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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOSL1

Z-value: 1.54

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Transcription factors associated with FOSL1

Gene Symbol Gene ID Gene Info
FOSL1
ENSG00000175592.4 FOS like 1, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL1hg19_v2_chr11_-_65667884_656678950.531.7e-17Click!

Activity profile of FOSL1 motif

Sorted Z-values of FOSL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_113247543 47.45 ENST00000414971.1
ENST00000534717.1
RHOC
ras homolog family member C
chr1_+_223889285 45.30 ENST00000433674.2
CAPN2
calpain 2, (m/II) large subunit
chr1_-_151965048 35.32 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr5_+_135394840 30.16 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr1_+_156084461 29.84 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr11_-_2950642 26.30 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr1_+_156096336 23.87 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr16_-_69760409 22.99 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1
NAD(P)H dehydrogenase, quinone 1
chr7_+_55177416 22.60 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr15_-_60690163 21.18 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr1_+_223900034 20.79 ENST00000295006.5
CAPN2
calpain 2, (m/II) large subunit
chr11_-_65667997 19.79 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr1_-_95007193 19.66 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr10_+_17270214 19.15 ENST00000544301.1
VIM
vimentin
chr11_-_65667884 18.72 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr6_-_138428613 18.49 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr12_+_13349650 18.44 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr7_-_107643674 18.30 ENST00000222399.6
LAMB1
laminin, beta 1
chr18_+_21452804 18.23 ENST00000269217.6
LAMA3
laminin, alpha 3
chr1_+_156095951 17.62 ENST00000448611.2
ENST00000368297.1
LMNA
lamin A/C
chr5_+_138089100 16.85 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr1_-_154943002 16.17 ENST00000606391.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr1_-_152009460 15.54 ENST00000271638.2
S100A11
S100 calcium binding protein A11
chr1_+_27189631 15.50 ENST00000339276.4
SFN
stratifin
chr11_+_394196 15.48 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr11_+_35198243 15.30 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr1_-_154943212 15.13 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr6_+_83072923 15.11 ENST00000535040.1
TPBG
trophoblast glycoprotein
chr3_-_149095652 14.53 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr15_+_22892663 14.23 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
CYFIP1
cytoplasmic FMR1 interacting protein 1
chr11_+_101983176 13.90 ENST00000524575.1
YAP1
Yes-associated protein 1
chr12_-_56122761 13.57 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
CD63
CD63 molecule
chr10_+_121410882 13.46 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr7_+_48128194 13.21 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1
uridine phosphorylase 1
chr1_-_159894319 13.13 ENST00000320307.4
TAGLN2
transgelin 2
chr12_-_56122426 13.04 ENST00000551173.1
CD63
CD63 molecule
chr18_+_21452964 13.00 ENST00000587184.1
LAMA3
laminin, alpha 3
chr11_+_35198118 12.90 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44
CD44 molecule (Indian blood group)
chr7_+_48128316 12.88 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr1_+_169077172 12.77 ENST00000499679.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr4_+_169753156 12.74 ENST00000393726.3
ENST00000507735.1
PALLD
palladin, cytoskeletal associated protein
chr11_-_6341844 12.67 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr17_+_35851570 12.56 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr3_-_149293990 12.52 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr6_-_31704282 12.40 ENST00000375784.3
ENST00000375779.2
CLIC1
chloride intracellular channel 1
chr1_+_150480551 12.34 ENST00000369049.4
ENST00000369047.4
ECM1
extracellular matrix protein 1
chr1_+_150480576 11.95 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr11_-_102668879 11.87 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr12_-_53343602 11.87 ENST00000546897.1
ENST00000552551.1
KRT8
keratin 8
chr3_+_183894566 11.74 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr11_-_64013288 11.41 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_-_151034734 11.20 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chrX_-_15511438 11.17 ENST00000380420.5
PIR
pirin (iron-binding nuclear protein)
chr1_-_209824643 11.11 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr20_-_62129163 10.82 ENST00000298049.7
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr21_-_27542972 10.54 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
APP
amyloid beta (A4) precursor protein
chr14_+_103801140 10.51 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
EIF5
eukaryotic translation initiation factor 5
chr11_-_66103867 10.34 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr17_-_39743139 10.04 ENST00000167586.6
KRT14
keratin 14
chr11_-_64013663 9.97 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr7_+_73245193 9.70 ENST00000340958.2
CLDN4
claudin 4
chr19_+_35645817 9.67 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr6_-_84140757 9.57 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr11_+_114310237 9.50 ENST00000539119.1
REXO2
RNA exonuclease 2
chr16_+_89988259 9.48 ENST00000554444.1
ENST00000556565.1
TUBB3
Tubulin beta-3 chain
chr7_+_116312411 9.16 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chrX_-_153285395 9.09 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chrX_-_153285251 8.90 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr17_+_49230897 8.73 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME1
NME1-NME2
NME2
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr20_+_33759854 8.71 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr4_+_74606223 8.66 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr17_-_65362678 8.60 ENST00000357146.4
ENST00000356126.3
PSMD12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr9_+_140172200 8.48 ENST00000357503.2
TOR4A
torsin family 4, member A
chrX_-_10851762 8.44 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr11_-_6341724 8.42 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr8_+_26150628 8.38 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr8_-_141774467 8.29 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr1_+_153003671 8.25 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr19_+_35645618 8.25 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5
chr7_-_96339132 8.21 ENST00000413065.1
SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr9_-_127177703 8.18 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
PSMB7
proteasome (prosome, macropain) subunit, beta type, 7
chr17_-_79481666 8.08 ENST00000575659.1
ACTG1
actin, gamma 1
chr13_+_78109804 7.67 ENST00000535157.1
SCEL
sciellin
chr13_+_78109884 7.48 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr3_-_81792780 7.46 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr3_+_69928256 6.99 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr5_+_72143988 6.92 ENST00000506351.2
TNPO1
transportin 1
chr1_+_26605618 6.91 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr11_+_706113 6.78 ENST00000318562.8
ENST00000533256.1
ENST00000534755.1
EPS8L2
EPS8-like 2
chr11_+_46402297 6.75 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr1_-_153066998 6.73 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr7_+_23286182 6.72 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr14_-_71107921 6.62 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr18_+_61554932 6.57 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr17_-_39780819 6.57 ENST00000311208.8
KRT17
keratin 17
chr17_-_39769005 6.55 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr1_+_26606608 6.53 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr12_+_110718921 6.49 ENST00000308664.6
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chrX_-_153718953 6.47 ENST00000369649.4
ENST00000393586.1
SLC10A3
solute carrier family 10, member 3
chr16_+_30077055 6.38 ENST00000564595.2
ENST00000569798.1
ALDOA
aldolase A, fructose-bisphosphate
chr15_+_64428529 6.34 ENST00000560861.1
SNX1
sorting nexin 1
chr22_-_30642782 6.33 ENST00000249075.3
LIF
leukemia inhibitory factor
chr21_-_27543425 6.21 ENST00000448388.2
APP
amyloid beta (A4) precursor protein
chr6_+_125540951 6.21 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr20_+_4666882 6.20 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr17_-_73781567 5.85 ENST00000586607.1
H3F3B
H3 histone, family 3B (H3.3B)
chr19_+_36630961 5.79 ENST00000587718.1
ENST00000592483.1
ENST00000590874.1
ENST00000588815.1
CAPNS1
calpain, small subunit 1
chr16_+_30751953 5.70 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr19_+_36630454 5.68 ENST00000246533.3
CAPNS1
calpain, small subunit 1
chr1_+_152956549 5.68 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr1_-_109968973 5.66 ENST00000271308.4
ENST00000538610.1
PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr9_+_140135665 5.58 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr3_+_30648066 5.47 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr12_+_6644443 5.45 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr3_+_30647994 5.45 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr18_+_61143994 5.42 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr11_-_14541872 5.34 ENST00000419365.2
ENST00000530457.1
ENST00000532256.1
ENST00000533068.1
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr3_+_69134080 5.30 ENST00000273258.3
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr5_+_140729649 5.26 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr3_+_187930719 5.26 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr11_-_111783919 5.22 ENST00000531198.1
ENST00000533879.1
CRYAB
crystallin, alpha B
chr17_+_74381343 5.09 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr2_+_231921574 4.94 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr15_-_56209306 4.92 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr18_+_55888767 4.92 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr19_+_36630855 4.90 ENST00000589146.1
CAPNS1
calpain, small subunit 1
chr11_-_66104237 4.82 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr1_+_36621697 4.81 ENST00000373150.4
ENST00000373151.2
MAP7D1
MAP7 domain containing 1
chr12_+_56473628 4.78 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr7_-_96339167 4.76 ENST00000444799.1
ENST00000417009.1
ENST00000248566.2
SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr17_+_57697216 4.70 ENST00000393043.1
ENST00000269122.3
CLTC
clathrin, heavy chain (Hc)
chr7_+_22766766 4.67 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr11_-_111784005 4.66 ENST00000527899.1
CRYAB
crystallin, alpha B
chr3_+_69134124 4.62 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr14_-_75643296 4.58 ENST00000303575.4
TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr1_+_36621529 4.58 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr1_+_183155373 4.57 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr19_+_39279838 4.54 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr17_-_39942940 4.54 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP
junction plakoglobin
chr11_-_62323702 4.53 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr21_-_36421401 4.48 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr2_-_85641162 4.46 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG
capping protein (actin filament), gelsolin-like
chr1_-_150208363 4.44 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_+_56546363 4.37 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr16_+_74330673 4.33 ENST00000219313.4
ENST00000540379.1
ENST00000567958.1
ENST00000568615.2
PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr17_-_73150629 4.26 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1
hematological and neurological expressed 1
chr3_-_48632593 4.21 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr16_+_30077098 4.17 ENST00000395240.3
ENST00000566846.1
ALDOA
aldolase A, fructose-bisphosphate
chr16_-_66968055 4.13 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chr1_-_150208291 4.13 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_-_66968265 4.06 ENST00000567511.1
ENST00000422424.2
FAM96B
family with sequence similarity 96, member B
chr5_+_140868717 4.05 ENST00000252087.1
PCDHGC5
protocadherin gamma subfamily C, 5
chr15_+_41136586 4.03 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr5_+_179247759 4.00 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1
sequestosome 1
chr10_+_88428206 3.97 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3
LIM domain binding 3
chr1_-_153013588 3.95 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr3_-_98241760 3.92 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1
claudin domain containing 1
chr1_+_155107820 3.82 ENST00000484157.1
SLC50A1
solute carrier family 50 (sugar efflux transporter), member 1
chr2_-_200322723 3.78 ENST00000417098.1
SATB2
SATB homeobox 2
chr11_-_111794446 3.77 ENST00000527950.1
CRYAB
crystallin, alpha B
chr10_+_123872483 3.75 ENST00000369001.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr12_-_91573249 3.73 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr8_-_143823816 3.68 ENST00000246515.1
SLURP1
secreted LY6/PLAUR domain containing 1
chr12_-_54813229 3.60 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr13_-_110438914 3.55 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr11_-_66103932 3.54 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr1_-_27816641 3.43 ENST00000430629.2
WASF2
WAS protein family, member 2
chr3_-_98241358 3.41 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr3_-_32022733 3.40 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chr8_+_126442563 3.35 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr8_-_67974552 3.32 ENST00000357849.4
COPS5
COP9 signalosome subunit 5
chr2_+_152214098 3.30 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr6_+_44214824 3.28 ENST00000371646.5
ENST00000353801.3
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr12_+_56546223 3.27 ENST00000550443.1
ENST00000207437.5
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr1_-_153029980 3.25 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr10_-_93392811 3.20 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr21_-_36421535 3.20 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr2_+_172544011 3.15 ENST00000508530.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr6_+_64281906 3.10 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr16_+_57662419 3.09 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr15_+_44829255 3.07 ENST00000261868.5
ENST00000424492.3
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr3_+_69812877 3.06 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr21_-_36421626 3.05 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr17_+_79650962 2.97 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr2_+_28615669 2.94 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr1_-_160990886 2.91 ENST00000537746.1
F11R
F11 receptor
chr16_+_57662138 2.89 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chr15_+_89631381 2.88 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr2_+_47596287 2.87 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr10_-_98346801 2.86 ENST00000371142.4
TM9SF3
transmembrane 9 superfamily member 3
chr18_-_25616519 2.84 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr3_-_37216055 2.83 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr7_+_99006232 2.82 ENST00000403633.2
BUD31
BUD31 homolog (S. cerevisiae)
chr11_+_35639735 2.73 ENST00000317811.4
FJX1
four jointed box 1 (Drosophila)
chr5_+_150020214 2.69 ENST00000307662.4
SYNPO
synaptopodin
chr17_+_7123125 2.58 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
ACADVL
acyl-CoA dehydrogenase, very long chain
chr11_+_82783097 2.56 ENST00000501011.2
ENST00000527627.1
ENST00000526795.1
ENST00000533528.1
ENST00000533708.1
ENST00000534499.1
RAB30-AS1
RAB30 antisense RNA 1 (head to head)
chr15_+_41136216 2.55 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr7_+_128095945 2.55 ENST00000257696.4
HILPDA
hypoxia inducible lipid droplet-associated
chr21_+_33031935 2.54 ENST00000270142.6
ENST00000389995.4
SOD1
superoxide dismutase 1, soluble

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
14.3 71.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
7.9 47.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
7.5 22.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
7.1 21.2 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
6.6 19.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
6.5 26.1 GO:0006218 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
6.4 38.5 GO:0007296 vitellogenesis(GO:0007296)
6.0 17.9 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
5.9 17.7 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
4.6 18.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
4.0 20.0 GO:0002159 desmosome assembly(GO:0002159)
3.6 10.9 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
3.6 14.2 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
3.5 28.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
3.4 16.8 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
3.2 12.8 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
3.2 60.2 GO:0016540 protein autoprocessing(GO:0016540)
3.1 18.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
3.1 15.5 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
3.1 18.5 GO:0002934 desmosome organization(GO:0002934)
3.0 8.9 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
2.8 13.9 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
2.6 7.9 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
2.5 4.9 GO:0044111 development involved in symbiotic interaction(GO:0044111)
2.0 26.6 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
2.0 59.0 GO:0031581 hemidesmosome assembly(GO:0031581)
2.0 34.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
2.0 35.3 GO:0001765 membrane raft assembly(GO:0001765)
1.8 9.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
1.8 5.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.7 5.1 GO:0046521 sphingoid catabolic process(GO:0046521)
1.6 9.6 GO:0006741 NADP biosynthetic process(GO:0006741)
1.6 4.7 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
1.5 16.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
1.4 12.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
1.3 3.8 GO:1901656 glycoside transport(GO:1901656)
1.2 9.9 GO:0002036 regulation of L-glutamate transport(GO:0002036)
1.2 4.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
1.1 4.6 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.1 3.4 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
1.0 16.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
1.0 18.4 GO:0032060 bleb assembly(GO:0032060)
1.0 24.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
1.0 3.9 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
1.0 10.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
1.0 2.9 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.9 2.8 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.9 8.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.9 31.3 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.9 3.7 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.9 3.6 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.9 8.7 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.8 11.9 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.8 18.0 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.8 17.7 GO:0003334 keratinocyte development(GO:0003334)
0.8 10.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.8 13.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.8 6.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.7 4.4 GO:0030421 defecation(GO:0030421)
0.7 8.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.6 8.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.6 8.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.6 13.5 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.6 7.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.6 2.5 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.6 62.1 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.6 2.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.6 1.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.6 27.6 GO:0018149 peptide cross-linking(GO:0018149)
0.6 2.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.6 10.8 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.5 2.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.5 9.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.5 1.5 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.5 6.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.5 1.5 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.5 2.8 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.5 3.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.5 6.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 2.7 GO:0099563 modification of synaptic structure(GO:0099563)
0.4 1.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.4 6.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.4 6.6 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.4 8.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.4 1.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.4 2.6 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.4 1.1 GO:0035425 autocrine signaling(GO:0035425)
0.3 5.8 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.3 4.0 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 3.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 1.6 GO:0022614 membrane to membrane docking(GO:0022614) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.3 20.5 GO:0070527 platelet aggregation(GO:0070527)
0.3 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.3 8.9 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.3 2.7 GO:2000507 cap-dependent translational initiation(GO:0002191) positive regulation of energy homeostasis(GO:2000507)
0.3 4.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 3.1 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 10.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.3 2.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 3.3 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.3 6.6 GO:0042730 fibrinolysis(GO:0042730)
0.3 1.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.3 8.7 GO:0050819 negative regulation of coagulation(GO:0050819)
0.3 12.8 GO:0043486 histone exchange(GO:0043486)
0.3 1.0 GO:0033590 response to cobalamin(GO:0033590)
0.3 1.0 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2 11.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.2 11.2 GO:0030224 monocyte differentiation(GO:0030224)
0.2 1.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 1.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.2 6.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 15.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.2 2.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 1.5 GO:0035897 proteolysis in other organism(GO:0035897)
0.2 2.0 GO:0072513 semicircular canal morphogenesis(GO:0048752) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 3.0 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.2 15.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 1.4 GO:0035810 positive regulation of urine volume(GO:0035810)
0.2 1.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.2 23.1 GO:0002062 chondrocyte differentiation(GO:0002062)
0.2 4.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 4.1 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.2 2.3 GO:0044849 estrous cycle(GO:0044849)
0.2 25.9 GO:0030216 keratinocyte differentiation(GO:0030216)
0.2 6.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 10.7 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 1.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 3.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 7.6 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 0.5 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.1 3.4 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 1.6 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 2.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 4.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 9.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 2.0 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 3.9 GO:0045214 sarcomere organization(GO:0045214)
0.1 2.7 GO:0010842 retina layer formation(GO:0010842)
0.1 2.4 GO:0030728 ovulation(GO:0030728)
0.1 0.9 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.4 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 2.4 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 2.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 8.2 GO:0002576 platelet degranulation(GO:0002576)
0.1 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.5 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 4.2 GO:0048208 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 1.8 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 1.8 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.0 3.2 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 2.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.4 GO:0001660 fever generation(GO:0001660)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 2.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.0 GO:0072278 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric comma-shaped body morphogenesis(GO:0072278) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 2.4 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 1.3 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.8 GO:0009117 nucleotide metabolic process(GO:0009117)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.0 53.9 GO:0070435 Shc-EGFR complex(GO:0070435)
7.9 71.3 GO:0005638 lamin filament(GO:0005638)
7.6 22.9 GO:0005607 laminin-2 complex(GO:0005607)
5.3 42.3 GO:0005610 laminin-5 complex(GO:0005610)
4.2 21.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
4.0 28.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
3.6 18.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
3.0 26.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
2.9 53.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
2.8 13.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
2.1 18.5 GO:0030057 desmosome(GO:0030057)
2.0 24.2 GO:0016342 catenin complex(GO:0016342)
1.9 16.8 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
1.8 14.2 GO:0044294 dendritic growth cone(GO:0044294)
1.4 8.2 GO:0071817 MMXD complex(GO:0071817)
1.3 24.3 GO:0031089 platelet dense granule lumen(GO:0031089)
1.3 47.4 GO:0032420 stereocilium(GO:0032420)
1.2 10.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.2 4.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.1 58.1 GO:0001533 cornified envelope(GO:0001533)
1.1 25.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
1.1 10.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.1 6.3 GO:0030905 retromer, tubulation complex(GO:0030905)
1.0 3.0 GO:0033565 ESCRT-0 complex(GO:0033565)
1.0 3.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.9 11.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.9 16.4 GO:0036020 endolysosome membrane(GO:0036020)
0.9 3.6 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.9 26.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.9 13.6 GO:0097512 cardiac myofibril(GO:0097512)
0.8 8.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.8 5.4 GO:0097452 GAIT complex(GO:0097452)
0.7 7.6 GO:0016461 unconventional myosin complex(GO:0016461)
0.7 8.9 GO:0097470 ribbon synapse(GO:0097470)
0.6 12.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.6 8.1 GO:0097433 dense body(GO:0097433)
0.6 12.8 GO:0000812 Swr1 complex(GO:0000812)
0.5 7.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.5 1.6 GO:0044393 microspike(GO:0044393)
0.5 11.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.5 8.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.5 1.9 GO:0031673 H zone(GO:0031673)
0.4 4.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.4 37.0 GO:0005882 intermediate filament(GO:0005882)
0.4 2.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 1.0 GO:0071159 NF-kappaB complex(GO:0071159)
0.3 30.4 GO:0042734 presynaptic membrane(GO:0042734)
0.3 29.6 GO:0005604 basement membrane(GO:0005604)
0.3 4.5 GO:0008290 F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.3 7.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.3 4.0 GO:0044754 autolysosome(GO:0044754)
0.3 3.4 GO:0031209 SCAR complex(GO:0031209)
0.3 2.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 11.0 GO:0031430 M band(GO:0031430)
0.3 8.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 1.3 GO:0070522 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.2 4.7 GO:0043034 costamere(GO:0043034)
0.2 2.5 GO:0031045 dense core granule(GO:0031045)
0.2 9.9 GO:0002102 podosome(GO:0002102)
0.2 7.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 2.0 GO:0030056 hemidesmosome(GO:0030056)
0.2 3.5 GO:0031143 pseudopodium(GO:0031143)
0.2 15.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 1.6 GO:0030478 actin cap(GO:0030478)
0.1 3.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 2.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 8.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.0 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 2.4 GO:0005861 troponin complex(GO:0005861)
0.1 23.5 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 1.7 GO:0005922 connexon complex(GO:0005922)
0.1 9.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 5.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 2.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 5.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.1 GO:0042627 chylomicron(GO:0042627)
0.0 3.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.6 GO:0005844 polysome(GO:0005844)
0.0 4.8 GO:0030018 Z disc(GO:0030018)
0.0 4.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.3 GO:0005771 multivesicular body(GO:0005771)
0.0 2.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.1 GO:0005643 nuclear pore(GO:0005643)
0.0 1.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 3.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 7.8 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 1.7 GO:0005813 centrosome(GO:0005813)
0.0 2.0 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 53.9 GO:0048408 epidermal growth factor binding(GO:0048408)
6.5 26.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
5.2 15.5 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
4.9 29.2 GO:1990254 keratin filament binding(GO:1990254)
3.7 21.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
3.5 21.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
2.8 25.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
2.7 10.9 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
2.6 18.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
2.1 10.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
1.9 75.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.8 14.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.8 22.9 GO:0045294 alpha-catenin binding(GO:0045294)
1.7 16.8 GO:0051425 PTB domain binding(GO:0051425)
1.6 6.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.6 30.6 GO:0044548 S100 protein binding(GO:0044548)
1.6 9.6 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
1.4 5.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.3 7.9 GO:1903135 cupric ion binding(GO:1903135)
1.3 6.6 GO:0042289 MHC class II protein binding(GO:0042289)
1.3 3.9 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
1.3 6.3 GO:1990460 leptin receptor binding(GO:1990460)
1.2 8.7 GO:0004673 protein histidine kinase activity(GO:0004673)
1.1 13.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
1.0 31.5 GO:0005540 hyaluronic acid binding(GO:0005540)
1.0 16.9 GO:0045295 gamma-catenin binding(GO:0045295)
1.0 10.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.9 7.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.9 12.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.9 12.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.8 5.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.8 12.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.8 12.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.7 6.7 GO:0045545 syndecan binding(GO:0045545)
0.7 16.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.7 4.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.6 2.6 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.6 19.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 34.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.6 3.7 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.6 3.0 GO:0050436 microfibril binding(GO:0050436)
0.6 6.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.5 11.7 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.5 6.8 GO:0038132 neuregulin binding(GO:0038132)
0.5 4.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.5 8.3 GO:0008432 JUN kinase binding(GO:0008432)
0.5 3.6 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.5 32.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 17.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 7.6 GO:0048156 tau protein binding(GO:0048156)
0.4 10.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 9.7 GO:0070064 proline-rich region binding(GO:0070064)
0.4 1.5 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.4 3.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.3 18.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 1.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.5 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 2.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 6.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 18.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 4.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 2.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 30.0 GO:0044325 ion channel binding(GO:0044325)
0.2 172.5 GO:0005198 structural molecule activity(GO:0005198)
0.2 1.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 0.6 GO:0051373 FATZ binding(GO:0051373)
0.2 3.4 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 19.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.9 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 1.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 0.4 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.2 1.5 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.2 3.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 1.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 3.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 2.8 GO:0030275 LRR domain binding(GO:0030275)
0.2 2.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 1.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 2.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 3.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 5.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 3.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.9 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.6 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 2.3 GO:0071837 HMG box domain binding(GO:0071837)
0.1 9.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 4.0 GO:0005080 protein kinase C binding(GO:0005080)
0.1 11.8 GO:0002020 protease binding(GO:0002020)
0.1 13.2 GO:0008201 heparin binding(GO:0008201)
0.1 1.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 38.0 GO:0005525 GTP binding(GO:0005525)
0.1 3.8 GO:0051119 sugar transmembrane transporter activity(GO:0051119) carbohydrate derivative transporter activity(GO:1901505)
0.1 4.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 3.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.3 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 2.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 4.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 11.9 GO:0045296 cadherin binding(GO:0045296)
0.0 1.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 3.8 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.7 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.8 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0030228 low-density lipoprotein receptor activity(GO:0005041) lipoprotein particle receptor activity(GO:0030228)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 2.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.3 GO:0001047 core promoter binding(GO:0001047)
0.0 1.2 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.8 GO:0019838 growth factor binding(GO:0019838)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 67.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.4 44.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
1.4 39.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
1.4 48.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.1 70.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.9 63.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.9 29.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.8 35.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.8 67.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.7 38.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.6 15.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.6 35.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.5 11.7 PID ARF 3PATHWAY Arf1 pathway
0.5 26.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 18.7 PID RAS PATHWAY Regulation of Ras family activation
0.3 18.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 3.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 19.6 PID AURORA B PATHWAY Aurora B signaling
0.3 20.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 4.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 13.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 10.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 4.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 14.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 5.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 30.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.8 PID IL1 PATHWAY IL1-mediated signaling events
0.1 3.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 19.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 28.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 8.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 0.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.0 PID FOXO PATHWAY FoxO family signaling
0.0 2.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 53.9 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
1.9 26.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.8 3.6 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
1.5 18.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
1.5 28.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.1 20.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.0 51.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
1.0 73.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
1.0 26.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.9 16.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.8 62.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.8 24.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.7 16.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.7 61.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.6 23.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.6 10.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.6 15.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 1.5 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.5 19.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.5 38.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.5 8.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.4 6.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.4 8.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.4 1.1 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.3 7.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 8.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 23.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 9.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 2.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 3.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 5.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 9.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 3.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 9.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 15.5 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 2.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 4.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.8 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 6.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 10.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 4.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 12.2 REACTOME TRANSLATION Genes involved in Translation
0.0 1.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 3.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 2.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling