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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for FOSL2_SMARCC1
Z-value: 2.11
Motif logo
Transcription factors associated with FOSL2_SMARCC1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
FOSL2
|
ENSG00000075426.7 | FOS like 2, AP-1 transcription factor subunit |
|
SMARCC1
|
ENSG00000173473.6 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOSL2 | hg19_v2_chr2_+_28615669_28615733 | 0.24 | 3.4e-04 | Click! |
| SMARCC1 | hg19_v2_chr3_-_47823298_47823423 | 0.23 | 6.2e-04 | Click! |
Activity profile of FOSL2_SMARCC1 motif
Sorted Z-values of FOSL2_SMARCC1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_223889285 | 74.89 |
ENST00000433674.2
|
CAPN2
|
calpain 2, (m/II) large subunit |
| chr1_-_113247543 | 71.58 |
ENST00000414971.1
ENST00000534717.1 |
RHOC
|
ras homolog family member C |
| chr6_-_31704282 | 59.93 |
ENST00000375784.3
ENST00000375779.2 |
CLIC1
|
chloride intracellular channel 1 |
| chr22_+_23241661 | 45.39 |
ENST00000390322.2
|
IGLJ2
|
immunoglobulin lambda joining 2 |
| chr1_+_156096336 | 42.14 |
ENST00000504687.1
ENST00000473598.2 |
LMNA
|
lamin A/C |
| chr1_+_156084461 | 41.84 |
ENST00000347559.2
ENST00000361308.4 ENST00000368300.4 ENST00000368299.3 |
LMNA
|
lamin A/C |
| chr1_-_151965048 | 39.20 |
ENST00000368809.1
|
S100A10
|
S100 calcium binding protein A10 |
| chr2_+_89901292 | 34.61 |
ENST00000448155.2
|
IGKV1D-39
|
immunoglobulin kappa variable 1D-39 |
| chr1_+_156095951 | 33.25 |
ENST00000448611.2
ENST00000368297.1 |
LMNA
|
lamin A/C |
| chr2_+_90060377 | 33.18 |
ENST00000436451.2
|
IGKV6D-21
|
immunoglobulin kappa variable 6D-21 (non-functional) |
| chr11_-_64013288 | 32.90 |
ENST00000542235.1
|
PPP1R14B
|
protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| chr22_+_23077065 | 32.57 |
ENST00000390310.2
|
IGLV2-18
|
immunoglobulin lambda variable 2-18 |
| chr2_-_89459813 | 32.47 |
ENST00000390256.2
|
IGKV6-21
|
immunoglobulin kappa variable 6-21 (non-functional) |
| chr12_-_53343602 | 31.82 |
ENST00000546897.1
ENST00000552551.1 |
KRT8
|
keratin 8 |
| chr12_-_56122426 | 31.00 |
ENST00000551173.1
|
CD63
|
CD63 molecule |
| chr18_+_21452804 | 30.68 |
ENST00000269217.6
|
LAMA3
|
laminin, alpha 3 |
| chr7_+_73245193 | 28.97 |
ENST00000340958.2
|
CLDN4
|
claudin 4 |
| chr11_-_64013663 | 28.62 |
ENST00000392210.2
|
PPP1R14B
|
protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| chr3_-_81792780 | 28.61 |
ENST00000489715.1
|
GBE1
|
glucan (1,4-alpha-), branching enzyme 1 |
| chr5_+_138089100 | 27.94 |
ENST00000520339.1
ENST00000355078.5 ENST00000302763.7 ENST00000518910.1 |
CTNNA1
|
catenin (cadherin-associated protein), alpha 1, 102kDa |
| chr10_+_17270214 | 27.25 |
ENST00000544301.1
|
VIM
|
vimentin |
| chr2_-_89417335 | 26.97 |
ENST00000490686.1
|
IGKV1-17
|
immunoglobulin kappa variable 1-17 |
| chr2_-_89399845 | 26.40 |
ENST00000479981.1
|
IGKV1-16
|
immunoglobulin kappa variable 1-16 |
| chr11_-_65667997 | 26.20 |
ENST00000312562.2
ENST00000534222.1 |
FOSL1
|
FOS-like antigen 1 |
| chr15_-_60690163 | 25.99 |
ENST00000558998.1
ENST00000560165.1 ENST00000557986.1 ENST00000559780.1 ENST00000559467.1 ENST00000559956.1 ENST00000332680.4 ENST00000396024.3 ENST00000421017.2 ENST00000560466.1 ENST00000558132.1 ENST00000559113.1 ENST00000557906.1 ENST00000558558.1 ENST00000560468.1 ENST00000559370.1 ENST00000558169.1 ENST00000559725.1 ENST00000558985.1 ENST00000451270.2 |
ANXA2
|
annexin A2 |
| chr1_+_26606608 | 25.73 |
ENST00000319041.6
|
SH3BGRL3
|
SH3 domain binding glutamic acid-rich protein like 3 |
| chr11_-_65667884 | 25.11 |
ENST00000448083.2
ENST00000531493.1 ENST00000532401.1 |
FOSL1
|
FOS-like antigen 1 |
| chr2_+_90121477 | 24.21 |
ENST00000483379.1
|
IGKV1D-17
|
immunoglobulin kappa variable 1D-17 |
| chr5_+_135394840 | 23.98 |
ENST00000503087.1
|
TGFBI
|
transforming growth factor, beta-induced, 68kDa |
| chr7_+_116312411 | 23.93 |
ENST00000456159.1
ENST00000397752.3 ENST00000318493.6 |
MET
|
met proto-oncogene |
| chr6_-_30712313 | 23.83 |
ENST00000376377.2
ENST00000259874.5 |
IER3
|
immediate early response 3 |
| chr11_-_2950642 | 23.04 |
ENST00000314222.4
|
PHLDA2
|
pleckstrin homology-like domain, family A, member 2 |
| chr14_+_58711539 | 22.85 |
ENST00000216455.4
ENST00000412908.2 ENST00000557508.1 |
PSMA3
|
proteasome (prosome, macropain) subunit, alpha type, 3 |
| chr2_+_90139056 | 22.32 |
ENST00000492446.1
|
IGKV1D-16
|
immunoglobulin kappa variable 1D-16 |
| chr17_-_79481666 | 22.17 |
ENST00000575659.1
|
ACTG1
|
actin, gamma 1 |
| chr10_+_121410882 | 21.75 |
ENST00000369085.3
|
BAG3
|
BCL2-associated athanogene 3 |
| chr11_+_101983176 | 21.35 |
ENST00000524575.1
|
YAP1
|
Yes-associated protein 1 |
| chr1_-_153538011 | 21.18 |
ENST00000368707.4
|
S100A2
|
S100 calcium binding protein A2 |
| chrX_+_47441712 | 21.08 |
ENST00000218388.4
ENST00000377018.2 ENST00000456754.2 ENST00000377017.1 ENST00000441738.1 |
TIMP1
|
TIMP metallopeptidase inhibitor 1 |
| chrX_+_49028265 | 21.06 |
ENST00000376322.3
ENST00000376327.5 |
PLP2
|
proteolipid protein 2 (colonic epithelium-enriched) |
| chr7_+_55177416 | 20.67 |
ENST00000450046.1
ENST00000454757.2 |
EGFR
|
epidermal growth factor receptor |
| chr2_+_89998789 | 20.48 |
ENST00000453166.2
|
IGKV2D-28
|
immunoglobulin kappa variable 2D-28 |
| chr17_-_73150629 | 20.11 |
ENST00000356033.4
ENST00000405458.3 ENST00000409753.3 |
HN1
|
hematological and neurological expressed 1 |
| chr22_+_23134974 | 19.98 |
ENST00000390314.2
|
IGLV2-11
|
immunoglobulin lambda variable 2-11 |
| chr1_-_159894319 | 19.84 |
ENST00000320307.4
|
TAGLN2
|
transgelin 2 |
| chr16_-_69760409 | 19.77 |
ENST00000561500.1
ENST00000439109.2 ENST00000564043.1 ENST00000379046.2 ENST00000379047.3 |
NQO1
|
NAD(P)H dehydrogenase, quinone 1 |
| chr2_+_89999259 | 19.57 |
ENST00000558026.1
|
IGKV2D-28
|
immunoglobulin kappa variable 2D-28 |
| chr2_-_89521942 | 19.18 |
ENST00000482769.1
|
IGKV2-28
|
immunoglobulin kappa variable 2-28 |
| chr4_+_74606223 | 19.09 |
ENST00000307407.3
ENST00000401931.1 |
IL8
|
interleukin 8 |
| chr7_-_96339132 | 18.72 |
ENST00000413065.1
|
SHFM1
|
split hand/foot malformation (ectrodactyly) type 1 |
| chr1_+_27189631 | 18.69 |
ENST00000339276.4
|
SFN
|
stratifin |
| chr2_-_89340242 | 17.74 |
ENST00000480492.1
|
IGKV1-12
|
immunoglobulin kappa variable 1-12 |
| chr18_+_21452964 | 17.56 |
ENST00000587184.1
|
LAMA3
|
laminin, alpha 3 |
| chr2_-_89568263 | 17.10 |
ENST00000473726.1
|
IGKV1-33
|
immunoglobulin kappa variable 1-33 |
| chr2_+_89923550 | 17.10 |
ENST00000509129.1
|
IGKV1D-37
|
immunoglobulin kappa variable 1D-37 (non-functional) |
| chr17_+_35851570 | 17.03 |
ENST00000394386.1
|
DUSP14
|
dual specificity phosphatase 14 |
| chr15_+_67420441 | 16.81 |
ENST00000558894.1
|
SMAD3
|
SMAD family member 3 |
| chr1_-_152009460 | 16.59 |
ENST00000271638.2
|
S100A11
|
S100 calcium binding protein A11 |
| chr15_+_64428529 | 16.19 |
ENST00000560861.1
|
SNX1
|
sorting nexin 1 |
| chr3_-_149095652 | 16.16 |
ENST00000305366.3
|
TM4SF1
|
transmembrane 4 L six family member 1 |
| chr11_-_102668879 | 15.85 |
ENST00000315274.6
|
MMP1
|
matrix metallopeptidase 1 (interstitial collagenase) |
| chr2_+_89952792 | 15.58 |
ENST00000390265.2
|
IGKV1D-33
|
immunoglobulin kappa variable 1D-33 |
| chr12_+_13349650 | 15.28 |
ENST00000256951.5
ENST00000431267.2 ENST00000542474.1 ENST00000544053.1 |
EMP1
|
epithelial membrane protein 1 |
| chr2_+_90198535 | 15.08 |
ENST00000390276.2
|
IGKV1D-12
|
immunoglobulin kappa variable 1D-12 |
| chr5_+_72143988 | 14.70 |
ENST00000506351.2
|
TNPO1
|
transportin 1 |
| chr15_+_22892663 | 14.65 |
ENST00000313077.7
ENST00000561274.1 ENST00000560848.1 |
CYFIP1
|
cytoplasmic FMR1 interacting protein 1 |
| chr2_-_89619904 | 14.65 |
ENST00000498574.1
|
IGKV1-39
|
immunoglobulin kappa variable 1-39 (gene/pseudogene) |
| chr19_-_44174330 | 14.60 |
ENST00000340093.3
|
PLAUR
|
plasminogen activator, urokinase receptor |
| chr1_+_26605618 | 14.38 |
ENST00000270792.5
|
SH3BGRL3
|
SH3 domain binding glutamic acid-rich protein like 3 |
| chr19_+_36630855 | 14.14 |
ENST00000589146.1
|
CAPNS1
|
calpain, small subunit 1 |
| chr12_-_56122761 | 14.09 |
ENST00000552164.1
ENST00000420846.3 ENST00000257857.4 |
CD63
|
CD63 molecule |
| chr19_+_36630961 | 14.08 |
ENST00000587718.1
ENST00000592483.1 ENST00000590874.1 ENST00000588815.1 |
CAPNS1
|
calpain, small subunit 1 |
| chr5_+_150020214 | 13.84 |
ENST00000307662.4
|
SYNPO
|
synaptopodin |
| chr11_-_6341844 | 13.75 |
ENST00000303927.3
|
PRKCDBP
|
protein kinase C, delta binding protein |
| chr8_+_126442563 | 13.62 |
ENST00000311922.3
|
TRIB1
|
tribbles pseudokinase 1 |
| chr7_-_107643674 | 13.53 |
ENST00000222399.6
|
LAMB1
|
laminin, beta 1 |
| chr3_-_49395705 | 13.50 |
ENST00000419349.1
|
GPX1
|
glutathione peroxidase 1 |
| chrX_-_15511438 | 13.42 |
ENST00000380420.5
|
PIR
|
pirin (iron-binding nuclear protein) |
| chr6_+_83072923 | 13.37 |
ENST00000535040.1
|
TPBG
|
trophoblast glycoprotein |
| chr19_+_36630454 | 13.26 |
ENST00000246533.3
|
CAPNS1
|
calpain, small subunit 1 |
| chr4_+_169753156 | 13.11 |
ENST00000393726.3
ENST00000507735.1 |
PALLD
|
palladin, cytoskeletal associated protein |
| chr6_-_138428613 | 13.01 |
ENST00000421351.3
|
PERP
|
PERP, TP53 apoptosis effector |
| chr11_+_35198243 | 12.78 |
ENST00000528455.1
|
CD44
|
CD44 molecule (Indian blood group) |
| chr17_-_39942940 | 12.72 |
ENST00000310706.5
ENST00000393931.3 ENST00000424457.1 ENST00000591690.1 |
JUP
|
junction plakoglobin |
| chr2_-_85641162 | 12.69 |
ENST00000447219.2
ENST00000409670.1 ENST00000409724.1 |
CAPG
|
capping protein (actin filament), gelsolin-like |
| chr11_+_35198118 | 12.57 |
ENST00000525211.1
ENST00000526000.1 ENST00000279452.6 ENST00000527889.1 |
CD44
|
CD44 molecule (Indian blood group) |
| chr2_+_90192768 | 12.33 |
ENST00000390275.2
|
IGKV1D-13
|
immunoglobulin kappa variable 1D-13 |
| chr17_-_18161870 | 12.30 |
ENST00000579294.1
ENST00000545457.2 ENST00000379450.4 ENST00000578558.1 |
FLII
|
flightless I homolog (Drosophila) |
| chr1_-_24126023 | 12.27 |
ENST00000429356.1
|
GALE
|
UDP-galactose-4-epimerase |
| chr9_+_71819927 | 11.92 |
ENST00000535702.1
|
TJP2
|
tight junction protein 2 |
| chr22_+_23165153 | 11.69 |
ENST00000390317.2
|
IGLV2-8
|
immunoglobulin lambda variable 2-8 |
| chr18_+_3449695 | 11.68 |
ENST00000343820.5
|
TGIF1
|
TGFB-induced factor homeobox 1 |
| chr11_+_844406 | 11.58 |
ENST00000397404.1
|
TSPAN4
|
tetraspanin 4 |
| chr11_+_10326612 | 11.53 |
ENST00000534464.1
ENST00000530439.1 ENST00000524948.1 ENST00000528655.1 ENST00000526492.1 ENST00000525063.1 |
ADM
|
adrenomedullin |
| chr12_-_56120865 | 11.50 |
ENST00000548898.1
ENST00000552067.1 |
CD63
|
CD63 molecule |
| chr12_-_56120838 | 11.50 |
ENST00000548160.1
|
CD63
|
CD63 molecule |
| chr18_+_3449821 | 11.43 |
ENST00000407501.2
ENST00000405385.3 ENST00000546979.1 |
TGIF1
|
TGFB-induced factor homeobox 1 |
| chr9_+_71820057 | 11.40 |
ENST00000539225.1
|
TJP2
|
tight junction protein 2 |
| chr6_-_159239257 | 11.39 |
ENST00000337147.7
ENST00000392177.4 |
EZR
|
ezrin |
| chr11_+_844067 | 11.38 |
ENST00000397406.1
ENST00000409543.2 ENST00000525201.1 |
TSPAN4
|
tetraspanin 4 |
| chr11_+_394196 | 11.36 |
ENST00000331563.2
ENST00000531857.1 |
PKP3
|
plakophilin 3 |
| chr11_+_67351019 | 11.35 |
ENST00000398606.3
|
GSTP1
|
glutathione S-transferase pi 1 |
| chr3_+_30648066 | 11.27 |
ENST00000359013.4
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa) |
| chr3_-_32022733 | 11.23 |
ENST00000438237.2
ENST00000396556.2 |
OSBPL10
|
oxysterol binding protein-like 10 |
| chr12_+_53491220 | 11.02 |
ENST00000548547.1
ENST00000301464.3 |
IGFBP6
|
insulin-like growth factor binding protein 6 |
| chr15_+_41136586 | 10.79 |
ENST00000431806.1
|
SPINT1
|
serine peptidase inhibitor, Kunitz type 1 |
| chr17_+_75446819 | 10.76 |
ENST00000541152.2
ENST00000591704.1 |
SEPT9
|
septin 9 |
| chr22_+_22735135 | 10.75 |
ENST00000390297.2
|
IGLV1-44
|
immunoglobulin lambda variable 1-44 |
| chr6_+_44194762 | 10.71 |
ENST00000371708.1
|
SLC29A1
|
solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| chr1_+_150480551 | 10.68 |
ENST00000369049.4
ENST00000369047.4 |
ECM1
|
extracellular matrix protein 1 |
| chr7_-_96339167 | 10.64 |
ENST00000444799.1
ENST00000417009.1 ENST00000248566.2 |
SHFM1
|
split hand/foot malformation (ectrodactyly) type 1 |
| chr17_-_73781567 | 10.59 |
ENST00000586607.1
|
H3F3B
|
H3 histone, family 3B (H3.3B) |
| chr5_+_73980965 | 10.50 |
ENST00000261416.7
|
HEXB
|
hexosaminidase B (beta polypeptide) |
| chr17_+_49230897 | 10.47 |
ENST00000393196.3
ENST00000336097.3 ENST00000480143.1 ENST00000511355.1 ENST00000013034.3 ENST00000393198.3 ENST00000608447.1 ENST00000393193.2 ENST00000376392.6 ENST00000555572.1 |
NME1
NME1-NME2
NME2
|
NME/NM23 nucleoside diphosphate kinase 1 NME1-NME2 readthrough NME/NM23 nucleoside diphosphate kinase 2 |
| chr11_+_46402297 | 10.29 |
ENST00000405308.2
|
MDK
|
midkine (neurite growth-promoting factor 2) |
| chr3_+_30647994 | 10.18 |
ENST00000295754.5
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa) |
| chr22_+_23089870 | 10.00 |
ENST00000390311.2
|
IGLV3-16
|
immunoglobulin lambda variable 3-16 |
| chr1_-_154943002 | 9.82 |
ENST00000606391.1
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1 |
| chr1_-_154943212 | 9.80 |
ENST00000368445.5
ENST00000448116.2 ENST00000368449.4 |
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1 |
| chr1_+_150480576 | 9.65 |
ENST00000346569.6
|
ECM1
|
extracellular matrix protein 1 |
| chr5_-_176923803 | 9.58 |
ENST00000506161.1
|
PDLIM7
|
PDZ and LIM domain 7 (enigma) |
| chr20_+_44637526 | 9.55 |
ENST00000372330.3
|
MMP9
|
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
| chr8_-_141774467 | 9.54 |
ENST00000520151.1
ENST00000519024.1 ENST00000519465.1 |
PTK2
|
protein tyrosine kinase 2 |
| chr11_-_66103867 | 9.50 |
ENST00000424433.2
|
RIN1
|
Ras and Rab interactor 1 |
| chr2_+_90108504 | 9.49 |
ENST00000390271.2
|
IGKV6D-41
|
immunoglobulin kappa variable 6D-41 (non-functional) |
| chrX_-_10851762 | 9.18 |
ENST00000380785.1
ENST00000380787.1 |
MID1
|
midline 1 (Opitz/BBB syndrome) |
| chr11_+_67351213 | 9.12 |
ENST00000398603.1
|
GSTP1
|
glutathione S-transferase pi 1 |
| chr22_+_22707260 | 9.10 |
ENST00000390293.1
|
IGLV5-48
|
immunoglobulin lambda variable 5-48 (non-functional) |
| chr2_-_89597542 | 9.08 |
ENST00000465170.1
|
IGKV1-37
|
immunoglobulin kappa variable 1-37 (non-functional) |
| chr3_+_184038073 | 9.01 |
ENST00000428387.1
ENST00000434061.2 |
EIF4G1
|
eukaryotic translation initiation factor 4 gamma, 1 |
| chr12_+_64798095 | 8.98 |
ENST00000332707.5
|
XPOT
|
exportin, tRNA |
| chr3_+_127771212 | 8.97 |
ENST00000243253.3
ENST00000481210.1 |
SEC61A1
|
Sec61 alpha 1 subunit (S. cerevisiae) |
| chr22_+_23046750 | 8.95 |
ENST00000390307.2
|
IGLV3-22
|
immunoglobulin lambda variable 3-22 (gene/pseudogene) |
| chr6_-_84140757 | 8.92 |
ENST00000541327.1
ENST00000369705.3 ENST00000543031.1 |
ME1
|
malic enzyme 1, NADP(+)-dependent, cytosolic |
| chr15_+_41136216 | 8.92 |
ENST00000562057.1
ENST00000344051.4 |
SPINT1
|
serine peptidase inhibitor, Kunitz type 1 |
| chr20_+_33759854 | 8.81 |
ENST00000216968.4
|
PROCR
|
protein C receptor, endothelial |
| chr5_-_176923846 | 8.81 |
ENST00000506537.1
|
PDLIM7
|
PDZ and LIM domain 7 (enigma) |
| chr3_+_5020801 | 8.74 |
ENST00000256495.3
|
BHLHE40
|
basic helix-loop-helix family, member e40 |
| chr3_+_184037466 | 8.60 |
ENST00000441154.1
|
EIF4G1
|
eukaryotic translation initiation factor 4 gamma, 1 |
| chr3_+_100428316 | 8.48 |
ENST00000479672.1
ENST00000476228.1 ENST00000463568.1 |
TFG
|
TRK-fused gene |
| chr9_-_35685452 | 8.37 |
ENST00000607559.1
|
TPM2
|
tropomyosin 2 (beta) |
| chr19_-_44174305 | 8.34 |
ENST00000601723.1
ENST00000339082.3 |
PLAUR
|
plasminogen activator, urokinase receptor |
| chr22_+_23029188 | 8.22 |
ENST00000390305.2
|
IGLV3-25
|
immunoglobulin lambda variable 3-25 |
| chr7_+_129932974 | 8.08 |
ENST00000445470.2
ENST00000222482.4 ENST00000492072.1 ENST00000473956.1 ENST00000493259.1 ENST00000486598.1 |
CPA4
|
carboxypeptidase A4 |
| chr21_+_10862622 | 7.99 |
ENST00000302092.5
ENST00000559480.1 |
IGHV1OR21-1
|
immunoglobulin heavy variable 1/OR21-1 (non-functional) |
| chr19_+_49377575 | 7.97 |
ENST00000600406.1
|
PPP1R15A
|
protein phosphatase 1, regulatory subunit 15A |
| chr1_-_150208363 | 7.74 |
ENST00000436748.2
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr10_+_75670862 | 7.74 |
ENST00000446342.1
ENST00000372764.3 ENST00000372762.4 |
PLAU
|
plasminogen activator, urokinase |
| chr1_-_109968973 | 7.73 |
ENST00000271308.4
ENST00000538610.1 |
PSMA5
|
proteasome (prosome, macropain) subunit, alpha type, 5 |
| chr3_+_100428268 | 7.72 |
ENST00000240851.4
|
TFG
|
TRK-fused gene |
| chr17_-_39743139 | 7.67 |
ENST00000167586.6
|
KRT14
|
keratin 14 |
| chr7_+_48128194 | 7.66 |
ENST00000416681.1
ENST00000331803.4 ENST00000432131.1 |
UPP1
|
uridine phosphorylase 1 |
| chr15_-_20170354 | 7.54 |
ENST00000338912.5
|
IGHV1OR15-9
|
immunoglobulin heavy variable 1/OR15-9 (non-functional) |
| chr3_+_100428188 | 7.50 |
ENST00000418917.2
ENST00000490574.1 |
TFG
|
TRK-fused gene |
| chr2_+_89890533 | 7.50 |
ENST00000429992.2
|
IGKV2D-40
|
immunoglobulin kappa variable 2D-40 |
| chr7_+_48128316 | 7.31 |
ENST00000341253.4
|
UPP1
|
uridine phosphorylase 1 |
| chr10_+_88854926 | 7.18 |
ENST00000298784.1
ENST00000298786.4 |
FAM35A
|
family with sequence similarity 35, member A |
| chr12_+_123237321 | 7.17 |
ENST00000280557.6
ENST00000455982.2 |
DENR
|
density-regulated protein |
| chr3_+_69134080 | 7.13 |
ENST00000273258.3
|
ARL6IP5
|
ADP-ribosylation-like factor 6 interacting protein 5 |
| chr22_+_23063100 | 7.04 |
ENST00000390309.2
|
IGLV3-19
|
immunoglobulin lambda variable 3-19 |
| chr1_-_209824643 | 7.03 |
ENST00000391911.1
ENST00000415782.1 |
LAMB3
|
laminin, beta 3 |
| chr7_-_55606346 | 6.98 |
ENST00000545390.1
|
VOPP1
|
vesicular, overexpressed in cancer, prosurvival protein 1 |
| chrX_-_129244655 | 6.96 |
ENST00000335997.7
|
ELF4
|
E74-like factor 4 (ets domain transcription factor) |
| chr13_+_102142296 | 6.90 |
ENST00000376162.3
|
ITGBL1
|
integrin, beta-like 1 (with EGF-like repeat domains) |
| chr22_+_23154239 | 6.78 |
ENST00000390315.2
|
IGLV3-10
|
immunoglobulin lambda variable 3-10 |
| chr8_-_82395461 | 6.71 |
ENST00000256104.4
|
FABP4
|
fatty acid binding protein 4, adipocyte |
| chr17_-_7590745 | 6.68 |
ENST00000514944.1
ENST00000503591.1 ENST00000455263.2 ENST00000420246.2 ENST00000445888.2 ENST00000509690.1 ENST00000604348.1 ENST00000269305.4 |
TP53
|
tumor protein p53 |
| chr6_+_63921351 | 6.67 |
ENST00000370659.1
|
FKBP1C
|
FK506 binding protein 1C |
| chr3_+_187930719 | 6.63 |
ENST00000312675.4
|
LPP
|
LIM domain containing preferred translocation partner in lipoma |
| chr22_+_22712087 | 6.59 |
ENST00000390294.2
|
IGLV1-47
|
immunoglobulin lambda variable 1-47 |
| chr6_+_63921399 | 6.59 |
ENST00000356170.3
|
FKBP1C
|
FK506 binding protein 1C |
| chr22_-_30642782 | 6.56 |
ENST00000249075.3
|
LIF
|
leukemia inhibitory factor |
| chr2_+_201171064 | 6.56 |
ENST00000451764.2
|
SPATS2L
|
spermatogenesis associated, serine-rich 2-like |
| chr10_-_98346801 | 6.51 |
ENST00000371142.4
|
TM9SF3
|
transmembrane 9 superfamily member 3 |
| chr1_-_150208291 | 6.44 |
ENST00000533654.1
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chrX_-_129244454 | 6.38 |
ENST00000308167.5
|
ELF4
|
E74-like factor 4 (ets domain transcription factor) |
| chr1_-_150208412 | 6.37 |
ENST00000532744.1
ENST00000369114.5 ENST00000369115.2 ENST00000369116.4 |
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr17_+_21191341 | 6.37 |
ENST00000526076.2
ENST00000361818.5 ENST00000316920.6 |
MAP2K3
|
mitogen-activated protein kinase kinase 3 |
| chr2_-_219134822 | 6.29 |
ENST00000444053.1
ENST00000248450.4 |
AAMP
|
angio-associated, migratory cell protein |
| chr3_-_149293990 | 6.23 |
ENST00000472417.1
|
WWTR1
|
WW domain containing transcription regulator 1 |
| chr5_-_138534071 | 6.23 |
ENST00000394817.2
|
SIL1
|
SIL1 nucleotide exchange factor |
| chr7_+_99006232 | 6.22 |
ENST00000403633.2
|
BUD31
|
BUD31 homolog (S. cerevisiae) |
| chr17_+_7123125 | 6.17 |
ENST00000356839.5
ENST00000583312.1 ENST00000350303.5 |
ACADVL
|
acyl-CoA dehydrogenase, very long chain |
| chr7_+_112063192 | 6.15 |
ENST00000005558.4
|
IFRD1
|
interferon-related developmental regulator 1 |
| chr14_+_103801140 | 6.13 |
ENST00000561325.1
ENST00000392715.2 ENST00000559130.1 ENST00000559532.1 ENST00000558506.1 |
EIF5
|
eukaryotic translation initiation factor 5 |
| chr3_-_151034734 | 6.09 |
ENST00000260843.4
|
GPR87
|
G protein-coupled receptor 87 |
| chr16_+_30077055 | 6.01 |
ENST00000564595.2
ENST00000569798.1 |
ALDOA
|
aldolase A, fructose-bisphosphate |
| chr11_-_62323702 | 5.96 |
ENST00000530285.1
|
AHNAK
|
AHNAK nucleoprotein |
| chr6_-_43027105 | 5.83 |
ENST00000230413.5
ENST00000487429.1 ENST00000489623.1 ENST00000468957.1 |
MRPL2
|
mitochondrial ribosomal protein L2 |
| chr5_+_179247759 | 5.75 |
ENST00000389805.4
ENST00000504627.1 ENST00000402874.3 ENST00000510187.1 |
SQSTM1
|
sequestosome 1 |
| chr1_-_150208498 | 5.75 |
ENST00000314136.8
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr2_+_201981527 | 5.74 |
ENST00000441224.1
|
CFLAR
|
CASP8 and FADD-like apoptosis regulator |
| chr2_+_90248739 | 5.73 |
ENST00000468879.1
|
IGKV1D-43
|
immunoglobulin kappa variable 1D-43 |
| chr1_+_155107820 | 5.72 |
ENST00000484157.1
|
SLC50A1
|
solute carrier family 50 (sugar efflux transporter), member 1 |
| chr7_+_94023873 | 5.72 |
ENST00000297268.6
|
COL1A2
|
collagen, type I, alpha 2 |
| chr1_-_27816641 | 5.67 |
ENST00000430629.2
|
WASF2
|
WAS protein family, member 2 |
| chr3_+_69134124 | 5.60 |
ENST00000478935.1
|
ARL6IP5
|
ADP-ribosylation-like factor 6 interacting protein 5 |
| chr6_-_38670897 | 5.59 |
ENST00000373365.4
|
GLO1
|
glyoxalase I |
| chr11_-_65430251 | 5.54 |
ENST00000534283.1
ENST00000527749.1 ENST00000533187.1 ENST00000525693.1 ENST00000534558.1 ENST00000532879.1 ENST00000532999.1 |
RELA
|
v-rel avian reticuloendotheliosis viral oncogene homolog A |
| chr16_+_30751953 | 5.54 |
ENST00000483578.1
|
RP11-2C24.4
|
RP11-2C24.4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOSL2_SMARCC1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 23.4 | 117.2 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 11.9 | 71.6 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 9.3 | 27.9 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 8.7 | 26.0 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) |
| 8.6 | 51.3 | GO:0007296 | vitellogenesis(GO:0007296) |
| 7.1 | 21.4 | GO:0002661 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
| 6.9 | 20.7 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
| 5.7 | 22.9 | GO:0038195 | urokinase plasminogen activator signaling pathway(GO:0038195) |
| 5.3 | 26.4 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 5.2 | 68.1 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 5.1 | 20.5 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 4.8 | 24.1 | GO:0002159 | desmosome assembly(GO:0002159) |
| 4.8 | 23.9 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 4.5 | 13.6 | GO:0045658 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 3.7 | 15.0 | GO:0006218 | uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108) |
| 3.7 | 18.7 | GO:0010481 | epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) |
| 3.7 | 14.7 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
| 3.4 | 13.5 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 3.2 | 25.3 | GO:1900625 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 3.1 | 15.7 | GO:1902459 | positive regulation of stem cell population maintenance(GO:1902459) |
| 2.8 | 5.6 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 2.7 | 8.0 | GO:1902310 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 2.6 | 21.1 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 2.6 | 7.7 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 2.5 | 73.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 2.5 | 50.2 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 2.4 | 7.3 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
| 2.4 | 41.2 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
| 2.4 | 7.2 | GO:0002188 | translation reinitiation(GO:0002188) |
| 2.4 | 9.6 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
| 2.4 | 2.4 | GO:0060559 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) |
| 2.3 | 23.3 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 2.3 | 25.2 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 2.3 | 11.4 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896) |
| 2.3 | 31.8 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
| 2.2 | 4.5 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 2.2 | 6.7 | GO:0051097 | negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252) |
| 2.2 | 13.3 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 2.2 | 314.3 | GO:0030449 | regulation of complement activation(GO:0030449) |
| 2.2 | 39.2 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 2.2 | 13.0 | GO:0002934 | desmosome organization(GO:0002934) |
| 2.1 | 10.7 | GO:0015862 | uridine transport(GO:0015862) |
| 2.1 | 10.5 | GO:0007619 | courtship behavior(GO:0007619) |
| 2.1 | 6.3 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 2.1 | 6.2 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 2.0 | 17.6 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 1.9 | 13.5 | GO:0018158 | response to selenium ion(GO:0010269) protein oxidation(GO:0018158) |
| 1.9 | 5.7 | GO:1901656 | glycoside transport(GO:1901656) |
| 1.8 | 9.0 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 1.7 | 22.7 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 1.7 | 13.8 | GO:0099563 | modification of synaptic structure(GO:0099563) |
| 1.7 | 10.3 | GO:0030421 | defecation(GO:0030421) |
| 1.7 | 26.5 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
| 1.6 | 1.6 | GO:0099552 | trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) |
| 1.6 | 12.7 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
| 1.6 | 6.3 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 1.5 | 8.9 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 1.4 | 4.3 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 1.4 | 5.5 | GO:0033590 | response to cobalamin(GO:0033590) |
| 1.4 | 2.7 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
| 1.4 | 4.1 | GO:2000364 | response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366) |
| 1.3 | 5.3 | GO:0097325 | melanocyte proliferation(GO:0097325) |
| 1.3 | 19.2 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 1.3 | 6.3 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 1.2 | 4.9 | GO:0032690 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
| 1.2 | 202.8 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 1.2 | 6.0 | GO:0071874 | response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874) |
| 1.2 | 4.8 | GO:0034141 | Toll signaling pathway(GO:0008063) positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) |
| 1.2 | 4.7 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 1.2 | 10.5 | GO:0018202 | peptidyl-histidine modification(GO:0018202) |
| 1.2 | 16.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 1.1 | 3.4 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 1.1 | 9.5 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 1.0 | 6.2 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 1.0 | 1.0 | GO:0034139 | regulation of toll-like receptor 3 signaling pathway(GO:0034139) |
| 1.0 | 4.1 | GO:0044861 | protein localization to plasma membrane raft(GO:0044860) protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288) |
| 1.0 | 9.9 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 1.0 | 14.7 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 1.0 | 9.8 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 1.0 | 4.9 | GO:0060356 | leucine import(GO:0060356) |
| 1.0 | 21.1 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 1.0 | 3.8 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 1.0 | 3.8 | GO:0019087 | transformation of host cell by virus(GO:0019087) |
| 0.9 | 12.3 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.9 | 9.4 | GO:1903943 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.9 | 6.4 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.9 | 3.6 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
| 0.9 | 6.2 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
| 0.9 | 5.3 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.9 | 3.5 | GO:1904378 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.9 | 2.6 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.9 | 80.7 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.9 | 20.8 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.9 | 13.9 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.8 | 15.3 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.8 | 3.3 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
| 0.8 | 5.5 | GO:1904849 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.8 | 6.2 | GO:0046322 | negative regulation of fatty acid oxidation(GO:0046322) |
| 0.8 | 16.1 | GO:0032461 | positive regulation of protein oligomerization(GO:0032461) |
| 0.7 | 6.7 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.7 | 68.6 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 0.7 | 12.3 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.7 | 2.9 | GO:0000023 | maltose metabolic process(GO:0000023) diaphragm contraction(GO:0002086) |
| 0.7 | 5.7 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 0.7 | 9.2 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.7 | 13.5 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.7 | 1.3 | GO:0023021 | termination of signal transduction(GO:0023021) |
| 0.7 | 2.0 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.6 | 30.1 | GO:0043486 | histone exchange(GO:0043486) |
| 0.6 | 19.6 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 0.6 | 1.8 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.6 | 9.1 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 0.6 | 3.4 | GO:0072719 | cellular response to cisplatin(GO:0072719) |
| 0.6 | 5.0 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.5 | 25.4 | GO:0030834 | regulation of actin filament depolymerization(GO:0030834) |
| 0.5 | 1.5 | GO:2000391 | positive regulation of neutrophil extravasation(GO:2000391) |
| 0.5 | 2.0 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.5 | 8.4 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.5 | 11.2 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.5 | 5.7 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.5 | 1.9 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.4 | 7.4 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.4 | 37.8 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.4 | 2.3 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.4 | 0.8 | GO:0032970 | regulation of actin filament-based process(GO:0032970) |
| 0.4 | 1.9 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.4 | 5.7 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.4 | 5.1 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.4 | 4.7 | GO:1904707 | positive regulation of vascular smooth muscle cell proliferation(GO:1904707) |
| 0.4 | 12.6 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.3 | 8.7 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.3 | 2.5 | GO:2000147 | positive regulation of cellular component movement(GO:0051272) positive regulation of cell motility(GO:2000147) |
| 0.3 | 20.8 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.3 | 0.9 | GO:0015680 | intracellular copper ion transport(GO:0015680) |
| 0.3 | 4.5 | GO:0043473 | pigmentation(GO:0043473) |
| 0.3 | 0.9 | GO:0002923 | regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.3 | 9.4 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.3 | 6.8 | GO:0072673 | lamellipodium morphogenesis(GO:0072673) |
| 0.3 | 11.8 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.3 | 13.3 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.3 | 1.6 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.3 | 16.6 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.3 | 22.9 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.3 | 1.1 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.2 | 10.6 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.2 | 1.0 | GO:0031099 | regeneration(GO:0031099) |
| 0.2 | 3.3 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.2 | 1.9 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.2 | 1.1 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 0.2 | 2.6 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.2 | 2.8 | GO:1901072 | glucosamine-containing compound catabolic process(GO:1901072) |
| 0.2 | 4.9 | GO:1902284 | axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284) |
| 0.2 | 1.3 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
| 0.2 | 14.2 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.2 | 1.4 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.2 | 1.2 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.2 | 19.0 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.2 | 1.1 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.2 | 0.9 | GO:0051036 | regulation of endosome size(GO:0051036) |
| 0.2 | 2.1 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.2 | 9.0 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.2 | 0.4 | GO:1903660 | negative regulation of complement-dependent cytotoxicity(GO:1903660) |
| 0.2 | 2.6 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.2 | 1.5 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.2 | 3.4 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
| 0.2 | 1.6 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.2 | 0.2 | GO:1903659 | regulation of complement-dependent cytotoxicity(GO:1903659) |
| 0.2 | 0.7 | GO:0051043 | regulation of membrane protein ectodomain proteolysis(GO:0051043) |
| 0.2 | 5.3 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.2 | 1.2 | GO:0010626 | regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010) |
| 0.2 | 0.8 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.2 | 6.6 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
| 0.2 | 6.1 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.2 | 1.1 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.2 | 6.9 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.1 | 0.6 | GO:0038089 | positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089) |
| 0.1 | 2.8 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.1 | 6.1 | GO:0010595 | positive regulation of endothelial cell migration(GO:0010595) |
| 0.1 | 6.3 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.1 | 0.4 | GO:0042938 | dipeptide transport(GO:0042938) |
| 0.1 | 0.7 | GO:1902172 | keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) |
| 0.1 | 0.8 | GO:1901379 | regulation of potassium ion transport(GO:0043266) regulation of potassium ion transmembrane transport(GO:1901379) |
| 0.1 | 12.9 | GO:0043542 | endothelial cell migration(GO:0043542) |
| 0.1 | 2.9 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.1 | 1.9 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 2.6 | GO:0030728 | ovulation(GO:0030728) |
| 0.1 | 1.6 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.1 | 5.4 | GO:0042058 | regulation of epidermal growth factor receptor signaling pathway(GO:0042058) |
| 0.1 | 11.3 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.1 | 0.2 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 0.1 | 3.1 | GO:0017004 | cytochrome complex assembly(GO:0017004) |
| 0.1 | 3.6 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.1 | 3.3 | GO:0006457 | protein folding(GO:0006457) |
| 0.1 | 9.8 | GO:0006302 | double-strand break repair(GO:0006302) |
| 0.1 | 1.8 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.1 | 2.2 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.1 | 1.8 | GO:0006959 | humoral immune response(GO:0006959) |
| 0.1 | 6.6 | GO:0006695 | cholesterol biosynthetic process(GO:0006695) |
| 0.1 | 5.8 | GO:0070126 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 0.1 | 0.3 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.1 | 0.3 | GO:2001223 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) negative regulation of neuron migration(GO:2001223) |
| 0.1 | 6.1 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 2.9 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.1 | 11.1 | GO:2001020 | regulation of response to DNA damage stimulus(GO:2001020) |
| 0.1 | 1.5 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.1 | 3.9 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 0.1 | 2.1 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 2.1 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 0.1 | GO:0060763 | estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) mammary duct terminal end bud growth(GO:0060763) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
| 0.1 | 1.6 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.1 | 5.0 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.1 | 2.8 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.1 | 1.4 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.0 | 0.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.0 | 0.3 | GO:0006591 | ornithine metabolic process(GO:0006591) positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.0 | 2.9 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 6.5 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 4.0 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.0 | 0.2 | GO:0098881 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.0 | 3.6 | GO:0043462 | regulation of ATPase activity(GO:0043462) |
| 0.0 | 0.2 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.0 | 1.5 | GO:1902403 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403) |
| 0.0 | 0.7 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.0 | 0.2 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 0.0 | 0.3 | GO:0030890 | positive regulation of B cell proliferation(GO:0030890) |
| 0.0 | 1.2 | GO:0006414 | translational elongation(GO:0006414) |
| 0.0 | 0.0 | GO:0072069 | DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240) |
| 0.0 | 0.6 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 0.6 | GO:0008630 | intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630) |
| 0.0 | 1.5 | GO:0030216 | keratinocyte differentiation(GO:0030216) |
| 0.0 | 0.8 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 13.0 | 117.2 | GO:0005638 | lamin filament(GO:0005638) |
| 7.4 | 88.8 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 6.9 | 55.3 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 6.8 | 20.5 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
| 6.5 | 19.6 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 5.2 | 26.0 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 5.1 | 15.4 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 4.3 | 21.4 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 3.8 | 11.4 | GO:0044393 | microspike(GO:0044393) |
| 3.6 | 25.3 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 3.4 | 40.7 | GO:0005915 | zonula adherens(GO:0005915) |
| 3.3 | 26.4 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 2.7 | 16.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 2.6 | 28.3 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 2.5 | 30.6 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 2.4 | 21.4 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 2.2 | 40.3 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 2.0 | 72.2 | GO:0032420 | stereocilium(GO:0032420) |
| 2.0 | 62.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 1.8 | 5.5 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 1.8 | 14.7 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 1.7 | 22.2 | GO:0097433 | dense body(GO:0097433) |
| 1.5 | 7.3 | GO:0032449 | CBM complex(GO:0032449) |
| 1.4 | 30.1 | GO:0000812 | Swr1 complex(GO:0000812) |
| 1.3 | 13.5 | GO:0097413 | Lewy body(GO:0097413) |
| 1.1 | 20.0 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 1.1 | 11.0 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 1.0 | 21.1 | GO:0031105 | septin complex(GO:0031105) |
| 0.9 | 27.8 | GO:0030057 | desmosome(GO:0030057) |
| 0.9 | 13.4 | GO:0090543 | Flemming body(GO:0090543) |
| 0.9 | 195.9 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.9 | 23.7 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.9 | 6.0 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.8 | 3.3 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.8 | 3.3 | GO:1990462 | omegasome(GO:1990462) |
| 0.8 | 17.6 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.7 | 5.5 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.6 | 9.1 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.6 | 5.0 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.5 | 1.6 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.5 | 5.1 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.5 | 10.7 | GO:0098644 | complex of collagen trimers(GO:0098644) |
| 0.5 | 8.0 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.5 | 7.7 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.4 | 8.9 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 0.4 | 8.4 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.4 | 5.7 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.4 | 34.7 | GO:0005604 | basement membrane(GO:0005604) |
| 0.4 | 7.5 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.4 | 43.8 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.4 | 5.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.4 | 38.4 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.4 | 5.1 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.4 | 5.7 | GO:0044754 | autolysosome(GO:0044754) |
| 0.4 | 1.1 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.4 | 35.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.3 | 9.0 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.3 | 14.3 | GO:0002102 | podosome(GO:0002102) |
| 0.3 | 1.6 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.3 | 4.2 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 0.3 | 1.3 | GO:0030678 | mitochondrial ribonuclease P complex(GO:0030678) |
| 0.2 | 11.7 | GO:0016235 | aggresome(GO:0016235) |
| 0.2 | 24.2 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.2 | 0.6 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.2 | 1.1 | GO:0030891 | VCB complex(GO:0030891) |
| 0.2 | 5.1 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.2 | 4.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.2 | 6.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.2 | 2.5 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.2 | 4.1 | GO:0043034 | costamere(GO:0043034) |
| 0.2 | 2.0 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.2 | 13.2 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.2 | 36.8 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.2 | 4.9 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.2 | 9.2 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.2 | 17.7 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.2 | 71.5 | GO:0030055 | cell-substrate junction(GO:0030055) |
| 0.1 | 5.8 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.1 | 9.0 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 3.5 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 10.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 177.0 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 3.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 6.7 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.1 | 1.2 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 6.2 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.1 | 11.4 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.1 | 26.1 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.1 | 9.0 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 13.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.1 | 1.9 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 3.5 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 3.4 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.1 | 5.1 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 186.9 | GO:0070062 | extracellular exosome(GO:0070062) |
| 0.1 | 0.6 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.1 | 1.2 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 6.0 | GO:0030018 | Z disc(GO:0030018) |
| 0.1 | 2.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 2.9 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 7.2 | GO:0005840 | ribosome(GO:0005840) |
| 0.1 | 9.0 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 4.9 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.4 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 1.4 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 1.2 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 2.3 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.8 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 1.3 | GO:0016605 | PML body(GO:0016605) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.6 | 22.9 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
| 6.2 | 18.7 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 5.8 | 34.9 | GO:1990254 | keratin filament binding(GO:1990254) |
| 5.8 | 40.3 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 5.4 | 21.4 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 5.3 | 26.4 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 4.3 | 26.0 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 4.1 | 20.5 | GO:0070026 | nitric oxide binding(GO:0070026) |
| 4.1 | 12.3 | GO:0003974 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 3.9 | 11.7 | GO:0036317 | tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260) |
| 3.7 | 15.0 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 3.4 | 20.3 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 3.2 | 16.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 2.4 | 33.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 2.4 | 92.7 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 2.3 | 6.9 | GO:0004362 | glutathione-disulfide reductase activity(GO:0004362) |
| 2.3 | 531.6 | GO:0003823 | antigen binding(GO:0003823) |
| 2.2 | 19.5 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 2.1 | 6.3 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 2.0 | 4.1 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 1.9 | 33.9 | GO:0044548 | S100 protein binding(GO:0044548) |
| 1.8 | 14.7 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 1.8 | 21.7 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 1.7 | 8.7 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 1.6 | 4.9 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 1.6 | 27.9 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 1.6 | 21.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 1.5 | 6.2 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 1.5 | 6.1 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 1.5 | 4.6 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 1.5 | 81.2 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 1.5 | 10.5 | GO:0004673 | protein histidine kinase activity(GO:0004673) |
| 1.5 | 8.9 | GO:0008948 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948) |
| 1.3 | 10.5 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 1.2 | 59.4 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 1.2 | 4.7 | GO:1904408 | dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408) |
| 1.2 | 3.5 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 1.2 | 34.8 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 1.2 | 17.3 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 1.1 | 8.0 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 1.1 | 17.0 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 1.1 | 3.4 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 1.1 | 9.0 | GO:0043022 | ribosome binding(GO:0043022) |
| 1.1 | 5.5 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 1.1 | 11.0 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 1.1 | 4.3 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 1.0 | 1.0 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 1.0 | 4.9 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 1.0 | 8.7 | GO:0043426 | MRF binding(GO:0043426) |
| 1.0 | 23.1 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 1.0 | 2.9 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 1.0 | 3.8 | GO:0033906 | protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906) |
| 0.9 | 2.7 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.9 | 13.5 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.9 | 24.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.8 | 13.6 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.8 | 3.8 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.8 | 8.4 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.7 | 6.7 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.7 | 1.4 | GO:0005171 | hepatocyte growth factor receptor binding(GO:0005171) |
| 0.7 | 9.5 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.7 | 4.1 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.7 | 6.0 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.7 | 2.0 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.6 | 4.5 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.6 | 6.6 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.6 | 14.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.5 | 3.2 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.5 | 10.7 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.5 | 14.0 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.5 | 40.6 | GO:0005518 | collagen binding(GO:0005518) |
| 0.5 | 4.9 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.5 | 13.3 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.4 | 21.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.4 | 5.6 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.4 | 12.8 | GO:0019956 | chemokine binding(GO:0019956) |
| 0.4 | 5.1 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.4 | 7.1 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.3 | 4.8 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.3 | 3.1 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.3 | 3.4 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.3 | 2.3 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.3 | 1.6 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.3 | 8.1 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.3 | 1.8 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.3 | 4.5 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.3 | 15.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.3 | 27.5 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.3 | 3.0 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.3 | 8.1 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.3 | 7.5 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.3 | 6.0 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.3 | 8.2 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.3 | 2.6 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.2 | 87.7 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.2 | 5.3 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 34.3 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.2 | 5.2 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.2 | 9.4 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.2 | 27.0 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.2 | 21.1 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 0.2 | 5.7 | GO:1901505 | carbohydrate derivative transporter activity(GO:1901505) |
| 0.2 | 5.1 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.2 | 184.0 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.2 | 6.4 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.2 | 0.6 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
| 0.2 | 11.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.2 | 3.3 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 0.2 | 19.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 2.1 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
| 0.2 | 1.6 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.2 | 1.6 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.2 | 2.2 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.2 | 1.1 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.1 | 7.2 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 2.2 | GO:0016918 | retinal binding(GO:0016918) |
| 0.1 | 15.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 0.4 | GO:0022897 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
| 0.1 | 1.3 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.1 | 1.6 | GO:0001164 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.1 | 2.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 6.2 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 0.9 | GO:0019863 | IgE binding(GO:0019863) |
| 0.1 | 7.1 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.1 | 53.0 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.1 | 3.9 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 2.0 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 1.9 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 1.3 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.1 | 0.5 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.1 | 17.4 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 2.8 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.1 | 0.1 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 0.1 | 1.9 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.1 | 2.9 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 0.6 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 6.5 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 0.2 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 0.0 | 0.6 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 1.2 | GO:0001848 | complement binding(GO:0001848) |
| 0.0 | 1.1 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 0.4 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.0 | 0.7 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 4.7 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.6 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.4 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 0.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 0.5 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 1.4 | GO:0042562 | hormone binding(GO:0042562) |
| 0.0 | 0.6 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.7 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 0.5 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 74.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 2.4 | 150.0 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 2.0 | 61.3 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 2.0 | 68.8 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 1.3 | 140.8 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 1.2 | 65.1 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 1.0 | 52.6 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 1.0 | 82.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 1.0 | 30.7 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.9 | 24.7 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.8 | 57.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.7 | 44.2 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.6 | 8.7 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.6 | 10.5 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.6 | 22.6 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.6 | 38.6 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.5 | 36.7 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.5 | 12.8 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.4 | 25.9 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.4 | 27.7 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.4 | 30.1 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.4 | 15.3 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.4 | 8.8 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.3 | 7.3 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.3 | 5.2 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.3 | 23.9 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.2 | 5.7 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.2 | 7.8 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.2 | 16.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.2 | 7.7 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.2 | 3.6 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.1 | 10.6 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 24.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 5.5 | PID FGF PATHWAY | FGF signaling pathway |
| 0.1 | 6.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 3.8 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 3.1 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 2.0 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.1 | 10.7 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 3.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 2.7 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.1 | 3.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 3.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 3.1 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 2.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 1.1 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 6.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.2 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 1.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.6 | PID RAS PATHWAY | Regulation of Ras family activation |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 6.7 | REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
| 2.0 | 38.8 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 1.9 | 166.6 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 1.7 | 87.1 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 1.7 | 15.0 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 1.5 | 27.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 1.5 | 39.8 | REACTOME SHC1 EVENTS IN EGFR SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 1.4 | 39.4 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 1.2 | 13.5 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 1.2 | 44.3 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 1.1 | 43.9 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 1.1 | 85.6 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.9 | 68.6 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.9 | 14.7 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.8 | 17.6 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.7 | 6.4 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.7 | 22.9 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.7 | 23.1 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.6 | 4.8 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.6 | 19.3 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.6 | 13.0 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.6 | 19.7 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.5 | 17.0 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.5 | 12.7 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.5 | 1.8 | REACTOME PI3K EVENTS IN ERBB2 SIGNALING | Genes involved in PI3K events in ERBB2 signaling |
| 0.4 | 9.0 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
| 0.4 | 66.3 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.4 | 18.2 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.4 | 9.1 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.4 | 5.7 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.4 | 5.2 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.4 | 9.4 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.3 | 6.2 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.3 | 6.5 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.3 | 24.4 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.3 | 6.7 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.3 | 9.0 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.2 | 10.7 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.2 | 5.1 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.2 | 9.4 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.2 | 2.8 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.1 | 4.6 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 3.2 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 6.3 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 1.6 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 2.1 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 2.1 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 0.1 | 0.9 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 2.6 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 2.2 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 5.0 | REACTOME EXTRACELLULAR MATRIX ORGANIZATION | Genes involved in Extracellular matrix organization |
| 0.1 | 8.0 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 5.1 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 9.4 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.1 | 9.3 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 5.7 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 12.0 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.1 | 3.3 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.1 | 1.2 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.1 | 0.3 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.1 | 1.1 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 0.1 | 1.8 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 1.0 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.1 | 1.2 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 1.1 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.0 | 0.2 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.0 | 0.6 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 2.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 0.4 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 2.7 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 1.5 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.6 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 1.5 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |