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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ELF3_EHF

Z-value: 1.66

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Transcription factors associated with ELF3_EHF

Gene Symbol Gene ID Gene Info
ELF3
ENSG00000163435.11 E74 like ETS transcription factor 3
EHF
ENSG00000135373.8 ETS homologous factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ELF3hg19_v2_chr1_+_201979645_2019797210.307.9e-06Click!
EHFhg19_v2_chr11_+_34642656_346426820.136.0e-02Click!

Activity profile of ELF3_EHF motif

Sorted Z-values of ELF3_EHF motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_48532019 34.34 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr14_+_69865401 29.07 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9
solute carrier family 39, member 9
chr1_+_169337172 25.55 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1
basic leucine zipper nuclear factor 1
chr3_+_57541975 22.12 ENST00000487257.1
ENST00000311180.8
PDE12
phosphodiesterase 12
chr1_+_156698234 21.97 ENST00000368218.4
ENST00000368216.4
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr6_+_111580508 21.48 ENST00000368847.4
KIAA1919
KIAA1919
chr15_+_45879534 21.46 ENST00000564080.1
ENST00000562384.1
ENST00000569076.1
ENST00000566753.1
RP11-96O20.4
BLOC1S6
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr19_+_58694396 20.47 ENST00000326804.4
ENST00000345813.3
ENST00000424679.2
ZNF274
zinc finger protein 274
chr19_-_56632592 20.25 ENST00000587279.1
ENST00000270459.3
ZNF787
zinc finger protein 787
chr15_+_45879321 20.12 ENST00000220531.3
ENST00000567461.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr16_-_25122785 20.11 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1
RP11-449H11.1
chr11_+_70244510 20.04 ENST00000346329.3
ENST00000301843.8
ENST00000376561.3
CTTN
cortactin
chr19_+_52901094 19.19 ENST00000391788.2
ENST00000436397.1
ENST00000391787.2
ENST00000360465.3
ENST00000494167.2
ENST00000493272.1
ZNF528
zinc finger protein 528
chr19_-_53289995 19.01 ENST00000338230.3
ZNF600
zinc finger protein 600
chrX_+_70586140 18.76 ENST00000276072.3
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr9_-_86571628 18.74 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr19_+_16296191 17.21 ENST00000589852.1
ENST00000263384.7
ENST00000588367.1
ENST00000587351.1
FAM32A
family with sequence similarity 32, member A
chr12_+_57914742 17.12 ENST00000551351.1
MBD6
methyl-CpG binding domain protein 6
chr19_+_53836985 17.07 ENST00000601857.1
ENST00000595091.1
ENST00000458035.1
ZNF845
zinc finger protein 845
chr19_+_47759716 16.67 ENST00000221922.6
CCDC9
coiled-coil domain containing 9
chr12_+_108908962 16.46 ENST00000552695.1
ENST00000552758.1
ENST00000361549.2
FICD
FIC domain containing
chr6_+_36853607 16.30 ENST00000480824.2
ENST00000355190.3
ENST00000373685.1
C6orf89
chromosome 6 open reading frame 89
chr11_+_124492749 16.16 ENST00000531667.1
ENST00000441174.3
ENST00000375005.4
TBRG1
transforming growth factor beta regulator 1
chr16_+_19729586 16.06 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQCK
IQ motif containing K
chr17_+_42264322 15.92 ENST00000446571.3
ENST00000357984.3
ENST00000538716.2
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr2_+_113342163 15.89 ENST00000409719.1
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr18_+_74240610 15.79 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
LINC00908
long intergenic non-protein coding RNA 908
chr16_-_31085514 15.46 ENST00000300849.4
ZNF668
zinc finger protein 668
chr17_+_32582293 15.36 ENST00000580907.1
ENST00000225831.4
CCL2
chemokine (C-C motif) ligand 2
chr10_+_81838792 15.31 ENST00000372273.3
TMEM254
transmembrane protein 254
chr3_-_138763734 15.20 ENST00000413199.1
ENST00000502927.2
PRR23C
proline rich 23C
chr1_-_204380919 15.18 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr5_-_93447333 14.56 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr1_+_156698708 14.25 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr11_+_2421718 13.98 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4
tumor suppressing subtransferable candidate 4
chr2_-_175351744 13.97 ENST00000295500.4
ENST00000392552.2
ENST00000392551.2
GPR155
G protein-coupled receptor 155
chr17_+_42264395 13.93 ENST00000587989.1
ENST00000590235.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr16_+_77224732 13.93 ENST00000569610.1
ENST00000248248.3
ENST00000567291.1
ENST00000320859.6
ENST00000563612.1
ENST00000563279.1
MON1B
MON1 secretory trafficking family member B
chr14_+_100842735 13.90 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WDR25
WD repeat domain 25
chr7_-_99149715 13.82 ENST00000449309.1
FAM200A
family with sequence similarity 200, member A
chr6_+_31620191 13.75 ENST00000375918.2
ENST00000375920.4
APOM
apolipoprotein M
chrX_+_70586082 13.71 ENST00000373790.4
ENST00000449580.1
ENST00000423759.1
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chrX_+_129473859 13.68 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr6_+_126240442 13.64 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr15_+_45879779 13.36 ENST00000566801.1
ENST00000568816.1
ENST00000565323.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr16_+_4784458 13.29 ENST00000590191.1
C16orf71
chromosome 16 open reading frame 71
chr1_-_157108266 13.26 ENST00000326786.4
ETV3
ets variant 3
chr17_-_79269067 13.25 ENST00000288439.5
ENST00000374759.3
SLC38A10
solute carrier family 38, member 10
chr17_-_38256973 13.24 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr1_+_52870227 12.99 ENST00000257181.9
PRPF38A
pre-mRNA processing factor 38A
chr12_-_57914275 12.94 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DDIT3
DNA-damage-inducible transcript 3
chr16_+_31085714 12.88 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646
zinc finger protein 646
chr3_-_28390581 12.88 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr12_-_12509929 12.79 ENST00000381800.2
LOH12CR2
loss of heterozygosity, 12, chromosomal region 2 (non-protein coding)
chr20_-_48532046 12.74 ENST00000543716.1
SPATA2
spermatogenesis associated 2
chr11_-_64885111 12.54 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr12_-_123215306 12.54 ENST00000356987.2
ENST00000436083.2
HCAR1
hydroxycarboxylic acid receptor 1
chr17_+_40118805 12.52 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr6_-_159420780 12.29 ENST00000449822.1
RSPH3
radial spoke 3 homolog (Chlamydomonas)
chr2_-_10830093 12.25 ENST00000381685.5
ENST00000345985.3
ENST00000542668.1
ENST00000538384.1
NOL10
nucleolar protein 10
chr7_-_35734730 12.00 ENST00000396081.1
ENST00000311350.3
HERPUD2
HERPUD family member 2
chr11_-_104035088 11.97 ENST00000302251.5
PDGFD
platelet derived growth factor D
chr14_+_74417192 11.94 ENST00000554320.1
COQ6
coenzyme Q6 monooxygenase
chr3_-_155461515 11.62 ENST00000399242.2
AC104472.1
CDNA FLJ26134 fis, clone TMS03713; Uncharacterized protein
chr5_-_43412418 11.62 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr19_-_12662240 11.52 ENST00000416136.1
ENST00000428311.1
ZNF564
ZNF709
zinc finger protein 564
ZNF709
chr18_-_52989217 11.50 ENST00000570287.2
TCF4
transcription factor 4
chr4_-_492891 11.42 ENST00000338977.5
ENST00000511833.2
ZNF721
zinc finger protein 721
chr2_-_241500447 11.23 ENST00000536462.1
ENST00000405002.1
ENST00000441168.1
ENST00000403283.1
ANKMY1
ankyrin repeat and MYND domain containing 1
chr17_-_33905521 11.17 ENST00000225873.4
PEX12
peroxisomal biogenesis factor 12
chr17_+_40118759 11.01 ENST00000393892.3
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr7_+_149597 10.86 ENST00000484550.1
ENST00000479592.1
ENST00000471299.1
AC093627.10
AC093627.10
chr7_+_86781847 10.79 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
DMTF1
cyclin D binding myb-like transcription factor 1
chr11_+_61891445 10.75 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP
inner centromere protein antigens 135/155kDa
chr4_+_166128735 10.59 ENST00000226725.6
KLHL2
kelch-like family member 2
chr7_+_86781677 10.59 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
DMTF1
cyclin D binding myb-like transcription factor 1
chr3_+_15468862 10.49 ENST00000396842.2
EAF1
ELL associated factor 1
chr17_+_47865917 10.44 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
KAT7
K(lysine) acetyltransferase 7
chr19_-_36870087 10.41 ENST00000270001.7
ZFP14
ZFP14 zinc finger protein
chr5_-_130970723 10.20 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr2_-_69870747 10.02 ENST00000409068.1
AAK1
AP2 associated kinase 1
chr10_-_50747064 9.99 ENST00000355832.5
ENST00000603152.1
ENST00000447839.2
ERCC6
PGBD3
ERCC6-PGBD3
excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
ERCC6-PGBD3 readthrough
chrX_+_47092314 9.96 ENST00000218348.3
USP11
ubiquitin specific peptidase 11
chr1_+_151043070 9.95 ENST00000368918.3
ENST00000368917.1
GABPB2
GA binding protein transcription factor, beta subunit 2
chr19_+_52772832 9.95 ENST00000593703.1
ENST00000601711.1
ENST00000599581.1
ZNF766
zinc finger protein 766
chr1_+_197170592 9.85 ENST00000535699.1
CRB1
crumbs homolog 1 (Drosophila)
chr3_+_130745688 9.77 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11
NIMA-related kinase 11
chr15_+_23810853 9.70 ENST00000568252.1
MKRN3
makorin ring finger protein 3
chr5_-_79287060 9.70 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
MTX3
metaxin 3
chr6_-_159421198 9.70 ENST00000252655.1
ENST00000297262.3
ENST00000367069.2
RSPH3
radial spoke 3 homolog (Chlamydomonas)
chr15_-_74284613 9.57 ENST00000316911.6
ENST00000564777.1
ENST00000566081.1
ENST00000316900.5
STOML1
stomatin (EPB72)-like 1
chr2_-_85555086 9.51 ENST00000444342.2
ENST00000409232.3
ENST00000409015.1
TGOLN2
trans-golgi network protein 2
chr19_-_45004556 9.47 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180
zinc finger protein 180
chr1_+_204797749 9.45 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
NFASC
neurofascin
chr11_-_62389449 9.34 ENST00000534026.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr15_-_90892669 9.27 ENST00000412799.2
GABARAPL3
GABA(A) receptors associated protein like 3, pseudogene
chr10_-_15902449 9.26 ENST00000277632.3
FAM188A
family with sequence similarity 188, member A
chr17_-_42580738 9.16 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
GPATCH8
G patch domain containing 8
chr19_-_53757941 9.13 ENST00000594517.1
ENST00000601413.1
ENST00000594681.1
ZNF677
zinc finger protein 677
chr17_+_74733744 9.05 ENST00000586689.1
ENST00000587661.1
ENST00000593181.1
ENST00000336509.4
ENST00000355954.3
MFSD11
major facilitator superfamily domain containing 11
chr3_-_15469006 8.97 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
METTL6
methyltransferase like 6
chr3_-_137893721 8.95 ENST00000505015.2
ENST00000260803.4
DBR1
debranching RNA lariats 1
chr8_-_134309823 8.92 ENST00000414097.2
NDRG1
N-myc downstream regulated 1
chr1_+_10003486 8.89 ENST00000403197.1
ENST00000377205.1
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr1_+_151254738 8.87 ENST00000336715.6
ENST00000324048.5
ENST00000368879.2
ZNF687
zinc finger protein 687
chr7_+_66205643 8.77 ENST00000380828.2
ENST00000510829.2
KCTD7
potassium channel tetramerization domain containing 7
chr19_+_52772821 8.71 ENST00000439461.1
ZNF766
zinc finger protein 766
chr7_-_150020578 8.68 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr5_+_140864649 8.54 ENST00000306593.1
PCDHGC4
protocadherin gamma subfamily C, 4
chr5_+_137801160 8.53 ENST00000239938.4
EGR1
early growth response 1
chr1_+_24742264 8.50 ENST00000374399.4
ENST00000003912.3
ENST00000358028.4
ENST00000339255.2
NIPAL3
NIPA-like domain containing 3
chr15_-_64648273 8.49 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
CSNK1G1
casein kinase 1, gamma 1
chr1_-_28969517 8.43 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr2_-_69870835 8.41 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr3_+_130745769 8.39 ENST00000412440.2
NEK11
NIMA-related kinase 11
chr8_+_144816303 8.35 ENST00000533004.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr19_-_1174226 8.30 ENST00000587024.1
ENST00000361757.3
SBNO2
strawberry notch homolog 2 (Drosophila)
chr14_+_74416989 8.29 ENST00000334571.2
ENST00000554920.1
COQ6
coenzyme Q6 monooxygenase
chr22_-_38245304 8.24 ENST00000609454.1
ANKRD54
ankyrin repeat domain 54
chr17_+_34958001 8.13 ENST00000250156.7
MRM1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr2_+_54198210 8.12 ENST00000607452.1
ENST00000422521.2
ACYP2
acylphosphatase 2, muscle type
chr2_+_166428839 8.04 ENST00000342316.4
CSRNP3
cysteine-serine-rich nuclear protein 3
chr12_-_66524482 8.02 ENST00000446587.2
ENST00000266604.2
LLPH
LLP homolog, long-term synaptic facilitation (Aplysia)
chr5_-_35230434 7.98 ENST00000504500.1
PRLR
prolactin receptor
chr8_-_134309335 7.92 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr12_-_118796910 7.88 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr1_+_204485503 7.84 ENST00000367182.3
ENST00000507825.2
MDM4
Mdm4 p53 binding protein homolog (mouse)
chr19_+_10541462 7.83 ENST00000293683.5
PDE4A
phosphodiesterase 4A, cAMP-specific
chr2_+_17935383 7.79 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1
GEN1 Holliday junction 5' flap endonuclease
chr5_+_54455946 7.79 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chrX_+_54947229 7.77 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr19_-_53696587 7.77 ENST00000396424.3
ENST00000600412.1
ZNF665
zinc finger protein 665
chr1_+_18081804 7.75 ENST00000375406.1
ACTL8
actin-like 8
chr8_-_67341208 7.74 ENST00000499642.1
RP11-346I3.4
RP11-346I3.4
chr8_+_100025476 7.62 ENST00000355155.1
ENST00000357162.2
ENST00000358544.2
ENST00000395996.1
ENST00000441350.2
VPS13B
vacuolar protein sorting 13 homolog B (yeast)
chr22_+_22020273 7.59 ENST00000412327.1
ENST00000335025.8
ENST00000398831.3
ENST00000492445.2
ENST00000458567.1
ENST00000406385.1
PPIL2
peptidylprolyl isomerase (cyclophilin)-like 2
chr5_-_443239 7.59 ENST00000408966.2
C5orf55
chromosome 5 open reading frame 55
chr10_+_102672712 7.57 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A
family with sequence similarity 178, member A
chr6_-_99873145 7.50 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr16_+_69166418 7.44 ENST00000314423.7
ENST00000562237.1
ENST00000567460.1
ENST00000566227.1
ENST00000352319.4
ENST00000563094.1
CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr6_-_11779840 7.41 ENST00000506810.1
ADTRP
androgen-dependent TFPI-regulating protein
chr5_-_131892501 7.35 ENST00000450655.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr14_+_93389425 7.34 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chrX_+_114827818 7.32 ENST00000420625.2
PLS3
plastin 3
chr9_+_71944241 7.31 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr5_+_130506475 7.30 ENST00000379380.4
LYRM7
LYR motif containing 7
chr17_+_4843654 7.24 ENST00000575111.1
RNF167
ring finger protein 167
chr9_+_37753795 7.16 ENST00000377753.2
ENST00000537911.1
ENST00000377754.2
ENST00000297994.3
TRMT10B
tRNA methyltransferase 10 homolog B (S. cerevisiae)
chr15_-_83378611 7.04 ENST00000542200.1
AP3B2
adaptor-related protein complex 3, beta 2 subunit
chr11_-_119993979 7.02 ENST00000524816.3
ENST00000525327.1
TRIM29
tripartite motif containing 29
chr7_+_142829162 7.02 ENST00000291009.3
PIP
prolactin-induced protein
chr11_-_61129335 7.00 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
CYB561A3
cytochrome b561 family, member A3
chr18_-_52989525 6.99 ENST00000457482.3
TCF4
transcription factor 4
chr4_+_2813946 6.98 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr16_+_2587998 6.96 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr11_-_104034827 6.94 ENST00000393158.2
PDGFD
platelet derived growth factor D
chr14_-_31926701 6.92 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr19_-_4723761 6.91 ENST00000597849.1
ENST00000598800.1
ENST00000602161.1
ENST00000597726.1
ENST00000601130.1
ENST00000262960.9
DPP9
dipeptidyl-peptidase 9
chr19_-_53758094 6.85 ENST00000601828.1
ENST00000598513.1
ENST00000599012.1
ENST00000333952.4
ENST00000598806.1
ZNF677
zinc finger protein 677
chr20_+_54967409 6.85 ENST00000415828.1
ENST00000217109.4
ENST00000428552.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr1_-_154946825 6.85 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr19_-_37701386 6.83 ENST00000527838.1
ENST00000591492.1
ENST00000532828.2
ZNF585B
zinc finger protein 585B
chr13_-_33760216 6.79 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr20_-_18774614 6.77 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr18_+_43246028 6.75 ENST00000589658.1
SLC14A2
solute carrier family 14 (urea transporter), member 2
chr5_-_127418755 6.70 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3
CTC-228N24.3
chr17_-_37844267 6.68 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
PGAP3
post-GPI attachment to proteins 3
chr4_+_153701081 6.68 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1
ADP-ribosylation factor interacting protein 1
chr2_-_224467093 6.68 ENST00000305409.2
SCG2
secretogranin II
chr11_+_64008525 6.66 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr15_-_102192567 6.66 ENST00000333202.3
ENST00000428002.2
ENST00000559107.1
ENST00000347970.3
TM2D3
TM2 domain containing 3
chr10_+_95326416 6.63 ENST00000371481.4
ENST00000371483.4
ENST00000604414.1
FFAR4
free fatty acid receptor 4
chr16_+_2588012 6.53 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr2_+_138721850 6.48 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr10_+_101089107 6.47 ENST00000446890.1
ENST00000370528.3
CNNM1
cyclin M1
chrX_+_57618269 6.40 ENST00000374888.1
ZXDB
zinc finger, X-linked, duplicated B
chr15_+_43985725 6.38 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chrX_-_2418596 6.37 ENST00000381218.3
ZBED1
zinc finger, BED-type containing 1
chrX_-_102348017 6.36 ENST00000425644.1
ENST00000395065.3
ENST00000425463.2
NXF3
nuclear RNA export factor 3
chr16_+_1662326 6.35 ENST00000397412.3
CRAMP1L
Crm, cramped-like (Drosophila)
chr5_-_137090028 6.35 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr16_+_2587965 6.28 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr1_-_47779762 6.27 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
STIL
SCL/TAL1 interrupting locus
chr4_+_156588350 6.25 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr5_+_140044261 6.24 ENST00000358337.5
WDR55
WD repeat domain 55
chr10_+_81838411 6.22 ENST00000372281.3
ENST00000372277.3
ENST00000372275.1
ENST00000372274.1
TMEM254
transmembrane protein 254
chr2_-_152830479 6.22 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr7_+_108210012 6.20 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr17_-_18218237 6.18 ENST00000542570.1
TOP3A
topoisomerase (DNA) III alpha
chr3_-_93781750 6.11 ENST00000314636.2
DHFRL1
dihydrofolate reductase-like 1
chrX_+_16737718 6.03 ENST00000380155.3
SYAP1
synapse associated protein 1
chr17_+_73975292 6.00 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1
TEN1 CST complex subunit
chrX_-_7895755 6.00 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
PNPLA4
patatin-like phospholipase domain containing 4
chr16_+_4784273 5.99 ENST00000299320.5
ENST00000586724.1
C16orf71
chromosome 16 open reading frame 71
chr14_+_85996471 5.98 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr17_+_48610074 5.97 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr16_+_30710462 5.94 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr5_+_149737202 5.90 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1
Treacher Collins-Franceschetti syndrome 1
chr11_-_62389621 5.90 ENST00000531383.1
ENST00000265471.5
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr15_+_93749295 5.85 ENST00000599897.1
AC112693.2
AC112693.2

Network of associatons between targets according to the STRING database.

First level regulatory network of ELF3_EHF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 32.5 GO:0036369 transcription factor catabolic process(GO:0036369)
6.3 18.9 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
5.1 15.4 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
4.4 13.2 GO:0060086 circadian temperature homeostasis(GO:0060086)
4.1 8.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
4.0 55.3 GO:0016081 synaptic vesicle docking(GO:0016081)
3.5 13.9 GO:0019086 late viral transcription(GO:0019086)
3.5 10.4 GO:0072716 response to actinomycin D(GO:0072716)
3.4 13.8 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
3.3 6.7 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) regulation of actin nucleation(GO:0051125)
3.2 12.9 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
3.1 3.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
2.9 5.8 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
2.8 8.5 GO:0050720 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759) regulation of progesterone biosynthetic process(GO:2000182)
2.7 8.1 GO:1990502 dense core granule maturation(GO:1990502)
2.6 7.8 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
2.5 7.5 GO:0034227 tRNA thio-modification(GO:0034227)
2.4 7.3 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
2.4 7.3 GO:1901899 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
2.3 11.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
2.3 30.0 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
2.2 24.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
2.1 12.6 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
2.1 8.3 GO:0044375 regulation of peroxisome size(GO:0044375)
2.0 16.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
2.0 21.9 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
2.0 6.0 GO:0097359 UDP-glucosylation(GO:0097359)
2.0 19.8 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.9 15.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
1.9 14.9 GO:0015693 magnesium ion transport(GO:0015693)
1.8 5.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.8 5.5 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
1.8 5.4 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
1.8 35.7 GO:0031167 rRNA methylation(GO:0031167)
1.8 10.6 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
1.7 5.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
1.7 5.1 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
1.7 9.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.6 4.9 GO:2000870 regulation of progesterone secretion(GO:2000870)
1.6 4.9 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
1.6 30.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.6 6.3 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
1.6 4.7 GO:0006014 D-ribose metabolic process(GO:0006014)
1.6 4.7 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.6 9.3 GO:0001692 histamine metabolic process(GO:0001692)
1.5 4.6 GO:0019482 beta-alanine metabolic process(GO:0019482)
1.5 9.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
1.5 6.1 GO:0001743 optic placode formation(GO:0001743)
1.5 4.5 GO:0043400 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
1.4 10.0 GO:0007256 activation of JNKK activity(GO:0007256)
1.4 7.1 GO:2000843 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
1.4 2.8 GO:0034472 snRNA 3'-end processing(GO:0034472)
1.4 23.6 GO:0006265 DNA topological change(GO:0006265)
1.4 8.3 GO:0071105 response to interleukin-11(GO:0071105)
1.4 5.5 GO:0018094 protein polyglycylation(GO:0018094)
1.4 4.1 GO:0070781 response to biotin(GO:0070781)
1.4 6.8 GO:0071918 urea transmembrane transport(GO:0071918)
1.3 8.0 GO:0038161 prolactin signaling pathway(GO:0038161)
1.3 3.9 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
1.3 15.2 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
1.3 3.8 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
1.3 3.8 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
1.3 3.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.2 5.0 GO:0035962 response to interleukin-13(GO:0035962)
1.2 5.0 GO:0009233 menaquinone metabolic process(GO:0009233) menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
1.2 6.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
1.2 3.7 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle recycling(GO:1903423)
1.2 7.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
1.2 5.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125) minus-end-directed organelle transport along microtubule(GO:0072385)
1.1 6.9 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
1.1 3.3 GO:0071284 cellular response to lead ion(GO:0071284)
1.1 3.2 GO:0061055 myotome development(GO:0061055)
1.0 6.3 GO:0033504 floor plate development(GO:0033504)
1.0 13.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
1.0 3.1 GO:0072092 ureteric bud invasion(GO:0072092)
1.0 4.0 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
1.0 25.0 GO:0006829 zinc II ion transport(GO:0006829)
1.0 23.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
1.0 8.9 GO:0006531 aspartate metabolic process(GO:0006531)
1.0 4.9 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
1.0 1.9 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
1.0 4.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
1.0 4.8 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.0 2.9 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.9 3.7 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.9 5.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.9 2.6 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.9 2.6 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.9 9.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.9 2.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.9 3.4 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.9 11.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.8 13.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.8 9.2 GO:0006600 creatine metabolic process(GO:0006600)
0.8 9.9 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.8 4.7 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.8 11.0 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.8 8.7 GO:0015886 heme transport(GO:0015886)
0.8 4.7 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.8 12.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.8 6.2 GO:0006013 mannose metabolic process(GO:0006013)
0.8 11.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.8 2.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.8 4.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.7 2.2 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.7 5.2 GO:1903232 melanosome assembly(GO:1903232)
0.7 4.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.7 0.7 GO:0065001 specification of axis polarity(GO:0065001)
0.7 7.8 GO:0045023 G0 to G1 transition(GO:0045023)
0.7 2.1 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.7 3.6 GO:0010966 regulation of phosphate transport(GO:0010966)
0.7 2.8 GO:0042335 cuticle development(GO:0042335)
0.7 5.6 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.7 4.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.7 3.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.7 4.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.7 2.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.7 32.8 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.7 17.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.7 3.4 GO:0030047 actin modification(GO:0030047)
0.7 2.0 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.7 5.4 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.7 2.7 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.7 3.3 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.7 2.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.7 2.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.7 15.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.6 3.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.6 4.5 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.6 1.9 GO:0051697 protein delipidation(GO:0051697)
0.6 6.9 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.6 4.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.6 17.3 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.6 1.2 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.6 3.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.6 1.8 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.6 3.5 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.6 4.1 GO:0006477 protein sulfation(GO:0006477)
0.6 10.5 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.6 5.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.6 1.7 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.6 4.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.6 1.7 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.6 12.4 GO:0030488 tRNA methylation(GO:0030488)
0.6 3.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.6 1.7 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.5 15.8 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.5 1.6 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.5 2.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.5 2.1 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.5 2.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.5 4.2 GO:0015705 iodide transport(GO:0015705)
0.5 1.5 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.5 3.6 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.5 12.7 GO:0032607 interferon-alpha production(GO:0032607)
0.5 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.5 1.0 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.5 2.9 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.5 7.3 GO:0051639 actin filament network formation(GO:0051639)
0.5 0.5 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.5 1.9 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.5 1.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.5 6.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.5 1.4 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.5 2.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.5 3.7 GO:0031642 negative regulation of myelination(GO:0031642)
0.5 1.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.5 3.2 GO:0016559 peroxisome fission(GO:0016559)
0.5 5.0 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.4 1.3 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.4 3.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.4 2.6 GO:0060011 sperm ejaculation(GO:0042713) Sertoli cell proliferation(GO:0060011)
0.4 9.8 GO:0034389 lipid particle organization(GO:0034389)
0.4 1.7 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.4 2.5 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.4 1.3 GO:0009078 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.4 15.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.4 2.5 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.4 16.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.4 4.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.4 2.9 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.4 2.0 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.4 2.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 4.9 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.4 1.2 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.4 5.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.4 2.0 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.4 6.8 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.4 5.9 GO:0014029 neural crest formation(GO:0014029)
0.4 0.8 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.4 6.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.4 3.1 GO:0051601 exocyst localization(GO:0051601)
0.4 1.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.4 1.9 GO:0006449 regulation of translational termination(GO:0006449)
0.4 2.6 GO:0035865 cellular response to potassium ion(GO:0035865)
0.4 5.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.4 2.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 1.1 GO:0071529 cementum mineralization(GO:0071529)
0.4 8.5 GO:0009435 NAD biosynthetic process(GO:0009435)
0.4 13.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.4 2.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.3 2.4 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.3 2.8 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.3 5.8 GO:0042737 drug catabolic process(GO:0042737)
0.3 4.8 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.3 5.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.3 3.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.3 4.3 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.3 2.6 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 1.9 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.3 4.1 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 10.1 GO:0006400 tRNA modification(GO:0006400)
0.3 4.4 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.3 3.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.3 6.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.3 0.6 GO:0097152 mesenchymal cell apoptotic process(GO:0097152)
0.3 2.1 GO:0071158 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) positive regulation of cell cycle arrest(GO:0071158)
0.3 13.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.3 14.2 GO:0007050 cell cycle arrest(GO:0007050)
0.3 2.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.3 2.9 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.3 0.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.3 6.9 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.3 1.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 1.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3 1.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.3 2.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.3 2.7 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.3 3.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.3 3.2 GO:0035878 nail development(GO:0035878)
0.3 0.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.3 4.0 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.3 20.9 GO:0030574 collagen catabolic process(GO:0030574)
0.3 3.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.3 2.3 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.3 3.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.3 12.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.3 0.8 GO:0035811 negative regulation of urine volume(GO:0035811)
0.3 9.9 GO:0042073 intraciliary transport(GO:0042073)
0.3 1.3 GO:0046968 peptide antigen transport(GO:0046968)
0.3 2.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.3 1.0 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.2 2.5 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.2 3.7 GO:0034453 microtubule anchoring(GO:0034453)
0.2 5.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 3.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 1.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 0.7 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.2 2.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 1.6 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.2 5.2 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.2 2.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 5.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.2 13.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 0.9 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.2 1.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.2 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 4.3 GO:0036010 protein localization to endosome(GO:0036010)
0.2 3.8 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 4.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 2.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.2 1.7 GO:0016926 protein desumoylation(GO:0016926)
0.2 2.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 1.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 3.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 3.0 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.2 6.5 GO:0018149 peptide cross-linking(GO:0018149)
0.2 2.2 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.2 2.0 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 0.6 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.2 1.8 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.2 5.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.2 1.9 GO:0016322 neuron remodeling(GO:0016322)
0.2 0.6 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 1.7 GO:0001510 RNA methylation(GO:0001510)
0.2 0.6 GO:0071258 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.2 0.8 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 1.9 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.2 0.9 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.2 1.9 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.2 1.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.2 3.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 8.3 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.2 0.9 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of lung blood pressure(GO:0061767) positive regulation of extracellular matrix assembly(GO:1901203) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.2 8.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 1.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 0.4 GO:2000232 regulation of ribosome biogenesis(GO:0090069) regulation of rRNA processing(GO:2000232)
0.2 1.7 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.2 6.7 GO:0097484 dendrite extension(GO:0097484)
0.2 4.3 GO:0016925 protein sumoylation(GO:0016925)
0.2 0.8 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) negative regulation of sperm motility(GO:1901318) positive regulation of serine-type peptidase activity(GO:1902573)
0.2 5.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.2 0.5 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.2 1.6 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2 1.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 2.2 GO:0015671 oxygen transport(GO:0015671)
0.2 3.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.9 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 2.7 GO:0060271 cilium morphogenesis(GO:0060271)
0.2 0.6 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 1.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 1.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 20.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 4.5 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.7 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 1.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 1.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.4 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.2 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.1 3.2 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 2.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.6 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154) regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 5.4 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 5.2 GO:0031529 ruffle organization(GO:0031529)
0.1 5.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 2.7 GO:0060325 face morphogenesis(GO:0060325)
0.1 3.9 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 0.3 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 4.6 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 1.7 GO:0016264 gap junction assembly(GO:0016264)
0.1 2.3 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.1 1.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 3.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.9 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.9 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.1 GO:0042940 D-amino acid transport(GO:0042940)
0.1 4.0 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 1.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 4.8 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.7 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 1.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 5.1 GO:0031016 pancreas development(GO:0031016)
0.1 3.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 3.0 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 1.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 3.0 GO:0003091 renal water homeostasis(GO:0003091)
0.1 3.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 3.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 4.9 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.1 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 1.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 1.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 3.6 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.1 1.1 GO:0007220 Notch receptor processing(GO:0007220)
0.1 1.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 1.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.0 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 0.9 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 1.1 GO:0042220 response to cocaine(GO:0042220)
0.1 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 6.5 GO:0007030 Golgi organization(GO:0007030)
0.1 1.1 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 0.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.1 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.1 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 2.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 1.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0002407 dendritic cell chemotaxis(GO:0002407)
0.0 0.7 GO:0010506 regulation of autophagy(GO:0010506)
0.0 5.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 3.8 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.2 GO:0021539 subthalamus development(GO:0021539)
0.0 18.0 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.2 GO:0002396 MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399)
0.0 0.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 2.3 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 2.9 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.9 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.9 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 2.3 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 3.5 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 1.3 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 4.6 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.7 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 1.5 GO:0032259 methylation(GO:0032259)
0.0 1.1 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 3.6 GO:0048705 skeletal system morphogenesis(GO:0048705)
0.0 0.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.6 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.8 GO:1990748 detoxification(GO:0098754) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.3 GO:0002251 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:0045730 respiratory burst(GO:0045730)
0.0 1.0 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 1.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.3 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.4 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
4.3 12.9 GO:1990622 CHOP-ATF3 complex(GO:1990622)
3.2 57.3 GO:0031083 BLOC-1 complex(GO:0031083)
2.4 9.4 GO:0097454 Schwann cell microvillus(GO:0097454)
2.2 10.8 GO:0000801 central element(GO:0000801)
1.8 11.0 GO:0032807 DNA ligase IV complex(GO:0032807)
1.8 21.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
1.7 5.1 GO:0061673 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
1.6 4.9 GO:0019034 viral replication complex(GO:0019034)
1.6 6.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
1.4 7.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
1.4 4.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
1.4 4.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.3 6.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
1.2 3.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
1.2 3.5 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
1.1 6.6 GO:0030991 intraciliary transport particle A(GO:0030991)
1.0 6.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.0 18.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.0 13.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.0 5.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.9 2.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.9 4.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.8 21.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.8 3.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.7 4.5 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.7 9.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.7 0.7 GO:1990769 proximal neuron projection(GO:1990769)
0.7 2.7 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.7 2.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.6 2.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.6 12.2 GO:0031045 dense core granule(GO:0031045)
0.6 7.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.6 3.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.6 2.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.6 64.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.6 2.8 GO:0070847 core mediator complex(GO:0070847)
0.5 3.2 GO:0061689 tricellular tight junction(GO:0061689)
0.5 7.3 GO:0042583 chromaffin granule(GO:0042583)
0.5 4.7 GO:0033391 chromatoid body(GO:0033391)
0.5 10.3 GO:0044447 axoneme part(GO:0044447)
0.5 3.6 GO:0061700 GATOR2 complex(GO:0061700)
0.5 2.4 GO:0060091 kinocilium(GO:0060091)
0.5 12.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.5 2.4 GO:0036128 CatSper complex(GO:0036128)
0.5 11.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 6.7 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.4 3.0 GO:0097165 nuclear stress granule(GO:0097165)
0.4 12.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.4 1.9 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.4 2.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.4 2.6 GO:0016272 prefoldin complex(GO:0016272)
0.4 56.2 GO:0001650 fibrillar center(GO:0001650)
0.4 8.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 4.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 1.4 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3 5.5 GO:0005652 nuclear lamina(GO:0005652)
0.3 4.5 GO:0000124 SAGA complex(GO:0000124)
0.3 9.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.3 19.9 GO:0005801 cis-Golgi network(GO:0005801)
0.3 3.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 4.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 3.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.3 4.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 1.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 6.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 3.9 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.3 5.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.3 2.8 GO:0032039 integrator complex(GO:0032039)
0.3 35.4 GO:0005796 Golgi lumen(GO:0005796)
0.3 14.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 4.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.3 2.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 8.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 3.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 6.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 19.3 GO:0005902 microvillus(GO:0005902)
0.3 4.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 3.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 7.0 GO:0032040 small-subunit processome(GO:0032040)
0.2 7.4 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.2 1.2 GO:0031905 early endosome lumen(GO:0031905)
0.2 1.1 GO:0097452 GAIT complex(GO:0097452)
0.2 1.3 GO:0000322 storage vacuole(GO:0000322)
0.2 1.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 4.9 GO:0032420 stereocilium(GO:0032420)
0.2 11.0 GO:0001533 cornified envelope(GO:0001533)
0.2 1.0 GO:0036019 endolysosome(GO:0036019)
0.2 8.2 GO:0031904 endosome lumen(GO:0031904)
0.2 2.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 15.5 GO:0005811 lipid particle(GO:0005811)
0.2 12.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 2.0 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 6.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 5.7 GO:0016592 mediator complex(GO:0016592)
0.2 1.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 1.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 5.6 GO:0030673 axolemma(GO:0030673)
0.2 2.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 3.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 8.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 2.6 GO:0070069 cytochrome complex(GO:0070069)
0.2 1.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.2 11.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 4.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 1.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 1.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 5.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 14.3 GO:0032432 actin filament bundle(GO:0032432)
0.1 1.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 3.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 36.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 1.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.4 GO:0005869 dynactin complex(GO:0005869)
0.1 3.4 GO:0005776 autophagosome(GO:0005776)
0.1 0.3 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.5 GO:0033263 CORVET complex(GO:0033263)
0.1 6.7 GO:0036064 ciliary basal body(GO:0036064)
0.1 6.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.4 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837) postsynaptic endosome(GO:0098845)
0.1 5.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 6.2 GO:0043195 terminal bouton(GO:0043195)
0.1 2.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.6 GO:0000145 exocyst(GO:0000145)
0.1 1.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 3.7 GO:0043679 axon terminus(GO:0043679)
0.1 19.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 3.4 GO:0098858 actin-based cell projection(GO:0098858)
0.1 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 9.4 GO:0032993 protein-DNA complex(GO:0032993)
0.1 1.8 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.0 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 2.2 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.1 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.0 4.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 10.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.7 GO:0030424 axon(GO:0030424)
0.0 2.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 6.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 139.7 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.0 2.7 GO:0030426 growth cone(GO:0030426)
0.0 2.2 GO:0019867 outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 0.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.2 GO:0043204 perikaryon(GO:0043204)
0.0 2.9 GO:0001726 ruffle(GO:0001726)
0.0 26.2 GO:0005615 extracellular space(GO:0005615)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0031514 motile cilium(GO:0031514)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 36.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
6.6 19.8 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
6.3 31.5 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
5.1 15.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
5.1 15.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
4.5 27.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
3.1 9.4 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
3.0 8.9 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
2.7 8.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
2.4 7.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
2.1 6.4 GO:0015439 heme-transporting ATPase activity(GO:0015439)
2.0 6.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
2.0 21.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.0 3.9 GO:0020037 heme binding(GO:0020037)
1.9 7.8 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.8 3.6 GO:0034511 U3 snoRNA binding(GO:0034511)
1.7 8.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
1.7 6.7 GO:0004803 transposase activity(GO:0004803)
1.6 8.0 GO:0004925 prolactin receptor activity(GO:0004925)
1.6 4.7 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
1.5 6.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
1.4 4.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.4 18.5 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
1.4 11.2 GO:0004111 creatine kinase activity(GO:0004111)
1.4 5.5 GO:0070735 protein-glycine ligase activity(GO:0070735)
1.4 5.5 GO:0032810 sterol response element binding(GO:0032810)
1.4 8.1 GO:0003998 acylphosphatase activity(GO:0003998)
1.4 6.8 GO:0015204 urea transmembrane transporter activity(GO:0015204)
1.3 8.0 GO:0048039 ubiquinone binding(GO:0048039)
1.3 20.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.3 4.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.3 6.6 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
1.3 5.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.2 5.0 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
1.2 3.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.1 6.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.1 3.3 GO:0045322 unmethylated CpG binding(GO:0045322)
1.1 19.7 GO:0005522 profilin binding(GO:0005522)
1.1 16.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
1.1 5.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.1 19.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
1.0 14.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.0 13.2 GO:0001222 transcription corepressor binding(GO:0001222)
1.0 8.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.0 7.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.9 3.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.9 5.5 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.9 10.0 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.9 9.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.8 23.2 GO:0071949 FAD binding(GO:0071949)
0.8 14.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.8 5.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.8 6.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.8 9.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.8 2.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.7 7.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.7 3.0 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.7 4.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.7 4.4 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.7 2.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.7 2.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.7 2.7 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.7 13.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.7 2.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.6 3.8 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.6 6.9 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.6 2.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.6 3.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 8.8 GO:0008527 taste receptor activity(GO:0008527)
0.6 9.2 GO:0045499 chemorepellent activity(GO:0045499)
0.6 35.0 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.6 5.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.6 2.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.6 4.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.6 4.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.6 2.9 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.6 4.0 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.6 1.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.6 1.7 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.6 4.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.6 1.7 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.6 1.7 GO:0004103 choline kinase activity(GO:0004103)
0.5 9.3 GO:0070513 death domain binding(GO:0070513)
0.5 17.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.5 3.8 GO:0017002 activin-activated receptor activity(GO:0017002)
0.5 2.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.5 2.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.5 1.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.5 1.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.5 13.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.5 10.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.5 1.4 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.5 11.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.5 10.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.4 1.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.4 2.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 1.7 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.4 1.7 GO:0031716 calcitonin receptor binding(GO:0031716)
0.4 4.1 GO:0009374 biotin binding(GO:0009374)
0.4 4.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 2.0 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.4 4.8 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.4 4.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.4 5.5 GO:0070411 I-SMAD binding(GO:0070411)
0.4 7.0 GO:0019864 IgG binding(GO:0019864)
0.4 3.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.4 4.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.4 7.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 4.1 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.4 3.3 GO:0048495 Roundabout binding(GO:0048495)
0.4 6.9 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.4 5.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.4 34.8 GO:0019905 syntaxin binding(GO:0019905)
0.3 2.4 GO:0005523 tropomyosin binding(GO:0005523)
0.3 1.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 9.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 8.5 GO:0045503 dynein light chain binding(GO:0045503)
0.3 3.0 GO:0004969 histamine receptor activity(GO:0004969)
0.3 1.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.3 2.0 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.3 2.0 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.3 1.3 GO:0004461 lactose synthase activity(GO:0004461)
0.3 3.3 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.3 5.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.3 4.9 GO:0003680 AT DNA binding(GO:0003680)
0.3 13.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.3 12.2 GO:0008009 chemokine activity(GO:0008009)
0.3 8.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 3.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 3.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 2.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 2.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 2.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 3.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 4.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 3.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 1.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.3 4.6 GO:0035497 cAMP response element binding(GO:0035497)
0.3 5.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 2.1 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 0.8 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.3 14.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.3 2.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 2.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 2.2 GO:0004985 opioid receptor activity(GO:0004985)
0.2 1.2 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.2 6.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 7.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 12.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 4.6 GO:0050811 GABA receptor binding(GO:0050811)
0.2 1.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 2.1 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 1.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 2.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 9.3 GO:0030507 spectrin binding(GO:0030507)
0.2 3.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 3.9 GO:0051787 misfolded protein binding(GO:0051787)
0.2 1.2 GO:0043426 MRF binding(GO:0043426)
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 5.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 19.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 2.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.8 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 1.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 5.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 1.9 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.2 2.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.9 GO:0051425 PTB domain binding(GO:0051425)
0.2 1.1 GO:0032052 bile acid binding(GO:0032052)
0.2 5.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 7.2 GO:0017046 peptide hormone binding(GO:0017046)
0.2 1.3 GO:0015232 heme transporter activity(GO:0015232)
0.2 8.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 2.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 8.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 2.8 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 2.6 GO:0016918 retinal binding(GO:0016918)
0.2 11.7 GO:0002039 p53 binding(GO:0002039)
0.2 1.2 GO:0050815 phosphoserine binding(GO:0050815)
0.2 2.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 4.5 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.2 0.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 0.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 17.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.5 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 3.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.4 GO:0031419 cobalamin binding(GO:0031419)
0.2 0.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 5.5 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 5.0 GO:0005158 insulin receptor binding(GO:0005158)
0.2 3.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.2 3.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 4.3 GO:0042056 chemoattractant activity(GO:0042056)
0.1 24.3 GO:0008083 growth factor activity(GO:0008083)
0.1 15.8 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 1.6 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 1.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 10.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 181.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 19.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.4 GO:0010181 FMN binding(GO:0010181)
0.1 3.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.1 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.0 GO:1990405 protein antigen binding(GO:1990405)
0.1 3.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.6 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 1.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.6 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 1.9 GO:0043274 phospholipase binding(GO:0043274)
0.1 1.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.9 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.8 GO:0004601 peroxidase activity(GO:0004601)
0.1 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.4 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.9 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 1.9 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 2.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.0 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 2.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.0 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 2.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.1 GO:0030552 cAMP binding(GO:0030552)
0.1 37.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 4.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.2 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.1 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 3.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 9.3 GO:0008201 heparin binding(GO:0008201)
0.1 6.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 8.8 GO:0005319 lipid transporter activity(GO:0005319)
0.1 4.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.3 GO:0005537 mannose binding(GO:0005537)
0.1 0.4 GO:0050543 icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.4 GO:0005521 lamin binding(GO:0005521)
0.1 3.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 2.4 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 2.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 4.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0008198 ferrous iron binding(GO:0008198)
0.0 1.0 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 2.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 15.0 GO:0046873 metal ion transmembrane transporter activity(GO:0046873)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 9.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 6.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.8 28.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.6 3.8 PID ALK1 PATHWAY ALK1 signaling events
0.6 21.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.6 42.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.6 33.1 PID ATM PATHWAY ATM pathway
0.5 13.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.5 14.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.4 4.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.3 5.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.3 17.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.3 14.4 NABA COLLAGENS Genes encoding collagen proteins
0.3 8.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 13.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 7.0 PID BARD1 PATHWAY BARD1 signaling events
0.3 14.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.3 24.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.3 10.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 26.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.3 5.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 5.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 8.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 23.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 22.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 3.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 6.4 ST GA12 PATHWAY G alpha 12 Pathway
0.2 9.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 12.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 13.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 2.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 10.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 9.4 PID AP1 PATHWAY AP-1 transcription factor network
0.2 6.3 PID RAS PATHWAY Regulation of Ras family activation
0.2 1.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 5.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 9.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 7.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.5 PID P53 REGULATION PATHWAY p53 pathway
0.1 4.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 2.6 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 4.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.7 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 25.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.4 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.2 PID SHP2 PATHWAY SHP2 signaling
0.1 1.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 1.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.5 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 7.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 4.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.8 9.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.8 1.6 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.8 24.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.6 3.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.6 19.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.6 16.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.6 4.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.4 15.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.4 25.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.4 7.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.4 6.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.4 24.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 9.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.4 135.7 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.4 6.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.3 2.4 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.3 11.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 4.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 6.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 4.8 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.3 17.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 5.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 4.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 8.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.3 4.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 1.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 17.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 8.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.3 13.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.3 2.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.3 2.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 6.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 7.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 6.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 7.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 4.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 2.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 10.6 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 3.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 5.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 7.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 2.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 2.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 3.1 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.2 7.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 4.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 2.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 3.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 3.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 5.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 6.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 5.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 2.9 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 5.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 3.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 4.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.8 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.1 1.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 5.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 5.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 11.7 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 5.9 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 1.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 2.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 7.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 2.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 3.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 3.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 4.8 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.1 6.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.1 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 2.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 3.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation