averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
FLI1 | hg19_v2_chr11_+_128563652_128563689, hg19_v2_chr11_+_128562372_128562397, hg19_v2_chr11_+_128634589_128634685, hg19_v2_chr11_+_128563948_128564003 | 0.66 | 1.9e-28 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.0 | 114.7 | GO:0019336 | phenol-containing compound catabolic process(GO:0019336) |
1.8 | 60.7 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
19.2 | 57.5 | GO:1902846 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
0.7 | 56.1 | GO:0032945 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
3.2 | 50.5 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.9 | 49.0 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) |
12.1 | 48.5 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
0.5 | 44.5 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
2.6 | 42.2 | GO:0048712 | negative regulation of astrocyte differentiation(GO:0048712) |
2.2 | 39.9 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 393.5 | GO:0016021 | integral component of membrane(GO:0016021) |
10.9 | 65.4 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
19.2 | 57.5 | GO:0061673 | cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673) |
1.1 | 57.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
1.4 | 51.1 | GO:0042629 | mast cell granule(GO:0042629) |
16.2 | 48.5 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
0.2 | 45.0 | GO:0001726 | ruffle(GO:0001726) |
1.9 | 42.9 | GO:0000242 | pericentriolar material(GO:0000242) |
5.2 | 41.5 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.7 | 38.6 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 188.9 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
1.3 | 150.3 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
14.7 | 103.2 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
0.8 | 71.0 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.2 | 70.6 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
9.3 | 65.4 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
3.4 | 61.7 | GO:0019992 | diacylglycerol binding(GO:0019992) |
5.1 | 61.6 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
1.4 | 59.5 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
1.4 | 59.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 162.8 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
2.2 | 128.6 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
0.3 | 117.7 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
1.8 | 91.1 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
1.3 | 89.6 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
1.4 | 89.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
1.4 | 77.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
1.4 | 73.3 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
0.4 | 63.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.8 | 30.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 109.9 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.3 | 101.6 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
0.5 | 83.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.3 | 81.5 | REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
1.5 | 69.2 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
2.7 | 62.4 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
2.9 | 60.1 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
3.6 | 57.5 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
1.5 | 48.9 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
1.1 | 48.7 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |