO:0002046)
9.0 17.9 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
8.9 169.7 GO:0051400 BH domain binding(GO:0051400)
8.9 62.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
8.9 124.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
8.9 44.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
8.9 35.4 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
8.7 34.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
8.6 43.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
8.6 68.6 GO:1901612 cardiolipin binding(GO:1901612)
8.5 67.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
8.5 67.8 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
8.5 228.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
8.5 16.9 GO:0000828 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
8.5 194.7 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
8.3 339.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
8.2 49.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
8.2 41.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
8.2 24.6 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
8.2 8.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
8.2 32.8 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
8.1 80.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
8.0 8.0 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
8.0 32.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
8.0 47.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
7.7 15.4 GO:0042979 ornithine decarboxylase activator activity(GO:0042978) ornithine decarboxylase regulator activity(GO:0042979)
7.6 30.6 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
7.6 15.3 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
7.6 152.4 GO:0008327 methyl-CpG binding(GO:0008327)
7.5 52.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
7.4 44.4 GO:0035500 MH2 domain binding(GO:0035500)
7.3 29.4 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
7.3 431.4 GO:0019003 GDP binding(GO:0019003)
7.3 21.9 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
7.3 29.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
7.3 246.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
7.3 7.3 GO:0001727 lipid kinase activity(GO:0001727)
7.2 28.9 GO:0015140 malate transmembrane transporter activity(GO:0015140)
7.1 42.7 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
7.1 28.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
7.1 78.1 GO:0017070 U6 snRNA binding(GO:0017070)
7.1 63.6 GO:0050700 CARD domain binding(GO:0050700)
7.0 7.0 GO:0019961 interferon binding(GO:0019961)
6.9 172.1 GO:0031489 myosin V binding(GO:0031489)
6.8 27.3 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
6.6 6.6 GO:0008384 IkappaB kinase activity(GO:0008384)
6.6 46.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
6.6 39.8 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
6.6 19.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
6.5 39.1 GO:0019776 Atg8 ligase activity(GO:0019776)
6.4 32.0 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
6.2 49.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
6.2 18.6 GO:0004766 spermidine synthase activity(GO:0004766)
6.2 43.5 GO:0035197 siRNA binding(GO:0035197)
6.2 43.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
6.2 24.8 GO:0000400 four-way junction DNA binding(GO:0000400)
6.2 37.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
6.2 308.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
6.2 24.7 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
6.1 6.1 GO:0004913 interleukin-4 receptor activity(GO:0004913)
6.1 169.5 GO:0001671 ATPase activator activity(GO:0001671)
6.0 6.0 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
6.0 107.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
6.0 35.8 GO:0047685 amine sulfotransferase activity(GO:0047685)
6.0 77.5 GO:0003688 DNA replication origin binding(GO:0003688)
5.9 76.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
5.9 118.0 GO:0042288 MHC class I protein binding(GO:0042288)
5.8 40.6 GO:0070087 chromo shadow domain binding(GO:0070087)
5.8 34.6 GO:1990254 keratin filament binding(GO:1990254)
5.8 178.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
5.7 80.3 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
5.7 17.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
5.7 39.9 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
5.7 11.4 GO:1990837 sequence-specific double-stranded DNA binding(GO:1990837)
5.5 16.6 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
5.5 16.6 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
5.5 27.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
5.5 16.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
5.4 326.3 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
5.4 16.3 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
5.4 43.4 GO:0005522 profilin binding(GO:0005522)
5.4 509.6 GO:0043130 ubiquitin binding(GO:0043130)
5.4 10.8 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
5.3 58.6 GO:0004312 fatty acid synthase activity(GO:0004312)
5.3 69.3 GO:0070628 proteasome binding(GO:0070628)
5.3 26.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
5.3 116.6 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
5.3 31.7 GO:0003796 lysozyme activity(GO:0003796)
5.3 15.9 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
5.3 31.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
5.3 47.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
5.3 47.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
5.3 15.8 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
5.2 105.0 GO:0070064 proline-rich region binding(GO:0070064)
5.2 99.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
5.2 15.7 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
5.2 15.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
5.2 26.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
5.2 93.3 GO:0097602 cullin family protein binding(GO:0097602)
5.2 31.1 GO:0036310 annealing helicase activity(GO:0036310)
5.2 36.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
5.2 82.4 GO:0043422 protein kinase B binding(GO:0043422)
5.1 138.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
5.1 20.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
5.1 15.3 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
5.1 15.3 GO:0030613 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
5.1 15.3 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
5.1 126.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
5.0 40.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
5.0 15.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
5.0 20.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
5.0 90.5 GO:0031404 chloride ion binding(GO:0031404)
5.0 14.9 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
5.0 10.0 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345)
5.0 34.8 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
4.9 9.8 GO:0032552 deoxyribonucleotide binding(GO:0032552)
4.9 24.5 GO:1990460 leptin receptor binding(GO:1990460)
4.9 24.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
4.9 39.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
4.9 136.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
4.8 33.9 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
4.8 101.6 GO:0008242 omega peptidase activity(GO:0008242)
4.8 19.3 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
4.8 19.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
4.7 18.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
4.7 542.1 GO:0047485 protein N-terminus binding(GO:0047485)
4.7 47.1 GO:0019534 toxin transporter activity(GO:0019534)
4.7 204.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
4.6 60.4 GO:0031491 nucleosome binding(GO:0031491)
4.6 166.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
4.6 23.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
4.6 13.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
4.6 442.1 GO:0008565 protein transporter activity(GO:0008565)
4.5 13.6 GO:0004914 interleukin-5 receptor activity(GO:0004914)
4.5 35.6 GO:0070878 primary miRNA binding(GO:0070878)
4.5 17.8 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
4.4 44.3 GO:0048156 tau protein binding(GO:0048156)
4.4 79.1 GO:0017049 GTP-Rho binding(GO:0017049)
4.4 21.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
4.4 43.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
4.4 95.8 GO:0036002 pre-mRNA binding(GO:0036002)
4.3 8.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
4.3 56.5 GO:0019992 diacylglycerol binding(GO:0019992)
4.3 90.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
4.3 8.6 GO:0070644 vitamin D response element binding(GO:0070644)
4.3 17.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
4.3 21.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
4.3 8.6 GO:0004167 dopachrome isomerase activity(GO:0004167)
4.3 76.8 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
4.3 208.5 GO:0035064 methylated histone binding(GO:0035064)
4.2 12.7 GO:0048030 disaccharide binding(GO:0048030)
4.2 8.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
4.2 75.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
4.2 46.0 GO:0050321 tau-protein kinase activity(GO:0050321)
4.2 8.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
4.2 12.5 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
4.1 153.5 GO:0005484 SNAP receptor activity(GO:0005484)
4.1 173.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
4.1 102.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
4.1 57.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
4.0 28.0 GO:0004849 uridine kinase activity(GO:0004849)
3.9 19.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
3.9 47.1 GO:0003680 AT DNA binding(GO:0003680)
3.9 70.1 GO:0004177 aminopeptidase activity(GO:0004177)
3.9 11.7 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
3.9 7.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
3.9 223.7 GO:0003725 double-stranded RNA binding(GO:0003725)
3.8 26.7 GO:0030274 LIM domain binding(GO:0030274)
3.8 11.3 GO:0004958 prostaglandin F receptor activity(GO:0004958)
3.8 56.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
3.7 7.5 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
3.7 788.0 GO:0051015 actin filament binding(GO:0051015)
3.7 22.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
3.7 22.1 GO:0019238 cyclohydrolase activity(GO:0019238)
3.7 14.7 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
3.7 14.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
3.6 58.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
3.6 105.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
3.6 3.6 GO:0097001 ceramide binding(GO:0097001)
3.6 14.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
3.6 28.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
3.6 10.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
3.6 39.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
3.6 114.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
3.6 3.6 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
3.5 7.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
3.5 21.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
3.5 96.9 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
3.4 10.3 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
3.4 30.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
3.4 10.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
3.4 57.2 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
3.3 9.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
3.3 88.6 GO:0005540 hyaluronic acid binding(GO:0005540)
3.1 22.0 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
3.1 25.1 GO:0034594 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
3.1 25.0 GO:0004470 malic enzyme activity(GO:0004470)
3.1 3.1 GO:0099609 microtubule lateral binding(GO:0099609)
3.1 12.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
3.1 18.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
3.1 27.7 GO:0019213 deacetylase activity(GO:0019213)
3.0 33.4 GO:0032395 MHC class II receptor activity(GO:0032395)
3.0 9.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
3.0 15.0 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
3.0 77.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
3.0 50.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
3.0 20.9 GO:0004920 interleukin-10 receptor activity(GO:0004920)
3.0 6.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
3.0 3197.5 GO:0003723 RNA binding(GO:0003723)
3.0 67.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
2.9 66.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
2.9 8.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
2.8 2.8 GO:0051185 coenzyme transporter activity(GO:0051185)
2.8 42.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
2.8 11.3 GO:0070051 fibrinogen binding(GO:0070051)
2.8 30.9 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
2.8 14.0 GO:0032407 mismatch repair complex binding(GO:0032404) MutSalpha complex binding(GO:0032407)
2.7 8.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
2.7 8.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.7 30.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
2.7 26.9 GO:0046527 glucosyltransferase activity(GO:0046527)
2.7 45.7 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
2.7 10.7 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
2.7 2.7 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
2.7 8.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
2.7 34.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
2.6 68.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
2.6 36.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
2.6 18.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
2.6 20.7 GO:1990763 arrestin family protein binding(GO:1990763)
2.6 5.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
2.5 38.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
2.5 12.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
2.5 38.1 GO:0000149 SNARE binding(GO:0000149)
2.5 5.0 GO:0048406 nerve growth factor binding(GO:0048406)
2.5 66.6 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
2.4 55.8 GO:0051879 Hsp90 protein binding(GO:0051879)
2.4 11.9 GO:0051861 glycolipid binding(GO:0051861)
2.4 149.4 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
2.3 83.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
2.3 6.9 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
2.3 6.9 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
2.3 27.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
2.2 129.4 GO:0051082 unfolded protein binding(GO:0051082)
2.2 15.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
2.2 15.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.2 24.3 GO:0005131 growth hormone receptor binding(GO:0005131)
2.2 10.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
2.1 6.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
2.1 40.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
2.1 100.7 GO:0017080 sodium channel regulator activity(GO:0017080)
2.0 4.0 GO:0001849 complement component C1q binding(GO:0001849)
2.0 5.9 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
1.9 5.8 GO:0030366 molybdopterin synthase activity(GO:0030366)
1.9 11.5 GO:0015288 porin activity(GO:0015288)
1.9 32.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.9 13.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
1.9 9.4 GO:0019863 IgE binding(GO:0019863)
1.9 20.6 GO:0016413 O-acetyltransferase activity(GO:0016413)
1.8 71.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
1.8 5.5 GO:0033149 FFAT motif binding(GO:0033149)
1.8 5.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.8 14.5 GO:0035325 Toll-like receptor binding(GO:0035325)
1.8 9.0 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
1.8 3.6 GO:0016417 S-acyltransferase activity(GO:0016417)
1.8 7.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
1.8 10.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
1.8 1.8 GO:0048185 activin binding(GO:0048185)
1.8 28.7 GO:0048365 Rac GTPase binding(GO:0048365)
1.8 12.4 GO:0004180 carboxypeptidase activity(GO:0004180)
1.8 12.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
1.7 5.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.7 8.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.7 20.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
1.7 5.0 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
1.7 25.1 GO:0042605 peptide antigen binding(GO:0042605)
1.7 5.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.6 6.5 GO:0000182 rDNA binding(GO:0000182)
1.6 222.3 GO:0005178 integrin binding(GO:0005178)
1.6 8.0 GO:0070840 dynein complex binding(GO:0070840)
1.6 8.0 GO:0034452 dynactin binding(GO:0034452)
1.6 4.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.6 4.7 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
1.6 9.3 GO:0008046 axon guidance receptor activity(GO:0008046)
1.5 3.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
1.5 9.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.5 6.1 GO:0001047 core promoter binding(GO:0001047)
1.5 33.2 GO:0008235 metalloexopeptidase activity(GO:0008235)
1.5 80.0 GO:0042393 histone binding(GO:0042393)
1.5 25.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
1.5 2.9 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.5 2.9 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.4 13.0 GO:0043560 insulin receptor substrate binding(GO:0043560)
1.4 76.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
1.4 11.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.4 18.6 GO:0008536 Ran GTPase binding(GO:0008536)
1.4 8.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.4 11.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
1.4 59.7 GO:0008276 protein methyltransferase activity(GO:0008276)
1.4 7.0 GO:0047820 D-glutamate cyclase activity(GO:0047820)
1.4 5.6 GO:0043515 kinetochore binding(GO:0043515)
1.4 5.5 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
1.4 20.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
1.4 4.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
1.4 13.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.3 4.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
1.3 9.2 GO:0070403 NAD+ binding(GO:0070403)
1.3 11.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
1.3 14.2 GO:0033038 bitter taste receptor activity(GO:0033038)
1.3 12.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.3 25.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.3 17.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
1.3 1.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
1.3 3.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
1.2 9.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.2 3.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.2 3.7 GO:0023023 MHC protein complex binding(GO:0023023)
1.2 256.4 GO:0003924 GTPase activity(GO:0003924)
1.2 7.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
1.2 5.9 GO:0004771 sterol esterase activity(GO:0004771)
1.2 86.5 GO:0003777 microtubule motor activity(GO:0003777)
1.2 2.3 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
1.2 5.8 GO:0010465 nerve growth factor receptor activity(GO:0010465)
1.2 2.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.2 10.4 GO:0004985 opioid receptor activity(GO:0004985)
1.2 57.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
1.1 6.6 GO:0039552 RIG-I binding(GO:0039552)
1.1 6.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.1 14.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
1.1 3.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.1 14.1 GO:0051059 NF-kappaB binding(GO:0051059)
1.1 4.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
1.1 8.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.1 3.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
1.1 3.2 GO:0005000 vasopressin receptor activity(GO:0005000)
1.0 2.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.0 4.2 GO:0031208 POZ domain binding(GO:0031208)
1.0 4.2 GO:0016499 orexin receptor activity(GO:0016499)
1.0 6.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.0 19.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
1.0 50.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
1.0 39.1 GO:0005507 copper ion binding(GO:0005507)
1.0 10.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.0 4.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.0 14.2 GO:0030280 structural constituent of epidermis(GO:0030280)
1.0 7.1 GO:0043426 MRF binding(GO:0043426)
1.0 63.2 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
1.0 2.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
1.0 3.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.9 3.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.9 3.6 GO:0017018 myosin phosphatase activity(GO:0017018)
0.9 18.8 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.9 1.8 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.9 15.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.9 2.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.9 10.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.8 1.7 GO:0043532 angiostatin binding(GO:0043532)
0.8 5.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.8 48.8 GO:0032947 protein complex scaffold(GO:0032947)
0.8 2.4 GO:0043559 insulin binding(GO:0043559)
0.8 18.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.8 9.3 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.8 17.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.8 22.8 GO:0002039 p53 binding(GO:0002039)
0.7 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.7 5.7 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.7 6.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.7 15.4 GO:0042169 SH2 domain binding(GO:0042169)
0.7 12.6 GO:0050811 GABA receptor binding(GO:0050811)
0.7 170.1 GO:0008236 serine-type peptidase activity(GO:0008236)
0.7 2.0 GO:0098821 BMP receptor activity(GO:0098821)
0.7 3.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.7 16.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.7 5.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.7 1.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.6 7.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.6 1.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.6 6.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6 1.9 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.6 1.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.6 8.4 GO:0051087 chaperone binding(GO:0051087)
0.6 1.8 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.6 1.2 GO:0016886 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) ligase activity, forming phosphoric ester bonds(GO:0016886)
0.6 4.7 GO:0042731 PH domain binding(GO:0042731)
0.6 10.5 GO:0051117 ATPase binding(GO:0051117)
0.6 10.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.6 2.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.6 1.7 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.5 2.2 GO:0032190 acrosin binding(GO:0032190)
0.5 4.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.5 8.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 2.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.5 2.0 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.5 3.0 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.5 1.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.5 1.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.5 1.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5 1.9 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.5 1.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.5 0.5 GO:0097027 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) ubiquitin-protein transferase activator activity(GO:0097027)
0.4 1.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 6.1 GO:0019864 IgG binding(GO:0019864)
0.4 3.0 GO:0008199 ferric iron binding(GO:0008199)
0.4 2.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.4 1.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 5.0 GO:0031072 heat shock protein binding(GO:0031072)
0.4 4.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.4 2.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.4 2.7 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.4 2.3 GO:0005518 collagen binding(GO:0005518)
0.4 1.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 9.8 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.3 6.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 3.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 2.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.3 2.0 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.3 6.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 101.7 GO:0019900 kinase binding(GO:0019900)
0.3 29.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 8.9 GO:0015485 cholesterol binding(GO:0015485)
0.3 0.9 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 2.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 2.7 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.3 1.1 GO:0004966 galanin receptor activity(GO:0004966)
0.3 10.5 GO:0009055 electron carrier activity(GO:0009055)
0.3 1.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 1.5 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 3.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 0.7 GO:0003883 CTP synthase activity(GO:0003883)
0.2 2.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 4.9 GO:0019956 chemokine binding(GO:0019956)
0.2 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 3.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 27.8 GO:0030246 carbohydrate binding(GO:0030246)
0.2 1.2 GO:0015250 water channel activity(GO:0015250)
0.2 5.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 4.2 GO:0003774 motor activity(GO:0003774)
0.2 60.3 GO:0003712 transcription cofactor activity(GO:0003712)
0.2 1.0 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.2 1.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 1.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 1.2 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 3.7 GO:0043621 protein self-association(GO:0043621)
0.1 2.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.0 GO:0030276 clathrin binding(GO:0030276)
0.1 10.7 GO:0005262 calcium channel activity(GO:0005262)
0.1 13.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 1.8 GO:0042805 actinin binding(GO:0042805)
0.1 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.1 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 2.1 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 132.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
13.9 582.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
12.8 38.5 PID TRAIL PATHWAY TRAIL signaling pathway
11.7 349.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
11.1 321.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
10.4 855.8 PID RAC1 PATHWAY RAC1 signaling pathway
10.0 658.4 PID ATR PATHWAY ATR signaling pathway
9.8 9.8 PID S1P S1P1 PATHWAY S1P1 pathway
8.3 698.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
8.1 32.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
8.1 226.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
8.0 393.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
7.8 209.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
7.7 478.4 PID AURORA B PATHWAY Aurora B signaling
7.3 7.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
7.0 105.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
7.0 7.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
6.8 68.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
6.7 517.6 PID ILK PATHWAY Integrin-linked kinase signaling
6.6 629.8 PID E2F PATHWAY E2F transcription factor network
6.6 488.1 PID P53 REGULATION PATHWAY p53 pathway
6.4 238.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
6.4 255.8 PID PLK1 PATHWAY PLK1 signaling events
6.1 201.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
6.0 366.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
5.9 35.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
5.8 58.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
5.8 219.4 PID ALK1 PATHWAY ALK1 signaling events
5.4 185.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
5.3 112.2 PID ARF 3PATHWAY Arf1 pathway
5.2 20.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
4.8 154.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
4.6 91.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
4.5 8.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
4.4 440.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
4.3 95.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
3.9 147.4 PID TNF PATHWAY TNF receptor signaling pathway
3.8 19.2 PID ERBB4 PATHWAY ErbB4 signaling events
3.8 95.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
3.8 176.6 PID IL6 7 PATHWAY IL6-mediated signaling events
3.8 108.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
3.7 66.9 PID AURORA A PATHWAY Aurora A signaling
3.5 60.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
3.3 16.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
3.3 32.9 PID ATM PATHWAY ATM pathway
3.2 95.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
3.1 132.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
3.1 75.0 PID IL1 PATHWAY IL1-mediated signaling events
3.1 3.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
3.0 71.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
2.9 34.9 PID S1P S1P4 PATHWAY S1P4 pathway
2.8 68.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
2.8 33.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
2.7 44.0 PID CD40 PATHWAY CD40/CD40L signaling
2.6 49.4 PID IFNG PATHWAY IFN-gamma pathway
2.6 124.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
2.6 63.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
2.5 17.6 PID WNT SIGNALING PATHWAY Wnt signaling network
2.5 211.4 PID CMYB PATHWAY C-MYB transcription factor network
2.4 76.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
2.4 43.2 PID INSULIN PATHWAY Insulin Pathway
2.4 343.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
2.3 161.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
2.3 78.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
2.3 126.4 PID HNF3A PATHWAY FOXA1 transcription factor network
2.3 18.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
2.2 20.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
2.2 13.3 PID FAS PATHWAY FAS (CD95) signaling pathway
2.0 14.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
2.0 69.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
1.9 23.3 PID IL3 PATHWAY IL3-mediated signaling events
1.8 11.0 ST G ALPHA S PATHWAY G alpha s Pathway
1.8 3.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
1.8 111.5 PID RHOA REG PATHWAY Regulation of RhoA activity
1.7 38.1 PID ATF2 PATHWAY ATF-2 transcription factor network
1.7 58.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
1.7 41.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.6 68.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.6 65.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
1.4 33.8 PID IL4 2PATHWAY IL4-mediated signaling events
1.3 17.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
1.3 20.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.3 28.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
1.2 43.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
1.2 25.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
1.2 7.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
1.1 3.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.1 14.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
1.1 15.9 PID IL2 1PATHWAY IL2-mediated signaling events
1.0 11.4 PID FOXO PATHWAY FoxO family signaling
0.9 25.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.9 5.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.9 9.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.8 32.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.8 8.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.8 6.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.8 25.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.7 12.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.7 17.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.7 2.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.6 5.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.6 20.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.6 4.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.6 5.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.5 12.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.5 3.8 PID REELIN PATHWAY Reelin signaling pathway
0.5 21.2 PID P73PATHWAY p73 transcription factor network
0.5 6.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.5 13.4 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.4 2.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 10.6 PID CDC42 PATHWAY CDC42 signaling events
0.4 21.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.4 5.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.4 89.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 1.6 PID BARD1 PATHWAY BARD1 signaling events
0.4 7.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.4 1.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.3 3.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.3 4.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 1.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 3.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
39.5 632.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
36.5 328.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
35.3 2609.8 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
26.4 263.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
25.6 920.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
24.4 391.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
24.1 1833.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
23.9 23.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
22.2 642.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
21.9 131.4 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
21.8 522.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
21.0 2807.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
20.9 480.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
20.9 20.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
18.8 469.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
18.2 382.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
17.8 285.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
16.7 699.5 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
16.4 540.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
16.4 523.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
16.0 224.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
15.1 225.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
15.0 180.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
14.8 575.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
14.7 29.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
14.5 1489.3 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
13.7 219.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
13.2 383.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
12.7 202.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
12.6 390.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
12.2 24.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
12.1 242.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
11.8 695.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
11.7 11.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
11.5 368.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
10.5 52.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
10.4 352.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
10.2 193.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
10.0 129.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
10.0 328.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
9.9 168.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
9.8 254.5 REACTOME KINESINS Genes involved in Kinesins
9.7 164.8 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
9.7 774.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
9.4 131.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
9.3 315.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
9.2 174.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
9.1 63.4 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
8.9 384.2 REACTOME TRANSLATION Genes involved in Translation
8.7 443.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
8.7 182.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
8.6 129.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
8.4 160.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
8.4 218.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
8.3 247.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
7.9 198.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
7.7 271.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
7.6 428.3 REACTOME G1 PHASE Genes involved in G1 Phase
7.6 84.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
7.6 152.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
7.5 193.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
7.0 49.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
7.0 20.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
6.8 47.8 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
6.6 138.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
6.5 52.4 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
6.4 90.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
6.4 147.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
6.2 55.8 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
6.1 128.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
6.1 54.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
5.9 465.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
5.8 23.1 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
5.7 17.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
5.6 118.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
5.6 223.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
5.5 154.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
5.4 784.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
5.3 159.4 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
5.1 97.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
5.0 20.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
5.0 15.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
5.0 119.7 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
4.9 88.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
4.9 39.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
4.8 62.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
4.7 135.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
4.3 78.2 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
4.3 60.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
4.2 62.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
4.2 29.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
4.2 128.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
4.0 16.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
4.0 4.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
4.0 158.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
4.0 71.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
3.8 65.3 REACTOME METABOLISM OF NUCLEOTIDES Genes involved in Metabolism of nucleotides
3.8 68.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
3.7 85.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
3.6 36.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
3.6 36.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
3.6 251.0 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
3.6 74.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
3.5 14.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
3.5 80.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
3.4 20.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
3.4 61.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
3.3 26.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
3.3 23.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
3.1 144.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
3.1 9.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
3.1 3.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
3.0 127.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
3.0 32.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
3.0 76.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
2.9 26.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
2.8 69.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
2.8 82.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
2.7 155.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
2.7 32.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
2.7 13.4 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
2.7 152.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
2.7 37.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
2.7 8.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
2.6 287.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
2.6 41.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
2.5 42.2 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
2.4 59.3 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
2.3 29.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
2.2 33.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.2 45.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
2.1 55.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.9 76.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
1.8 38.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
1.8 20.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.7 27.8 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
1.7 34.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
1.7 15.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
1.6 8.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.6 11.2 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
1.6 68.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
1.6 84.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
1.5 60.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
1.5 90.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
1.4 208.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
1.4 66.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.3 18.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.3 97.0 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
1.3 6.4 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
1.3 1.3 REACTOME SIGNALING BY INSULIN RECEPTOR Genes involved in Signaling by Insulin receptor
1.2 12.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
1.2 56.3 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
1.2 18.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.1 3.4 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
1.1 25.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
1.1 26.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.0 2.1 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
1.0 39.6 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
1.0 6.7 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
1.0 17.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.9 16.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.8 12.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.7 11.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.7 2.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.7 12.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.7 4.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.6 20.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.5 5.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.5 31.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.3 5.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.3 5.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.3 6.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 0.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 2.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 7.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 4.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 0.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 8.2 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.2 21.9 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.2 8.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 1.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 4.4 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1 0.4 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)