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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ETS1

Z-value: 2.71

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Transcription factors associated with ETS1

Gene Symbol Gene ID Gene Info
ENSG00000134954.10 ETS proto-oncogene 1, transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETS1hg19_v2_chr11_-_128392085_1283922320.359.0e-08Click!

Activity profile of ETS1 motif

Sorted Z-values of ETS1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_10450287 62.29 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr19_+_1077393 60.36 ENST00000590577.1
histocompatibility (minor) HA-1
chr21_-_46340770 59.26 ENST00000397854.3
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr13_-_46756351 56.05 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr7_-_5569588 55.66 ENST00000417101.1
actin, beta
chr20_+_43514320 49.17 ENST00000372839.3
ENST00000428262.1
ENST00000445830.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr19_-_10450328 49.04 ENST00000160262.5
intercellular adhesion molecule 3
chr12_-_110888103 47.57 ENST00000426440.1
ENST00000228825.7
actin related protein 2/3 complex, subunit 3, 21kDa
chr20_+_43514315 47.39 ENST00000353703.4
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr2_-_230786619 45.29 ENST00000389045.3
ENST00000409677.1
thyroid hormone receptor interactor 12
chr1_+_40505891 44.34 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr7_+_5085452 42.23 ENST00000353796.3
ENST00000396912.1
ENST00000396904.2
RB-associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr11_+_118230287 38.39 ENST00000252108.3
ENST00000431736.2
ubiquitination factor E4A
chr17_-_4852332 37.66 ENST00000572383.1
profilin 1
chr1_-_111743285 36.75 ENST00000357640.4
DENN/MADD domain containing 2D
chr10_-_121302195 36.71 ENST00000369103.2
regulator of G-protein signaling 10
chr9_-_88969303 36.67 ENST00000277141.6
ENST00000375963.3
zinc finger, CCHC domain containing 6
chr4_-_84035905 36.28 ENST00000311507.4
placenta-specific 8
chr1_+_16767195 36.15 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP endocytosis associated 2
chr19_-_39826639 36.05 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
glia maturation factor, gamma
chr1_+_16767167 35.32 ENST00000337132.5
NECAP endocytosis associated 2
chr20_-_2451395 35.30 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
small nuclear ribonucleoprotein polypeptides B and B1
chr1_+_40506392 34.84 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_-_31510181 34.26 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr9_-_88969339 34.24 ENST00000375960.2
ENST00000375961.2
zinc finger, CCHC domain containing 6
chr17_+_1944790 34.22 ENST00000575162.1
diphthamide biosynthesis 1
chr4_-_84035868 33.98 ENST00000426923.2
ENST00000509973.1
placenta-specific 8
chr21_-_46340884 33.16 ENST00000302347.5
ENST00000517819.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_-_58343319 32.94 ENST00000395074.2
leupaxin
chr1_-_167487758 32.41 ENST00000362089.5
CD247 molecule
chr3_-_121379739 32.40 ENST00000428394.2
ENST00000314583.3
hematopoietic cell-specific Lyn substrate 1
chr3_-_64009102 32.30 ENST00000478185.1
ENST00000482510.1
ENST00000497323.1
ENST00000492933.1
ENST00000295901.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr17_+_4618734 32.29 ENST00000571206.1
arrestin, beta 2
chr6_-_31509714 32.08 ENST00000456662.1
ENST00000431908.1
ENST00000456976.1
ENST00000428450.1
ENST00000453105.2
ENST00000418897.1
ENST00000415382.2
ENST00000449074.2
ENST00000419020.1
ENST00000428098.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr1_-_167487808 31.87 ENST00000392122.3
CD247 molecule
chr1_-_113247543 31.83 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr15_+_75074410 31.67 ENST00000439220.2
c-src tyrosine kinase
chr8_+_29953163 31.00 ENST00000518192.1
leptin receptor overlapping transcript-like 1
chr22_-_36924944 30.94 ENST00000405442.1
ENST00000402116.1
eukaryotic translation initiation factor 3, subunit D
chr12_-_120907374 30.94 ENST00000550458.1
serine/arginine-rich splicing factor 9
chr14_-_69864993 30.86 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr10_-_43892668 30.17 ENST00000544000.1
heterogeneous nuclear ribonucleoprotein F
chr22_-_36925186 30.09 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
eukaryotic translation initiation factor 3, subunit D
chr7_+_102988082 29.75 ENST00000292644.3
ENST00000544811.1
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr14_+_57735614 29.67 ENST00000261558.3
adaptor-related protein complex 5, mu 1 subunit
chr16_-_88717482 29.63 ENST00000261623.3
cytochrome b-245, alpha polypeptide
chr5_+_271752 29.62 ENST00000505221.1
ENST00000509581.1
ENST00000507528.1
programmed cell death 6
chr1_+_32716840 29.58 ENST00000336890.5
lymphocyte-specific protein tyrosine kinase
chr17_-_62502639 29.24 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr2_+_219081817 29.17 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
actin related protein 2/3 complex, subunit 2, 34kDa
chr16_-_30204987 28.90 ENST00000569282.1
ENST00000567436.1
bolA family member 2B
chr19_+_35645618 28.50 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD domain containing ion transport regulator 5
chr19_+_35645817 28.46 ENST00000423817.3
FXYD domain containing ion transport regulator 5
chr6_-_32160622 28.40 ENST00000487761.1
ENST00000375040.3
G-protein signaling modulator 3
chr1_+_32739733 28.08 ENST00000333070.4
lymphocyte-specific protein tyrosine kinase
chr17_-_4852243 27.90 ENST00000225655.5
profilin 1
chr5_+_134094461 27.69 ENST00000452510.2
ENST00000354283.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr5_+_65222384 27.26 ENST00000380943.2
ENST00000416865.2
ENST00000380939.2
ENST00000380936.1
ENST00000380935.1
erbb2 interacting protein
chr16_+_30205225 27.25 ENST00000345535.4
ENST00000251303.6
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
chr15_-_65810042 27.15 ENST00000321147.6
dipeptidyl-peptidase 8
chr15_+_75074385 27.11 ENST00000220003.9
c-src tyrosine kinase
chr2_+_85804614 26.99 ENST00000263864.5
ENST00000409760.1
vesicle-associated membrane protein 8
chr16_+_29465822 26.91 ENST00000330181.5
ENST00000351581.4
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr2_+_65454863 26.73 ENST00000260641.5
ARP2 actin-related protein 2 homolog (yeast)
chr1_+_198608146 26.67 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr16_-_88717423 26.55 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
cytochrome b-245, alpha polypeptide
chr15_-_65809991 26.42 ENST00000559526.1
ENST00000358939.4
ENST00000560665.1
ENST00000321118.7
ENST00000339244.5
ENST00000300141.6
dipeptidyl-peptidase 8
chr2_+_65454926 26.11 ENST00000542850.1
ENST00000377982.4
ARP2 actin-related protein 2 homolog (yeast)
chr1_-_25256368 25.86 ENST00000308873.6
runt-related transcription factor 3
chr12_+_7055631 25.85 ENST00000543115.1
ENST00000399448.1
protein tyrosine phosphatase, non-receptor type 6
chr16_-_66968055 25.78 ENST00000568572.1
family with sequence similarity 96, member B
chr1_+_32716857 25.77 ENST00000482949.1
ENST00000495610.2
lymphocyte-specific protein tyrosine kinase
chr12_-_92539614 25.58 ENST00000256015.3
B-cell translocation gene 1, anti-proliferative
chr16_+_30483962 25.39 ENST00000356798.6
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr8_+_29952914 25.15 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
leptin receptor overlapping transcript-like 1
chr16_-_29465668 25.00 ENST00000569622.1
BolA-like protein 2
chr13_-_31191642 24.67 ENST00000405805.1
high mobility group box 1
chr17_-_38721711 24.64 ENST00000578085.1
ENST00000246657.2
chemokine (C-C motif) receptor 7
chr3_-_64009658 24.59 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr19_+_49838653 24.49 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr8_+_22438009 24.46 ENST00000409417.1
PDZ and LIM domain 2 (mystique)
chr10_-_27149851 24.39 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
abl-interactor 1
chr17_+_43299241 24.39 ENST00000328118.3
formin-like 1
chr2_+_233415363 24.26 ENST00000409514.1
ENST00000409098.1
ENST00000409495.1
ENST00000409167.3
ENST00000409322.1
ENST00000409394.1
eukaryotic translation initiation factor 4E family member 2
chr2_+_69001913 24.24 ENST00000409030.3
ENST00000409220.1
Rho GTPase activating protein 25
chr7_+_141438393 24.23 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
single-stranded DNA binding protein 1, mitochondrial
chr17_-_76123101 24.10 ENST00000392467.3
transmembrane channel-like 6
chr12_+_7055767 24.09 ENST00000447931.2
protein tyrosine phosphatase, non-receptor type 6
chr5_+_65222299 24.03 ENST00000284037.5
erbb2 interacting protein
chr5_-_150284532 23.96 ENST00000394226.2
ENST00000446148.2
ENST00000274599.5
ENST00000418587.2
zinc finger protein 300
chr17_-_17184605 23.93 ENST00000268717.5
COP9 signalosome subunit 3
chr10_-_27149792 23.82 ENST00000376140.3
ENST00000376170.4
abl-interactor 1
chr16_-_66968265 23.69 ENST00000567511.1
ENST00000422424.2
family with sequence similarity 96, member B
chr12_-_51717875 23.67 ENST00000604560.1
bridging integrator 2
chr2_-_175499294 23.66 ENST00000392547.2
WAS/WASL interacting protein family, member 1
chr7_-_138794081 23.46 ENST00000464606.1
zinc finger CCCH-type, antiviral 1
chr5_+_271733 23.42 ENST00000264933.4
programmed cell death 6
chr12_-_112856623 23.37 ENST00000551291.2
ribosomal protein L6
chr2_+_201754050 23.25 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr17_-_29641104 23.18 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr19_+_16222439 23.13 ENST00000300935.3
RAB8A, member RAS oncogene family
chr2_-_230786679 23.01 ENST00000543084.1
ENST00000343290.5
ENST00000389044.4
ENST00000283943.5
thyroid hormone receptor interactor 12
chr16_+_50300427 22.94 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
adenylate cyclase 7
chr12_-_51717922 22.89 ENST00000452142.2
bridging integrator 2
chr5_-_150284351 22.82 ENST00000427179.1
zinc finger protein 300
chr7_-_99698338 22.79 ENST00000354230.3
ENST00000425308.1
minichromosome maintenance complex component 7
chr16_+_30484021 22.74 ENST00000358164.5
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr1_-_31230650 22.72 ENST00000294507.3
lysosomal protein transmembrane 5
chr2_+_30369859 22.69 ENST00000402003.3
yippee-like 5 (Drosophila)
chr19_-_10230562 22.67 ENST00000587146.1
ENST00000588709.1
ENST00000253108.4
eukaryotic translation initiation factor 3, subunit G
chr8_+_22437965 22.63 ENST00000409141.1
ENST00000265810.4
PDZ and LIM domain 2 (mystique)
chr10_-_27149904 22.61 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
abl-interactor 1
chr12_+_25205568 22.43 ENST00000548766.1
ENST00000556887.1
lymphoid-restricted membrane protein
chr11_-_64013288 22.43 ENST00000542235.1
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr12_+_25205666 22.40 ENST00000547044.1
lymphoid-restricted membrane protein
chr16_+_30087288 22.37 ENST00000279387.7
ENST00000562664.1
ENST00000562222.1
protein phosphatase 4, catalytic subunit
chrX_+_118602363 22.37 ENST00000317881.8
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr18_+_657733 22.26 ENST00000323250.5
ENST00000323224.7
thymidylate synthetase
chr12_-_51717948 22.23 ENST00000267012.4
bridging integrator 2
chr2_+_143886877 22.18 ENST00000295095.6
Rho GTPase activating protein 15
chr3_-_131221790 22.12 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr19_+_41768401 22.10 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
heterogeneous nuclear ribonucleoprotein U-like 1
chr12_-_112847108 21.89 ENST00000549847.1
ribosomal protein L6
chr19_-_14530143 21.85 ENST00000242776.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr2_-_153573887 21.78 ENST00000493468.2
ENST00000545856.1
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr4_-_103746683 21.77 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr6_-_42016385 21.62 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
cyclin D3
chr11_+_46383121 21.57 ENST00000454345.1
diacylglycerol kinase, zeta
chr19_+_13261216 21.53 ENST00000587885.1
ENST00000292433.3
immediate early response 2
chr2_+_201754135 21.50 ENST00000409357.1
ENST00000409129.2
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr7_+_141438118 21.41 ENST00000265304.6
ENST00000498107.1
ENST00000467681.1
ENST00000465582.1
ENST00000463093.1
single-stranded DNA binding protein 1, mitochondrial
chr14_+_70233810 21.29 ENST00000394366.2
ENST00000553548.1
ENST00000553369.1
ENST00000557154.1
ENST00000451983.2
ENST00000553635.1
serine/arginine-rich splicing factor 5
chr17_+_38278826 20.96 ENST00000577454.1
ENST00000578648.1
ENST00000579565.1
male-specific lethal 1 homolog (Drosophila)
chr1_-_207095324 20.93 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr4_-_103747011 20.81 ENST00000350435.7
ubiquitin-conjugating enzyme E2D 3
chr20_-_45984401 20.80 ENST00000311275.7
zinc finger, MYND-type containing 8
chr3_-_16555150 20.71 ENST00000334133.4
raftlin, lipid raft linker 1
chr3_-_186524234 20.56 ENST00000418288.1
ENST00000296273.2
replication factor C (activator 1) 4, 37kDa
chr15_+_44092784 20.55 ENST00000458412.1
huntingtin interacting protein K
chr3_-_50378343 20.42 ENST00000359365.4
Ras association (RalGDS/AF-6) domain family member 1
chr14_+_102276209 20.38 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
protein phosphatase 2, regulatory subunit B', gamma
chr19_-_10305752 20.37 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNA (cytosine-5-)-methyltransferase 1
chr5_+_110074685 20.30 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr2_+_182321925 20.28 ENST00000339307.4
ENST00000397033.2
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr3_+_184080790 20.27 ENST00000430783.1
polymerase (RNA) II (DNA directed) polypeptide H
chr12_-_108954933 20.22 ENST00000431469.2
ENST00000546815.1
squamous cell carcinoma antigen recognized by T cells 3
chr12_+_7079944 20.18 ENST00000261406.6
EMG1 N1-specific pseudouridine methyltransferase
chr9_-_35103105 20.04 ENST00000452248.2
ENST00000356493.5
stomatin (EPB72)-like 2
chr2_-_235405168 20.01 ENST00000339728.3
ADP-ribosylation factor-like 4C
chr12_-_93835665 19.91 ENST00000552442.1
ENST00000550657.1
ubiquitin-conjugating enzyme E2N
chr19_-_10230540 19.85 ENST00000589454.1
eukaryotic translation initiation factor 3, subunit G
chr20_-_49575058 19.78 ENST00000371584.4
ENST00000371583.5
ENST00000413082.1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr8_-_102217515 19.69 ENST00000520347.1
ENST00000523922.1
ENST00000520984.1
zinc finger protein 706
chr1_-_20987889 19.61 ENST00000415136.2
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr15_-_65809581 19.58 ENST00000341861.5
dipeptidyl-peptidase 8
chr5_-_180236811 19.49 ENST00000446023.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr11_+_237016 19.47 ENST00000352303.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr2_-_174828892 19.43 ENST00000418194.2
Sp3 transcription factor
chr3_-_50378235 19.31 ENST00000357043.2
Ras association (RalGDS/AF-6) domain family member 1
chr14_-_24616426 19.30 ENST00000216802.5
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr10_+_75504105 19.27 ENST00000535742.1
ENST00000546025.1
ENST00000345254.4
ENST00000540668.1
ENST00000339365.2
ENST00000411652.2
SEC24 family member C
chr19_+_9938562 19.25 ENST00000586895.1
ENST00000358666.3
ENST00000590068.1
ENST00000593087.1
ubiquitin-like 5
chr3_-_18480260 19.16 ENST00000454909.2
SATB homeobox 1
chr1_+_111415757 19.10 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr2_+_30369807 19.10 ENST00000379520.3
ENST00000379519.3
ENST00000261353.4
yippee-like 5 (Drosophila)
chr1_-_20987851 19.04 ENST00000464364.1
ENST00000602624.2
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr6_+_111195973 18.98 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
adenosylmethionine decarboxylase 1
chr4_-_103746924 18.95 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
ubiquitin-conjugating enzyme E2D 3
chr17_+_41150793 18.82 ENST00000586277.1
ribosomal protein L27
chr20_+_31407692 18.78 ENST00000375571.5
microtubule-associated protein, RP/EB family, member 1
chr5_+_172410757 18.76 ENST00000519374.1
ENST00000519911.1
ENST00000265093.4
ENST00000517669.1
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
chr1_-_155990580 18.66 ENST00000531917.1
ENST00000480567.1
ENST00000526212.1
ENST00000529008.1
ENST00000496742.1
ENST00000295702.4
signal sequence receptor, beta (translocon-associated protein beta)
chr17_+_41150290 18.61 ENST00000589037.1
ENST00000253788.5
ribosomal protein L27
chr1_+_84944926 18.60 ENST00000370656.1
ENST00000370654.5
ribosome production factor 1 homolog (S. cerevisiae)
chr5_-_140070897 18.58 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
histidyl-tRNA synthetase
chr2_-_231090344 18.54 ENST00000540870.1
ENST00000416610.1
SP110 nuclear body protein
chr18_+_657578 18.50 ENST00000323274.10
thymidylate synthetase
chr4_-_103749179 18.43 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr5_-_40835303 18.39 ENST00000509877.1
ENST00000508493.1
ENST00000274242.5
ribosomal protein L37
chr12_-_120907459 18.29 ENST00000229390.3
serine/arginine-rich splicing factor 9
chr12_-_118797475 18.28 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr17_+_41150479 18.28 ENST00000589913.1
ribosomal protein L27
chr16_+_718086 18.27 ENST00000315082.4
ENST00000563134.1
ras homolog family member T2
chr3_-_10362725 18.27 ENST00000397109.3
ENST00000428626.1
ENST00000445064.1
ENST00000431352.1
ENST00000397117.1
ENST00000337354.4
ENST00000383801.2
ENST00000432213.1
ENST00000350697.3
SEC13 homolog (S. cerevisiae)
chr11_-_64084959 18.16 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr11_+_236540 18.15 ENST00000532097.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr3_+_184081213 18.14 ENST00000429568.1
polymerase (RNA) II (DNA directed) polypeptide H
chr1_+_203830703 18.05 ENST00000414487.2
small nuclear ribonucleoprotein polypeptide E
chr3_+_184081175 18.00 ENST00000452961.1
ENST00000296223.3
polymerase (RNA) II (DNA directed) polypeptide H
chr17_+_43299156 17.94 ENST00000331495.3
formin-like 1
chr17_-_76124812 17.77 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
transmembrane channel-like 6
chr1_+_154947126 17.71 ENST00000368439.1
CDC28 protein kinase regulatory subunit 1B
chrX_+_11777671 17.69 ENST00000380693.3
ENST00000380692.2
male-specific lethal 3 homolog (Drosophila)
chr5_+_167913450 17.64 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chrX_-_153775426 17.57 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr15_-_55489097 17.57 ENST00000260443.4
ribosomal L24 domain containing 1
chr17_-_56595196 17.48 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
myotubularin related protein 4
chr1_-_183559693 17.46 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
neutrophil cytosolic factor 2
chr5_-_169725231 17.44 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr22_+_21921994 17.39 ENST00000545681.1
ubiquitin-conjugating enzyme E2L 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ETS1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
20.3 61.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
19.0 57.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
17.6 52.8 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
13.5 54.0 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
12.5 12.5 GO:2000395 ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
12.0 48.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
12.0 12.0 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
11.8 58.8 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
11.7 70.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
11.2 56.2 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
10.8 43.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
10.7 75.0 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
10.2 51.0 GO:0075525 viral translational termination-reinitiation(GO:0075525)
10.0 20.0 GO:0032456 endocytic recycling(GO:0032456)
9.6 57.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
9.2 54.9 GO:0046070 dGTP metabolic process(GO:0046070)
9.1 9.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
9.1 36.5 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
9.0 27.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
9.0 143.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
8.9 53.6 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
8.5 51.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
8.4 25.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
8.3 33.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
8.2 32.9 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
8.1 40.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
8.0 31.9 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
7.6 30.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
7.5 60.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
7.4 66.3 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
7.3 21.9 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
7.3 21.8 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
7.1 28.3 GO:0030242 pexophagy(GO:0030242)
7.0 21.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
6.9 34.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
6.6 32.9 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
6.6 65.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
6.5 32.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
6.3 19.0 GO:1903970 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
6.3 19.0 GO:0006597 spermine biosynthetic process(GO:0006597)
6.3 18.8 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
6.2 24.7 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
6.1 24.5 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
6.1 18.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
6.1 24.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
6.0 42.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
5.9 17.8 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
5.9 29.3 GO:0019348 dolichol metabolic process(GO:0019348)
5.9 17.6 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
5.8 29.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
5.8 23.2 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
5.7 28.3 GO:0097338 response to clozapine(GO:0097338)
5.6 22.3 GO:1904379 maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
5.6 16.7 GO:1901873 regulation of post-translational protein modification(GO:1901873)
5.4 26.9 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
5.3 85.5 GO:0043248 proteasome assembly(GO:0043248)
5.3 31.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
5.3 10.5 GO:0061010 gall bladder development(GO:0061010)
5.2 41.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
5.2 5.2 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
5.1 25.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
5.0 70.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
5.0 20.0 GO:0090296 regulation of mitochondrial DNA replication(GO:0090296)
5.0 14.9 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
4.8 14.4 GO:0002084 protein depalmitoylation(GO:0002084)
4.8 4.8 GO:0070341 fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344) negative regulation of fat cell proliferation(GO:0070345)
4.8 14.3 GO:1902463 protein localization to cell leading edge(GO:1902463)
4.8 14.3 GO:0039650 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
4.7 4.7 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
4.7 14.1 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
4.6 83.7 GO:0035855 megakaryocyte development(GO:0035855)
4.6 18.3 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
4.6 22.8 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
4.6 45.6 GO:0051096 positive regulation of helicase activity(GO:0051096)
4.5 94.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
4.5 45.0 GO:0018202 peptidyl-histidine modification(GO:0018202)
4.4 8.9 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
4.4 13.2 GO:0006624 vacuolar protein processing(GO:0006624)
4.4 17.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
4.3 38.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
4.3 17.2 GO:0032218 riboflavin transport(GO:0032218)
4.3 17.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
4.1 78.4 GO:0051014 actin filament severing(GO:0051014)
4.1 20.6 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
4.0 52.5 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
4.0 84.1 GO:0097320 membrane tubulation(GO:0097320)
3.9 39.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
3.9 31.2 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
3.9 31.0 GO:0002457 T cell antigen processing and presentation(GO:0002457)
3.9 19.3 GO:0042631 cellular response to water deprivation(GO:0042631)
3.8 56.8 GO:0071044 histone mRNA catabolic process(GO:0071044)
3.8 11.3 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
3.8 11.3 GO:0030327 prenylated protein catabolic process(GO:0030327)
3.8 11.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
3.7 22.4 GO:1901029 adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
3.7 48.1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
3.7 11.1 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
3.7 22.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
3.6 21.9 GO:0060701 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
3.6 29.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
3.5 10.6 GO:0051697 protein delipidation(GO:0051697)
3.5 35.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
3.5 24.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
3.5 14.0 GO:0006382 adenosine to inosine editing(GO:0006382)
3.5 3.5 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
3.5 20.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
3.5 3.5 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
3.4 3.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
3.4 20.2 GO:0070475 rRNA base methylation(GO:0070475)
3.3 46.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
3.2 12.7 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
3.2 12.6 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
3.1 153.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
3.1 31.0 GO:0007000 nucleolus organization(GO:0007000)
3.1 141.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
3.0 12.0 GO:1901895 positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
2.9 8.8 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
2.9 2.9 GO:0021997 neural plate axis specification(GO:0021997)
2.9 23.0 GO:0071569 protein ufmylation(GO:0071569)
2.8 11.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
2.8 17.0 GO:0070560 protein secretion by platelet(GO:0070560)
2.8 16.8 GO:0051013 microtubule severing(GO:0051013)
2.8 11.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
2.8 11.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
2.8 50.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
2.8 5.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
2.8 33.1 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
2.8 11.0 GO:0043555 regulation of translation in response to stress(GO:0043555)
2.7 11.0 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
2.7 55.9 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
2.6 18.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
2.6 10.5 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
2.6 10.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
2.6 7.8 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.6 116.0 GO:0036260 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
2.6 7.7 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
2.6 7.7 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
2.6 12.8 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
2.5 10.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
2.5 7.6 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
2.5 50.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
2.5 2.5 GO:0006404 RNA import into nucleus(GO:0006404)
2.5 12.5 GO:0071895 odontoblast differentiation(GO:0071895)
2.5 19.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
2.5 14.9 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
2.5 7.4 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
2.4 19.5 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
2.4 12.1 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
2.4 7.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
2.4 7.1 GO:0051684 maintenance of Golgi location(GO:0051684)
2.4 106.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
2.4 7.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
2.4 73.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
2.3 11.6 GO:1902410 mitotic cytokinetic process(GO:1902410)
2.3 6.9 GO:1901355 response to rapamycin(GO:1901355)
2.3 34.2 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
2.2 24.6 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
2.2 6.7 GO:0070837 dehydroascorbic acid transport(GO:0070837)
2.2 6.7 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
2.2 201.3 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
2.2 15.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
2.2 4.3 GO:0001923 B-1 B cell differentiation(GO:0001923)
2.1 30.0 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
2.1 21.2 GO:0048290 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
2.1 114.3 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
2.1 6.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
2.1 48.6 GO:0043101 purine-containing compound salvage(GO:0043101)
2.1 16.9 GO:0006348 chromatin silencing at telomere(GO:0006348)
2.1 14.6 GO:0006983 ER overload response(GO:0006983)
2.1 8.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
2.1 49.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
2.0 36.7 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
2.0 89.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
2.0 4.0 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
2.0 26.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
2.0 24.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
2.0 17.9 GO:0002418 immune response to tumor cell(GO:0002418)
2.0 11.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.0 7.9 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
2.0 19.7 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
2.0 25.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
1.9 15.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
1.9 9.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
1.9 1.9 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
1.9 7.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
1.9 11.5 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
1.9 87.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
1.9 5.7 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.9 13.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
1.9 13.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
1.8 23.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.8 23.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
1.8 5.5 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
1.8 12.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.8 1.8 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.8 14.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.8 15.8 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
1.7 1.7 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
1.7 12.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
1.7 5.2 GO:0090135 actin filament branching(GO:0090135)
1.7 3.4 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
1.7 34.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.7 6.6 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
1.6 8.2 GO:0002634 regulation of germinal center formation(GO:0002634)
1.6 16.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
1.6 8.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.6 8.0 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
1.6 4.8 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
1.6 9.5 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
1.6 10.9 GO:1903715 regulation of aerobic respiration(GO:1903715)
1.5 13.8 GO:0071763 nuclear membrane organization(GO:0071763)
1.5 33.5 GO:0006465 signal peptide processing(GO:0006465)
1.5 24.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
1.5 4.5 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
1.5 23.9 GO:0000338 protein deneddylation(GO:0000338)
1.5 19.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.5 19.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
1.5 32.5 GO:0033120 positive regulation of RNA splicing(GO:0033120)
1.5 200.6 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
1.5 5.9 GO:0071802 negative regulation of podosome assembly(GO:0071802)
1.4 38.9 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
1.4 61.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
1.4 4.3 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.4 11.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.4 11.4 GO:1902969 mitotic DNA replication(GO:1902969)
1.4 4.2 GO:0071500 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) cellular response to nitrosative stress(GO:0071500)
1.4 19.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
1.4 5.5 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.4 15.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.4 5.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
1.4 9.5 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
1.3 13.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
1.3 116.2 GO:0006903 vesicle targeting(GO:0006903)
1.3 70.4 GO:0021762 substantia nigra development(GO:0021762)
1.3 75.6 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
1.3 17.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
1.3 11.7 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.3 14.0 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
1.3 105.3 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
1.2 13.7 GO:0051601 exocyst localization(GO:0051601)
1.2 20.0 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
1.2 17.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
1.2 22.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
1.2 9.9 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
1.2 12.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
1.2 2.4 GO:0080009 mRNA methylation(GO:0080009)
1.2 7.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
1.2 14.6 GO:0051382 kinetochore assembly(GO:0051382)
1.2 21.8 GO:0035641 locomotory exploration behavior(GO:0035641)
1.2 14.5 GO:0030238 male sex determination(GO:0030238)
1.2 2.4 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.2 6.0 GO:0007172 signal complex assembly(GO:0007172)
1.2 3.6 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
1.2 39.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.2 4.7 GO:1901804 glucosylceramide catabolic process(GO:0006680) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
1.2 4.7 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
1.2 4.7 GO:0046477 glycosylceramide catabolic process(GO:0046477)
1.2 35.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.2 6.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.1 4.5 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
1.1 7.9 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
1.1 10.0 GO:0009249 protein lipoylation(GO:0009249)
1.1 11.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
1.1 18.7 GO:0008053 mitochondrial fusion(GO:0008053)
1.1 1.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
1.1 42.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
1.1 10.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.1 78.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.1 9.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
1.1 32.2 GO:0035066 positive regulation of histone acetylation(GO:0035066)
1.1 3.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.1 28.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
1.0 7.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
1.0 30.0 GO:0090383 phagosome acidification(GO:0090383)
1.0 4.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
1.0 15.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
1.0 20.3 GO:0007202 activation of phospholipase C activity(GO:0007202)
1.0 27.8 GO:0045948 positive regulation of translational initiation(GO:0045948)
1.0 12.7 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
1.0 89.6 GO:0006413 translational initiation(GO:0006413)
1.0 19.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
1.0 10.5 GO:0045116 protein neddylation(GO:0045116)
1.0 7.6 GO:0035897 proteolysis in other organism(GO:0035897)
0.9 12.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.9 84.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.9 6.5 GO:0046836 glycolipid transport(GO:0046836)
0.9 16.6 GO:0016180 snRNA processing(GO:0016180)
0.9 8.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.9 19.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.9 10.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.9 9.1 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.9 10.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.9 15.2 GO:2001204 regulation of osteoclast development(GO:2001204)
0.9 8.9 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.9 5.2 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.9 4.3 GO:0046203 spermidine catabolic process(GO:0046203)
0.9 5.1 GO:0018343 protein farnesylation(GO:0018343)
0.8 22.9 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.8 30.5 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.8 19.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.8 47.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.8 6.6 GO:0001783 B cell apoptotic process(GO:0001783)
0.8 2.4 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.8 14.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.8 14.8 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.8 0.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.7 3.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.7 12.6 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.7 5.9 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.7 9.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.7 10.8 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.7 3.5 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.7 2.1 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.7 2.7 GO:0006868 glutamine transport(GO:0006868)
0.7 3.4 GO:0034378 chylomicron assembly(GO:0034378)
0.7 12.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.7 22.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.7 9.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.7 11.2 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.7 3.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.7 10.5 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.6 33.7 GO:0048278 vesicle docking(GO:0048278)
0.6 12.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.6 1.9 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.6 11.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.6 9.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.6 0.6 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.6 5.4 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.6 24.0 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.6 7.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.6 29.8 GO:0042100 B cell proliferation(GO:0042100)
0.6 1.8 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.6 6.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.6 9.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.6 17.8 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.5 1.1 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.5 9.3 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.5 6.5 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.5 12.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.5 3.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 3.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.5 2.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.5 8.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.5 3.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.5 8.0 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.5 27.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.5 18.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.5 3.3 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.5 30.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.5 1.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.5 16.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.5 2.7 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.4 14.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.4 15.9 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.4 0.9 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146)
0.4 3.0 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 11.0 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.4 29.0 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.4 3.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.4 3.2 GO:0000012 single strand break repair(GO:0000012)
0.4 1.6 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.4 6.2 GO:0018345 protein palmitoylation(GO:0018345)
0.4 8.1 GO:0007020 microtubule nucleation(GO:0007020)
0.4 3.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.4 27.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 4.6 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.4 2.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.4 2.8 GO:0015074 DNA integration(GO:0015074)
0.3 58.1 GO:0008360 regulation of cell shape(GO:0008360)
0.3 4.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.3 9.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.3 1.3 GO:0072719 cellular response to cisplatin(GO:0072719)
0.3 1.3 GO:0038203 TORC2 signaling(GO:0038203)
0.3 2.2 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.3 6.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.3 1.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.3 131.7 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.3 3.3 GO:0007617 suckling behavior(GO:0001967) mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3 4.2 GO:0006363 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.3 2.7 GO:0002517 T cell tolerance induction(GO:0002517)
0.3 17.5 GO:0006110 regulation of glycolytic process(GO:0006110)
0.3 4.6 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.3 1.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.3 0.8 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.3 3.8 GO:0045055 regulated exocytosis(GO:0045055)
0.3 1.8 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 28.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 1.7 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.2 0.9 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 5.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 1.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.2 2.8 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.2 1.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 2.0 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 2.8 GO:0046686 response to cadmium ion(GO:0046686)
0.2 0.4 GO:0051182 coenzyme transport(GO:0051182)
0.2 9.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 2.9 GO:0060065 uterus development(GO:0060065)
0.2 1.0 GO:0015825 L-serine transport(GO:0015825)
0.2 6.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 3.4 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 7.4 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.9 GO:1903416 response to glycoside(GO:1903416)
0.1 11.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 1.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314) protein K6-linked ubiquitination(GO:0085020)
0.1 5.9 GO:0030183 B cell differentiation(GO:0030183)
0.1 1.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 3.0 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.1 2.3 GO:0001701 in utero embryonic development(GO:0001701)
0.1 0.8 GO:0006013 mannose metabolic process(GO:0006013)
0.1 2.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.6 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 2.9 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.1 2.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.5 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 4.2 GO:0030282 bone mineralization(GO:0030282)
0.1 6.1 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.1 1.8 GO:0033198 response to ATP(GO:0033198)
0.1 0.2 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1 1.9 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.1 0.9 GO:0033619 membrane protein proteolysis(GO:0033619)
0.1 1.8 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 0.4 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 2.4 GO:0055078 sodium ion homeostasis(GO:0055078)
0.1 1.0 GO:0008542 visual learning(GO:0008542)
0.1 5.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 2.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.7 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 2.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 1.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 1.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.8 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0 1.2 GO:0045471 response to ethanol(GO:0045471)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.8 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
23.4 140.6 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
15.0 30.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
13.3 79.9 GO:0071817 MMXD complex(GO:0071817)
13.0 39.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
12.0 48.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
10.4 114.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
10.3 41.3 GO:0071001 U4/U6 snRNP(GO:0071001)
9.9 88.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
9.8 29.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
9.7 29.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
8.1 48.6 GO:1902560 GMP reductase complex(GO:1902560)
7.8 78.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
7.7 85.2 GO:0005688 U6 snRNP(GO:0005688)
7.5 22.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
7.2 86.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
6.8 116.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
6.8 47.6 GO:0072487 MSL complex(GO:0072487)
6.7 53.4 GO:0005683 U7 snRNP(GO:0005683)
6.4 25.7 GO:0070985 TFIIK complex(GO:0070985)
6.2 124.8 GO:0001891 phagocytic cup(GO:0001891)
6.2 18.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
6.0 18.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
5.8 17.4 GO:0036398 TCR signalosome(GO:0036398)
5.8 98.4 GO:0043020 NADPH oxidase complex(GO:0043020)
5.7 17.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
5.7 17.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
5.6 22.3 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
5.5 16.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
5.4 16.2 GO:0071159 NF-kappaB complex(GO:0071159)
5.4 16.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
5.3 10.6 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
5.3 31.5 GO:0070545 PeBoW complex(GO:0070545)
5.1 15.2 GO:0070435 Shc-EGFR complex(GO:0070435)
4.9 108.5 GO:0005838 proteasome regulatory particle(GO:0005838)
4.8 4.8 GO:1990111 spermatoproteasome complex(GO:1990111)
4.8 33.5 GO:0005787 signal peptidase complex(GO:0005787)
4.7 33.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
4.7 9.3 GO:0042627 chylomicron(GO:0042627)
4.5 81.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
4.5 103.5 GO:0030127 COPII vesicle coat(GO:0030127)
4.3 55.7 GO:0097433 dense body(GO:0097433)
4.3 29.8 GO:0005956 protein kinase CK2 complex(GO:0005956)
4.2 29.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
4.1 48.9 GO:0030008 TRAPP complex(GO:0030008)
4.1 20.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
4.0 52.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
3.9 220.5 GO:0001772 immunological synapse(GO:0001772)
3.8 23.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
3.7 18.3 GO:0042643 actomyosin, actin portion(GO:0042643)
3.6 14.3 GO:0000799 nuclear condensin complex(GO:0000799)
3.5 38.6 GO:0070765 gamma-secretase complex(GO:0070765)
3.5 20.9 GO:0008537 proteasome activator complex(GO:0008537)
3.4 13.8 GO:0032044 DSIF complex(GO:0032044)
3.4 30.9 GO:0034709 methylosome(GO:0034709)
3.4 20.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
3.4 23.9 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
3.4 128.1 GO:0030125 clathrin vesicle coat(GO:0030125)
3.4 16.8 GO:0032021 NELF complex(GO:0032021)
3.3 13.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
3.2 41.5 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
3.2 51.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
3.1 12.6 GO:0044611 nuclear pore inner ring(GO:0044611)
3.0 6.1 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
2.9 29.0 GO:0034719 SMN-Sm protein complex(GO:0034719)
2.8 11.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
2.8 14.0 GO:0032009 early phagosome(GO:0032009)
2.8 11.1 GO:0097422 tubular endosome(GO:0097422)
2.7 19.0 GO:0019815 B cell receptor complex(GO:0019815)
2.6 21.0 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
2.5 17.6 GO:0032584 growth cone membrane(GO:0032584)
2.5 22.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
2.4 4.9 GO:0042382 paraspeckles(GO:0042382)
2.4 267.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
2.4 12.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
2.4 7.1 GO:0097441 basilar dendrite(GO:0097441)
2.4 23.7 GO:0042101 T cell receptor complex(GO:0042101)
2.4 19.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
2.4 14.1 GO:0097208 alveolar lamellar body(GO:0097208)
2.3 39.5 GO:0032059 bleb(GO:0032059)
2.3 15.8 GO:0005905 clathrin-coated pit(GO:0005905)
2.3 33.8 GO:0005686 U2 snRNP(GO:0005686)
2.2 6.6 GO:0072589 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
2.2 15.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
2.1 21.4 GO:0097255 R2TP complex(GO:0097255)
2.1 20.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
2.0 11.9 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
2.0 9.9 GO:0044308 axonal spine(GO:0044308)
2.0 5.9 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
2.0 7.8 GO:0070876 SOSS complex(GO:0070876)
1.9 44.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.9 24.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.9 5.7 GO:0034455 t-UTP complex(GO:0034455)
1.9 28.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.9 28.1 GO:0005641 nuclear envelope lumen(GO:0005641)
1.9 13.0 GO:0031415 NatA complex(GO:0031415)
1.8 5.5 GO:0030016 myofibril(GO:0030016)
1.8 5.5 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.8 5.5 GO:0000346 transcription export complex(GO:0000346)
1.8 123.2 GO:0035577 azurophil granule membrane(GO:0035577)
1.8 12.3 GO:0044194 cytolytic granule(GO:0044194)
1.8 22.8 GO:0042555 MCM complex(GO:0042555)
1.7 3.5 GO:0055087 Ski complex(GO:0055087)
1.7 5.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
1.6 13.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.6 11.4 GO:0036021 endolysosome lumen(GO:0036021)
1.6 11.4 GO:0030870 Mre11 complex(GO:0030870)
1.6 14.5 GO:0030126 COPI vesicle coat(GO:0030126)
1.6 11.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.6 11.0 GO:0000813 ESCRT I complex(GO:0000813)
1.6 155.7 GO:0035578 azurophil granule lumen(GO:0035578)
1.6 25.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.6 12.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.6 18.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.6 20.3 GO:0031209 SCAR complex(GO:0031209)
1.6 6.2 GO:0043203 axon hillock(GO:0043203)
1.5 13.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
1.5 15.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
1.5 21.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
1.5 11.8 GO:0032133 chromosome passenger complex(GO:0032133)
1.5 17.6 GO:0097431 mitotic spindle pole(GO:0097431)
1.4 12.9 GO:0072546 ER membrane protein complex(GO:0072546)
1.4 10.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.4 10.9 GO:0000322 storage vacuole(GO:0000322)
1.4 31.1 GO:0071141 SMAD protein complex(GO:0071141)
1.3 77.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.3 30.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.3 129.6 GO:0017053 transcriptional repressor complex(GO:0017053)
1.3 15.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
1.3 12.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.2 8.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
1.2 6.0 GO:0071439 clathrin complex(GO:0071439)
1.2 20.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.1 43.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
1.1 12.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.1 3.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
1.1 13.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
1.1 6.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.1 11.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.1 4.3 GO:0032449 CBM complex(GO:0032449)
1.1 23.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
1.0 54.3 GO:0043198 dendritic shaft(GO:0043198)
1.0 16.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.0 1.9 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.9 7.5 GO:1902911 protein kinase complex(GO:1902911)
0.9 12.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.9 16.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.9 2.7 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.9 70.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.9 3.6 GO:0033263 CORVET complex(GO:0033263)
0.9 11.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.9 3.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.9 12.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.8 32.0 GO:0002102 podosome(GO:0002102)
0.8 124.6 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.8 46.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.8 17.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.8 50.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.8 3.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.8 3.2 GO:0016580 Sin3 complex(GO:0016580)
0.8 14.3 GO:0097342 ripoptosome(GO:0097342)
0.8 23.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.8 14.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.8 41.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.8 323.3 GO:0016607 nuclear speck(GO:0016607)
0.8 6.8 GO:0030897 HOPS complex(GO:0030897)
0.7 5.2 GO:0016600 flotillin complex(GO:0016600)
0.7 20.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.7 8.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.7 19.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.7 9.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.7 28.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.7 11.0 GO:0030904 retromer complex(GO:0030904)
0.7 17.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.7 8.7 GO:0005839 proteasome core complex(GO:0005839)
0.6 21.4 GO:0005768 endosome(GO:0005768)
0.6 2.5 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.6 3.8 GO:0005675 core TFIIH complex(GO:0000439) holo TFIIH complex(GO:0005675)
0.6 6.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.6 20.5 GO:0008180 COP9 signalosome(GO:0008180)
0.6 5.5 GO:0000242 pericentriolar material(GO:0000242)
0.6 17.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.6 22.6 GO:0045171 intercellular bridge(GO:0045171)
0.6 10.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.6 7.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.6 4.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.6 5.2 GO:0042588 zymogen granule(GO:0042588)
0.6 18.5 GO:0090544 BAF-type complex(GO:0090544)
0.6 48.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.6 2.9 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.6 4.0 GO:0032039 integrator complex(GO:0032039)
0.6 28.1 GO:0031201 SNARE complex(GO:0031201)
0.5 3.3 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.5 5.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5 3.6 GO:0017119 Golgi transport complex(GO:0017119)
0.5 36.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.5 3.0 GO:0061700 GATOR2 complex(GO:0061700)
0.5 3.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 58.6 GO:0005795 Golgi stack(GO:0005795)
0.5 7.8 GO:0036452 ESCRT complex(GO:0036452)
0.5 3.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.5 5.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.4 6.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.4 8.8 GO:0035861 site of double-strand break(GO:0035861)
0.4 16.3 GO:0035579 specific granule membrane(GO:0035579)
0.4 7.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.4 4.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 4.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 18.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.3 3.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 2.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.3 1.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.3 1.6 GO:1990130 Iml1 complex(GO:1990130)
0.3 17.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.3 1.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.3 8.1 GO:0099738 cell cortex region(GO:0099738)
0.3 3.9 GO:0000145 exocyst(GO:0000145)
0.3 17.4 GO:0005840 ribosome(GO:0005840)
0.3 3.7 GO:0031105 septin complex(GO:0031105)
0.3 41.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 31.1 GO:0005911 cell-cell junction(GO:0005911)
0.2 7.6 GO:0005811 lipid particle(GO:0005811)
0.2 4.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 5.3 GO:0032040 small-subunit processome(GO:0032040)
0.2 0.7 GO:1990393 3M complex(GO:1990393)
0.2 10.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 12.1 GO:0032587 ruffle membrane(GO:0032587)
0.2 44.3 GO:0072562 blood microparticle(GO:0072562)
0.2 6.2 GO:0031901 early endosome membrane(GO:0031901)
0.2 4.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 0.6 GO:0070939 Dsl1p complex(GO:0070939)
0.2 44.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.2 50.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 15.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.2 8.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 29.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.2 52.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 15.4 GO:0036064 ciliary basal body(GO:0036064)
0.2 1.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 1.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 3.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 4.0 GO:0000791 euchromatin(GO:0000791)
0.1 8.9 GO:0030175 filopodium(GO:0030175)
0.1 2.2 GO:0097228 sperm principal piece(GO:0097228)
0.1 12.4 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 3.2 GO:0098797 plasma membrane protein complex(GO:0098797)
0.1 137.2 GO:0070062 extracellular exosome(GO:0070062)
0.1 8.0 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
20.1 140.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
16.2 64.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
15.4 107.7 GO:0030621 U4 snRNA binding(GO:0030621)
13.9 83.4 GO:0042610 CD8 receptor binding(GO:0042610)
13.2 92.2 GO:0050815 phosphoserine binding(GO:0050815)
11.6 11.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
11.2 33.5 GO:0004917 interleukin-7 receptor activity(GO:0004917)
10.8 32.3 GO:0031859 platelet activating factor receptor binding(GO:0031859)
9.8 29.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
9.4 103.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
9.1 27.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
8.2 32.9 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
8.1 48.6 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
7.7 23.2 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
7.5 29.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
7.3 21.8 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
7.1 35.3 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
6.2 18.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
6.2 18.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
6.2 135.3 GO:0000339 RNA cap binding(GO:0000339)
5.9 17.6 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
5.6 22.4 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
5.3 31.7 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
5.3 105.0 GO:0032794 GTPase activating protein binding(GO:0032794)
5.2 62.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
5.2 31.1 GO:0035500 MH2 domain binding(GO:0035500)
5.2 10.3 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
5.0 30.0 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
5.0 14.9 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
4.9 4.9 GO:0004532 3'-5'-exoribonuclease activity(GO:0000175) exonuclease activity(GO:0004527) exoribonuclease activity(GO:0004532) 3'-5' exonuclease activity(GO:0008408) exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016796) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
4.8 29.0 GO:0042296 ISG15 transferase activity(GO:0042296)
4.8 14.3 GO:0097677 STAT family protein binding(GO:0097677)
4.7 4.7 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
4.7 51.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
4.6 73.3 GO:0008179 adenylate cyclase binding(GO:0008179)
4.5 81.7 GO:0001054 RNA polymerase I activity(GO:0001054)
4.5 13.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
4.4 87.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
4.3 95.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
4.3 17.2 GO:0032217 riboflavin transporter activity(GO:0032217)
4.2 21.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
4.1 24.7 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
4.0 19.9 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
3.9 19.5 GO:0043120 tumor necrosis factor binding(GO:0043120)
3.9 27.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
3.8 26.8 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
3.8 11.4 GO:0030984 kininogen binding(GO:0030984)
3.7 14.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
3.7 40.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
3.7 66.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
3.6 21.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
3.4 23.9 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
3.4 47.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
3.4 47.3 GO:0030957 Tat protein binding(GO:0030957)
3.4 108.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
3.3 50.1 GO:0005522 profilin binding(GO:0005522)
3.3 55.6 GO:0043495 protein anchor(GO:0043495)
3.1 78.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
3.1 9.4 GO:0045322 unmethylated CpG binding(GO:0045322)
3.1 24.8 GO:1990405 protein antigen binding(GO:1990405)
3.1 49.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
3.0 24.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
3.0 129.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
3.0 12.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
3.0 20.9 GO:0061133 endopeptidase activator activity(GO:0061133)
2.9 8.8 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
2.9 26.5 GO:0070990 snRNP binding(GO:0070990)
2.9 20.6 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.9 31.8 GO:0015266 protein channel activity(GO:0015266)
2.9 8.6 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
2.9 14.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
2.8 11.4 GO:0043515 kinetochore binding(GO:0043515)
2.8 11.3 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
2.8 75.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.8 16.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
2.8 11.1 GO:0016748 succinyltransferase activity(GO:0016748)
2.7 16.4 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
2.7 21.9 GO:0070087 chromo shadow domain binding(GO:0070087)
2.7 2.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
2.7 24.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
2.6 7.8 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
2.6 49.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.6 38.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
2.6 5.2 GO:0032427 GBD domain binding(GO:0032427)
2.5 20.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
2.4 12.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
2.4 16.8 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
2.4 7.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
2.4 21.2 GO:0043426 MRF binding(GO:0043426)
2.3 9.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
2.3 9.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
2.2 20.0 GO:1901612 cardiolipin binding(GO:1901612)
2.2 6.7 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
2.2 17.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
2.0 16.2 GO:0097100 supercoiled DNA binding(GO:0097100)
2.0 12.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
1.9 7.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.9 9.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
1.9 5.7 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.9 11.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.9 96.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.8 97.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.8 5.5 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
1.8 45.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.8 14.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.8 12.5 GO:0004673 protein histidine kinase activity(GO:0004673)
1.8 7.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.8 116.6 GO:0003743 translation initiation factor activity(GO:0003743)
1.8 21.2 GO:0031386 protein tag(GO:0031386)
1.7 80.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
1.7 3.5 GO:0016361 activin receptor activity, type I(GO:0016361)
1.7 22.4 GO:0003680 AT DNA binding(GO:0003680)
1.7 30.9 GO:0070628 proteasome binding(GO:0070628)
1.7 5.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
1.7 11.8 GO:0035174 histone serine kinase activity(GO:0035174)
1.7 37.0 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.7 21.8 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
1.6 6.5 GO:0017089 glycolipid transporter activity(GO:0017089)
1.6 32.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.6 23.8 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
1.6 19.0 GO:0089720 caspase binding(GO:0089720)
1.6 11.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.6 37.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
1.6 45.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
1.6 17.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.5 13.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.5 27.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.5 24.5 GO:0070064 proline-rich region binding(GO:0070064)
1.5 19.8 GO:0050786 RAGE receptor binding(GO:0050786)
1.5 12.1 GO:0008097 5S rRNA binding(GO:0008097)
1.5 4.5 GO:0015235 cobalamin transporter activity(GO:0015235)
1.5 11.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
1.4 4.3 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
1.4 10.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.4 30.9 GO:0008327 methyl-CpG binding(GO:0008327)
1.4 33.5 GO:0070403 NAD+ binding(GO:0070403)
1.4 6.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.4 8.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
1.3 9.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
1.3 18.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.3 9.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.3 85.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
1.3 5.1 GO:0001849 complement component C1q binding(GO:0001849)
1.3 20.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
1.3 268.4 GO:0003735 structural constituent of ribosome(GO:0003735)
1.3 10.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
1.3 18.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.2 3.7 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
1.2 12.5 GO:0046790 virion binding(GO:0046790)
1.2 22.1 GO:0043422 protein kinase B binding(GO:0043422)
1.2 3.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.2 7.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
1.2 7.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.2 23.6 GO:0008266 poly(U) RNA binding(GO:0008266)
1.2 8.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.2 4.7 GO:0004348 glucosylceramidase activity(GO:0004348)
1.2 4.7 GO:0016936 galactoside binding(GO:0016936)
1.2 27.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
1.1 15.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
1.1 55.9 GO:0017080 sodium channel regulator activity(GO:0017080)
1.1 6.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.1 11.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.1 21.7 GO:0005521 lamin binding(GO:0005521)
1.1 22.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
1.1 30.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.1 12.8 GO:0017070 U6 snRNA binding(GO:0017070)
1.0 16.6 GO:0019992 diacylglycerol binding(GO:0019992)
1.0 5.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.0 42.8 GO:0050699 WW domain binding(GO:0050699)
1.0 3.0 GO:0005174 CD40 receptor binding(GO:0005174)
1.0 3.0 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
1.0 22.9 GO:0004383 guanylate cyclase activity(GO:0004383)
1.0 9.9 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
1.0 6.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.0 6.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.9 35.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.9 7.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.9 23.6 GO:0001671 ATPase activator activity(GO:0001671)
0.9 12.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.9 4.5 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.9 8.9 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.9 14.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.9 2.6 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.8 22.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.8 25.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.8 15.8 GO:0051400 BH domain binding(GO:0051400)
0.8 4.2 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.8 25.7 GO:0042169 SH2 domain binding(GO:0042169)
0.8 19.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.8 7.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.8 13.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.8 17.8 GO:0008242 omega peptidase activity(GO:0008242)
0.8 35.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.8 32.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.8 178.8 GO:0051015 actin filament binding(GO:0051015)
0.8 11.8 GO:0019843 rRNA binding(GO:0019843)
0.8 18.7 GO:0031489 myosin V binding(GO:0031489)
0.8 10.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.8 10.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.8 10.5 GO:0004697 protein kinase C activity(GO:0004697)
0.7 3.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.7 16.2 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.7 8.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.7 10.3 GO:0043274 phospholipase binding(GO:0043274)
0.7 10.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.7 2.9 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.7 2.9 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
0.7 9.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.7 68.5 GO:0043130 ubiquitin binding(GO:0043130)
0.7 44.7 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.7 4.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.7 110.5 GO:0005178 integrin binding(GO:0005178)
0.7 2.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.7 1.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.7 4.1 GO:0034452 dynactin binding(GO:0034452)
0.7 4.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.7 12.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.7 6.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.7 9.2 GO:0033691 sialic acid binding(GO:0033691)
0.7 7.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.6 1.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.6 61.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.6 34.7 GO:0035064 methylated histone binding(GO:0035064)
0.6 12.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.6 10.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.6 2.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.6 16.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.6 10.9 GO:0097602 cullin family protein binding(GO:0097602)
0.6 12.7 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.6 13.8 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.6 4.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.6 5.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.6 1.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.6 21.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.6 10.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.6 6.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.6 21.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.6 1.7 GO:0019237 centromeric DNA binding(GO:0019237)
0.6 11.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.6 32.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.5 30.8 GO:0019003 GDP binding(GO:0019003)
0.5 13.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.5 3.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 11.5 GO:0005525 GTP binding(GO:0005525)
0.5 11.4 GO:0043236 laminin binding(GO:0043236)
0.5 12.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5 6.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.5 4.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.5 3.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.5 1.9 GO:0035325 Toll-like receptor binding(GO:0035325)
0.5 3.8 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.5 21.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.5 4.6 GO:0042287 MHC protein binding(GO:0042287)
0.5 49.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.5 10.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.5 18.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.4 17.7 GO:0042805 actinin binding(GO:0042805)
0.4 11.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.4 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.4 12.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 14.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.4 3.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 6.2 GO:0002039 p53 binding(GO:0002039)
0.4 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 2.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 1.4 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.3 26.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 11.2 GO:0030145 manganese ion binding(GO:0030145)
0.3 1.2 GO:0050692 9-cis retinoic acid receptor activity(GO:0004886) retinoic acid-responsive element binding(GO:0044323) DBD domain binding(GO:0050692)
0.3 1.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.3 22.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.3 7.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.3 1.8 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.3 6.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.3 1.1 GO:0043559 insulin binding(GO:0043559)
0.3 2.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 2.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 0.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 5.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 24.6 GO:0005262 calcium channel activity(GO:0005262)
0.2 15.6 GO:0008276 protein methyltransferase activity(GO:0008276)
0.2 5.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 1.1 GO:0050693 LBD domain binding(GO:0050693)
0.2 15.2 GO:0009055 electron carrier activity(GO:0009055)
0.2 5.2 GO:0015149 hexose transmembrane transporter activity(GO:0015149)
0.2 76.1 GO:0003682 chromatin binding(GO:0003682)
0.2 1.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 0.4 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2 4.8 GO:0004175 endopeptidase activity(GO:0004175)
0.2 1.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 18.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 3.9 GO:0030276 clathrin binding(GO:0030276)
0.2 9.1 GO:0035254 glutamate receptor binding(GO:0035254)
0.2 2.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 61.2 GO:0019900 kinase binding(GO:0019900)
0.2 0.5 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.2 0.6 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 30.6 GO:0003924 GTPase activity(GO:0003924)
0.1 2.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 6.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 9.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 1.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 6.6 GO:0001618 virus receptor activity(GO:0001618)
0.1 4.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 3.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 2.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 1.4 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 0.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 2.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 4.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 6.2 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 4.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.8 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 267.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
4.9 29.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
4.9 162.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
4.7 437.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
3.3 290.7 PID RAC1 PATHWAY RAC1 signaling pathway
3.1 119.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
2.7 70.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
2.2 13.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.9 114.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
1.8 25.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.5 88.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
1.4 33.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.4 54.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.4 38.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
1.4 27.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.4 16.3 PID S1P S1P4 PATHWAY S1P4 pathway
1.2 31.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.1 31.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
1.1 10.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.0 43.7 PID ATR PATHWAY ATR signaling pathway
1.0 28.1 PID IL1 PATHWAY IL1-mediated signaling events
0.9 36.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.9 36.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.9 107.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.9 33.0 PID BCR 5PATHWAY BCR signaling pathway
0.9 26.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.8 17.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.8 49.3 PID P53 REGULATION PATHWAY p53 pathway
0.7 38.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.7 44.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.7 12.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.7 20.6 PID AURORA A PATHWAY Aurora A signaling
0.7 6.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.6 8.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.6 13.2 PID IFNG PATHWAY IFN-gamma pathway
0.6 18.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.6 10.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.5 33.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.4 10.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4 40.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.4 29.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.4 19.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.4 8.9 PID INSULIN PATHWAY Insulin Pathway
0.4 8.0 PID BARD1 PATHWAY BARD1 signaling events
0.4 14.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.3 11.9 PID AURORA B PATHWAY Aurora B signaling
0.3 4.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 9.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 7.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 7.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 8.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 3.5 PID ALK2 PATHWAY ALK2 signaling events
0.2 9.9 PID E2F PATHWAY E2F transcription factor network
0.1 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 4.4 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 3.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 233.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
8.3 49.9 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
7.3 101.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
4.9 73.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
3.8 11.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
3.8 75.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
3.6 118.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
3.5 306.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
3.4 174.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
3.4 82.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
3.4 252.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
3.4 43.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
3.2 54.8 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
3.2 80.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
3.1 49.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.9 128.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
2.9 46.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
2.8 76.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
2.7 41.0 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
2.7 355.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
2.7 104.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
2.7 69.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.6 201.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
2.4 24.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
2.3 114.8 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
2.2 53.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
2.1 44.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
2.0 18.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
2.0 33.8 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
1.9 47.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
1.9 32.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.9 45.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.8 11.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
1.8 8.8 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
1.7 37.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
1.7 18.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.7 26.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.6 35.4 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
1.6 28.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
1.6 54.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.6 192.3 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
1.5 62.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.5 14.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
1.4 45.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
1.4 23.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.4 39.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.3 45.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.3 109.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.3 45.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
1.3 37.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
1.3 32.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
1.3 20.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.2 24.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.2 22.3 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
1.2 33.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.1 5.4 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
1.0 16.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
1.0 22.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.9 33.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.9 23.0 REACTOME TRANSLATION Genes involved in Translation
0.9 125.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.9 50.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.9 28.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.9 15.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.8 19.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.7 6.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.7 15.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.7 119.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.7 14.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.7 25.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.7 13.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.7 10.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.7 4.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.7 30.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.6 15.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6 9.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.6 8.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.5 13.1 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.5 4.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.5 3.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.5 15.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.5 7.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.4 7.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4 1.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.4 12.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 5.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.4 6.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.4 14.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 17.7 REACTOME ACTIVATED TLR4 SIGNALLING Genes involved in Activated TLR4 signalling
0.3 4.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 8.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.3 1.5 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 5.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 1.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 26.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 9.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 2.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.2 4.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 3.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 3.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 6.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 12.8 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.1 2.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 3.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 0.8 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.1 1.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 3.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 4.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling