ISMARA results: ETV1_ERF_FEV

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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ETV1_ERF_FEV_ELF1

Z-value: 2.92

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Transcription factors associated with ETV1_ERF_FEV_ELF1

Gene Symbol	Gene ID	Gene Info
ETV1 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000006468.9	ETS variant transcription factor 1
ERF Ensembl NCBI GeneCards UniProt NextProt	ENSG00000105722.5	ETS2 repressor factor
FEV Ensembl NCBI GeneCards UniProt NextProt	ENSG00000163497.2	FEV transcription factor, ETS family member
ELF1 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000120690.9	E74 like ETS transcription factor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ELF1	hg19_v2_chr13_-_41593425_41593480	-0.72	1.3e-35	Click!
ERF	hg19_v2_chr19_-_42759300_42759324	0.28	3.2e-05	Click!
ETV1	hg19_v2_chr7_-_14026063_14026091	-0.13	6.4e-02	Click!
FEV	hg19_v2_chr2_-_219850277_219850379	-0.01	8.4e-01	Click!

Activity profile of ETV1_ERF_FEV_ELF1 motif

Sorted Z-values of ETV1_ERF_FEV_ELF1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr14_-_69864993 Show fit	130.67	ENST00000555373.1	ERH Ensembl NCBI GeneCards UniProt NextProt Show fit	enhancer of rudimentary homolog (Drosophila)
chr1_-_169337176 Show fit	89.21	ENST00000472647.1 ENST00000367811.3	NME7 Ensembl NCBI GeneCards UniProt NextProt Show fit	NME/NM23 family member 7
chr8_+_145133493 Show fit	72.56	ENST00000316052.5 ENST00000525936.1	EXOSC4 Ensembl NCBI GeneCards UniProt NextProt Show fit	exosome component 4
chr5_-_140070897 Show fit	69.93	ENST00000448240.1 ENST00000438307.2 ENST00000415192.2 ENST00000457527.2 ENST00000307633.3 ENST00000507746.1 ENST00000431330.2	HARS Ensembl NCBI GeneCards UniProt NextProt Show fit	histidyl-tRNA synthetase
chr2_+_177134134 Show fit	68.99	ENST00000249442.6 ENST00000392529.2 ENST00000443241.1	MTX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	metaxin 2
chr2_+_177134201 Show fit	64.11	ENST00000452865.1	MTX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	metaxin 2
chr5_+_892745 Show fit	63.74	ENST00000166345.3	TRIP13 Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 13
chr18_-_812517 Show fit	63.36	ENST00000584307.1	YES1 Ensembl NCBI GeneCards UniProt NextProt Show fit	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr5_+_68530668 Show fit	63.29	ENST00000506563.1	CDK7 Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 7
chr8_+_30300119 Show fit	60.30	ENST00000520191.1	RBPMS Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein with multiple splicing
chr15_+_90808919 Show fit	60.07	ENST00000379095.3	NGRN Ensembl NCBI GeneCards UniProt NextProt Show fit	neugrin, neurite outgrowth associated
chr1_+_154947126 Show fit	59.99	ENST00000368439.1	CKS1B Ensembl NCBI GeneCards UniProt NextProt Show fit	CDC28 protein kinase regulatory subunit 1B
chr18_-_812231 Show fit	56.90	ENST00000314574.4	YES1 Ensembl NCBI GeneCards UniProt NextProt Show fit	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr17_-_57784755 Show fit	55.29	ENST00000537860.1 ENST00000393038.2 ENST00000409433.2	PTRH2 Ensembl NCBI GeneCards UniProt NextProt Show fit	peptidyl-tRNA hydrolase 2
chr8_-_121457332 Show fit	54.39	ENST00000518918.1	MRPL13 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L13
chr11_-_46722117 Show fit	53.82	ENST00000311956.4	ARHGAP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 1
chrX_-_153775426 Show fit	52.71	ENST00000393562.2	G6PD Ensembl NCBI GeneCards UniProt NextProt Show fit	glucose-6-phosphate dehydrogenase
chr1_-_43638168 Show fit	51.77	ENST00000431635.2	EBNA1BP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	EBNA1 binding protein 2
chr5_+_68530697 Show fit	51.28	ENST00000256443.3 ENST00000514676.1	CDK7 Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 7
chr11_+_118889456 Show fit	51.09	ENST00000528230.1 ENST00000525303.1 ENST00000434101.2 ENST00000359005.4 ENST00000533058.1	TRAPPC4 Ensembl NCBI GeneCards UniProt NextProt Show fit	trafficking protein particle complex 4
chr2_-_110371720 Show fit	50.42	ENST00000356688.4	SEPT10 Ensembl NCBI GeneCards UniProt NextProt Show fit	septin 10
chr1_-_43637915 Show fit	48.86	ENST00000236051.2	EBNA1BP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	EBNA1 binding protein 2
chr1_-_43855444 Show fit	48.37	ENST00000372455.4	MED8 Ensembl NCBI GeneCards UniProt NextProt Show fit	mediator complex subunit 8
chr11_+_70244510 Show fit	48.18	ENST00000346329.3 ENST00000301843.8 ENST00000376561.3	CTTN Ensembl NCBI GeneCards UniProt NextProt Show fit	cortactin
chr2_-_110371777 Show fit	46.90	ENST00000397712.2	SEPT10 Ensembl NCBI GeneCards UniProt NextProt Show fit	septin 10
chr12_-_110888103 Show fit	46.82	ENST00000426440.1 ENST00000228825.7	ARPC3 Ensembl NCBI GeneCards UniProt NextProt Show fit	actin related protein 2/3 complex, subunit 3, 21kDa
chr2_-_73964447 Show fit	46.62	ENST00000272424.5 ENST00000409716.2 ENST00000318190.7	TPRKB Ensembl NCBI GeneCards UniProt NextProt Show fit	TP53RK binding protein
chr11_+_118889142 Show fit	46.30	ENST00000533632.1	TRAPPC4 Ensembl NCBI GeneCards UniProt NextProt Show fit	trafficking protein particle complex 4
chr8_-_121457608 Show fit	45.35	ENST00000306185.3	MRPL13 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L13
chr20_-_54967187 Show fit	43.44	ENST00000422322.1 ENST00000371356.2 ENST00000451915.1 ENST00000347343.2 ENST00000395911.1 ENST00000395907.1 ENST00000441357.1 ENST00000456249.1 ENST00000420474.1 ENST00000395909.4 ENST00000395914.1 ENST00000312783.6 ENST00000395915.3 ENST00000395913.3	AURKA Ensembl NCBI GeneCards UniProt NextProt Show fit	aurora kinase A
chr3_-_57583185 Show fit	42.46	ENST00000463880.1	ARF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor 4
chr1_-_1310530 Show fit	42.18	ENST00000338370.3 ENST00000321751.5 ENST00000378853.3	AURKAIP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	aurora kinase A interacting protein 1
chrX_+_51546103 Show fit	41.43	ENST00000375772.3	MAGED1 Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family D, 1
chr7_+_128379346 Show fit	41.36	ENST00000535011.2 ENST00000542996.2 ENST00000535623.1 ENST00000538546.1 ENST00000249364.4 ENST00000449187.2	CALU Ensembl NCBI GeneCards UniProt NextProt Show fit	calumenin
chr11_-_116658695 Show fit	41.14	ENST00000429220.1 ENST00000444935.1	ZNF259 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 259
chr20_-_49575058 Show fit	40.36	ENST00000371584.4 ENST00000371583.5 ENST00000413082.1	DPM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr1_-_1310870 Show fit	40.24	ENST00000338338.5	AURKAIP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	aurora kinase A interacting protein 1
chr7_+_102988082 Show fit	40.09	ENST00000292644.3 ENST00000544811.1	PSMC2 Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr20_+_30327063 Show fit	39.86	ENST00000300403.6 ENST00000340513.4	TPX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	TPX2, microtubule-associated
chr7_+_128379449 Show fit	39.78	ENST00000479257.1	CALU Ensembl NCBI GeneCards UniProt NextProt Show fit	calumenin
chr1_+_32687971 Show fit	39.72	ENST00000373586.1	EIF3I Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3, subunit I
chr12_+_56546363 Show fit	39.56	ENST00000551834.1 ENST00000552568.1	MYL6B Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr5_+_132202252 Show fit	39.21	ENST00000378670.3 ENST00000378667.1 ENST00000378665.1	UQCRQ Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
chr11_-_116658758 Show fit	38.96	ENST00000227322.3	ZNF259 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 259
chr16_-_20817753 Show fit	38.60	ENST00000389345.5 ENST00000300005.3 ENST00000357967.4 ENST00000569729.1	ERI2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ERI1 exoribonuclease family member 2
chr15_+_63340647 Show fit	38.36	ENST00000404484.4	TPM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tropomyosin 1 (alpha)
chr6_-_31926629 Show fit	38.35	ENST00000375425.5 ENST00000426722.1 ENST00000441998.1 ENST00000444811.2 ENST00000375429.3	NELFE Ensembl NCBI GeneCards UniProt NextProt Show fit	negative elongation factor complex member E
chr14_+_75469606 Show fit	37.86	ENST00000266126.5	EIF2B2 Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr16_-_66968265 Show fit	37.55	ENST00000567511.1 ENST00000422424.2	FAM96B Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 96, member B
chr20_-_49575081 Show fit	37.25	ENST00000371588.5 ENST00000371582.4	DPM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr7_-_7680601 Show fit	37.25	ENST00000396682.2	RPA3 Ensembl NCBI GeneCards UniProt NextProt Show fit	replication protein A3, 14kDa
chr15_+_63340858 Show fit	37.14	ENST00000560615.1	TPM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tropomyosin 1 (alpha)
chr6_-_33239712 Show fit	37.10	ENST00000436044.2	VPS52 Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 52 homolog (S. cerevisiae)
chr15_+_63340734 Show fit	37.01	ENST00000560959.1	TPM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tropomyosin 1 (alpha)
chr17_+_7487146 Show fit	36.85	ENST00000396501.4 ENST00000584378.1 ENST00000423172.2 ENST00000579445.1 ENST00000585217.1 ENST00000581380.1	MPDU1 Ensembl NCBI GeneCards UniProt NextProt Show fit	mannose-P-dolichol utilization defect 1
chr16_+_67261008 Show fit	36.82	ENST00000304800.9 ENST00000563953.1 ENST00000565201.1	TMEM208 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 208
chr20_+_43104508 Show fit	36.65	ENST00000262605.4 ENST00000372904.3	TTPAL Ensembl NCBI GeneCards UniProt NextProt Show fit	tocopherol (alpha) transfer protein-like
chr2_+_201754050 Show fit	36.50	ENST00000426253.1 ENST00000416651.1 ENST00000454952.1 ENST00000409020.1 ENST00000359683.4	NIF3L1 Ensembl NCBI GeneCards UniProt NextProt Show fit	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr2_-_9563469 Show fit	36.19	ENST00000484735.1 ENST00000456913.2	ITGB1BP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin beta 1 binding protein 1
chr17_-_4843316 Show fit	35.87	ENST00000544061.2	SLC25A11 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr2_-_110371412 Show fit	35.55	ENST00000415095.1 ENST00000334001.6 ENST00000437928.1 ENST00000493445.1 ENST00000397714.2 ENST00000461295.1	SEPT10 Ensembl NCBI GeneCards UniProt NextProt Show fit	septin 10
chr10_-_15902449 Show fit	35.53	ENST00000277632.3	FAM188A Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 188, member A
chr2_+_201754135 Show fit	35.47	ENST00000409357.1 ENST00000409129.2	NIF3L1 Ensembl NCBI GeneCards UniProt NextProt Show fit	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr12_+_7079944 Show fit	35.31	ENST00000261406.6	EMG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	EMG1 N1-specific pseudouridine methyltransferase
chr14_+_69865401 Show fit	35.17	ENST00000556605.1 ENST00000336643.5 ENST00000031146.4	SLC39A9 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 39, member 9
chr12_+_56546223 Show fit	35.12	ENST00000550443.1 ENST00000207437.5	MYL6B Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr6_+_33257427 Show fit	34.82	ENST00000463584.1	PFDN6 Ensembl NCBI GeneCards UniProt NextProt Show fit	prefoldin subunit 6
chr1_+_38478432 Show fit	34.60	ENST00000537711.1	UTP11L Ensembl NCBI GeneCards UniProt NextProt Show fit	UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr16_-_31085514 Show fit	33.75	ENST00000300849.4	ZNF668 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 668
chr17_+_57784826 Show fit	33.65	ENST00000262291.4	VMP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuole membrane protein 1
chr5_+_140739537 Show fit	33.55	ENST00000522605.1	PCDHGB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin gamma subfamily B, 2
chr5_+_140071178 Show fit	33.44	ENST00000508522.1 ENST00000448069.2	HARS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	histidyl-tRNA synthetase 2, mitochondrial
chr19_+_19627026 Show fit	33.38	ENST00000608404.1 ENST00000555938.1 ENST00000503283.1 ENST00000512771.3 ENST00000428459.2	YJEFN3 Ensembl NCBI GeneCards UniProt NextProt Show fit CTC-260F20.3 Ensembl NCBI GeneCards UniProt NextProt Show fit NDUFA13 Ensembl NCBI GeneCards UniProt NextProt Show fit	YjeF N-terminal domain containing 3 Uncharacterized protein NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr11_-_6502580 Show fit	33.30	ENST00000423813.2 ENST00000396777.3	ARFIP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor interacting protein 2
chr3_-_48481434 Show fit	33.07	ENST00000395694.2 ENST00000447018.1 ENST00000442740.1	CCDC51 Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 51
chr1_+_38478378 Show fit	32.40	ENST00000373014.4	UTP11L Ensembl NCBI GeneCards UniProt NextProt Show fit	UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr2_-_110371664 Show fit	32.38	ENST00000545389.1 ENST00000423520.1	SEPT10 Ensembl NCBI GeneCards UniProt NextProt Show fit	septin 10
chr17_-_19281203 Show fit	32.29	ENST00000487415.2	B9D1 Ensembl NCBI GeneCards UniProt NextProt Show fit	B9 protein domain 1
chr17_+_37844331 Show fit	32.18	ENST00000578199.1 ENST00000406381.2	ERBB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr11_-_6502534 Show fit	31.84	ENST00000254584.2 ENST00000525235.1 ENST00000445086.2	ARFIP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor interacting protein 2
chr3_-_48481518 Show fit	31.77	ENST00000412398.2 ENST00000395696.1	CCDC51 Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 51
chr16_-_66968055 Show fit	31.68	ENST00000568572.1	FAM96B Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 96, member B
chr7_+_99006232 Show fit	31.67	ENST00000403633.2	BUD31 Ensembl NCBI GeneCards UniProt NextProt Show fit	BUD31 homolog (S. cerevisiae)
chr17_-_65362678 Show fit	31.58	ENST00000357146.4 ENST00000356126.3	PSMD12 Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr7_+_6617039 Show fit	31.13	ENST00000405731.3 ENST00000396713.2 ENST00000396707.2 ENST00000335965.6 ENST00000396709.1 ENST00000483589.1 ENST00000396706.2	ZDHHC4 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, DHHC-type containing 4
chr20_+_16710606 Show fit	30.86	ENST00000377943.5 ENST00000246071.6	SNRPB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptide B
chr8_-_38034192 Show fit	30.44	ENST00000520755.1	LSM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_+_40985407 Show fit	30.31	ENST00000586114.1 ENST00000590720.1 ENST00000585805.1 ENST00000541124.1 ENST00000441946.2 ENST00000591152.1 ENST00000589469.1 ENST00000293362.3 ENST00000592169.1	PSME3 Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr6_+_33257346 Show fit	30.20	ENST00000374606.5 ENST00000374610.2 ENST00000374607.1	PFDN6 Ensembl NCBI GeneCards UniProt NextProt Show fit	prefoldin subunit 6
chr1_-_246729544 Show fit	30.07	ENST00000544618.1 ENST00000366514.4	TFB2M Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor B2, mitochondrial
chr8_-_38034234 Show fit	29.87	ENST00000311351.4	LSM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr21_-_33984865 Show fit	29.84	ENST00000458138.1	C21orf59 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 21 open reading frame 59
chr9_-_35103105 Show fit	29.49	ENST00000452248.2 ENST00000356493.5	STOML2 Ensembl NCBI GeneCards UniProt NextProt Show fit	stomatin (EPB72)-like 2
chr11_+_73882311 Show fit	29.44	ENST00000398427.4 ENST00000544401.1	PPME1 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase methylesterase 1
chr11_-_65655906 Show fit	29.43	ENST00000533045.1 ENST00000338369.2 ENST00000357519.4	FIBP Ensembl NCBI GeneCards UniProt NextProt Show fit	fibroblast growth factor (acidic) intracellular binding protein
chr14_+_90722886 Show fit	29.26	ENST00000543772.2	PSMC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, ATPase, 1
chr7_+_99006550 Show fit	29.21	ENST00000222969.5	BUD31 Ensembl NCBI GeneCards UniProt NextProt Show fit	BUD31 homolog (S. cerevisiae)
chr21_-_33984888 Show fit	29.00	ENST00000382549.4 ENST00000540881.1	C21orf59 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 21 open reading frame 59
chr15_+_63340553 Show fit	28.89	ENST00000334895.5	TPM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tropomyosin 1 (alpha)
chr11_+_73882144 Show fit	28.88	ENST00000328257.8	PPME1 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase methylesterase 1
chr3_+_57541975 Show fit	28.74	ENST00000487257.1 ENST00000311180.8	PDE12 Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 12
chr10_+_89264625 Show fit	28.67	ENST00000371996.4 ENST00000371994.4	MINPP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	multiple inositol-polyphosphate phosphatase 1
chr11_-_95657231 Show fit	28.42	ENST00000409459.1 ENST00000352297.7 ENST00000393223.3 ENST00000346299.5	MTMR2 Ensembl NCBI GeneCards UniProt NextProt Show fit	myotubularin related protein 2
chr19_+_16296191 Show fit	28.31	ENST00000589852.1 ENST00000263384.7 ENST00000588367.1 ENST00000587351.1	FAM32A Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 32, member A
chr1_-_165738072 Show fit	28.02	ENST00000481278.1	TMCO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane and coiled-coil domains 1
chr3_-_131221790 Show fit	27.98	ENST00000512877.1 ENST00000264995.3 ENST00000511168.1 ENST00000425847.2	MRPL3 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L3
chr14_+_75348592 Show fit	27.94	ENST00000334220.4	DLST Ensembl NCBI GeneCards UniProt NextProt Show fit	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr14_+_90722839 Show fit	27.71	ENST00000261303.8 ENST00000553835.1	PSMC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, ATPase, 1
chr14_-_57735528 Show fit	27.50	ENST00000340918.7 ENST00000413566.2	EXOC5 Ensembl NCBI GeneCards UniProt NextProt Show fit	exocyst complex component 5
chr7_+_98923505 Show fit	27.49	ENST00000432884.2 ENST00000262942.5	ARPC1A Ensembl NCBI GeneCards UniProt NextProt Show fit	actin related protein 2/3 complex, subunit 1A, 41kDa
chr6_+_33239787 Show fit	27.47	ENST00000439602.2 ENST00000474973.1	RPS18 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S18
chr14_-_67826486 Show fit	27.39	ENST00000555431.1 ENST00000554236.1 ENST00000555474.1	ATP6V1D Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr19_-_55791563 Show fit	27.39	ENST00000588971.1 ENST00000255631.5 ENST00000587551.1	HSPBP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr1_-_20987851 Show fit	27.34	ENST00000464364.1 ENST00000602624.2	DDOST Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr17_+_73008755 Show fit	27.22	ENST00000584208.1 ENST00000301585.5	ICT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	immature colon carcinoma transcript 1
chr1_+_169337172 Show fit	27.18	ENST00000367807.3 ENST00000367808.3 ENST00000329281.2 ENST00000420531.1	BLZF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	basic leucine zipper nuclear factor 1
chr7_+_44240520 Show fit	26.99	ENST00000496112.1 ENST00000223369.2	YKT6 Ensembl NCBI GeneCards UniProt NextProt Show fit	YKT6 v-SNARE homolog (S. cerevisiae)
chr1_-_154946825 Show fit	26.94	ENST00000368453.4 ENST00000368450.1 ENST00000366442.2	SHC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	SHC (Src homology 2 domain containing) transforming protein 1
chr14_-_24701539 Show fit	26.94	ENST00000534348.1 ENST00000524927.1 ENST00000250495.5	NEDD8-MDP1 Ensembl NCBI GeneCards UniProt NextProt Show fit NEDD8 Ensembl NCBI GeneCards UniProt NextProt Show fit	NEDD8-MDP1 readthrough neural precursor cell expressed, developmentally down-regulated 8
chr16_+_23652773 Show fit	26.89	ENST00000563998.1 ENST00000568589.1 ENST00000568272.1	DCTN5 Ensembl NCBI GeneCards UniProt NextProt Show fit	dynactin 5 (p25)
chr10_+_75504105 Show fit	26.79	ENST00000535742.1 ENST00000546025.1 ENST00000345254.4 ENST00000540668.1 ENST00000339365.2 ENST00000411652.2	SEC24C Ensembl NCBI GeneCards UniProt NextProt Show fit	SEC24 family member C
chr1_-_43855479 Show fit	26.79	ENST00000290663.6 ENST00000372457.4	MED8 Ensembl NCBI GeneCards UniProt NextProt Show fit	mediator complex subunit 8
chr3_-_28390581 Show fit	26.78	ENST00000479665.1	AZI2 Ensembl NCBI GeneCards UniProt NextProt Show fit	5-azacytidine induced 2
chr11_-_64085533 Show fit	26.77	ENST00000544844.1	TRMT112 Ensembl NCBI GeneCards UniProt NextProt Show fit	tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr6_-_31620403 Show fit	26.58	ENST00000451898.1 ENST00000439687.2 ENST00000362049.6 ENST00000424480.1	BAG6 Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-associated athanogene 6
chr1_-_20987889 Show fit	26.57	ENST00000415136.2	DDOST Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr1_-_27216729 Show fit	26.52	ENST00000431781.2 ENST00000374135.4	GPN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	GPN-loop GTPase 2
chr1_-_165738085 Show fit	26.39	ENST00000464650.1 ENST00000392129.6	TMCO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane and coiled-coil domains 1
chr17_+_57784997 Show fit	26.23	ENST00000537567.1 ENST00000539763.1 ENST00000587945.1 ENST00000536180.1 ENST00000589823.2 ENST00000592106.1 ENST00000591315.1 ENST00000545362.1	VMP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuole membrane protein 1
chr7_-_99006443 Show fit	26.18	ENST00000350498.3	PDAP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	PDGFA associated protein 1
chr21_-_33985127 Show fit	26.15	ENST00000290155.3	C21orf59 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 21 open reading frame 59
chr19_+_19626531 Show fit	25.97	ENST00000507754.4	NDUFA13 Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr12_+_6833437 Show fit	25.85	ENST00000534947.1 ENST00000541866.1 ENST00000534877.1 ENST00000538753.1	COPS7A Ensembl NCBI GeneCards UniProt NextProt Show fit	COP9 signalosome subunit 7A
chr16_+_20817761 Show fit	25.80	ENST00000568046.1 ENST00000261377.6	AC004381.6 Ensembl NCBI GeneCards UniProt NextProt Show fit	Putative RNA exonuclease NEF-sp
chr17_+_33914460 Show fit	25.77	ENST00000537622.2	AP2B1 Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 2, beta 1 subunit
chr5_+_82373379 Show fit	25.65	ENST00000396027.4 ENST00000511817.1	XRCC4 Ensembl NCBI GeneCards UniProt NextProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 4
chr15_+_63340775 Show fit	25.56	ENST00000559281.1 ENST00000317516.7	TPM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tropomyosin 1 (alpha)
chr17_+_7155819 Show fit	25.53	ENST00000570322.1 ENST00000576496.1 ENST00000574841.2	ELP5 Ensembl NCBI GeneCards UniProt NextProt Show fit	elongator acetyltransferase complex subunit 5
chr3_+_100428188 Show fit	25.39	ENST00000418917.2 ENST00000490574.1	TFG Ensembl NCBI GeneCards UniProt NextProt Show fit	TRK-fused gene
chrX_+_69509927 Show fit	25.38	ENST00000374403.3	KIF4A Ensembl NCBI GeneCards UniProt NextProt Show fit	kinesin family member 4A
chr12_+_6833237 Show fit	25.26	ENST00000229251.3 ENST00000539735.1 ENST00000538410.1	COPS7A Ensembl NCBI GeneCards UniProt NextProt Show fit	COP9 signalosome subunit 7A
chr3_-_57583130 Show fit	25.22	ENST00000303436.6	ARF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor 4
chr10_+_51371390 Show fit	25.07	ENST00000478381.1 ENST00000451577.2 ENST00000374098.2 ENST00000374097.2	TIMM23B Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr7_+_100770328 Show fit	25.01	ENST00000223095.4 ENST00000445463.2	SERPINE1 Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr7_-_2281802 Show fit	24.91	ENST00000242257.8 ENST00000440306.2	FTSJ2 Ensembl NCBI GeneCards UniProt NextProt Show fit	FtsJ RNA methyltransferase homolog 2 (E. coli)
chr9_+_33264861 Show fit	24.91	ENST00000223500.8	CHMP5 Ensembl NCBI GeneCards UniProt NextProt Show fit	charged multivesicular body protein 5
chr1_-_17380630 Show fit	24.86	ENST00000375499.3	SDHB Ensembl NCBI GeneCards UniProt NextProt Show fit	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr5_+_82373317 Show fit	24.68	ENST00000282268.3 ENST00000338635.6	XRCC4 Ensembl NCBI GeneCards UniProt NextProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 4
chr22_+_19419425 Show fit	24.55	ENST00000333130.3	MRPL40 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L40
chr17_+_7155556 Show fit	24.44	ENST00000570500.1 ENST00000574993.1 ENST00000396628.2 ENST00000573657.1	ELP5 Ensembl NCBI GeneCards UniProt NextProt Show fit	elongator acetyltransferase complex subunit 5
chr12_-_44200146 Show fit	24.44	ENST00000395510.2 ENST00000325127.4	TWF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	twinfilin actin-binding protein 1
chr3_-_119396193 Show fit	24.42	ENST00000484810.1 ENST00000497116.1 ENST00000261070.2	COX17 Ensembl NCBI GeneCards UniProt NextProt Show fit	COX17 cytochrome c oxidase copper chaperone
chr11_-_18548426 Show fit	24.34	ENST00000357193.3 ENST00000536719.1	TSG101 Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor susceptibility 101
chrX_+_21958674 Show fit	24.12	ENST00000404933.2	SMS Ensembl NCBI GeneCards UniProt NextProt Show fit	spermine synthase
chr19_+_9938562 Show fit	24.08	ENST00000586895.1 ENST00000358666.3 ENST00000590068.1 ENST00000593087.1	UBL5 Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-like 5
chr1_-_20987982 Show fit	24.04	ENST00000375048.3	DDOST Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr12_+_120907622 Show fit	23.88	ENST00000392509.2 ENST00000549649.1 ENST00000548342.1	DYNLL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, light chain, LC8-type 1
chrX_+_21958814 Show fit	23.80	ENST00000379404.1 ENST00000415881.2	SMS Ensembl NCBI GeneCards UniProt NextProt Show fit	spermine synthase
chr3_-_57583052 Show fit	23.80	ENST00000496292.1 ENST00000489843.1	ARF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor 4
chr7_+_100860949 Show fit	23.78	ENST00000305105.2	ZNHIT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, HIT-type containing 1
chrX_+_11129388 Show fit	23.77	ENST00000321143.4 ENST00000380763.3 ENST00000380762.4	HCCS Ensembl NCBI GeneCards UniProt NextProt Show fit	holocytochrome c synthase
chr17_+_33914276 Show fit	23.76	ENST00000592545.1 ENST00000538556.1 ENST00000312678.8 ENST00000589344.1	AP2B1 Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 2, beta 1 subunit
chr19_-_59070239 Show fit	23.60	ENST00000595957.1 ENST00000253023.3	UBE2M Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2M
chr20_+_19867150 Show fit	23.47	ENST00000255006.6	RIN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras and Rab interactor 2
chr14_+_77924204 Show fit	23.40	ENST00000555133.1	AHSA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr3_+_130613226 Show fit	23.34	ENST00000509662.1 ENST00000328560.8 ENST00000428331.2 ENST00000359644.3 ENST00000422190.2	ATP2C1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Ca++ transporting, type 2C, member 1
chrX_-_40594755 Show fit	23.25	ENST00000324817.1	MED14 Ensembl NCBI GeneCards UniProt NextProt Show fit	mediator complex subunit 14
chr16_+_56485402 Show fit	23.17	ENST00000566157.1 ENST00000562150.1 ENST00000561646.1 ENST00000568397.1	OGFOD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr4_-_120988229 Show fit	23.09	ENST00000296509.6	MAD2L1 Ensembl NCBI GeneCards UniProt NextProt Show fit	MAD2 mitotic arrest deficient-like 1 (yeast)
chr17_+_7155343 Show fit	23.05	ENST00000573513.1 ENST00000354429.2 ENST00000574255.1 ENST00000396627.2 ENST00000356683.2	ELP5 Ensembl NCBI GeneCards UniProt NextProt Show fit	elongator acetyltransferase complex subunit 5
chr10_-_51623203 Show fit	22.96	ENST00000444743.1 ENST00000374065.3 ENST00000374064.3 ENST00000260867.4	TIMM23 Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of inner mitochondrial membrane 23 homolog (yeast)
chr3_+_100428316 Show fit	22.85	ENST00000479672.1 ENST00000476228.1 ENST00000463568.1	TFG Ensembl NCBI GeneCards UniProt NextProt Show fit	TRK-fused gene
chr3_+_100428268 Show fit	22.84	ENST00000240851.4	TFG Ensembl NCBI GeneCards UniProt NextProt Show fit	TRK-fused gene
chr20_-_2451395 Show fit	22.77	ENST00000339610.6 ENST00000381342.2 ENST00000438552.2	SNRPB Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptides B and B1
chr5_+_125758813 Show fit	22.62	ENST00000285689.3 ENST00000515200.1	GRAMD3 Ensembl NCBI GeneCards UniProt NextProt Show fit	GRAM domain containing 3
chr5_+_102455968 Show fit	22.41	ENST00000358359.3	PPIP5K2 Ensembl NCBI GeneCards UniProt NextProt Show fit	diphosphoinositol pentakisphosphate kinase 2
chr6_+_142622991 Show fit	22.41	ENST00000230173.6 ENST00000367608.2	GPR126 Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 126
chr19_-_2427536 Show fit	22.35	ENST00000591871.1	TIMM13 Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr1_-_113247543 Show fit	22.32	ENST00000414971.1 ENST00000534717.1	RHOC Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member C
chr6_-_31620455 Show fit	22.30	ENST00000437771.1 ENST00000404765.2 ENST00000375964.6 ENST00000211379.5	BAG6 Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-associated athanogene 6
chr9_+_33265011 Show fit	22.25	ENST00000419016.2	CHMP5 Ensembl NCBI GeneCards UniProt NextProt Show fit	charged multivesicular body protein 5
chr9_-_127177703 Show fit	22.22	ENST00000259457.3 ENST00000536392.1 ENST00000441097.1	PSMB7 Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 7
chr11_+_9406169 Show fit	22.17	ENST00000379719.3 ENST00000527431.1	IPO7 Ensembl NCBI GeneCards UniProt NextProt Show fit	importin 7
chr19_-_55791540 Show fit	22.12	ENST00000433386.2	HSPBP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr5_+_125758865 Show fit	21.96	ENST00000542322.1 ENST00000544396.1	GRAMD3 Ensembl NCBI GeneCards UniProt NextProt Show fit	GRAM domain containing 3
chrX_+_100075368 Show fit	21.93	ENST00000415585.2 ENST00000372972.2 ENST00000413437.1	CSTF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr3_+_130613001 Show fit	21.82	ENST00000504948.1 ENST00000513801.1 ENST00000505072.1	ATP2C1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Ca++ transporting, type 2C, member 1
chr2_+_99225018 Show fit	21.80	ENST00000357765.2 ENST00000409975.1	UNC50 Ensembl NCBI GeneCards UniProt NextProt Show fit	unc-50 homolog (C. elegans)
chr22_+_39898325 Show fit	21.66	ENST00000325301.2 ENST00000404569.1	MIEF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial elongation factor 1
chr16_+_20818020 Show fit	21.63	ENST00000564274.1 ENST00000563068.1	AC004381.6 Ensembl NCBI GeneCards UniProt NextProt Show fit	Putative RNA exonuclease NEF-sp
chr9_+_133454943 Show fit	21.63	ENST00000319725.9	FUBP3 Ensembl NCBI GeneCards UniProt NextProt Show fit	far upstream element (FUSE) binding protein 3
chr11_-_64084959 Show fit	21.57	ENST00000535750.1 ENST00000535126.1 ENST00000539854.1 ENST00000308774.2	TRMT112 Ensembl NCBI GeneCards UniProt NextProt Show fit	tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr1_+_174969262 Show fit	21.50	ENST00000406752.1 ENST00000405362.1	CACYBP Ensembl NCBI GeneCards UniProt NextProt Show fit	calcyclin binding protein
chr8_-_77912431 Show fit	21.48	ENST00000357039.4 ENST00000522527.1	PEX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxisomal biogenesis factor 2
chr3_+_130612803 Show fit	21.41	ENST00000510168.1 ENST00000508532.1	ATP2C1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Ca++ transporting, type 2C, member 1
chr12_-_49351228 Show fit	21.34	ENST00000541959.1 ENST00000447318.2	ARF3 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor 3
chr6_-_42981651 Show fit	21.31	ENST00000244711.3	MEA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	male-enhanced antigen 1
chr5_+_140071011 Show fit	21.28	ENST00000230771.3 ENST00000509299.1 ENST00000503873.1 ENST00000435019.2 ENST00000437649.2 ENST00000432671.2	HARS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	histidyl-tRNA synthetase 2, mitochondrial
chr3_-_64009102 Show fit	21.13	ENST00000478185.1 ENST00000482510.1 ENST00000497323.1 ENST00000492933.1 ENST00000295901.4	PSMD6 Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr2_-_207024233 Show fit	21.08	ENST00000423725.1 ENST00000233190.6	NDUFS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV1_ERF_FEV_ELF1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
41.6	124.7	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
25.5	76.6	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
20.9	167.0	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
19.3	58.0	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
19.3	57.9	GO:0048611	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
17.6	52.7	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
16.0	47.9	GO:0006597	spermine biosynthetic process(GO:0006597)
15.5	77.6	GO:0019348	dolichol metabolic process(GO:0019348)
15.2	45.7	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
14.2	56.8	GO:1904327	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
13.6	54.3	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
12.3	36.8	GO:0006624	vacuolar protein processing(GO:0006624)
12.2	109.5	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
12.2	24.3	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878)
12.2	48.6	GO:0032218	riboflavin transport(GO:0032218)
12.1	48.3	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
11.5	11.5	GO:0000729	DNA double-strand break processing(GO:0000729)
11.1	66.6	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
10.5	42.0	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
10.0	29.9	GO:0001300	chronological cell aging(GO:0001300)
9.9	29.8	GO:0002184	cytoplasmic translational termination(GO:0002184)
9.9	49.5	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
9.8	39.2	GO:0021539	subthalamus development(GO:0021539)
9.8	29.4	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
9.3	27.9	GO:0019474	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
9.1	63.9	GO:0007144	female meiosis I(GO:0007144)
9.0	36.1	GO:0006203	dGTP catabolic process(GO:0006203)
8.9	44.6	GO:1904578	response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
8.8	26.5	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
8.8	43.9	GO:0002084	protein depalmitoylation(GO:0002084)
8.6	25.7	GO:0018283	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
8.5	25.5	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
8.3	25.0	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
8.3	91.5	GO:0045176	apical protein localization(GO:0045176)
8.2	32.9	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
8.1	40.6	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
8.0	95.9	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
7.8	38.9	GO:1904274	tricellular tight junction assembly(GO:1904274)
7.8	31.1	GO:0090296	regulation of mitochondrial DNA replication(GO:0090296)
7.7	30.7	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
7.6	30.4	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
7.5	22.5	GO:0042350	GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
7.4	37.0	GO:0046203	spermidine catabolic process(GO:0046203)
7.3	29.1	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
7.3	50.9	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
7.1	57.0	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
7.1	28.4	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
6.8	20.3	GO:0010796	regulation of multivesicular body size(GO:0010796)
6.5	19.4	GO:0097359	UDP-glucosylation(GO:0097359)
6.4	19.2	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
6.4	159.6	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
6.2	24.8	GO:2000232	regulation of rRNA processing(GO:2000232)
6.2	18.5	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
6.1	30.5	GO:0030047	actin modification(GO:0030047)
6.0	35.9	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
6.0	17.9	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
5.9	17.8	GO:0030327	prenylated protein catabolic process(GO:0030327)
5.9	29.5	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
5.6	16.8	GO:0046680	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
5.5	16.6	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
5.5	22.1	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
5.5	11.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
5.5	43.7	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
5.4	21.7	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
5.4	16.1	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
5.3	15.9	GO:0090034	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
5.2	250.9	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
5.2	114.0	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
5.2	15.5	GO:0097498	endothelial tube lumen extension(GO:0097498)
5.1	82.4	GO:0043248	proteasome assembly(GO:0043248)
5.0	55.3	GO:2000210	positive regulation of anoikis(GO:2000210)
5.0	70.0	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
5.0	119.9	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
5.0	15.0	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
5.0	24.8	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
4.9	24.5	GO:0019323	pentose catabolic process(GO:0019323)
4.9	68.2	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
4.8	52.9	GO:0006983	ER overload response(GO:0006983)
4.8	14.3	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
4.7	137.4	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
4.6	13.7	GO:0072313	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
4.5	85.3	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
4.5	67.1	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
4.4	71.1	GO:0000338	protein deneddylation(GO:0000338)
4.4	53.2	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
4.4	13.2	GO:0060166	olfactory pit development(GO:0060166)
4.4	144.7	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
4.4	48.2	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
4.2	4.2	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
4.2	46.7	GO:2000576	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
4.2	16.9	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
4.1	66.3	GO:0045116	protein neddylation(GO:0045116)
4.1	12.4	GO:0033341	regulation of collagen binding(GO:0033341)
4.1	32.7	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
4.1	300.3	GO:0070125	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
4.0	72.0	GO:0075713	establishment of integrated proviral latency(GO:0075713)
3.9	23.7	GO:0070475	rRNA base methylation(GO:0070475)
3.9	7.9	GO:0046070	dGTP metabolic process(GO:0046070)
3.9	15.7	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
3.9	31.0	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
3.8	30.7	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
3.8	11.3	GO:1902309	regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
3.8	30.0	GO:0016559	peroxisome fission(GO:0016559)
3.7	7.4	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
3.6	21.5	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
3.6	10.7	GO:0051031	tRNA transport(GO:0051031)
3.6	35.6	GO:1904869	regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
3.5	24.5	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
3.5	59.4	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
3.4	3.4	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
3.4	10.2	GO:0015680	intracellular copper ion transport(GO:0015680)
3.4	20.4	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
3.4	27.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
3.4	13.4	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
3.3	23.4	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
3.3	13.3	GO:0001188	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
3.3	13.2	GO:0017198	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
3.2	9.7	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
3.1	15.5	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
3.1	6.2	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
3.1	21.5	GO:1904872	regulation of telomerase RNA localization to Cajal body(GO:1904872)
3.0	6.1	GO:0051036	regulation of endosome size(GO:0051036)
2.9	20.5	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
2.9	41.0	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
2.9	8.7	GO:0032765	lymphotoxin A production(GO:0032641) positive regulation of mast cell cytokine production(GO:0032765) lymphotoxin A biosynthetic process(GO:0042109)
2.9	17.4	GO:0001692	histamine metabolic process(GO:0001692)
2.9	17.4	GO:0006348	chromatin silencing at telomere(GO:0006348)
2.9	23.1	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
2.9	11.5	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
2.9	31.6	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
2.9	14.3	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
2.9	8.6	GO:0002188	translation reinitiation(GO:0002188)
2.8	71.1	GO:0006829	zinc II ion transport(GO:0006829)
2.8	28.3	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
2.8	14.1	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
2.8	14.1	GO:0015677	copper ion import(GO:0015677)
2.8	19.7	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
2.8	14.0	GO:0000012	single strand break repair(GO:0000012)
2.8	13.8	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
2.8	13.8	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
2.8	8.3	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
2.7	38.0	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.7	37.5	GO:0006293	nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
2.7	45.4	GO:0034063	stress granule assembly(GO:0034063)
2.7	5.3	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
2.7	29.2	GO:0022417	protein maturation by protein folding(GO:0022417)
2.6	18.4	GO:0007096	regulation of exit from mitosis(GO:0007096)
2.6	7.8	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
2.6	54.3	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
2.6	12.8	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
2.6	17.9	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
2.5	7.6	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
2.5	231.7	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
2.5	5.0	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
2.5	20.0	GO:0010032	meiotic chromosome condensation(GO:0010032)
2.5	15.0	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
2.5	10.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
2.5	32.4	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
2.5	24.7	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
2.4	12.2	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
2.4	19.3	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
2.4	31.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
2.4	14.5	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
2.4	9.6	GO:0007008	outer mitochondrial membrane organization(GO:0007008)
2.4	23.9	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
2.4	45.4	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
2.4	9.4	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
2.3	43.8	GO:0007220	Notch receptor processing(GO:0007220)
2.3	39.1	GO:0006020	inositol metabolic process(GO:0006020)
2.3	16.0	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
2.3	175.6	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
2.3	15.9	GO:0070294	renal sodium ion absorption(GO:0070294)
2.3	15.9	GO:0070535	negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
2.3	83.8	GO:0042407	cristae formation(GO:0042407)
2.3	4.5	GO:0044111	development involved in symbiotic interaction(GO:0044111)
2.3	65.5	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
2.2	8.9	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
2.2	19.7	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
2.2	6.6	GO:0032762	mast cell cytokine production(GO:0032762) dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
2.2	6.6	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
2.2	17.4	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
2.2	10.8	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
2.1	21.2	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
2.1	6.2	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
2.1	24.9	GO:0006105	succinate metabolic process(GO:0006105)
2.1	4.1	GO:0051462	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
2.1	57.6	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
2.1	37.0	GO:0035641	locomotory exploration behavior(GO:0035641)
2.0	8.2	GO:1904688	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
2.0	16.1	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
2.0	4.0	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
2.0	8.0	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
2.0	14.0	GO:1903895	negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
2.0	6.0	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
2.0	9.9	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
2.0	17.8	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
2.0	23.6	GO:0006108	malate metabolic process(GO:0006108)
2.0	17.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
1.9	3.9	GO:0019087	transformation of host cell by virus(GO:0019087)
1.9	19.1	GO:0051665	membrane raft localization(GO:0051665)
1.9	7.6	GO:0070141	response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492)
1.9	11.4	GO:0016191	synaptic vesicle uncoating(GO:0016191)
1.9	9.4	GO:0051414	response to cortisol(GO:0051414)
1.9	7.5	GO:0060849	radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
1.9	3.7	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
1.8	14.8	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.8	20.3	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
1.8	9.2	GO:0034201	response to oleic acid(GO:0034201)
1.8	32.6	GO:0070584	mitochondrion morphogenesis(GO:0070584)
1.8	5.4	GO:0010286	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
1.8	25.1	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
1.8	85.8	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
1.8	112.6	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.8	5.3	GO:0002752	leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
1.8	7.1	GO:0032053	ciliary basal body organization(GO:0032053)
1.8	10.6	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
1.8	24.7	GO:0008053	mitochondrial fusion(GO:0008053)
1.7	227.1	GO:0006626	protein targeting to mitochondrion(GO:0006626)
1.7	7.0	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
1.7	15.6	GO:0031167	rRNA methylation(GO:0031167)
1.7	13.8	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
1.7	119.6	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
1.7	10.2	GO:0033504	floor plate development(GO:0033504)
1.7	3.4	GO:0000393	spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
1.7	8.4	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
1.7	38.3	GO:0045948	positive regulation of translational initiation(GO:0045948)
1.7	5.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
1.7	6.6	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
1.7	29.9	GO:0001682	tRNA 5'-leader removal(GO:0001682)
1.7	3.3	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
1.6	45.7	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
1.6	8.1	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.6	6.5	GO:1990481	mRNA pseudouridine synthesis(GO:1990481)
1.6	8.0	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.6	4.8	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
1.6	33.3	GO:0034389	lipid particle organization(GO:0034389)
1.6	57.0	GO:0007029	endoplasmic reticulum organization(GO:0007029)
1.6	36.2	GO:0006144	purine nucleobase metabolic process(GO:0006144)
1.5	6.2	GO:0060363	cranial suture morphogenesis(GO:0060363)
1.5	4.6	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
1.5	109.6	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.5	6.1	GO:0070897	DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
1.5	12.1	GO:1902969	mitotic DNA replication(GO:1902969)
1.5	16.5	GO:0070200	establishment of protein localization to telomere(GO:0070200)
1.5	6.0	GO:0097480	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
1.5	3.0	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
1.5	26.9	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
1.5	4.4	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
1.4	28.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
1.4	8.4	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
1.4	44.9	GO:0090383	phagosome acidification(GO:0090383)
1.4	5.5	GO:2000197	regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
1.4	18.0	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
1.4	19.2	GO:0038003	opioid receptor signaling pathway(GO:0038003)
1.4	4.1	GO:0034227	tRNA thio-modification(GO:0034227)
1.4	4.1	GO:0072683	T cell extravasation(GO:0072683)
1.3	10.7	GO:0042775	ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775)
1.3	6.7	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
1.3	40.1	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
1.3	5.3	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.3	97.3	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
1.3	22.3	GO:0006415	translational termination(GO:0006415)
1.3	31.1	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
1.3	2.6	GO:0060295	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
1.3	7.7	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
1.3	7.7	GO:1901977	negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
1.3	6.4	GO:0070836	caveola assembly(GO:0070836)
1.3	3.8	GO:1901873	regulation of post-translational protein modification(GO:1901873)
1.3	3.8	GO:0002183	cytoplasmic translational initiation(GO:0002183)
1.3	7.6	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.3	6.3	GO:0021553	olfactory nerve development(GO:0021553)
1.3	10.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
1.2	8.7	GO:0006102	isocitrate metabolic process(GO:0006102)
1.2	5.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
1.2	1.2	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
1.2	9.9	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
1.2	10.9	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.2	10.9	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.2	2.4	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
1.2	56.0	GO:1990090	cellular response to nerve growth factor stimulus(GO:1990090)
1.2	3.5	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
1.2	14.1	GO:0060546	negative regulation of necroptotic process(GO:0060546)
1.2	38.6	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
1.2	33.9	GO:0006903	vesicle targeting(GO:0006903)
1.2	4.7	GO:0033590	response to cobalamin(GO:0033590)
1.2	9.3	GO:0060717	chorion development(GO:0060717) negative regulation of inclusion body assembly(GO:0090084)
1.2	3.5	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
1.2	1.2	GO:0010726	positive regulation of hydrogen peroxide metabolic process(GO:0010726)
1.2	13.9	GO:0018206	peptidyl-methionine modification(GO:0018206)
1.1	1.1	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
1.1	6.9	GO:0048630	skeletal muscle tissue growth(GO:0048630)
1.1	84.3	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
1.1	5.7	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
1.1	5.7	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
1.1	5.7	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
1.1	9.0	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
1.1	11.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
1.1	15.6	GO:0000910	cytokinesis(GO:0000910)
1.1	4.4	GO:0060325	face morphogenesis(GO:0060325)
1.1	3.3	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.1	2.2	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
1.1	3.3	GO:1901355	response to rapamycin(GO:1901355)
1.1	12.0	GO:0006662	glycerol ether metabolic process(GO:0006662)
1.1	5.5	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
1.1	24.0	GO:0032607	interferon-alpha production(GO:0032607)
1.1	5.4	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
1.1	40.6	GO:0043486	histone exchange(GO:0043486)
1.1	4.3	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
1.1	17.0	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.0	26.1	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
1.0	3.1	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
1.0	9.4	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
1.0	3.1	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
1.0	32.1	GO:0032781	positive regulation of ATPase activity(GO:0032781)
1.0	14.4	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
1.0	7.1	GO:0048368	lateral mesoderm development(GO:0048368)
1.0	37.3	GO:0014003	oligodendrocyte development(GO:0014003)
1.0	3.0	GO:0034982	mitochondrial protein processing(GO:0034982)
1.0	3.0	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
1.0	8.0	GO:0035269	protein O-linked mannosylation(GO:0035269)
1.0	4.0	GO:0061743	motor learning(GO:0061743)
1.0	7.9	GO:0002934	desmosome organization(GO:0002934)
1.0	4.9	GO:0000963	mitochondrial RNA processing(GO:0000963)
1.0	3.9	GO:0043126	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
1.0	4.8	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
1.0	6.7	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
1.0	1.9	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.9	3.8	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.9	28.1	GO:0031648	protein destabilization(GO:0031648)
0.9	7.5	GO:0032836	glomerular basement membrane development(GO:0032836)
0.9	0.9	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.9	1.9	GO:0072093	ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.9	2.7	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.9	2.7	GO:0009597	detection of virus(GO:0009597)
0.9	3.6	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.9	2.7	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.9	1.8	GO:0036010	protein localization to endosome(GO:0036010)
0.9	6.2	GO:0036438	maintenance of lens transparency(GO:0036438)
0.9	4.4	GO:0032730	positive regulation of interleukin-1 alpha production(GO:0032730)
0.9	14.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.9	6.1	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.9	4.3	GO:0015865	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.8	3.4	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.8	5.0	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.8	9.0	GO:0017004	cytochrome complex assembly(GO:0017004)
0.8	35.0	GO:0035904	aorta development(GO:0035904)
0.8	3.9	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.8	2.3	GO:0000154	rRNA modification(GO:0000154)
0.8	1.5	GO:0015747	urate transport(GO:0015747)
0.8	2.3	GO:0006566	threonine metabolic process(GO:0006566)
0.8	2.3	GO:0046294	formaldehyde catabolic process(GO:0046294)
0.7	3.7	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.7	2.2	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
0.7	11.1	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.7	50.9	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.7	27.0	GO:0042733	embryonic digit morphogenesis(GO:0042733)
0.7	25.5	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.7	23.3	GO:2000810	regulation of bicellular tight junction assembly(GO:2000810)
0.7	22.5	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.7	14.5	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.7	3.6	GO:0032508	DNA duplex unwinding(GO:0032508)
0.7	1.4	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.7	7.1	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.7	3.5	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.7	2.1	GO:2000864	estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.7	6.9	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.7	8.2	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.7	14.2	GO:0030539	male genitalia development(GO:0030539)
0.7	14.1	GO:0006622	protein targeting to lysosome(GO:0006622)
0.7	16.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.7	2.7	GO:0019249	lactate biosynthetic process(GO:0019249)
0.7	6.6	GO:0010815	bradykinin catabolic process(GO:0010815)
0.7	7.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.7	10.5	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.7	5.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.7	4.6	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.6	0.6	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.6	1.9	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.6	1.3	GO:0051182	coenzyme transport(GO:0051182)
0.6	3.2	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.6	8.3	GO:0045008	depyrimidination(GO:0045008)
0.6	4.4	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.6	2.5	GO:0048254	snoRNA localization(GO:0048254)
0.6	6.7	GO:0061339	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.6	2.4	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.6	6.6	GO:0046415	urate metabolic process(GO:0046415)
0.6	3.0	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.6	2.9	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.6	5.7	GO:0035878	nail development(GO:0035878)
0.6	2.3	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.6	1.7	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.6	16.5	GO:0006270	DNA replication initiation(GO:0006270)
0.6	1.7	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.6	1.7	GO:0003266	regulation of secondary heart field cardioblast proliferation(GO:0003266) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.6	10.2	GO:0022900	electron transport chain(GO:0022900)
0.6	0.6	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.6	16.7	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.6	5.0	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.5	3.3	GO:0038161	prolactin signaling pathway(GO:0038161)
0.5	15.3	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.5	4.9	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.5	1.6	GO:0090435	protein localization to nuclear pore(GO:0090204) protein localization to nuclear envelope(GO:0090435)
0.5	24.8	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.5	8.4	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.5	3.1	GO:0046618	drug export(GO:0046618)
0.5	4.1	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.5	0.5	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.5	17.0	GO:1901985	positive regulation of protein acetylation(GO:1901985)
0.5	1.5	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.5	1.5	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.5	2.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.5	2.9	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.5	2.0	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.5	16.0	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.5	16.4	GO:0006693	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.5	7.2	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.5	2.4	GO:0007172	signal complex assembly(GO:0007172)
0.5	4.3	GO:0015727	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.5	6.1	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.5	5.6	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.5	4.6	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.5	1.8	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.5	6.0	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.5	5.0	GO:0051290	protein heterotetramerization(GO:0051290)
0.5	1.4	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
0.5	3.6	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.5	5.9	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.4	6.7	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.4	10.4	GO:0046039	GTP metabolic process(GO:0046039)
0.4	2.2	GO:1905216	positive regulation of RNA binding(GO:1905216)
0.4	15.1	GO:0090307	mitotic spindle assembly(GO:0090307)
0.4	10.7	GO:0009206	ATP biosynthetic process(GO:0006754) ribonucleoside triphosphate biosynthetic process(GO:0009201) purine ribonucleoside triphosphate biosynthetic process(GO:0009206)
0.4	10.7	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.4	65.2	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.4	0.4	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.4	1.7	GO:0010585	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.4	3.7	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.4	7.4	GO:0006012	galactose metabolic process(GO:0006012)
0.4	0.8	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.4	3.7	GO:0048853	forebrain morphogenesis(GO:0048853)
0.4	2.0	GO:0098502	DNA dephosphorylation(GO:0098502)
0.4	48.1	GO:0000209	protein polyubiquitination(GO:0000209)
0.4	11.6	GO:0008214	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.4	0.8	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.4	3.2	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.4	27.4	GO:0006110	regulation of glycolytic process(GO:0006110)
0.4	7.8	GO:0072413	signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.4	5.0	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.4	3.8	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.4	12.8	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.4	3.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.4	2.2	GO:0018344	protein geranylgeranylation(GO:0018344)
0.4	1.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.4	22.0	GO:0008033	tRNA processing(GO:0008033)
0.4	8.3	GO:0050873	brown fat cell differentiation(GO:0050873)
0.4	14.8	GO:0051028	mRNA transport(GO:0051028)
0.4	0.7	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.4	2.1	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.4	1.4	GO:0065002	intracellular protein transmembrane transport(GO:0065002)
0.4	2.5	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3	4.2	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.3	2.4	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.3	1.7	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.3	5.2	GO:0046069	cGMP catabolic process(GO:0046069)
0.3	54.6	GO:0006457	protein folding(GO:0006457)
0.3	4.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.3	3.8	GO:0031033	myosin filament organization(GO:0031033) positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.3	9.2	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.3	2.0	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.3	1.4	GO:0019046	release from viral latency(GO:0019046)
0.3	3.7	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3	1.7	GO:0032790	ribosome disassembly(GO:0032790)
0.3	4.3	GO:0006450	regulation of translational fidelity(GO:0006450)
0.3	6.3	GO:0006465	signal peptide processing(GO:0006465)
0.3	6.6	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.3	2.6	GO:0035897	proteolysis in other organism(GO:0035897)
0.3	13.7	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.3	88.3	GO:0043687	post-translational protein modification(GO:0043687)
0.3	46.1	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3	23.4	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.3	1.5	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.3	3.0	GO:0021942	layer formation in cerebral cortex(GO:0021819) radial glia guided migration of Purkinje cell(GO:0021942)
0.3	2.1	GO:0009249	protein lipoylation(GO:0009249)
0.3	4.8	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.3	1.8	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.3	0.6	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3	5.9	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.3	0.8	GO:0071918	urea transmembrane transport(GO:0071918)
0.3	1.7	GO:0010269	response to selenium ion(GO:0010269)
0.3	4.2	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.3	0.8	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.3	3.0	GO:0032446	protein modification by small protein conjugation(GO:0032446)
0.3	3.3	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.3	2.4	GO:0030308	negative regulation of cell growth(GO:0030308)
0.3	0.3	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.3	1.3	GO:0009957	epidermal cell fate specification(GO:0009957)
0.3	13.9	GO:0055007	cardiac muscle cell differentiation(GO:0055007)
0.3	3.9	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.3	1.0	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.3	1.5	GO:0051013	microtubule severing(GO:0051013)
0.3	5.8	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.3	2.0	GO:0006531	aspartate metabolic process(GO:0006531)
0.2	0.7	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.2	1.2	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.2	8.4	GO:0019731	antibacterial humoral response(GO:0019731)
0.2	1.4	GO:0000281	mitotic cytokinesis(GO:0000281)
0.2	0.2	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2	1.9	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.2	7.1	GO:0031398	positive regulation of protein ubiquitination(GO:0031398)
0.2	1.6	GO:0021511	spinal cord patterning(GO:0021511)
0.2	7.6	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.2	6.2	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.2	1.8	GO:0033623	regulation of integrin activation(GO:0033623)
0.2	5.4	GO:0097484	dendrite extension(GO:0097484)
0.2	0.7	GO:0016082	synaptic vesicle priming(GO:0016082)
0.2	3.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.2	1.9	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.2	5.1	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.2	1.3	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.2	0.6	GO:0006550	isoleucine metabolic process(GO:0006549) isoleucine catabolic process(GO:0006550)
0.2	1.0	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.2	1.4	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.2	0.8	GO:0044857	plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.2	8.2	GO:0016266	O-glycan processing(GO:0016266)
0.2	2.0	GO:0050821	protein stabilization(GO:0050821)
0.2	2.4	GO:0098927	vesicle-mediated transport between endosomal compartments(GO:0098927)
0.2	5.8	GO:0045333	cellular respiration(GO:0045333)
0.2	0.4	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.2	0.6	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.2	1.5	GO:0051291	protein heterooligomerization(GO:0051291)
0.2	5.6	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.2	7.3	GO:1901222	regulation of NIK/NF-kappaB signaling(GO:1901222)
0.2	4.7	GO:0008542	visual learning(GO:0008542)
0.2	5.2	GO:0033500	carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.2	48.9	GO:0006936	muscle contraction(GO:0006936)
0.2	1.1	GO:0010927	cellular component assembly involved in morphogenesis(GO:0010927)
0.2	0.3	GO:0021764	amygdala development(GO:0021764)
0.2	0.3	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.2	0.8	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2	6.3	GO:0032465	regulation of cytokinesis(GO:0032465)
0.2	0.5	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.2	0.5	GO:0043163	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.2	0.5	GO:0016259	selenocysteine metabolic process(GO:0016259) selenocysteine biosynthetic process(GO:0016260)
0.2	0.6	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
0.1	1.0	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.1	5.3	GO:0034249	negative regulation of cellular amide metabolic process(GO:0034249)
0.1	4.2	GO:0045739	positive regulation of DNA repair(GO:0045739)
0.1	1.0	GO:0070307	lens fiber cell development(GO:0070307)
0.1	0.4	GO:0034587	piRNA metabolic process(GO:0034587)
0.1	0.1	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.3	GO:0001675	acrosome assembly(GO:0001675)
0.1	1.3	GO:0051683	establishment of Golgi localization(GO:0051683)
0.1	5.7	GO:0070527	platelet aggregation(GO:0070527)
0.1	1.4	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	1.8	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	1.3	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.1	0.3	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
0.1	0.4	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.1	0.6	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.1	2.7	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.1	0.7	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1	1.0	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	1.7	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	2.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1	2.9	GO:0006826	iron ion transport(GO:0006826)
0.1	2.2	GO:0001558	regulation of cell growth(GO:0001558)
0.1	1.8	GO:0007638	mechanosensory behavior(GO:0007638)
0.1	2.3	GO:0042572	retinol metabolic process(GO:0042572)
0.1	1.0	GO:1903206	negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1	2.3	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.1	0.5	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.5	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.1	10.3	GO:0030449	regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.1	0.3	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.1	1.6	GO:0006783	heme biosynthetic process(GO:0006783)
0.1	0.6	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.1	6.3	GO:0043473	pigmentation(GO:0043473)
0.1	1.3	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.1	0.2	GO:0048548	regulation of pinocytosis(GO:0048548)
0.1	0.6	GO:0042711	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1	0.1	GO:0061511	centriole elongation(GO:0061511)
0.1	2.9	GO:0030516	regulation of axon extension(GO:0030516)
0.1	0.8	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.1	0.5	GO:0002863	positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.1	0.5	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	0.7	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1	2.8	GO:0001935	endothelial cell proliferation(GO:0001935)
0.1	0.5	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.1	5.2	GO:0046546	male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.1	0.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.2	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.1	1.2	GO:0019228	neuronal action potential(GO:0019228)
0.1	0.3	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	0.8	GO:0015813	L-glutamate transport(GO:0015813)
0.1	5.3	GO:0032990	cell part morphogenesis(GO:0032990) cell projection morphogenesis(GO:0048858)
0.1	0.3	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.1	0.3	GO:0042749	regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0	0.2	GO:0051934	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.2	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.9	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.0	1.9	GO:0031497	chromatin assembly(GO:0031497)
0.0	0.3	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.6	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	2.1	GO:0006970	response to osmotic stress(GO:0006970)
0.0	0.4	GO:0055022	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of heart growth(GO:0061117)
0.0	0.5	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.8	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.2	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.7	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	10.1	GO:0007283	spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0	0.4	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.7	GO:0045776	negative regulation of blood pressure(GO:0045776)
0.0	0.5	GO:1903391	regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109) regulation of adherens junction organization(GO:1903391)
0.0	0.1	GO:0070781	response to biotin(GO:0070781)
0.0	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.6	GO:1901655	cellular response to ketone(GO:1901655)
0.0	0.4	GO:0016445	somatic diversification of immunoglobulins(GO:0016445)
0.0	0.4	GO:0007595	lactation(GO:0007595)
0.0	1.5	GO:0070268	cornification(GO:0070268)
0.0	0.1	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	0.4	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	1.1	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0030316	osteoclast differentiation(GO:0030316)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.5	GO:0051168	nuclear export(GO:0051168)
0.0	0.2	GO:0046710	GDP metabolic process(GO:0046710)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
32.5	130.2	GO:0070985	TFIIK complex(GO:0070985)
27.5	82.4	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
16.0	191.9	GO:0031595	nuclear proteasome complex(GO:0031595)
14.8	59.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
14.7	88.4	GO:0071817	MMXD complex(GO:0071817)
12.5	225.9	GO:0034709	methylosome(GO:0034709)
12.5	49.9	GO:1990745	EARP complex(GO:1990745)
12.0	84.3	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
10.8	32.4	GO:0031372	UBC13-MMS2 complex(GO:0031372)
10.0	169.2	GO:0032059	bleb(GO:0032059)
9.9	29.8	GO:0018444	translation release factor complex(GO:0018444)
9.4	75.4	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
9.3	65.0	GO:0016272	prefoldin complex(GO:0016272)
9.0	27.0	GO:0097441	basilar dendrite(GO:0097441)
8.5	25.5	GO:0005656	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
8.5	8.5	GO:0097651	phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
8.5	67.7	GO:0032133	chromosome passenger complex(GO:0032133)
8.4	75.8	GO:0033588	Elongator holoenzyme complex(GO:0033588)
8.3	49.9	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
8.0	40.1	GO:0032021	NELF complex(GO:0032021)
8.0	40.1	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
8.0	40.0	GO:0000408	EKC/KEOPS complex(GO:0000408)
7.9	31.8	GO:0031510	SUMO activating enzyme complex(GO:0031510)
7.5	30.2	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
7.5	89.6	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
7.4	81.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
7.1	35.5	GO:1990425	ryanodine receptor complex(GO:1990425)
7.0	77.5	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
6.8	33.9	GO:0097149	centralspindlin complex(GO:0097149)
6.6	39.9	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
6.6	19.7	GO:0030689	Noc complex(GO:0030689)
6.5	38.9	GO:0061689	tricellular tight junction(GO:0061689)
6.4	44.5	GO:0000813	ESCRT I complex(GO:0000813)
6.3	25.3	GO:0032044	DSIF complex(GO:0032044)
6.3	119.5	GO:0036020	endolysosome membrane(GO:0036020)
6.3	50.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
6.3	56.3	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
6.0	35.9	GO:0070435	Shc-EGFR complex(GO:0070435)
5.9	53.2	GO:0072546	ER membrane protein complex(GO:0072546)
5.8	174.4	GO:0030687	preribosome, large subunit precursor(GO:0030687)
5.6	33.6	GO:0008537	proteasome activator complex(GO:0008537)
5.6	27.8	GO:0070847	core mediator complex(GO:0070847)
5.5	32.9	GO:1902560	GMP reductase complex(GO:1902560)
5.5	21.8	GO:0005846	nuclear cap binding complex(GO:0005846)
5.4	21.5	GO:0044611	nuclear pore inner ring(GO:0044611)
5.3	16.0	GO:1902636	kinociliary basal body(GO:1902636)
5.2	15.7	GO:0071020	post-spliceosomal complex(GO:0071020)
5.2	99.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
5.2	41.5	GO:0005672	transcription factor TFIIA complex(GO:0005672)
5.1	50.7	GO:0030126	COPI vesicle coat(GO:0030126)
4.9	14.8	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
4.8	77.5	GO:0016461	unconventional myosin complex(GO:0016461)
4.8	193.3	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
4.8	52.7	GO:0070765	gamma-secretase complex(GO:0070765)
4.8	38.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
4.8	109.6	GO:0005685	U1 snRNP(GO:0005685)
4.6	50.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
4.6	13.7	GO:0005608	laminin-3 complex(GO:0005608)
4.4	30.6	GO:0005956	protein kinase CK2 complex(GO:0005956)
4.4	47.9	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
4.2	21.1	GO:0098837	postsynaptic recycling endosome(GO:0098837)
4.2	29.6	GO:0000172	ribonuclease MRP complex(GO:0000172)
4.2	75.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
4.1	78.8	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
4.1	36.7	GO:0097443	sorting endosome(GO:0097443)
4.1	24.5	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
4.0	27.9	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
3.9	85.1	GO:0030127	COPII vesicle coat(GO:0030127)
3.8	42.3	GO:0022624	proteasome accessory complex(GO:0022624)
3.8	41.6	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
3.7	11.1	GO:0034685	integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
3.7	51.6	GO:0001673	male germ cell nucleus(GO:0001673)
3.6	39.9	GO:0043203	axon hillock(GO:0043203)
3.5	13.8	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
3.4	40.9	GO:0030008	TRAPP complex(GO:0030008)
3.4	17.0	GO:0071797	LUBAC complex(GO:0071797)
3.4	16.9	GO:0071986	Ragulator complex(GO:0071986)
3.4	23.7	GO:0061617	MICOS complex(GO:0061617)
3.4	30.4	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
3.4	16.8	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
3.3	53.4	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
3.2	63.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
3.1	9.4	GO:0034455	t-UTP complex(GO:0034455)
3.1	21.5	GO:0070522	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
3.0	36.2	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
2.7	86.6	GO:0016592	mediator complex(GO:0016592)
2.7	37.3	GO:0005662	DNA replication factor A complex(GO:0005662)
2.7	8.0	GO:0035370	UBC13-UEV1A complex(GO:0035370)
2.6	31.7	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
2.6	23.7	GO:0034464	BBSome(GO:0034464)
2.6	18.4	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
2.6	7.9	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
2.6	135.5	GO:0008180	COP9 signalosome(GO:0008180)
2.6	93.6	GO:0000421	autophagosome membrane(GO:0000421)
2.5	7.6	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
2.5	7.6	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
2.5	29.9	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
2.5	44.6	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
2.5	12.3	GO:0005839	proteasome core complex(GO:0005839)
2.4	24.5	GO:0097255	R2TP complex(GO:0097255)
2.4	26.9	GO:1990023	mitotic spindle midzone(GO:1990023)
2.4	61.3	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
2.3	16.4	GO:0031415	NatA complex(GO:0031415)
2.3	9.3	GO:0005687	U4 snRNP(GO:0005687)
2.3	126.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
2.2	134.9	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
2.2	24.7	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
2.2	13.4	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
2.2	31.4	GO:0036038	MKS complex(GO:0036038)
2.2	19.4	GO:0005675	holo TFIIH complex(GO:0005675)
2.1	6.4	GO:0031428	box C/D snoRNP complex(GO:0031428)
2.0	8.2	GO:0070876	SOSS complex(GO:0070876)
2.0	6.1	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
2.0	20.0	GO:0000796	condensin complex(GO:0000796)
2.0	53.8	GO:0005868	cytoplasmic dynein complex(GO:0005868)
1.9	15.3	GO:0042382	paraspeckles(GO:0042382)
1.9	7.6	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
1.8	9.2	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.8	29.3	GO:0030914	STAGA complex(GO:0030914)
1.8	27.1	GO:0000812	Swr1 complex(GO:0000812)
1.8	5.3	GO:0016938	kinesin I complex(GO:0016938)
1.7	8.7	GO:0032449	CBM complex(GO:0032449)
1.7	8.7	GO:0005602	complement component C1 complex(GO:0005602)
1.7	10.2	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
1.7	11.9	GO:0031298	replication fork protection complex(GO:0031298)
1.7	5.0	GO:0070939	Dsl1p complex(GO:0070939)
1.6	4.9	GO:0072563	endothelial microparticle(GO:0072563)
1.6	16.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.6	14.6	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
1.6	4.8	GO:0097134	Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
1.6	23.9	GO:0031080	nuclear pore outer ring(GO:0031080)
1.6	9.4	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
1.5	6.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
1.5	24.6	GO:0036452	ESCRT complex(GO:0036452)
1.5	39.9	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
1.5	12.2	GO:0070552	BRISC complex(GO:0070552)
1.5	55.8	GO:0031941	filamentous actin(GO:0031941)
1.5	4.5	GO:0030289	protein phosphatase 4 complex(GO:0030289)
1.5	71.8	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.4	7.1	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
1.4	7.1	GO:0071148	TEAD-1-YAP complex(GO:0071148)
1.4	22.3	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.4	4.1	GO:0071159	NF-kappaB complex(GO:0071159)
1.4	9.6	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.3	10.8	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
1.3	10.8	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
1.3	35.4	GO:0002080	acrosomal membrane(GO:0002080)
1.3	5.2	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
1.3	20.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
1.3	5.1	GO:0009368	endopeptidase Clp complex(GO:0009368)
1.2	93.4	GO:0005884	actin filament(GO:0005884)
1.2	10.5	GO:0005955	calcineurin complex(GO:0005955)
1.2	4.6	GO:0036449	microtubule minus-end(GO:0036449)
1.1	9.1	GO:0033276	transcription factor TFTC complex(GO:0033276)
1.1	5.6	GO:0000243	commitment complex(GO:0000243)
1.1	38.7	GO:0016469	proton-transporting two-sector ATPase complex(GO:0016469)
1.1	4.3	GO:0042587	glycogen granule(GO:0042587)
1.1	26.9	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.0	52.3	GO:0005876	spindle microtubule(GO:0005876)
1.0	4.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
1.0	9.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.0	9.1	GO:0032797	SMN complex(GO:0032797)
1.0	9.1	GO:0097431	mitotic spindle pole(GO:0097431)
1.0	6.0	GO:0030905	retromer, tubulation complex(GO:0030905)
1.0	5.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
1.0	4.9	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
1.0	2.9	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.9	11.3	GO:0042555	MCM complex(GO:0042555)
0.9	3.8	GO:0070695	FHF complex(GO:0070695)
0.9	21.5	GO:0099738	cell cortex region(GO:0099738)
0.9	4.7	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.9	73.7	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.9	19.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.9	61.6	GO:0005637	nuclear inner membrane(GO:0005637)
0.9	9.9	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.9	262.9	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.9	50.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.9	20.1	GO:0005680	anaphase-promoting complex(GO:0005680)
0.9	6.1	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.9	6.8	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.8	5.9	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.8	27.6	GO:0005871	kinesin complex(GO:0005871)
0.8	38.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.8	7.4	GO:0097470	ribbon synapse(GO:0097470)
0.8	10.6	GO:0035631	CD40 receptor complex(GO:0035631)
0.8	17.1	GO:0032420	stereocilium(GO:0032420)
0.8	16.3	GO:0000502	proteasome complex(GO:0000502)
0.8	4.1	GO:0005899	insulin receptor complex(GO:0005899)
0.8	1.6	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.8	5.6	GO:0005787	signal peptidase complex(GO:0005787)
0.8	12.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.8	14.9	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.8	168.2	GO:0001726	ruffle(GO:0001726)
0.8	3.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.8	5.4	GO:0005638	lamin filament(GO:0005638)
0.8	13.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.8	28.2	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.7	2.9	GO:0060091	kinocilium(GO:0060091)
0.7	2.2	GO:0001940	male pronucleus(GO:0001940)
0.7	14.6	GO:0032040	small-subunit processome(GO:0032040)
0.7	1.4	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.7	1.4	GO:0014802	terminal cisterna(GO:0014802)
0.7	2.1	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.7	0.7	GO:0033269	internode region of axon(GO:0033269)
0.7	35.4	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.7	26.3	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.7	5.2	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.6	10.9	GO:0000145	exocyst(GO:0000145)
0.6	81.7	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.6	4.4	GO:0030137	COPI-coated vesicle(GO:0030137)
0.6	5.7	GO:0061574	ASAP complex(GO:0061574)
0.6	8.1	GO:0016580	Sin3 complex(GO:0016580)
0.6	20.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.6	3.7	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.6	1.9	GO:0097427	microtubule bundle(GO:0097427)
0.6	3.7	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.6	3.6	GO:0032009	early phagosome(GO:0032009)
0.6	20.3	GO:0090544	BAF-type complex(GO:0090544)
0.6	6.6	GO:0042583	chromaffin granule(GO:0042583)
0.6	1.7	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.6	29.0	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.6	60.0	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.6	11.8	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.6	2.2	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.5	4.9	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.5	22.2	GO:0016235	aggresome(GO:0016235)
0.5	1.1	GO:0044232	organelle membrane contact site(GO:0044232)
0.5	9.1	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5	4.3	GO:0035861	site of double-strand break(GO:0035861)
0.5	255.4	GO:0044429	mitochondrial part(GO:0044429)
0.5	10.1	GO:0031082	BLOC complex(GO:0031082)
0.5	5.0	GO:0005686	U2 snRNP(GO:0005686)
0.5	18.5	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.5	2.5	GO:0030686	90S preribosome(GO:0030686)
0.5	49.3	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.5	18.1	GO:0043198	dendritic shaft(GO:0043198)
0.5	2.9	GO:0038201	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.5	3.9	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.5	7.7	GO:0033270	paranode region of axon(GO:0033270)
0.5	7.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.4	4.9	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.4	1.7	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.4	0.4	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.4	4.8	GO:0097225	sperm midpiece(GO:0097225)
0.4	25.8	GO:0030175	filopodium(GO:0030175)
0.4	0.7	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.4	275.2	GO:0005739	mitochondrion(GO:0005739)
0.4	8.6	GO:0005861	troponin complex(GO:0005861)
0.4	1.8	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.4	5.0	GO:0035102	PRC1 complex(GO:0035102)
0.4	47.3	GO:0030018	Z disc(GO:0030018)
0.3	2.0	GO:0031931	TORC1 complex(GO:0031931)
0.3	25.0	GO:0005643	nuclear pore(GO:0005643)
0.3	1.3	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3	9.3	GO:0005605	basal lamina(GO:0005605)
0.3	1.2	GO:0070852	cell body fiber(GO:0070852)
0.3	6.9	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.3	26.6	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.3	2.4	GO:0031105	septin complex(GO:0031105)
0.3	19.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.3	4.3	GO:0005922	connexon complex(GO:0005922)
0.3	2.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	5.2	GO:0044291	cell-cell contact zone(GO:0044291)
0.2	4.0	GO:0055038	recycling endosome membrane(GO:0055038)
0.2	23.8	GO:0043209	myelin sheath(GO:0043209)
0.2	3.6	GO:0031089	platelet dense granule lumen(GO:0031089)
0.2	5.1	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.2	0.2	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.2	62.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.2	2.7	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2	0.7	GO:0035577	azurophil granule membrane(GO:0035577)
0.2	41.5	GO:0031967	organelle envelope(GO:0031967) envelope(GO:0031975)
0.2	17.3	GO:0043197	dendritic spine(GO:0043197)
0.2	2.5	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.2	1.5	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.2	4.0	GO:0002102	podosome(GO:0002102)
0.2	0.4	GO:0089701	U2AF(GO:0089701)
0.2	8.6	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.2	10.4	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.2	1.6	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2	4.0	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.2	28.7	GO:0005874	microtubule(GO:0005874)
0.2	9.7	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.2	1.4	GO:0005579	membrane attack complex(GO:0005579)
0.2	10.5	GO:0035580	specific granule lumen(GO:0035580)
0.1	4.4	GO:0000793	condensed chromosome(GO:0000793)
0.1	12.1	GO:0005796	Golgi lumen(GO:0005796)
0.1	6.2	GO:0005901	caveola(GO:0005901)
0.1	0.4	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.1	124.9	GO:0005783	endoplasmic reticulum(GO:0005783)
0.1	4.2	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	6.0	GO:0070160	occluding junction(GO:0070160)
0.1	0.4	GO:0071546	pi-body(GO:0071546)
0.1	1.7	GO:0030426	growth cone(GO:0030426)
0.1	9.5	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.1	0.8	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1	4.8	GO:0043202	lysosomal lumen(GO:0043202)
0.1	0.7	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.7	GO:0045178	basal part of cell(GO:0045178)
0.1	0.4	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	1.4	GO:0005581	collagen trimer(GO:0005581)
0.1	87.0	GO:0070062	extracellular exosome(GO:0070062)
0.1	0.4	GO:0030017	sarcomere(GO:0030017)
0.0	2.9	GO:0031225	anchored component of membrane(GO:0031225)
0.0	1.3	GO:0005604	basement membrane(GO:0005604)
0.0	0.6	GO:0005811	lipid particle(GO:0005811)
0.0	1.5	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.5	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.0	1.5	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.3	GO:0001533	cornified envelope(GO:0001533)
0.0	0.6	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	2.7	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	3.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	1.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.6	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	17.0	GO:0005856	cytoskeleton(GO:0005856)
0.0	0.1	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.4	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	1.4	GO:0005929	cilium(GO:0005929)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
41.6	124.7	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
27.5	82.4	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
18.4	55.3	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
17.6	52.7	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
14.6	160.3	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
13.6	95.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
13.4	93.5	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
12.3	37.0	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
12.2	48.6	GO:0032217	riboflavin transporter activity(GO:0032217)
12.0	36.1	GO:0035539	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
10.5	52.3	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
10.2	30.6	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
9.8	29.4	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
9.4	47.2	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
9.4	46.9	GO:0043023	ribosomal large subunit binding(GO:0043023)
8.9	89.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
8.2	32.8	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
8.0	39.9	GO:0061676	importin-alpha family protein binding(GO:0061676)
8.0	39.8	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
7.6	38.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
7.6	68.3	GO:0035174	histone serine kinase activity(GO:0035174)
7.2	35.9	GO:0015140	malate transmembrane transporter activity(GO:0015140)
7.2	28.7	GO:0052827	inositol pentakisphosphate phosphatase activity(GO:0052827)
7.1	49.9	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
7.0	27.9	GO:0016748	succinyltransferase activity(GO:0016748)
6.5	19.4	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
6.4	19.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
6.0	35.9	GO:0048408	epidermal growth factor binding(GO:0048408)
6.0	17.9	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
5.8	40.6	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
5.8	17.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
5.7	17.2	GO:0030984	kininogen binding(GO:0030984)
5.7	34.2	GO:0016531	copper chaperone activity(GO:0016531)
5.6	56.5	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
5.5	22.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
5.5	33.0	GO:1990446	U1 snRNP binding(GO:1990446)
5.5	43.9	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
5.5	32.9	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
5.4	124.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
5.3	31.8	GO:0044388	small protein activating enzyme binding(GO:0044388)
5.3	15.9	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
5.3	26.4	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
4.9	29.5	GO:1901612	cardiolipin binding(GO:1901612)
4.8	33.6	GO:0061133	endopeptidase activator activity(GO:0061133)
4.7	23.6	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
4.7	111.9	GO:0008327	methyl-CpG binding(GO:0008327)
4.6	101.5	GO:0000339	RNA cap binding(GO:0000339)
4.6	95.9	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
4.4	232.9	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
4.4	48.3	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
4.2	34.0	GO:0032050	clathrin heavy chain binding(GO:0032050)
4.2	75.2	GO:0001054	RNA polymerase I activity(GO:0001054)
4.1	87.0	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
4.1	78.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
4.1	24.5	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
4.0	11.9	GO:0016731	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
3.9	23.2	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
3.8	26.9	GO:0050815	phosphoserine binding(GO:0050815)
3.7	33.6	GO:0008158	hedgehog receptor activity(GO:0008158)
3.7	73.1	GO:0070628	proteasome binding(GO:0070628)
3.6	10.9	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
3.5	14.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
3.4	3.4	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
3.4	50.7	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
3.4	124.1	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
3.3	16.6	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
3.3	13.2	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
3.2	171.2	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
3.2	19.2	GO:0042296	ISG15 transferase activity(GO:0042296)
3.2	12.6	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
3.1	21.5	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
3.0	105.8	GO:0001671	ATPase activator activity(GO:0001671)
3.0	93.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
3.0	18.0	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
3.0	23.8	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
3.0	14.8	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
2.9	23.2	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
2.9	40.4	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
2.9	14.3	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
2.8	14.2	GO:0002046	opsin binding(GO:0002046)
2.8	11.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
2.8	11.2	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
2.8	83.7	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
2.8	8.3	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
2.7	8.2	GO:0034511	U3 snoRNA binding(GO:0034511)
2.7	16.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
2.7	10.7	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
2.6	34.2	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
2.6	7.9	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
2.6	96.0	GO:0044183	protein binding involved in protein folding(GO:0044183)
2.5	10.1	GO:0035473	lipase binding(GO:0035473)
2.5	7.6	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
2.5	10.0	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
2.5	32.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
2.4	24.1	GO:0031386	protein tag(GO:0031386)
2.4	236.7	GO:0008307	structural constituent of muscle(GO:0008307)
2.4	2.4	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.4	26.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
2.4	23.5	GO:0030911	TPR domain binding(GO:0030911)
2.3	2.3	GO:0070990	snRNP binding(GO:0070990)
2.3	9.3	GO:0034046	poly(G) binding(GO:0034046)
2.3	7.0	GO:0042134	rRNA primary transcript binding(GO:0042134)
2.2	9.0	GO:0005046	KDEL sequence binding(GO:0005046)
2.2	55.9	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
2.2	11.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
2.2	24.3	GO:0046790	virion binding(GO:0046790)
2.2	6.6	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
2.1	4.2	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
2.1	6.3	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
2.1	6.2	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
2.1	8.3	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
2.1	16.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
2.1	10.3	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
2.0	38.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
2.0	76.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
2.0	8.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
2.0	33.3	GO:0003688	DNA replication origin binding(GO:0003688)
1.9	23.3	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
1.9	5.7	GO:0019961	interferon binding(GO:0019961)
1.9	30.3	GO:0017160	Ral GTPase binding(GO:0017160)
1.9	54.6	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
1.9	29.9	GO:0004526	ribonuclease P activity(GO:0004526)
1.9	11.2	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
1.9	29.7	GO:0016783	sulfurtransferase activity(GO:0016783)
1.8	10.9	GO:0051022	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
1.8	5.4	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
1.8	5.3	GO:0000104	succinate dehydrogenase activity(GO:0000104)
1.8	49.5	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.8	14.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
1.7	27.8	GO:0042809	vitamin D receptor binding(GO:0042809)
1.7	5.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.7	30.9	GO:0005522	profilin binding(GO:0005522)
1.7	3.4	GO:0016882	cyclo-ligase activity(GO:0016882)
1.7	18.5	GO:0043047	single-stranded telomeric DNA binding(GO:0043047)
1.7	18.5	GO:0032036	myosin heavy chain binding(GO:0032036)
1.7	6.7	GO:0032810	sterol response element binding(GO:0032810)
1.7	5.0	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.7	1.7	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
1.7	5.0	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
1.6	6.6	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.6	11.4	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.6	16.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.6	116.0	GO:0019003	GDP binding(GO:0019003)
1.6	4.8	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
1.6	11.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.6	6.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
1.6	20.3	GO:0031489	myosin V binding(GO:0031489)
1.6	3.1	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
1.6	18.6	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
1.6	18.6	GO:0030515	snoRNA binding(GO:0030515)
1.5	12.3	GO:0003993	acid phosphatase activity(GO:0003993)
1.5	47.8	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.5	43.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
1.5	23.9	GO:0070513	death domain binding(GO:0070513)
1.5	4.4	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.5	7.4	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
1.5	19.2	GO:0004985	opioid receptor activity(GO:0004985)
1.5	126.9	GO:0051082	unfolded protein binding(GO:0051082)
1.4	8.6	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
1.4	4.3	GO:0003684	damaged DNA binding(GO:0003684)
1.4	5.4	GO:0030620	U2 snRNA binding(GO:0030620)
1.3	86.2	GO:0003743	translation initiation factor activity(GO:0003743)
1.3	14.8	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
1.3	5.3	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
1.3	18.6	GO:0008170	N-methyltransferase activity(GO:0008170)
1.3	7.9	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.3	25.1	GO:0097602	cullin family protein binding(GO:0097602)
1.3	7.9	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
1.3	14.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
1.3	2.6	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
1.3	1.3	GO:0051185	coenzyme transporter activity(GO:0051185)
1.3	66.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
1.2	64.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.2	27.8	GO:0070008	serine-type exopeptidase activity(GO:0070008)
1.2	14.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
1.2	4.7	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
1.2	10.5	GO:0030346	protein phosphatase 2B binding(GO:0030346)
1.2	2.3	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.2	20.8	GO:0043495	protein anchor(GO:0043495)
1.1	3.4	GO:0046921	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
1.1	31.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
1.1	2.2	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661) Rab geranylgeranyltransferase activity(GO:0004663)
1.1	2.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
1.1	17.7	GO:0005537	mannose binding(GO:0005537)
1.1	13.8	GO:0016018	cyclosporin A binding(GO:0016018)
1.1	3.2	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
1.1	5.3	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
1.1	8.4	GO:0071933	Arp2/3 complex binding(GO:0071933)
1.0	3.1	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
1.0	43.6	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
1.0	4.1	GO:0097100	oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) supercoiled DNA binding(GO:0097100)
1.0	3.1	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
1.0	7.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
1.0	6.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
1.0	12.2	GO:0008143	poly(A) binding(GO:0008143)
1.0	13.2	GO:0008179	adenylate cyclase binding(GO:0008179)
1.0	2.0	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
1.0	11.9	GO:0045505	dynein intermediate chain binding(GO:0045505)
1.0	7.9	GO:0005049	nuclear export signal receptor activity(GO:0005049)
1.0	9.8	GO:0001055	RNA polymerase II activity(GO:0001055)
1.0	3.9	GO:0033906	protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
1.0	4.8	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
1.0	4.8	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.9	12.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.9	22.3	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.9	13.0	GO:0019966	interleukin-1 binding(GO:0019966)
0.9	70.9	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.9	11.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.9	1.8	GO:0008384	IkappaB kinase activity(GO:0008384)
0.9	79.6	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.9	87.6	GO:0003697	single-stranded DNA binding(GO:0003697)
0.9	40.4	GO:0004527	exonuclease activity(GO:0004527)
0.9	26.8	GO:0017091	AU-rich element binding(GO:0017091)
0.9	6.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.9	7.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.9	62.8	GO:0008565	protein transporter activity(GO:0008565)
0.9	41.7	GO:0031491	nucleosome binding(GO:0031491)
0.9	19.9	GO:0017025	TBP-class protein binding(GO:0017025)
0.9	30.3	GO:0003785	actin monomer binding(GO:0003785)
0.8	10.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.8	9.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.8	8.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.8	15.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.8	6.5	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.8	23.4	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.8	7.2	GO:0051400	BH domain binding(GO:0051400)
0.8	3.1	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.8	262.3	GO:0005525	GTP binding(GO:0005525)
0.8	2.3	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.8	58.8	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.7	16.5	GO:0008242	omega peptidase activity(GO:0008242)
0.7	3.7	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.7	3.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.7	3.7	GO:0097016	L27 domain binding(GO:0097016)
0.7	2.2	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.7	5.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.7	18.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.7	2.9	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.7	28.9	GO:0003777	microtubule motor activity(GO:0003777)
0.7	42.5	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.7	8.1	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.7	2.7	GO:0015232	heme transporter activity(GO:0015232)
0.7	4.0	GO:0008046	axon guidance receptor activity(GO:0008046)
0.7	3.3	GO:0004925	prolactin receptor activity(GO:0004925)
0.7	5.9	GO:0043422	protein kinase B binding(GO:0043422)
0.6	4.5	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.6	2.6	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.6	10.1	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.6	5.0	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.6	8.6	GO:0031014	troponin T binding(GO:0031014)
0.6	4.8	GO:0035173	histone kinase activity(GO:0035173)
0.6	8.9	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.6	0.6	GO:0051731	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.6	21.6	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.6	1.7	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.6	5.8	GO:0070182	DNA polymerase binding(GO:0070182)
0.6	2.3	GO:0016972	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.6	10.7	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.6	3.9	GO:1990459	transferrin receptor binding(GO:1990459)
0.6	3.9	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.6	2.8	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.5	3.8	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.5	4.9	GO:0001056	RNA polymerase III activity(GO:0001056)
0.5	8.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5	2.7	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.5	1.1	GO:0051373	FATZ binding(GO:0051373)
0.5	22.1	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.5	0.5	GO:0019826	oxygen sensor activity(GO:0019826)
0.5	55.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.5	11.1	GO:0042171	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.5	2.5	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.5	3.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.5	7.5	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.5	5.5	GO:0101005	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.5	3.0	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.5	1.5	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.5	3.9	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.5	2.5	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.5	11.2	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.5	9.0	GO:0048365	Rac GTPase binding(GO:0048365)
0.5	4.3	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.5	10.6	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.5	5.5	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.5	3.7	GO:0004064	arylesterase activity(GO:0004064)
0.5	0.5	GO:0016781	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.5	6.8	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.5	5.0	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.4	53.7	GO:0005262	calcium channel activity(GO:0005262)
0.4	39.8	GO:0019905	syntaxin binding(GO:0019905)
0.4	15.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.4	47.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.4	14.2	GO:0000049	tRNA binding(GO:0000049)
0.4	10.2	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4	23.9	GO:0015399	primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.4	4.8	GO:0016866	intramolecular transferase activity(GO:0016866)
0.4	7.7	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4	4.7	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.4	6.4	GO:0070034	telomerase RNA binding(GO:0070034)
0.4	5.1	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.4	4.5	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.4	1.6	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.4	8.1	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4	2.0	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.4	2.0	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.4	2.4	GO:0019776	Atg8 ligase activity(GO:0019776)
0.4	0.4	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.4	1.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.4	1.2	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.4	1.9	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.4	40.4	GO:0047485	protein N-terminus binding(GO:0047485)
0.4	9.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.4	11.6	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.4	4.6	GO:0017166	vinculin binding(GO:0017166)
0.4	1.1	GO:0017130	poly(C) RNA binding(GO:0017130)
0.3	6.9	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.3	14.6	GO:0045182	translation regulator activity(GO:0045182)
0.3	0.6	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
0.3	9.7	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3	3.7	GO:0031593	polyubiquitin binding(GO:0031593)
0.3	4.3	GO:0005243	gap junction channel activity(GO:0005243)
0.3	2.7	GO:0060229	phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.3	106.5	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.3	91.5	GO:0045296	cadherin binding(GO:0045296)
0.3	2.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3	9.1	GO:0000149	SNARE binding(GO:0000149)
0.3	52.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.3	17.5	GO:0009055	electron carrier activity(GO:0009055)
0.3	3.5	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.3	2.1	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.3	1.3	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.3	4.6	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.3	1.5	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.2	7.5	GO:0001972	retinoic acid binding(GO:0001972)
0.2	9.9	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2	1.1	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.2	3.1	GO:0043015	gamma-tubulin binding(GO:0043015)
0.2	1.3	GO:0003998	acylphosphatase activity(GO:0003998)
0.2	1.1	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2	1.7	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2	0.4	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.2	0.6	GO:0002113	interleukin-33 binding(GO:0002113)
0.2	5.3	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.2	10.5	GO:0008276	protein methyltransferase activity(GO:0008276)
0.2	5.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2	1.5	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.2	4.1	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2	2.1	GO:0030331	estrogen receptor binding(GO:0030331)
0.2	0.9	GO:0039706	co-receptor binding(GO:0039706)
0.2	0.4	GO:0048039	ubiquinone binding(GO:0048039)
0.2	0.6	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.2	3.1	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.2	8.0	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2	1.6	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2	3.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.2	1.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.2	11.0	GO:0030165	PDZ domain binding(GO:0030165)
0.2	1.4	GO:0034062	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.2	5.6	GO:0002039	p53 binding(GO:0002039)
0.2	0.8	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.2	40.7	GO:0046873	metal ion transmembrane transporter activity(GO:0046873)
0.2	9.2	GO:0034212	peptide N-acetyltransferase activity(GO:0034212)
0.2	1.3	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.2	2.0	GO:0051787	misfolded protein binding(GO:0051787)
0.2	20.2	GO:0005179	hormone activity(GO:0005179)
0.2	11.4	GO:0044325	ion channel binding(GO:0044325)
0.2	1.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	1.8	GO:0015248	sterol transporter activity(GO:0015248)
0.1	26.5	GO:0004857	enzyme inhibitor activity(GO:0004857)
0.1	0.4	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	3.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	4.3	GO:0019239	deaminase activity(GO:0019239)
0.1	1.4	GO:0019841	retinol binding(GO:0019841)
0.1	3.5	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1	4.2	GO:0004407	histone deacetylase activity(GO:0004407)
0.1	0.5	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	1.9	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	0.3	GO:0004040	amidase activity(GO:0004040)
0.1	9.3	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.4	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.9	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.1	0.3	GO:0070905	serine binding(GO:0070905)
0.1	1.6	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	0.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	65.8	GO:0005509	calcium ion binding(GO:0005509)
0.1	1.7	GO:0043531	ADP binding(GO:0043531)
0.1	0.1	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1	1.8	GO:0031005	filamin binding(GO:0031005)
0.1	0.6	GO:0052655	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1	2.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	96.8	GO:0003723	RNA binding(GO:0003723)
0.1	1.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	9.4	GO:0015631	tubulin binding(GO:0015631)
0.1	0.3	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1	0.3	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.1	18.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	0.2	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1	6.3	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.1	5.4	GO:0016887	ATPase activity(GO:0016887)
0.1	2.3	GO:0005507	copper ion binding(GO:0005507)
0.1	4.1	GO:0051015	actin filament binding(GO:0051015)
0.1	0.7	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	2.9	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1	0.3	GO:0016499	orexin receptor activity(GO:0016499)
0.1	0.5	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	1.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.7	GO:0043236	laminin binding(GO:0043236)
0.1	1.8	GO:0003682	chromatin binding(GO:0003682)
0.1	0.4	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.3	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.8	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	6.0	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.3	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	1.0	GO:0005109	frizzled binding(GO:0005109)
0.0	0.7	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0	0.2	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	1.5	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.4	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	23.7	GO:0042802	identical protein binding(GO:0042802)
0.0	0.6	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	2.3	GO:0008237	metallopeptidase activity(GO:0008237)
0.0	4.3	GO:0005198	structural molecule activity(GO:0005198)
0.0	0.1	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.0	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0051378	amine binding(GO:0043176) serotonin binding(GO:0051378)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.2	114.6	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
5.4	141.7	PID ARF 3PATHWAY	Arf1 pathway
3.1	130.5	PID EPHA FWDPATHWAY	EPHA forward signaling
3.0	84.9	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
3.0	168.3	PID AURORA A PATHWAY	Aurora A signaling
2.8	73.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
2.8	95.9	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
2.5	92.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
2.3	24.8	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
2.2	93.6	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
2.2	50.7	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
2.1	114.6	PID FOXM1 PATHWAY	FOXM1 transcription factor network
2.0	46.9	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
1.8	34.6	PID ALK2 PATHWAY	ALK2 signaling events
1.5	27.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
1.3	32.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
1.3	3.8	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
1.3	66.7	PID ATR PATHWAY	ATR signaling pathway
1.2	60.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
1.2	21.6	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
1.2	8.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
1.2	37.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
1.1	10.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
1.1	42.5	PID MYC PATHWAY	C-MYC pathway
1.1	52.8	PID AURORA B PATHWAY	Aurora B signaling
1.1	25.7	PID RAC1 PATHWAY	RAC1 signaling pathway
1.0	30.0	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
1.0	22.5	PID S1P S1P1 PATHWAY	S1P1 pathway
0.9	27.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.8	13.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.7	25.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.7	22.7	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.7	11.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.7	41.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.7	12.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.6	18.7	PID EPHB FWD PATHWAY	EPHB forward signaling
0.6	1.9	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.6	21.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.6	35.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.6	13.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.6	10.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.5	12.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.5	12.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.5	6.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.5	48.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.5	19.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.5	5.8	PID NECTIN PATHWAY	Nectin adhesion pathway
0.4	15.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.4	4.3	PID ALK1 PATHWAY	ALK1 signaling events
0.4	12.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.4	23.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.4	24.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.4	11.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.4	12.8	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.4	28.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.4	5.4	ST G ALPHA S PATHWAY	G alpha s Pathway
0.4	23.6	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.4	20.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.3	4.7	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.3	5.0	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.3	3.7	PID ERBB4 PATHWAY	ErbB4 signaling events
0.3	3.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.3	2.2	PID IFNG PATHWAY	IFN-gamma pathway
0.3	5.2	PID INSULIN PATHWAY	Insulin Pathway
0.2	56.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	43.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	9.0	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.2	2.2	PID FOXO PATHWAY	FoxO family signaling
0.2	5.7	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.2	8.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.2	5.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.2	6.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.2	0.8	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.2	7.4	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.1	2.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	1.9	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	2.4	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	4.1	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	6.4	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	0.9	PID BARD1 PATHWAY	BARD1 signaling events
0.1	2.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	2.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	0.3	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	7.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.4	75.7	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
7.4	44.5	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
7.0	204.1	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
6.6	125.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
5.9	94.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
5.7	465.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
5.7	125.8	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
5.6	88.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
4.9	301.2	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
4.8	72.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
4.6	23.1	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
4.4	96.9	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
4.3	85.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
4.2	267.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
4.2	70.6	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
4.1	41.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
4.0	16.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
4.0	72.0	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
3.8	61.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
3.7	3.7	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
3.5	59.7	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
3.4	271.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
3.4	16.8	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
3.2	45.3	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
3.0	88.1	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
3.0	41.8	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
2.9	87.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
2.9	154.2	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
2.9	54.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
2.8	33.7	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
2.8	108.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
2.7	48.2	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
2.7	69.6	REACTOME KINESINS	Genes involved in Kinesins
2.7	82.7	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
2.4	23.6	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
2.1	34.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
2.0	48.9	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
2.0	24.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.9	48.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
1.8	42.9	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
1.7	41.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
1.7	152.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
1.6	30.9	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
1.6	40.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
1.6	9.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
1.5	43.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
1.5	24.0	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
1.5	32.2	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
1.4	32.6	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
1.4	30.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
1.3	26.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.3	71.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
1.3	49.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
1.2	29.7	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
1.2	4.9	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
1.2	13.0	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
1.2	2.3	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
1.1	9.0	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
1.1	2.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
1.1	25.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
1.1	41.6	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
1.1	8.7	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
1.1	20.7	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
1.1	7.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
1.1	176.2	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.0	22.8	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
1.0	25.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
1.0	22.9	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.9	27.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.9	7.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.9	82.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.8	21.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.8	54.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.8	15.1	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.8	13.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.8	8.7	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.7	30.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.7	2.9	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.7	40.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.7	8.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.7	22.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6	10.8	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.6	67.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.6	14.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.5	17.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.5	5.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.5	13.7	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.5	16.0	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.4	17.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.4	6.1	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.4	20.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.4	7.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.4	6.9	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.4	27.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.4	6.4	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.4	10.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4	6.5	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3	8.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.3	3.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.3	3.7	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.3	3.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.3	1.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3	19.4	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.2	7.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.2	5.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	4.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	16.1	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2	3.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	6.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.2	5.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.2	3.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	3.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.2	8.2	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.2	3.8	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.2	3.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.2	3.0	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.2	8.8	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.2	38.7	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.2	8.6	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.2	6.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	3.9	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.1	4.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	6.1	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	3.0	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	7.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	2.8	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	9.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	1.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	0.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	0.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	4.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	1.5	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	1.7	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	4.4	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	2.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.8	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	1.0	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.5	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.3	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	1.3	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	2.5	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.2	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.4	REACTOME AMYLOIDS	Genes involved in Amyloids

Results for ETV1_ERF_FEV_ELF1

Z-value: 2.92

Motif logo

Transcription factors associated with ETV1_ERF_FEV_ELF1

Activity-expression correlation:

Activity profile of ETV1_ERF_FEV_ELF1 motif

Sorted Z-values of ETV1_ERF_FEV_ELF1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV1_ERF_FEV_ELF1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: