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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOXA3_FOXC2

Z-value: 0.83

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Transcription factors associated with FOXA3_FOXC2

Gene Symbol Gene ID Gene Info
ENSG00000170608.2 forkhead box A3
ENSG00000176692.4 forkhead box C2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXC2hg19_v2_chr16_+_86600857_86600921-0.143.4e-02Click!

Activity profile of FOXA3_FOXC2 motif

Sorted Z-values of FOXA3_FOXC2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_26695013 11.45 ENST00000555059.2
Homeobox protein SEBOX
chr17_-_26694979 11.37 ENST00000438614.1
vitronectin
chr11_-_116708302 10.42 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
apolipoprotein A-I
chr11_+_62186498 8.86 ENST00000278282.2
secretoglobin, family 1A, member 1 (uteroglobin)
chr12_-_92539614 8.83 ENST00000256015.3
B-cell translocation gene 1, anti-proliferative
chr17_-_39684550 8.01 ENST00000455635.1
ENST00000361566.3
keratin 19
chr10_+_71561649 6.61 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
collagen, type XIII, alpha 1
chr4_-_174256276 6.20 ENST00000296503.5
high mobility group box 2
chr14_-_36988882 5.94 ENST00000498187.2
NK2 homeobox 1
chr17_+_72426891 5.76 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr10_+_71561704 5.70 ENST00000520267.1
collagen, type XIII, alpha 1
chr7_+_129906660 5.51 ENST00000222481.4
carboxypeptidase A2 (pancreatic)
chr8_+_97597148 5.50 ENST00000521590.1
syndecan 2
chr6_-_41715128 5.27 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
progastricsin (pepsinogen C)
chr11_-_108464465 5.05 ENST00000525344.1
exophilin 5
chr10_+_71561630 5.03 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
collagen, type XIII, alpha 1
chr4_+_74269956 4.96 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
albumin
chr7_+_112063192 4.37 ENST00000005558.4
interferon-related developmental regulator 1
chr2_+_74120094 4.36 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
actin, gamma 2, smooth muscle, enteric
chr17_-_19290483 4.26 ENST00000395592.2
ENST00000299610.4
microfibrillar-associated protein 4
chr15_+_96869165 4.23 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chr1_-_57431679 4.14 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
complement component 8, beta polypeptide
chr7_-_107643674 3.83 ENST00000222399.6
laminin, beta 1
chr12_+_96588143 3.80 ENST00000228741.3
ENST00000547249.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr20_+_31823792 3.62 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPI fold containing family A, member 1
chr12_-_15038779 3.53 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr7_+_134464414 3.52 ENST00000361901.2
caldesmon 1
chr5_-_137674000 3.45 ENST00000510119.1
ENST00000513970.1
cell division cycle 25C
chr10_-_118032697 3.42 ENST00000439649.3
GDNF family receptor alpha 1
chr7_+_134576317 3.36 ENST00000424922.1
ENST00000495522.1
caldesmon 1
chr11_-_108464321 3.26 ENST00000265843.4
exophilin 5
chr4_-_72649763 3.16 ENST00000513476.1
group-specific component (vitamin D binding protein)
chr10_-_118032979 3.08 ENST00000355422.6
GDNF family receptor alpha 1
chr2_-_21266935 3.00 ENST00000233242.1
apolipoprotein B
chr17_-_26697304 2.97 ENST00000536498.1
vitronectin
chr7_+_134464376 2.81 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr2_-_192711968 2.78 ENST00000304141.4
serum deprivation response
chr2_-_106054952 2.75 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
four and a half LIM domains 2
chr4_-_186456652 2.71 ENST00000284767.5
ENST00000284770.5
PDZ and LIM domain 3
chr4_-_186456766 2.69 ENST00000284771.6
PDZ and LIM domain 3
chr5_+_95998746 2.60 ENST00000508608.1
calpastatin
chr11_-_107582775 2.59 ENST00000305991.2
sarcolipin
chr3_+_142315225 2.58 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
plastin 1
chr22_+_21128167 2.53 ENST00000215727.5
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr5_-_41213607 2.51 ENST00000337836.5
ENST00000433294.1
complement component 6
chr14_-_38064198 2.47 ENST00000250448.2
forkhead box A1
chr3_+_137717571 2.45 ENST00000343735.4
claudin 18
chr14_+_21156915 2.42 ENST00000397990.4
ENST00000555597.1
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr3_-_168864427 2.39 ENST00000468789.1
MDS1 and EVI1 complex locus
chr10_+_124320156 2.27 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr2_-_165424973 2.27 ENST00000543549.1
growth factor receptor-bound protein 14
chr10_+_71562180 2.27 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
collagen, type XIII, alpha 1
chr7_+_73242490 2.26 ENST00000431918.1
claudin 4
chr4_+_147096837 2.26 ENST00000296581.5
ENST00000502781.1
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_+_124320195 2.24 ENST00000359586.6
deleted in malignant brain tumors 1
chrX_+_9431324 2.22 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
transducin (beta)-like 1X-linked
chr2_+_58655461 2.21 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
long intergenic non-protein coding RNA 1122
chr17_+_72427477 2.20 ENST00000342648.5
ENST00000481232.1
G protein-coupled receptor, family C, group 5, member C
chr15_+_80364901 2.14 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
zinc finger, AN1-type domain 6
chr20_+_44519948 2.13 ENST00000354880.5
ENST00000191018.5
cathepsin A
chr11_-_72070206 2.13 ENST00000544382.1
ClpB caseinolytic peptidase B homolog (E. coli)
chr1_+_207277590 2.12 ENST00000367070.3
complement component 4 binding protein, alpha
chr20_+_9049682 2.06 ENST00000334005.3
ENST00000378473.3
phospholipase C, beta 4
chr20_+_44520009 2.05 ENST00000607482.1
ENST00000372459.2
cathepsin A
chr17_-_46688334 2.04 ENST00000239165.7
homeobox B7
chr12_-_120765565 2.03 ENST00000423423.3
ENST00000308366.4
phospholipase A2, group IB (pancreas)
chr18_+_47088401 2.00 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
lipase, endothelial
chr3_+_69985734 2.00 ENST00000314557.6
ENST00000394351.3
microphthalmia-associated transcription factor
chr13_+_73629107 1.94 ENST00000539231.1
Kruppel-like factor 5 (intestinal)
chr2_+_128175997 1.88 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
protein C (inactivator of coagulation factors Va and VIIIa)
chr3_+_148545586 1.88 ENST00000282957.4
ENST00000468341.1
carboxypeptidase B1 (tissue)
chr8_-_23261589 1.86 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
lysyl oxidase-like 2
chr14_-_36990354 1.81 ENST00000518149.1
NK2 homeobox 1
chr3_-_107941230 1.81 ENST00000264538.3
intraflagellar transport 57 homolog (Chlamydomonas)
chr3_+_137728842 1.73 ENST00000183605.5
claudin 18
chr11_-_102401469 1.71 ENST00000260227.4
matrix metallopeptidase 7 (matrilysin, uterine)
chr6_+_161123270 1.69 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chr3_-_99833333 1.66 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
filamin A interacting protein 1-like
chr7_+_134430212 1.62 ENST00000436461.2
caldesmon 1
chr9_-_110251836 1.61 ENST00000374672.4
Kruppel-like factor 4 (gut)
chr17_+_7487146 1.61 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr7_+_134576151 1.60 ENST00000393118.2
caldesmon 1
chr1_+_74701062 1.60 ENST00000326637.3
TNNI3 interacting kinase
chr6_+_125524785 1.59 ENST00000392482.2
tumor protein D52-like 1
chr10_-_126849068 1.59 ENST00000494626.2
ENST00000337195.5
C-terminal binding protein 2
chr1_+_104293028 1.59 ENST00000370079.3
amylase, alpha 1C (salivary)
chr3_+_141106643 1.51 ENST00000514251.1
zinc finger and BTB domain containing 38
chr14_-_94789663 1.49 ENST00000557225.1
ENST00000341584.3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chrX_-_20236970 1.49 ENST00000379548.4
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr4_+_169013666 1.49 ENST00000359299.3
annexin A10
chr18_-_25616519 1.48 ENST00000399380.3
cadherin 2, type 1, N-cadherin (neuronal)
chr4_-_140223614 1.46 ENST00000394223.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr14_-_24664540 1.45 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
transmembrane 9 superfamily member 1
chr4_+_146403912 1.42 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD family member 1
chr7_+_77469439 1.42 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr11_-_66112555 1.40 ENST00000425825.2
ENST00000359957.3
breast cancer metastasis suppressor 1
chr3_+_155588375 1.37 ENST00000295920.7
guanine monphosphate synthase
chr2_-_188312971 1.37 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
calcitonin receptor-like
chr7_+_28452130 1.35 ENST00000357727.2
cAMP responsive element binding protein 5
chr9_-_70490107 1.34 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
COBW domain containing 5
chr10_-_81708854 1.33 ENST00000372292.3
surfactant protein D
chr7_+_106809406 1.32 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HMG-box transcription factor 1
chr8_+_21777159 1.31 ENST00000434536.1
ENST00000252512.9
exportin 7
chr2_+_88047606 1.31 ENST00000359481.4
plasminogen-like B2
chr12_-_102872317 1.31 ENST00000424202.2
insulin-like growth factor 1 (somatomedin C)
chr4_-_103266626 1.30 ENST00000356736.4
solute carrier family 39 (zinc transporter), member 8
chr4_-_70080449 1.29 ENST00000446444.1
UDP glucuronosyltransferase 2 family, polypeptide B11
chr4_-_140223670 1.24 ENST00000394228.1
ENST00000539387.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr3_-_133969673 1.23 ENST00000427044.2
receptor-like tyrosine kinase
chr4_-_186696425 1.22 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr3_-_113897899 1.20 ENST00000383673.2
ENST00000295881.7
dopamine receptor D3
chr16_+_67381289 1.20 ENST00000435835.3
leucine rich repeat containing 36
chr16_+_67381263 1.18 ENST00000541146.1
ENST00000563189.1
ENST00000290940.7
leucine rich repeat containing 36
chr17_+_7476136 1.18 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr10_+_123923105 1.17 ENST00000368999.1
transforming, acidic coiled-coil containing protein 2
chr6_-_87804815 1.16 ENST00000369582.2
glycoprotein hormones, alpha polypeptide
chr15_-_59041768 1.16 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM metallopeptidase domain 10
chr1_-_150669500 1.15 ENST00000271732.3
golgi phosphoprotein 3-like
chr1_+_104159999 1.13 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr6_-_49755019 1.12 ENST00000304801.3
phosphoglycerate kinase 2
chr14_+_51706886 1.11 ENST00000457354.2
thioredoxin-related transmembrane protein 1
chr4_-_70826725 1.10 ENST00000353151.3
casein beta
chr19_+_41257084 1.10 ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chr3_+_135741576 1.09 ENST00000334546.2
protein phosphatase 2, regulatory subunit B'', alpha
chr1_+_151739131 1.08 ENST00000400999.1
ornithine decarboxylase antizyme 3
chr17_-_202579 1.07 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
rabphilin 3A-like (without C2 domains)
chr1_-_43855444 1.06 ENST00000372455.4
mediator complex subunit 8
chr10_-_126849588 1.05 ENST00000411419.2
C-terminal binding protein 2
chr17_-_39041479 1.04 ENST00000167588.3
keratin 20
chr8_-_6420930 1.04 ENST00000325203.5
angiopoietin 2
chr21_-_43786634 1.00 ENST00000291527.2
trefoil factor 1
chr20_+_45338126 0.99 ENST00000359271.2
solute carrier family 2 (facilitated glucose transporter), member 10
chr7_-_25268104 0.98 ENST00000222674.2
neuropeptide VF precursor
chr3_-_114343039 0.98 ENST00000481632.1
zinc finger and BTB domain containing 20
chr8_-_95449155 0.97 ENST00000481490.2
fibrinogen silencer binding protein
chr17_+_8924837 0.97 ENST00000173229.2
netrin 1
chr5_+_179921344 0.96 ENST00000261951.4
CCR4-NOT transcription complex, subunit 6
chr2_+_109223595 0.95 ENST00000410093.1
LIM and senescent cell antigen-like domains 1
chr8_+_19171128 0.94 ENST00000265807.3
SH2 domain containing 4A
chr5_+_179921430 0.94 ENST00000393356.1
CCR4-NOT transcription complex, subunit 6
chr9_-_75567962 0.90 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr12_-_21927736 0.89 ENST00000240662.2
potassium inwardly-rectifying channel, subfamily J, member 8
chr1_+_172389821 0.87 ENST00000367727.4
chromosome 1 open reading frame 105
chr7_+_106505696 0.86 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr1_+_18958008 0.82 ENST00000420770.2
ENST00000400661.3
paired box 7
chr15_-_40600111 0.82 ENST00000543785.2
ENST00000260402.3
phospholipase C, beta 2
chr12_+_58087901 0.80 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr6_-_112575912 0.80 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
laminin, alpha 4
chr21_-_38445011 0.79 ENST00000464265.1
ENST00000399102.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_54405773 0.79 ENST00000371376.1
heat shock protein family B (small), member 11
chr12_+_21525818 0.78 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr3_-_196910721 0.77 ENST00000443183.1
discs, large homolog 1 (Drosophila)
chr7_+_134832808 0.77 ENST00000275767.3
transmembrane protein 140
chr12_-_48099754 0.77 ENST00000380650.4
RNA polymerase II associated protein 3
chr5_+_101569696 0.77 ENST00000597120.1
AC008948.1
chr10_+_105314881 0.76 ENST00000437579.1
neuralized E3 ubiquitin protein ligase 1
chr7_+_106505912 0.76 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr12_-_48099773 0.75 ENST00000432584.3
ENST00000005386.3
RNA polymerase II associated protein 3
chr14_-_25479811 0.75 ENST00000550887.1
syntaxin binding protein 6 (amisyn)
chr4_-_123377880 0.72 ENST00000226730.4
interleukin 2
chr2_-_182545603 0.72 ENST00000295108.3
neuronal differentiation 1
chr19_-_15443318 0.71 ENST00000360016.5
bromodomain containing 4
chr12_+_59989918 0.70 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr14_+_58711539 0.70 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr1_-_246357029 0.69 ENST00000391836.2
SET and MYND domain containing 3
chr1_-_246729544 0.69 ENST00000544618.1
ENST00000366514.4
transcription factor B2, mitochondrial
chr1_+_154540246 0.69 ENST00000368476.3
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr6_-_161085291 0.68 ENST00000316300.5
lipoprotein, Lp(a)
chr9_-_14722715 0.68 ENST00000380911.3
cerberus 1, DAN family BMP antagonist
chr1_-_169555779 0.67 ENST00000367797.3
ENST00000367796.3
coagulation factor V (proaccelerin, labile factor)
chr18_-_3874271 0.67 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
discs, large (Drosophila) homolog-associated protein 1
chr14_+_74034310 0.67 ENST00000538782.1
acyl-CoA thioesterase 2
chr19_+_47421933 0.65 ENST00000404338.3
Rho GTPase activating protein 35
chr12_-_18243075 0.64 ENST00000536890.1
RERG/RAS-like
chr1_-_146696901 0.64 ENST00000369272.3
ENST00000441068.2
flavin containing monooxygenase 5
chr12_-_102591604 0.64 ENST00000329406.4
pro-melanin-concentrating hormone
chr18_-_52626622 0.62 ENST00000591504.1
coiled-coil domain containing 68
chrX_+_99839799 0.61 ENST00000373031.4
tenomodulin
chr7_-_81399438 0.61 ENST00000222390.5
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_-_26056695 0.61 ENST00000343677.2
histone cluster 1, H1c
chr4_+_118955500 0.60 ENST00000296499.5
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr18_-_3874247 0.58 ENST00000581699.1
discs, large (Drosophila) homolog-associated protein 1
chr1_+_152486950 0.57 ENST00000368790.3
cysteine-rich C-terminal 1
chr10_+_35484053 0.57 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
cAMP responsive element modulator
chr1_-_28384598 0.56 ENST00000373864.1
eyes absent homolog 3 (Drosophila)
chr1_+_86934526 0.55 ENST00000394711.1
chloride channel accessory 1
chr5_-_98262240 0.55 ENST00000284049.3
chromodomain helicase DNA binding protein 1
chr3_+_148447887 0.55 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
angiotensin II receptor, type 1
chr20_-_7921090 0.54 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chrX_+_24167746 0.54 ENST00000428571.1
ENST00000539115.1
zinc finger protein, X-linked
chr15_-_59665062 0.53 ENST00000288235.4
myosin IE
chr1_+_18957500 0.53 ENST00000375375.3
paired box 7
chr9_+_70856397 0.52 ENST00000360171.6
COBW domain containing 3
chr6_-_25830785 0.52 ENST00000468082.1
solute carrier family 17 (organic anion transporter), member 1
chr2_+_28974668 0.52 ENST00000296122.6
ENST00000395366.2
protein phosphatase 1, catalytic subunit, beta isozyme
chr3_+_136649311 0.51 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr18_-_3874752 0.51 ENST00000534970.1
discs, large (Drosophila) homolog-associated protein 1
chr11_+_7110165 0.50 ENST00000306904.5
RNA binding motif protein, X-linked-like 2
chr7_-_81399355 0.50 ENST00000457544.2
hepatocyte growth factor (hepapoietin A; scatter factor)
chr15_-_66797172 0.50 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
ribosomal protein L4

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA3_FOXC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.4 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
1.7 5.0 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.6 14.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.6 7.8 GO:0021759 globus pallidus development(GO:0021759)
1.5 8.9 GO:0010193 response to ozone(GO:0010193)
1.5 4.4 GO:0007518 myoblast fate determination(GO:0007518)
1.1 8.0 GO:0008218 bioluminescence(GO:0008218)
1.1 4.2 GO:0009956 radial pattern formation(GO:0009956)
1.0 2.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
1.0 3.8 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.9 3.6 GO:0042710 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.9 5.3 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.9 2.6 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.7 4.4 GO:0090131 mesenchyme migration(GO:0090131)
0.7 8.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.6 4.5 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.6 2.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.6 1.9 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.6 6.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.6 2.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.6 0.6 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.6 6.5 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.6 5.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 1.7 GO:2000048 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.6 2.8 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.5 1.6 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.5 1.6 GO:0071409 negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.5 0.5 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.5 2.6 GO:1902896 terminal web assembly(GO:1902896)
0.5 4.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.5 8.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.4 3.0 GO:0006642 triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269)
0.4 4.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.4 1.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.4 1.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.4 19.6 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.4 1.1 GO:1903487 regulation of lactation(GO:1903487)
0.4 4.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 1.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 1.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 1.2 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.3 0.9 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 1.2 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.3 1.5 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.3 2.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3 5.5 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.3 1.3 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.3 1.0 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.2 3.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2 2.1 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.2 1.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 4.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.9 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 1.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 8.0 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.2 1.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.5 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.2 0.7 GO:2000317 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.2 0.5 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 0.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 0.7 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) synaptic transmission involved in micturition(GO:0060084)
0.2 0.5 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 0.7 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.2 1.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.5 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 3.5 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.4 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 1.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.7 GO:0032571 response to vitamin K(GO:0032571)
0.1 1.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 2.6 GO:0060972 left/right pattern formation(GO:0060972)
0.1 3.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.4 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 4.2 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 0.8 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.0 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.6 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.9 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.8 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1 0.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.7 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.8 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 2.1 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 2.0 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.9 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 2.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 1.5 GO:0006914 autophagy(GO:0006914)
0.1 0.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 1.7 GO:0044849 estrous cycle(GO:0044849)
0.1 1.6 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 1.5 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.1 2.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.9 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.1 1.5 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 1.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.0 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 2.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 0.3 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.7 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 1.1 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 1.2 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.7 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 2.2 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 2.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.8 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 1.0 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.9 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.3 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) gamma-delta T cell differentiation(GO:0042492)
0.0 0.6 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.7 GO:0014904 myotube cell development(GO:0014904)
0.0 0.6 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 1.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 1.0 GO:0035902 response to immobilization stress(GO:0035902)
0.0 11.7 GO:0006936 muscle contraction(GO:0006936)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 1.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 2.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 1.1 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.4 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 1.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.6 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 1.2 GO:0017158 regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 19.6 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
3.6 14.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
3.5 10.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.8 10.6 GO:1990357 terminal web(GO:1990357)
1.3 3.8 GO:0005607 laminin-2 complex(GO:0005607)
0.9 12.9 GO:0030478 actin cap(GO:0030478)
0.7 6.6 GO:0005579 membrane attack complex(GO:0005579)
0.6 4.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.5 1.6 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.5 3.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.4 4.3 GO:0071953 elastic fiber(GO:0071953)
0.4 2.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 5.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 0.9 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 0.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 2.6 GO:0097470 ribbon synapse(GO:0097470)
0.3 1.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.3 1.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 2.3 GO:0005688 U6 snRNP(GO:0005688)
0.2 4.4 GO:0032982 myosin filament(GO:0032982)
0.2 0.8 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 1.5 GO:0097255 R2TP complex(GO:0097255)
0.2 1.8 GO:0044292 dendrite terminus(GO:0044292)
0.1 1.5 GO:0016342 catenin complex(GO:0016342)
0.1 1.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 9.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.9 GO:0042587 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 6.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.3 GO:0042599 lamellar body(GO:0042599)
0.1 1.5 GO:0071141 SMAD protein complex(GO:0071141)
0.1 8.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 2.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.8 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 2.8 GO:0031430 M band(GO:0031430)
0.1 2.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 12.8 GO:0072562 blood microparticle(GO:0072562)
0.1 2.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.5 GO:0005605 basal lamina(GO:0005605)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 6.6 GO:0030018 Z disc(GO:0030018)
0.0 1.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 6.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 4.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.1 GO:0005685 U1 snRNP(GO:0005685)
0.0 2.5 GO:0005902 microvillus(GO:0005902)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 6.4 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 23.2 GO:0005615 extracellular space(GO:0005615)
0.0 1.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0000786 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0 4.9 GO:0016607 nuclear speck(GO:0016607)
0.0 0.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0061695 transferase complex, transferring phosphorus-containing groups(GO:0061695)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.4 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.6 6.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
1.5 8.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.3 4.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.9 6.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.7 3.0 GO:0035473 lipase binding(GO:0035473)
0.6 10.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.6 8.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.5 3.2 GO:0005499 vitamin D binding(GO:0005499)
0.5 4.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.5 12.9 GO:0005523 tropomyosin binding(GO:0005523)
0.4 2.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4 2.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.4 2.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.4 1.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.3 1.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.3 1.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.3 1.6 GO:0031013 troponin I binding(GO:0031013)
0.3 5.0 GO:0015643 toxic substance binding(GO:0015643)
0.3 0.9 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.3 1.1 GO:0016160 amylase activity(GO:0016160)
0.3 2.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 7.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 5.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 0.7 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 1.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 1.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 1.7 GO:1990405 protein antigen binding(GO:1990405)
0.2 1.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 0.6 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 2.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 0.5 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 0.9 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 0.5 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 0.7 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 1.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 1.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 1.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.2 4.5 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 1.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.9 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 0.6 GO:0015265 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.1 13.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.5 GO:0047708 biotinidase activity(GO:0047708)
0.1 23.8 GO:0008201 heparin binding(GO:0008201)
0.1 1.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 4.2 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.8 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 1.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 3.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.7 GO:0016015 morphogen activity(GO:0016015)
0.1 8.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 3.5 GO:0050699 WW domain binding(GO:0050699)
0.1 1.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.8 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.2 GO:0000339 RNA cap binding(GO:0000339)
0.1 1.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 2.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 2.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 1.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 2.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 3.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 4.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.4 GO:0051117 ATPase binding(GO:0051117)
0.0 3.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 1.2 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 11.6 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 5.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 15.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 19.6 NABA COLLAGENS Genes encoding collagen proteins
0.3 25.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 18.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 11.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 6.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 9.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 5.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.1 PID CD40 PATHWAY CD40/CD40L signaling
0.1 1.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 4.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 6.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.6 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 0.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 4.3 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.8 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 2.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.0 10.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 5.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 15.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 6.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 19.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 3.7 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.3 16.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 2.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 5.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.2 3.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 8.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 2.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 19.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 5.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 6.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 2.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 3.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 4.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 10.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 4.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 3.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.3 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.3 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.1 1.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 2.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 2.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.8 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 2.9 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle