averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
EZH2 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000106462.6	enhancer of zeste 2 polycomb repressive complex 2 subunit

Gene	Promoter	Pearson corr. coef.	P-value	Plot
EZH2	hg19_v2_chr7_-_148580563_148580601	-0.55	9.0e-19	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_-_111781610 Show fit	67.93	ENST00000525823.1	CRYAB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	crystallin, alpha B
chr11_-_111781554 Show fit	54.71	ENST00000526167.1 ENST00000528961.1	CRYAB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	crystallin, alpha B
chr11_-_111781454 Show fit	54.60	ENST00000533280.1	CRYAB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	crystallin, alpha B
chr3_+_115342159 Show fit	52.03	ENST00000305124.6	GAP43 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	growth associated protein 43
chr3_+_115342349 Show fit	49.67	ENST00000393780.3	GAP43 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	growth associated protein 43
chr15_+_43885252 Show fit	35.15	ENST00000453782.1 ENST00000300283.6 ENST00000437924.1 ENST00000450086.2	CKMT1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	creatine kinase, mitochondrial 1B
chr14_-_60337684 Show fit	32.23	ENST00000267484.5	RTN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	reticulon 1
chrX_+_103031421 Show fit	31.50	ENST00000433491.1 ENST00000418604.1 ENST00000443502.1	PLP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteolipid protein 1
chr15_+_43985084 Show fit	30.99	ENST00000434505.1 ENST00000411750.1	CKMT1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	creatine kinase, mitochondrial 1A
chr14_-_21490958 Show fit	28.99	ENST00000554104.1	NDRG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NDRG family member 2
chr12_+_79258444 Show fit	28.79	ENST00000261205.4	SYT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptotagmin I
chr12_-_45269430 Show fit	28.68	ENST00000395487.2	NELL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NEL-like 2 (chicken)
chr3_-_195310802 Show fit	28.41	ENST00000421243.1 ENST00000453131.1	APOD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein D
chr1_+_160097462 Show fit	27.51	ENST00000447527.1	ATP1A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr14_-_21490653 Show fit	26.71	ENST00000449431.2	NDRG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NDRG family member 2
chr3_+_111717511 Show fit	26.34	ENST00000478951.1 ENST00000393917.2	TAGLN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transgelin 3
chr12_+_79258547 Show fit	26.19	ENST00000457153.2	SYT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptotagmin I
chr5_-_73937244 Show fit	25.85	ENST00000302351.4 ENST00000510316.1 ENST00000508331.1	ENC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ectodermal-neural cortex 1 (with BTB domain)
chr4_-_16900242 Show fit	25.40	ENST00000502640.1 ENST00000506732.1	LDB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain binding 2
chr12_+_66218212 Show fit	25.04	ENST00000393578.3 ENST00000425208.2 ENST00000536545.1 ENST00000354636.3	HMGA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group AT-hook 2
chr8_-_27115903 Show fit	23.82	ENST00000350889.4 ENST00000519997.1 ENST00000519614.1 ENST00000522908.1 ENST00000265770.7	STMN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stathmin-like 4
chr14_-_21491305 Show fit	23.77	ENST00000554531.1	NDRG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NDRG family member 2
chr8_-_18666360 Show fit	23.38	ENST00000286485.8	PSD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pleckstrin and Sec7 domain containing 3
chr11_-_111782484 Show fit	22.93	ENST00000533971.1	CRYAB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	crystallin, alpha B
chr2_-_55277654 Show fit	22.84	ENST00000337526.6 ENST00000317610.7 ENST00000357732.4	RTN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	reticulon 4
chr14_-_21490590 Show fit	22.64	ENST00000557633.1	NDRG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NDRG family member 2
chr15_+_43886057 Show fit	22.30	ENST00000441322.1 ENST00000413657.2 ENST00000453733.1	CKMT1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	creatine kinase, mitochondrial 1B
chr11_-_133402410 Show fit	22.18	ENST00000524381.1	OPCML Links Ensembl NCBI GeneCards UniProt NextProt Show fit	opioid binding protein/cell adhesion molecule-like
chr13_-_67804445 Show fit	22.03	ENST00000456367.1 ENST00000377861.3 ENST00000544246.1	PCDH9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin 9
chr1_+_169077172 Show fit	21.06	ENST00000499679.3	ATP1B1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr12_-_91576561 Show fit	20.74	ENST00000547568.2 ENST00000552962.1	DCN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	decorin
chr8_+_80523962 Show fit	20.72	ENST00000518491.1	STMN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stathmin-like 2
chr5_+_92919043 Show fit	20.63	ENST00000327111.3	NR2F1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 2, group F, member 1
chrX_+_103031758 Show fit	20.59	ENST00000303958.2 ENST00000361621.2	PLP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteolipid protein 1
chr8_-_27468842 Show fit	20.02	ENST00000523500.1	CLU Links Ensembl NCBI GeneCards UniProt NextProt Show fit	clusterin
chr4_-_16900410 Show fit	19.92	ENST00000304523.5	LDB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain binding 2
chr4_-_153457197 Show fit	19.89	ENST00000281708.4	FBXW7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr16_-_29910853 Show fit	19.87	ENST00000308713.5	SEZ6L2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	seizure related 6 homolog (mouse)-like 2
chr15_+_43809797 Show fit	19.51	ENST00000399453.1 ENST00000300231.5	MAP1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule-associated protein 1A
chr4_+_158141806 Show fit	19.49	ENST00000393815.2	GRIA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, ionotropic, AMPA 2
chr4_-_16900184 Show fit	19.47	ENST00000515064.1	LDB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain binding 2
chr14_-_21490417 Show fit	18.99	ENST00000556366.1	NDRG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NDRG family member 2
chr4_+_158141843 Show fit	18.97	ENST00000509417.1 ENST00000296526.7	GRIA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, ionotropic, AMPA 2
chr1_-_177134024 Show fit	18.92	ENST00000367654.3	ASTN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	astrotactin 1
chr2_-_55277692 Show fit	18.83	ENST00000394611.2	RTN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	reticulon 4
chr5_+_140749803 Show fit	18.77	ENST00000576222.1	PCDHGB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin gamma subfamily B, 3
chr4_-_16900217 Show fit	18.57	ENST00000441778.2	LDB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain binding 2
chr6_-_74161977 Show fit	18.36	ENST00000370318.1 ENST00000370315.3	MB21D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Mab-21 domain containing 1
chr14_-_21270995 Show fit	18.33	ENST00000555698.1 ENST00000397970.4 ENST00000340900.3	RNASE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonuclease, RNase A family, 1 (pancreatic)
chr4_+_156588249 Show fit	18.18	ENST00000393832.3	GUCY1A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	guanylate cyclase 1, soluble, alpha 3
chrX_-_13835461 Show fit	18.03	ENST00000316715.4 ENST00000356942.5	GPM6B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glycoprotein M6B
chr17_-_7123021 Show fit	17.92	ENST00000399510.2	DLG4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	discs, large homolog 4 (Drosophila)
chr5_-_146461027 Show fit	17.86	ENST00000394410.2 ENST00000508267.1 ENST00000504198.1	PPP2R2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2, regulatory subunit B, beta
chr1_-_57045228 Show fit	17.68	ENST00000371250.3	PPAP2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidic acid phosphatase type 2B
chr7_-_124405681 Show fit	17.38	ENST00000303921.2	GPR37 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 37 (endothelin receptor type B-like)
chr4_+_158141899 Show fit	17.27	ENST00000264426.9 ENST00000506284.1	GRIA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, ionotropic, AMPA 2
chr1_-_156399184 Show fit	17.17	ENST00000368243.1 ENST00000357975.4 ENST00000310027.5 ENST00000400991.2	C1orf61 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 61
chrX_+_69282303 Show fit	17.10	ENST00000338352.2	OTUD6A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	OTU domain containing 6A
chr3_+_111717600 Show fit	17.07	ENST00000273368.4	TAGLN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transgelin 3
chr12_+_175930 Show fit	16.60	ENST00000538872.1 ENST00000326261.4	IQSEC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	IQ motif and Sec7 domain 3
chr12_-_91576429 Show fit	16.53	ENST00000552145.1 ENST00000546745.1	DCN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	decorin
chr12_+_7167980 Show fit	16.52	ENST00000360817.5 ENST00000402681.3	C1S Links Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, s subcomponent
chr15_+_78730622 Show fit	16.51	ENST00000560440.1	IREB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	iron-responsive element binding protein 2
chr3_+_147127142 Show fit	16.48	ENST00000282928.4	ZIC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Zic family member 1
chr14_-_45431091 Show fit	16.48	ENST00000579157.1 ENST00000396128.4 ENST00000556500.1	KLHL28 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kelch-like family member 28
chr1_+_50574585 Show fit	16.47	ENST00000371824.1 ENST00000371823.4	ELAVL4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ELAV like neuron-specific RNA binding protein 4
chr19_-_49149553 Show fit	16.24	ENST00000084798.4	CA11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	carbonic anhydrase XI
chr15_+_43985725 Show fit	16.21	ENST00000413453.2	CKMT1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	creatine kinase, mitochondrial 1A
chr1_-_177133818 Show fit	16.13	ENST00000424564.2 ENST00000361833.2	ASTN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	astrotactin 1
chr16_-_21289627 Show fit	16.01	ENST00000396023.2 ENST00000415987.2	CRYM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	crystallin, mu
chr16_-_31085514 Show fit	15.80	ENST00000300849.4	ZNF668 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 668
chr1_-_145076186 Show fit	15.55	ENST00000369348.3	PDE4DIP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 4D interacting protein
chr12_-_50294033 Show fit	15.50	ENST00000552669.1	FAIM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Fas apoptotic inhibitory molecule 2
chr5_-_35230434 Show fit	15.43	ENST00000504500.1	PRLR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolactin receptor
chr7_-_38671098 Show fit	15.20	ENST00000356264.2	AMPH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	amphiphysin
chr6_+_29624862 Show fit	15.13	ENST00000376894.4	MOG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin oligodendrocyte glycoprotein
chr3_+_111718036 Show fit	14.75	ENST00000455401.2	TAGLN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transgelin 3
chr6_+_29624898 Show fit	14.62	ENST00000396704.3 ENST00000483013.1 ENST00000490427.1 ENST00000416766.2 ENST00000376891.4 ENST00000376898.3 ENST00000396701.2 ENST00000494692.1 ENST00000431798.2	MOG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin oligodendrocyte glycoprotein
chr9_+_87284622 Show fit	14.60	ENST00000395882.1	NTRK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neurotrophic tyrosine kinase, receptor, type 2
chr1_+_209859510 Show fit	14.55	ENST00000367028.2 ENST00000261465.1	HSD11B1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid (11-beta) dehydrogenase 1
chr1_+_65775204 Show fit	14.29	ENST00000371069.4	DNAJC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily C, member 6
chr6_+_29624758 Show fit	14.26	ENST00000376917.3 ENST00000376902.3 ENST00000533330.2 ENST00000376888.2	MOG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin oligodendrocyte glycoprotein
chr1_+_2005425 Show fit	14.10	ENST00000461106.2	PRKCZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase C, zeta
chr1_-_182361327 Show fit	14.08	ENST00000331872.6 ENST00000311223.5	GLUL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate-ammonia ligase
chr18_-_40695604 Show fit	13.97	ENST00000590910.1 ENST00000326695.5 ENST00000589109.1 ENST00000282028.4	RIT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras-like without CAAX 2
chr12_-_45270151 Show fit	13.96	ENST00000429094.2	NELL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NEL-like 2 (chicken)
chr14_+_45431379 Show fit	13.90	ENST00000361577.3 ENST00000361462.2 ENST00000382233.2	FAM179B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 179, member B
chr11_+_27062272 Show fit	13.89	ENST00000529202.1 ENST00000533566.1	BBOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr13_+_113633620 Show fit	13.85	ENST00000421756.1 ENST00000375601.3	MCF2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MCF.2 cell line derived transforming sequence-like
chr1_+_2036149 Show fit	13.75	ENST00000482686.1 ENST00000400920.1 ENST00000486681.1	PRKCZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase C, zeta
chr8_-_27115931 Show fit	13.64	ENST00000523048.1	STMN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stathmin-like 4
chr5_+_36608422 Show fit	13.63	ENST00000381918.3	SLC1A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_-_42498231 Show fit	13.62	ENST00000602133.1	ATP1A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr12_-_45270077 Show fit	13.56	ENST00000551601.1 ENST00000549027.1 ENST00000452445.2	NELL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NEL-like 2 (chicken)
chr1_+_2004901 Show fit	13.52	ENST00000400921.2	PRKCZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase C, zeta
chr19_+_35630926 Show fit	13.48	ENST00000588081.1 ENST00000589121.1	FXYD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 1
chr1_+_54519242 Show fit	13.42	ENST00000234827.1	TCEANC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription elongation factor A (SII) N-terminal and central domain containing 2
chr2_+_210288760 Show fit	13.42	ENST00000199940.6	MAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule-associated protein 2
chr7_-_100844193 Show fit	13.32	ENST00000440203.2 ENST00000379423.3 ENST00000223114.4	MOGAT3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	monoacylglycerol O-acyltransferase 3
chr1_-_182360918 Show fit	13.30	ENST00000339526.4	GLUL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate-ammonia ligase
chr12_-_91576750 Show fit	13.14	ENST00000228329.5 ENST00000303320.3 ENST00000052754.5	DCN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	decorin
chr7_-_137028534 Show fit	13.10	ENST00000348225.2	PTN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pleiotrophin
chr5_+_161275320 Show fit	13.09	ENST00000437025.2	GABRA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr4_+_156588115 Show fit	12.82	ENST00000455639.2	GUCY1A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	guanylate cyclase 1, soluble, alpha 3
chr18_-_53177984 Show fit	12.82	ENST00000543082.1	TCF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor 4
chr1_-_163172625 Show fit	12.68	ENST00000527988.1 ENST00000531476.1 ENST00000530507.1	RGS5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	regulator of G-protein signaling 5
chr7_-_22233442 Show fit	12.65	ENST00000401957.2	RAPGEF5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rap guanine nucleotide exchange factor (GEF) 5
chr22_-_50524298 Show fit	12.48	ENST00000311597.5	MLC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	megalencephalic leukoencephalopathy with subcortical cysts 1
chr9_+_124062071 Show fit	12.39	ENST00000373818.4	GSN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	gelsolin
chr12_+_101988627 Show fit	12.38	ENST00000547405.1 ENST00000452455.2 ENST00000441232.1 ENST00000360610.2 ENST00000392934.3 ENST00000547509.1 ENST00000361685.2 ENST00000549145.1 ENST00000553190.1	MYBPC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin binding protein C, slow type
chr7_+_86273700 Show fit	12.18	ENST00000546348.1	GRM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, metabotropic 3
chr6_+_19837592 Show fit	12.07	ENST00000378700.3	ID4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr13_-_80915059 Show fit	11.98	ENST00000377104.3	SPRY2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sprouty homolog 2 (Drosophila)
chr2_-_68384603 Show fit	11.97	ENST00000406245.2 ENST00000409164.1 ENST00000295121.6	WDR92 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 92
chr16_-_1020954 Show fit	11.89	ENST00000543238.1 ENST00000539379.1 ENST00000399843.2 ENST00000262301.11	LMF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lipase maturation factor 1
chr1_+_156589051 Show fit	11.81	ENST00000255039.1	HAPLN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hyaluronan and proteoglycan link protein 2
chr7_-_31380502 Show fit	11.77	ENST00000297142.3	NEUROD6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neuronal differentiation 6
chr13_-_53422640 Show fit	11.71	ENST00000338862.4 ENST00000377942.3	PCDH8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin 8
chr4_-_46911223 Show fit	11.69	ENST00000396533.1	COX7B2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome c oxidase subunit VIIb2
chr4_+_71587669 Show fit	11.42	ENST00000381006.3 ENST00000226328.4	RUFY3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RUN and FYVE domain containing 3
chr19_+_35783047 Show fit	11.39	ENST00000595791.1 ENST00000597035.1 ENST00000537831.2	MAG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin associated glycoprotein
chr5_-_11588907 Show fit	11.21	ENST00000513598.1 ENST00000503622.1	CTNND2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	catenin (cadherin-associated protein), delta 2
chr20_-_62130474 Show fit	11.09	ENST00000217182.3	EEF1A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation elongation factor 1 alpha 2
chr1_+_151043070 Show fit	11.05	ENST00000368918.3 ENST00000368917.1	GABPB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GA binding protein transcription factor, beta subunit 2
chr10_+_18629628 Show fit	11.04	ENST00000377329.4	CACNB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium channel, voltage-dependent, beta 2 subunit
chr2_-_55277436 Show fit	10.99	ENST00000354474.6	RTN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	reticulon 4
chr20_-_52687059 Show fit	10.87	ENST00000371435.2 ENST00000395961.3	BCAS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	breast carcinoma amplified sequence 1
chr6_-_167276033 Show fit	10.67	ENST00000503859.1 ENST00000506565.1	RPS6KA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr16_+_29911864 Show fit	10.66	ENST00000308748.5	ASPHD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aspartate beta-hydroxylase domain containing 1
chr11_-_132813566 Show fit	10.65	ENST00000331898.7	OPCML Links Ensembl NCBI GeneCards UniProt NextProt Show fit	opioid binding protein/cell adhesion molecule-like
chr16_+_66914264 Show fit	10.64	ENST00000311765.2 ENST00000568869.1 ENST00000561704.1 ENST00000568398.1 ENST00000566776.1	PDP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pyruvate dehyrogenase phosphatase catalytic subunit 2
chr16_+_7382745 Show fit	10.64	ENST00000436368.2 ENST00000311745.5 ENST00000355637.4 ENST00000340209.4	RBFOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_-_50574856 Show fit	10.61	ENST00000342183.5	NRXN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neurexin 1
chrX_+_102631248 Show fit	10.57	ENST00000361298.4 ENST00000372645.3 ENST00000372635.1	NGFRAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nerve growth factor receptor (TNFRSF16) associated protein 1
chr5_-_20575959 Show fit	10.56	ENST00000507958.1	CDH18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cadherin 18, type 2
chr7_-_137028498 Show fit	10.56	ENST00000393083.2	PTN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pleiotrophin
chr16_+_31085714 Show fit	10.53	ENST00000300850.5 ENST00000564189.1 ENST00000428260.1	ZNF646 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 646
chr17_+_26684604 Show fit	10.52	ENST00000292114.3 ENST00000509083.1	TMEM199 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 199
chr15_-_90892669 Show fit	10.51	ENST00000412799.2	GABARAPL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GABA(A) receptors associated protein like 3, pseudogene
chr1_+_154193325 Show fit	10.48	ENST00000428931.1 ENST00000441890.1 ENST00000271877.7 ENST00000412596.1 ENST00000368504.1 ENST00000437652.1	UBAP2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin associated protein 2-like
chr6_+_31982539 Show fit	10.42	ENST00000435363.2 ENST00000425700.2	C4B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 4B (Chido blood group)
chr15_-_88799948 Show fit	10.41	ENST00000394480.2	NTRK3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neurotrophic tyrosine kinase, receptor, type 3
chr12_+_6930813 Show fit	10.38	ENST00000428545.2	GPR162 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 162
chr18_+_29171689 Show fit	10.37	ENST00000237014.3	TTR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transthyretin
chr11_-_115630900 Show fit	10.33	ENST00000537070.1 ENST00000499809.1 ENST00000514294.2 ENST00000535683.1	LINC00900 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 900
chr2_-_55277512 Show fit	10.29	ENST00000402434.2	RTN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	reticulon 4
chrX_-_34675391 Show fit	10.27	ENST00000275954.3	TMEM47 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 47
chr7_-_143059780 Show fit	10.23	ENST00000409578.1 ENST00000409346.1	FAM131B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 131, member B
chr10_-_81205373 Show fit	10.18	ENST00000372336.3	ZCCHC24 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, CCHC domain containing 24
chr6_+_126240442 Show fit	10.17	ENST00000448104.1 ENST00000438495.1 ENST00000444128.1	NCOA7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor coactivator 7
chr7_+_129251531 Show fit	10.16	ENST00000393232.1 ENST00000353868.4 ENST00000539636.1 ENST00000454688.1 ENST00000223190.4 ENST00000311967.2	NRF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear respiratory factor 1
chr1_+_233749739 Show fit	10.02	ENST00000366621.3	KCNK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium channel, subfamily K, member 1
chr8_+_21916680 Show fit	9.96	ENST00000358242.3 ENST00000415253.1	DMTN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dematin actin binding protein
chr6_+_123100620 Show fit	9.96	ENST00000368444.3	FABP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid binding protein 7, brain
chr5_-_24645078 Show fit	9.86	ENST00000264463.4	CDH10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cadherin 10, type 2 (T2-cadherin)
chr8_+_21916710 Show fit	9.82	ENST00000523266.1 ENST00000519907.1	DMTN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dematin actin binding protein
chr2_-_69870835 Show fit	9.79	ENST00000409085.4 ENST00000406297.3	AAK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	AP2 associated kinase 1
chr16_-_1020849 Show fit	9.74	ENST00000568897.1	LMF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lipase maturation factor 1
chr4_+_24797085 Show fit	9.73	ENST00000382120.3	SOD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	superoxide dismutase 3, extracellular
chr6_-_110501200 Show fit	9.71	ENST00000392586.1 ENST00000419252.1 ENST00000392589.1 ENST00000392588.1 ENST00000359451.2	WASF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WAS protein family, member 1
chr10_-_73848764 Show fit	9.66	ENST00000317376.4 ENST00000412663.1	SPOCK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_-_143059845 Show fit	9.64	ENST00000443739.2	FAM131B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 131, member B
chr5_-_11589131 Show fit	9.61	ENST00000511377.1	CTNND2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	catenin (cadherin-associated protein), delta 2
chr3_-_194991876 Show fit	9.54	ENST00000310380.6	XXYLT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	xyloside xylosyltransferase 1
chr12_+_113376249 Show fit	9.50	ENST00000551007.1 ENST00000548514.1	OAS3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	2'-5'-oligoadenylate synthetase 3, 100kDa
chr10_-_73848086 Show fit	9.50	ENST00000536168.1	SPOCK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr2_+_210517895 Show fit	9.37	ENST00000447185.1	MAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule-associated protein 2
chr19_-_10333842 Show fit	9.34	ENST00000317726.4	CTD-2369P2.2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CTD-2369P2.2
chr12_+_101988774 Show fit	9.34	ENST00000545503.2 ENST00000536007.1 ENST00000541119.1 ENST00000361466.2 ENST00000551300.1 ENST00000550270.1	MYBPC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin binding protein C, slow type
chr3_-_9291063 Show fit	9.27	ENST00000383836.3	SRGAP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SLIT-ROBO Rho GTPase activating protein 3
chr2_-_69870747 Show fit	9.25	ENST00000409068.1	AAK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	AP2 associated kinase 1
chr17_-_36956155 Show fit	9.23	ENST00000269554.3	PIP4K2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr6_-_116601044 Show fit	9.22	ENST00000368608.3	TSPYL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TSPY-like 1
chr2_+_45168875 Show fit	9.21	ENST00000260653.3	SIX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SIX homeobox 3
chr2_-_241737128 Show fit	9.14	ENST00000404283.3	KIF1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kinesin family member 1A
chr22_-_36236623 Show fit	9.12	ENST00000405409.2	RBFOX2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 2
chr11_-_66496430 Show fit	9.07	ENST00000533211.1	SPTBN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spectrin, beta, non-erythrocytic 2
chr11_+_131240373 Show fit	8.99	ENST00000374791.3 ENST00000436745.1	NTM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neurotrimin
chr6_+_43543864 Show fit	8.90	ENST00000372236.4 ENST00000535400.1	POLH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (DNA directed), eta
chr6_-_110500905 Show fit	8.79	ENST00000392587.2	WASF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WAS protein family, member 1
chr18_-_52989525 Show fit	8.78	ENST00000457482.3	TCF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor 4
chr1_-_72748417 Show fit	8.78	ENST00000357731.5	NEGR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neuronal growth regulator 1
chr5_+_140345820 Show fit	8.76	ENST00000289269.5	PCDHAC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin alpha subfamily C, 2
chr11_-_5255696 Show fit	8.68	ENST00000292901.3 ENST00000417377.1	HBD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hemoglobin, delta
chr17_+_57232690 Show fit	8.66	ENST00000262293.4	PRR11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proline rich 11
chr12_+_121088291 Show fit	8.54	ENST00000351200.2	CABP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium binding protein 1
chr2_+_173686303 Show fit	8.49	ENST00000397087.3	RAPGEF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rap guanine nucleotide exchange factor (GEF) 4
chr3_-_47619623 Show fit	8.43	ENST00000456150.1	CSPG5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr1_+_17906970 Show fit	8.42	ENST00000375415.1	ARHGEF10L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_76092353 Show fit	8.42	ENST00000530460.1 ENST00000321844.4	RP11-111M22.2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Homo sapiens putative uncharacterized protein FLJ37770-like (LOC100506127), mRNA.
chr11_-_117166276 Show fit	8.37	ENST00000510630.1 ENST00000392937.6	BACE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	beta-site APP-cleaving enzyme 1
chr12_+_6930703 Show fit	8.36	ENST00000311268.3	GPR162 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 162
chrX_+_70316005 Show fit	8.36	ENST00000374259.3	FOXO4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	forkhead box O4
chr18_-_52969844 Show fit	8.34	ENST00000561831.3	TCF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor 4
chr5_-_146258291 Show fit	8.28	ENST00000394411.4 ENST00000453001.1	PPP2R2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2, regulatory subunit B, beta
chr19_-_51920952 Show fit	8.10	ENST00000356298.5 ENST00000339313.5 ENST00000529627.1 ENST00000439889.2 ENST00000353836.5 ENST00000432469.2	SIGLEC10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sialic acid binding Ig-like lectin 10
chr20_+_17207665 Show fit	8.08	ENST00000536609.1	PCSK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proprotein convertase subtilisin/kexin type 2
chr4_-_87028478 Show fit	8.04	ENST00000515400.1 ENST00000395157.3	MAPK10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase 10
chr5_+_112227311 Show fit	8.03	ENST00000391338.1	ZRSR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr2_-_122407007 Show fit	7.95	ENST00000263710.4 ENST00000455322.2 ENST00000397587.3 ENST00000541377.1	CLASP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytoplasmic linker associated protein 1

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.3	55.0	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
10.9	196.5	GO:0007021	tubulin complex assembly(GO:0007021)
10.9	108.7	GO:0016198	axon choice point recognition(GO:0016198)
8.4	25.1	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
7.9	23.7	GO:1904395	retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
7.6	121.1	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
7.3	44.1	GO:0052565	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
7.3	51.2	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
7.0	63.0	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
6.9	41.4	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
6.8	27.4	GO:0006542	glutamine biosynthetic process(GO:0006542)
5.7	17.1	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
5.3	26.7	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
5.2	20.7	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
4.5	53.7	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
4.5	26.7	GO:0038161	prolactin signaling pathway(GO:0038161)
4.4	13.3	GO:2000685	mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
4.3	47.2	GO:0006600	creatine metabolic process(GO:0006600)
4.0	56.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
4.0	12.0	GO:0060437	lung growth(GO:0060437)
3.9	94.6	GO:0032291	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
3.5	7.0	GO:0007497	posterior midgut development(GO:0007497)
3.5	10.4	GO:0048687	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
3.4	23.6	GO:0060075	regulation of resting membrane potential(GO:0060075)
3.3	19.8	GO:0070560	protein secretion by platelet(GO:0070560)
3.3	26.3	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
3.2	22.5	GO:0097688	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
3.2	6.4	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
3.1	15.4	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
3.1	24.6	GO:0033578	protein glycosylation in Golgi(GO:0033578)
3.1	9.2	GO:0021798	neuroblast differentiation(GO:0014016) forebrain dorsal/ventral pattern formation(GO:0021798) regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
2.9	14.6	GO:0099540	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
2.9	25.9	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
2.8	8.4	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
2.8	30.5	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
2.7	35.4	GO:0070327	thyroid hormone transport(GO:0070327)
2.7	10.6	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
2.6	2.6	GO:0010463	positive regulation of mesenchymal cell proliferation(GO:0002053) mesenchymal cell proliferation(GO:0010463) regulation of mesenchymal cell proliferation(GO:0010464)
2.5	5.0	GO:0072275	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.5	69.7	GO:0010669	epithelial structure maintenance(GO:0010669)
2.5	12.4	GO:1903906	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
2.4	9.6	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
2.4	64.5	GO:0007158	neuron cell-cell adhesion(GO:0007158)
2.4	11.8	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
2.4	16.5	GO:0006537	glutamate biosynthetic process(GO:0006537)
2.3	6.9	GO:0021888	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
2.3	6.8	GO:1905072	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
2.3	11.3	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
2.2	13.5	GO:1903278	regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
2.2	6.6	GO:0071557	histone H3-K27 demethylation(GO:0071557)
2.1	8.6	GO:0048807	ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
2.1	21.2	GO:0045329	carnitine biosynthetic process(GO:0045329)
2.1	10.5	GO:0007042	lysosomal lumen acidification(GO:0007042)
2.1	8.4	GO:0097676	histone H3-K36 dimethylation(GO:0097676)
2.0	15.7	GO:0015671	oxygen transport(GO:0015671)
1.9	36.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
1.9	28.7	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.9	5.7	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.9	5.6	GO:0070634	transepithelial ammonium transport(GO:0070634)
1.9	5.6	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
1.8	11.0	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.8	12.8	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
1.8	18.0	GO:0051610	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.8	10.8	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
1.8	5.3	GO:0001172	transcription, RNA-templated(GO:0001172)
1.7	10.5	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
1.7	7.0	GO:0007525	somatic muscle development(GO:0007525)
1.7	17.4	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
1.7	6.9	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
1.7	65.0	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
1.7	6.7	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
1.6	24.7	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
1.6	8.1	GO:0030070	insulin processing(GO:0030070)
1.6	14.3	GO:0016191	synaptic vesicle uncoating(GO:0016191)
1.6	11.0	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.6	3.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
1.5	1.5	GO:0003018	vascular process in circulatory system(GO:0003018) regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880)
1.5	4.5	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.5	4.5	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
1.5	4.4	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.5	1.5	GO:0010818	T cell chemotaxis(GO:0010818)
1.5	5.8	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
1.4	4.2	GO:0051097	negative regulation of helicase activity(GO:0051097)
1.4	12.5	GO:0032490	detection of molecule of bacterial origin(GO:0032490)
1.4	4.2	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
1.4	12.5	GO:0047484	regulation of response to osmotic stress(GO:0047484)
1.4	2.8	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
1.3	6.7	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
1.3	16.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
1.3	2.6	GO:0035962	response to interleukin-13(GO:0035962)
1.3	1.3	GO:0002763	positive regulation of myeloid leukocyte differentiation(GO:0002763)
1.2	6.2	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
1.2	2.5	GO:0015793	glycerol transport(GO:0015793)
1.2	8.5	GO:0042308	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590)
1.2	4.9	GO:0019086	late viral transcription(GO:0019086)
1.2	15.8	GO:0001867	complement activation, lectin pathway(GO:0001867)
1.2	4.8	GO:2000620	positive regulation of histone H4-K16 acetylation(GO:2000620)
1.2	38.0	GO:0008038	neuron recognition(GO:0008038)
1.2	7.1	GO:0052055	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.2	19.8	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
1.1	4.6	GO:0019805	quinolinate biosynthetic process(GO:0019805)
1.1	4.5	GO:1903597	negative regulation of gap junction assembly(GO:1903597)
1.1	4.5	GO:0006114	glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
1.1	11.3	GO:0060700	regulation of ribonuclease activity(GO:0060700)
1.1	14.4	GO:0006071	glycerol metabolic process(GO:0006071)
1.1	2.2	GO:0048867	stem cell fate determination(GO:0048867)
1.1	3.3	GO:0098528	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.1	2.1	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
1.1	4.2	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
1.0	36.6	GO:0007019	microtubule depolymerization(GO:0007019)
1.0	4.1	GO:0001519	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.0	9.2	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
1.0	8.0	GO:0007258	JUN phosphorylation(GO:0007258)
1.0	8.0	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
1.0	7.0	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
1.0	4.8	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
1.0	2.9	GO:0006014	D-ribose metabolic process(GO:0006014)
0.9	4.7	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.9	5.6	GO:0051012	microtubule sliding(GO:0051012)
0.9	5.6	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
0.9	3.7	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.9	2.8	GO:0015888	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.9	6.3	GO:0045007	depurination(GO:0045007)
0.9	3.5	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.9	2.6	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.9	3.5	GO:0006540	glutamate decarboxylation to succinate(GO:0006540)
0.9	2.6	GO:0021564	glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.9	6.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.9	3.4	GO:0035425	autocrine signaling(GO:0035425)
0.8	5.9	GO:0036438	maintenance of lens transparency(GO:0036438)
0.8	5.0	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.8	4.2	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.8	4.2	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.8	1.7	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.8	19.0	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.8	2.5	GO:2001303	lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.8	5.7	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.8	7.3	GO:0030322	stabilization of membrane potential(GO:0030322)
0.8	0.8	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.8	4.0	GO:0071918	urea transmembrane transport(GO:0071918)
0.8	3.9	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.8	5.5	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.8	10.2	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.8	3.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.8	4.5	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.7	6.0	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.7	2.2	GO:0071812	regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.7	3.6	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.7	10.1	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.7	5.7	GO:0071363	cellular response to growth factor stimulus(GO:0071363)
0.7	113.0	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.7	2.1	GO:1901994	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.7	3.5	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.7	4.9	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.7	6.2	GO:0008090	retrograde axonal transport(GO:0008090)
0.7	16.5	GO:0007628	adult walking behavior(GO:0007628)
0.7	2.7	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.7	9.4	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.7	3.3	GO:1904073	trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.7	9.3	GO:0060134	prepulse inhibition(GO:0060134)
0.7	3.3	GO:0036376	sodium ion export from cell(GO:0036376)
0.7	2.0	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.7	10.5	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.7	13.1	GO:0071420	cellular response to histamine(GO:0071420)
0.6	3.8	GO:0035799	ureter maturation(GO:0035799)
0.6	1.9	GO:0060042	retina morphogenesis in camera-type eye(GO:0060042)
0.6	7.4	GO:0035641	locomotory exploration behavior(GO:0035641)
0.6	1.2	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.6	3.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.6	1.8	GO:0045212	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.6	14.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.6	4.0	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6	3.4	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.6	2.3	GO:0015811	L-cystine transport(GO:0015811)
0.6	1.7	GO:0045726	regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.6	12.9	GO:0046688	response to copper ion(GO:0046688)
0.6	5.6	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.6	1.1	GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.5	10.7	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.5	4.2	GO:0002051	osteoblast fate commitment(GO:0002051)
0.5	1.6	GO:1901490	regulation of lymphangiogenesis(GO:1901490)
0.5	10.1	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.5	3.0	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.5	11.4	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.5	8.3	GO:0005513	detection of calcium ion(GO:0005513)
0.5	1.5	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.5	3.9	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.5	20.8	GO:0060997	dendritic spine morphogenesis(GO:0060997)
0.5	2.3	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.5	1.4	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4	10.7	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.4	2.7	GO:0042048	olfactory behavior(GO:0042048)
0.4	5.8	GO:0060736	prostate gland growth(GO:0060736)
0.4	8.4	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.4	2.2	GO:0021759	globus pallidus development(GO:0021759)
0.4	2.6	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.4	15.8	GO:0097484	dendrite extension(GO:0097484)
0.4	1.3	GO:0050720	interleukin-1 beta biosynthetic process(GO:0050720)
0.4	3.4	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.4	6.9	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.4	2.4	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4	1.2	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.4	5.5	GO:0045793	positive regulation of cell size(GO:0045793)
0.4	4.3	GO:0043586	tongue development(GO:0043586)
0.4	4.3	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.4	9.1	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.4	3.4	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4	0.7	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.4	2.6	GO:0006489	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.4	1.8	GO:0001555	oocyte growth(GO:0001555)
0.4	7.9	GO:0006833	water transport(GO:0006833)
0.4	1.8	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.4	9.2	GO:0010107	potassium ion import(GO:0010107)
0.4	4.9	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.3	17.5	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3	3.1	GO:0051552	flavone metabolic process(GO:0051552)
0.3	5.5	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.3	2.4	GO:0048681	negative regulation of myelination(GO:0031642) negative regulation of axon regeneration(GO:0048681)
0.3	2.4	GO:0006776	vitamin A metabolic process(GO:0006776)
0.3	4.7	GO:0030308	negative regulation of cell growth(GO:0030308)
0.3	1.6	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3	43.4	GO:0046718	viral entry into host cell(GO:0046718)
0.3	1.0	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.3	2.6	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3	3.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.3	2.7	GO:0031018	endocrine pancreas development(GO:0031018)
0.3	0.9	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.3	1.5	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.3	0.3	GO:0090325	regulation of locomotion involved in locomotory behavior(GO:0090325)
0.3	3.3	GO:0019216	regulation of lipid metabolic process(GO:0019216)
0.3	2.7	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.3	4.4	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.3	2.6	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3	0.9	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.3	1.9	GO:0072520	seminiferous tubule development(GO:0072520)
0.3	4.7	GO:0010927	cellular component assembly involved in morphogenesis(GO:0010927)
0.3	1.1	GO:0006203	dGTP catabolic process(GO:0006203)
0.3	2.7	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.3	1.1	GO:0003335	corneocyte development(GO:0003335)
0.3	6.2	GO:0001502	cartilage condensation(GO:0001502)
0.3	14.8	GO:0021954	central nervous system neuron development(GO:0021954)
0.3	0.8	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3	4.0	GO:0000338	protein deneddylation(GO:0000338)
0.3	5.6	GO:0048665	neuron fate specification(GO:0048665)
0.3	6.6	GO:0038084	vascular endothelial growth factor signaling pathway(GO:0038084)
0.3	4.8	GO:0044804	nucleophagy(GO:0044804)
0.3	1.6	GO:1903506	regulation of nucleic acid-templated transcription(GO:1903506) regulation of RNA biosynthetic process(GO:2001141)
0.3	0.5	GO:0018879	biphenyl metabolic process(GO:0018879)
0.3	3.4	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.3	5.1	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.3	4.3	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.3	1.0	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.3	4.0	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.3	0.8	GO:0051941	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.3	6.3	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2	35.0	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.2	1.0	GO:0052697	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2	2.2	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2	0.9	GO:0021590	cerebellum maturation(GO:0021590) cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699)
0.2	2.6	GO:0016576	histone dephosphorylation(GO:0016576)
0.2	2.3	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2	3.6	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.2	10.6	GO:0007050	cell cycle arrest(GO:0007050)
0.2	1.8	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.2	1.6	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.2	1.8	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.2	0.4	GO:0061743	motor learning(GO:0061743)
0.2	11.1	GO:0016266	O-glycan processing(GO:0016266)
0.2	5.0	GO:0006884	cell volume homeostasis(GO:0006884)
0.2	12.3	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2	2.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	5.8	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	3.6	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2	5.0	GO:0009083	branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.2	5.4	GO:1903779	regulation of cardiac conduction(GO:1903779)
0.2	0.8	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2	6.2	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.2	6.3	GO:0016486	peptide hormone processing(GO:0016486)
0.2	3.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.2	8.4	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.2	3.1	GO:0021542	dentate gyrus development(GO:0021542)
0.2	0.5	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.2	0.4	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.2	3.0	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2	12.9	GO:0006826	iron ion transport(GO:0006826)
0.2	3.1	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2	5.8	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.2	1.1	GO:0072592	oxygen metabolic process(GO:0072592)
0.2	8.5	GO:0007517	muscle organ development(GO:0007517)
0.2	0.6	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1	9.5	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1	4.1	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.1	4.2	GO:0008089	anterograde axonal transport(GO:0008089)
0.1	3.4	GO:0010762	regulation of fibroblast migration(GO:0010762)
0.1	1.2	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.1	0.8	GO:0003360	brainstem development(GO:0003360)
0.1	4.5	GO:0019433	triglyceride catabolic process(GO:0019433)
0.1	16.4	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1	3.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.4	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	3.3	GO:0014887	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1	1.2	GO:0035095	behavioral response to nicotine(GO:0035095)
0.1	1.8	GO:0051497	negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.1	0.3	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1	2.4	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1	4.1	GO:0005980	glycogen catabolic process(GO:0005980)
0.1	2.2	GO:0050919	negative chemotaxis(GO:0050919)
0.1	0.6	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.1	0.3	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	0.7	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1	0.3	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1	1.5	GO:0060732	regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1	0.4	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1	4.1	GO:0006458	'de novo' protein folding(GO:0006458)
0.1	0.7	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.1	0.2	GO:0005988	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1	2.6	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.1	3.9	GO:0051865	protein autoubiquitination(GO:0051865)
0.1	1.8	GO:0007340	acrosome reaction(GO:0007340)
0.1	1.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	2.5	GO:0003009	skeletal muscle contraction(GO:0003009)
0.1	1.2	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	1.1	GO:0043524	negative regulation of neuron apoptotic process(GO:0043524)
0.1	0.6	GO:0051775	response to redox state(GO:0051775)
0.1	0.3	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1	0.2	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1	0.3	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1	1.5	GO:0045773	positive regulation of axon extension(GO:0045773)
0.1	2.1	GO:0061512	protein localization to cilium(GO:0061512)
0.1	0.6	GO:0008544	epidermis development(GO:0008544)
0.0	4.9	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	0.7	GO:0048593	camera-type eye morphogenesis(GO:0048593)
0.0	1.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	1.3	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0	0.7	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	2.2	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.1	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0	1.3	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.6	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.0	0.4	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.9	GO:0046710	GDP metabolic process(GO:0046710)
0.0	0.7	GO:0003417	growth plate cartilage development(GO:0003417)
0.0	0.5	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	0.2	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	7.2	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.9	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.4	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.0	1.3	GO:0007422	peripheral nervous system development(GO:0007422)
0.0	0.5	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.2	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.3	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.1	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.7	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.1	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0042428	serotonin metabolic process(GO:0042428)
0.0	0.5	GO:0060711	labyrinthine layer development(GO:0060711)
0.0	0.4	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.7	GO:0032006	regulation of TOR signaling(GO:0032006)
0.0	0.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.5	108.8	GO:0032584	growth cone membrane(GO:0032584)
13.1	210.0	GO:0097512	cardiac myofibril(GO:0097512)
11.1	55.7	GO:0098843	postsynaptic endocytic zone(GO:0098843)
11.0	55.0	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
5.2	41.4	GO:0045179	apical cortex(GO:0045179)
4.7	14.0	GO:0097447	dendritic tree(GO:0097447)
4.4	26.4	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
4.1	81.9	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
3.8	26.7	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
3.8	11.4	GO:1990015	mesaxon(GO:0097453) ensheathing process(GO:1990015)
3.6	50.4	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
3.2	12.8	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
3.1	63.0	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
2.5	22.8	GO:0098839	postsynaptic density membrane(GO:0098839)
2.4	7.1	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
2.0	10.0	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
1.8	11.0	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
1.8	34.3	GO:0097386	glial cell projection(GO:0097386)
1.8	43.9	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
1.8	21.0	GO:0060077	inhibitory synapse(GO:0060077)
1.7	3.3	GO:0044308	axonal spine(GO:0044308)
1.6	8.0	GO:0089701	U2AF(GO:0089701)
1.6	6.2	GO:0031673	H zone(GO:0031673)
1.5	3.0	GO:0045298	tubulin complex(GO:0045298)
1.4	30.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
1.4	20.0	GO:0042583	chromaffin granule(GO:0042583)
1.3	12.5	GO:0031209	SCAR complex(GO:0031209)
1.2	13.3	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
1.1	11.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
1.1	214.0	GO:0030426	growth cone(GO:0030426)
1.0	5.0	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.9	20.8	GO:0032982	myosin filament(GO:0032982)
0.9	11.0	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.8	12.4	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.8	3.1	GO:0036449	microtubule minus-end(GO:0036449)
0.8	2.3	GO:0005873	plus-end kinesin complex(GO:0005873)
0.8	10.5	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.7	3.0	GO:0005797	Golgi medial cisterna(GO:0005797)
0.7	4.3	GO:0030893	meiotic cohesin complex(GO:0030893)
0.7	10.7	GO:0030478	actin cap(GO:0030478)
0.7	2.7	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.6	6.3	GO:0044297	cell body(GO:0044297)
0.6	8.7	GO:0005833	hemoglobin complex(GO:0005833)
0.6	1.8	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.6	5.4	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.6	3.6	GO:1990769	proximal neuron projection(GO:1990769)
0.6	4.2	GO:0070852	cell body fiber(GO:0070852)
0.6	40.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.6	12.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.6	10.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.5	4.8	GO:0071439	clathrin complex(GO:0071439)
0.5	2.7	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.5	2.5	GO:0005594	collagen type IX trimer(GO:0005594)
0.5	64.3	GO:0043204	perikaryon(GO:0043204)
0.5	8.9	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.5	4.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.5	7.7	GO:0045277	respiratory chain complex IV(GO:0045277)
0.4	4.0	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.4	2.2	GO:0035253	ciliary rootlet(GO:0035253)
0.4	2.6	GO:0070545	PeBoW complex(GO:0070545)
0.4	1.3	GO:0016013	syntrophin complex(GO:0016013)
0.4	14.0	GO:0060076	excitatory synapse(GO:0060076)
0.4	3.8	GO:0005579	membrane attack complex(GO:0005579)
0.4	29.3	GO:0042734	presynaptic membrane(GO:0042734)
0.4	91.1	GO:0043209	myelin sheath(GO:0043209)
0.4	5.3	GO:0000974	Prp19 complex(GO:0000974)
0.4	1.8	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.4	17.6	GO:0031594	neuromuscular junction(GO:0031594)
0.3	51.5	GO:0031225	anchored component of membrane(GO:0031225)
0.3	4.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.3	1.7	GO:0071438	invadopodium membrane(GO:0071438)
0.3	4.7	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.3	2.0	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.3	3.3	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.3	2.5	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3	10.8	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.3	5.3	GO:0005922	connexon complex(GO:0005922)
0.3	8.4	GO:0035861	site of double-strand break(GO:0035861)
0.3	11.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.3	3.5	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.3	6.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.3	8.4	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.3	4.8	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.3	9.9	GO:0000421	autophagosome membrane(GO:0000421)
0.3	2.6	GO:0005614	interstitial matrix(GO:0005614)
0.3	2.8	GO:0033268	node of Ranvier(GO:0033268)
0.2	1.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2	6.4	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2	4.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2	57.1	GO:0045211	postsynaptic membrane(GO:0045211)
0.2	19.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2	12.1	GO:0031904	endosome lumen(GO:0031904)
0.2	2.4	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2	19.0	GO:0005905	clathrin-coated pit(GO:0005905)
0.2	2.8	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.2	9.2	GO:0005776	autophagosome(GO:0005776)
0.2	1.9	GO:0001739	sex chromatin(GO:0001739)
0.2	6.8	GO:0016592	mediator complex(GO:0016592)
0.2	10.8	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.2	9.0	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2	10.8	GO:0005796	Golgi lumen(GO:0005796)
0.2	1.8	GO:0044666	MLL3/4 complex(GO:0044666)
0.2	4.0	GO:0008180	COP9 signalosome(GO:0008180)
0.1	6.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	5.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	7.7	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	1.5	GO:0016600	flotillin complex(GO:0016600)
0.1	3.5	GO:0002080	acrosomal membrane(GO:0002080)
0.1	2.5	GO:0005861	troponin complex(GO:0005861)
0.1	20.0	GO:0005875	microtubule associated complex(GO:0005875)
0.1	2.7	GO:0030315	T-tubule(GO:0030315)
0.1	3.6	GO:0005771	multivesicular body(GO:0005771)
0.1	6.7	GO:0005901	caveola(GO:0005901)
0.1	1.4	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	2.5	GO:0001533	cornified envelope(GO:0001533)
0.1	0.7	GO:0031931	TORC1 complex(GO:0031931)
0.1	5.4	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	1.8	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	2.5	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	0.8	GO:0005921	gap junction(GO:0005921)
0.1	1.5	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	6.7	GO:0005802	trans-Golgi network(GO:0005802)
0.1	0.8	GO:0034451	centriolar satellite(GO:0034451)
0.1	0.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.3	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	0.9	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.1	1.3	GO:0009925	basal plasma membrane(GO:0009925)
0.1	18.0	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	6.5	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0	2.4	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	2.7	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	2.2	GO:0098794	postsynapse(GO:0098794)
0.0	1.2	GO:0030057	desmosome(GO:0030057)
0.0	0.2	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	0.2	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	32.2	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	3.6	GO:0005814	centriole(GO:0005814)
0.0	2.9	GO:0045202	synapse(GO:0045202)
0.0	0.2	GO:0042629	mast cell granule(GO:0042629)
0.0	7.9	GO:0031252	cell leading edge(GO:0031252)
0.0	1.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.7	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.5	GO:0044439	microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0	0.6	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.5	GO:0097546	ciliary base(GO:0097546)
0.0	0.4	GO:0071564	npBAF complex(GO:0071564)
0.0	0.3	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.0	55.0	GO:0030348	syntaxin-3 binding(GO:0030348)
10.1	101.4	GO:0035727	lysophosphatidic acid binding(GO:0035727)
7.7	23.1	GO:0030350	iron-responsive element binding(GO:0030350)
7.6	83.4	GO:0030274	LIM domain binding(GO:0030274)
7.5	22.5	GO:0031811	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
6.8	27.4	GO:0004356	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
5.9	23.7	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
5.9	47.2	GO:0004111	creatine kinase activity(GO:0004111)
5.8	69.4	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
5.6	172.6	GO:0005212	structural constituent of eye lens(GO:0005212)
5.3	26.7	GO:0004925	prolactin receptor activity(GO:0004925)
5.3	21.2	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
4.9	14.6	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
4.7	18.8	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
4.4	13.3	GO:0035501	MH1 domain binding(GO:0035501)
4.4	13.3	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
4.3	52.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
4.1	65.5	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
3.3	26.7	GO:0050816	phosphothreonine binding(GO:0050816)
3.1	9.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
3.1	18.3	GO:0004522	ribonuclease A activity(GO:0004522)
2.9	14.6	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
2.8	8.4	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
2.8	11.0	GO:0043515	kinetochore binding(GO:0043515)
2.6	13.1	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
2.6	12.8	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
2.5	20.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
2.4	12.2	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
2.3	7.0	GO:0004962	endothelin receptor activity(GO:0004962)
2.3	29.9	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.3	29.4	GO:0097109	neuroligin family protein binding(GO:0097109)
2.2	6.6	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
2.1	27.3	GO:0031432	titin binding(GO:0031432)
2.0	8.0	GO:0030305	heparanase activity(GO:0030305)
2.0	41.4	GO:0043560	insulin receptor substrate binding(GO:0043560)
1.9	13.6	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
1.9	9.5	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
1.9	5.6	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
1.8	10.6	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.8	7.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.8	43.9	GO:0004383	guanylate cyclase activity(GO:0004383)
1.8	12.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.8	5.3	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
1.7	17.3	GO:0022841	potassium ion leak channel activity(GO:0022841)
1.7	5.0	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
1.7	21.7	GO:0005344	oxygen transporter activity(GO:0005344)
1.7	5.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
1.6	8.0	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
1.6	6.3	GO:0032406	MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
1.6	4.7	GO:0051373	FATZ binding(GO:0051373)
1.5	12.4	GO:0030172	troponin C binding(GO:0030172)
1.5	4.5	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.4	5.7	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
1.4	8.4	GO:0044547	DNA topoisomerase binding(GO:0044547)
1.4	36.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.4	11.0	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.3	6.7	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
1.3	8.0	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.3	5.3	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
1.3	10.4	GO:0005030	neurotrophin receptor activity(GO:0005030)
1.3	10.4	GO:0070324	thyroid hormone binding(GO:0070324)
1.3	10.3	GO:0004565	beta-galactosidase activity(GO:0004565)
1.2	2.5	GO:0015254	glycerol channel activity(GO:0015254)
1.2	24.5	GO:0051787	misfolded protein binding(GO:0051787)
1.2	30.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
1.2	26.7	GO:0002162	dystroglycan binding(GO:0002162)
1.2	10.7	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
1.1	3.4	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
1.1	9.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
1.1	11.3	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
1.1	3.4	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.1	6.7	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.1	3.3	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
1.1	9.7	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.1	14.0	GO:0030215	semaphorin receptor binding(GO:0030215)
1.1	7.5	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.1	4.3	GO:0004351	glutamate decarboxylase activity(GO:0004351)
1.0	4.1	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.0	7.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
1.0	5.0	GO:0004974	leukotriene receptor activity(GO:0004974)
1.0	16.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.9	2.8	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.9	5.5	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.9	11.4	GO:0033691	sialic acid binding(GO:0033691)
0.9	18.0	GO:0005112	Notch binding(GO:0005112)
0.9	8.6	GO:0009374	biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.8	15.6	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.8	2.5	GO:0047977	hepoxilin-epoxide hydrolase activity(GO:0047977)
0.8	2.4	GO:0005148	prolactin receptor binding(GO:0005148)
0.8	54.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.8	4.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.8	7.0	GO:0051425	PTB domain binding(GO:0051425)
0.8	10.6	GO:0003680	AT DNA binding(GO:0003680)
0.8	4.5	GO:0008240	tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241)
0.8	3.0	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.7	5.0	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.7	4.1	GO:0004447	iodide peroxidase activity(GO:0004447)
0.7	4.8	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.7	8.6	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.7	7.9	GO:0015250	water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.6	5.7	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.6	8.6	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.6	6.0	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.6	2.4	GO:0005502	11-cis retinal binding(GO:0005502)
0.6	57.9	GO:0001618	virus receptor activity(GO:0001618)
0.6	9.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.6	5.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.6	5.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.6	16.4	GO:0034061	DNA polymerase activity(GO:0034061)
0.5	4.4	GO:0097322	7SK snRNA binding(GO:0097322)
0.5	2.7	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.5	1.6	GO:0047783	steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.5	17.8	GO:0017091	AU-rich element binding(GO:0017091)
0.5	2.5	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.5	4.5	GO:0005000	vasopressin receptor activity(GO:0005000)
0.5	3.0	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.5	6.5	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.5	6.7	GO:0008179	adenylate cyclase binding(GO:0008179)
0.5	3.3	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.5	4.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.4	4.4	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.4	3.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4	5.4	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.4	2.5	GO:0005499	vitamin D binding(GO:0005499)
0.4	4.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.4	11.1	GO:0003746	translation elongation factor activity(GO:0003746)
0.4	4.5	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.4	10.6	GO:0030506	ankyrin binding(GO:0030506)
0.4	0.8	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.4	6.3	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.4	20.7	GO:0015485	cholesterol binding(GO:0015485)
0.4	3.0	GO:0038132	neuregulin binding(GO:0038132)
0.4	2.3	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.4	2.5	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.4	1.8	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.3	17.5	GO:0004984	olfactory receptor activity(GO:0004984)
0.3	3.8	GO:0016918	retinal binding(GO:0016918)
0.3	6.9	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3	5.4	GO:0017166	vinculin binding(GO:0017166)
0.3	2.7	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3	7.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.3	7.6	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.3	1.0	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.3	3.5	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.3	6.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.3	0.9	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.3	1.5	GO:0004994	somatostatin receptor activity(GO:0004994)
0.3	7.9	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3	15.4	GO:0048365	Rac GTPase binding(GO:0048365)
0.3	0.9	GO:0042289	MHC class II protein binding(GO:0042289)
0.3	6.6	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3	1.7	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.3	3.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.3	2.9	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3	10.5	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.3	2.9	GO:0070330	aromatase activity(GO:0070330)
0.3	4.4	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.3	6.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.3	1.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3	20.8	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3	3.0	GO:0045159	myosin II binding(GO:0045159)
0.3	2.8	GO:0043274	phospholipase binding(GO:0043274)
0.2	2.7	GO:0019215	intermediate filament binding(GO:0019215)
0.2	2.6	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2	4.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2	4.5	GO:0008066	glutamate receptor activity(GO:0008066)
0.2	23.5	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2	8.8	GO:0030552	cAMP binding(GO:0030552)
0.2	2.4	GO:0008430	selenium binding(GO:0008430)
0.2	1.1	GO:0034056	estrogen response element binding(GO:0034056)
0.2	1.3	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2	5.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.2	1.7	GO:0004000	adenosine deaminase activity(GO:0004000)
0.2	9.4	GO:0030507	spectrin binding(GO:0030507)
0.2	1.8	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.2	7.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	2.2	GO:0038191	neuropilin binding(GO:0038191)
0.2	3.0	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2	1.4	GO:0000146	microfilament motor activity(GO:0000146)
0.2	11.2	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2	3.6	GO:0016805	dipeptidase activity(GO:0016805)
0.2	3.6	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2	5.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.2	1.1	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.2	2.6	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2	139.1	GO:0005509	calcium ion binding(GO:0005509)
0.2	2.7	GO:0005243	gap junction channel activity(GO:0005243)
0.2	3.0	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.2	1.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	17.1	GO:0044325	ion channel binding(GO:0044325)
0.2	0.5	GO:0005174	CD40 receptor binding(GO:0005174)
0.2	1.6	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2	1.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.2	2.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.2	1.7	GO:0039706	co-receptor binding(GO:0039706)
0.1	4.1	GO:0001972	retinoic acid binding(GO:0001972)
0.1	10.7	GO:0051213	dioxygenase activity(GO:0051213)
0.1	0.8	GO:0032027	myosin light chain binding(GO:0032027)
0.1	1.8	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1	5.0	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1	12.4	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1	3.4	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	2.4	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	0.6	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	1.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.7	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1	19.6	GO:0051015	actin filament binding(GO:0051015)
0.1	2.2	GO:0001848	complement binding(GO:0001848)
0.1	2.8	GO:0017048	Rho GTPase binding(GO:0017048)
0.1	33.3	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.1	0.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	6.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.1	1.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	22.2	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.1	7.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	6.3	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.1	2.9	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.1	2.2	GO:0019894	kinesin binding(GO:0019894)
0.1	6.9	GO:0043130	ubiquitin binding(GO:0043130)
0.1	22.7	GO:0015631	tubulin binding(GO:0015631)
0.1	7.2	GO:0008565	protein transporter activity(GO:0008565)
0.1	5.6	GO:0008013	beta-catenin binding(GO:0008013)
0.1	5.3	GO:0051087	chaperone binding(GO:0051087)
0.1	0.5	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1	2.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	1.0	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	0.2	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
0.1	12.0	GO:0000287	magnesium ion binding(GO:0000287)
0.1	3.3	GO:0019902	phosphatase binding(GO:0019902)
0.1	6.2	GO:0005178	integrin binding(GO:0005178)
0.1	0.8	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1	1.2	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	0.9	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1	15.0	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.5	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467) fatty acid ligase activity(GO:0015645) decanoate--CoA ligase activity(GO:0102391)
0.0	1.0	GO:0005343	organic acid:sodium symporter activity(GO:0005343)
0.0	1.5	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.6	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	1.9	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	2.0	GO:0005506	iron ion binding(GO:0005506)
0.0	1.2	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	0.7	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.6	GO:0008301	DNA binding, bending(GO:0008301)
0.0	1.8	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	1.7	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	1.0	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	2.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	1.6	GO:0008146	sulfotransferase activity(GO:0008146)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.4	GO:0005109	frizzled binding(GO:0005109)
0.0	1.0	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.3	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.6	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	163.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
1.6	87.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
1.5	1.5	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
1.2	61.8	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
1.2	54.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.8	23.7	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.8	35.5	ST GA13 PATHWAY	G alpha 13 Pathway
0.7	61.1	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.7	7.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.7	30.3	PID MYC PATHWAY	C-MYC pathway
0.7	50.9	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.6	27.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.5	24.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.5	66.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.5	14.9	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.4	7.9	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.4	11.9	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.4	9.4	PID ARF 3PATHWAY	Arf1 pathway
0.4	7.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.4	19.8	PID ATR PATHWAY	ATR signaling pathway
0.4	27.3	PID LKB1 PATHWAY	LKB1 signaling events
0.4	5.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.4	10.6	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.3	20.7	PID RAC1 PATHWAY	RAC1 signaling pathway
0.3	3.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	14.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.3	14.0	PID ENDOTHELIN PATHWAY	Endothelins
0.2	1.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.2	50.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	2.9	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.2	3.4	PID RHOA PATHWAY	RhoA signaling pathway
0.2	2.6	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.2	4.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	3.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	8.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	13.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	5.7	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	2.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	3.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	3.0	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	1.8	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	9.0	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	3.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	3.5	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	24.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	4.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	1.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	3.0	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.1	0.8	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	3.5	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	1.9	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.5	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.8	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.5	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	57.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
2.8	66.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
2.5	17.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
1.7	41.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.7	44.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.6	28.7	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.6	17.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.4	77.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
1.0	26.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
1.0	31.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.9	29.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.9	48.1	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.9	15.6	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.8	17.9	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.8	8.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.8	87.7	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.8	37.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.7	12.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.7	10.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.7	31.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.7	6.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.7	18.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.6	14.1	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.6	10.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.5	17.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.5	12.2	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.5	20.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.5	9.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.4	7.0	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4	7.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.4	15.0	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.4	12.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.4	4.6	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.4	4.5	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.4	89.8	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.4	6.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3	1.0	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.3	4.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.3	16.2	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.3	5.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	12.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.3	6.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.3	5.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.3	6.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.3	8.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.3	7.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.3	8.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3	5.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	4.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.2	2.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.2	6.7	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.2	3.5	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.2	3.6	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.2	8.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.2	19.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.2	5.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.2	7.5	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2	14.9	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	4.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	4.0	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.2	3.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	4.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2	14.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	2.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.2	2.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	4.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	6.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	2.5	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.1	3.8	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.1	2.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	7.1	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.1	9.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	14.0	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	3.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.1	2.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	5.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	2.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	2.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	2.2	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1	2.9	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.1	2.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	0.6	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.1	1.9	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	8.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	1.1	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	1.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.8	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.3	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.4	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	2.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling