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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ESR1

Z-value: 1.67

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Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ENSG00000091831.17 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESR1hg19_v2_chr6_+_152128810_1521288270.321.5e-06Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_106209368 29.55 ENST00000390548.2
ENST00000390549.2
ENST00000390542.2
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106054659 29.47 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_+_23248512 26.26 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr22_+_23165153 23.62 ENST00000390317.2
immunoglobulin lambda variable 2-8
chr22_+_23247030 22.32 ENST00000390324.2
immunoglobulin lambda joining 3
chr19_-_45826125 20.93 ENST00000221476.3
creatine kinase, muscle
chr22_+_23046750 19.92 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr2_-_89513402 19.55 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr22_+_23243156 18.76 ENST00000390323.2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr22_+_23241661 17.35 ENST00000390322.2
immunoglobulin lambda joining 2
chr2_-_89310012 16.54 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr14_-_106642049 16.16 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr11_+_1891380 15.76 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
lymphocyte-specific protein 1
chr19_+_49838653 15.10 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr2_-_89292422 13.95 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr22_+_23077065 13.62 ENST00000390310.2
immunoglobulin lambda variable 2-18
chr22_+_22930626 13.25 ENST00000390302.2
immunoglobulin lambda variable 2-33 (non-functional)
chr22_+_22681656 12.34 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr22_+_22936998 12.04 ENST00000390303.2
immunoglobulin lambda variable 3-32 (non-functional)
chr19_+_42381173 11.66 ENST00000221972.3
CD79a molecule, immunoglobulin-associated alpha
chr3_-_46506358 11.47 ENST00000417439.1
ENST00000431944.1
lactotransferrin
chr22_+_23029188 11.31 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr15_+_89181974 10.88 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr11_+_47270436 10.81 ENST00000395397.3
ENST00000405576.1
nuclear receptor subfamily 1, group H, member 3
chr15_+_89182178 10.78 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr12_+_112204691 10.30 ENST00000416293.3
ENST00000261733.2
aldehyde dehydrogenase 2 family (mitochondrial)
chr11_+_47270475 10.28 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
nuclear receptor subfamily 1, group H, member 3
chr22_+_22676808 10.04 ENST00000390290.2
immunoglobulin lambda variable 1-51
chr1_+_118148556 9.97 ENST00000369448.3
family with sequence similarity 46, member C
chr9_+_139874683 9.70 ENST00000444903.1
prostaglandin D2 synthase 21kDa (brain)
chr22_+_23089870 9.61 ENST00000390311.2
immunoglobulin lambda variable 3-16
chr20_+_48429233 9.46 ENST00000417961.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr20_+_48429356 9.07 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr15_-_20170354 8.83 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr16_+_1291240 8.74 ENST00000561736.1
tryptase alpha/beta 1
chr14_-_107078851 8.11 ENST00000390628.2
immunoglobulin heavy variable 1-58
chr19_+_58790314 8.09 ENST00000196548.5
ENST00000608843.1
Zinc finger protein 8
zinc finger protein 8
chr14_-_106453155 8.04 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr15_+_89182156 7.80 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr14_-_106725723 7.65 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr17_-_34207295 7.64 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr22_-_23922410 7.59 ENST00000249053.3
immunoglobulin lambda-like polypeptide 1
chr19_-_13213662 7.48 ENST00000264824.4
lymphoblastic leukemia derived sequence 1
chrX_-_107019181 7.44 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22 domain family, member 3
chr22_+_23154239 7.33 ENST00000390315.2
immunoglobulin lambda variable 3-10
chr10_+_114135952 7.32 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
acyl-CoA synthetase long-chain family member 5
chr3_+_47021168 7.06 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
neurobeachin-like 2
chr13_-_46964177 6.75 ENST00000389908.3
KIAA0226-like
chr1_+_209848749 6.64 ENST00000367029.4
G0/G1switch 2
chr3_-_52488048 6.63 ENST00000232975.3
troponin C type 1 (slow)
chr7_+_149535455 6.48 ENST00000223210.4
ENST00000460379.1
zinc finger protein 862
chr19_-_10445399 6.31 ENST00000592945.1
intercellular adhesion molecule 3
chr22_+_22735135 6.28 ENST00000390297.2
immunoglobulin lambda variable 1-44
chr2_-_220110111 6.27 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
galactosidase, beta 1-like
chr12_-_13256593 6.23 ENST00000542415.1
ENST00000324458.8
germ cell associated 1
chr20_+_3801162 6.20 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
adaptor-related protein complex 5, sigma 1 subunit
chr3_-_15469006 6.19 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
methyltransferase like 6
chr22_-_51016433 6.19 ENST00000405237.3
carnitine palmitoyltransferase 1B (muscle)
chr19_+_36024310 6.17 ENST00000222286.4
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr10_+_88728189 6.12 ENST00000416348.1
adipogenesis regulatory factor
chr1_+_27561104 6.07 ENST00000361771.3
WD and tetratricopeptide repeats 1
chr2_+_30454390 5.91 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
limb bud and heart development
chr4_+_190992087 5.88 ENST00000553598.1
double homeobox 4 like 7
chr22_-_51021397 5.87 ENST00000406938.2
choline kinase beta
chr2_-_89247338 5.72 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr12_-_14721283 5.71 ENST00000240617.5
phospholipase B domain containing 1
chr22_-_24096630 5.59 ENST00000248948.3
pre-B lymphocyte 3
chr19_-_42746714 5.58 ENST00000222330.3
glycogen synthase kinase 3 alpha
chr22_-_24096562 5.57 ENST00000398465.3
pre-B lymphocyte 3
chr11_-_47270341 5.53 ENST00000529444.1
ENST00000530453.1
ENST00000537863.1
ENST00000529788.1
ENST00000444355.2
ENST00000527256.1
ENST00000529663.1
ENST00000256997.3
acid phosphatase 2, lysosomal
chr12_-_13256571 5.47 ENST00000545401.1
ENST00000432710.2
ENST00000351606.6
germ cell associated 1
chr11_-_64527425 5.46 ENST00000377432.3
phosphorylase, glycogen, muscle
chr3_+_15468862 5.39 ENST00000396842.2
ELL associated factor 1
chr9_+_123970052 5.37 ENST00000373823.3
gelsolin
chr19_+_35759824 5.37 ENST00000343550.5
upstream transcription factor 2, c-fos interacting
chr16_-_28621312 5.35 ENST00000314752.7
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_-_111970353 5.31 ENST00000369732.3
oviductal glycoprotein 1, 120kDa
chr19_+_7968728 5.30 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
mitogen-activated protein kinase kinase 7
chr21_+_40817749 5.29 ENST00000380637.3
ENST00000380634.1
ENST00000458295.1
ENST00000440288.2
ENST00000380631.1
SH3 domain binding glutamic acid-rich protein
chr19_-_42498231 5.25 ENST00000602133.1
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chrX_-_106959631 5.24 ENST00000486554.1
ENST00000372390.4
TSC22 domain family, member 3
chr5_-_1112141 5.23 ENST00000264930.5
solute carrier family 12 (potassium/chloride transporter), member 7
chr22_+_39745930 5.17 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
synaptogyrin 1
chr19_+_56652686 5.16 ENST00000592949.1
zinc finger protein 444
chr17_-_36348610 5.09 ENST00000339023.4
ENST00000354664.4
TBC1 domain family, member 3
chr19_-_42498369 4.96 ENST00000302102.5
ENST00000545399.1
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr5_-_131347501 4.94 ENST00000543479.1
acyl-CoA synthetase long-chain family member 6
chr14_+_106384295 4.86 ENST00000449410.1
ENST00000429431.1
KIAA0125
chr16_+_85061367 4.81 ENST00000538274.1
ENST00000258180.3
KIAA0513
chr11_+_43380459 4.79 ENST00000299240.6
ENST00000039989.4
tetratricopeptide repeat domain 17
chr17_-_34503867 4.74 ENST00000589443.1
ENST00000454519.3
ENST00000586369.1
TBC1 domain family, member 3B
chr17_-_34757039 4.73 ENST00000455054.2
ENST00000308078.7
TBC1 domain family, member 3H
TBC1 domain family, member 3C
chr17_-_34808047 4.72 ENST00000592614.1
ENST00000591542.1
ENST00000330458.7
ENST00000341264.6
ENST00000592987.1
ENST00000400684.4
TBC1 domain family, member 3G
TBC1 domain family, member 3H
chr22_+_39853258 4.71 ENST00000341184.6
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr17_+_36283971 4.69 ENST00000327454.6
ENST00000378174.5
TBC1 domain family, member 3F
chrY_+_9365489 4.68 ENST00000428845.2
ENST00000444056.1
ENST00000429039.1
testis specific protein, Y-linked 10
chr7_+_30068260 4.67 ENST00000440706.2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr22_-_23922448 4.66 ENST00000438703.1
ENST00000330377.2
immunoglobulin lambda-like polypeptide 1
chrY_+_9175073 4.63 ENST00000426950.2
ENST00000383008.1
testis specific protein, Y-linked 4
chr5_-_42825983 4.63 ENST00000506577.1
selenoprotein P, plasma, 1
chr8_+_103563792 4.63 ENST00000285402.3
outer dense fiber of sperm tails 1
chr17_-_27507395 4.59 ENST00000354329.4
ENST00000527372.1
myosin XVIIIA
chr17_-_27507377 4.59 ENST00000531253.1
myosin XVIIIA
chrY_+_9324922 4.55 ENST00000440215.2
ENST00000446779.2
testis specific protein, Y-linked 6, pseudogene
chr4_+_668348 4.50 ENST00000511290.1
myosin, light chain 5, regulatory
chr19_+_8478154 4.49 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr11_-_1036706 4.48 ENST00000421673.2
mucin 6, oligomeric mucus/gel-forming
chr12_+_52301175 4.46 ENST00000388922.4
activin A receptor type II-like 1
chr2_+_231090433 4.39 ENST00000486687.2
ENST00000350136.5
ENST00000392045.3
ENST00000417495.3
ENST00000343805.6
ENST00000420434.3
SP140 nuclear body protein
chr19_+_2389784 4.36 ENST00000332578.3
transmembrane protease, serine 9
chr19_-_51512804 4.35 ENST00000594211.1
ENST00000376832.4
kallikrein-related peptidase 9
chr11_-_59383617 4.35 ENST00000263847.1
oxysterol binding protein
chr2_+_233925064 4.33 ENST00000359570.5
ENST00000538935.1
inositol polyphosphate-5-phosphatase, 145kDa
chr17_-_34592032 4.31 ENST00000457979.3
TBC1 domain family, member 3C
chr6_-_136871957 4.28 ENST00000354570.3
microtubule-associated protein 7
chr1_+_9711781 4.24 ENST00000536656.1
ENST00000377346.4
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr9_-_35619539 4.24 ENST00000396757.1
CD72 molecule
chrY_+_9195406 4.17 ENST00000287721.9
ENST00000383005.2
ENST00000383000.1
ENST00000330628.9
ENST00000537415.1
testis specific protein, Y-linked 8
chr19_-_54784353 4.11 ENST00000391746.1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr16_-_55866997 4.06 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr6_-_2903514 4.00 ENST00000380698.4
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr6_-_49712147 3.96 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr9_-_33264557 3.91 ENST00000473781.1
ENST00000488499.1
BCL2-associated athanogene
chr14_+_75536280 3.90 ENST00000238686.8
zinc finger, C2HC-type containing 1C
chr20_+_61584026 3.88 ENST00000370351.4
ENST00000370349.3
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr2_+_11679963 3.87 ENST00000263834.5
growth regulation by estrogen in breast cancer 1
chr1_+_245133278 3.85 ENST00000366522.2
EF-hand calcium binding domain 2
chr2_-_160761179 3.77 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
lymphocyte antigen 75
LY75-CD302 readthrough
chr8_+_11141925 3.76 ENST00000221086.3
myotubularin related protein 9
chr6_-_41703296 3.75 ENST00000373033.1
transcription factor EB
chr7_-_99569468 3.75 ENST00000419575.1
alpha-2-glycoprotein 1, zinc-binding
chr14_+_94577074 3.75 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr16_+_29471210 3.74 ENST00000360423.7
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr5_+_134240588 3.72 ENST00000254908.6
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr17_-_79869340 3.72 ENST00000538936.2
phosphate cytidylyltransferase 2, ethanolamine
chr17_-_39677971 3.71 ENST00000393976.2
keratin 15
chr6_-_91006461 3.70 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr11_-_615570 3.70 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr16_+_1383602 3.68 ENST00000426824.3
ENST00000397488.2
ENST00000562208.1
ENST00000568887.1
BAI1-associated protein 3
chr8_+_11351876 3.62 ENST00000529894.1
B lymphoid tyrosine kinase
chr20_-_62258394 3.61 ENST00000370077.1
glucocorticoid modulatory element binding protein 2
chr5_-_693500 3.56 ENST00000360578.5
tubulin polymerization promoting protein
chr9_+_100174344 3.55 ENST00000422139.2
tudor domain containing 7
chr11_-_61684962 3.52 ENST00000394836.2
RAB3A interacting protein (rabin3)-like 1
chr12_-_124457371 3.46 ENST00000238156.3
ENST00000545037.1
coiled-coil domain containing 92
chr19_-_11639931 3.42 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT signalling integrator
chr16_+_19729586 3.42 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQ motif containing K
chr14_+_75536335 3.41 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
zinc finger, C2HC-type containing 1C
chr3_-_13461807 3.37 ENST00000254508.5
nucleoporin 210kDa
chr8_+_120885949 3.35 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chrX_+_77166172 3.34 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr1_+_76262552 3.32 ENST00000263187.3
mutS homolog 4
chr16_+_1290725 3.30 ENST00000461509.2
tryptase alpha/beta 1
chr1_-_236445251 3.28 ENST00000354619.5
ENST00000327333.8
ERO1-like beta (S. cerevisiae)
chr14_-_106471723 3.27 ENST00000390595.2
immunoglobulin heavy variable 1-3
chr10_+_131265443 3.27 ENST00000306010.7
O-6-methylguanine-DNA methyltransferase
chr5_-_131347583 3.27 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
acyl-CoA synthetase long-chain family member 6
chr16_+_30210552 3.22 ENST00000338971.5
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr8_+_11351494 3.21 ENST00000259089.4
B lymphoid tyrosine kinase
chr4_+_190992387 3.18 ENST00000554906.2
ENST00000553820.2
double homeobox 4 like 7
chr14_+_103995546 3.16 ENST00000299202.4
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr8_-_41522779 3.16 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ankyrin 1, erythrocytic
chr11_-_6677018 3.16 ENST00000299441.3
dachsous cadherin-related 1
chr6_+_35265586 3.15 ENST00000542066.1
ENST00000316637.5
differentially expressed in FDCP 6 homolog (mouse)
chr14_-_21492113 3.14 ENST00000554094.1
NDRG family member 2
chr5_+_110559784 3.14 ENST00000282356.4
calcium/calmodulin-dependent protein kinase IV
chr5_-_132202329 3.11 ENST00000378673.2
growth differentiation factor 9
chr16_+_66914264 3.11 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr11_+_14665373 3.10 ENST00000455098.2
phosphodiesterase 3B, cGMP-inhibited
chr9_-_139096955 3.10 ENST00000371748.5
LIM homeobox 3
chr3_+_93781728 3.06 ENST00000314622.4
NOP2/Sun domain family, member 3
chr16_+_89686991 3.06 ENST00000393092.3
dipeptidase 1 (renal)
chr2_-_242041607 3.04 ENST00000434791.1
ENST00000401626.2
ENST00000439144.1
ENST00000406593.1
ENST00000495694.1
ENST00000407095.3
ENST00000391980.2
MTERF domain containing 2
chr1_-_59043166 3.04 ENST00000371225.2
tumor-associated calcium signal transducer 2
chr22_+_22550113 3.03 ENST00000390285.3
immunoglobulin lambda variable 6-57
chr12_-_124457257 3.03 ENST00000545891.1
coiled-coil domain containing 92
chr16_-_28621298 3.01 ENST00000566189.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr4_-_89080003 2.96 ENST00000237612.3
ATP-binding cassette, sub-family G (WHITE), member 2
chr16_-_21289627 2.96 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr22_-_19137796 2.95 ENST00000086933.2
goosecoid homeobox 2
chr15_+_42696992 2.94 ENST00000561817.1
calpain 3, (p94)
chr1_-_24151903 2.93 ENST00000436439.2
ENST00000374490.3
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr3_-_122512619 2.93 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr3_-_15106747 2.92 ENST00000449354.2
ENST00000444840.2
ENST00000253686.2
mitochondrial ribosomal protein S25
chr5_+_149109825 2.92 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr16_+_20420849 2.91 ENST00000575584.1
ENST00000331849.4
acyl-CoA synthetase medium-chain family member 5
chr4_-_860950 2.91 ENST00000511980.1
ENST00000510799.1
cyclin G associated kinase
chr12_+_57914742 2.90 ENST00000551351.1
methyl-CpG binding domain protein 6
chr19_-_11639910 2.89 ENST00000588998.1
ENST00000586149.1
ECSIT signalling integrator
chr3_+_121554046 2.88 ENST00000273668.2
ENST00000451944.2
ELL associated factor 2
chr14_-_21492251 2.85 ENST00000554398.1
NDRG family member 2
chr6_+_24495067 2.85 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr1_+_55107449 2.84 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
maestro heat-like repeat family member 7
chr17_-_19771216 2.82 ENST00000395544.4
unc-51 like autophagy activating kinase 2
chr15_+_42697018 2.81 ENST00000397204.4
calpain 3, (p94)
chr6_+_32121218 2.78 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
palmitoyl-protein thioesterase 2
chr6_-_159420780 2.77 ENST00000449822.1
radial spoke 3 homolog (Chlamydomonas)
chr11_+_17756279 2.77 ENST00000265969.6
potassium voltage-gated channel, Shaw-related subfamily, member 1
chr5_-_154230130 2.75 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
fatty acid hydroxylase domain containing 2
chr14_+_103995503 2.73 ENST00000389749.4
tRNA methyltransferase 61 homolog A (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
7.0 21.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
3.8 11.5 GO:2000308 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
3.1 9.2 GO:1903028 positive regulation of opsonization(GO:1903028)
2.9 29.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
2.0 15.8 GO:0007506 gonadal mesoderm development(GO:0007506)
1.9 7.6 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.9 20.9 GO:0006600 creatine metabolic process(GO:0006600)
1.9 5.6 GO:0006258 UDP-glucose catabolic process(GO:0006258)
1.8 5.3 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
1.7 6.6 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
1.6 12.7 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
1.6 4.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
1.4 4.3 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
1.3 5.4 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
1.3 4.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.3 10.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
1.2 85.8 GO:0006910 phagocytosis, recognition(GO:0006910)
1.2 11.9 GO:0001955 blood vessel maturation(GO:0001955)
1.2 5.9 GO:2000035 positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035)
1.2 18.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.1 3.4 GO:0097359 UDP-glucosylation(GO:0097359)
1.1 6.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
1.1 3.3 GO:0071284 cellular response to lead ion(GO:0071284)
1.1 5.4 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
1.1 3.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
1.0 3.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
1.0 10.3 GO:0006069 ethanol oxidation(GO:0006069)
1.0 6.1 GO:0072719 cellular response to cisplatin(GO:0072719)
1.0 3.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
1.0 3.1 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
1.0 2.9 GO:1905224 clathrin-coated pit assembly(GO:1905224)
1.0 3.8 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.9 2.7 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.9 7.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.9 3.6 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.9 2.6 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.9 1.7 GO:0002384 hepatic immune response(GO:0002384)
0.9 3.5 GO:0019046 release from viral latency(GO:0019046)
0.8 4.2 GO:0060374 positive regulation of neutrophil apoptotic process(GO:0033031) mast cell differentiation(GO:0060374)
0.8 2.5 GO:0019417 sulfur oxidation(GO:0019417)
0.8 2.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.8 1.6 GO:0042325 regulation of phosphorylation(GO:0042325)
0.8 3.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.8 4.7 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.8 138.9 GO:0002377 immunoglobulin production(GO:0002377)
0.8 6.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.8 2.3 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.8 18.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.8 3.0 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.7 3.7 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.7 2.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.7 4.9 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.7 2.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.7 2.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.7 1.4 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.7 64.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.7 2.0 GO:0032641 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.7 2.6 GO:0035995 detection of muscle stretch(GO:0035995)
0.6 5.5 GO:0006552 leucine catabolic process(GO:0006552)
0.6 1.8 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.6 3.0 GO:0007507 heart development(GO:0007507)
0.6 2.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.6 4.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.6 1.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.6 1.1 GO:0002331 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.6 2.8 GO:0021759 globus pallidus development(GO:0021759)
0.6 3.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.5 3.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.5 10.9 GO:0006067 ethanol metabolic process(GO:0006067) ethanol catabolic process(GO:0006068)
0.5 11.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.5 9.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 1.6 GO:1904300 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.5 2.7 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.5 2.1 GO:0001757 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.5 2.6 GO:1901093 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.5 1.5 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.5 3.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.5 1.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 1.5 GO:1903626 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.5 1.5 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.5 1.9 GO:0097676 regulation of mRNA export from nucleus(GO:0010793) cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.5 1.4 GO:0090155 glucosylceramide biosynthetic process(GO:0006679) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.5 3.3 GO:0071462 cellular response to water stimulus(GO:0071462)
0.5 0.9 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.5 1.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.5 7.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.5 1.4 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.4 2.2 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.4 1.3 GO:0035634 response to stilbenoid(GO:0035634)
0.4 1.7 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.4 5.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 2.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.4 3.7 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.4 0.8 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.4 1.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.4 4.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.4 6.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.4 4.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.4 1.9 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.4 2.3 GO:0030279 negative regulation of ossification(GO:0030279)
0.4 1.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.4 3.3 GO:0051026 chiasma assembly(GO:0051026)
0.4 3.3 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.4 2.9 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.4 3.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.4 1.8 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.3 2.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.3 2.1 GO:0010193 response to ozone(GO:0010193)
0.3 6.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3 1.7 GO:0046968 peptide antigen transport(GO:0046968)
0.3 27.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.3 3.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 2.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.3 1.3 GO:0021539 subthalamus development(GO:0021539)
0.3 3.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.3 8.0 GO:0030488 tRNA methylation(GO:0030488)
0.3 2.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 3.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.3 3.0 GO:0015886 heme transport(GO:0015886)
0.3 2.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 2.0 GO:0030916 otic vesicle formation(GO:0030916)
0.3 2.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 18.1 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.3 7.1 GO:0030220 platelet formation(GO:0030220)
0.3 1.7 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.3 3.0 GO:0006554 lysine catabolic process(GO:0006554)
0.3 6.4 GO:0007141 male meiosis I(GO:0007141)
0.3 0.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 0.8 GO:0048867 stem cell fate determination(GO:0048867)
0.3 2.1 GO:0060501 negative regulation of keratinocyte differentiation(GO:0045617) positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.3 1.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.3 0.8 GO:0043366 beta selection(GO:0043366)
0.3 1.3 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.3 6.2 GO:0051194 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.3 1.3 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.3 2.5 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.2 2.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.2 6.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 2.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 2.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2 1.9 GO:0015705 iodide transport(GO:0015705)
0.2 0.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 1.4 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 1.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 2.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 1.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 1.4 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.2 1.6 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 0.6 GO:0031622 positive regulation of fever generation(GO:0031622)
0.2 1.7 GO:0006477 protein sulfation(GO:0006477)
0.2 1.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.2 6.8 GO:0060384 innervation(GO:0060384)
0.2 5.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.2 13.4 GO:0006968 cellular defense response(GO:0006968)
0.2 2.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 3.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 2.0 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 2.3 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2 0.5 GO:0071233 cellular response to leucine(GO:0071233)
0.2 2.7 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 1.6 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.2 1.4 GO:0046618 drug export(GO:0046618)
0.2 0.7 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 0.5 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 1.2 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.2 5.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.2 2.3 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 2.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 1.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.8 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 42.8 GO:0002250 adaptive immune response(GO:0002250)
0.2 1.5 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.2 2.9 GO:0006853 carnitine shuttle(GO:0006853)
0.1 1.8 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 1.2 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.1 0.6 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 3.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 3.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.8 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 0.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.5 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 1.5 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.6 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 1.9 GO:0050900 leukocyte migration(GO:0050900)
0.1 2.0 GO:0030575 nuclear body organization(GO:0030575)
0.1 0.5 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.9 GO:0051014 actin filament severing(GO:0051014)
0.1 2.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.7 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.1 1.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 6.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 1.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 2.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 1.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.4 GO:0070942 cytolysis in other organism involved in symbiotic interaction(GO:0051801) neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944) neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 1.7 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 1.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 2.9 GO:0016579 protein deubiquitination(GO:0016579)
0.1 0.8 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 3.8 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 2.4 GO:0007616 long-term memory(GO:0007616)
0.1 1.7 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 2.8 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 1.8 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 0.7 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.6 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 2.4 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 0.3 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 1.5 GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling(GO:1905114)
0.1 0.8 GO:0097264 self proteolysis(GO:0097264)
0.1 0.9 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 5.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 1.9 GO:0016032 viral process(GO:0016032) multi-organism cellular process(GO:0044764)
0.1 0.9 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 1.7 GO:0006525 arginine metabolic process(GO:0006525)
0.1 1.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 1.0 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.3 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.1 3.7 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.1 1.0 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 1.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 2.9 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 6.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 0.6 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.1 0.9 GO:2000278 regulation of DNA biosynthetic process(GO:2000278)
0.1 2.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 3.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 1.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 4.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.8 GO:0051354 negative regulation of oxidoreductase activity(GO:0051354)
0.1 1.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 1.9 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 1.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 2.7 GO:0099531 neurotransmitter secretion(GO:0007269) presynaptic process involved in chemical synaptic transmission(GO:0099531) signal release from synapse(GO:0099643)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 1.8 GO:0006611 protein export from nucleus(GO:0006611)
0.0 5.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 2.5 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
0.0 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 1.5 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 4.8 GO:0044782 cilium organization(GO:0044782)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 7.0 GO:0006909 phagocytosis(GO:0006909)
0.0 2.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.5 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 3.0 GO:0007286 spermatid development(GO:0007286)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.7 GO:0050776 regulation of immune response(GO:0050776)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.3 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 1.0 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 3.1 GO:0070268 cornification(GO:0070268)
0.0 0.6 GO:0015695 organic cation transport(GO:0015695)
0.0 2.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 2.7 GO:0045087 innate immune response(GO:0045087)
0.0 2.8 GO:0006006 glucose metabolic process(GO:0006006)
0.0 1.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.6 GO:0030815 negative regulation of cAMP metabolic process(GO:0030815)
0.0 0.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.9 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.1 GO:0031960 response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.9 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.9 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 1.1 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.5 GO:0071746 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
2.1 2.1 GO:0005775 vacuolar lumen(GO:0005775)
2.0 5.9 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
1.8 85.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.7 11.7 GO:0019815 B cell receptor complex(GO:0019815)
1.6 11.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
1.3 6.4 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
1.1 6.6 GO:1990584 cardiac Troponin complex(GO:1990584)
1.1 3.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.9 10.2 GO:0044327 dendritic spine head(GO:0044327)
0.8 3.3 GO:0005713 recombination nodule(GO:0005713)
0.8 1.6 GO:0005927 muscle tendon junction(GO:0005927)
0.7 4.6 GO:0001520 outer dense fiber(GO:0001520)
0.7 1.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.6 1.7 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.6 6.1 GO:0033391 chromatoid body(GO:0033391)
0.5 1.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.5 1.0 GO:0071546 pi-body(GO:0071546)
0.5 4.7 GO:0097427 microtubule bundle(GO:0097427)
0.5 31.9 GO:0015030 Cajal body(GO:0015030)
0.5 5.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.4 1.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 1.5 GO:0032044 DSIF complex(GO:0032044)
0.4 2.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.4 5.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.4 9.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.4 5.4 GO:0030478 actin cap(GO:0030478)
0.4 1.8 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.4 2.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 56.8 GO:0072562 blood microparticle(GO:0072562)
0.3 2.5 GO:0014802 terminal cisterna(GO:0014802)
0.3 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.3 2.5 GO:0030897 HOPS complex(GO:0030897)
0.3 2.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 3.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 0.7 GO:0098536 deuterosome(GO:0098536)
0.2 2.1 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.7 GO:0044305 calyx of Held(GO:0044305)
0.2 2.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 2.3 GO:0045180 basal cortex(GO:0045180)
0.2 6.9 GO:0030673 axolemma(GO:0030673)
0.2 13.1 GO:0001772 immunological synapse(GO:0001772)
0.2 3.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 1.5 GO:0097165 nuclear stress granule(GO:0097165)
0.2 2.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 3.0 GO:0097440 apical dendrite(GO:0097440)
0.2 2.4 GO:0010369 chromocenter(GO:0010369)
0.2 2.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 3.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 2.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.2 14.9 GO:0016459 myosin complex(GO:0016459)
0.2 1.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 0.9 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 5.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 3.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 3.9 GO:0034451 centriolar satellite(GO:0034451)
0.1 3.2 GO:0042629 mast cell granule(GO:0042629)
0.1 8.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.7 GO:0031430 M band(GO:0031430)
0.1 1.7 GO:0017119 Golgi transport complex(GO:0017119)
0.1 2.3 GO:0000145 exocyst(GO:0000145)
0.1 1.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 4.3 GO:0005581 collagen trimer(GO:0005581)
0.1 167.2 GO:0005615 extracellular space(GO:0005615)
0.1 2.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 1.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 2.8 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 2.2 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.1 1.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 6.8 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 8.8 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 2.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 18.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.1 0.5 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 8.3 GO:0005814 centriole(GO:0005814)
0.1 1.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.8 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1 4.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 6.2 GO:0005882 intermediate filament(GO:0005882)
0.1 0.6 GO:0032039 integrator complex(GO:0032039)
0.1 1.0 GO:0035579 specific granule membrane(GO:0035579)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.9 GO:0031941 filamentous actin(GO:0031941)
0.1 1.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 5.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 6.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 8.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 2.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 6.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 1.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 1.9 GO:0098858 actin-based cell projection(GO:0098858)
0.0 1.7 GO:0000428 DNA-directed RNA polymerase complex(GO:0000428)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.7 GO:0001726 ruffle(GO:0001726)
0.0 10.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.6 GO:0043195 terminal bouton(GO:0043195)
0.0 4.8 GO:0045177 apical part of cell(GO:0045177)
0.0 0.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 5.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.5 GO:0008859 exoribonuclease II activity(GO:0008859)
5.3 21.1 GO:0032810 sterol response element binding(GO:0032810)
2.6 20.9 GO:0004111 creatine kinase activity(GO:0004111)
2.4 9.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
2.1 115.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
2.0 5.9 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
2.0 5.9 GO:0004103 choline kinase activity(GO:0004103)
1.9 18.5 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
1.8 5.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.5 6.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.4 4.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
1.4 10.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.4 12.7 GO:0043426 MRF binding(GO:0043426)
1.4 5.5 GO:0008184 glycogen phosphorylase activity(GO:0008184)
1.2 6.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.2 4.7 GO:0017089 glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
1.1 3.4 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
1.1 4.5 GO:0016361 activin receptor activity, type I(GO:0016361)
1.1 3.3 GO:0032767 copper-dependent protein binding(GO:0032767)
1.1 7.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.0 3.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
1.0 4.1 GO:0023029 MHC class Ib protein binding(GO:0023029)
1.0 17.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
1.0 179.4 GO:0003823 antigen binding(GO:0003823)
0.9 3.7 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.9 7.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.9 3.6 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.8 1.6 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.8 4.1 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.8 6.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.8 9.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.7 3.7 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.7 3.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.7 7.9 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.7 2.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.6 7.0 GO:0031013 troponin I binding(GO:0031013)
0.6 4.3 GO:0008142 oxysterol binding(GO:0008142)
0.6 1.8 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.6 3.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.6 4.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.6 7.2 GO:0045159 myosin II binding(GO:0045159)
0.6 1.8 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.6 1.7 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.6 4.5 GO:0034235 GPI anchor binding(GO:0034235)
0.5 3.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.5 2.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.5 3.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5 1.5 GO:0097677 STAT family protein binding(GO:0097677)
0.5 1.5 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.5 6.8 GO:0031432 titin binding(GO:0031432)
0.5 5.3 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.5 1.4 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.5 1.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.5 5.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 2.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.4 1.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.4 3.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 2.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.4 3.3 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.4 13.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.4 7.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.4 1.5 GO:0004104 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.4 2.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.4 1.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 1.9 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.4 1.5 GO:0043398 HLH domain binding(GO:0043398)
0.4 1.9 GO:0002046 opsin binding(GO:0002046)
0.4 3.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.4 3.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.4 3.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.4 2.9 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.4 1.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 3.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.4 1.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 2.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 2.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 1.4 GO:0035939 microsatellite binding(GO:0035939)
0.3 3.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 3.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 2.6 GO:0071253 connexin binding(GO:0071253)
0.3 2.9 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.3 6.8 GO:0050811 GABA receptor binding(GO:0050811)
0.3 1.6 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.3 5.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.3 0.6 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.3 1.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3 3.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 2.3 GO:0019863 IgE binding(GO:0019863)
0.3 3.5 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.3 5.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 0.8 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 1.4 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.3 0.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 3.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 1.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 3.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 2.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 1.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 6.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 2.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 1.0 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.2 6.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 1.2 GO:0050436 microfibril binding(GO:0050436)
0.2 2.7 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 2.4 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 1.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 3.7 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 0.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2 0.6 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 0.6 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.2 2.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 1.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.2 1.3 GO:0034711 inhibin binding(GO:0034711)
0.2 2.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 0.9 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 0.7 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 3.5 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 1.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 2.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 1.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 0.7 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 1.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 2.5 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.2 4.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 3.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.2 2.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.2 4.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 2.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2 1.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 1.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 1.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 32.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 3.9 GO:0005521 lamin binding(GO:0005521)
0.1 1.7 GO:0008494 translation activator activity(GO:0008494)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 6.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 1.6 GO:0089720 caspase binding(GO:0089720)
0.1 1.3 GO:0004707 MAP kinase activity(GO:0004707)
0.1 22.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.4 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 5.9 GO:0043531 ADP binding(GO:0043531)
0.1 7.0 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 9.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 7.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.5 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 5.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.0 GO:0032027 myosin light chain binding(GO:0032027)
0.1 3.9 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 2.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 3.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.6 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.3 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 3.0 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 2.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 2.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 2.9 GO:0030332 cyclin binding(GO:0030332)
0.1 0.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 1.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.7 GO:0022841 outward rectifier potassium channel activity(GO:0015271) potassium ion leak channel activity(GO:0022841)
0.1 1.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 3.2 GO:0042393 histone binding(GO:0042393)
0.1 3.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 4.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 2.0 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 4.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 1.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.6 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 3.3 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 1.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 2.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.6 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 5.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 2.2 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 1.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.4 9.8 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.4 19.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.4 9.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 34.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.3 14.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 4.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 6.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 20.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 3.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 5.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 3.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 7.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 1.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 5.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 1.7 ST STAT3 PATHWAY STAT3 Pathway
0.2 8.3 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 4.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 6.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 4.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 4.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 5.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.7 PID IL3 PATHWAY IL3-mediated signaling events
0.1 2.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 2.2 PID CD40 PATHWAY CD40/CD40L signaling
0.1 5.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 5.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 3.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 3.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 3.0 PID AURORA A PATHWAY Aurora A signaling
0.1 3.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 3.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 11.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 15.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.5 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.9 18.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.7 1.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.6 11.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.5 27.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.4 11.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 35.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 6.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.3 12.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 0.9 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.3 5.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 1.5 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.3 5.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.3 1.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 3.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 5.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 14.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 7.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 3.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 6.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 3.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 6.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 26.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 2.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 3.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 16.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 3.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 3.3 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.2 2.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 2.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 14.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 1.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 4.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2 1.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 4.7 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 4.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 4.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 6.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 7.4 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.1 4.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 2.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 7.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.1 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.1 2.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 4.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 4.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 8.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.8 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 5.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 4.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 3.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 8.1 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 1.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 5.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.0 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.8 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 3.0 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases