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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GAGAACU

Z-value: 0.07

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miRNA associated with seed GAGAACU

NamemiRBASE accession
hsa-miR-146a-5p
MIMAT0000449
hsa-miR-146b-5p
MIMAT0002809
hsa-miR-7153-5p
MIMAT0028216

Activity profile of GAGAACU motif

Sorted Z-values of GAGAACU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_13726510 0.21 ENST00000322247.3
ENST00000592976.1
ENST00000402563.1
ENST00000591269.1
FAM210A
family with sequence similarity 210, member A
chr8_+_56014949 0.17 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr2_+_85198216 0.16 ENST00000456682.1
ENST00000409785.4
KCMF1
potassium channel modulatory factor 1
chr18_+_11981427 0.13 ENST00000269159.3
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr15_-_52821247 0.11 ENST00000399231.3
ENST00000399233.2
MYO5A
myosin VA (heavy chain 12, myoxin)
chr16_-_69368774 0.10 ENST00000562949.1
RP11-343C2.12
Conserved oligomeric Golgi complex subunit 8
chr15_+_92396920 0.09 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr16_-_69364467 0.09 ENST00000288022.1
PDF
peptide deformylase (mitochondrial)
chr2_-_208030647 0.08 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr17_-_41174424 0.08 ENST00000355653.3
VAT1
vesicle amine transport 1
chr6_+_160390102 0.07 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr1_-_179198702 0.07 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr3_+_11314099 0.05 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
ATG7
autophagy related 7
chr13_+_100153665 0.05 ENST00000376387.4
TM9SF2
transmembrane 9 superfamily member 2
chr6_-_90121938 0.05 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr9_+_71320596 0.04 ENST00000265382.3
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr14_-_25519095 0.04 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr8_-_89339705 0.04 ENST00000286614.6
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr3_-_125094093 0.03 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
ZNF148
zinc finger protein 148
chr18_+_19749386 0.03 ENST00000269216.3
GATA6
GATA binding protein 6
chr9_-_33264676 0.03 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr14_-_68141535 0.03 ENST00000554659.1
VTI1B
vesicle transport through interaction with t-SNAREs 1B
chr17_-_30669138 0.02 ENST00000225805.4
ENST00000577809.1
C17orf75
chromosome 17 open reading frame 75
chr3_-_79068594 0.02 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr17_+_28804380 0.02 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
GOSR1
golgi SNAP receptor complex member 1
chr4_-_41750922 0.01 ENST00000226382.2
PHOX2B
paired-like homeobox 2b
chr20_+_62795827 0.01 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr1_+_26737253 0.01 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr6_-_24911195 0.01 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr2_+_113239710 0.01 ENST00000233336.6
TTL
tubulin tyrosine ligase
chr17_-_8055747 0.01 ENST00000317276.4
ENST00000581703.1
PER1
period circadian clock 1
chr10_+_120967072 0.01 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr17_-_38020392 0.01 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr3_-_138553594 0.01 ENST00000477593.1
ENST00000483968.1
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr10_+_88516396 0.01 ENST00000372037.3
BMPR1A
bone morphogenetic protein receptor, type IA
chr11_-_36531774 0.00 ENST00000348124.5
ENST00000526995.1
TRAF6
TNF receptor-associated factor 6, E3 ubiquitin protein ligase
chr9_-_34589700 0.00 ENST00000351266.4
CNTFR
ciliary neurotrophic factor receptor
chr1_+_32573636 0.00 ENST00000373625.3
KPNA6
karyopherin alpha 6 (importin alpha 7)
chrX_-_41782249 0.00 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)

Network of associatons between targets according to the STRING database.

First level regulatory network of GAGAACU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.1 GO:0051643 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643)
0.0 0.1 GO:1901859 late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.0 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.0 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)