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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOXQ1

Z-value: 1.63

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Transcription factors associated with FOXQ1

Gene Symbol Gene ID Gene Info
FOXQ1
ENSG00000164379.4 forkhead box Q1

Activity profile of FOXQ1 motif

Sorted Z-values of FOXQ1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_52456327 27.47 ENST00000556760.1
C14orf166
chromosome 14 open reading frame 166
chr3_-_49066811 26.90 ENST00000442157.1
ENST00000326739.4
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr2_-_225434538 25.92 ENST00000409096.1
CUL3
cullin 3
chr14_+_52456193 24.34 ENST00000261700.3
C14orf166
chromosome 14 open reading frame 166
chr3_-_107777208 23.94 ENST00000398258.3
CD47
CD47 molecule
chr2_-_150444116 23.90 ENST00000428879.1
ENST00000422782.2
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr20_+_30327063 22.04 ENST00000300403.6
ENST00000340513.4
TPX2
TPX2, microtubule-associated
chr10_-_36813162 21.99 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr2_-_151344172 21.83 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr4_-_111119804 21.76 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr11_+_101983176 21.54 ENST00000524575.1
YAP1
Yes-associated protein 1
chr2_-_150444300 20.95 ENST00000303319.5
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr1_-_145826450 20.49 ENST00000462900.2
GPR89A
G protein-coupled receptor 89A
chr1_-_54405773 19.98 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr14_+_56078695 19.94 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr7_-_87856280 18.82 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr12_-_47473557 18.32 ENST00000321382.3
AMIGO2
adhesion molecule with Ig-like domain 2
chr7_-_87856303 18.22 ENST00000394641.3
SRI
sorcin
chr12_-_47473425 18.18 ENST00000550413.1
AMIGO2
adhesion molecule with Ig-like domain 2
chr9_+_42671887 18.07 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chrX_+_119737806 18.00 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr18_-_33702078 17.98 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr1_+_165797024 17.59 ENST00000372212.4
UCK2
uridine-cytidine kinase 2
chr7_+_102988082 17.36 ENST00000292644.3
ENST00000544811.1
PSMC2
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr14_+_56127989 17.07 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr3_+_136649311 16.07 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr5_+_72143988 15.89 ENST00000506351.2
TNPO1
transportin 1
chr12_+_50144381 15.85 ENST00000552370.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr17_+_66521936 15.85 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_-_140223614 15.63 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr17_-_38574169 15.52 ENST00000423485.1
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr12_+_19358228 15.44 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr12_-_76462713 15.15 ENST00000552056.1
NAP1L1
nucleosome assembly protein 1-like 1
chr1_+_145883868 15.07 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr6_-_24666819 14.93 ENST00000341060.3
TDP2
tyrosyl-DNA phosphodiesterase 2
chr3_+_171757346 14.83 ENST00000421757.1
ENST00000415807.2
ENST00000392699.1
FNDC3B
fibronectin type III domain containing 3B
chr12_-_71551652 14.77 ENST00000546561.1
TSPAN8
tetraspanin 8
chr20_+_36373032 14.74 ENST00000373473.1
CTNNBL1
catenin, beta like 1
chr19_-_40331345 14.73 ENST00000597224.1
FBL
fibrillarin
chr1_+_26605618 14.66 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr11_-_14521379 14.52 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
COPB1
coatomer protein complex, subunit beta 1
chr1_+_155179012 13.89 ENST00000609421.1
MTX1
metaxin 1
chr12_-_76478417 13.80 ENST00000552342.1
NAP1L1
nucleosome assembly protein 1-like 1
chr4_-_140223670 13.73 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr12_-_76478386 13.61 ENST00000535020.2
NAP1L1
nucleosome assembly protein 1-like 1
chr3_-_32544900 13.60 ENST00000205636.3
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr11_+_844406 13.55 ENST00000397404.1
TSPAN4
tetraspanin 4
chr13_+_48611665 13.37 ENST00000258662.2
NUDT15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr5_+_65440032 13.25 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr11_-_82997371 13.17 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr11_-_47447970 13.14 ENST00000298852.3
ENST00000530912.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr11_+_108535752 12.96 ENST00000322536.3
DDX10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr3_+_130569429 12.66 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr18_+_3252265 12.55 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr3_+_139063372 12.51 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr20_+_56964253 12.37 ENST00000395802.3
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr1_-_153599732 12.04 ENST00000392623.1
S100A13
S100 calcium binding protein A13
chr5_+_140529630 11.99 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr21_-_33975547 11.97 ENST00000431599.1
C21orf59
chromosome 21 open reading frame 59
chr6_-_131277510 11.85 ENST00000525193.1
ENST00000527659.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr20_-_3185279 11.67 ENST00000354488.3
ENST00000380201.2
DDRGK1
DDRGK domain containing 1
chr1_-_95391315 11.64 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic
chr5_+_118812294 11.64 ENST00000509514.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr3_+_138340049 11.64 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr2_-_106054952 11.60 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr13_+_29233218 11.51 ENST00000380842.4
POMP
proteasome maturation protein
chr14_+_73563735 11.34 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr11_-_82997420 11.32 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr5_-_130500922 11.24 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
HINT1
histidine triad nucleotide binding protein 1
chr7_-_41742697 11.24 ENST00000242208.4
INHBA
inhibin, beta A
chr14_+_39583427 11.14 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2
gem (nuclear organelle) associated protein 2
chr15_+_80351977 11.03 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr15_+_80351910 10.82 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr14_+_35591928 10.59 ENST00000605870.1
ENST00000557404.3
KIAA0391
KIAA0391
chr17_-_36358166 10.47 ENST00000537432.1
TBC1D3
TBC1 domain family, member 3
chr1_-_115259337 10.42 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr7_-_64023441 10.39 ENST00000309683.6
ZNF680
zinc finger protein 680
chr11_-_72070206 10.34 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr15_-_63449663 10.34 ENST00000439025.1
RPS27L
ribosomal protein S27-like
chr12_-_49582593 10.24 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr2_-_55496344 10.17 ENST00000403721.1
ENST00000263629.4
MTIF2
mitochondrial translational initiation factor 2
chr8_+_109455845 10.12 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr12_-_112847108 10.03 ENST00000549847.1
RPL6
ribosomal protein L6
chr17_+_1936687 10.00 ENST00000570477.1
DPH1
diphthamide biosynthesis 1
chr16_+_2820912 9.93 ENST00000570539.1
SRRM2
serine/arginine repetitive matrix 2
chr8_+_30013813 9.87 ENST00000221114.3
DCTN6
dynactin 6
chr12_-_47473642 9.77 ENST00000266581.4
AMIGO2
adhesion molecule with Ig-like domain 2
chr7_+_115862858 9.76 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr1_-_94079648 9.68 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr1_+_95616933 9.63 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr16_-_4395905 9.56 ENST00000571941.1
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr8_+_110551925 9.46 ENST00000395785.2
EBAG9
estrogen receptor binding site associated, antigen, 9
chr10_+_5488564 9.45 ENST00000449083.1
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr12_+_28410128 9.45 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr12_+_53836339 9.35 ENST00000549135.1
PRR13
proline rich 13
chr1_-_150669500 9.33 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr12_-_76478446 9.24 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
NAP1L1
nucleosome assembly protein 1-like 1
chr16_-_58585513 9.11 ENST00000245138.4
ENST00000567285.1
CNOT1
CCR4-NOT transcription complex, subunit 1
chr17_+_18601299 9.10 ENST00000572555.1
ENST00000395902.3
ENST00000449552.2
TRIM16L
tripartite motif containing 16-like
chr8_-_49834299 9.07 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr14_+_102276209 9.07 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr14_-_60636561 9.03 ENST00000536410.2
ENST00000216500.5
DHRS7
dehydrogenase/reductase (SDR family) member 7
chr3_+_138340067 8.99 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr3_+_130569592 8.97 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr14_-_51411194 8.81 ENST00000544180.2
PYGL
phosphorylase, glycogen, liver
chr3_+_159570722 8.69 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr2_+_47596287 8.67 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr3_-_141868293 8.54 ENST00000317104.7
ENST00000494358.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr9_-_128246769 8.52 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr3_-_165555200 8.51 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr6_+_125524785 8.47 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr2_-_55496174 8.27 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
MTIF2
mitochondrial translational initiation factor 2
chr6_-_128841503 8.24 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr15_-_55489097 8.13 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr3_+_158991025 8.09 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr5_-_176836577 8.05 ENST00000253496.3
F12
coagulation factor XII (Hageman factor)
chr8_-_124054484 8.01 ENST00000419562.2
DERL1
derlin 1
chr5_+_118812237 8.00 ENST00000513628.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr8_-_124037890 7.87 ENST00000519018.1
ENST00000523036.1
DERL1
derlin 1
chr8_+_110552046 7.79 ENST00000529931.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr15_-_55541227 7.76 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr3_+_9839335 7.72 ENST00000453882.1
ARPC4-TTLL3
ARPC4-TTLL3 readthrough
chr13_+_52598827 7.70 ENST00000521776.2
UTP14C
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr12_+_56435637 7.66 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr8_+_125486939 7.63 ENST00000303545.3
RNF139
ring finger protein 139
chr14_-_51411146 7.63 ENST00000532462.1
PYGL
phosphorylase, glycogen, liver
chr1_+_74701062 7.58 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr10_+_13652047 7.57 ENST00000601460.1
RP11-295P9.3
Uncharacterized protein
chr12_-_92539614 7.56 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr20_-_31989307 7.53 ENST00000473997.1
ENST00000544843.1
ENST00000346416.2
ENST00000357886.4
ENST00000339269.5
CDK5RAP1
CDK5 regulatory subunit associated protein 1
chr8_+_31497271 7.47 ENST00000520407.1
NRG1
neuregulin 1
chr12_+_1800179 7.42 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr17_-_29233769 7.37 ENST00000581216.1
TEFM
transcription elongation factor, mitochondrial
chr1_+_206557366 7.21 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr10_+_122610687 7.12 ENST00000263461.6
WDR11
WD repeat domain 11
chr9_-_88897426 6.98 ENST00000375991.4
ENST00000326094.4
ISCA1
iron-sulfur cluster assembly 1
chr2_-_188419200 6.97 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chrX_+_107288197 6.97 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr20_+_34802295 6.91 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr22_-_36236623 6.90 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_+_157154578 6.81 ENST00000295927.3
PTX3
pentraxin 3, long
chr6_+_88182643 6.74 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
SLC35A1
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr20_-_33732952 6.71 ENST00000541621.1
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr3_-_196911002 6.67 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr2_+_163175394 6.58 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr16_-_10652993 6.57 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr10_+_5454505 6.51 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chrX_-_99891796 6.51 ENST00000373020.4
TSPAN6
tetraspanin 6
chr2_+_109237717 6.42 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr17_+_79953310 6.10 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr10_+_51572408 6.06 ENST00000374082.1
NCOA4
nuclear receptor coactivator 4
chr17_+_34171081 6.03 ENST00000585577.1
TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr16_+_69958887 5.94 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr8_-_49833978 5.92 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr12_+_21168630 5.87 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr6_+_37321823 5.86 ENST00000487950.1
ENST00000469731.1
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr3_+_69985734 5.85 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr15_-_30113676 5.83 ENST00000400011.2
TJP1
tight junction protein 1
chr17_-_17485731 5.76 ENST00000395783.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr18_+_21032781 5.75 ENST00000339486.3
RIOK3
RIO kinase 3
chr5_+_102201722 5.72 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr15_+_41549105 5.70 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr17_-_29233221 5.69 ENST00000580840.1
TEFM
transcription elongation factor, mitochondrial
chr22_-_18257249 5.68 ENST00000399765.1
ENST00000399767.1
ENST00000399774.3
BID
BH3 interacting domain death agonist
chr12_-_49582978 5.52 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr1_-_24306835 5.47 ENST00000484146.2
SRSF10
serine/arginine-rich splicing factor 10
chrX_-_41449204 5.42 ENST00000378179.3
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr7_-_124569991 5.41 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1
protection of telomeres 1
chr2_-_165424973 5.35 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr6_-_114194483 5.32 ENST00000434296.2
RP1-249H1.4
RP1-249H1.4
chr2_+_143635067 5.29 ENST00000264170.4
KYNU
kynureninase
chr1_-_227505289 5.27 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr5_+_140579162 5.24 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chr11_-_60674037 5.10 ENST00000541371.1
ENST00000227524.4
PRPF19
pre-mRNA processing factor 19
chr17_-_60142609 4.98 ENST00000397786.2
MED13
mediator complex subunit 13
chr11_-_102668879 4.98 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr3_+_33840050 4.94 ENST00000457054.2
ENST00000413073.1
PDCD6IP
programmed cell death 6 interacting protein
chr4_-_103266626 4.92 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr11_-_27723158 4.91 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr3_-_128902759 4.91 ENST00000422453.2
ENST00000504813.1
ENST00000512338.1
CNBP
CCHC-type zinc finger, nucleic acid binding protein
chr8_-_95487331 4.86 ENST00000336148.5
RAD54B
RAD54 homolog B (S. cerevisiae)
chr8_-_124054587 4.82 ENST00000259512.4
DERL1
derlin 1
chr14_+_35591858 4.79 ENST00000603544.1
KIAA0391
KIAA0391
chr1_-_202927490 4.77 ENST00000340990.5
ADIPOR1
adiponectin receptor 1
chr3_+_130650738 4.75 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr7_-_32529973 4.72 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_+_1283639 4.71 ENST00000303400.4
ENST00000505177.2
ENST00000503653.1
ENST00000264750.6
ENST00000502558.1
ENST00000452175.2
ENST00000514708.1
MAEA
macrophage erythroblast attacher
chr22_-_39268308 4.71 ENST00000407418.3
CBX6
chromobox homolog 6
chr10_+_35484793 4.71 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr20_+_44035847 4.71 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr14_-_20801427 4.64 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr5_+_140625147 4.61 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr7_-_72993033 4.57 ENST00000305632.5
TBL2
transducin (beta)-like 2
chr7_-_26578407 4.54 ENST00000242109.3
KIAA0087
KIAA0087
chr4_+_146403912 4.52 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr15_+_49715293 4.46 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr1_+_236686717 4.46 ENST00000341872.6
ENST00000450372.2
LGALS8
lectin, galactoside-binding, soluble, 8
chr12_+_96588143 4.41 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr1_+_84873913 4.26 ENST00000370662.3
DNASE2B
deoxyribonuclease II beta
chr2_-_188419078 4.25 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXQ1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 25.9 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
6.0 18.0 GO:0002188 translation reinitiation(GO:0002188)
5.4 16.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
5.3 37.0 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
5.0 15.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
4.5 26.9 GO:0006177 GMP biosynthetic process(GO:0006177)
4.4 17.6 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
4.4 26.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
4.3 51.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
3.7 11.2 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
3.7 14.7 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
3.6 21.8 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
3.4 20.7 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
3.3 13.4 GO:0006203 dGTP catabolic process(GO:0006203)
3.3 16.4 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
3.3 19.6 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
3.1 18.4 GO:0032790 ribosome disassembly(GO:0032790)
2.9 11.7 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
2.9 8.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
2.8 8.5 GO:0014016 neuroblast differentiation(GO:0014016)
2.6 15.9 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
2.6 15.4 GO:0090646 mitochondrial tRNA processing(GO:0090646)
2.3 7.0 GO:0097052 tryptophan catabolic process to acetyl-CoA(GO:0019442) L-kynurenine metabolic process(GO:0097052)
2.3 11.6 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
2.3 22.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
2.2 6.7 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
2.2 6.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
2.1 18.6 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
2.0 8.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.9 5.8 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
1.9 7.7 GO:0018094 protein polyglycylation(GO:0018094)
1.9 5.8 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
1.9 48.4 GO:0009235 cobalamin metabolic process(GO:0009235)
1.7 5.0 GO:0044278 cell wall disruption in other organism(GO:0044278)
1.6 4.9 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
1.6 4.9 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.6 30.8 GO:0008228 opsonization(GO:0008228)
1.6 11.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
1.6 20.6 GO:0070986 left/right axis specification(GO:0070986)
1.6 15.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
1.5 12.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.5 13.7 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
1.5 7.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
1.5 4.5 GO:0060437 lung growth(GO:0060437)
1.5 13.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.5 13.1 GO:0006390 mitochondrial DNA replication(GO:0006264) transcription from mitochondrial promoter(GO:0006390)
1.4 5.7 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.4 8.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
1.3 16.0 GO:0051451 myoblast migration(GO:0051451)
1.3 2.6 GO:0044211 CTP salvage(GO:0044211)
1.3 7.8 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.3 10.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
1.2 30.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
1.2 1.2 GO:0050787 detoxification of mercury ion(GO:0050787)
1.2 15.4 GO:0061458 reproductive system development(GO:0061458)
1.2 7.0 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.1 6.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.1 7.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
1.1 15.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.1 13.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
1.0 15.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
1.0 6.7 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
1.0 5.7 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.9 10.2 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.9 2.7 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.9 21.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.9 4.5 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.8 5.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.8 11.9 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.8 21.9 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.8 5.9 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.8 49.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.8 3.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.8 7.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.8 9.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.8 17.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.8 3.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.7 5.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.7 11.5 GO:0043248 proteasome assembly(GO:0043248)
0.7 9.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.7 2.7 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.7 10.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.7 6.7 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.7 4.7 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.7 6.6 GO:0070836 caveola assembly(GO:0070836)
0.7 6.5 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.6 22.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.6 4.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.6 4.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.6 10.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.5 5.4 GO:0051096 telomere assembly(GO:0032202) positive regulation of helicase activity(GO:0051096)
0.5 4.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.5 3.6 GO:0009597 detection of virus(GO:0009597)
0.5 14.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.5 1.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.5 15.8 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.4 2.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.4 6.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.4 2.6 GO:0030916 otic vesicle formation(GO:0030916)
0.4 10.3 GO:0006978 ribosomal small subunit assembly(GO:0000028) DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.4 28.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 55.3 GO:0006334 nucleosome assembly(GO:0006334)
0.4 1.6 GO:0006828 manganese ion transport(GO:0006828)
0.4 17.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.4 3.7 GO:0032808 lacrimal gland development(GO:0032808)
0.4 10.4 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.4 9.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.3 11.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 1.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.0 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.3 5.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.3 1.7 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.3 11.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 3.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.3 3.5 GO:0070307 lens fiber cell development(GO:0070307)
0.3 7.6 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.3 1.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.3 0.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 0.6 GO:0060164 midbrain-hindbrain boundary morphogenesis(GO:0021555) cell-cell signaling involved in cell fate commitment(GO:0045168) regulation of timing of neuron differentiation(GO:0060164)
0.3 1.4 GO:0097338 response to clozapine(GO:0097338)
0.3 2.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.3 0.8 GO:0002027 regulation of heart rate(GO:0002027)
0.3 4.9 GO:0006312 mitotic recombination(GO:0006312)
0.2 10.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 0.5 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.2 0.9 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 5.0 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.2 1.9 GO:0016139 glycoside catabolic process(GO:0016139)
0.2 1.4 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.2 7.7 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.2 12.5 GO:0070527 platelet aggregation(GO:0070527)
0.2 2.9 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 1.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 1.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.2 14.7 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.2 9.1 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 4.6 GO:0001825 blastocyst formation(GO:0001825)
0.2 6.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 11.2 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.2 14.5 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.2 6.4 GO:1903393 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.2 1.2 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.2 7.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.2 4.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.2 12.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 6.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 0.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.2 0.6 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 5.0 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 5.9 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 4.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 11.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 3.0 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 5.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 8.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 2.4 GO:0010842 retina layer formation(GO:0010842)
0.1 1.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 5.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 26.2 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.3 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.7 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 1.8 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 2.7 GO:0010447 response to acidic pH(GO:0010447)
0.1 5.8 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.3 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 1.3 GO:0005513 detection of calcium ion(GO:0005513)
0.1 2.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 8.8 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 8.8 GO:0006302 double-strand break repair(GO:0006302)
0.1 4.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 4.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 8.1 GO:0032874 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.1 0.3 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 1.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.7 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 2.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 19.6 GO:0001558 regulation of cell growth(GO:0001558)
0.0 5.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 2.7 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 2.6 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 1.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 1.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0046785 microtubule polymerization(GO:0046785)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 51.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
5.3 37.0 GO:0044326 dendritic spine neck(GO:0044326)
5.2 15.5 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
5.2 20.7 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
4.9 14.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
4.3 21.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
3.7 11.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
3.1 15.4 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
2.9 25.9 GO:0005827 polar microtubule(GO:0005827)
2.5 30.5 GO:0031595 nuclear proteasome complex(GO:0031595)
2.4 9.6 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.6 4.7 GO:0005826 actomyosin contractile ring(GO:0005826) GID complex(GO:0034657)
1.5 14.5 GO:0030126 COPI vesicle coat(GO:0030126)
1.4 11.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.4 16.6 GO:0043203 axon hillock(GO:0043203)
1.1 10.1 GO:0072546 ER membrane protein complex(GO:0072546)
1.1 7.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
1.0 17.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.0 5.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
1.0 3.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.9 13.7 GO:0005869 dynactin complex(GO:0005869)
0.9 9.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.9 20.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.9 17.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.8 11.9 GO:0008091 spectrin(GO:0008091)
0.7 7.2 GO:0044327 dendritic spine head(GO:0044327)
0.7 5.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.7 4.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.7 2.7 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.7 18.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.6 7.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.6 6.7 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.5 44.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.5 5.4 GO:0070187 telosome(GO:0070187)
0.5 8.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 20.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.5 8.3 GO:0000974 Prp19 complex(GO:0000974)
0.5 48.5 GO:0015935 small ribosomal subunit(GO:0015935)
0.5 8.5 GO:0031932 TORC2 complex(GO:0031932)
0.5 18.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 28.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4 7.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 6.1 GO:0044754 autolysosome(GO:0044754)
0.4 1.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.4 2.6 GO:0097452 GAIT complex(GO:0097452)
0.3 5.4 GO:0005652 nuclear lamina(GO:0005652)
0.3 7.7 GO:0032040 small-subunit processome(GO:0032040)
0.3 14.9 GO:0016235 aggresome(GO:0016235)
0.3 1.1 GO:0032279 asymmetric synapse(GO:0032279)
0.3 6.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.3 44.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 13.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.3 15.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 11.6 GO:0031430 M band(GO:0031430)
0.2 20.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.2 1.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 11.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 2.6 GO:0097542 ciliary tip(GO:0097542)
0.2 5.9 GO:0035861 site of double-strand break(GO:0035861)
0.2 1.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 5.8 GO:0005921 gap junction(GO:0005921)
0.2 4.5 GO:0071141 SMAD protein complex(GO:0071141)
0.2 6.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 40.5 GO:0005802 trans-Golgi network(GO:0005802)
0.2 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 19.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 3.9 GO:0071564 npBAF complex(GO:0071564)
0.2 10.8 GO:0015030 Cajal body(GO:0015030)
0.2 22.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 4.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 5.0 GO:0016592 mediator complex(GO:0016592)
0.1 8.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 15.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.8 GO:0032433 filopodium tip(GO:0032433)
0.1 24.6 GO:0005681 spliceosomal complex(GO:0005681)
0.1 5.3 GO:0010008 endosome membrane(GO:0010008)
0.1 8.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 15.4 GO:0034399 nuclear periphery(GO:0034399)
0.1 11.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 5.7 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 4.7 GO:0031519 PcG protein complex(GO:0031519)
0.1 12.5 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 6.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 6.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 54.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 7.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.6 GO:0005801 cis-Golgi network(GO:0005801)
0.1 8.1 GO:0030027 lamellipodium(GO:0030027)
0.1 0.7 GO:0043194 axon initial segment(GO:0043194)
0.1 24.7 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.1 8.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 15.3 GO:0016607 nuclear speck(GO:0016607)
0.1 8.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 2.6 GO:0005901 caveola(GO:0005901)
0.0 2.3 GO:0016020 membrane(GO:0016020)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.5 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 1.3 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 26.9 GO:0003938 IMP dehydrogenase activity(GO:0003938)
6.5 25.9 GO:0031208 POZ domain binding(GO:0031208)
5.2 15.5 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
5.0 14.9 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
4.6 13.7 GO:0033149 FFAT motif binding(GO:0033149)
4.5 13.4 GO:0035529 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
4.4 22.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
4.1 16.4 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
3.7 11.2 GO:0070699 type II activin receptor binding(GO:0070699)
3.6 21.8 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
3.3 19.6 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
3.3 13.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
3.2 16.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
2.9 20.2 GO:0004849 uridine kinase activity(GO:0004849)
2.8 30.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
2.6 15.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
2.4 23.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
2.1 8.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
1.9 7.7 GO:0070735 protein-glycine ligase activity(GO:0070735)
1.9 5.8 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.8 7.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.7 51.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
1.6 4.9 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.6 4.9 GO:0015616 DNA translocase activity(GO:0015616)
1.5 15.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.4 5.7 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.4 4.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
1.3 18.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.2 4.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
1.2 22.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.2 11.9 GO:0042731 PH domain binding(GO:0042731)
1.1 20.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.1 42.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.0 14.7 GO:0030215 semaphorin receptor binding(GO:0030215)
1.0 27.6 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
1.0 14.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
1.0 15.4 GO:0004526 ribonuclease P activity(GO:0004526)
1.0 6.7 GO:0050733 RS domain binding(GO:0050733)
1.0 7.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.9 26.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.9 2.7 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.9 16.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.9 20.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.9 6.8 GO:0001849 complement component C1q binding(GO:0001849)
0.8 6.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.8 3.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.8 15.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.8 24.6 GO:0070064 proline-rich region binding(GO:0070064)
0.7 8.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.7 7.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.7 4.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.7 2.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.7 9.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.6 12.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.6 6.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6 35.3 GO:0019894 kinesin binding(GO:0019894)
0.6 6.7 GO:0097016 L27 domain binding(GO:0097016)
0.6 12.0 GO:0050786 RAGE receptor binding(GO:0050786)
0.6 21.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.6 8.0 GO:0051787 misfolded protein binding(GO:0051787)
0.6 1.7 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.6 29.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 3.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.5 17.6 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.5 2.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.5 5.8 GO:0089720 caspase binding(GO:0089720)
0.5 7.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.5 5.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.5 8.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.5 9.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.4 2.7 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.4 3.5 GO:0008172 S-methyltransferase activity(GO:0008172)
0.4 15.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 10.7 GO:0008198 ferrous iron binding(GO:0008198)
0.4 3.9 GO:0031013 troponin I binding(GO:0031013)
0.4 4.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.4 5.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.4 9.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 4.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 5.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 11.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 3.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 7.8 GO:0031489 myosin V binding(GO:0031489)
0.3 0.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 18.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 5.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 1.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 1.5 GO:0017018 myosin phosphatase activity(GO:0017018)
0.2 16.6 GO:0050681 androgen receptor binding(GO:0050681)
0.2 1.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 4.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 11.2 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.7 GO:0051425 PTB domain binding(GO:0051425)
0.2 1.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 36.3 GO:0005178 integrin binding(GO:0005178)
0.2 5.7 GO:0005123 death receptor binding(GO:0005123)
0.2 0.6 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.6 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 5.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 39.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 2.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 2.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 12.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 1.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 3.5 GO:0005109 frizzled binding(GO:0005109)
0.1 1.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 7.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 3.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 16.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 10.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 7.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.9 GO:0035198 miRNA binding(GO:0035198)
0.1 0.3 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 2.9 GO:0004386 helicase activity(GO:0004386)
0.1 6.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 9.8 GO:0042393 histone binding(GO:0042393)
0.1 9.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 4.2 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.0 1.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 2.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 11.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 7.5 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 6.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 3.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 3.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0042826 histone deacetylase binding(GO:0042826)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 25.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.5 40.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.4 2.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.4 15.8 PID ALK1 PATHWAY ALK1 signaling events
0.4 22.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.4 35.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.4 23.5 PID PLK1 PATHWAY PLK1 signaling events
0.4 14.9 PID CD40 PATHWAY CD40/CD40L signaling
0.3 5.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 11.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 17.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 9.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.3 11.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 8.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.3 6.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 6.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 17.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 5.3 PID INSULIN PATHWAY Insulin Pathway
0.2 6.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 9.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 5.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 17.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 5.9 PID ATM PATHWAY ATM pathway
0.1 6.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 13.1 PID E2F PATHWAY E2F transcription factor network
0.1 6.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 7.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 5.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 6.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 2.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 5.3 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 5.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.7 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 9.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 3.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 26.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.5 14.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
1.4 22.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.3 19.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.0 21.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.9 27.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.9 15.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.9 10.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.8 16.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.7 9.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.7 23.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.6 16.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.6 15.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 17.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.5 17.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.5 8.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.5 25.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.4 30.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.4 13.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 6.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.4 4.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.4 7.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.4 32.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.4 23.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.4 6.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 7.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 6.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 6.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.3 5.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 6.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.3 8.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.3 5.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.2 2.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 3.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 6.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 5.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 5.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 11.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 6.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 7.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 6.9 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 6.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 10.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 19.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 12.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 6.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 11.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 15.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.7 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends