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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EMX1

Z-value: 1.34

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Transcription factors associated with EMX1

Gene Symbol Gene ID Gene Info
EMX1
ENSG00000135638.9 empty spiracles homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX1hg19_v2_chr2_+_73144604_731446540.492.9e-14Click!

Activity profile of EMX1 motif

Sorted Z-values of EMX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_111794446 53.74 ENST00000527950.1
CRYAB
crystallin, alpha B
chr11_-_117748138 41.30 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr12_-_91546926 41.13 ENST00000550758.1
DCN
decorin
chr11_-_117747607 34.22 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_117747434 33.93 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chrX_+_13671225 33.37 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
chr12_-_6233828 25.41 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chrX_-_13835147 24.44 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr6_+_153552455 19.69 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr4_+_175204818 16.51 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr4_+_106631966 16.27 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr4_-_89205879 15.55 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr10_-_28571015 15.39 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr6_+_111580508 15.00 ENST00000368847.4
KIAA1919
KIAA1919
chr12_+_53773944 14.50 ENST00000551969.1
ENST00000327443.4
SP1
Sp1 transcription factor
chr16_+_58283814 14.22 ENST00000443128.2
ENST00000219299.4
CCDC113
coiled-coil domain containing 113
chr11_+_92085262 13.65 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr19_-_7968427 13.54 ENST00000539278.1
AC010336.1
Uncharacterized protein
chr11_-_129062093 13.24 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr3_+_111718036 12.67 ENST00000455401.2
TAGLN3
transgelin 3
chr6_+_151042224 12.61 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr3_+_111717600 12.33 ENST00000273368.4
TAGLN3
transgelin 3
chr6_+_151646800 11.68 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr3_+_111717511 11.52 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr1_+_202317815 11.28 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr4_+_169418195 10.91 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr10_-_71169031 10.47 ENST00000373307.1
TACR2
tachykinin receptor 2
chr4_-_10686475 10.32 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chrX_-_73512411 10.23 ENST00000602576.1
ENST00000429124.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr5_+_36608422 10.16 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_+_88896819 10.14 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr10_-_93392811 10.02 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr3_+_111718173 9.79 ENST00000494932.1
TAGLN3
transgelin 3
chr2_+_196313239 9.73 ENST00000413290.1
AC064834.1
AC064834.1
chr3_-_123339343 9.17 ENST00000578202.1
MYLK
myosin light chain kinase
chr14_+_93389425 9.12 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr12_-_48164812 8.70 ENST00000549151.1
ENST00000548919.1
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr5_+_66300446 8.56 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_+_160160283 8.52 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr6_-_46293378 8.52 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr3_+_130745688 8.45 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11
NIMA-related kinase 11
chr2_-_217560248 7.94 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr5_-_95297534 7.88 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr1_+_160160346 7.83 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr7_+_130126012 7.79 ENST00000341441.5
MEST
mesoderm specific transcript
chr11_-_13517565 7.72 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr3_+_115342349 7.71 ENST00000393780.3
GAP43
growth associated protein 43
chr12_-_118796910 7.71 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr7_+_130126165 7.64 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr10_-_5046042 7.56 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr5_-_24645078 7.41 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr15_+_62853562 7.38 ENST00000561311.1
TLN2
talin 2
chr3_-_38071122 7.31 ENST00000334661.4
PLCD1
phospholipase C, delta 1
chr4_-_8873531 7.26 ENST00000400677.3
HMX1
H6 family homeobox 1
chr12_-_114841703 7.26 ENST00000526441.1
TBX5
T-box 5
chr12_+_81110684 7.23 ENST00000228644.3
MYF5
myogenic factor 5
chr2_-_152830441 7.22 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr4_-_153601136 7.12 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chrX_+_54947229 7.10 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr11_-_128894053 7.09 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr8_+_50824233 7.09 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr1_+_62439037 7.00 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr6_-_49681235 6.98 ENST00000339139.4
CRISP2
cysteine-rich secretory protein 2
chr3_+_35722487 6.90 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_+_226013047 6.89 ENST00000366837.4
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr4_-_76944621 6.88 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr12_+_26348246 6.82 ENST00000422622.2
SSPN
sarcospan
chr3_+_158991025 6.72 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr8_-_17533838 6.57 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr10_+_7745303 6.55 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr2_+_171034646 6.52 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr4_-_186696425 6.45 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr8_+_98900132 6.43 ENST00000520016.1
MATN2
matrilin 2
chr9_+_131062367 6.40 ENST00000601297.1
AL359091.2
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr8_+_105235572 6.38 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr17_-_74163159 6.35 ENST00000591615.1
RNF157
ring finger protein 157
chrX_-_73512177 6.33 ENST00000603672.1
ENST00000418855.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr17_-_1532106 6.22 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr14_-_70883708 6.21 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr14_-_23652849 6.20 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr3_-_44519131 6.16 ENST00000425708.2
ENST00000396077.2
ZNF445
zinc finger protein 445
chr7_-_73038822 6.14 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL
MLX interacting protein-like
chr12_+_7013897 6.06 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr17_-_18430160 6.03 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A
chr10_+_5005598 5.98 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr16_-_29910853 5.96 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr12_+_7014064 5.89 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr2_-_214016314 5.88 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr4_-_74486347 5.77 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_-_48937821 5.76 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr5_+_125758813 5.76 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr19_+_15852203 5.76 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr9_-_95166884 5.67 ENST00000375561.5
OGN
osteoglycin
chr1_-_48937838 5.66 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr5_+_174151536 5.54 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr9_-_5304432 5.54 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr18_+_56530136 5.54 ENST00000591083.1
ZNF532
zinc finger protein 532
chr10_-_50970322 5.49 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr14_+_100485712 5.48 ENST00000544450.2
EVL
Enah/Vasp-like
chr2_+_113763031 5.48 ENST00000259211.6
IL36A
interleukin 36, alpha
chr19_-_39368887 5.36 ENST00000340740.3
ENST00000591812.1
RINL
Ras and Rab interactor-like
chr4_-_74486217 5.32 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr2_-_228582709 5.26 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr2_+_113816685 5.20 ENST00000393200.2
IL36RN
interleukin 36 receptor antagonist
chr8_+_105352050 5.19 ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr5_+_125758865 5.19 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chrX_-_14047996 5.18 ENST00000380523.4
ENST00000398355.3
GEMIN8
gem (nuclear organelle) associated protein 8
chr5_-_95297678 5.18 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr9_-_95166841 5.16 ENST00000262551.4
OGN
osteoglycin
chr4_+_41614909 5.06 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr1_-_242162375 5.02 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr18_-_61329118 5.02 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr12_-_112123524 4.99 ENST00000327551.6
BRAP
BRCA1 associated protein
chr12_+_7014126 4.99 ENST00000415834.1
ENST00000436789.1
LRRC23
leucine rich repeat containing 23
chr7_-_73038867 4.97 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL
MLX interacting protein-like
chr12_+_18414446 4.95 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr3_+_158787041 4.91 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr4_+_86396265 4.90 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr1_+_151735431 4.88 ENST00000321531.5
ENST00000315067.8
OAZ3
ornithine decarboxylase antizyme 3
chr7_+_142829162 4.87 ENST00000291009.3
PIP
prolactin-induced protein
chr7_-_83278322 4.72 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr19_-_58951496 4.65 ENST00000254166.3
ZNF132
zinc finger protein 132
chr7_+_43152191 4.57 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr20_+_3052264 4.55 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chr6_+_72926145 4.50 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr7_-_107642348 4.49 ENST00000393561.1
LAMB1
laminin, beta 1
chr10_+_7745232 4.48 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr6_+_39760129 4.44 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr12_-_11548496 4.38 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr3_-_99594948 4.34 ENST00000471562.1
ENST00000495625.2
FILIP1L
filamin A interacting protein 1-like
chr18_-_21891460 4.33 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr4_-_87281196 4.33 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr20_-_23860373 4.30 ENST00000304710.4
CST5
cystatin D
chr1_+_70876926 4.26 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr17_+_72426891 4.25 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr10_+_32856764 4.22 ENST00000375030.2
ENST00000375028.3
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr1_+_17559776 4.22 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chr8_+_99956662 4.22 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr3_-_130745571 4.21 ENST00000514044.1
ENST00000264992.3
ASTE1
asteroid homolog 1 (Drosophila)
chr6_+_72922590 4.19 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr13_+_73632897 4.18 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr18_-_53177984 4.16 ENST00000543082.1
TCF4
transcription factor 4
chr17_-_39743139 4.16 ENST00000167586.6
KRT14
keratin 14
chr16_-_53737722 4.13 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr2_+_202047843 4.09 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr3_+_152552685 4.09 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr12_+_106751436 4.08 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr6_+_72922505 4.07 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr11_-_5255861 4.06 ENST00000380299.3
HBD
hemoglobin, delta
chr3_-_160823158 4.05 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr13_-_28545276 4.04 ENST00000381020.7
CDX2
caudal type homeobox 2
chr11_+_24518723 4.04 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
LUZP2
leucine zipper protein 2
chr3_-_99595037 4.02 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr11_-_108093329 4.00 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr5_-_176889381 3.97 ENST00000393563.4
ENST00000512501.1
DBN1
drebrin 1
chr22_+_30752606 3.95 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
CCDC157
coiled-coil domain containing 157
chr10_-_50970382 3.90 ENST00000419399.1
ENST00000432695.1
OGDHL
oxoglutarate dehydrogenase-like
chr1_+_225600404 3.89 ENST00000366845.2
AC092811.1
AC092811.1
chr15_-_58571445 3.89 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr4_-_89205705 3.87 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr7_-_100860851 3.85 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr6_-_91296602 3.84 ENST00000369325.3
ENST00000369327.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr7_-_105029812 3.84 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr2_+_166095898 3.81 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr5_+_31193847 3.78 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr11_+_65554493 3.76 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr2_-_179672142 3.73 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr17_-_73663245 3.73 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr1_-_95391315 3.72 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr4_+_88754113 3.70 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr20_+_45947246 3.68 ENST00000599904.1
AL031666.2
HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
chr10_+_18629628 3.63 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr9_-_5339873 3.63 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr6_+_29429217 3.62 ENST00000396792.2
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr6_+_28317685 3.62 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
ZKSCAN3
zinc finger with KRAB and SCAN domains 3
chr13_-_38172863 3.60 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr2_-_166930131 3.59 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr16_-_66764119 3.59 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr14_+_32798547 3.58 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr11_+_119076745 3.55 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr3_-_160823040 3.53 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr19_-_3600549 3.50 ENST00000589966.1
TBXA2R
thromboxane A2 receptor
chr6_-_22297730 3.48 ENST00000306482.1
PRL
prolactin
chr1_-_233431458 3.48 ENST00000258229.9
ENST00000430153.1
PCNXL2
pecanex-like 2 (Drosophila)
chr4_-_87281224 3.47 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr7_-_143599207 3.47 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
FAM115A
family with sequence similarity 115, member A
chr14_+_68286516 3.45 ENST00000471583.1
ENST00000487270.1
ENST00000488612.1
RAD51B
RAD51 paralog B
chr5_-_160279207 3.42 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr11_-_102709441 3.39 ENST00000434103.1
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr9_-_21202204 3.37 ENST00000239347.3
IFNA7
interferon, alpha 7
chr7_-_27169801 3.35 ENST00000511914.1
HOXA4
homeobox A4
chr8_+_121137333 3.33 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
COL14A1
collagen, type XIV, alpha 1
chr16_-_53737795 3.30 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr21_-_42219065 3.29 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chrX_-_51797351 3.27 ENST00000375644.3
RP11-114H20.1
RP11-114H20.1
chr14_+_74034310 3.23 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr6_-_100912785 3.19 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr6_-_91296737 3.18 ENST00000369332.3
ENST00000369329.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr11_+_46958248 3.16 ENST00000536126.1
ENST00000278460.7
ENST00000378618.2
ENST00000395460.2
ENST00000378615.3
ENST00000543718.1
C11orf49
chromosome 11 open reading frame 49
chr2_-_208031943 3.15 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.5 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
3.4 41.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
3.4 10.1 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
3.0 9.1 GO:1901899 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
3.0 53.7 GO:0007021 tubulin complex assembly(GO:0007021)
2.6 7.9 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
2.6 7.7 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
2.5 2.5 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
2.4 24.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.4 7.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
2.4 14.5 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
2.2 15.4 GO:0071896 protein localization to adherens junction(GO:0071896)
2.2 8.7 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
2.0 10.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.9 13.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.8 5.5 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
1.8 7.0 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
1.8 5.3 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.7 8.6 GO:0060406 positive regulation of penile erection(GO:0060406)
1.6 16.4 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
1.6 11.1 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
1.5 5.9 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
1.5 1.5 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
1.4 7.2 GO:0038001 paracrine signaling(GO:0038001)
1.4 105.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
1.4 6.9 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
1.4 2.7 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
1.4 19.1 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.3 5.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.3 3.9 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
1.3 5.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
1.3 3.9 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.2 3.7 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
1.2 3.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
1.2 3.6 GO:1990523 bone regeneration(GO:1990523)
1.2 3.5 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
1.1 9.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.1 4.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.1 6.6 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.1 4.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
1.0 24.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.0 5.2 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
1.0 3.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.0 4.0 GO:0014807 regulation of somitogenesis(GO:0014807)
1.0 4.9 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
1.0 7.8 GO:0007258 JUN phosphorylation(GO:0007258)
1.0 2.9 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.0 2.9 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
1.0 2.9 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.9 5.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.8 19.5 GO:0003334 keratinocyte development(GO:0003334)
0.8 4.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.8 11.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.8 7.7 GO:0016198 axon choice point recognition(GO:0016198)
0.8 3.8 GO:0035063 nuclear speck organization(GO:0035063)
0.8 3.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.7 7.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.7 3.5 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.7 4.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.7 6.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.7 2.0 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.7 4.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.7 2.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.7 8.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.6 0.6 GO:0070668 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.6 5.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.6 7.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.6 2.8 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.6 1.7 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.5 17.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.5 2.7 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.5 1.9 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.5 4.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.5 7.4 GO:0021670 lateral ventricle development(GO:0021670)
0.5 5.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.5 3.6 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.4 0.4 GO:0061551 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) facioacoustic ganglion development(GO:1903375)
0.4 1.3 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.4 3.9 GO:0035799 ureter maturation(GO:0035799)
0.4 2.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.4 3.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4 2.0 GO:1904383 response to sodium phosphate(GO:1904383)
0.4 7.0 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.4 2.3 GO:1903960 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.4 3.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.4 2.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 1.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4 7.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.3 9.3 GO:0044458 motile cilium assembly(GO:0044458)
0.3 7.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 2.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.3 12.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.3 2.2 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.3 2.2 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.3 0.6 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.3 10.8 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.3 3.4 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.3 2.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.3 0.9 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 1.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 2.1 GO:0019532 oxalate transport(GO:0019532)
0.3 3.8 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.3 2.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.3 2.0 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3 1.4 GO:2001023 regulation of response to drug(GO:2001023)
0.3 1.4 GO:0061107 seminal vesicle development(GO:0061107)
0.3 3.3 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.3 4.1 GO:0015671 oxygen transport(GO:0015671)
0.3 6.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 2.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.3 7.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.3 0.5 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.2 1.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 0.2 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 0.7 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 4.0 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 2.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 11.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 0.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2 2.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.2 10.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 1.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 3.0 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.2 4.9 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.2 1.0 GO:0050955 thermoception(GO:0050955)
0.2 32.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 3.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.2 7.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 3.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 1.9 GO:0009642 response to light intensity(GO:0009642)
0.2 4.9 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.2 3.7 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 2.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 3.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 4.7 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.2 4.3 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 2.9 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.2 0.8 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.2 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 1.1 GO:1901374 epinephrine transport(GO:0048241) acetate ester transport(GO:1901374)
0.2 10.0 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 1.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 1.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.4 GO:0051697 protein delipidation(GO:0051697)
0.1 3.6 GO:0051642 centrosome localization(GO:0051642)
0.1 2.0 GO:0003091 renal water homeostasis(GO:0003091)
0.1 0.7 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.4 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.1 2.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 6.4 GO:0008347 glial cell migration(GO:0008347)
0.1 3.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.5 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 4.3 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 1.6 GO:0060009 Sertoli cell development(GO:0060009)
0.1 2.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 3.3 GO:0030199 collagen fibril organization(GO:0030199)
0.1 2.9 GO:0031529 ruffle organization(GO:0031529)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 12.5 GO:0007498 mesoderm development(GO:0007498)
0.1 1.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 11.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 11.3 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 1.4 GO:0006706 steroid catabolic process(GO:0006706)
0.1 3.7 GO:0035418 protein localization to synapse(GO:0035418)
0.1 4.4 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 5.0 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.1 0.6 GO:0000910 cytokinesis(GO:0000910)
0.1 0.7 GO:0043010 camera-type eye development(GO:0043010)
0.1 2.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 2.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 2.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 2.2 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.1 1.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 1.2 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 2.9 GO:0008360 regulation of cell shape(GO:0008360)
0.1 2.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 11.9 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 3.2 GO:0001657 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 1.1 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.8 GO:0036315 cellular response to sterol(GO:0036315)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.8 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 7.8 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 1.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:1901098 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.0 1.9 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 1.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.3 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.9 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 5.0 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 4.6 GO:0009408 response to heat(GO:0009408)
0.0 0.3 GO:0001765 membrane raft assembly(GO:0001765)
0.0 2.0 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 2.9 GO:0007601 visual perception(GO:0007601)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 2.4 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847) regulation of filopodium assembly(GO:0051489)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.5 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.5 GO:0014823 response to activity(GO:0014823)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 1.0 GO:0070268 cornification(GO:0070268)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.4 GO:0097224 sperm connecting piece(GO:0097224)
3.4 53.7 GO:0097512 cardiac myofibril(GO:0097512)
2.9 41.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
2.5 7.4 GO:0005879 axonemal microtubule(GO:0005879)
2.0 16.4 GO:0014802 terminal cisterna(GO:0014802)
1.5 4.5 GO:0005607 laminin-2 complex(GO:0005607)
1.3 9.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.3 15.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
1.1 7.7 GO:0032584 growth cone membrane(GO:0032584)
0.9 7.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.9 5.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.9 5.2 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.8 7.1 GO:0016013 syntrophin complex(GO:0016013)
0.8 3.9 GO:0044530 supraspliceosomal complex(GO:0044530)
0.6 3.6 GO:0002177 manchette(GO:0002177)
0.6 4.7 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.5 14.2 GO:0034451 centriolar satellite(GO:0034451)
0.5 2.7 GO:0071546 pi-body(GO:0071546)
0.5 7.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 6.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.5 8.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 1.4 GO:0097182 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.5 22.0 GO:0048786 presynaptic active zone(GO:0048786)
0.5 7.7 GO:0042583 chromaffin granule(GO:0042583)
0.4 3.3 GO:0005593 FACIT collagen trimer(GO:0005593)
0.4 3.5 GO:0016600 flotillin complex(GO:0016600)
0.4 9.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 2.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 5.7 GO:0097342 ripoptosome(GO:0097342)
0.3 2.2 GO:1990635 proximal dendrite(GO:1990635)
0.3 2.6 GO:0060077 inhibitory synapse(GO:0060077)
0.3 4.1 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 1.9 GO:0070938 contractile ring(GO:0070938)
0.3 3.5 GO:0031904 endosome lumen(GO:0031904)
0.3 14.0 GO:0002102 podosome(GO:0002102)
0.2 1.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 13.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 1.6 GO:0097452 GAIT complex(GO:0097452)
0.2 2.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 6.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 4.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 22.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 10.7 GO:0031672 A band(GO:0031672)
0.2 14.0 GO:0005902 microvillus(GO:0005902)
0.2 7.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 46.4 GO:0043209 myelin sheath(GO:0043209)
0.2 5.2 GO:0005921 gap junction(GO:0005921)
0.2 2.3 GO:0005869 dynactin complex(GO:0005869)
0.2 12.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 2.1 GO:0097225 sperm midpiece(GO:0097225)
0.2 17.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 3.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 2.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 14.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 2.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 20.3 GO:0001650 fibrillar center(GO:0001650)
0.1 3.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 2.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 4.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.2 GO:0005911 cell-cell junction(GO:0005911)
0.1 1.4 GO:0097440 apical dendrite(GO:0097440)
0.1 2.0 GO:0030673 axolemma(GO:0030673)
0.1 1.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 2.1 GO:0045178 basal part of cell(GO:0045178)
0.1 22.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 5.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 24.3 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 5.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 6.5 GO:0030018 Z disc(GO:0030018)
0.1 3.1 GO:0001533 cornified envelope(GO:0001533)
0.1 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 4.1 GO:0005604 basement membrane(GO:0005604)
0.1 2.4 GO:0016235 aggresome(GO:0016235)
0.1 8.9 GO:0001726 ruffle(GO:0001726)
0.1 6.8 GO:0030496 midbody(GO:0030496)
0.1 92.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 5.4 GO:0030027 lamellipodium(GO:0030027)
0.0 5.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.8 GO:0005884 actin filament(GO:0005884)
0.0 7.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 6.9 GO:0005938 cell cortex(GO:0005938)
0.0 2.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 4.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.0 GO:0031252 cell leading edge(GO:0031252)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 9.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
2.3 13.5 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
2.1 10.5 GO:0004995 tachykinin receptor activity(GO:0004995)
2.0 111.1 GO:0017080 sodium channel regulator activity(GO:0017080)
1.9 58.9 GO:0005212 structural constituent of eye lens(GO:0005212)
1.9 9.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.8 9.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.8 5.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
1.5 10.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.4 4.2 GO:1990254 keratin filament binding(GO:1990254)
1.3 7.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.3 7.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.3 3.9 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
1.2 3.5 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.2 5.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.2 3.5 GO:0005148 prolactin receptor binding(GO:0005148)
1.2 13.9 GO:0032027 myosin light chain binding(GO:0032027)
1.1 5.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
1.1 17.0 GO:0008179 adenylate cyclase binding(GO:0008179)
1.0 5.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
1.0 4.1 GO:0031685 adenosine receptor binding(GO:0031685)
1.0 3.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
1.0 32.1 GO:0019865 immunoglobulin binding(GO:0019865)
1.0 6.9 GO:0004301 epoxide hydrolase activity(GO:0004301)
1.0 4.9 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
1.0 2.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.8 4.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.8 6.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.8 2.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.7 3.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.7 7.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.7 4.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.7 12.4 GO:0005522 profilin binding(GO:0005522)
0.7 6.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.7 8.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.6 1.9 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.6 3.7 GO:0009378 four-way junction helicase activity(GO:0009378)
0.6 43.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.6 13.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.6 7.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 2.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.5 6.2 GO:0019534 toxin transporter activity(GO:0019534)
0.5 1.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.5 1.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.5 4.5 GO:0004969 histamine receptor activity(GO:0004969)
0.5 2.8 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.5 5.2 GO:0000150 recombinase activity(GO:0000150)
0.5 8.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.5 8.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.4 2.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.4 5.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.4 7.7 GO:0048018 receptor agonist activity(GO:0048018)
0.4 7.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 14.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.4 1.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.4 3.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.4 3.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 5.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 2.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 1.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3 1.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.3 4.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 29.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 4.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 5.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.3 1.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 2.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 3.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 2.2 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 1.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.3 6.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 56.1 GO:0051015 actin filament binding(GO:0051015)
0.2 2.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 3.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 0.7 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 0.5 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 2.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.2 8.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 2.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 6.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 6.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 0.8 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.2 20.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.2 0.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 1.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 3.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 1.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 4.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 2.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 3.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.9 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 23.4 GO:0035591 signaling adaptor activity(GO:0035591)
0.2 3.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 13.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 4.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.3 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.4 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 1.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 11.2 GO:0005179 hormone activity(GO:0005179)
0.1 5.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.1 9.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.2 GO:0070402 NADPH binding(GO:0070402)
0.1 1.3 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.7 GO:0004064 arylesterase activity(GO:0004064)
0.1 27.4 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 5.2 GO:0097110 scaffold protein binding(GO:0097110)
0.1 2.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 3.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 6.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 2.3 GO:0070840 dynein complex binding(GO:0070840)
0.1 3.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 10.3 GO:0008083 growth factor activity(GO:0008083)
0.1 18.4 GO:0003779 actin binding(GO:0003779)
0.1 1.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 5.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.9 GO:0070330 aromatase activity(GO:0070330)
0.1 35.9 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 1.4 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0 6.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.1 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0042166 acetylcholine binding(GO:0042166)
0.0 5.9 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 2.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 3.1 GO:0060090 binding, bridging(GO:0060090)
0.0 2.5 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 2.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 1.3 GO:0004518 nuclease activity(GO:0004518)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 2.7 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 55.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 2.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 3.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 7.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 8.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 12.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.3 12.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.3 8.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 10.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 2.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 14.5 PID AURORA B PATHWAY Aurora B signaling
0.2 50.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 10.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 7.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 4.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 2.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 3.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 1.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 9.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 9.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 4.9 ST GA13 PATHWAY G alpha 13 Pathway
0.1 5.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 24.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 7.4 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 3.6 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.7 PID CONE PATHWAY Visual signal transduction: Cones
0.1 24.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.7 PID BMP PATHWAY BMP receptor signaling
0.1 1.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 3.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 3.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 41.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.5 25.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.7 12.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.7 7.0 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.5 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.5 7.8 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.5 15.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 13.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.4 5.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.4 9.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 23.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.3 3.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 3.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 3.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 4.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 4.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 10.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 13.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 2.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 8.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 4.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 7.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 9.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 10.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 5.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 4.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.2 4.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 23.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 2.0 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2 4.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 5.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 7.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 2.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 3.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 4.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 3.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 4.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 8.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 5.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 21.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 14.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 2.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.4 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.1 7.8 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 2.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 3.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 9.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 5.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 6.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.6 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 2.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type