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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FLI1

Z-value: 2.16

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Transcription factors associated with FLI1

Gene Symbol Gene ID Gene Info
FLI1
ENSG00000151702.12 Fli-1 proto-oncogene, ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FLI1hg19_v2_chr11_+_128563652_128563689,
hg19_v2_chr11_+_128562372_128562397,
hg19_v2_chr11_+_128634589_128634685,
hg19_v2_chr11_+_128563948_128564003		0.661.9e-28Click!

Activity profile of FLI1 motif

Sorted Z-values of FLI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_71791849 58.79 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr5_-_130970723 55.41 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr11_+_71791693 53.72 ENST00000289488.2
ENST00000447974.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr3_-_128879875 48.54 ENST00000418265.1
ENST00000393292.3
ENST00000273541.8
ISY1-RAB43
ISY1
ISY1-RAB43 readthrough
ISY1 splicing factor homolog (S. cerevisiae)
chr19_+_33182823 38.33 ENST00000397061.3
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr22_-_17680472 35.47 ENST00000330232.4
CECR1
cat eye syndrome chromosome region, candidate 1
chr14_+_100842735 34.68 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WDR25
WD repeat domain 25
chr18_-_72265035 33.52 ENST00000585279.1
ENST00000580048.1
LINC00909
long intergenic non-protein coding RNA 909
chr19_+_56186557 32.04 ENST00000270460.6
EPN1
epsin 1
chr2_+_17935383 31.93 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1
GEN1 Holliday junction 5' flap endonuclease
chr17_-_5138099 31.27 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr4_-_46911248 29.83 ENST00000355591.3
ENST00000505102.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr3_-_121379739 29.47 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr18_+_74240610 29.21 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
LINC00908
long intergenic non-protein coding RNA 908
chr15_+_74833518 28.15 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr6_+_31553901 27.52 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
LST1
leukocyte specific transcript 1
chr12_-_6798616 26.88 ENST00000355772.4
ENST00000417772.3
ENST00000396801.3
ENST00000396799.2
ZNF384
zinc finger protein 384
chr12_-_6798523 26.79 ENST00000319770.3
ZNF384
zinc finger protein 384
chr19_+_58694396 26.18 ENST00000326804.4
ENST00000345813.3
ENST00000424679.2
ZNF274
zinc finger protein 274
chr12_-_6798410 25.54 ENST00000361959.3
ENST00000436774.2
ENST00000544482.1
ZNF384
zinc finger protein 384
chr6_+_111580508 25.12 ENST00000368847.4
KIAA1919
KIAA1919
chr1_+_10003486 24.27 ENST00000403197.1
ENST00000377205.1
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr6_+_31553978 23.93 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr1_-_52831796 23.55 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
CC2D1B
coiled-coil and C2 domain containing 1B
chr2_-_24583583 23.31 ENST00000355123.4
ITSN2
intersectin 2
chr3_-_15469006 23.27 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
METTL6
methyltransferase like 6
chr3_-_195310802 23.00 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr13_-_44453826 22.70 ENST00000444614.3
CCDC122
coiled-coil domain containing 122
chr6_-_33239712 22.49 ENST00000436044.2
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr12_+_130554803 22.43 ENST00000535487.1
RP11-474D1.2
RP11-474D1.2
chr19_+_56186606 22.15 ENST00000085079.7
EPN1
epsin 1
chr21_-_46340770 21.82 ENST00000397854.3
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr21_-_46340884 21.57 ENST00000302347.5
ENST00000517819.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr22_-_38245304 21.17 ENST00000609454.1
ANKRD54
ankyrin repeat domain 54
chr14_+_23299088 21.13 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr11_-_64512803 20.42 ENST00000377489.1
ENST00000354024.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr15_+_81589254 20.33 ENST00000394652.2
IL16
interleukin 16
chr11_+_2421718 20.17 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4
tumor suppressing subtransferable candidate 4
chr16_-_28937027 20.10 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr11_-_64512273 19.85 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_+_4843679 19.85 ENST00000576229.1
RNF167
ring finger protein 167
chrX_+_128913906 19.78 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr10_-_72362515 19.57 ENST00000373209.2
ENST00000441259.1
PRF1
perforin 1 (pore forming protein)
chr18_-_74844727 19.44 ENST00000355994.2
ENST00000579129.1
MBP
myelin basic protein
chr11_-_71791435 19.41 ENST00000351960.6
ENST00000541719.1
ENST00000535111.1
NUMA1
nuclear mitotic apparatus protein 1
chr5_+_137801160 19.38 ENST00000239938.4
EGR1
early growth response 1
chr3_-_18480260 19.30 ENST00000454909.2
SATB1
SATB homeobox 1
chr11_-_71791518 19.21 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
NUMA1
nuclear mitotic apparatus protein 1
chr3_+_15468862 19.20 ENST00000396842.2
EAF1
ELL associated factor 1
chrX_-_102348017 19.09 ENST00000425644.1
ENST00000395065.3
ENST00000425463.2
NXF3
nuclear RNA export factor 3
chr11_-_71791726 18.91 ENST00000393695.3
NUMA1
nuclear mitotic apparatus protein 1
chr17_+_4843654 18.83 ENST00000575111.1
RNF167
ring finger protein 167
chr11_-_62389449 18.44 ENST00000534026.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr14_+_69865401 18.22 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9
solute carrier family 39, member 9
chr5_-_118324200 18.08 ENST00000515439.3
ENST00000510708.1
DTWD2
DTW domain containing 2
chr22_+_23165153 17.79 ENST00000390317.2
IGLV2-8
immunoglobulin lambda variable 2-8
chr3_+_57541975 17.74 ENST00000487257.1
ENST00000311180.8
PDE12
phosphodiesterase 12
chr15_+_71185148 17.74 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr11_-_61129335 17.71 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
CYB561A3
cytochrome b561 family, member A3
chrY_+_22918021 17.64 ENST00000288666.5
RPS4Y2
ribosomal protein S4, Y-linked 2
chr16_-_4466622 17.59 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
CORO7
coronin 7
chr16_+_27325202 17.44 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
IL4R
interleukin 4 receptor
chr6_-_33267101 17.42 ENST00000497454.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr18_-_47807829 17.29 ENST00000585672.1
ENST00000457839.2
ENST00000353909.3
ENST00000339998.6
ENST00000398493.1
MBD1
methyl-CpG binding domain protein 1
chr17_+_4843413 17.22 ENST00000572430.1
ENST00000262482.6
RNF167
ring finger protein 167
chr15_+_71184931 17.04 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr10_+_75545391 16.84 ENST00000604524.1
ENST00000605216.1
ENST00000398706.2
ZSWIM8
zinc finger, SWIM-type containing 8
chr19_+_3178736 16.73 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr19_+_47759716 16.64 ENST00000221922.6
CCDC9
coiled-coil domain containing 9
chr11_+_1874200 16.48 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr4_+_76439665 16.45 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6
THAP domain containing 6
chr1_+_153330322 16.43 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr2_-_24583314 16.29 ENST00000443927.1
ENST00000406921.3
ENST00000412011.1
ITSN2
intersectin 2
chr8_-_42397037 16.21 ENST00000342228.3
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr12_-_123215306 16.14 ENST00000356987.2
ENST00000436083.2
HCAR1
hydroxycarboxylic acid receptor 1
chr8_+_144373550 15.99 ENST00000330143.3
ENST00000521537.1
ENST00000518432.1
ENST00000520333.1
ZNF696
zinc finger protein 696
chr4_-_492891 15.90 ENST00000338977.5
ENST00000511833.2
ZNF721
zinc finger protein 721
chr19_-_58400148 15.80 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
ZNF814
zinc finger protein 814
chr18_-_47808050 15.77 ENST00000590208.1
MBD1
methyl-CpG binding domain protein 1
chr8_-_56685859 15.76 ENST00000523423.1
ENST00000523073.1
ENST00000519784.1
ENST00000434581.2
ENST00000519780.1
ENST00000521229.1
ENST00000522576.1
ENST00000523180.1
ENST00000522090.1
TMEM68
transmembrane protein 68
chr19_-_56632592 15.68 ENST00000587279.1
ENST00000270459.3
ZNF787
zinc finger protein 787
chr1_+_1260147 15.61 ENST00000343938.4
GLTPD1
glycolipid transfer protein domain containing 1
chr2_+_103035102 15.54 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr22_+_17565841 15.51 ENST00000319363.6
IL17RA
interleukin 17 receptor A
chr5_+_67584174 15.47 ENST00000320694.8
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr8_-_56685966 15.40 ENST00000334667.2
TMEM68
transmembrane protein 68
chr12_+_66218212 15.20 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
HMGA2
high mobility group AT-hook 2
chr12_+_53773944 15.05 ENST00000551969.1
ENST00000327443.4
SP1
Sp1 transcription factor
chr4_-_926069 15.04 ENST00000314167.4
ENST00000502656.1
GAK
cyclin G associated kinase
chr5_-_42811986 14.89 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr7_+_102004322 14.81 ENST00000496391.1
PRKRIP1
PRKR interacting protein 1 (IL11 inducible)
chr19_-_58400372 14.75 ENST00000597832.1
ENST00000435989.2
ZNF814
zinc finger protein 814
chr14_+_88471468 14.71 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chrX_-_40594755 14.70 ENST00000324817.1
MED14
mediator complex subunit 14
chrY_+_2709906 14.64 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr20_+_49575342 14.55 ENST00000244051.1
MOCS3
molybdenum cofactor synthesis 3
chr20_-_4795747 14.52 ENST00000379376.2
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr11_-_67205538 14.51 ENST00000326294.3
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr3_-_101232019 14.50 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr9_+_37753795 14.45 ENST00000377753.2
ENST00000537911.1
ENST00000377754.2
ENST00000297994.3
TRMT10B
tRNA methyltransferase 10 homolog B (S. cerevisiae)
chr10_+_75545329 14.41 ENST00000604729.1
ENST00000603114.1
ZSWIM8
zinc finger, SWIM-type containing 8
chr14_-_81687197 14.41 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr5_+_80597419 14.40 ENST00000254037.2
ENST00000407610.3
ENST00000380199.5
ZCCHC9
zinc finger, CCHC domain containing 9
chr4_-_165898768 14.31 ENST00000329314.5
TRIM61
tripartite motif containing 61
chr14_-_81687575 14.25 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr5_+_130506475 14.21 ENST00000379380.4
LYRM7
LYR motif containing 7
chr1_-_160001737 13.90 ENST00000368090.2
PIGM
phosphatidylinositol glycan anchor biosynthesis, class M
chr4_-_46911223 13.86 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr8_-_125486755 13.83 ENST00000499418.2
ENST00000530778.1
RNF139-AS1
RNF139 antisense RNA 1 (head to head)
chr19_+_42381173 13.79 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr11_-_62457371 13.77 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr6_+_83903061 13.76 ENST00000369724.4
ENST00000539997.1
RWDD2A
RWD domain containing 2A
chr4_+_2814011 13.66 ENST00000502260.1
ENST00000435136.2
SH3BP2
SH3-domain binding protein 2
chr6_-_33239612 13.60 ENST00000482399.1
ENST00000445902.2
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr21_-_38639601 13.56 ENST00000539844.1
ENST00000476950.1
ENST00000399001.1
DSCR3
Down syndrome critical region gene 3
chr2_+_113342163 13.54 ENST00000409719.1
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr19_+_58095501 13.54 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
ZIK1
zinc finger protein interacting with K protein 1
chr18_-_6414884 13.53 ENST00000317931.7
ENST00000284898.6
ENST00000400104.3
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr10_+_127408110 13.40 ENST00000356792.4
C10orf137
erythroid differentiation regulatory factor 1
chr8_-_21771214 13.39 ENST00000276420.4
DOK2
docking protein 2, 56kDa
chr20_-_44993012 13.30 ENST00000372229.1
ENST00000372230.5
ENST00000543605.1
ENST00000243896.2
ENST00000317734.8
SLC35C2
solute carrier family 35 (GDP-fucose transporter), member C2
chr2_-_208489707 13.28 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
METTL21A
methyltransferase like 21A
chr4_+_2813946 13.24 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr8_+_9046503 13.23 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr17_-_62097927 13.22 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
ICAM2
intercellular adhesion molecule 2
chr1_+_24882560 13.21 ENST00000374392.2
NCMAP
noncompact myelin associated protein
chr3_-_58563094 13.07 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr1_+_32716840 13.05 ENST00000336890.5
LCK
lymphocyte-specific protein tyrosine kinase
chr20_+_42839600 13.00 ENST00000439943.1
ENST00000437730.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr19_+_1077393 12.99 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr14_+_35515598 12.89 ENST00000280987.4
FAM177A1
family with sequence similarity 177, member A1
chr2_+_242641442 12.87 ENST00000313552.6
ENST00000406941.1
ING5
inhibitor of growth family, member 5
chr1_+_1510337 12.84 ENST00000366221.2
AL645728.1
Uncharacterized protein
chr6_-_112115074 12.78 ENST00000368667.2
FYN
FYN oncogene related to SRC, FGR, YES
chr1_-_113392399 12.75 ENST00000449572.2
ENST00000433505.1
RP11-426L16.8
RP11-426L16.8
chr6_-_33168391 12.66 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr11_+_46722368 12.62 ENST00000311764.2
ZNF408
zinc finger protein 408
chr3_-_39321512 12.60 ENST00000399220.2
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr9_-_86571628 12.58 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr1_+_209929494 12.54 ENST00000367026.3
TRAF3IP3
TRAF3 interacting protein 3
chr20_-_34638841 12.51 ENST00000565493.1
LINC00657
long intergenic non-protein coding RNA 657
chr12_-_105629852 12.48 ENST00000551662.1
ENST00000553097.1
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr7_+_150130742 12.45 ENST00000477392.1
ENST00000486954.1
LINC00996
long intergenic non-protein coding RNA 996
chr11_+_5710919 12.43 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr19_+_44455368 12.36 ENST00000591168.1
ENST00000587682.1
ENST00000251269.5
ZNF221
zinc finger protein 221
chr19_+_39881951 12.33 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr12_+_94071341 12.33 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_+_209929377 12.27 ENST00000400959.3
ENST00000367025.3
TRAF3IP3
TRAF3 interacting protein 3
chr11_+_118175596 12.26 ENST00000528600.1
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr12_+_9102632 12.21 ENST00000539240.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr11_-_64510409 12.21 ENST00000394429.1
ENST00000394428.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr9_+_123970052 12.08 ENST00000373823.3
GSN
gelsolin
chr21_-_38639813 12.08 ENST00000309117.6
ENST00000398998.1
DSCR3
Down syndrome critical region gene 3
chr21_+_44073916 12.00 ENST00000349112.3
ENST00000398224.3
PDE9A
phosphodiesterase 9A
chrX_-_70331298 11.99 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
IL2RG
interleukin 2 receptor, gamma
chr7_+_86781677 11.94 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
DMTF1
cyclin D binding myb-like transcription factor 1
chr1_-_2323140 11.94 ENST00000378531.3
ENST00000378529.3
MORN1
MORN repeat containing 1
chr11_-_417308 11.93 ENST00000397632.3
ENST00000382520.2
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr2_-_175351744 11.92 ENST00000295500.4
ENST00000392552.2
ENST00000392551.2
GPR155
G protein-coupled receptor 155
chr20_+_42839722 11.87 ENST00000442383.1
ENST00000435163.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr9_-_132404374 11.84 ENST00000277459.4
ENST00000450050.2
ENST00000277458.4
ASB6
ankyrin repeat and SOCS box containing 6
chr7_+_86781847 11.84 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
DMTF1
cyclin D binding myb-like transcription factor 1
chr7_-_150020578 11.83 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr10_-_27444143 11.82 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chrY_+_2709527 11.81 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr22_-_50312052 11.71 ENST00000330817.6
ALG12
ALG12, alpha-1,6-mannosyltransferase
chr1_+_32716857 11.68 ENST00000482949.1
ENST00000495610.2
LCK
lymphocyte-specific protein tyrosine kinase
chr9_-_91793675 11.67 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr20_-_48532019 11.67 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr16_+_1756162 11.66 ENST00000250894.4
ENST00000356010.5
MAPK8IP3
mitogen-activated protein kinase 8 interacting protein 3
chr4_+_153701081 11.64 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1
ADP-ribosylation factor interacting protein 1
chr1_+_209941827 11.63 ENST00000367023.1
TRAF3IP3
TRAF3 interacting protein 3
chr2_-_37193606 11.63 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr19_+_5681011 11.58 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr14_+_102027688 11.56 ENST00000510508.4
ENST00000359323.3
DIO3
deiodinase, iodothyronine, type III
chr9_-_95432536 11.55 ENST00000287996.3
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr19_-_36822595 11.54 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
LINC00665
long intergenic non-protein coding RNA 665
chr16_+_20817761 11.51 ENST00000568046.1
ENST00000261377.6
AC004381.6
Putative RNA exonuclease NEF-sp
chr11_-_407103 11.50 ENST00000526395.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr19_+_52901094 11.47 ENST00000391788.2
ENST00000436397.1
ENST00000391787.2
ENST00000360465.3
ENST00000494167.2
ENST00000493272.1
ZNF528
zinc finger protein 528
chr16_+_30483962 11.43 ENST00000356798.6
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr19_-_50316517 11.38 ENST00000313777.4
ENST00000445575.2
FUZ
fuzzy planar cell polarity protein
chr10_+_70847852 11.34 ENST00000242465.3
SRGN
serglycin
chr22_-_37545972 11.33 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr7_+_150020363 11.29 ENST00000359623.4
ENST00000493307.1
LRRC61
leucine rich repeat containing 61
chr19_-_50316489 11.25 ENST00000533418.1
FUZ
fuzzy planar cell polarity protein
chr19_+_18263928 11.19 ENST00000222254.8
PIK3R2
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr11_-_417388 11.13 ENST00000332725.3
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr1_-_157108266 11.11 ENST00000326786.4
ETV3
ets variant 3
chr1_-_36235559 11.09 ENST00000251195.5
CLSPN
claspin
chr1_-_160681593 11.02 ENST00000368045.3
ENST00000368046.3
CD48
CD48 molecule
chr1_-_200638964 11.02 ENST00000367348.3
ENST00000447706.2
ENST00000331314.6
DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr6_+_126240442 11.00 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr11_-_46722117 11.00 ENST00000311956.4
ARHGAP1
Rho GTPase activating protein 1
chr16_-_89556942 11.00 ENST00000301030.4
ANKRD11
ankyrin repeat domain 11
chr16_+_28996114 11.00 ENST00000395461.3
LAT
linker for activation of T cells
chr19_-_12595586 10.98 ENST00000397732.3
ZNF709
zinc finger protein 709
chr1_+_204485503 10.97 ENST00000367182.3
ENST00000507825.2
MDM4
Mdm4 p53 binding protein homolog (mouse)
chr1_+_36789335 10.97 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr5_-_443239 10.97 ENST00000408966.2
C5orf55
chromosome 5 open reading frame 55

Network of associatons between targets according to the STRING database.

First level regulatory network of FLI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
19.2 57.5 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
12.1 48.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
12.0 36.1 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
10.6 31.9 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
8.5 17.0 GO:0016574 histone ubiquitination(GO:0016574)
8.5 25.4 GO:1905224 clathrin-coated pit assembly(GO:1905224)
8.2 32.8 GO:2000314 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
6.7 20.1 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
6.2 18.5 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
6.2 18.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
6.1 18.2 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
6.0 114.7 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
5.5 16.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
5.4 16.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
5.4 26.8 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
4.9 34.6 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
4.9 14.6 GO:0018307 enzyme active site formation(GO:0018307)
4.7 23.6 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
4.6 23.0 GO:2000402 negative regulation of lipoprotein oxidation(GO:0034443) negative regulation of lymphocyte migration(GO:2000402)
4.4 13.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
4.4 22.0 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
4.2 12.6 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
4.2 25.0 GO:0060613 fat pad development(GO:0060613)
4.0 16.2 GO:0044375 regulation of peroxisome size(GO:0044375)
4.0 16.0 GO:0032053 ciliary basal body organization(GO:0032053)
3.9 15.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
3.8 11.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
3.4 10.3 GO:1901899 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
3.4 10.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
3.3 23.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
3.3 10.0 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
3.3 3.3 GO:1900027 regulation of ruffle assembly(GO:1900027)
3.2 13.0 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
3.2 50.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
3.1 9.4 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
3.1 12.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
3.1 9.3 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
3.0 9.0 GO:0070105 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
2.9 23.0 GO:0007506 gonadal mesoderm development(GO:0007506)
2.8 5.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
2.8 16.7 GO:0098535 de novo centriole assembly(GO:0098535)
2.7 2.7 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
2.7 10.9 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
2.7 10.9 GO:0071461 cellular response to redox state(GO:0071461)
2.7 24.3 GO:0006531 aspartate metabolic process(GO:0006531)
2.7 8.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
2.7 8.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
2.7 8.0 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
2.7 8.0 GO:0008355 olfactory learning(GO:0008355)
2.7 23.9 GO:0036066 protein O-linked fucosylation(GO:0036066)
2.6 42.2 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
2.6 7.9 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
2.6 10.5 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
2.6 5.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
2.6 7.8 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
2.6 10.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
2.6 5.1 GO:0071284 cellular response to lead ion(GO:0071284)
2.5 12.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
2.5 15.1 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
2.5 5.0 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
2.5 5.0 GO:0001101 response to acid chemical(GO:0001101)
2.5 7.4 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
2.5 7.4 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
2.4 12.1 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
2.4 9.6 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
2.4 7.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
2.3 37.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
2.3 9.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
2.3 20.4 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
2.3 29.5 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
2.3 4.5 GO:1905064 negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
2.3 9.0 GO:1903564 regulation of protein localization to cilium(GO:1903564)
2.2 6.7 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
2.2 8.9 GO:1904379 maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
2.2 11.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.2 39.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
2.2 6.6 GO:2000282 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
2.2 8.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
2.2 6.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.1 8.6 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.1 12.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
2.1 8.5 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
2.1 4.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.0 6.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
2.0 24.4 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
2.0 36.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
2.0 6.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.0 19.9 GO:0032074 negative regulation of nuclease activity(GO:0032074)
2.0 11.8 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
2.0 7.9 GO:0019086 late viral transcription(GO:0019086)
2.0 5.9 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
2.0 9.8 GO:0033590 response to cobalamin(GO:0033590)
2.0 5.9 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
2.0 9.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.9 5.7 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.8 24.0 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
1.8 60.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
1.8 12.8 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.8 16.3 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
1.8 19.9 GO:0045023 G0 to G1 transition(GO:0045023)
1.8 5.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
1.8 14.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
1.7 24.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
1.7 26.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
1.7 10.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.7 5.2 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
1.7 5.1 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
1.7 10.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.7 6.8 GO:0001842 neural fold formation(GO:0001842)
1.7 8.3 GO:0006041 glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
1.7 26.6 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
1.7 5.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
1.6 6.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
1.6 16.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.6 19.4 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
1.6 4.8 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.6 9.6 GO:0048863 stem cell differentiation(GO:0048863)
1.6 4.8 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
1.6 4.8 GO:0014028 mesoderm migration involved in gastrulation(GO:0007509) notochord formation(GO:0014028)
1.6 7.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
1.5 8.9 GO:0035385 Roundabout signaling pathway(GO:0035385)
1.5 4.5 GO:0031645 negative regulation of neurological system process(GO:0031645)
1.5 10.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.5 4.4 GO:0006014 D-ribose metabolic process(GO:0006014)
1.4 5.8 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
1.4 9.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
1.4 17.0 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
1.4 4.2 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
1.4 11.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.4 2.8 GO:0023035 CD40 signaling pathway(GO:0023035)
1.4 8.2 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
1.3 4.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
1.3 6.6 GO:0033625 positive regulation of integrin activation(GO:0033625)
1.3 19.5 GO:0051531 NFAT protein import into nucleus(GO:0051531)
1.3 7.8 GO:0006547 histidine metabolic process(GO:0006547)
1.3 30.2 GO:0006895 Golgi to endosome transport(GO:0006895)
1.2 5.0 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
1.2 10.0 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
1.2 2.5 GO:0060322 head development(GO:0060322)
1.2 19.8 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
1.2 6.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
1.2 12.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
1.2 7.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
1.2 2.4 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
1.2 7.2 GO:0002467 germinal center formation(GO:0002467)
1.2 3.6 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.2 11.9 GO:0015889 cobalamin transport(GO:0015889)
1.2 3.5 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
1.2 6.9 GO:0038161 prolactin signaling pathway(GO:0038161)
1.1 14.9 GO:0010224 response to UV-B(GO:0010224)
1.1 2.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
1.1 5.7 GO:0046968 peptide antigen transport(GO:0046968)
1.1 9.1 GO:0015693 magnesium ion transport(GO:0015693)
1.1 4.5 GO:0042631 cellular response to water deprivation(GO:0042631)
1.1 7.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
1.1 4.5 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
1.1 3.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.1 3.3 GO:0014807 regulation of somitogenesis(GO:0014807)
1.1 7.7 GO:0051106 positive regulation of DNA ligation(GO:0051106)
1.1 8.6 GO:0006013 mannose metabolic process(GO:0006013)
1.1 2.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
1.1 19.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
1.0 12.4 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
1.0 5.2 GO:1902714 negative regulation of interleukin-17 production(GO:0032700) negative regulation of interferon-gamma secretion(GO:1902714)
1.0 6.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
1.0 5.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
1.0 10.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
1.0 7.2 GO:0051414 response to cortisol(GO:0051414)
1.0 4.1 GO:1905007 regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005) positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
1.0 17.3 GO:0046069 cGMP catabolic process(GO:0046069)
1.0 5.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
1.0 5.0 GO:0080009 mRNA methylation(GO:0080009)
1.0 7.0 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
1.0 3.9 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
1.0 6.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
1.0 5.8 GO:0042713 sperm ejaculation(GO:0042713)
1.0 2.9 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
1.0 2.9 GO:0060406 positive regulation of penile erection(GO:0060406)
1.0 3.8 GO:0042483 negative regulation of odontogenesis(GO:0042483)
1.0 8.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
1.0 1.9 GO:0061511 centriole elongation(GO:0061511)
0.9 1.9 GO:0032494 response to peptidoglycan(GO:0032494)
0.9 9.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.9 6.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.9 8.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.9 49.0 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.9 10.0 GO:0006914 autophagy(GO:0006914)
0.9 5.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.9 2.7 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.9 5.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.9 3.5 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.9 4.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.9 5.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.9 4.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.9 9.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.8 2.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.8 17.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.8 20.1 GO:0006829 zinc II ion transport(GO:0006829)
0.8 4.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.8 28.3 GO:0006968 cellular defense response(GO:0006968)
0.8 8.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.8 4.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.8 6.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339) cell-cell recognition(GO:0009988) sperm-egg recognition(GO:0035036)
0.8 4.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.8 1.6 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.8 2.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.8 17.4 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.8 10.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.8 2.4 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.8 3.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.8 3.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.8 6.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.8 27.9 GO:0042554 superoxide anion generation(GO:0042554)
0.8 2.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.8 0.8 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205)
0.7 6.7 GO:0015939 pantothenate metabolic process(GO:0015939)
0.7 28.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.7 2.2 GO:0050894 determination of affect(GO:0050894)
0.7 3.0 GO:0035912 dorsal aorta morphogenesis(GO:0035912)
0.7 8.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.7 8.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.7 4.4 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.7 19.1 GO:0010669 epithelial structure maintenance(GO:0010669)
0.7 6.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.7 2.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.7 56.1 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.7 10.0 GO:0042832 defense response to protozoan(GO:0042832)
0.7 5.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.7 8.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.7 11.2 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.7 2.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.7 7.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.7 9.7 GO:0002449 lymphocyte mediated immunity(GO:0002449)
0.7 11.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.7 21.3 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.7 6.9 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.7 3.4 GO:0089712 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.7 24.8 GO:0051646 mitochondrion localization(GO:0051646)
0.7 8.0 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.7 4.0 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.7 5.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.7 7.2 GO:0051972 regulation of telomerase activity(GO:0051972) positive regulation of telomerase activity(GO:0051973)
0.7 10.5 GO:0006853 carnitine shuttle(GO:0006853)
0.7 1.3 GO:0010966 regulation of phosphate transport(GO:0010966)
0.6 5.8 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.6 4.5 GO:0051601 exocyst localization(GO:0051601)
0.6 7.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) proton-transporting two-sector ATPase complex assembly(GO:0070071) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.6 3.8 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.6 1.3 GO:0002309 T cell proliferation involved in immune response(GO:0002309) interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.6 6.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.6 4.4 GO:0033227 dsRNA transport(GO:0033227)
0.6 1.9 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.6 12.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.6 5.6 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.6 3.1 GO:0022605 ovarian cumulus expansion(GO:0001550) oogenesis stage(GO:0022605) fused antrum stage(GO:0048165)
0.6 8.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.6 5.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.6 5.6 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.6 1.2 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.6 7.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.6 2.4 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) synaptic transmission involved in micturition(GO:0060084)
0.6 1.2 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.6 3.6 GO:0060215 primitive hemopoiesis(GO:0060215)
0.6 1.8 GO:0097155 fasciculation of sensory neuron axon(GO:0097155) fasciculation of motor neuron axon(GO:0097156)
0.6 7.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.6 1.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.6 3.5 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.6 1.7 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.6 1.7 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.6 2.9 GO:0032456 endocytic recycling(GO:0032456)
0.6 7.3 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.6 1.7 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.6 3.4 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.6 21.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.5 3.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.5 4.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.5 1.6 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.5 7.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.5 9.7 GO:0032607 interferon-alpha production(GO:0032607)
0.5 7.4 GO:0006004 fucose metabolic process(GO:0006004)
0.5 9.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.5 3.7 GO:0042426 choline catabolic process(GO:0042426)
0.5 3.7 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.5 4.1 GO:0006265 DNA topological change(GO:0006265)
0.5 8.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.5 4.1 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.5 5.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.5 3.0 GO:0006196 AMP catabolic process(GO:0006196)
0.5 13.2 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.5 22.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.5 2.0 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.5 3.0 GO:0007296 vitellogenesis(GO:0007296)
0.5 8.1 GO:0050890 cognition(GO:0050890)
0.5 16.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.5 1.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.5 9.9 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.5 44.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.5 5.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.5 19.7 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648)
0.5 2.0 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.5 2.9 GO:0001865 NK T cell differentiation(GO:0001865)
0.5 6.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.5 2.9 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.5 2.9 GO:0033504 floor plate development(GO:0033504)
0.5 7.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.5 1.9 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.5 11.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.5 2.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.5 1.4 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.5 3.2 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.5 5.9 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.5 4.1 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.4 2.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.4 2.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.4 2.2 GO:0021759 globus pallidus development(GO:0021759)
0.4 6.6 GO:0048820 hair follicle maturation(GO:0048820)
0.4 2.6 GO:0051693 actin filament capping(GO:0051693)
0.4 6.0 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.4 2.1 GO:0070842 aggresome assembly(GO:0070842)
0.4 3.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.4 9.9 GO:0060325 face morphogenesis(GO:0060325)
0.4 27.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 5.7 GO:0051014 actin filament severing(GO:0051014)
0.4 8.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 3.3 GO:0009642 response to light intensity(GO:0009642)
0.4 9.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.4 2.8 GO:0016198 axon choice point recognition(GO:0016198)
0.4 4.8 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.4 6.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.4 5.1 GO:0051382 kinetochore assembly(GO:0051382)
0.4 3.9 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.4 0.8 GO:0051459 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.4 17.4 GO:0070206 protein trimerization(GO:0070206)
0.4 5.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.4 5.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.4 4.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.4 3.3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.4 9.8 GO:0097576 vacuole fusion(GO:0097576)
0.4 2.9 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.4 4.6 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.4 4.6 GO:0035878 nail development(GO:0035878)
0.3 0.7 GO:0032252 secretory granule localization(GO:0032252)
0.3 7.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 3.1 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.3 1.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.3 5.7 GO:0035411 catenin import into nucleus(GO:0035411)
0.3 2.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 6.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.3 20.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.3 3.6 GO:0034605 cellular response to heat(GO:0034605)
0.3 2.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.3 2.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 1.3 GO:0051182 coenzyme transport(GO:0051182)
0.3 1.6 GO:0030035 microspike assembly(GO:0030035) glomerulus morphogenesis(GO:0072102)
0.3 9.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.3 0.6 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 4.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 4.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.3 1.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3 7.6 GO:0048265 response to pain(GO:0048265)
0.3 11.6 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.3 3.6 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.3 2.7 GO:0090344 negative regulation of cell aging(GO:0090344)
0.3 7.1 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.3 28.5 GO:0009062 fatty acid catabolic process(GO:0009062)
0.3 1.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.3 25.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.3 4.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.3 4.1 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.3 3.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.3 11.5 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.3 11.4 GO:0018149 peptide cross-linking(GO:0018149)
0.3 2.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.3 2.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.3 0.8 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 3.1 GO:0015074 DNA integration(GO:0015074)
0.3 8.9 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.3 18.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 6.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.3 7.6 GO:0003014 renal system process(GO:0003014)
0.3 2.4 GO:0060346 sequestering of TGFbeta in extracellular matrix(GO:0035583) bone trabecula formation(GO:0060346)
0.3 2.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.3 2.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 16.2 GO:1902400 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.3 2.8 GO:0001945 lymph vessel development(GO:0001945)
0.2 2.5 GO:0006600 creatine metabolic process(GO:0006600)
0.2 1.4 GO:0070166 enamel mineralization(GO:0070166)
0.2 1.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 1.7 GO:0033198 response to ATP(GO:0033198)
0.2 2.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 1.9 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.2 6.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.2 1.4 GO:0060137 maternal process involved in parturition(GO:0060137)
0.2 5.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 6.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 3.9 GO:0006298 mismatch repair(GO:0006298)
0.2 1.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 2.0 GO:1903747 regulation of establishment of protein localization to mitochondrion(GO:1903747)
0.2 4.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 0.7 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 6.4 GO:0008038 neuron recognition(GO:0008038)
0.2 4.8 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.2 3.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 8.6 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.2 3.0 GO:0015671 oxygen transport(GO:0015671)
0.2 1.9 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.2 6.5 GO:0042116 macrophage activation(GO:0042116)
0.2 1.4 GO:0001569 patterning of blood vessels(GO:0001569)
0.2 1.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 5.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.2 16.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 3.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 5.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.2 8.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 4.9 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.2 2.2 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.2 1.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 5.2 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.2 2.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 1.0 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 0.2 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.2 3.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.2 2.0 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.2 1.1 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 4.0 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 2.1 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 2.9 GO:0097421 liver regeneration(GO:0097421)
0.1 0.6 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 1.6 GO:0007520 myoblast fusion(GO:0007520)
0.1 8.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 2.9 GO:0048278 vesicle docking(GO:0048278)
0.1 10.3 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 1.0 GO:0008218 bioluminescence(GO:0008218)
0.1 4.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.5 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 4.1 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.1 6.7 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 2.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 4.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.4 GO:0048867 stem cell fate determination(GO:0048867)
0.1 2.3 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 1.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 2.6 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 6.9 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 1.8 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 2.9 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 9.7 GO:0016567 protein ubiquitination(GO:0016567)
0.1 11.7 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 1.2 GO:0045008 depyrimidination(GO:0045008)
0.1 0.6 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 1.9 GO:0070849 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.7 GO:0090045 protein farnesylation(GO:0018343) positive regulation of deacetylase activity(GO:0090045)
0.1 0.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 4.2 GO:0042100 B cell proliferation(GO:0042100)
0.1 3.5 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.1 1.8 GO:0016577 histone demethylation(GO:0016577)
0.1 14.8 GO:0007411 axon guidance(GO:0007411)
0.1 9.9 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.1 9.2 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.1 1.3 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) centromere complex assembly(GO:0034508) CENP-A containing chromatin organization(GO:0061641)
0.1 6.0 GO:0007588 excretion(GO:0007588)
0.1 1.1 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 2.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 3.4 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.0 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 3.1 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.9 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1 1.9 GO:0042278 purine nucleoside metabolic process(GO:0042278)
0.1 4.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 1.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 3.7 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 1.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 5.1 GO:0030010 establishment of cell polarity(GO:0030010)
0.1 3.3 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.7 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 2.8 GO:0030317 sperm motility(GO:0030317)
0.1 2.7 GO:0050770 regulation of axonogenesis(GO:0050770)
0.1 1.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 2.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.9 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.1 1.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 2.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.7 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.9 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 2.8 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 1.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.0 GO:0019228 neuronal action potential(GO:0019228)
0.0 1.2 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 1.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 1.4 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.7 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 2.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.7 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.4 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0060177 regulation of angiotensin levels in blood(GO:0002002) angiotensin maturation(GO:0002003) regulation of angiotensin metabolic process(GO:0060177)
0.0 2.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.9 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 1.2 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.9 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 1.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 1.4 GO:0006954 inflammatory response(GO:0006954)
0.0 0.2 GO:0042552 myelination(GO:0042552)
0.0 0.1 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 1.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
19.2 57.5 GO:0061673 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
16.2 48.5 GO:0071020 post-spliceosomal complex(GO:0071020)
10.9 65.4 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
9.0 36.1 GO:1990745 EARP complex(GO:1990745)
6.5 19.4 GO:0044609 DBIRD complex(GO:0044609)
5.2 41.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
4.9 19.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
4.2 4.2 GO:0098536 deuterosome(GO:0098536)
4.0 20.2 GO:0002080 acrosomal membrane(GO:0002080)
3.9 19.5 GO:0070847 core mediator complex(GO:0070847)
3.8 19.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
3.8 37.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
3.5 24.3 GO:0097427 microtubule bundle(GO:0097427)
3.4 23.6 GO:0033269 internode region of axon(GO:0033269)
3.2 22.5 GO:0019815 B cell receptor complex(GO:0019815)
2.6 10.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
2.5 20.3 GO:0032010 phagolysosome(GO:0032010)
2.5 4.9 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
2.3 9.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
2.2 15.6 GO:0044194 cytolytic granule(GO:0044194)
2.1 10.4 GO:0045298 tubulin complex(GO:0045298)
2.0 22.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
2.0 10.0 GO:0044530 supraspliceosomal complex(GO:0044530)
1.9 42.9 GO:0000242 pericentriolar material(GO:0000242)
1.9 26.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.9 9.3 GO:0089701 U2AF(GO:0089701)
1.7 38.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.7 30.8 GO:0097342 ripoptosome(GO:0097342)
1.7 5.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
1.7 5.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.7 5.0 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
1.6 9.4 GO:1990037 Lewy body core(GO:1990037)
1.5 10.3 GO:0032584 growth cone membrane(GO:0032584)
1.5 5.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.4 24.6 GO:0033270 paranode region of axon(GO:0033270)
1.4 8.6 GO:1990769 proximal neuron projection(GO:1990769)
1.4 9.9 GO:0036021 endolysosome lumen(GO:0036021)
1.4 19.6 GO:0035631 CD40 receptor complex(GO:0035631)
1.4 51.1 GO:0042629 mast cell granule(GO:0042629)
1.4 15.1 GO:0097443 sorting endosome(GO:0097443)
1.4 4.1 GO:0072563 endothelial microparticle(GO:0072563)
1.3 4.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
1.3 8.0 GO:1990130 Iml1 complex(GO:1990130)
1.2 10.0 GO:0000322 storage vacuole(GO:0000322)
1.2 7.3 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
1.2 17.0 GO:0035102 PRC1 complex(GO:0035102)
1.2 3.6 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
1.2 5.9 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
1.1 7.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
1.1 7.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.1 57.3 GO:0005801 cis-Golgi network(GO:0005801)
1.1 2.1 GO:0032009 early phagosome(GO:0032009)
1.1 9.5 GO:0032039 integrator complex(GO:0032039)
1.1 5.3 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.0 5.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.0 10.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.0 34.7 GO:0005720 nuclear heterochromatin(GO:0005720)
1.0 6.9 GO:0072487 MSL complex(GO:0072487)
1.0 16.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.9 10.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.9 5.2 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.9 7.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.8 12.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.8 10.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.8 5.0 GO:0005770 late endosome(GO:0005770)
0.8 8.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.8 9.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.8 5.7 GO:0001520 outer dense fiber(GO:0001520)
0.8 4.5 GO:0030133 transport vesicle(GO:0030133)
0.7 19.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.7 7.4 GO:0012506 vesicle membrane(GO:0012506)
0.7 2.9 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.7 2.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.7 38.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.7 2.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.7 6.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.7 3.5 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.7 37.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.6 7.7 GO:0031045 dense core granule(GO:0031045)
0.6 4.5 GO:0005577 fibrinogen complex(GO:0005577)
0.6 9.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.6 8.0 GO:0030897 HOPS complex(GO:0030897)
0.6 6.7 GO:0005642 annulate lamellae(GO:0005642)
0.6 7.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 6.3 GO:0032797 SMN complex(GO:0032797)
0.6 2.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.6 7.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.5 5.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.5 3.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.5 4.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.5 2.9 GO:0031594 neuromuscular junction(GO:0031594)
0.5 0.9 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.5 33.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 10.7 GO:0046930 pore complex(GO:0046930)
0.4 14.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.4 2.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 12.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.4 21.4 GO:0031904 endosome lumen(GO:0031904)
0.4 2.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 3.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.4 6.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.4 4.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 20.2 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.4 3.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 5.1 GO:0000815 ESCRT III complex(GO:0000815)
0.4 9.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 3.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.4 3.7 GO:0071953 elastic fiber(GO:0071953)
0.4 3.5 GO:0042587 glycogen granule(GO:0042587)
0.3 7.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 5.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 4.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.3 7.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.3 3.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 5.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 4.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.3 1.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.3 5.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 3.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 3.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 4.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 25.4 GO:0005814 centriole(GO:0005814)
0.3 4.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 5.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 4.0 GO:0097228 sperm principal piece(GO:0097228)
0.2 3.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 0.9 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.2 0.7 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.2 45.0 GO:0001726 ruffle(GO:0001726)
0.2 1.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.2 18.0 GO:0042734 presynaptic membrane(GO:0042734)
0.2 36.1 GO:0005769 early endosome(GO:0005769)
0.2 3.4 GO:0042599 lamellar body(GO:0042599)
0.2 0.6 GO:0033565 ESCRT-0 complex(GO:0033565)
0.2 7.5 GO:0000791 euchromatin(GO:0000791)
0.2 16.5 GO:0043195 terminal bouton(GO:0043195)
0.2 10.4 GO:0005938 cell cortex(GO:0005938)
0.2 1.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 0.8 GO:0051286 cell tip(GO:0051286)
0.2 0.6 GO:0060187 cell pole(GO:0060187)
0.2 3.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 0.7 GO:0005899 insulin receptor complex(GO:0005899)
0.2 10.9 GO:0031526 brush border membrane(GO:0031526)
0.2 4.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 3.7 GO:0071141 SMAD protein complex(GO:0071141)
0.2 11.0 GO:0031902 late endosome membrane(GO:0031902)
0.2 22.2 GO:0031901 early endosome membrane(GO:0031901)
0.2 1.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 31.9 GO:0043235 receptor complex(GO:0043235)
0.2 0.9 GO:0005927 muscle tendon junction(GO:0005927)
0.2 7.9 GO:0001533 cornified envelope(GO:0001533)
0.1 0.9 GO:0005883 neurofilament(GO:0005883)
0.1 5.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 7.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 9.1 GO:0005768 endosome(GO:0005768)
0.1 1.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 27.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 12.4 GO:0035579 specific granule membrane(GO:0035579)
0.1 2.1 GO:0030914 STAGA complex(GO:0030914)
0.1 2.0 GO:0032059 bleb(GO:0032059)
0.1 26.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 2.9 GO:0030175 filopodium(GO:0030175)
0.1 2.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 13.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 32.6 GO:0045177 apical part of cell(GO:0045177)
0.1 393.5 GO:0016021 integral component of membrane(GO:0016021)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 4.9 GO:0005581 collagen trimer(GO:0005581)
0.1 5.6 GO:0045202 synapse(GO:0045202)
0.1 1.7 GO:0005861 troponin complex(GO:0005861)
0.1 2.0 GO:0031519 PcG protein complex(GO:0031519)
0.1 1.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 16.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 3.2 GO:0031514 motile cilium(GO:0031514)
0.0 1.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.8 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.8 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 103.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
9.8 29.4 GO:0004913 interleukin-4 receptor activity(GO:0004913)
9.3 65.4 GO:0030369 ICAM-3 receptor activity(GO:0030369)
8.5 25.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
8.1 24.3 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
7.5 44.9 GO:0042610 CD8 receptor binding(GO:0042610)
7.2 7.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
5.7 11.3 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
5.5 16.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
5.1 61.6 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
4.8 23.9 GO:0023024 MHC class I protein complex binding(GO:0023024)
4.6 18.5 GO:0032810 sterol response element binding(GO:0032810)
4.3 21.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
4.3 55.5 GO:0051011 microtubule minus-end binding(GO:0051011)
4.2 12.6 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
4.1 16.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
3.7 29.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
3.6 14.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
3.6 10.9 GO:0015235 cobalamin transporter activity(GO:0015235)
3.5 10.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
3.4 61.7 GO:0019992 diacylglycerol binding(GO:0019992)
3.4 10.2 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
3.3 9.9 GO:0032089 NACHT domain binding(GO:0032089)
3.1 22.0 GO:0042608 T cell receptor binding(GO:0042608)
3.1 36.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
3.0 12.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
3.0 56.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.6 7.9 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
2.6 10.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
2.6 7.7 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
2.5 10.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
2.5 40.0 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
2.5 7.5 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
2.4 14.6 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
2.4 14.3 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
2.3 13.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
2.2 6.7 GO:0016297 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
2.2 6.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
2.2 15.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
2.2 6.6 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
2.2 39.6 GO:0005522 profilin binding(GO:0005522)
2.2 23.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.1 8.5 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
2.1 12.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
2.1 4.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
2.0 6.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
2.0 20.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.0 24.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
2.0 7.9 GO:0016841 ammonia-lyase activity(GO:0016841)
1.9 15.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
1.9 11.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.9 32.0 GO:0070513 death domain binding(GO:0070513)
1.9 9.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
1.9 9.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.8 20.3 GO:0030274 LIM domain binding(GO:0030274)
1.7 5.2 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
1.7 5.1 GO:0032767 copper-dependent protein binding(GO:0032767)
1.7 5.1 GO:0035501 MH1 domain binding(GO:0035501)
1.7 5.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.7 5.0 GO:0004040 amidase activity(GO:0004040)
1.7 5.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.7 8.3 GO:0042289 MHC class II protein binding(GO:0042289)
1.6 9.8 GO:0003998 acylphosphatase activity(GO:0003998)
1.6 11.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.6 6.3 GO:0005124 scavenger receptor binding(GO:0005124)
1.5 10.8 GO:0017002 activin-activated receptor activity(GO:0017002)
1.5 28.2 GO:0070300 phosphatidic acid binding(GO:0070300)
1.5 11.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
1.5 4.4 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
1.5 4.4 GO:0098770 FBXO family protein binding(GO:0098770)
1.4 4.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.4 12.7 GO:0045125 bioactive lipid receptor activity(GO:0045125) lysophosphatidic acid receptor activity(GO:0070915)
1.4 12.6 GO:0003680 AT DNA binding(GO:0003680)
1.4 6.9 GO:0004925 prolactin receptor activity(GO:0004925)
1.4 8.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.4 59.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
1.4 30.4 GO:0050321 tau-protein kinase activity(GO:0050321)
1.4 59.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
1.4 20.3 GO:0042609 CD4 receptor binding(GO:0042609)
1.3 6.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
1.3 16.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.3 7.9 GO:0015057 thrombin receptor activity(GO:0015057)
1.3 150.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
1.3 3.8 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
1.3 12.8 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
1.3 3.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.2 5.0 GO:0034057 RNA strand-exchange activity(GO:0034057)
1.2 8.6 GO:0031730 CCR1 chemokine receptor binding(GO:0031726) CCR5 chemokine receptor binding(GO:0031730)
1.2 6.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.2 17.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.2 20.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
1.1 4.6 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
1.1 3.4 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
1.1 4.5 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.1 10.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.1 3.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
1.0 5.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
1.0 3.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
1.0 5.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
1.0 18.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
1.0 12.1 GO:0045159 myosin II binding(GO:0045159)
1.0 7.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.0 8.9 GO:0048495 Roundabout binding(GO:0048495)
1.0 2.9 GO:0001596 angiotensin type I receptor activity(GO:0001596)
1.0 3.9 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
1.0 3.8 GO:0008384 IkappaB kinase activity(GO:0008384)
0.9 3.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9 3.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.9 10.8 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.9 15.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.9 3.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.9 1.7 GO:1904288 BAT3 complex binding(GO:1904288)
0.9 4.3 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.9 13.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.9 5.2 GO:0000150 recombinase activity(GO:0000150)
0.9 2.6 GO:0032090 Pyrin domain binding(GO:0032090)
0.9 5.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.9 7.7 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.8 5.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.8 11.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.8 13.7 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.8 5.6 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.8 3.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.8 71.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.8 16.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.8 7.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.8 37.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.7 2.2 GO:0031877 somatostatin receptor binding(GO:0031877)
0.7 10.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.7 4.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.7 9.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.7 2.9 GO:0031685 adenosine receptor binding(GO:0031685)
0.7 3.6 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.7 3.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.7 6.9 GO:0008417 fucosyltransferase activity(GO:0008417)
0.7 6.2 GO:0045499 chemorepellent activity(GO:0045499)
0.7 8.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.7 3.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.7 14.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.7 11.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.7 2.0 GO:0035500 MH2 domain binding(GO:0035500)
0.7 7.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.7 3.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.7 9.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.6 4.5 GO:0000149 SNARE binding(GO:0000149)
0.6 4.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.6 3.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.6 3.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.6 2.4 GO:0001855 complement component C4b binding(GO:0001855)
0.6 9.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.6 17.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.6 8.3 GO:0051787 misfolded protein binding(GO:0051787)
0.6 6.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.6 25.4 GO:0030332 cyclin binding(GO:0030332)
0.6 3.5 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.6 13.5 GO:0071949 FAD binding(GO:0071949)
0.6 4.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.6 17.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.6 4.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.6 3.3 GO:0089720 caspase binding(GO:0089720)
0.5 26.2 GO:0015485 cholesterol binding(GO:0015485)
0.5 6.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.5 2.1 GO:0042805 actinin binding(GO:0042805)
0.5 3.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 3.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.5 4.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114) galactose binding(GO:0005534)
0.5 6.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.5 10.7 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.5 2.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.5 14.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.5 10.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.5 2.8 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.5 6.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.5 5.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.5 6.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 2.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.4 5.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 4.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.4 2.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.4 9.9 GO:0022829 wide pore channel activity(GO:0022829)
0.4 1.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.4 39.8 GO:0019905 syntaxin binding(GO:0019905)
0.4 1.7 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.4 11.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.4 8.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.4 11.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 1.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.4 2.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 6.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.4 1.6 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.4 7.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.4 14.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 9.7 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.4 9.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.4 0.8 GO:0030911 TPR domain binding(GO:0030911)
0.4 6.9 GO:0035497 cAMP response element binding(GO:0035497)
0.4 3.8 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.4 1.1 GO:0031692 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762) platelet activating factor receptor binding(GO:0031859)
0.4 9.6 GO:0005123 death receptor binding(GO:0005123)
0.4 8.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 1.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 21.2 GO:0050681 androgen receptor binding(GO:0050681)
0.4 8.6 GO:0008198 ferrous iron binding(GO:0008198)
0.4 3.2 GO:0004969 histamine receptor activity(GO:0004969)
0.4 11.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.3 13.2 GO:0043394 proteoglycan binding(GO:0043394)
0.3 1.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 5.9 GO:0005537 mannose binding(GO:0005537)
0.3 7.2 GO:0043274 phospholipase binding(GO:0043274)
0.3 1.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.3 10.7 GO:0042169 SH2 domain binding(GO:0042169)
0.3 3.7 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.3 11.3 GO:0005518 collagen binding(GO:0005518)
0.3 3.9 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.3 10.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.3 1.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.3 1.9 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.3 1.9 GO:0050700 CARD domain binding(GO:0050700)
0.3 2.5 GO:0004111 creatine kinase activity(GO:0004111)
0.3 10.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.3 3.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 3.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 2.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 7.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 5.7 GO:0097602 cullin family protein binding(GO:0097602)
0.3 4.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3 0.9 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.3 15.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 26.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.3 4.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.3 2.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 1.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 6.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.3 2.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 4.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 2.7 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 2.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.3 8.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 5.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 2.1 GO:0004064 arylesterase activity(GO:0004064)
0.3 6.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 3.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 4.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.3 7.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.0 GO:0034452 dynactin binding(GO:0034452)
0.2 70.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 5.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 2.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 5.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 0.9 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.2 1.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 3.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 4.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 7.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 1.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 4.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.6 GO:0071837 HMG box domain binding(GO:0071837)
0.2 1.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.2 4.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 7.6 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2 188.9 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2 46.4 GO:0008236 serine-type peptidase activity(GO:0008236)
0.2 2.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 2.0 GO:0005158 insulin receptor binding(GO:0005158)
0.2 11.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 2.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 0.8 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.2 43.5 GO:0005096 GTPase activator activity(GO:0005096)
0.2 16.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 5.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 1.9 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 1.7 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.7 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 3.3 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 2.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 4.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 3.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 7.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.7 GO:0031404 chloride ion binding(GO:0031404)
0.1 3.0 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 5.1 GO:0008009 chemokine activity(GO:0008009)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 8.0 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.6 GO:1990460 leptin receptor binding(GO:1990460)
0.1 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 42.4 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 0.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 2.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.7 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 21.5 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 2.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.1 GO:0005109 frizzled binding(GO:0005109)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 2.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 29.7 GO:0004888 transmembrane signaling receptor activity(GO:0004888)
0.1 1.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 6.6 GO:0046873 metal ion transmembrane transporter activity(GO:0046873)
0.1 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.1 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.2 GO:0070728 leucine binding(GO:0070728)
0.1 1.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 1.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 2.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 2.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 4.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.3 GO:0030546 receptor activator activity(GO:0030546)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 13.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
2.2 128.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
1.9 17.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
1.8 91.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.6 162.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
1.5 21.7 PID S1P S1P4 PATHWAY S1P4 pathway
1.4 73.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
1.4 77.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
1.4 89.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
1.3 89.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
1.0 17.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.0 13.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.8 7.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.8 30.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.8 3.9 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.8 0.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.7 18.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.7 19.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.7 28.4 PID BCR 5PATHWAY BCR signaling pathway
0.7 11.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.6 6.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.6 20.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.6 19.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.6 3.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.6 26.1 NABA COLLAGENS Genes encoding collagen proteins
0.5 24.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.5 24.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.5 13.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.4 16.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.4 14.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.4 9.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 14.3 PID ALK1 PATHWAY ALK1 signaling events
0.4 63.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4 6.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.3 5.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.3 6.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.3 19.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 117.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.3 6.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 6.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.3 18.1 PID ATR PATHWAY ATR signaling pathway
0.3 9.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.3 4.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 3.2 PID NOTCH PATHWAY Notch signaling pathway
0.2 2.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 7.0 PID BMP PATHWAY BMP receptor signaling
0.2 13.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 4.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 3.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 2.9 PID TNF PATHWAY TNF receptor signaling pathway
0.2 16.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 7.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.2 2.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 7.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 1.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 9.3 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.5 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.8 PID INSULIN PATHWAY Insulin Pathway
0.1 2.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 2.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 24.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 6.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 3.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 0.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 1.0 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.1 PID MYC PATHWAY C-MYC pathway
0.1 1.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.1 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 57.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
2.9 60.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
2.7 62.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
2.0 33.9 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
1.9 5.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.5 48.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
1.5 69.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.2 109.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.1 19.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
1.1 48.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.1 4.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.1 9.7 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.1 14.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.1 11.7 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.8 9.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.8 15.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.8 9.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.8 9.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.8 19.6 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.7 2.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.7 21.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.7 1.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.7 20.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.7 47.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.6 11.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.6 6.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.6 20.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.6 6.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.6 8.6 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.6 11.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.6 35.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.6 21.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.6 4.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.5 12.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.5 32.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.5 33.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 2.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.5 3.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.5 9.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5 2.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.5 9.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.5 11.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.5 17.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.5 83.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.5 9.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.5 7.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.5 10.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.4 30.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.4 9.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.4 15.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 2.2 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.4 4.8 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.4 12.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.4 7.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.4 36.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.4 3.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 6.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.4 17.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.4 4.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 9.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.3 5.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 101.6 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.3 6.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.3 26.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 81.5 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.3 1.6 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.3 7.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 7.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.3 3.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 2.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 2.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 11.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 3.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 5.7 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 1.4 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.2 3.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 5.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 4.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 0.9 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 19.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 8.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 2.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 9.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 4.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.5 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.1 2.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 2.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.9 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.1 0.6 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 5.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 5.9 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.1 1.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 0.8 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.3 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse