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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EMX2

Z-value: 0.79

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Transcription factors associated with EMX2

Gene Symbol Gene ID Gene Info
EMX2
ENSG00000170370.10 empty spiracles homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EMX2hg19_v2_chr10_+_119301928_119301955-0.101.5e-01Click!

Activity profile of EMX2 motif

Sorted Z-values of EMX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_11375179 4.78 ENST00000312511.3
PRM1
protamine 1
chr17_+_42422637 4.24 ENST00000053867.3
ENST00000588143.1
GRN
granulin
chr17_+_42422662 4.20 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN
granulin
chr4_-_89205879 4.05 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr11_+_92085262 4.00 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr12_-_123187890 3.79 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr11_-_59950486 3.75 ENST00000426738.2
ENST00000533023.1
ENST00000420732.2
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr12_-_123201337 3.74 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr16_-_28634874 3.55 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_-_59950519 3.49 ENST00000528851.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr11_-_59950622 3.45 ENST00000323961.3
ENST00000412309.2
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr12_-_10282836 3.44 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr5_-_140013275 3.43 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr18_+_21693306 3.43 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr9_+_111624577 3.33 ENST00000333999.3
ACTL7A
actin-like 7A
chr3_-_141747950 3.32 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_149754227 3.11 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr16_-_21663919 2.89 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr1_+_111773349 2.84 ENST00000533831.2
CHI3L2
chitinase 3-like 2
chr3_-_151047327 2.74 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr4_-_120243545 2.46 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr4_-_100356551 2.42 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_-_104905840 2.42 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr9_+_125132803 2.41 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr16_-_21663950 2.36 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr11_-_104972158 2.32 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr3_-_141719195 2.31 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_120935894 2.30 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr9_+_125133315 2.26 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_-_34503867 2.24 ENST00000589443.1
ENST00000454519.3
ENST00000586369.1
TBC1D3B
TBC1 domain family, member 3B
chr12_+_101988774 2.20 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr20_+_30697298 2.16 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr2_-_85625857 2.08 ENST00000453973.1
CAPG
capping protein (actin filament), gelsolin-like
chr3_+_121774202 1.99 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr17_-_15244894 1.96 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
TEKT3
tektin 3
chr19_+_50016610 1.93 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr8_-_38008783 1.91 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr12_-_10282742 1.90 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr11_+_7110165 1.85 ENST00000306904.5
RBMXL2
RNA binding motif protein, X-linked-like 2
chr12_+_29302119 1.84 ENST00000536681.3
FAR2
fatty acyl CoA reductase 2
chr22_+_45725524 1.82 ENST00000405548.3
FAM118A
family with sequence similarity 118, member A
chr8_-_133687778 1.75 ENST00000518642.1
LRRC6
leucine rich repeat containing 6
chr6_+_6588316 1.70 ENST00000379953.2
LY86
lymphocyte antigen 86
chr17_-_39093672 1.70 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr17_-_34757039 1.67 ENST00000455054.2
ENST00000308078.7
TBC1D3H
TBC1D3C
TBC1 domain family, member 3H
TBC1 domain family, member 3C
chr4_-_170897045 1.64 ENST00000508313.1
RP11-205M3.3
RP11-205M3.3
chr12_-_58220078 1.64 ENST00000549039.1
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr16_+_15489603 1.62 ENST00000568766.1
ENST00000287594.7
RP11-1021N1.1
MPV17L
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr10_-_47239738 1.57 ENST00000413193.2
AGAP10
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr4_+_80584903 1.57 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr2_+_48796120 1.56 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr12_+_101988627 1.54 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr1_-_182921119 1.51 ENST00000423786.1
SHCBP1L
SHC SH2-domain binding protein 1-like
chr12_-_24102576 1.49 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
SOX5
SRY (sex determining region Y)-box 5
chr2_-_99279928 1.49 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr6_+_72926145 1.49 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_206858232 1.45 ENST00000294981.4
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr8_-_133687813 1.45 ENST00000250173.1
ENST00000519595.1
LRRC6
leucine rich repeat containing 6
chr12_-_22063787 1.45 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_+_117544366 1.44 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr9_-_128246769 1.41 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr5_+_81575281 1.40 ENST00000380167.4
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr11_-_63376013 1.39 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr12_-_10978957 1.38 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr5_-_137475071 1.34 ENST00000265191.2
NME5
NME/NM23 family member 5
chr3_+_40518599 1.31 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619
zinc finger protein 619
chr1_+_174844645 1.31 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr5_-_111093081 1.30 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr3_-_122512619 1.27 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr8_+_31497271 1.24 ENST00000520407.1
NRG1
neuregulin 1
chr1_-_92952433 1.24 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr1_-_67142710 1.23 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr14_+_54863667 1.20 ENST00000335183.6
CDKN3
cyclin-dependent kinase inhibitor 3
chr6_-_134639180 1.18 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr4_-_168155169 1.18 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr17_+_62461569 1.17 ENST00000603557.1
ENST00000605096.1
MILR1
mast cell immunoglobulin-like receptor 1
chr11_-_36310958 1.17 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9
COMM domain containing 9
chr9_-_115095123 1.15 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr4_-_100356291 1.13 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr18_+_61637159 1.13 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
SERPINB8
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr1_+_36549676 1.04 ENST00000207457.3
TEKT2
tektin 2 (testicular)
chr5_+_54455946 1.04 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr9_-_21202204 1.04 ENST00000239347.3
IFNA7
interferon, alpha 7
chr18_-_5419797 1.03 ENST00000542146.1
ENST00000427684.2
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr17_+_66521936 1.03 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr12_+_60083118 1.02 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr11_+_74303575 1.01 ENST00000263681.2
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr12_+_26164645 1.00 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr5_-_75919217 1.00 ENST00000504899.1
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr5_-_9630463 1.00 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr16_-_28374829 0.99 ENST00000532254.1
NPIPB6
nuclear pore complex interacting protein family, member B6
chr18_+_6729725 0.99 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr12_-_118796910 0.99 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr11_+_122753391 0.98 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr6_+_44187242 0.98 ENST00000393844.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr17_+_7239821 0.98 ENST00000158762.3
ENST00000570457.2
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr7_+_138145076 0.97 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr3_+_11314099 0.95 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
ATG7
autophagy related 7
chr4_-_123377880 0.95 ENST00000226730.4
IL2
interleukin 2
chr16_+_11038345 0.95 ENST00000409790.1
CLEC16A
C-type lectin domain family 16, member A
chr11_+_122709200 0.93 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr12_-_86650077 0.92 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr18_+_20513278 0.91 ENST00000327155.5
RBBP8
retinoblastoma binding protein 8
chr16_-_29479154 0.91 ENST00000549950.1
RP11-345J4.3
Uncharacterized protein
chr15_+_84115868 0.90 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr2_+_122494676 0.90 ENST00000455432.1
TSN
translin
chrX_-_72347916 0.90 ENST00000373518.1
NAP1L6
nucleosome assembly protein 1-like 6
chr10_-_115904361 0.89 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr3_-_48956818 0.89 ENST00000408959.2
ARIH2OS
ariadne homolog 2 opposite strand
chr4_-_185275104 0.89 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr3_+_52245458 0.89 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr1_+_192778161 0.89 ENST00000235382.5
RGS2
regulator of G-protein signaling 2, 24kDa
chr2_+_234826016 0.89 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr1_-_146082633 0.88 ENST00000605317.1
ENST00000604938.1
ENST00000339388.5
NBPF11
neuroblastoma breakpoint family, member 11
chr14_-_90420862 0.88 ENST00000556005.1
ENST00000555872.1
EFCAB11
EF-hand calcium binding domain 11
chr6_+_29079668 0.86 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr2_+_196313239 0.86 ENST00000413290.1
AC064834.1
AC064834.1
chr12_+_112279782 0.85 ENST00000550735.2
MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
chr8_-_57123815 0.85 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr6_+_63921399 0.84 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr6_-_46048116 0.84 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr16_+_31885079 0.83 ENST00000300870.10
ENST00000394846.3
ZNF267
zinc finger protein 267
chr7_-_104909435 0.82 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr21_-_43735628 0.82 ENST00000291525.10
ENST00000518498.1
TFF3
trefoil factor 3 (intestinal)
chr1_-_39347255 0.81 ENST00000454994.2
ENST00000357771.3
GJA9
gap junction protein, alpha 9, 59kDa
chr11_+_117198545 0.81 ENST00000533153.1
ENST00000278935.3
ENST00000525416.1
CEP164
centrosomal protein 164kDa
chr11_+_10476851 0.80 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr5_-_75919253 0.80 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr6_+_44187334 0.80 ENST00000313248.7
ENST00000427851.2
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr12_-_53171128 0.78 ENST00000332411.2
KRT76
keratin 76
chr2_-_62733476 0.78 ENST00000335390.5
TMEM17
transmembrane protein 17
chr6_+_34725263 0.78 ENST00000374018.1
ENST00000374017.3
SNRPC
small nuclear ribonucleoprotein polypeptide C
chr5_-_111754948 0.78 ENST00000261486.5
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr12_+_21525818 0.76 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr16_+_18995249 0.76 ENST00000569532.1
ENST00000304381.5
TMC7
transmembrane channel-like 7
chr19_-_51920952 0.75 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr9_-_21368075 0.74 ENST00000449498.1
IFNA13
interferon, alpha 13
chr7_+_117251671 0.74 ENST00000468795.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr12_-_53715328 0.74 ENST00000547757.1
ENST00000394384.3
ENST00000209873.4
AAAS
achalasia, adrenocortical insufficiency, alacrimia
chr4_-_113437328 0.72 ENST00000313341.3
NEUROG2
neurogenin 2
chr5_-_55412774 0.72 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr20_+_36405665 0.72 ENST00000373469.1
CTNNBL1
catenin, beta like 1
chr12_-_86650045 0.71 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr18_-_19994830 0.71 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr5_+_129083772 0.69 ENST00000564719.1
KIAA1024L
KIAA1024-like
chr12_+_58176525 0.69 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr12_-_68696652 0.68 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr19_+_54466179 0.68 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr5_-_111093167 0.68 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr4_+_96012614 0.68 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr4_-_103746924 0.68 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr8_+_12803176 0.68 ENST00000524591.2
KIAA1456
KIAA1456
chr11_-_13517565 0.66 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr14_-_69261310 0.66 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr1_-_19615744 0.65 ENST00000361640.4
AKR7A3
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr5_+_140514782 0.65 ENST00000231134.5
PCDHB5
protocadherin beta 5
chrX_+_144908928 0.62 ENST00000408967.2
TMEM257
transmembrane protein 257
chr8_+_119294456 0.61 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr19_+_15852203 0.61 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr4_+_88571429 0.61 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr1_+_225600404 0.61 ENST00000366845.2
AC092811.1
AC092811.1
chr2_-_207023918 0.61 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr7_+_107224364 0.61 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr12_-_112279694 0.61 ENST00000443596.1
ENST00000442119.1
MAPKAPK5-AS1
MAPKAPK5 antisense RNA 1
chr3_+_38080691 0.60 ENST00000308059.6
ENST00000346219.3
ENST00000452631.2
DLEC1
deleted in lung and esophageal cancer 1
chr2_+_157330081 0.60 ENST00000409674.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr5_-_111092930 0.59 ENST00000257435.7
NREP
neuronal regeneration related protein
chr5_-_111312622 0.58 ENST00000395634.3
NREP
neuronal regeneration related protein
chr5_-_58571935 0.57 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_+_113616317 0.57 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C
chr8_+_70404996 0.56 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr1_+_146714291 0.56 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
CHD1L
chromodomain helicase DNA binding protein 1-like
chr15_+_64680003 0.55 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr5_-_76788317 0.55 ENST00000296679.4
WDR41
WD repeat domain 41
chr4_+_74702214 0.55 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr2_-_207082748 0.55 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr4_-_89205705 0.55 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr21_-_42219065 0.54 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr6_+_150690028 0.53 ENST00000229447.5
ENST00000344419.3
IYD
iodotyrosine deiodinase
chr5_-_58882219 0.53 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_113568207 0.53 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chrX_+_78003204 0.53 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr16_-_30102547 0.53 ENST00000279386.2
TBX6
T-box 6
chr6_-_76782371 0.52 ENST00000369950.3
ENST00000369963.3
IMPG1
interphotoreceptor matrix proteoglycan 1
chr6_+_28092338 0.52 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr7_-_16505440 0.52 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr9_-_21217310 0.52 ENST00000380216.1
IFNA16
interferon, alpha 16
chr6_+_72922505 0.51 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr21_-_43735446 0.51 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr18_+_29769978 0.49 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr12_-_11091862 0.49 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chr6_+_26204825 0.49 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr19_+_12848299 0.47 ENST00000357332.3
ASNA1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr1_+_146373546 0.47 ENST00000446760.2
NBPF12
neuroblastoma breakpoint family, member 12
chr7_+_115862858 0.47 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr5_-_132200477 0.46 ENST00000296875.2
GDF9
growth differentiation factor 9
chr15_+_59903975 0.46 ENST00000560585.1
ENST00000396065.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr6_+_34725181 0.46 ENST00000244520.5
SNRPC
small nuclear ribonucleoprotein polypeptide C
chrX_+_135730373 0.45 ENST00000370628.2
CD40LG
CD40 ligand
chr1_+_160709076 0.45 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7

Network of associatons between targets according to the STRING database.

First level regulatory network of EMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.2 4.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.9 3.4 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.7 2.0 GO:0032641 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.6 1.9 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.6 1.8 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.5 2.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 3.0 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.4 1.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.4 1.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.4 1.8 GO:0015862 uridine transport(GO:0015862)
0.3 1.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 3.2 GO:0036159 inner dynein arm assembly(GO:0036159) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.3 1.0 GO:1901859 late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) single-organism membrane invagination(GO:1902534)
0.3 3.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 1.9 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.3 3.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 5.3 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.3 4.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 1.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 1.0 GO:0032053 ciliary basal body organization(GO:0032053)
0.2 0.7 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.9 GO:2000317 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.2 1.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 0.7 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 0.7 GO:0048382 mesendoderm development(GO:0048382)
0.2 1.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.2 1.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2 1.5 GO:0044351 macropinocytosis(GO:0044351)
0.2 1.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 0.9 GO:0050955 thermoception(GO:0050955)
0.2 1.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 0.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 2.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 0.8 GO:0035063 nuclear speck organization(GO:0035063)
0.2 3.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.2 1.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 0.9 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.2 5.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.2 0.5 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.9 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.1 1.0 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 1.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 2.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 5.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.8 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.5 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.9 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 4.8 GO:0030261 chromosome condensation(GO:0030261)
0.1 1.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 2.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.6 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.9 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 2.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 2.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.8 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.5 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.3 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.1 0.8 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.8 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.8 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.2 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 1.8 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.2 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1 1.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.3 GO:0071231 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) cellular response to folic acid(GO:0071231)
0.1 0.6 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.6 GO:0070166 enamel mineralization(GO:0070166)
0.1 5.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 1.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.4 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.4 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.1 0.9 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.8 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.4 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.5 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 4.7 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.5 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 1.0 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 4.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.4 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 4.7 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.6 GO:0006295 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0034505 tooth mineralization(GO:0034505)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) cellular response to temperature stimulus(GO:0071502)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) axon midline choice point recognition(GO:0016199) response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 2.1 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 9.2 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.7 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.1 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.9 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.7 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.0 1.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.3 GO:0021591 ventricular system development(GO:0021591)
0.0 0.7 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.4 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.0 0.8 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.5 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.3 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.9 GO:0098869 cellular oxidant detoxification(GO:0098869)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.7 GO:0097179 protease inhibitor complex(GO:0097179)
0.7 3.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.5 1.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 1.9 GO:0030061 mitochondrial crista(GO:0030061)
0.3 1.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 3.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 1.0 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 1.5 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.7 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 3.9 GO:0032982 myosin filament(GO:0032982)
0.1 2.1 GO:0008290 F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.1 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.1 0.8 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.2 GO:0000243 commitment complex(GO:0000243)
0.1 0.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 2.0 GO:0002080 acrosomal membrane(GO:0002080)
0.1 5.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 1.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 8.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 2.3 GO:0030673 axolemma(GO:0030673)
0.1 0.8 GO:0043025 neuronal cell body(GO:0043025)
0.1 0.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.8 GO:0036038 MKS complex(GO:0036038)
0.1 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 2.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 4.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.7 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.2 GO:0042629 mast cell granule(GO:0042629)
0.0 5.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 1.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.9 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.3 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.1 3.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.9 3.6 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.6 1.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 4.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.5 3.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.4 3.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 1.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.3 4.7 GO:0050700 CARD domain binding(GO:0050700)
0.3 1.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 1.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 1.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 0.9 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.3 0.9 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 3.1 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.3 1.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3 3.7 GO:0031432 titin binding(GO:0031432)
0.3 2.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.3 3.1 GO:0019864 IgG binding(GO:0019864)
0.2 0.7 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 1.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 5.3 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 2.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 1.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.5 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.6 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 1.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 2.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.4 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.1 0.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.0 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 1.7 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.2 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.4 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.7 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.4 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 5.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.1 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 2.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.8 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 7.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 2.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 2.0 GO:0015026 coreceptor activity(GO:0015026)
0.0 8.6 GO:0005125 cytokine activity(GO:0005125)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.1 GO:0030552 cAMP binding(GO:0030552)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 6.9 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 2.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 6.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 4.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 2.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 3.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.8 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 3.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 4.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 3.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 3.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 3.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 3.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 3.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 4.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 2.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 4.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 6.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.7 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins