averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 45.9 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
4.7 | 37.2 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536) |
0.5 | 34.7 | GO:0010257 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
6.2 | 30.9 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
0.2 | 29.7 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
0.2 | 27.7 | GO:0031424 | keratinization(GO:0031424) |
0.6 | 26.2 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
1.9 | 24.7 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
1.5 | 24.4 | GO:0006527 | arginine catabolic process(GO:0006527) |
0.4 | 23.5 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 79.2 | GO:0005615 | extracellular space(GO:0005615) |
1.4 | 42.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.1 | 37.5 | GO:0010008 | endosome membrane(GO:0010008) |
5.2 | 30.9 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.1 | 30.9 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
1.2 | 30.0 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.6 | 27.2 | GO:0045095 | keratin filament(GO:0045095) |
0.3 | 27.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.8 | 26.4 | GO:0005859 | muscle myosin complex(GO:0005859) |
1.0 | 26.0 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 78.4 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.2 | 63.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.6 | 49.6 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.4 | 30.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
1.1 | 26.0 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
0.8 | 24.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
4.9 | 24.4 | GO:0016403 | dimethylargininase activity(GO:0016403) |
0.1 | 24.4 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.4 | 23.2 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
4.5 | 22.6 | GO:0019798 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 69.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
1.0 | 41.1 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
0.3 | 18.3 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
0.2 | 17.1 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.2 | 15.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.2 | 14.2 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.2 | 10.6 | PID IL23 PATHWAY | IL23-mediated signaling events |
0.2 | 10.3 | PID PLK1 PATHWAY | PLK1 signaling events |
0.2 | 8.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
0.2 | 7.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 60.5 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
1.5 | 42.0 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
1.1 | 38.6 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
1.1 | 26.0 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
0.3 | 25.9 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.9 | 24.7 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.3 | 23.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
1.0 | 22.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.2 | 21.6 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
1.2 | 20.7 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |